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Abstract We present the first global analysis of generalized parton distributions (GPDs) combing lattice quantum chromodynamics (QCD) calculations and experiment measurements including global parton distribution functions (PDFs), form factors (FFs) and deeply virtual Compton scattering (DVCS) measurements. Following the previous work where we parameterize GPDs in terms of their moments, we extend the framework to allow for the global analysis at non-zero skewness. Together with the constraints at zero skewness, we fit GPDs to global DVCS measurements from both the recent JLab and the earlier Hadron-Electron Ring Accelerator (HERA) experiments with two active quark flavors and leading order QCD evolution. With certain choices of empirical constraints, both sea and valence quark distributions are extracted with the combined inputs, and we present the quark distributions in the proton correspondingly. We also discuss how to extend the framework to accommodate more off-forward constraints beyond the small ξ expansion, especially the lattice calculated GPDs.

Abstract We study the small-x asymptotics of the flavor non-singlet T-odd leading-twist quark transverse momentum dependent parton distributions (TMDs), the Sivers and Boer-Mulders functions. While the leading eikonal small-x asymptotics of the quark Sivers function is given by the spin-dependent odderon [1, 2], we are interested in revisiting the sub-eikonal correction considered by us earlier in [3]. We first simplify the expressions for both TMDs at small Bjorken x and then construct small-x evolution equations for the resulting operators in the large-N c limit, with N c the number of quark colors. For both TMDs, the evolution equations resum all powers of the double-logarithmic parameter α s ln2(1/x), where α s is the strong coupling constant, which is assumed to be small. Solving these evolution equations numerically (for the Sivers function) and analytically (for the Boer-Mulders function) we arrive at the following leading small-x asymptotics of these TMDs at large N c : f 1 T ⊥ NS x ≪ 1 k T 2 = C O x k T 2 1 x + C 1 x k T 2 1 x 3.4 α s N c 4 π h 1 ⊥ NS x ≪ 1 k T 2 = C x k T 2 1 x − 1 . $$ {\displaystyle \begin{array}{l}{f}_{1T}^{\perp NS}\left(x\ll 1,{k}_T^2\right)={C}_O\left(x,{k}_T^2\right)\frac{1}{x}+{C}_1\left(x,{k}_T^2\right){\left(\frac{1}{x}\right)}^{3.4\sqrt{\frac{\alpha_s{N}_c}{4\pi }}}\\ {}{h}_1^{\perp \textrm{NS}}\left(x\ll 1,{k}_T^2\right)=C\left(x,{k}_T^2\right){\left(\frac{1}{x}\right)}^{-1}.\end{array}} $$ The functions C O (x, k T 2 $$ {k}_T^2 $$ ), C 1(x, k T 2 $$ {k}_T^2 $$ ), and C(x, k T 2 $$ {k}_T^2 $$ ) can be readily obtained in our formalism: they are mildly x-dependent and do not strongly affect the power-of-x asymptotics shown above. The function C O , along with the 1/x factor, arises from the odderon exchange. For the sub-eikonal contribution to the quark Sivers function (the term with C 1), our result shown above supersedes the one obtained in [3] due to the new contributions identified recently in [4].

Abstract We apply the formalism developed earlier [1, 2] for studying transverse momentum dependent parton distribution functions (TMDs) at small Bjorken x to construct the small-x asymptotics of the quark Sivers function. First, we explicitly construct the complete fundamental “polarized Wilson line” operator to sub-sub-eikonal order: this object can be used to study a variety of quark TMDs at small x. We then express the quark Sivers function in terms of dipole scattering amplitudes containing various components of the “polarized Wilson line” and show that the dominant (eikonal) term which contributes to the quark Sivers function at small x is the spin-dependent odderon, confirming the re- cent results of Dong, Zheng and Zhou [3]. Our conclusion is also similar to the case of the gluon Sivers function derived by Boer, Echevarria, Mulders and Zhou [4] (see also [5]). We also analyze the sub-eikonal corrections to the quark Sivers function using the constructed “polarized Wilson line” operator. We derive new small-x evolution equations re-summing double-logarithmic powers of α s ln2(1/x) with α s the strong coupling constant. We solve the corresponding novel evolution equations in the large-N c limit, obtaining a sub-eikonal correction to the spin-dependent odderon contribution. We conclude that the quark Sivers function at small x receives contributions from two terms and is given by f 1 T ⊥ q x k T 2 = C O x k T 2 1 x + C 1 k T 2 1 x 0 + ⋯ $$ {f}_{1T}^{\perp q}\left(x,{k}_T^2\right)={C}_O\left(x,{k}_T^2\right)\frac{1}{x}+{C}_1\left({k}_T^2\right){\left(\frac{1}{x}\right)}^0+\cdots $$ with the function C O (x, k T 2 $$ {k}_T^2 $$ ) varying slowly with x and the ellipsis denoting the subasymptotic and sub-sub-eikonal (order-x) corrections.

