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The aim of this study was to evaluate the superovulation response of Beef and Dairy donor cows to two different follicular emergence synchronization protocols. Twenty-two beef and dairy cows were divided into two groups viz. Conventional group (n=8) having four Holsteins and four Charolais cows between days 10 and 11 of their estrous cycle and IVD+EB group (n=14) with six Holsteins and eight Charolais cows treated with an intravaginal device (IVD) containing 1.9 g of P4 + 2 mg of estradiol benzoate (EB) between days 10 and 11 of their estrous cycle. The superovulation protocol consisted of intramuscular application of FSHp twice a day for four days, in decreasing doses (850 IU for Dairy cows and 500 IU for Beef cows). The number of follicles (13±1.1 vs. 7.5±0.9) and embryos collected (11.7±2.1 vs 6.1±1.0) were significantly affected by the treatment in the Beef cows but, the protocols did not significantly affect these variables in Dairy cows (12.2±0.9 vs 10.4±0.7, respectively). Regarding the production of non-viable embryos, a significant difference was only found in the group of Beef cows for both treatments (8.2±2.3 vs. 1.3±0.3, respectively). Results showed that IVD+EB is not necessary for the superstimulation of the emergence of a new follicular wave before superovulation when it starts in the mid-luteal phase of the estrous cycle in Holstein cows and beef cows, since they had similar results without significant differences between both treatments.

The remanent domain structures of composite element magnetic barcodes have been imaged using photo-emission electron microscopy with contrast from x-ray magnetic circular dichroism (XMCD-PEEM) and analysed with reference to the results of micromagnetic simulations. The magnetisation configuration at the end of wide strips is found to be perpendicular to the majority magnetisation direction. This transitions to an incomplete rotation for nominal strip widths below 300 nm and is found to affect the mechanics of magnetisation reversal for nominal strip widths below 200 nm, owing to a difference in magnetisation orientation when an external magnetic field is applied that is just smaller than the magnetic coercivity of the structures and a corresponding change in reversal dynamics. This change in domain structure as strip width decreases is consistent with both the influence of shape anisotropy and with measurements of magnetic hysteresis. The magnetisation reversal characteristics of composite element structures are found to be dependent on the relative magnetisation configurations of neighbouring strips, which in turn are found to vary stochastically upon the application and removal of a magnetic field along the easy axis of the structure. It is found that the application of a canted field is necessary to ensure sharp, consistent magnetisation reversal of bits when writing a binary code. These results confirm that either improved lithography of narrower strips or non-rectangular elements would be necessary to further increase the number of individually programmable bits in a barcode.

El uso de talidomia es controvertido y especialmente en población pediátrica, si bien es cierto las publicaciones disponibles avalan su uso en determinadas condiciones en las que la presencia de aftas bucales comprometa la calidad de vida de los pacientes y éstas no hayan sido resueltas con los tratamientos habituales. En nuestro caso nos encontramos ante una paciente pediátrica donde la estomatitis aftosa condicionaba incluso su correcta alimentación, por este motivo y tras realizar las pruebas oportunas para determinar las causas de las mismas se decide comenzar el tratamiento con talidomida. Los resultados fueron muy positivos en cuanto a reducción de episodios aftosos pero los efectos adversos observados en la paciente condicionaron la suspensión del tratamiento. La implicación farmacéutica hizo posible una coordinación entre atención primaria y especializada, un asesoramiento tanto a personal sanitario como a la paciente y tutores legales, la adquisición del fármaco y la elaboración de una fórmula magistral adaptada a los cambios posológicos. Por otro lado el estrecho seguimiento de la paciente y de los efectos adversos hizo posible su suspensión en el momento en el que la relación beneficio/riesgo ya no era favorable.

It is well known that road safety is a major problem in cities, resulting in a large number of accidents with significant injuries and loss of life. Much of this problem occurs when vehicles interact with pedestrians. To try to minimize this problem to a large extent, a combined system using resins and a photoluminescent additive was proposed. To confirm the goodness of this material, a characterisation was carried out covering luminance, vibroacoustic and mechanical properties and a study of its photogrammetry under real conditions of use. A luminance of 68 mcd/m2 at 20 min was confirmed, which would allow, by a wide margin, a pedestrian crossing to be observed in a vehicle more than 100 m away. The acoustic vibration test confirmed that the proposed system would provide a very efficient audible warning to pedestrians and would reduce the average vehicle speed by about 37 % overall, while in cases where vehicles have to stop for pedestrians, this reduction would be about 28 %. With the mechanical characterisation, it was possible to determine a vertical displacement of always less than 2 mm in vehicles with a wheel load of 12.5 kN, reaching a compressive and tensile strength of more than 56 MPa. The results obtained confirm a potential reduction in mortality of close to 110 %, and injuries by approximately 55 %, as a consequence of the reduction in vehicle speed. In addition, improved night-time visibility of pedestrian crossings would reduce deaths by 35 % and injuries by 26 %, while in the most favourable situations, these values would be 14 % and 10 % for deaths and injuries respectively. All this confirms the great advantage of the system for improving road safety in urban environments.

