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6. A 20-year retrospective analysis of deep venous thrombosis and pulmonary embolism among combat casualties requiring damage control laparotomy at US Military Role 2 surgical units

Author

Cobler-Lichter, Michael D., Collie, Brianna L., Delamater, Jessica M., Shagabayeva, Larisa, Lyons, Nicole B., Bustillos, Luciana Tito, Namias, Nicholas, Stallings, Jonathan D., Gross, Kirby R., Buzzelli, Mark D., Gurney, Jennifer, Proctor, Kenneth G., and Wetstein, Paul J.

Published
2024
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19. Optimal Timing for Initiation of Thromboprophylaxis After Hepatic Angioembolization

Author

Collie, Brianna L., primary, Lyons, Nicole B., additional, Goddard, Logan, additional, Cobler-Lichter, Michael D., additional, Delamater, Jessica M., additional, Shagabayeva, Larisa, additional, Lineen, Edward B., additional, Schulman, Carl I., additional, Proctor, Kenneth G., additional, Meizoso, Jonathan P., additional, Namias, Nicholas, additional, and Ginzburg, Enrique, additional

Published
2024
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22. Early Detection of Ventilator-associated Pneumonia From Exhaled Breath in Intensive Care Unit Patients.

Author

Bakali, Umer, Killawala, Chitvan, Monteagudo, Evelise, Cobler-Lichter, Michael D., Tito, Luciana, Delamater, Jessica, Shagabayeva, Larisa, Collie, Brianna L., Lyons, Nicole B., Dikici, Emre, Deo, Sapna K., Daunert, Sylvia, and Schulman, Carl I.

Abstract

Objective: Evaluate associations between volatile organic compounds (VOCs) in heat and moisture exchange (HME) filters and the presence of ventilator-associated pneumonia (VAP). Background: Clinical diagnostic criteria for VAP have poor interobserver reliability, and cultures are slow to result. Exhaled breath contains VOCs related to gram-negative bacterial proliferation, the most identified organisms in VAP. We hypothesized that exhaled VOCs on HME filters can predict nascent VAP in mechanically ventilated intensive care unit patients. Methods: Gas chromatography-mass spectrometry was used to analyze 111 HME filters from 12 intubated patients who developed VAP. Identities and relative amounts of VOCs were associated with dates of clinical suspicion and culture confirmation of VAP. Matched pairs t tests were performed to compare VOC abundances in HME filters collected within 3 days pre and postclinical suspicion of VAP (pneumonia days), versus outside of these days (nonpneumonia days). A receiver operating characteristic curve was generated to determine the diagnostic potential of VOCs. Results: Carbon disulfide, associated with the proliferation of certain gram-negative bacteria, was found in samples collected during pneumonia days for 11 of 12 patients. Carbon disulfide levels were significantly greater (P = 0.0163) for filters on pneumonia days. The Area Under the Curve of the Reciever Operating Characteristic curve (AUC ROC) for carbon disulfide was 0.649 (95% CI: 0.419-0.88). Conclusions: Carbon disulfide associated with gram-negative VAP can be identified on HME filters up to 3 days before the initial clinical suspicion, and approximately a week before culture confirmation. This suggests VOC sensors may have potential as an adjunctive method for early detection of VAP. [ABSTRACT FROM AUTHOR]

Published
2024
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31. Management of lower extremity vascular injuries in pediatric trauma patients: 20-year experience at a level 1 trauma center

Author

Lyons, Nicole B, primary, Berg, Arthur, additional, Collie, Brianna L, additional, Meizoso, Jonathan P, additional, Sola, Juan E, additional, Thorson, Chad M, additional, Proctor, Kenneth G, additional, Namias, Nicholas, additional, Pizano, Louis R, additional, Marttos, Antonio C, additional, and Sciarretta, Jason D, additional

Published
2024
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32. 1540: HIGH RATE OF PULMONARY EMBOLISM IN INTERNATIONALLY TRANSFERRED TRAUMA PATIENTS