ABSTRACT UV light, more specifically UV-C light at a wavelength of 254 nm, is often used to disinfect surfaces, air, and liquids. In early 2020, at the cusp of the COVID-19 pandemic, UV light was identified as an efficient means of eliminating coronaviruses; however, the variability in published sensitivity data is evidence of the need for experimental rigor to accurately quantify the effectiveness of this technique. In the current study, reliable and reproducible UV techniques have been adopted, including accurate measurement of light intensity, consideration of fluid UV absorbance, and confirmation of uniform dose delivery, including dose verification using an established biological target (T1UV bacteriophage) and a resistant recombinant virus (baculovirus). The experimental results establish the UV sensitivity of SARS-CoV-2, HCoV-229E, HCoV-OC43, and mouse hepatitis virus (MHV) and highlight the potential for surrogate viruses for disinfection studies. All four coronaviruses were found to be easily inactivated by 254 nm irradiation, with UV sensitivities of 1.7, 1.8, 1.7, and 1.2 mJ/cm2/log10 reduction for SARS-CoV-2, HCoV-229E, HCoV-OC43, and MHV, respectively. Similar UV sensitivities for these species demonstrate the capacity for HCoV-OC43, HCoV-229E, and MHV to be considered surrogates for SARS-CoV-2 in UV-inactivation studies, greatly reducing hazards and simplifying procedures for future experimental studies. IMPORTANCE Disinfection of SARS-CoV-2 is of particular importance due to the global COVID-19 pandemic. UV-C irradiation is a compelling disinfection technique because it can be applied to surfaces, air, and water and is commonly used in drinking water and wastewater treatment facilities. UV inactivation depends on the dose received by an organism, regardless of the intensity of the light source or the optical properties of the medium in which it is suspended. The 254 nm irradiation sensitivity was accurately determined using benchmark methodology and a collimated beam apparatus for four coronaviruses (SARS-CoV-2, HCoV-229E, HCoV-OC43, and MHV), a surrogate indicator organism (T1UV), and a resistant recombinant virus (baculovirus vector). Considering the light distribution across the sample surface, the attenuation of light intensity with fluid depth, the optical absorbance of the fluid, and the sample uniformity due to mixing enable accurate measurement of the fundamental inactivation kinetics and UV sensitivity.

Abstract The Compact Linear Collider (CLIC) is a proposed future high-luminosity linear electron-positron collider operating at three energy stages, with nominal centre-of-mass energies s $$ \sqrt{s} $$ = 380 GeV, 1.5 TeV, and 3 TeV. Its aim is to explore the energy frontier, providing sensitivity to physics beyond the Standard Model (BSM) and precision measurements of Standard Model processes with an emphasis on Higgs boson and top-quark physics. The opportunities for top-quark physics at CLIC are discussed in this paper. The initial stage of operation focuses on top-quark pair production measurements, as well as the search for rare flavour-changing neutral current (FCNC) top-quark decays. It also includes a top-quark pair production threshold scan around 350 GeV which provides a precise measurement of the top-quark mass in a well-defined theoretical framework. At the higher-energy stages, studies are made of top-quark pairs produced in association with other particles. A study of t̄tH production including the extraction of the top Yukawa coupling is presented as well as a study of vector boson fusion (VBF) production, which gives direct access to high-energy electroweak interactions. Operation above 1 TeV leads to more highly collimated jet environments where dedicated methods are used to analyse the jet constituents. These techniques enable studies of the top-quark pair production, and hence the sensitivity to BSM physics, to be extended to higher energies. This paper also includes phenomenological interpretations that may be performed using the results from the extensive top-quark physics programme at CLIC.

