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Endometrial hyperplastic processes take an important place among the gynecological diseases in women of various ages and are one of the most common reasons for admission at inpatient gynecology departments. The urgency of the pathology is due to the significant prevalence of endometrial hyperplastic processes, high incidence of malignancy, prolonged relapsing course, and decreased reproductive function, since these diseases are one of the most common causes of infertility in women of childbearing age. The statistics related to the incidence of endometrial hyperplastic processes in Ukraine is not available. An analysis of case histories and medical records showed that in 40% of cases, endometrial hyperplastic processes were asymptomatic. In 60% of cases, the clinical manifestations of endometrial hyperplastic processes were menstrual disorders, such as dysmenorrhea, oligomenorrhea, menorrhagia, and metrorrhagia. In 30% of cases, endometrial hyperplastic processes were recurrent. The most common concomitant pathologies of the pelvic organs were uterine leiomyoma and endometriosis; the most common concomitant extragenital diseases were hypertension and obesity. Our study and data analysis showed that there is an increasing trend in the incidence of endometrial hyperplastic processes in Sumy region in 2011–2020. The maximum incidence was in 2016. A correlation was found between hyperplasia incidence and age. Thus, the largest number of non-atypical and atypical endometrial hyperplasia cases was observed in women aged 45–55 years. The lowest number of non-atypical endometrial hyperplasia cases was registered in women aged 66+, while atypical hyperplasia cases – in women under 30 years of age. Glandular polyps of the endometrium were most often diagnosed at the age of 31–44; the lowest number of these was found in women over 66 years. Most glandular-fibrous endometrial polyps were observed in women aged 45–55 years, while women under 30 presented with the fewest cases. Fibrous endometrial polyps were most common in older age groups – 66+; the lowest number of such endometrial polyps was found in women under 30 years. We attributed the decreased incidence of endometrial hyperplastic processes in 2020 to the quarantine measures introduced, which, as a consequence, led to the decreased number of diagnosed cases, since they are often asymptomatic.

A recurrence algorithm for finding particular solutions of the resonant equation of the fourth order connected with the generalization of Laguerre and Legendre polynomials is constructed and substantiated. For this purpose, we use the general theorem on the representation of particular solutions of resonant equations in Banach spaces proved by Makarov in 1976. An example of the general solution of resonant equations with differential operator for the Laguerre-type polynomials is presented.

У статті прорецензовано монографію, у якій автор, використовуючи насамперед польську історіографію, а також напрацювання сучасних українських істориків, на основі широкої джерельної бази робить аналіз української історії першої половини минулого століття істориками Польщі. На підставі цього визначено оригінальність дослідження, авторську концепцію бачення проблеми і практичну значимість наукової роботи.

За результатами аналізу вітчизняного й зарубіжного досвіду оборонного планування та з урахуванням потреб реформування сектору безпеки і оборони України наведено погляди на особливості оборонного планування на основі спроможностей та перспективи його впровадження у процес розвитку сил оборони держави., Based on the analysis of international experience in defence planning and requirements of ongoing reforms in security and defence sector of Ukraine, the article presents an insight on peculiarities of capability-based defence planning and prospects for its implementation in the process of the defence forces development.

The expediency of conducting research and experimental work at the stage of identifying opportunities to improve the educational process in training future public health professionals on the basis of interdisciplinary integration is substantiated. The article is devoted to the role of experimental pedagogical research as a means of testing the effectiveness of interdisciplinary integration in the training of future public health professionals. It is generalized that the issue of professional training of future specialists in the specialty «Public Health» in the pedagogical literature is considered as a component of professional self-determination and professional development in the context of the study of professional self-awareness. It is proved that the interdisciplinary integration in the training of future public health professionals is an integrated component that combines individual and personal features (awareness of the choice of profession, completeness and strength of knowledge in the chosen profession, the formation of professionally significant and empathetic qualities). It is socially oriented and oriented at building relationships and positioning oneself in the team, develops the ability to make decisions independently and take responsibility as well as personality characteristics; it implies the presence of strong beliefs in the values of the profession of public health specialist for the design of their own subjective deontological position in the work connected with their specialty. It is substantiated that the professional training of future medical professionals on the basis of interdisciplinary integration involves creating conditions for identifying personal and social experience of students with the profession and the professional community, is a process of mastering normative professional requirements that allow them to adequately perceive medical reality, as well as to develop professionally expedient strategies and tactics, tasks and plans of professional activity, to consciously regulate one’s own behavior within the established professional and normative imperatives. It was found that the professional training of future public health professionals on the basis of interdisciplinary integration is characterized by the presence of future professionals with a set of knowledge that reflects the substantive essence of intellectual, ideological and moral values; the ability to predict and design the process of professional activity taking into account its specifics in interaction with colleagues and patients and is determined by the content of professional medical ethics and deontology, ethical and moral imperatives and professional and ethical ideals and values of public health. The peculiarities of the formation of professional training of future public health specialists on the basis of interdisciplinary integration are studied.

