332 results on '"MAINTAIN"'
Search Results
2. 1‐甲基环丙烯结合水杨酸处理维持百香果 果实贮藏品质.
- Author
-
杨秀群, 谢国芳, 袁孟孟, and 娄杰
- Abstract
Copyright of Food Research & Development is the property of Food Research & Development Editorial Department and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
- Published
- 2024
- Full Text
- View/download PDF
3. Dietary free L-glutamate contributes to maintaining a low sodium intake among Vietnamese
- Author
-
Vu Thi Thu Hien, Le Danh Tuyen, Andrea Wakita, Saiko Shikanai, Le Thi Hang, Nguyen Thi Diep Anh, Nguyen Thi Anh Nguyet, Tamami Iwamoto, Hideki Matsumoto, Hisayuki Uneyama, Nguyen Vu Son, Nguyen Nhat Linh, and Shigeru Yamamoto
- Subjects
free L-glutamate ,umami ,sodium intake ,cross-over ,dietary ,maintain ,Nutrition. Foods and food supply ,TX341-641 - Abstract
BackgroundThe World Health Organization (WHO) and the Food and Agriculture Organization (FAO) recommend the consumption of less than 2,000 mg of sodium/day to reduce blood pressure and the risk of conditions such as cardiovascular disease and coronary heart disease. The sodium intake among Vietnamese was reported to be 7,200 mg/d or more. Free L-glutamate enhances flavor when it is added to food and improves the taste of sodium-reduced foods.ObjectiveThis study aims to investigate whether the intake of free L-glutamate-rich seasonings contributes to maintaining a low sodium intake in a cross-over study.MethodsFrom a total of 145 subjects, 42 participants were screened for participation in the cross-over design study. Subjects were randomly allocated to the Low free L-glutamate group (Low free L-Gl) and the Normal free L-glutamate group (Normal free L-Gl). Both received a direct educational guideline to reduce sodium intake. The Low free L-Gl group started with a restriction in the variety of free L-glutamate-rich seasonings, and the Normal free L-Gl group had no restriction in the variety of seasonings. Blood pressure was measured at week 0 (baseline), week 2, week 4, and week 6, while body weight, height, urine sodium and potassium excretion, chromogranin-A (CgA pmol/mg protein) from saliva, and free L-glutamate from food were measured at week 0, week 3, and week 6.ResultsIn Low free L-Gl, the amount of free L-glutamate in food decreased significantly from baseline to week 6 (p 0.05). However, the reduction of sodium excretion at week 6 was 22% in Low free L-Gl (5,875 mg/d vs. 4,603 mg/d, p
- Published
- 2024
- Full Text
- View/download PDF
4. 有林单位森林防火蓄水池建设调查研究——以深圳市为例.
- Author
-
钟映霞, 王振师, 周世均, 王明怀, 魏书精, 周宇飞, 罗斯生, 吴泽鹏, and 许秀玉
- Abstract
Copyright of Journal of Wildland Fire Science is the property of Journal of Wildland Fire Science Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
- Published
- 2023
- Full Text
- View/download PDF
5. Challenges against the identity of Kangasia (Regarding Bhavnagar District)
- Author
-
Rayjada, Jaydevsinh B.
- Published
- 2023
- Full Text
- View/download PDF
6. Analysis of Inspection and Maintenance Methods for Thermal Power Plant
- Author
-
Chen, Jingru, Xue, Chenxi, Wang, Yuteng, Qian, Chao, Zhu, Qing, Angrisani, Leopoldo, Series Editor, Arteaga, Marco, Series Editor, Chakraborty, Samarjit, Series Editor, Chen, Jiming, Series Editor, Chen, Shanben, Series Editor, Chen, Tan Kay, Series Editor, Dillmann, Rüdiger, Series Editor, Duan, Haibin, Series Editor, Ferrari, Gianluigi, Series Editor, Ferre, Manuel, Series Editor, Jabbari, Faryar, Series Editor, Jia, Limin, Series Editor, Kacprzyk, Janusz, Series Editor, Khamis, Alaa, Series Editor, Kroeger, Torsten, Series Editor, Li, Yong, Series Editor, Liang, Qilian, Series Editor, Martín, Ferran, Series Editor, Ming, Tan Cher, Series Editor, Minker, Wolfgang, Series Editor, Misra, Pradeep, Series Editor, Mukhopadhyay, Subhas, Series Editor, Ning, Cun-Zheng, Series Editor, Nishida, Toyoaki, Series Editor, Oneto, Luca, Series Editor, Panigrahi, Bijaya Ketan, Series Editor, Pascucci, Federica, Series Editor, Qin, Yong, Series Editor, Seng, Gan Woon, Series Editor, Speidel, Joachim, Series Editor, Veiga, Germano, Series Editor, Wu, Haitao, Series Editor, Zamboni, Walter, Series Editor, Zhang, Junjie James, Series Editor, Dhar, Sourav, editor, Do, Dinh-Thuan, editor, Sur, Samarendra Nath, editor, and Liu, Chuan-Ming, editor
- Published
- 2023
- Full Text
- View/download PDF
7. SOLAR HEATING SYSTEM FOR THE MAINTAINING OF BATTERIES CHARGE.
- Author
-
BEJENAR, Ciprian, ABU-BANDORA, Mahmoud, IFRIM, Visarion-Cătălin, and ALISAVETEI, Irina
- Subjects
- *
ELECTRICAL energy , *SOLAR heating , *ENERGY conversion , *BATTERY storage plants - Abstract
This paper presents an invention that relates to a solar heating system, integrable in the constructive structure of a vehicle, intended to maintain the temperature and/or charge level of the batteries it disposes of. In this purpose, the phenomenon is controlled through the specific constructive form that facilitates the conversion of solar energy, both in thermal energy as well as in electrical energy and because the system involves thermo-mechanical actuators. These actuators offer autonomous operation, suitable in the automatic regulation of this process. [ABSTRACT FROM AUTHOR]