The Vasi peatland complex is situated in the northeast of South Africa. It is an unprotected area surrounded by pine (Pinus sp.) and blue gum (Eucalyptus sp.) plantations. Little is known about the conditioning factors for the area’s development and causes of degradation. In order to understand the ecohydrological system of this complex, water tables and ionic composition of surface water and groundwater, as well as natural isotopes of oxygen, hydrogen and carbon, were measured. Macrofossils and radiocarbon dating of the peat layer were used to describe the historical environmental conditions. We found that peat accumulation started during the Early Holocene and was initiated by terrestrialisation of inter-dune lakes. Our results also show that the Vasi peatland complex is primarily dependent on a perched water table due to the presence of iron-rich deposits close to the surface (i.e. KwaMbonambi Formation). The Vasi peatland basins appear to be hydrologically connected and some basins show indications of cascading through-flow systems, which means that the water flows from a higher basin to a lower one through the permeable parts of the sand dunes and peat layers. The stratigraphy indicates continuous peat accumulation, and thus that the water table was perennially high for thousands of years, despite evidence of the occasional natural occurrence of fires. We conclude that the most likely cause of the observed signs of degradation is land use change, i.e. the recent establishment of plantations, which affect the groundwater system.

South Africa has a limited number of peatlands and most of them are relatively small compared to those in cooler temperate regions in the northern hemisphere. We gathered 40 basal peat samples representative of South Africa’s peatlands to explore their development during the Late Pleistocene and Holocene. Depth profiles of nine of them were also investigated using radiocarbon dating, which yielded information on past environmental changes affecting South African peatlands. The data showed three peaks in the frequency of peatland initiation, which are consistent with available climatic and sea level fluctuation data: one after the Last Glacial Maximum (LGM) and two during the Mid to Late Holocene. Inland peatlands in mountain valleys showed optimal growing conditions during the glacial-interglacial transition, continuing until the Early-Holocene. This is due to the switch to the wet and warm interglacial climate. In contrast, coastal peatlands showed optimal initiation conditions over two phases during the Holocene, which is consistent with sea level rise peaks that led to optimal moist conditions occurring ca. 6,000–3,000 and 1,000 years ago. Sea level rise reduced groundwater drainage, which led to a rise in the primary groundwater table. However, data from some of the coastal peatlands indicate independence from the sea level fluctuation, and that they are rather controlled by climatic conditions and their local hydrogeomorphic setting, e.g. perched groundwater aquifers. Some peatland complexes show a pattern of phased initiation with peat initiation consistent with altitude difference, which could be due to a positive feedback of blocking caused by peat accumulation in lower reaches, reducing groundwater drainage to the sea.

We present the calculation of the leading contribution to the quark Sivers function at small-Bjorken $x$. This calculation uses the high energy scattering approximation and operator formalism developed by Kovchegov and Sievert to obtain a dominant contribution to the quark Sivers function coming from the spin-dependent odderon, in agreement with the results of Dong, Zhen, and Zhou. We then calculate this dominant contribution in the diquark model of the proton to obtain a small-$x$ estimate for the Sivers function.