Author

Tito Bustillos, Luciana, primary, Collie, Brianna, additional, Lyons, Nicole B., additional, Ramsey, Walter A., additional, O’Neil, Christopher F., additional, Delamater, Jessica M., additional, Cobler-Lichter, Michael D., additional, Shagabayeva, Larisa, additional, Ginzburg, Enrique, additional, Meizoso, Jonathan, additional, Proctor, Kenneth G., additional, Parker, Brandon M., additional, Namias, Nicholas, additional, and Pust, Gerd, additional

Published
2023
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33. Admission to a Verified Pediatric Trauma Center is Associated With Improved Outcomes in Severely Injured Children

Author

Ramsey, Walter A., primary, Huerta, Carlos T., additional, O'Neil, Christopher F., additional, Stottlemyre, Rachael L., additional, Saberi, Rebecca A., additional, Gilna, Gareth P., additional, Lyons, Nicole B., additional, Collie, Brianna L., additional, Parker, Brandon M., additional, Perez, Eduardo A., additional, Sola, Juan E., additional, Proctor, Kenneth G., additional, Namias, Nicholas, additional, Thorson, Chad M., additional, and Meizoso, Jonathan P., additional

Published
2023
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34. Immediate Versus Delayed Surgical Management of Infant Cryptorchidism With Inguinal Hernia

Author

Ramsey, Walter A., primary, Huerta, Carlos T., additional, Jones, Alexis K., additional, O'Neil, Christopher F., additional, Saberi, Rebecca A., additional, Gilna, Gareth P., additional, Lyons, Nicole B., additional, Collie, Brianna L., additional, Parreco, Joshua P., additional, Thorson, Chad M., additional, Sola, Juan E., additional, and Perez, Eduardo A., additional

Published
2023
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36. Penetrating Abdominal Trauma from Liposuction: The Miami Experience

Author

Lyons, Nicole B., primary, Ramsey, Walter A., additional, Cohen, Brianna L., additional, O’Neil, Christopher F., additional, Botero-Fonnegra, Cristina, additional, Huerta, Carlos T., additional, Arakelians, Aris, additional, Jabori, Sinan, additional, Proctor, Kenneth G., additional, Kassira, Wrood, additional, Kaufman, Joyce I., additional, Lineen, Edward B., additional, Singh, Devinder, additional, and Namias, Nicholas, additional

Published
2023
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39. Expert Consensus for Key Features of Operative Reports of Ventral Hernia

Author

Dhanani, Naila H, primary, Lyons, Nicole B, additional, Divino, Celia M, additional, Harris, Hobart, additional, Holihan, Julie L, additional, Hope, William, additional, Itani, Kamal, additional, Loor, Michele M, additional, Martindale, Robert, additional, Prabhu, Ajita, additional, Reinke, Caroline, additional, Roth, J Scott, additional, Towfigh, Shirin, additional, and Liang, Mike K, additional

Published
2022
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40. Statistical Power of Randomized Controlled Trials in Trauma Surgery.

Author

Berg, Arthur, Lyons, Nicole B., Badami, Abbasali, Reynolds, John, Pizano, Louis, Pust, Gerd Daniel, Meizoso, Jonathan, Namias, Nicholas, and Yeh, Daniel Dante

Subjects
*TRAUMA surgery, *STATISTICAL power analysis, *STATISTICS, *BIBLIOMETRICS, *RANDOMIZED controlled trials, *DESCRIPTIVE statistics, *DATA analysis, *DATA analysis software, *ODDS ratio
Abstract