- Published
- 2023
8. Circular Economy: A Decision-Support Model for Recirculation Strategies.
- Author
-
Petry, Michelle and Köhler, Christian
- Subjects
DECISION making ,WASTE management ,PRODUCT life cycle ,SUSTAINABILITY ,GLOBALIZATION - Abstract
Increasing individualization, interconnectivity, globalization and technical innovations are shortening product life cycles. In combination with the established linear thinking in the product life cycle, many products are disposed in a usable condition after a short use phase and the potential of the Circular Economy is insufficiently used today. At the same time, there are social and political expectations for companies to implement sustainability in order to conserve resources, avoid waste and limit CO2 emissions. Today, the decision whether and which recirculation strategy to apply is made by elaborate individual business cases. Therefore, an application-oriented decision model was developed and validated in the context of production equipment with a practical partner, which assesses the usefulness and benefits of an after-use phase of products and resources and thus helps companies to identify suitable recirculation strategies more efficiently and to increase the effectiveness in offering sustainable products and services. [ABSTRACT FROM AUTHOR]
- Published
- 2022
9. Adaptive Electronic Health Records Management and Secure Distribution Using Blockchain
- Author
-
Jagadamba, G., Krishna, E. L. Sai, Amogh, J. P., Abhishek, B. B., Manoj, H. N., Kacprzyk, Janusz, Series Editor, Gomide, Fernando, Advisory Editor, Kaynak, Okyay, Advisory Editor, Liu, Derong, Advisory Editor, Pedrycz, Witold, Advisory Editor, Polycarpou, Marios M., Advisory Editor, Rudas, Imre J., Advisory Editor, Wang, Jun, Advisory Editor, Giri, Debasis, editor, Mandal, Jyotsna Kumar, editor, Sakurai, Kouichi, editor, and De, Debashis, editor
- Published
- 2022
- Full Text
- View/download PDF
10. Epicardial connection(s) inside the pulmonary vein antrum isolation lines contribute to subsequent atrial fibrillation: a case report.
- Author
-
Fujiwara, Masaki, Takemoto, Masao, Koga, Tokushi, and Tsuchihashi, Takuya
- Abstract
Aims Recent reports have demonstrated that ∼10% of patients with atrial fibrillation (AF) have epicardial connections (ECs) inside the pulmonary vein (PV) antrum isolation (AI) (PVAI) lines, which could be a possible mechanism of failure to achieve a complete PVAI, thus contributing to AF recurrence. Case summary We present an 80-year-old female case with consistently continuing AF associated with ECs. Epicardial connections involving the PVs were detected in the left and right superior PVs after the completion of the PVAI. The AF steadily terminated after the ablation of those ECs. She has remained well without any AF or symptoms for 2 years post-ablation. Discussion Those ECs might have played a possible important role in initiating and maintaining the AF. The mechanism(s) of the ECs may be a cornerstone of the failure to achieve a complete PVAI contributing to AF recurrence. Ablation of the EC(s) in addition to the PVAI may be better able to achieve the completion of the PVAI. Thus, physicians should be aware of the possibility of the presence of EC(s) when performing ablation of AF, even though complete PVAI lines have been achieved. [ABSTRACT FROM AUTHOR]
- Published
- 2023
- Full Text
- View/download PDF
11. The Potential of an Inexpensive Plant-Based Medium for Halal and Vegetarian Starter Culture Preparation.
- Author
-
Ayu, Bella Tiara, Chamnipa, Nuttaporn, and Apiraksakorn, Jirawan
- Subjects
VEGETARIAN foods ,SWEET potatoes ,LACTIC acid bacteria ,HALAL food ,VEGETARIANS - Abstract
The restrictions for halal and vegetarian fermented products apply not only to the food ingredients, but also to the inoculum media. The utilization of a medium for lactic acid bacteria (LAB) leads to some issues from animal-derived proteins sources that may be doubtful for halal and/or vegetarian use. This study aimed to develop a plant-based medium for culturing and maintaining LAB. The result demonstrated that 10 g/L soybean powder in sweet potato extract was suitable for cultivating Lactiplantibacillus plantarum TISTR 2075 with no significant difference (p < 0.05) from MRS (de Man, Rogosa and Sharpe) in the cell number (9.12 log CFU/mL) and specific growth rate (0.04). The feasibility of a plant-based medium to grow and maintain the LAB strains from different origins was evaluated. Compared to MRS, Lpb. plantarum TISTR 2075, Lpb. plantarum MW3, and Lacticaseibacillus casei TISTR 1463 could grow almost as well in a plant-based medium. This medium was also suitable for maintaining the viability of LAB during storage, especially when subjected to slant agar stock culture. It is practical and costs at least 10 times less than MRS. Thus, this study created a low-cost plant-based medium that could be used in laboratories, especially for applications in halal and vegetarian food products. [ABSTRACT FROM AUTHOR]