$\gamma p \rightarrow K^+ \Lambda$ differential cross sections and recoil polarisation data from threshold for extremely forward angles are presented. The measurements were performed at the BGOOD experiment at ELSA, utilising the high angular and momentum resolution forward spectrometer for charged particle identification. The data discriminates between conflicting results in the world data set and enable extraction of the cross section as the minimum momentum transfer to the recoiling hyperon is approached., Comment: 12 pages (including a 2 page appendix), 14 figures

The aim: Was following: the improvement of the treatment results of the lower limbs ulcers, caused by the diabetes mellitus by using our technique of the platelet-rich plasma application; the study of the features of the morphological and immunohistochemical changes, and the effect of the growth factors of the platelet-rich plasma on the regeneration and healing of the ulcers.Materials and methods: 38 patients with the trophic ulcers of the lower limbs, caused by diabetes mellitus were involved in the study. To assess the morphological features of the reparative processes before and after the treatment with PRP, the histological and immunohystochemical studies of the biopsy specimen of ulcers were carried out.Results: The total epithelialization of the ulcers in the patients from the main group was achieved on 46.5 day, and in the comparison group - 81.7 day. The light and optical study of the specimen of the main group, using the autologous platelet-rich plasma revealed the elimination of the destructive changes and reduction of the mixed-cellular infiltration compared to the patients from the comparison group. The immunohystochemical study revealed the increase of the growth factors receptors.Conclusions: The usage of the autologous platelet-rich plasma in the treatment of the trophic ulcers results in the rapid regeneration by the decrease of the destructive and inflammatory changes as well as the improvement of the vascularization.

The BGO-OD experiment at the ELSA accelerator facility uses an energy tagged bremsstrahlung photon beam to investigate the excitation structure of the nucleon via meson photoproduction. The setup with a BGO calorimeter surrounding the target and an open dipole spectrometer covering the for ward region is ideally suited for investigating low momentum transfer processes, in particular in strangeness photoproduction. The associated photoproduction of K0S and hyperons is essential to understand the role of K* exchange mech anisms. A cusp-like structure observed in the yp → K0SΣ+ reaction at the K* threshold is described by models including dynamically generated resonances from vector meson-baryon interactions. Such interactions are pre dicted to give a peak like structure in K0SΣ0 photoproduction off the neutron. A very preliminary cross section is determined and compared to the prediction, the results appear to support the model

The BGO-OD experiment at the ELSA accelerator facility uses an energy tagged bremsstrahlung photon beam to investigate the excitation structure of the nucleon. The setup consists of a highly segmented BGO calorimeter surrounding the target, with a particle tracking magnetic spectrometer at forward angles. BGO-OD is ideal for investigating low momentum transfer processes due to the acceptance and high momentum resolution at forward angles. In particular, this enables the investigation of strangeness photoproduction where t-channel exchange mechanisms play an important role. This also allows access to low momentum exchange kinematics where extended, molecular structure may manifest in reaction mechanisms. First key results at low $t$ indicate a cusp-like structure in $K^+\Sigma^0$ photoproduction at $W = 1900$\,MeV, line shapes and differential cross sections for $K^+\Lambda$(1405)$\rightarrow K^+\Sigma^0\pi^0$, and a peak structure in $K^0_S\Sigma^0$ photoproduction. The peak in the $K^0_S\Sigma^0$ channel appears consistent with meson-baryon generated states, where equivalent models have been used to describe the $P_C$ pentaquark candidates in the heavy charmed quark sector., Comment: Proceedings of The 12th International Workshop on the Physics of Excited Nucleons (NSTAR 2019)