BACKGROUND: Our purpose was to conduct a bibliometric study investigating the prevalence of underpowered randomized controlled trials (RCTs) in trauma surgery. STUDY DESIGN: A medical librarian conducted a search of RCTs in trauma published from 2000 to 2021. Data extracted included study type, sample size calculation, and power analyses. Post hoc calculations were performed using a power of 80% and an alpha level of 0.05. A CONSORT checklist was then tabulated from each study as well as a fragility index for studies with statistical significance. RESULTS: In total 187 RCTs from multiple continents and 60 journals were examined. A total of 133 (71%) were found to have "positive" findings consistent with their hypothesis. When evaluating their methods, 51.3% of articles did not report how they calculated their intended sample size. Of those that did, 25 (27%) did not meet their target enrollment. When examining post hoc power, 46%, 57%, and 65% were adequately powered to detect small, medium, and large effect sizes, respectively. Only 11% of RCTs had complete adherence with CONSORT reporting guidelines and the average CONSORT score was 19 out of 25. For positive superiority trials with binary outcomes, the fragility index median (interquartile range) was 2 (2 to 8). CONCLUSIONS: A concerningly large proportion of recently published RCTs in trauma surgery do not report a priori sample size calculations, do not meet enrollment targets, and are not adequately powered to detect even large effect sizes. There exists opportunity for improvement of trauma surgery study design, conduct, and reporting. [ABSTRACT FROM AUTHOR]

Published
2023
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43. Expert Consensus for Key Features of Operative Reports of Ventral Hernia.

Author

Dhanani, Naila H., Lyons, Nicole B., Divino, Celia M., Harris, Hobart, Holihan, Julie L., Hope, William, Itani, Kamal, Loor, Michele M., Martindale, Robert, Prabhu, Ajita, Reinke, Caroline, Scott Roth, J., Towfigh, Shirin, and Liang, Mike K.

Subjects
*HERNIA surgery, *DOCUMENTATION, *QUESTIONNAIRES, *DESCRIPTIVE statistics, *DELPHI method
Abstract

BACKGROUND: Operative reports are important documents; however, standards for critical elements of operative reports are general and often vague. Hernia surgery is one of the most common procedures performed by general surgeons, so the aim of this project was to develop a Delphi consensus on critical elements of a ventral hernia repair operative report. STUDY DESIGN: The Delphi method was used to establish consensus on key features of operative reports for ventral hernia repair. An expert panel was selected and questionnaires were distributed. The first round of voting was open-ended to allow participants to recommend what details should be included. For the second round the questionnaire was distributed with the items that did not have unanimous responses along with free text comments from the first round. RESULTS: Eighteen surgeons were approached, of which 11 completed both rounds. Twenty items were on the initial questionnaire, of which 11 had 100% agreement. Of the remaining 9 items, after the second questionnaire an additional 7 reached consensus. CONCLUSION: Ventral hernia repairs are a common and challenging problem and often require reoperations. Surgeons frequently refer to previous operative notes to guide future procedures, which requires detailed and comprehensive operative reports. This Delphi consensus was able to identify key components needed for an operative report describing ventral hernia repair. [ABSTRACT FROM AUTHOR]

Published
2023
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47. 2019 Health Equity Summer Research Summit Organized by the Center of Excellence in Health Equity, Training and Research, Baylor College of Medicine, Houston, Texas 77030, USA on June 18th, 2019