- Published
- 2023
- Full Text
- View/download PDF
12. Maintaining Aesthetic Aspects in Translation Literary Texts.
- Author
-
Saif Ashujaify, Ebrahim Saif
- Subjects
- *
LITERATURE translations , *GRADUATE education , *AESTHETICS , *JUDGMENT sampling , *ARABIC literature - Abstract
Abstract : This study aims at identifying the abilities of MA translation students at Yemeni Academy for Post- Graduated Studies to translate the different literary texts and maintain the aesthetic aspects. The main aim of the study was answering the question to what extent can MA translation students at Yemen Academy for Graduate Studies maintain the aesthetic aspects of the source text when translating from English into Arabic? The researcher selects a purposive sample of MA students (males and females). The researcher designs a translation test that consists of group of English texts quoted from different resources and goes on through the process of validation done by specialists in the field and administers it to the students. The results show the difficulties when translating literary texts and maintaining aesthetics aspects from the point of view of the MA students for different reasons. At the end, the researcher provided some important recommendations: students should take account to literary texts as same as legal and commercial texts. Students should avoid literal strategies and know that their mother language has a lot of aesthetics. Students should practice translation and read more in their own language and that can help them to transfer the meaning in good way. [ABSTRACT FROM AUTHOR]
- Published
- 2022
13. Development and evaluation of the MAINTAIN instrument, selecting patients suitable for secondary or tertiary preventive manual care: the Nordic maintenance care program
- Author
-
Andreas Eklund, Per J. Palmgren, Ulf Jakobsson, and Iben Axén
- Subjects
MAINTAIN ,Clinical instrument ,Low back pain ,Stratified care ,Chiropractic ,Prevention ,RZ201-275 ,Diseases of the musculoskeletal system ,RC925-935 - Abstract
Abstract Background Chiropractic maintenance care (MC) has been found to be effective for patients classified as dysfunctional by the West Haven-Yale Multidimensional Pain Inventory (MPI). Although displaying good psychometric properties, the instrument was not designed to be used in clinical practice to screen patients for stratified care pathways. The aim was to develop a brief clinical instrument with the intent of identifying dysfunctional patients with acceptable diagnostic accuracy. Methods Data from 249 patients with a complete MPI dataset from a randomized clinical trial that investigated the effect and cost-effectiveness of MC with a 12-month follow-up was used in this cross-sectional analysis. A brief screening instrument was developed to identify dysfunctional patients, with a summary measure. Different cut-offs were considered with regards to diagnostic accuracy using the original instrument’s classification of dysfunctional patients as a reference. Very good diagnostic accuracy was defined as an area under the curve (AUC) metric between 0.8 and 0.9. The instrument was then externally validated in 3 other existing datasets to assess model transportability across populations and medical settings. Results Using an explorative approach, the MAINTAIN instrument with 10 questions (0–6 Likert responses) capturing 5 dimensions (pain severity, interference, life control, affective distress, and support) was developed, generating an algorithm-based score ranging from − 12 to 48. Reporting a MAINTAIN score of 18 or higher, 146 out of the 249 patients were classified as dysfunctional with 95.8% sensitivity and 64.3% specificity. At a score of 22 or higher, 109/249 were classified as dysfunctional with 81.1% sensitivity and 79.2% specificity. AUC was estimated to 0.87 (95% CI 0.83, 0.92) and Youden’s index was highest (0.70) at a score of 20. The diagnostic accuracy was similar and high across populations with minor differences in optimal thresholds for identifying dysfunctional individuals. Conclusion The MAINTAIN instrument has very good diagnostic accuracy with regards to identifying dysfunctional patients and may be used as a decision aid in clinical practice. By using 2 thresholds, patients can be categorized into “low probability (− 12 to 17)”, “moderate probability (18 to 21)”, and “high probability (22 to 48)” of having a good outcome from maintenance care for low back pain. Trial registration Clinical trials.gov; NCT01539863; registered February 28, 2012; https://clinicaltrials.gov/ct2/show/NCT01539863 .
- Published
- 2022
- Full Text
- View/download PDF
14. Factors Affecting the Perception of the Surrounding Community in Maintaining the Sustainability of the Setu Babakan Betawi Cultural Village in South Jakarta
- Author
-
Suberlian, Dwinanto, Chotib, Emamian, Seyed Sattar, editor, Adekunle, Timothy O., editor, Nangkula, Utaberta, editor, and Awang, Mokhtar, editor
- Published
- 2021
- Full Text
- View/download PDF
15. Ex-situ conservation of PGR in the National seed genebank of Bulgaria - past, present and future.
- Author
-
Desheva, Gergana, Valchinova, Evgenia, and Deshev, Manol
- Subjects
PLANT germplasm ,CULTIVARS ,GERMPLASM conservation ,PLANT breeding ,REGIONAL cooperation ,SEEDS - Abstract
The ex situ conservation of plant genetic resources in seed genebank plays an important role for food security in the future. The National Genebank of Bulgaria is located on the territory of the Institute of Plant Genetic Resources “K. Malkov” - Sadovo. It was built in 1984 and carry out a scientific programme for long-term preservation of germplasm with seeds under controlled conditions in accordance with the standards, developed by FAO. The total number of registered accessions in the Genebank is above 60 000, where 44572 are preserved in the base collection. These accessions are representatives of 32 families, 150 genera, 600 plant species. Total 10 193 of the accessions originated from Bulgaria. The accessions received abroad originated from more than 80 countries. Germplasm material consists of: local population, old cultivars, advanced varieties, breeding lines. The genetic stocks are available for research and for plant breeding, further utilisation by international and regional co-operation, free exchange of plant genetic resources according to CBD and conditions contained in the standard material transfer agreement. [ABSTRACT FROM AUTHOR]
- Published
- 2022
16. Prevalence and mortality of transient acute kidney injury within 48 h, as new subtype, following coronary angiography: a cohort study.