Se analizaron las macroalgas de fondo duro en 17 sitios de la laguna arrecifal de la Reserva de la Biosfera de Banco Chinchorro. Se registraron 36 especies. Canistrocarpus cervicornis fue la especie dominante. Los intervalos de diversidad estuvieron entre 1,5 a 3,31 bits·ind-1, el área más diversa estuvo en la parte sur de la laguna donde existía mayor presencia de sustratos coralinos. La similitud de los sitios obtenido con el índice de Morisita, presenta grupos diversos y heterogéneos que tipifican áreas específicas dentro de la laguna arrecifal, principalmente las cercanas a barlovento. El análisis canónico muestra la dependencia de los sitios hacia los factores ambientales; sin embargo, la salinidad y la temperatura de la superficie son restrictivas para las algas del fondo duro. Se presenta una alta correlación mayor de 0,9 entre los parámetros ambientales y los tres primeros componentes principales del sistema.

Introduction Schizophreniform Disorder is described pretty similar to schizophrenia, but with the difference of the symptoms duration which have to last for at least 1 month but less than 6 months. Patients have to be back at their baseline functional level once the disorder has resolved. This is a heterogeneous group of patients who have either a disorder similar to schizophrenia or something closer to a mood disorder. Objectives To analyze clinical, psychopathological and epidemiological characteristics of schizophreniform disorder and also review causes, incidence, prevalence, diagnostic, therapeutic tools and the importance of maintaining the treatment, because of the abandonment of the treatment, which is a predictor of relapses. Methods A review of the main impact literature concerning schizophreniform disorder is done during the last five years: prevalence, incidence, pathogenesis and its relationship with other psychiatric disorders encoded in DSM-V are studied. Results The etiology is unknown. Psychotic symptoms can be treated with antipsychotics for 3 to 6 months. They usually respond faster than patients with schizophrenia (75% vs 20% respond within 8 days). Conclusions The disease has a favorable prognosis, and has similarities with mood disorders. However, some data suggest a close relationship to schizophrenia. In support of the relationship with mood disorders, patients have more affective symptoms and a better outcome than patients with schizophrenia. Disclosure of Interest None Declared

Introduction Significant and measurable cognitive symptoms are present at the onset of the disorder and these remain stable in the subsequent period between 2 and 5 years. Their deterioration increases with the course of the disease. Attention, concentration, psychomotor speed and resolution of conceptual tasks are usually affected and are more significant in the presence of positive symptoms. Objectives Sometimes, the typical positive or negative symptoms of the disease do not adequately reflect the severity of cognitive impairment. Measuring this deterioration can be very relevant when evaluating the severity and the prognosis of the disorder. Methods 31-year-old male with a previous diagnosis of schizophrenia of 4 years of evolution. He gets a maintained treatment with amisulpiride 400mg with an apparent good response. A single hospitalization at the onset of the disease. An assassination attempt on his mother is done by suffocation with a pillow and observing a significant cognitive impairment despite an apparent control of the symptoms of schizophrenia. Results An exhaustive neuropsychological evaluation is carried out, observing a very important cognitive deterioration that had not been previously detected and allowing a pharmacological adjustment of the underlying disease with global improvement of the patient. Conclusions It is very important to evaluate the patient as a whole without forgetting the frequent cognitive damage that these patients can have. An intense neuropsychological study can be very useful to evaluate the prognosis and adequate treatment of the patient in order to reduce serious risks. Disclosure of Interest None Declared

Identifying novel risk-resilient diets is urgent to address food insecurity and tackle global hunger and malnutrition. This study evaluated the suitability of mesquite (Neltuma spp.) pod flours as food staples for human nourishment and compared nutritional properties of mesquites growing natively or as introduced species in the drylands of Mexico, Kenya and Tanzania. Using gas chromatography and mass spectrometry, we analysed chemical composition, dietary fibre, antinutrients, amino acids and fatty acids of pod flours from Neltuma laevigata, N. laevigata × N. odorata and N. velutina (abundant native species of Northern Mexico). We also studied the introduced N. juliflora from Kenya, and N. pallida from Tanzania which have become invasive. This research demonstrates that mesquite flour contains all the essential amino acids, with the highest being valine, leucine and lysine. The most abundant non-essential amino acids are aspartate, glutamate and proline. Mesquite flours are rich in palmitic, oleic and linolenic acids. Besides this, mesquite flour is abundant in phenols and contains less gallic and phytic acids than wheat. We show that nutritionally, mesquite flours are comparable to wheat flour. These findings demonstrate that Neltuma pod flours are excellent candidates to reduce malnutrition and hunger for the poorest people of the world.