Author

Uribe-Gomez, A, primary, Salinas-Miranda, Abraham A., additional, Turner, Acara E., additional, Strutt, Adriana M., additional, Joseph, Adrienne, additional, Wright, Alex, additional, Martin, Alexander C., additional, Milton, Alexis N., additional, Khoei, Amelia, additional, Kanakamedala, Amritha, additional, Iyinbor, Angie, additional, O, Anna, additional, Morrow, Asha, additional, Butler, Ashley M., additional, Young, Ashley, additional, Shah, Asim, additional, Matin, Asna, additional, Christiansen, Audrey E., additional, Ibrahimou, Boubakari, additional, Alonzo, Breanna, additional, Ossenkop, Chase, additional, O, Carli, additional, Hsu, Chih-Wei, additional, Ikeanyionwu, Charles, additional, Anyanwu, Chinwe, additional, Rivas, Charlotte, additional, Ikedionwu, Chioma A., additional, Anugwom, Chioma, additional, Broda, Christopher R., additional, Bocchini, Claire, additional, Cummins, Claire, additional, Rooney, Cliona M., additional, Keo-Meier, Colton L., additional, Johnson, Connor, additional, Miller-Chism, Courtney, additional, Titus, Courtney, additional, Parker, Crystal L., additional, Bird, Cylaina, additional, Mauck, Daniel, additional, Persse, David, additional, Austin, Deborah A., additional, Dongarwar, Deepa, additional, Cherla, Deepa V., additional, Wolf, Dwayne, additional, Schwartz, Eleanor Bimla, additional, Petrova, Elena, additional, Perli, Elias, additional, Shell, Elisabeth, additional, Tran, Elizabeth U., additional, Baena, Elsa, additional, Lopez, Elyse, additional, Berry, Estrellita, additional, Rodriguez, Evadne, additional, Faustinella, Fabrizia, additional, Ihekweazu, Faith D., additional, Jiwani, Faiz, additional, Chmaitelli, Gabriella P., additional, Chan, Galant, additional, Wang, Haijun, additional, Salihu, Hamisu M., additional, Combs, Hannah L., additional, Rogers, Hayley, additional, Haq, Heather, additional, Sosa, Iberia Romina, additional, Jose, Irene E., additional, Griffin, Isabel, additional, Cao, J., additional, Montealegre, Jane, additional, Salemi, Jason L., additional, Chang, Jennifer, additional, Stinson, Jennifer M., additional, Mills, JL, additional, Schulte, Joann, additional, Thomas, Joel, additional, Prochaska, John, additional, Saunders, John, additional, Go, Jonathan, additional, Lim, Jonathan, additional, Salley, Jordan, additional, Pineda, Josue Estiven, additional, Tabilona, Jules, additional, Holihan, Julie L., additional, Bowen-Jallow, Kanika, additional, Bernardi, Karla, additional, Fredricks, Karla, additional, Salciccioli, Katherine B., additional, Lopez, Keila N., additional, Barning, Kenneth, additional, Vuong, Kevin Dat, additional, Yusuf, Korede K., additional, Myers, Kristopher, additional, Wilson, Kyle, additional, Laufman, Larry E., additional, Love, Latanya J., additional, Nolan, Lauren, additional, Schoen, Lauren, additional, Huang, Lillian, additional, King, Lindsey M., additional, Nunez, Lisa F., additional, Brown, Louis, additional, Hernandez, Luna, additional, Hydod, Lynn, additional, Rossetti, M. Agustina, additional, Allman, Madeleine, additional, Khan, Mahmood, additional, Marty, Makenna, additional, Lee, MaKenzie D., additional, Jaramillo, Maria A., additional, Vigil, Maria, additional, Boyle, Mariaelena, additional, Masciale, Marina, additional, Hilliard, Marisa, additional, Munoz, Marisela, additional, Dickinson, Mary E., additional, Bell, Meishon, additional, York, Michele K., additional, Loor, Michelle, additional, Lopez, Michelle, additional, Liang, Mike K., additional, Aziz, Moez Karim, additional, Karla, Moriel, additional, Osazuma, Nancy, additional, Ramirez, Natalya, additional, Navejar, Natasha, additional, Cort, Nicol, additional, Lyons, Nicole B., additional, Perez, Norma, additional, Barshes, NR, additional, Barron, Olivia A., additional, Olavarria, Oscar A., additional, Constable, Petra, additional, Nwokolo, Phyllis, additional, Omokaro, Precious, additional, Patel, Premal, additional, Vallabh, Prithvi, additional, Shah, Puja, additional, Yusuf, Rafeek A., additional, Rosero, Rebecca A., additional, Lunstroth, Rebecca, additional, Obure, Renice, additional, Beach, Robert, additional, Goin-Kochel, Robin, additional, Parihar, Robin, additional, Zoorob, Roger, additional, Wilson, Ronee E., additional, Schmidt, Rosa Michelle, additional, Pettit, Rowland, additional, Udoetuk, Sade C., additional, Tasnim, Sadia, additional, Khan, Sara, additional, Adnan, Sareema, additional, Rodriguez, Sean, additional, Anandasabapathy, Sharmila, additional, Nesbitt, Shawna, additional, Bhushan, Sheena, additional, Sharath, Sherene, additional, Rogers, SO, additional, Dinh, Son, additional, Banu, Sophia, additional, Rose, Stacey, additional, Drake, Stacy, additional, Morain, Stephanie, additional, McCauley, Stephen R., additional, Abdelaziz, Sue, additional, Malik, Tahir, additional, Rasmussen, Tara L., additional, Shum, Thomas, additional, Raphel, Tiana, additional, Ko, Tien C., additional, Harris, Toi, additional, Hadley, Trevor, additional, Akoma, Uchechukwu, additional, Eduok, Uwem Bridgette, additional, Armendariz, Victoria, additional, Cole-Lewis, Yasmin C., additional, Al-Mohtaseb, Zaina, additional, and Yusuf, Zenab, additional