- Author
-
Li, Qiang, Lin, Mengfei, Huang, Haozhang, Liu, Liwei, Chen, Weihua, Huang, Dehua, Tang, Ronghui, Zhao, Miao, Wei, Wen, Wang, Bo, Huang, Zhidong, Tan, Ning, Chen, Jiyan, Chen, Shiqun, Liu, Jin, and Liu, Yong
- Subjects
- *
ACUTE kidney failure , *CORONARY angiography , *COHORT analysis , *MORTALITY - Abstract
Background: The association of transient acute kidney injury (AKI) with mortality was controversial. Our study aims to investigate the prevalence and impact of transient AKI on mortality in patients following coronary angiography (CAG). Methods: Our study retrospectively enrolled 3970 patients with pre-operative serum creatinine (Scr) and twice measurements within 48 h after procedure. Transient AKI defined as the diagnosis of AKI (Scr > 0.3 mg/dL or > 50% from the baseline level) on day 1 when Scr failed to meet the criteria for AKI on the day 2. Maintained AKI was defined as AKI not meeting the definition for transient AKI. The primary outcome was 1-year all-cause mortality. Multivariable logistic regression was used to assess the association between transient AKI and 1-year mortality. Results: Among 3,970 participants, 861 (21.7%) occurred AKI, of whom 128 (14.9%) was transient AKI and 733 (85.1%) was maintained AKI. 312 (7.9%) patients died within 1-year after admission. After multivariable analysis, transient AKI was not associated with higher 1-year mortality [adjusted odds ratio (aOR), 1.37; CI 0.68–2.51] compared without AKI. Among AKI patients, transient AKI was associated with a 52% lower 1-year mortality compared with maintained AKI. Additionally, maintained AKI was significantly associated with higher 1-year mortality (aOR, 2.67; CI 2.05–3.47). Conclusions: Our data suggested that transient AKI within 48 h was a common subtype of AKI following CAG, without increasing mortality. More attention needs to be paid to the patients suffering from maintained AKI following CAG. [ABSTRACT FROM AUTHOR]
- Published
- 2022
- Full Text
- View/download PDF
17. Development and evaluation of the MAINTAIN instrument, selecting patients suitable for secondary or tertiary preventive manual care: the Nordic maintenance care program.
- Author
-
Eklund, Andreas, Palmgren, Per J., Jakobsson, Ulf, and Axén, Iben
- Subjects
DISEASE relapse prevention ,EXPERIMENTAL design ,RESEARCH ,RESEARCH evaluation ,RESEARCH methodology ,PATIENT selection ,CROSS-sectional method ,MEDICAL screening ,MEDICAL care ,PATIENTS ,PSYCHOMETRICS ,PREVENTIVE health services ,SCALE analysis (Psychology) - Abstract
Background: Chiropractic maintenance care (MC) has been found to be effective for patients classified as dysfunctional by the West Haven-Yale Multidimensional Pain Inventory (MPI). Although displaying good psychometric properties, the instrument was not designed to be used in clinical practice to screen patients for stratified care pathways. The aim was to develop a brief clinical instrument with the intent of identifying dysfunctional patients with acceptable diagnostic accuracy. Methods: Data from 249 patients with a complete MPI dataset from a randomized clinical trial that investigated the effect and cost-effectiveness of MC with a 12-month follow-up was used in this cross-sectional analysis. A brief screening instrument was developed to identify dysfunctional patients, with a summary measure. Different cut-offs were considered with regards to diagnostic accuracy using the original instrument's classification of dysfunctional patients as a reference. Very good diagnostic accuracy was defined as an area under the curve (AUC) metric between 0.8 and 0.9. The instrument was then externally validated in 3 other existing datasets to assess model transportability across populations and medical settings. Results: Using an explorative approach, the MAINTAIN instrument with 10 questions (0–6 Likert responses) capturing 5 dimensions (pain severity, interference, life control, affective distress, and support) was developed, generating an algorithm-based score ranging from − 12 to 48. Reporting a MAINTAIN score of 18 or higher, 146 out of the 249 patients were classified as dysfunctional with 95.8% sensitivity and 64.3% specificity. At a score of 22 or higher, 109/249 were classified as dysfunctional with 81.1% sensitivity and 79.2% specificity. AUC was estimated to 0.87 (95% CI 0.83, 0.92) and Youden's index was highest (0.70) at a score of 20. The diagnostic accuracy was similar and high across populations with minor differences in optimal thresholds for identifying dysfunctional individuals. Conclusion: The MAINTAIN instrument has very good diagnostic accuracy with regards to identifying dysfunctional patients and may be used as a decision aid in clinical practice. By using 2 thresholds, patients can be categorized into "low probability (− 12 to 17)", "moderate probability (18 to 21)", and "high probability (22 to 48)" of having a good outcome from maintenance care for low back pain. Trial registration: Clinical trials.gov; NCT01539863; registered February 28, 2012; https://clinicaltrials.gov/ct2/show/NCT01539863. [ABSTRACT FROM AUTHOR]
- Published
- 2022
- Full Text
- View/download PDF
18. Why Indonesia Maintain Capital Punishment?
- Author
-
Ahmad Irzal Fardiansyah
- Subjects
death penalty ,indonesia ,maintain ,Law in general. Comparative and uniform law. Jurisprudence ,K1-7720 - Abstract
The death penalty in Indonesia is still maintained to combat crime within the Indonesian criminal law reform. Although many states have it removed, Indonesia would have the sole discretion to keep it. Despite the opposition, the death penalty application still has a juridical and sociological basis, so it is still legal to be maintained. Indonesia itself has overshadowed the death penalty with a form of legality according to international law so that the position of Indonesia that still maintain the death penalty cannot be blamed. Moreover, sociologically, Indonesian people still accept those who commit an offence who may have profound implications that could lead to the death penalty. This issue is what became the basis for lawmakers in Indonesia to keep it. This research uses the doctrinal method toexamine various regulations regarding capital punishment and non-doctrinal to understand the community's situation related to the existence of capital punishment in Indonesia. The death penalty is a more effective deterrent and therefore prevents crime better. With the death penalty, others were about to commit a similar crime is expected not to commit the crime. The death penalty is more effectively immobilizing offenders. Perpetrators, in principle, still manage to have the desire to commit the crime again after release. The death penalty for perpetrators of crimes is not a violation of human rights, but rather to respect human rights itself, namely for victims of crime. The setting and the application of the death penalty in Indonesia until now is still needed. They are considering that there are still many crimes that undermine humanity's values or the crimes that harm the State and crackdown on corruption in society.