The unexpected nodal structure of the beam asymmetry recently reported by the GRAAL collaboration in η′ photoproduction very close to threshold could be explained by a previously unobserved narrow resonance. The BGO-OD experiment is ideally suited to verify this measurement via the detection of forward going charged particles which in the threshold region of interest allows the identification of the reaction γp → η′ p solely based on the proton going in the forward direction. This yields unprecedented statistics if, in the missing mass analysis of the η′ meson, the background can be sufficiently well controlled. Preliminary results using a linearly polarised photon beam are shown. The reaction γp → η′ p was identified in the BGO forward spectrometer, with simulated data used to seperate signal and background.

Мета. Дослідити стан регенерації тканин у зоні трофічних виразок венозного ґенезу. Матеріали і методи. Протягом 2017 р. на базі хірургічного відділення Сумського обласного клінічного госпіталю ветеранів війни проведено лікування 57 хворих з трофічними виразками нижніх кінцівок шляхом застосування аутоплазми, збагаченої тромбоцитами (АПЗТ). Результати. На 20-ту добу від початку лікування у хворих основної групи площа виразкового дефекту зменшувалась на 45,8% у порівнянні з вихідними даними, у хворих контрольної групи - лише на 31,4%, що в 1,4 разу менше (p < 0,05). Висновки. Покращення регенерації тканин у зоні виразки за рахунок епідермізації скорочує строки її епітелізації у разі застосування АПЗТ у 2,3 разу.

Excavation below the ancient ground surface of the main courtyard (1) of the “Hellenistic” House in Nea Paphos proved its construction to be later than the beginning of the 2nd century AD. A large rectangular basin and a smaller circular one were found under the western part of the courtyard and east of it. The larger basin had two phases, the first phase being more than a meter deeper than the second one. Strata under the floors of corridor A and room B were shown to belong to the Late Classical and incipient Hellenistic periods. Exploration also continued of a cistern in the southeastern part of the courtyard and of a well in the northeastern corner of the corridor. The building sequence of the porticoes in the main courtyard was investigated in a probe dug in the southwestern corner of the court, whereas the relation between the large reception hall with mosaic floor (10) and the so-called Roman House was tested in a trench dug in corridor 29. Further fragments of “Nabatean” capitals and other decorated blocks were found in pits that had been cut in the courtyard surface in antiquity. Finally, minor excavation at the southwestern corner of the House of Aion revealed a sequence of floors against the southern elevation of a building uncovered under the late Roman street B.

Excavations in the main courtyard of the “Hellenistic” House in Nea Paphos in 2016, Polish excavations, revealed a small circular pool with immured tops of Dressel 6A amphorae in the wall surrounding it and a circular imprint in the middle of the floor. The paper undertakes a discussion of possible form and function, putting forward a tentative interpretation based on a study of parallels that we are dealing with an ornamental pool, a popular furnishing of wealthy Roman house gardens, functioning perhaps as a fishpond (piscina) or a tank with water constantly running in and out, with a labrum or columnar pedestal standing in the middle.

The γ p → K + Σ 0 differential cross section at extremely forward angles was measured at the BGOOD experiment. A three-quarter drop in strength over a narrow range in energy and a strong dependence on the polar angle of the K + in the centre-of-mass of the reaction is observed at a centre-of-mass energy of 1900 MeV. Residing close to multiple open and hidden strangeness thresholds, the structure appears consistent with meson-baryon threshold effects which may contribute to the reaction mechanism.

