184 results on '"Lynch, Anthony M."'
Search Results
2. Error-corrected next generation sequencing – Promises and challenges for genotoxicity and cancer risk assessment
3. Error-corrected next-generation sequencing to advance nonclinical genotoxicity and carcinogenicity testing
4. Improving the Assessment of Risk Factors Relevant to Potential Carcinogenicity of Gene Therapies: A Consensus Article.
5. N-Nitrosodimethylamine investigations in Muta™Mouse define point-of-departure values and demonstrate less-than-additive somatic mutant frequency accumulations
6. Inter-laboratory automation of the in vitro micronucleus assay using imaging flow cytometry and deep learning
7. Ames test study designs for nitrosamine mutagenicity testing: qualitative and quantitative analysis of key assay parameters.
8. Ames Test study designs for nitrosamine mutagenicity testing: qualitative and quantitative analysis of key assay parameters
9. Photosafety Testing of Drugs
10. Next Generation Sequencing Workshop at the Royal Society of Medicine (London, May 2022): how genomics is on the path to modernizing genetic toxicology
11. Development of an in vitro PIG-A gene mutation assay in human cells
12. Enzymic and Interindividual Differences in the Human Metabolism of Heterocyclic Amines
13. Considerations on photochemical genotoxicity. II: Report of the 2009 International Workshop on Genotoxicity Testing Working Group
14. Workshop summary: Top concentration for in vitro mammalian cell genotoxicity assays; and report from working group on toxicity measures and top concentration for in vitro cytogenetics assays (chromosome aberrations and micronucleus)
15. APSS Yearbook 1974-75. A Compilation of Current Educational Practices.
16. Responsibility for Educational Tasks: Role Perceptions in West Virginia.
17. A molecular beacon approach to detecting RAD52 expression in response to DNA damage in human cells
18. An evaluation of chemical photoreactivity and the relationship to phototoxicity
19. An evaluation of chemical photoreactivity and the relationship to photogenotoxicity
20. Inter-laboratory automation of thein vitromicronucleus assay using imaging flow cytometry and deep learning
21. Evaluation of the Litron In Vitro MicroFlow ® Kit for the flow cytometric enumeration of micronuclei (MN) in mammalian cells
22. Detecting genotoxic effects of potential clastogens: An in vivo study using the transgenic lacZ plasmid and the Muta™Mouse model
23. Interlaboratory assessment of the GreenScreen HC GADD45a-GFP genotoxicity screening assay: An enabling study for independent validation as an alternative method
24. Is Muta™Mouse insensitive to clastogens?
25. Interlaboratory evaluation of a flow cytometric, high content in vitro micronucleus assay
26. The in vivo rat skin photomicronucleus assay: phototoxicity and photogenotoxicity evaluation of six fluoroquinolones
27. The 3T3 neutral red uptake phototoxicity test: Practical experience and implications for phototoxicity testing – The report of an ECVAM–EFPIA workshop
28. Evaluating the genotoxicity of topoisomerase-targeted antibiotics
29. International Pig-a gene mutation assay trial: Evaluation of transferability across 14 laboratories
30. International Pig-a gene mutation assay trial (Stage III): Results with N-methyl-N-nitrosourea
31. New and emerging technologies for genetic toxicity testing
32. Development and characterization of an in vivo skin photomicronucleus assay in rats
33. Targets and mechanisms of chemically induced aneuploidy. Part 1 of the report of the 2017 IWGT workgroup on assessing the risk of aneugens for carcinogenesis and hereditary diseases
34. Role of aneuploidy in the carcinogenic process: Part 3 of the report of the 2017 IWGT workgroup on assessing the risk of aneugens for carcinogenesis and hereditary diseases
35. Analysis of 75 marketed pharmaceuticals using the GADD45a-GFP ‘GreenScreen HC’ genotoxicity assay
36. Early events in the mammalian response to DNA double-strand breaks
37. Cycloheximide and disulfoton are positive in the photoclastogencity assay but do not absorb UV irradiation: another example of pseudophotoclastogenicity?
38. Flow Cytometric Analysis of Micronuclei in Peripheral Blood Reticulocytes III. An Efficient Method of Monitoring Chromosomal Damage in the Beagle Dog
39. DNA damage responses after exposure to DNA-based products
40. The results of five coded compounds: genistein, metaproterenol, rotenone, p-anisidine and resorcinol tested in the pH 6.7 Syrian hamster embryo cell morphological transformation assay
41. Evaluating the genetic toxicology of DNA-based products using existing genetic toxicology assays
42. Enzymic and Interindividual Differences in the Human Metabolism of Heterocyclic Amines
43. Development of anin vitro PIG-Agene mutation assay in human cells
44. Genotoxicity assessment of peptide/protein-related biotherapeutics: points to consider before testing
45. The 3T3 neutral red uptake phototoxicity test: Practical experience and implications for pototoxicity testing
46. The in vivo Pig-a assay: A report of the International Workshop On Genotoxicity Testing (IWGT) Workgroup
47. Brain function predictors and outcome of weight loss and weight loss maintenance
48. Non-clinical development of ozanezumab: a humanised antibody targeting the amino terminus of neurite outgrowth inhibitor A (Nogo-A)
49. Genotoxicity assessment of peptide/ protein-related biotherapeutics: points to consider before testing.
50. Review of the performance of the 3T3 NRU in vitro phototoxicity assay in the pharmaceutical industry
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