- Published
- 2021
- Full Text
- View/download PDF
19. Efficacy and Safety of Ixekizumab Through 5 Years in Moderate-to-Severe Psoriasis: Long-Term Results from the UNCOVER-1 and UNCOVER-2 Phase-3 Randomized Controlled Trials
- Author
-
Craig Leonardi, Kristian Reich, Peter Foley, Hideshi Torii, Sascha Gerdes, Lyn Guenther, Melinda Gooderham, Laura K. Ferris, Christopher E. M. Griffiths, Hany ElMaraghy, Heidi Crane, Himanshu Patel, Russel Burge, Gaia Gallo, David Shrom, Ann Leung, Chen-Yen Lin, and Kim Papp
- Subjects
Ixekizumab ,Long-term efficacy ,Long-term safety ,Maintain ,Psoriasis ,Quality of life ,Dermatology ,RL1-803 - Abstract
Abstract Introduction Ixekizumab, a high-affinity monoclonal antibody that selectively targets interleukin-17A, is approved for treatment of moderate-to-severe plaque psoriasis. Our objective was to evaluate the long-term efficacy and safety of ixekizumab in moderate-to-severe plaque psoriasis through 5 years. Methods Data were integrated from the UNCOVER-1 and UNCOVER-2, randomized, double-blinded, phase-3 trials. Patients who continuously received the labeled ixekizumab dose, were static Physician’s Global Assessment (sPGA) (0,1) responders at Week 12 and completed 60 weeks of treatment could enter the long-term extension (LTE) period. Patients could escalate to every-2-week dosing per investigator opinion. Efficacy and health outcomes included proportion of patients achieving Psoriasis Area and Severity Index (PASI) 75/90/100, sPGA (0,1) and (0), absolute PASI ≤ 5/ ≤ 3/ ≤ 2/ ≤ 1 and Dermatology Life Quality Index (DLQI) (0,1). Results exclude patients who escalated to every-2-week dosing. A modified non-responder imputation method was used to account for missing data. Supplemental analyses include patients who escalated to every-2-week dosing and observed and multiple imputation results. Exposure-adjusted safety outcomes are also reported. Results Of 206 patients who entered the LTE periods, 172 completed treatment. At Week 60, PASI 75/90/100 responses were 94.7%, 85.0% and 62.1%, respectively, and at year 5 were 90.3%, 71.3% and 46.3%, respectively. Similarly, meaningful responses were achieved for the other efficacy and health measures. Among patients with PASI 100 through 5 years, 92% achieved DLQI (0,1), indicating no impact of skin disease on quality of life. During the LTE period, exposure-adjusted incidence rates were 31.4 per 100 patient-years for treatment-emergent adverse events and 6.8 per 100 patient-years for serious adverse events. No deaths were reported. No new or unexpected safety findings were noted. Conclusions The results demonstrate 80 mg ixekizumab maintains long-term efficacy and a safety profile consistent with previous data in patients with moderate-to-severe plaque psoriasis through 5 years of treatment. Trial Registration ClinicalTrials.gov identifier, UNCOVER-1: NCT01474512, UNCOVER-2: NCT01597245.
- Published
- 2020
- Full Text
- View/download PDF
20. The Potential of an Inexpensive Plant-Based Medium for Halal and Vegetarian Starter Culture Preparation
- Author
-
Bella Tiara Ayu, Nuttaporn Chamnipa, and Jirawan Apiraksakorn
- Subjects
animal-free medium ,low-cost medium ,stock culture ,maintain ,viability ,Fermentation industries. Beverages. Alcohol ,TP500-660 - Abstract
The restrictions for halal and vegetarian fermented products apply not only to the food ingredients, but also to the inoculum media. The utilization of a medium for lactic acid bacteria (LAB) leads to some issues from animal-derived proteins sources that may be doubtful for halal and/or vegetarian use. This study aimed to develop a plant-based medium for culturing and maintaining LAB. The result demonstrated that 10 g/L soybean powder in sweet potato extract was suitable for cultivating Lactiplantibacillus plantarum TISTR 2075 with no significant difference (p < 0.05) from MRS (de Man, Rogosa and Sharpe) in the cell number (9.12 log CFU/mL) and specific growth rate (0.04). The feasibility of a plant-based medium to grow and maintain the LAB strains from different origins was evaluated. Compared to MRS, Lpb. plantarum TISTR 2075, Lpb. plantarum MW3, and Lacticaseibacillus casei TISTR 1463 could grow almost as well in a plant-based medium. This medium was also suitable for maintaining the viability of LAB during storage, especially when subjected to slant agar stock culture. It is practical and costs at least 10 times less than MRS. Thus, this study created a low-cost plant-based medium that could be used in laboratories, especially for applications in halal and vegetarian food products.
- Published
- 2023
- Full Text
- View/download PDF
21. Dietary free L-glutamate contributes to maintaining a low sodium intake among Vietnamese.
- Author
-
Hien VTT, Tuyen LD, Wakita A, Shikanai S, Hang LT, Anh NTD, Nguyet NTA, Iwamoto T, Matsumoto H, Uneyama H, Son NV, Linh NN, and Yamamoto S
- Abstract
Background: The World Health Organization (WHO) and the Food and Agriculture Organization (FAO) recommend the consumption of less than 2,000 mg of sodium/day to reduce blood pressure and the risk of conditions such as cardiovascular disease and coronary heart disease. The sodium intake among Vietnamese was reported to be 7,200 mg/d or more. Free L-glutamate enhances flavor when it is added to food and improves the taste of sodium-reduced foods., Objective: This study aims to investigate whether the intake of free L-glutamate-rich seasonings contributes to maintaining a low sodium intake in a cross-over study., Methods: From a total of 145 subjects, 42 participants were screened for participation in the cross-over design study. Subjects were randomly allocated to the Low free L-glutamate group (Low free L-Gl) and the Normal free L-glutamate group (Normal free L-Gl). Both received a direct educational guideline to reduce sodium intake. The Low free L-Gl group started with a restriction in the variety of free L-glutamate-rich seasonings, and the Normal free L-Gl group had no restriction in the variety of seasonings. Blood pressure was measured at week 0 (baseline), week 2, week 4, and week 6, while body weight, height, urine sodium and potassium excretion, chromogranin-A (CgA pmol/mg protein) from saliva, and free L-glutamate from food were measured at week 0, week 3, and week 6., Results: In Low free L-Gl, the amount of free L-glutamate in food decreased significantly from baseline to week 6 ( p < 0.00), while it did not change in the Normal free L-Gl ( p > 0.05). However, the reduction of sodium excretion at week 6 was 22% in Low free L-Gl (5,875 mg/d vs. 4,603 mg/d, p < 0.01) and 46% in Normal free L-Gl (6,107 mg/d vs. 3,277 mg/d, p < 0.00), both lower than the baseline. CgA (pmol/mg protein) did not show any difference between the two groups., Conclusion: The group with Normal free L-Gl intake showed a 46% reduction in sodium excretion by week 6 compared to the baseline. This suggests that the consumption of L-glutamate-rich seasonings when complemented with direct educational guidelines, can contribute to maintaining a low sodium intake., Competing Interests: AW, HM, and HU were employed by Ajinomoto Co., Inc. The remaining authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest., (Copyright © 2024 Hien, Tuyen, Wakita, Shikanai, Hang, Anh, Nguyet, Iwamoto, Matsumoto, Uneyama, Son, Linh and Yamamoto.)
