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1. Microwave Assisted Synthesis of 3-Chloro-N-(2-(5-chloro-1-tosyl-1Hbenzo [d] Imidazol-2-yl) ethyl)-N-Substituted Quinoxalin-2-Amine Derivatives Using DCQX

Author

M.Thirumala Chary, E. Laxminarayana, M. Ramesh, and K. Shashikala

Subjects
chemistry.chemical_compound, Tosyl, chemistry, Microwave assisted, Medicinal chemistry, Amine derivatives
Abstract

The microwave assisted synthesis of 3-Chloro-N-(2-(5-chloro-1-tosyl-1H-benzo [d] imidazol-2-yl) ethyl)-N-substituted quinoxalin-2-amine derivatives is described. 2,3-dichloro quinoxaline (DCQX), as a starting compound and propargyl bromide, as an efficient alkylating agent are used in the synthesis of N-substituted quinoxalin-2-amine derivatives. We realized that microwave assisted synthesis is efficiently replacing conventional method of synthesis.

Published
2020

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