The physical and hydrological properties of peat from seven peatlands in northern Maputaland (South Africa) were investigated and related to the degradation processes of peatlands in different hydrogeomorphic settings. The selected peatlands are representative of typical hydrogeomorphic settings and different stages of human modification from natural to severely degraded. Nineteen transects (141 soil corings in total) were examined in order to describe peat properties typical of the distinct hydrogeomorphic settings. We studied degree of decomposition, organic matter content, bulk density, water retention, saturated hydraulic conductivity and hydrophobicity of the peats. From these properties we derived pore size distribution, unsaturated hydraulic conductivity and maximum capillary rise. We found that, after drainage, degradation advances faster in peatlands containing wood peat than in peatlands containing radicell peat. Eucalyptus plantations in catchment areas are especially threatening to peatlands in seeps, interdune depressions and unchannelled valley bottoms. All peatlands and their recharge areas require wise management, especially valley-bottom peatlands with swamp forest vegetation. Blocking drainage ditches is indispensable as a first step towards achieving the restoration of drained peatland areas, and further measures may be necessary to enhance the distribution of water. The sensitive swamp forest ecosystems should be given conservation priority.

Abstract Background Medicinal properties of the food species are one of the poorly documented and important areas of ethnopharmacology. The present survey quantitatively documented the medicinal foods prescribed by the non-institutionally trained siddha practitioners of Tiruvallur district of Tamil Nadu. Methods Field work was carried out between December 2014 and April 2017 using a questionnaire. The illnesses mentioned by the informants were grouped as illness categories on the basis of emic perceptions. Sufficiency of sampling of this survey was assessed by plotting the cumulative number of UR and Shannon-Wiener’s index. The indices such as informant consensus factor (FIC), Index of Agreement on Remedies (IAR), and Cultural Food Significance Index (CFSI) were calculated. Results This study documented 165 medicinal foods used by 82 non-institutionally trained siddha practitioners of Tiruvallur district, and 73.93% of these preparations were plant based. Among the animal taxa, 82.05% were represented by fish taxa. The illness category gastrointestinal ailments is the majorly cited illness category treated with plant-based formulations. The illness categories viz., gastrointestinal ailments, hemorrhoids, and neural ailments had high consensus under the group of plant-based medicinal foods. In animal-based medicinal foods, kapha ailments had gained 23.07% of UR. The illness categories such as bone fractures, male reproductive ailments, blood ailments, and anabolic had high FIC values. Conclusions Deeper studies on different dietary cultures of India may help to derive better interpretations on food-medicine continuum. This study identified some important claims such as the use of citron, pomegranate and Solanum americanum (gastrointestinal ailments), Abutilon indicum, onions and elephant foot yam (hemorrhoids), Boerhavia diffusa (urinary ailments), Moringa oleifera (anemia), Aloe vera (gynecological ailments), Eclipta prostrata (liver ailments), ivy gourd (diabetes), citron (hypertension), Centella asiatica (psychological ailments), spade nose shark (lactogogue), reticulate whipray (wheezing and bronchitis), Katelysia opima (impotence), Indian squid (anemia), and Indian oil sardine (anabolic). More studies on these claims will help identify novel functional foods to add to the field of medical nutrition therapy, with traditional brand identity. Robust studies on the documentation of the traditional knowledge on marine resources will yield a good database for various stakeholders and policy makers.

Abstract The Compact Linear Collider (CLIC) is an option for a future $${\mathrm{e}^{+}}{\mathrm{e}^{-}} $$ e + e - collider operating at centre-of-mass energies up to $$3\,\text {TeV} $$ 3 TeV , providing sensitivity to a wide range of new physics phenomena and precision physics measurements at the energy frontier. This paper is the first comprehensive presentation of the Higgs physics reach of CLIC operating at three energy stages: $$\sqrt{s} = 350\,\text {GeV} $$ s = 350 GeV , 1.4 and $$3\,\text {TeV} $$ 3 TeV . The initial stage of operation allows the study of Higgs boson production in Higgsstrahlung ( $${\mathrm{e}^{+}}{\mathrm{e}^{-}} \rightarrow {\mathrm{Z}} {\mathrm{H}} $$ e + e - → Z H ) and $${\mathrm{W}} {\mathrm{W}} $$ W W -fusion ( $${\mathrm{e}^{+}}{\mathrm{e}^{-}} \rightarrow {\mathrm{H}} {{\nu }}_{\!\mathrm{e}} {\bar{{\nu }}}_{\!\mathrm{e}} $$ e + e - → H ν e ν ¯ e ), resulting in precise measurements of the production cross sections, the Higgs total decay width $$\varGamma _{{\mathrm{H}}}$$ Γ H , and model-independent determinations of the Higgs couplings. Operation at $$\sqrt{s} > 1\,\text {TeV} $$ s > 1 TeV provides high-statistics samples of Higgs bosons produced through $${\mathrm{W}} {\mathrm{W}} $$ W W -fusion, enabling tight constraints on the Higgs boson couplings. Studies of the rarer processes $${\mathrm{e}^{+}}{\mathrm{e}^{-}} \rightarrow \mathrm{t} {\bar{\mathrm{t}}} {\mathrm{H}} $$ e + e - → t t ¯ H and $${\mathrm{e}^{+}}{\mathrm{e}^{-}} \rightarrow {\mathrm{H}} {\mathrm{H}} {{\nu }}_{\!\mathrm{e}} {\bar{{\nu }}}_{\!\mathrm{e}} $$ e + e - → H H ν e ν ¯ e allow measurements of the top Yukawa coupling and the Higgs boson self-coupling. This paper presents detailed studies of the precision achievable with Higgs measurements at CLIC and describes the interpretation of these measurements in a global fit.