Maintaining of the proper predetermined paper pulp consistency on the different stages of the paper or cardboard manufacturing process significantly affects on quality and self cost of manufactured articles. The improvement of precision and repeatability of the paper pulp viscosity and consistency measurements is relevant to paper industry. Objective of the work is to improve the industrial-type paper pulp rotational consistometer. A new method for measurement of paper pulp concentration by means of a rotational viscometer was suggested which enables determining the flow consistency index K and flow behavior index n in the Ostwald-de Waele power law. The influence of the following torques on the measurement results is eliminated thanks to the new method: the friction torque in the seal of the sensitive element, the friction torque in the bearings of the shaft and the torque created under the influence of the flow with distorted flow speed profile. This is achieved by measuring the torque which acts on the sensitive element approaching the selected frequencies of sensitive element rotation both from the lower and higher frequencies. The mean torque value is calculated based on the obtained values. The measurements are conducted for two sensitive element rotation frequencies adjusted in advance. The frequency of sensitive element rotation is changed by means of a frequency converter. It is shown that by using two different rotation frequencies of the sensitive element of a rotational viscometer it is possible to define the flow consistency index and the flow behavior index. Paper pulp viscosity and consistency is defined on the basis of these two indexes. It is also suggested to average the results of viscous friction torque measurement approaching the rotation frequency of the viscometer sensitive element to the working frequency chosen for measurement from the lower and higher frequency ranges. By averaging the results of such measurement the friction torques in sealing and bearings supporting the sensitive element shaft are compensated. By changing the rotation direction of the sensitive element and by further averaging the obtained results it is possible to eliminate the influence of the asymmetrical distribution of paper pulp flow speed in the pipeline. This improves accuracy of the paper pulp consistency measurement.

The BGO-OD experiment at the ELSA accelerator facility uses an energy tagged bremstrahlung photon beam to investigate the excitation structure of the nucleon. The setup consists of a highly segmented BGO calorimeter surrounding the target, with a particle tracking magnetic spectrometer at forward angles. BGO-OD is ideal for investigating low momentum transfer processes due to the acceptance and high momentum resolution at forward angles. In particular, this enables the investigation of strangeness photoproduction where t-channel exchange mechanisms play an important role. This also allows access to a kinematic region where extended, molecular structure may manifest in reaction mechanisms. The extensive strangeness photoproduction programme includes the photoproduction of neutral and charged kaons using both hydrogen and deuterium targets.

Purpose . As part of the scientific paper it is necessary to study the waveform impact of the braking cylinders filling on longitudinal train dynamics at different modes of braking. At this one should estimate the level of maximum longitudinal forces and braking distance size in freight cars of various lengths. Methodology . In this paper we attempt to approximate the actual diagram of braking cylinders filling with rational functions of varying degrees. In selection of coefficients in the required functions the highest values of the longitudinal forces and braking distances were used as controlled parameters. They were compared with similar values obtained as a result of experimental rides. The level of longitudinal forces and braking distances amount were evaluated by means of mathematical modeling of train longitudinal vibrations, caused by different braking modes. Findings . At mathematical modeling was assumed that the train consists of 60 uniform four-axle gondola cars, weight of 80 tons, equipped with air dispenser No. 483 included in the median operation, composite braking blocks, and one locomotive VL-8. Train before braking has been pre-stretched. Various types of pneumatic braking (emergency, full service and adjusting braking) of the freight train on the horizontal section of the track were simulated. As the calculation results were obtained values of the longitudinal forces, braking distances amounts and reduction time in speed at various braking modes. Originality . Waveform impact of the braking cylinders filling on the longitudinal forces level and braking distances amount in freight trains were investigated. Also the longitudinal loading of freight trains at various pneumatic braking was investigated. Practical value . Obtained results can be used to assess the level of largest longitudinal forces and braking distances in the freight trains of different lengths by mathematical modeling of different braking modes.

Archeological work in the 2012 and 2013 seasons in Jiyeh (Porphyreon), which lies on the Phoenician coast north of ancient Sidon, was focused on reconstructing the history of settlement on the site. At least three phases were identified and dated to the Iron Age II, the Persian– Hellenistic–Roman period and late antiquity. The early dating of the functioning of the Christian basilica to the 4th–5th century AD was also confirmed in trial pits. The complex and unusual sewage installation discharging rainwater from the roofs and streets of the 5th-century settlement contributed important data for studies of late antique domestic architecture in the region.