- Published
- 2024
- Full Text
- View/download PDF
22. Financial Forces for Women Entrepreneurs in Rural Development.
- Author
-
Vaishnavi, S. and Hariharan, S.
- Subjects
RURAL development ,BUSINESSWOMEN ,TECHNOLOGICAL innovations ,ENTREPRENEURSHIP ,FINANCIAL management - Abstract
This manuscript has set out the key issues connected to entrepreneurship in the framework of its connection with rustic area growth. The investigation seeks to identify determinants of rural entrepreneurship and the atmosphere encouraging its development. The policy needed to form this good environment has been discussed here. The conclusion is that in order to step up rural development in rustic rural areas, entrepreneurship must be encouraged. The entrepreneurial direction in rustic areas is based on invigorating local entrepreneurial capacity and successful development of innovative companies. This in turn would create jobs and add financially viable value to an area, while retaining scare funds within the community. [ABSTRACT FROM AUTHOR]
- Published
- 2021
- Full Text
- View/download PDF
23. Public Awareness and Education Programme for Landslide Management and Evaluation Using a Social Research Approach to Determining 'Acceptable Risk' and 'Tolerable Risk' in Landslide Risk Areas in Malaysia (IPL-194, IPL-207)
- Author
-
Rashid Ahmad, Ab, Amin, Zainal Arsad Md, Abdullah, Che Hassandi, Ngajam, Siti Zarina, Sassa, Kyoji, editor, Mikoš, Matjaž, editor, and Yin, Yueping, editor
- Published
- 2017
- Full Text
- View/download PDF
24. Efficacy and Safety of Ixekizumab Through 5 Years in Moderate-to-Severe Psoriasis: Long-Term Results from the UNCOVER-1 and UNCOVER-2 Phase-3 Randomized Controlled Trials.
- Author
-
Leonardi, Craig, Reich, Kristian, Foley, Peter, Torii, Hideshi, Gerdes, Sascha, Guenther, Lyn, Gooderham, Melinda, Ferris, Laura K., Griffiths, Christopher E. M., ElMaraghy, Hany, Crane, Heidi, Patel, Himanshu, Burge, Russel, Gallo, Gaia, Shrom, David, Leung, Ann, Lin, Chen-Yen, and Papp, Kim
- Subjects
- *
PSORIASIS , *MONOCLONAL antibodies , *SKIN diseases , *QUALITY of life , *ADVERSE health care events - Abstract
Introduction: Ixekizumab, a high-affinity monoclonal antibody that selectively targets interleukin-17A, is approved for treatment of moderate-to-severe plaque psoriasis. Our objective was to evaluate the long-term efficacy and safety of ixekizumab in moderate-to-severe plaque psoriasis through 5 years. Methods: Data were integrated from the UNCOVER-1 and UNCOVER-2, randomized, double-blinded, phase-3 trials. Patients who continuously received the labeled ixekizumab dose, were static Physician's Global Assessment (sPGA) (0,1) responders at Week 12 and completed 60 weeks of treatment could enter the long-term extension (LTE) period. Patients could escalate to every-2-week dosing per investigator opinion. Efficacy and health outcomes included proportion of patients achieving Psoriasis Area and Severity Index (PASI) 75/90/100, sPGA (0,1) and (0), absolute PASI ≤ 5/ ≤ 3/ ≤ 2/ ≤ 1 and Dermatology Life Quality Index (DLQI) (0,1). Results exclude patients who escalated to every-2-week dosing. A modified non-responder imputation method was used to account for missing data. Supplemental analyses include patients who escalated to every-2-week dosing and observed and multiple imputation results. Exposure-adjusted safety outcomes are also reported. Results: Of 206 patients who entered the LTE periods, 172 completed treatment. At Week 60, PASI 75/90/100 responses were 94.7%, 85.0% and 62.1%, respectively, and at year 5 were 90.3%, 71.3% and 46.3%, respectively. Similarly, meaningful responses were achieved for the other efficacy and health measures. Among patients with PASI 100 through 5 years, 92% achieved DLQI (0,1), indicating no impact of skin disease on quality of life. During the LTE period, exposure-adjusted incidence rates were 31.4 per 100 patient-years for treatment-emergent adverse events and 6.8 per 100 patient-years for serious adverse events. No deaths were reported. No new or unexpected safety findings were noted. Conclusions: The results demonstrate 80 mg ixekizumab maintains long-term efficacy and a safety profile consistent with previous data in patients with moderate-to-severe plaque psoriasis through 5 years of treatment. Trial Registration: ClinicalTrials.gov identifier, UNCOVER-1: NCT01474512, UNCOVER-2: NCT01597245. [ABSTRACT FROM AUTHOR]
- Published
- 2020
- Full Text
- View/download PDF
25. 面向养护便捷性的在役连拱隧道中墙病害维修方法及应用.