Salmonella Typhimurium 1,4,[5],12:i:- is a major serovar responsible for human salmonellosis whose biofilm-forming ability, influenced by environmental conditions like those found in the gastrointestinal tract, is one of the main contributing factors to its ability to persist in the host and thus one of the main causes of chronic relapsing infections. Most studies to evaluate biofilm formation are performed in microtiter assays using standard media. However, no reports are available on the ability of this serovar to produce biofilm under in vitro simulated gastrointestinal conditions which better correlate with the environment found in the gastrointestinal tract. To address this, a modified biofilm assay simulating intestinal fluid was conceived to assess the biofilm formation of 133 Salmonella Typhimurium 1,4,[5],12:i:- isolates with and without agitation and at three different time points (24 h, 48 h, and 72 h). The results were then compared to the existing microtiter method using conventional biofilm growth medium (Mueller Hinton Broth). Statistical analysis revealed significant differences in the results obtained between the three protocols used. The simulated human intestinal environment impaired biofilm production demonstrating that conditions like pH, agitation or the presence of enzymes can influence biofilm production. Therefore, results from in vitro simulation of in vivo conditions may contribute to unravelling factors relating to biofilm formation and persistence in the context of the human host.

The present study was carried out to determine the sub lethal toxic effects of the heavy metal cadmium on the electrophoretic protein fractions of gill and muscle tissues of Oreochromis mossambicus. Fishes were exposed to 10% sub lethal concentration (96 h LC50) of cadmium for a period of 10 days. The protein fractions in the muscle of experimental fishes were found to be increased (twelve fractions) with respect to controls (eight fractions). The numbers of protein fractions in the gills of test fishes were found to be lesser than the control fishes. The results of the present study prove that cadmium affects the protein fractions in the tissues of fishes.

Having produced the embryos of cactus Copiapoa tenuissima Ritt. forma monstruosa at the globular stage and callus, we investigated the effect of abscisic acid (ABA) in the following concentrations: 0, 0.1, 1, 10, and 100 μM on successive stages of direct (DSE) and indirect somatic embryogenesis (ISE). In the indirect somatic embryogenesis process we also investigated a combined effect of ABA (0, 0.1, 1 μM) and sucrose (1, 3, 5%). The results showed that a low concentration of ABA (0-1 μM) stimulates the elongation of embryos at the globular stage and the number of correct embryos in direct somatic embryogenesis, while a high ABA concentration (10–100 μM) results in growth inhibition and turgor pressure loss of somatic embryos. The indirect somatic embryogenesis study in this cactus suggests that lower ABA concentrations enhance the increase in calli fresh weight, while a high concentration of 10 μM ABA or more changes calli color and decreases its proliferation rate. However, in the case of indirect somatic embryogenesis, ABA had no effect on the number of somatic embryos and their maturation. Nevertheless, we found a positive effect of sucrose concentration for both the number of somatic embryos and the increase in calli fresh weight.