Introduction: Information on chemical and phase composition of pancreoliths is limited and discrepant. There are reports, that pancreoliths are composed by calcium, phosphate, calcium carbonate or combination of calcium with fatty acids The aim of the work is studying of structural characteristics of pancreatoliths in 5 clinical cases.Materials and methods: Morphological and crystal-chemical study of five cases of pathological biomineralization in the pancreas were conducted in the work.Results: Two stones were located in the pancreatic duct, in other cases - in the ductal system of pancreas. Concretion sizes ranged from 0.5 to 1.5 cm in diameter. Pancreatic lithiasis' form depended on the location: in the duct of Wirsung single concretions were found (they were relatively large, oval stones with smooth, regular edges); multiple, small concretions with irregular edges, coral-like stones dominated in the ductal system of pancreas. Histological study of pancreas showed the signs of chronic pancreatitis, tissue fibrosis, atrophy and edema of glandular component, system distension of ducts, nidal mix-cell inflammatory infiltrates, vessels' plethora. Structural phase and chemical analysis of pathological biominerals responded calcite in all studied cases.Conclusion: The presence of pancreatic lithiasis was found to be accompanied by significant morphological changes of the pancreas. The pancreatolith crystal phase was established to be calcium carbonate in the form of calcite.

The BGO-OD experiment at the ELSA accelerator facility uses an energy tagged bremstrahlung photon beam to investigate the excitation spectrum of the nucleon. The setup consists of a highly segmented BGO calorimeter surrounding the target, with a particle tracking magnetic spectrometer at forward angles. BGO-OD is ideal for investigating the photoproduction of hadrons of non-zero strangeness. The high momentum resolution at forward angles covers a kinematic region where t-channel exchange mechanisms play a dominant role. Access to this low momentum transfer region also allows the investigation of degrees of freedom not derived from constituent quark models, for example, the role of (vector) meson - baryon interactions and dynamically generated states in photoproduction reactions. Data taking for the first part of an extensive physics programme is complete and preliminary results and ongoing analysis are presented. (Less)

Розглянуто передумови до перегляду стратегії електропостачання власних потреб АЕС в Україні та нові підходи до організації електропостачання споживачів систем безпеки від внутрішніх резервних джерел електроживлення і мобільних дизель-генераторних електростанцій.

Згідно результатів Європейського дослідження серцевих вад (Euro-Heart Survey on Vascular Heart Disease), серед уражень серцевих клапанів найбільш поширеною патологією є неревматичний аортальний стеноз, який також називають кальцифікованим аортальним стенозом (КАС), так як у його патогенезі головна роль належить процесу біомінералізації стулок і кільця клапану. Демографічно-обумовлене зростання кількості людей старших вікових груп призводить до збільшення дегенеративно-метаболічних захворювань серцевих аортальних клапанів (АК), особливо спричинене атеросклеротичними процесами. Метою роботи є імуногістохімічне дослідження мінералізованих тканини аортальних серцевих клапанів, уражених атерокальцинозом. Матеріали і методи. Всього було досліджено 30 зразків мінералізованих аортальних клапанів (І група) та 10 зразків аортальних клапанів без ознак біомінералізації (ІІ група), які виступали у якості контролю. У тканині АК обох груп було проведене імуногістохімічне дослідження експресії колагену І (Collagen I), CD68, мієлопероксидази (MPO), кальгрануліну А (S100A8), кальгрануліну В (S100A9), каспази 3 (Casp 3) та остеопонтину (OPN). Оцінювання статистичної достовірності різниці результатів між групами зразків проводили за допомогою непараметричного критерію Манна-Уітні. Результати вважали статистично достовірними при ступеню вірогідності більше 95% (р

The first measurement of the helicity dependence of the total inclusive 3He photo-absorption cross section and of the partial cross sections for several reaction channels was carried out at MAMI (Mainz) in the photon energy range between 150 and 500 MeV. The experiment used the large acceptance Crystal Ball spectrometer, complemented by charged particle and vertex detectors, a circularly polarised tagged photon beam and a longitudinally polarised high-pressure 3He gas target. The results obtained give information on the GDH integral on 3He and on the neutron and allow an investigation of the modifications of nucleon properties inside 3He.

Trauma is one of the leading causes of monocular blindness worldwide. Recognizing, evaluating, and managing vision-threatening injuries, such as globe rupture, retrobulbar hemorrhage, intraocular foreign bodies, and hyphemas, are paramount for emergency physicians to reduce the risk of vision loss and other complications. Other emergent ocular complaints, such as acute-angle closure glaucoma, and retinal detachment also require temporizing emergency management that can reduce complications while awaiting definitive specialty care. Understanding these conditions and evidence-based management will enable the emergency physician to provide the most up-to-date standard of care.