Introduction ADHD is a diagnosis almost always made in childhood or adolescence and oftent difficult to make it new in adults because it is not thought of in the differential diagnosis process and for the lack of experience from adult devices. - ADHD in adults is characterized by symptoms of executive dysfunction, inattention, emotional dysregulation. The symptoms of impulsivity and hyperactivity tend to be less evident. Objectives - Frequently, the adult patient with ADHD comes to the consultation with a secondary symptom and the primary pathology is hidden and often not evident at first glance. Methods - A 20-year-old woman, university student, with no relevant medical or psychiatric history, without toxic habits, who attended her first consultation referred by her primary care physician for long-standing insomnia, restless legs and anxiety. - The patient’s underlying complaint and her bigger concern is her poor academic performance. It is striking that she has just started her third year at the university, the first year she did not pass any subjects, the second year she changed majors and only passed two, now she is repeating the course. - The examination did not reveal overt affective symptoms, nor psychotic symptoms or other notable psychopathology. The patient’s speech tended towards superficiality, inconcretion, it was salty, it was difficult for her to express herself, even suggesting a certain intellectual disability. - In the first consultation sleep study is requested. And referral to clinical psychology consultation for psychometric study. Results - She is administered Clinical interview and WAIS IV (Adult Intelligence Scale), Trail Making Test, d2 and Stroop, Diagnostic Interview for ADHD in adults (inattention items). - The WAIS-IV demonstrated global cognitive abilities within normality, although with significantly lower scores in the IMT and IVP indices which involve the functions of attention, concentration, mental control and short-term visual memory). Trail Making Test, d2, Stroop and Diagnostic Interview of ADHD in adults (inattention items) yielded profile results highly suggestive of Attention Deficit Disorder without Hyperactivity. - The insomnia subsided with a regimen of 7.5 mg of mirtazapine per day. Subsequently, after starting treatment with low-dose methylphenidate (20 mg/day), the patient improved very significantly, both academic performance and social functioning and mood, self-esteem and subjective well-being. Conclusions - We must always include ADHD in the differential diagnosis of a young adult patient when faced with a wide variety of consultation symptoms, especially if they report some type of deterioration or dysfunction in their social, family or academic life. - An adequate clinical evaluation supported, if possible, by psychometric tests is essential to reach the diagnosis, which allows establishing an effective treatment that modifies the patient’s overall prognosis. Disclosure of Interest None Declared

Not much has been said about Mexican teachers’ teaching practices regarding teamwork in higher education. Ruiz-Esparza Barajas et al. (2016) discussed university teachers’ perceptions of out-of-class teamwork. As part of the second stage of a larger project which attempts to shed light on university teaching practices regarding out-of-class teamwork, this study examines teachers’ practices of out-of-class teamwork from the assessment perspective. Teachers’ approaches to the evaluation of the outcomes of teamwork are a relatively unexplored area, especially in the Latin-American context. This qualitative research study accounts for the teamwork assigned by education or subject-related teachers and their evaluation approaches. Data collected from recorded interviews of twelve teachers working with teachers-to-be in 8 Mexican universities were transcribed to identify their beliefs and practices regarding evaluating out-of-class teamwork. The outcome of the analysis reveals teachers use teamwork for varied reasons and purposes; their expected outcomes are also dissimilar. While some teachers feel satisfied with their approach to evaluating out-of-class teamwork, others feel there is still work to do in this area. It may be suggested that this could be related to their initial purpose in using out-of-class teamwork.

This paper presents an analysis of different despeckling filters applied on both synthetically corrupted optical images and actual Synthetic Aperture Radar (SAR) images. Several authors use optical images as ground truth and then the images are corrupted by using a Gamma model to simulate the speckle, while other approaches use methods like multitemporal fusion to generate a ground truth using actual SAR images, which provides a result somehow equivalent to the one from the common multi look technique. Well-known filters, like local, and non-local and some of them based on artificial intelligence and deep learning, are applied to these two types of images and their performance is assessed by a quantitative analysis. One last validation is performed with a newly proposed method by using ratio images, resulting from the mathematical division (Hadamard division) of filtered and noisy images, to measure how similar the initial and the remaining speckle are by considering its Gamma distribution and divergence measurement. Our findings suggest that despeckling models relying on artificial intelligence exhibit notable efficiency, albeit concurrently displaying inflexibility when applied to particular image types based on the training dataset. Additionally, our experiments underscore the utility of the divergence measurement in ratio images in facilitating both visual inspection and quantitative evaluation of residual speckles within the filtered images.