- Author
-
李羽婷 and 王海洋
- Abstract
Copyright of Guangdong Architecture Civil Engineering is the property of Guangdong Architecture Civil Engineering Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
- Published
- 2021
- Full Text
- View/download PDF
26. 不同群落类型土壤惰性碳含量特征与维持机制.
- Author
-
张玲, 张东来, 毛子军, and 丁一阳
- Subjects
- *
CARBON in soils , *MOUNTAIN soils , *SOIL moisture , *FOREST degradation , *MOUNTAIN forests , *SOIL density , *CARBON cycle , *MOUNTAIN ecology - Abstract
In order to study the effective management and scientific evaluation of soil carbon China forest ecosystem of soil carbon dynamic trend of library and its function and position in the global carbon cycles,sequence method is used to study the different community types recalcitrant organic carbon and maintains of Xiaoxing’an mountains degraded forest ecosystem. The results were the recalcitrant organic carbon of broadleaved Korean pin forests was the highest,followed by the spruce fir forest,and the Quercus mongolica forest was the least. The recalcitrant organic carbon had a significant linear positive correlation with soil moisture content and soil capillary porosity,and a significant linear negative correlation with soil bulk density. There was a significant linear positive correlation between soil recalcitrant organic carbon and soil total nitrogen in Pinus Koraiensis,Betula platypylla,Betula davurica. There was a significant linear negative correlation between soil total phosphorus and inert carbon content in Betula platypylla,Betula davurica forest and Quercus mongolica Fisch forest. There was an exponential relationship between the soil inert carbon content and the total potassium content in Pinus Koraiensis and Betula costata Trautv forests,and a significant linear negative correlation was found between the soil inert carbon content and the total potassium content in Betula platypylla,Picea jezoensis,Quercus mongolica,Betula davurica forest. Conclusion: different community types showed significant differences in the recalcitrant carbon content of soil,and the factors regulating the accumulation and maintenance of recalcitrant carbon in soil,community types and soil physical and chemical properties. The results of this study can provide scientific reference for accurately predicting the carbon sink dynamics and carbon sequestration benefit evaluation of degraded forest ecosystem in the Xiaoxing ’an mountains of China under the background of global change. [ABSTRACT FROM AUTHOR]
- Published
- 2019
27. THE IMPACT OF ENVIRONMENTAL PARAMETERS AND MAINTENANCE ON THE COMPRESSED MEDICAL AIR QUALITY.
- Author
-
MAJSTOROVIĆ, Aleksandar, TODIĆ, Mladen, ILIĆ, Predrag, ERIĆ, Ljiljana, VUKAJLOVIĆ, Dijana, and ĆULIBRK, Branka
- Subjects
- *
AIR quality , *COMPRESSED air , *ENVIRONMENTAL impact analysis - Abstract
Compressed medical air1 must meet certain criteria defined by European standard EN 120212, it shouldn't have any flavours or smell (odour). During filling bottle of breathing apparatus cylinders, it should be taken into account that vehicle exhaust gases, vapours of hazardous liquids, smoke and other harmful substances are not in the vicinity of the suction pipe cause they may get inside the cylinder of breathing apparatus and with their presence disrupt the microclimate (strictly defined parameters of medical air) and directly endanger the user. This isn't the case with cylinders which are the subject of this research. However, with physical-chemical and microbiological results samples of CMA, it can be said with responsibility that the user of the bottle / cylinder for the isulation devices did not comply the above when charging them with the CMA nor did it replace the filters of the high-pressure compressor in accordance with the manufacturer's instructions. This directly threatened his own health, but also the health of other users. Irresponsibility in maintain compressors of high-pressure, brought to creation of gram-positive bacterias and mildews as well as strain of pathogenic bacterias in CMA inside of the bottle/cylinder. The metabolism of the bacterias inside of the bottle/cylinder also reflected on the physicalchemical characteristics of CMA. [ABSTRACT FROM AUTHOR]
- Published
- 2018
28. Hjärtsviktspatienters upplevelser av vad som främjar egenvård : En litteraturöversikt
- Author
-
Rashica, Gresa, Varivodova-Johansson, Anastasia, Rashica, Gresa, and Varivodova-Johansson, Anastasia
- Abstract
Bakgrund: Hjärtsvikt är en kronisk folksjukdom som globalt drabbar cirka 26 miljoner årligen med stigande incidens. Sjukdomens symptom påverkar patientens förmåga till att upprätthålla sin egenvård som resulterar i försämrad livskvalitet. Egenvård är en stor och viktig del av patientens behandling och vardag. Sjuksköterskans uppgift är att informera och stötta för att främja patientens egenvård. Därför är det relevant att sjuksköterskan har kunskap om patientens upplevelse av främjande egenvård. Syfte: Syftet var att beskriva hjärtsviktspatienters upplevelser av vad som främjar egenvård. Metod: En litteraturöversikt med kvalitativ design och induktiv ansats genomfördes. Tolv vetenskapliga artiklar analyserades med Fribergs fem steg. Resultat: Fem subteman formade två teman. Att ha socialt nätverk och att hitta motivation formade stöd och motivation. Att känna engagemang till behandling, att ha tillräckligt med information och att ha tillgång till hjälpmedel formade sjukdomsinsikt. Slutsats: Resultatet visade att det fanns främjande upplevelser av egenvård hos patienter. Stöd och motivation var centrala komponenter för att underhålla egenvård. För att främja egenvård framkom det också att sjukdomsinsikt hade en betydande roll. Engagemang till behandling, information och symtomövervakning med diverse hjälpmedel bidrog till ökad sjukdomsinsikt och goda upplevelser av egenvård., Background: Heart failure is a chronic disease that globally affecting approximately 26 million yearly with increasing incidence. The symptoms of the disease affects the patient's ability to maintain their self-care, resulting in a reduced life quality. Self-care is a large and important part of the patient’s treatment and everyday life. The nurse’s job is to inform and support the patient to promote self-care. Therefore, it is relevant that the nurse has knowledge about the patient’s experience of self-care. Aim: The aim was to describe heart failure patients' experiences of what promotes self-care. Method: A literature review with qualitative design and inductive approach was conducted. Twelve scientific articles were analyzed with Friberg’s five-step. Results: Five subthemes formed two themes. To have social network and to find motivation, formed support and motivation. To feel committed to treatment, to have enough information and to have access to devices, formed disease awareness. Conclusion: The results showed that there were promoting experiences of self-care in patients. Support and motivation were central components for maintaining self-care. To promote self-care, it were also found that disease awareness played an important role. Commitment to treatment, information and monitoring of symptoms with different devices contributed to increased disease awareness and good experiences of self-care.