Objective The axillary vein is an easily accessible vessel that can be used for ultrasound-guided central vascular access and offers an alternative to the internal jugular and subclavian veins. The objective of this study was to identify which transducer orientation, longitudinal or transverse, is better for imaging the axillary vein with ultrasound. Methods Emergency medicine physicians at an inner-city academic medical center were asked to cannulate the axillary vein in a torso phantom model. They were randomized to start with either the longitudinal or transverse approach and completed both sequentially. Participants answered questionnaires before and after the cannulation attempts. Measurements were taken regarding time to completion, success, skin punctures, needle redirections, and complications. Results Fifty-seven operators with a median experience of 85 ultrasound procedures (interquartile range, 26-120) participated. The frequency of first-attempt success was 39 (0.69) of 57 for the longitudinal method and 21 (0.37) of 57 for the transverse method (difference, 0.32; 95% confidence interval [CI], 0.12-0.51 [ P = .001]); this difference was similar regardless of operator experience. The longitudinal method was associated with fewer redirections (difference, 1.8; 95% CI, 0.8-2.7 [ P = .0002]) and skin punctures (difference, 0.3; 95% CI, −2 to +0.7 [ P = .07]). Arterial puncture occurred in 2 of 57 longitudinal and 7 of 57 transverse attempts; no pleural punctures occurred. For successful attempts, the time spent was 24 seconds less for the longitudinal method (95% CI, 3-45 [ P = .02]). Conclusions The longitudinal method of visualizing the axillary vein during ultrasound-guided venous access is associated with greater first-attempt success, fewer needle redirections, and a trend of fewer arterial punctures compared with the transverse orientation.

The new BGO-OD experiment at the electron accelerator ELSA, of the University of Bonn, is designed to study the reaction dynamics of nucleon excitations in meson photoproduction. It consists of a central BGO calorimeter with a magnetic spectrometer in forward direction. The physics programme includes the measurement of polarisation observables using linearly and circularly polarised photon beams. Linear polarisation is obtained by coherent bremsstrahlung off a diamond crystal, and circular polarisation is obtained via bremsstrahlung from longitudinally polarised electrons. The degree of linear polarisation is determined from the bremsstrahlung spectrum itself. To determine the polarisation of the circularly polarised photon beam, the polarisation of the electron beam is measured by a Moller polarimeter. As a preliminary consistency check, the (linear) polarisation observable, Σ, was compared to world data for π^0 and η photoproduction. To determine the degree of circular polarisation, a Moller polarimeter was setup and first measurements of the electron beam polarisation performed.

BGO-OD is a new meson photoproduction experiment at the ELSA facility of Bonn University. It aims at the investigation of non strange and strange baryon excitations, and is especially designed to be able to detect weekly bound meson-baryon type structures. The setup for the BGO-OD experiment is presented, the characteristics of the photon beam and the detector performances are shown and the initial experimental program is discussed.

BGO-OD is a newly commissioned experiment to investigate the internal structure of the nucleon, using an energy tagged bremsstrahlung photon beam at the ELSA electron facility. The setup consists of a highly segmented BGO calorimeter surrounding the target, with a particle tracking magnetic spectrometer at forward angles. BGO-OD is ideal for investigating meson photoproduction. The extensive physics programme for open strangeness photoproduction is introduced, and preliminary analysis presented., 6 pages, 4 figures. Proceedings for the 10th International Workshop on the Physics of Excited Nucleons (NSTAR2015)

It is developed a new approach to analyze the induced fission of heavy nuclei, which takes into account the nuclear dissipation phenomenon and the shell structure of nuclei in determination of fission barriers. The approach is based on the combined dynamical and statistical simulations. In the framework of this approach the method of calculation the fission fragment angular distributions in a wide energy range is discussed. The ability of the method is demonstrated in the simultaneous description of the experimental data of the fission probabilities on the Am and Pu nuclei, yields of the spontaneous fission of isomers for the α + 238 U reaction at E α = (20 - 32) MeV and the d + 242,240 Pu reactions at E d = (20 - 30) MeV , the fission times for the α + 238 U reaction and angular distribution of fission fragments for the α + 238 U , 237 Np reactions at E α = (20 - 100) MeV . A further information on the value of the nuclear dissipation at low excitation energies is obtained. In addition, it is demonstrated that the influence of the shell effects on the deformation potential energy holds up to excitation energies of about (50 - 60) MeV.