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8. List of Contributors

Author

Y. Al-Douri, Periasamy Anbu, Leonard Sean Anthony, M.K. Md Arshad, Sharma Rao Balakrishnan, Alfarooq O. Basheer, Audesh Bhat, Arti Dhar, Fatin Nabilah Mohd Faudzi, C.A.N. Fernando, Subash C.B. Gopinath, Azrul Azlan Hamzah, Uda Hashim, V.C. Hong, M Isa A, S. Jayanthi, Jaspreet Kalra, Roohi Kesharwani, Shing Fhan Khor, Vandana Krishna, Vikas Kumar, Thangavel Lakshmipriya, Iswary Letchumanan, Narendra Maddu, Norani Muti Mohamed, Sh. Nadzirah, Nor A. Parmin, Dilip Kumar Patel, Veeradasan Perumal, Prabakaran Poopalan, R.D.A.A. Rajapaksha, Santheraleka Ramanathan, BollaReddy S.V. Reddy, Tinesha Selvaraj, Theivasanthi Thirugnanasambandan, M.N. Afnan Uda, M.N.A. Uda, Palaniyandi Velusamy, Venkata V.K. Venuganti, Ahmad Radi Wan Yaakub, Yunfeng Fu, Yanwei Luo, Haoyu Li, Jian Li, and Wei Huang

Published
2021
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9. Diagnosing metabolic diseases by nanoparticle immobilization

Author

Nor A. Parmin, Uda Hashim, Subash C.B. Gopinath, Sh. Nadzirah, M.N.A. Uda, M.N. Afnan Uda, V.C. Hong, M Isa A, and Ahmad Radi Wan Yaakub

Subjects
Heart disease, business.industry, Glucose Metabolism Disorder, Metabolic disorder, Medicine, Metabolic Brain Disease, Blood sugar, Disease, Type 2 diabetes, business, medicine.disease, Bioinformatics, Stroke
Abstract

Metabolic disease is a group of conditions that expand the risk of heart disease, stroke, and type 2 diabetes. High blood sugar, blood pressure, excess body fat around the waist, and abnormal cholesterol or triglyceride levels are included in this kind of metabolic disease that seems dangerous to human beings. The development of metabolic disease happened when the organs, such as the liver and pancreas did not function properly and triggered metabolic disease. Metabolic diseases happen at the point when irregular compound responses in the human body can modify the typical metabolic procedures. Metabolic diseases can be defined as an inherited single gene, mostly autosomal recessive. The principal classes of metabolic diseases include metabolic brain diseases, calcium metabolism disorder, acid-base imbalance, and glucose metabolism disorders. Diagnosing metabolic diseases was tedious and depending on which type of disease was involved, and currently, by using DNA tests, we can identify the disease but it takes several hours and only a professional person in charge can analyze the result. Advances in diagnosing metabolic diseases by nanoparticle immobilization establish a promising exploration area with favorable impacts on the treatment of diseases. Nanotechnology based on nanoparticle implementation was useful for the metabolic disorder diagnosis to prevent the disease from going viral to develop. Biosensor based on nanoparticles has been applied in several detections including metabolic illnesses to improve accessible analytical methods. Point-of-care (POC) sensor devices have been developed for metabolic disease and offer outcomes, quicker, simpler and at a lower cost than conventional methods. It also can be used in remote regions for metabolic diagnosis. In this chapter, different nanoparticle immobilization has been discussed to diagnose metabolic diseases by using it in clinical approach.

Published
2021
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