The High-Altitude Water Cherenkov (HAWC) Gamma-Ray Observatory, located on the side of the Sierra Negra volcano in Mexico, has been fully operational since 2015. The HAWC collaboration has recently significantly improved their extensive air shower reconstruction algorithms, which has notably advanced the observatory performance. The energy resolution for primary gamma rays with energies below 1 TeV was improved by including a noise-suppression algorithm. Corrections have also been made to systematic errors in direction fitting related to the detector and shower plane inclinations, ${ \mathcal O }(0\buildrel{\circ}\over{.} 1)$ biases in highly inclined showers, and enhancements to the core reconstruction. The angular resolution for gamma rays approaching the HAWC array from large zenith angles (>37°) has improved by a factor of 4 at the highest energies (>70 TeV) as compared to previous reconstructions. The inclusion of a lateral distribution function fit to the extensive air shower footprint on the array to separate gamma-ray primaries from cosmic-ray ones based on the resulting χ ^2 values improved the background rejection performance at all inclinations. At large zenith angles, the improvement in significance is a factor of 4 compared to previous HAWC publications. These enhancements have been verified by observing the Crab Nebula, which is an overhead source for the HAWC Observatory. We show that the sensitivity to Crab-like point sources ( E ^−2.63 ) with locations overhead to 30° zenith is comparable to or less than 10% of the Crab Nebula’s flux between 2 and 50 TeV. Thanks to these improvements, HAWC can now detect more sources, including the Galactic center.

HESS J1809-193 is an unidentified TeV source, first detected by the High Energy Stereoscopic System (H.E.S.S.) collaboration. The emission originates in a source-rich region that includes several supernova remnants (SNRs) and pulsars including SNR G11.1+0.1, SNR G11.0-0.0, and the young radio pulsar PSR J1809-1917. Originally classified as a pulsar wind nebula candidate, recent studies show the peak of the TeV region overlapping with a system of molecular clouds. This resulted in the revision of the original leptonic scenario to look for alternate hadronic scenarios. Marked as a potential PeVatron candidate, this region has been studied extensively by H.E.S.S. due to its emission extending up to several tens of TeV. In this work, we use 2398 days of data from the High Altitude Water Cherenkov (HAWC) observatory to carry out a systematic source search of the HESS J1809-193 region. We were able to resolve emission detected as an extended component (modelled as a symmetric Gaussian with a 1 σ radius of 0.°21) with no clear cutoff at high energies and emitting photons up to 210 TeV. We model the multiwavelength observations for the region around HESS J1809-193 using a time-dependent leptonic model and a lepto-hadronic model. Our model indicates that both scenarios could explain the observed data within the region of HESS J1809-193.

México es de los principales productores y exportadores de miel de abejas (Apis mellifera L.) a nivel mundial y el estado de Jalisco se encuentra entre los tres primeros productores a nivel nacional. Sin embargo, la apicultura mexicana es afectada por el alto comportamiento defensivo y menor productividad de las abejas africanizadas en comparación con abejas europeas. El objetivo de este estudio fue determinar la ancestría africana o europea de colonias de abejas melíferas en seis regiones de clima templado y subtropical en el estado de Jalisco, México, mediante análisis morfométricos y de ADN mitocondrial. Más del 50% de las colonias de abejas de Jalisco tuvieron mitotipo y morfotipo africano (59.0 y 62.5%, respectivamente). La frecuencia de africanización de las colonias fue significativamente mayor (p < 0.05) en regiones de baja altitud y climas subtropicales (regiones Sureste y Suroeste), que en regiones de mayor elevación y en climas templados (región de los Altos). Hubo correlación significativa entre la longitud del ala de las abejas y la altitud a la que se encontraban las colonias (r = 0.51, p < 0.01); esto indica que a menor altitud hay un mayor grado de africanización de las abejas. Se recomiendan realizar estudios para determinar si el grado de africanización de las colonias de abejas aumenta o se mantiene en equilibrio, lo que permitirá diseñar estrategias de amortiguamiento de los efectos negativos de la africanización de las abejas melíferas.

Radar interferometry has progressed very much in the last two decades. It is now a powerful remote sensing techniques to monitor ground motion. The technique has undergone an important development in terms of processing and data analysis algorithms. This has been accompanied by an important increase of the Synthetic Aperture Radar (SAR) data acquisition capability by spaceborne sensors. A step forward was the launch of the Copernicus Sentinel-1 constellation. This has made the development of A-DInSAR (Advanced Differential Interferometric SAR) ground deformation services technically feasible. The paper is focused on the most important ground motion initiative ever conceived: the European Ground Motion Service (EGMS). This service is part of the Copernicus Land Monitoring Service managed by the European Environment Agency. EGMS involves the ground deformation monitoring at European scale. The service will deliver the first product in May 2022. In this paper we describe some preliminary examples of deformation products coming from the EGMS.