Published
2020
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48. Gender Disparity in Surgery: An Evaluation of Surgical Societies

Author

Lyons, Nicole B., primary, Bernardi, Karla, additional, Huang, Lillian, additional, Holihan, Julie L., additional, Cherla, Deepa, additional, Martin, Alexander C., additional, Milton, Alexis, additional, Loor, Michele, additional, Ko, Tien C., additional, Liang, Mike K., additional, and Hydo, Lynn, additional

Published
2019
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50. Are online surgical discussion boards a safe and useful venue for surgeons to ask for advice? A review of the International Hernia Collaboration Facebook Group.

Author

Bernardi, Karla, Milton, Alexis N., Hope, William, Roth, John Scott, Shah, Shinil K., Shah, Puja, Lyons, Nicole B., Martin, Alexander C., Holihan, Julie L., Cherla, Deepa V., Ko, Tien C., Hughes, Tyler G., Liang, Mike K., and Social Media in Surgery and Medicine Study Group

Subjects
HERNIA, INTERNET forums, ADVICE, SURGEONS, EVIDENCE-based management
Abstract

Background: Social media is a growing medium for disseminating information among surgeons. The International Hernia Collaboration Facebook Group (IHC) is a widely utilized social media platform to share ideas and advice on managing patients with hernia-related diseases. Our objective was to assess the safety and utility of advice provided.Methods: Overall, 60 consecutive de-identified clinical threads were extracted from the IHC in reverse chronological order. A group of three hernia specialists evaluated all threads for unsafe posts, unhelpful comments, and if an established evidence-based management strategy was provided. Positive and negative controls for safe and unsafe answers were included in seven threads and reviewers were blinded to their presence. Reviewers were free to access all online and professional resources (except the IHC).Results: There were 598 unique responses (median 10, 1-26 responses per thread) to the 60 clinical threads/scenarios. The review team correctly identified all seven positive and negative controls. Most responses were safe (96.6%) but some were unhelpful (28.4%). For sixteen threads, the reviewers believed there was an established evidence-based answer; however, only six were provided. In addition, 14 responses were considered unsafe, but only four were corrected.Conclusions: The vast majority of responses were considered helpful; however, evidence-based management is typically not provided and unsafe recommendations often go uncontested. While the IHC allows wide dissemination of hernia-related surgical advice/discussions, surgeons should be cautious when using the IHC for clinical advice. Mechanisms to provide evidence-based management strategies and to identify unsafe advice are needed to improve quality within online forums and to prevent patient harm. [ABSTRACT FROM AUTHOR]

Published
2020
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