- Published
- 2022
29. 'The end of the Beginning'
- Author
-
Francis, Ross, Mathew, Joseph, editor, Kennedy, Jim, editor, Ma, Lin, editor, Tan, Andy, editor, and Anderson, Deryk, editor
- Published
- 2006
- Full Text
- View/download PDF
30. Mimicry and Shame in Naipaul's <italic>The Mimic Men</italic> and Desai's <italic>The Inheritance of Loss</italic>.
- Author
-
Filipovic, Zlatan
- Subjects
DIASPORA ,HISTORY - Abstract
Reflecting on the affective nature of diasporic experience, the essay begins by developing Arendt's understanding of displacement as a temporal disjunction of being caught between the claims of the past and the exigencies of the present. The impossibility of salvaging the past against the often stifling imperatives of the present that she accounts for in her essay ‘We Refugees’ is, however, also what produces affective economies in the diasporic subject that I argue are crucial to diasporic identity formation. In this respect, I focus on shame, which I see as an affective residue of the unsalvageable past in the experience of displacement. In order to determine and further develop the significance of shame for diasporic subject formation, this essay will consider its impact on subjectivity in a comparative close reading of two contemporary novels, V. S. Naipaul's
The Mimic Men and Kiran Desai'sThe Inheritance of Loss , both of which manifest the elision of the past in diasporized subjects and the movement towards strategies of identification articulated in mimicry. Mimicry, seen in Fanon's rather than Bhabha's terms, as a disavowal of the past, fails, however, to provide a viable strategy of identification for a diasporic subject in the novels that testify rather to the affective cost of our incumbent efforts to start anew. [ABSTRACT FROM AUTHOR]- Published
- 2017
- Full Text
- View/download PDF
31. Buffering effects of soil seed banks on plant community composition in response to land use and climate
- Author
-
Gareth K. Phoenix, Rob H. Marrs, Hans Van Calster, Richard Chevalier, Bryndís Marteinsdóttir, Hans Jacquemyn, Hans Henrik Bruun, Per Milberg, Inger Auestad, Renée M. Bekker, Sofía Basto, Guillaume Decocq, Robin J. Pakeman, Vigdis Vandvik, Rein Kalamees, Markus Wagner, Ulf Grandin, Ken Thompson, Jan Plue, Inger Elisabeth Måren, Alistair G. Auffret, Małgorzata Jankowska-Błaszczuk, Marcus A. Koch, Martin Hermy, Anna Jakobsson, and Conservation Ecology Group
- Subjects
0106 biological sciences ,Soil seed bank ,bank ,land‐ ,DIVERSITY ,Biodiversity ,Environmental Sciences & Ecology ,use change ,010603 evolutionary biology ,01 natural sciences ,Ecology and Environment ,soil seed ,land-use change ,forest ,SPACE ,Ecosystem ,Land use, land-use change and forestry ,LONGEVITY ,Ecology, Evolution, Behavior and Systematics ,forest grassland ,Global and Planetary Change ,Science & Technology ,Ecology ,SPECIES RICHNESS ,010604 marine biology & hydrobiology ,Global warming ,land‐use change ,Plant community ,Miljövetenskap ,EXTINCTION RISK ,TIME ,MAINTAIN ,Europe ,Geography, Physical ,MAINTENANCE ,climate change ,Geography ,Physical Geography ,Habitat ,Physical Sciences ,SIMILARITY ,PATTERNS ,plant biodiversity ,soil seed bank ,Species richness ,grassland ,Life Sciences & Biomedicine ,Environmental Sciences - Abstract
Aim\ud \ud Climate and land use are key determinants of biodiversity, with past and ongoing changes posing serious threats to global ecosystems. Unlike most other organism groups, plant species can possess dormant life‐history stages such as soil seed banks, which may help plant communities to resist or at least postpone the detrimental impact of global changes. This study investigates the potential for soil seed banks to achieve this.\ud \ud \ud \ud Location\ud \ud Europe.\ud \ud \ud \ud Time period\ud \ud 1978–2014.\ud \ud \ud \ud Major taxa studied\ud \ud Flowering plants.\ud \ud \ud \ud Methods\ud \ud Using a space‐for‐time/warming approach, we study plant species richness and composition in the herb layer and the soil seed bank in 2,796 community plots from 54 datasets in managed grasslands, forests and intermediate, successional habitats across a climate gradient.\ud \ud \ud \ud Results\ud \ud Soil seed banks held more species than the herb layer, being compositionally similar across habitats. Species richness was lower in forests and successional habitats compared to grasslands, with annual temperature range more important than mean annual temperature for determining richness. Climate and land‐use effects were generally less pronounced when plant community richness included seed bank species richness, while there was no clear effect of land use and climate on compositional similarity between the seed bank and the herb layer.\ud \ud \ud \ud Main conclusions\ud \ud High seed bank diversity and compositional similarity between the herb layer and seed bank plant communities may provide a potentially important functional buffer against the impact of ongoing environmental changes on plant communities. This capacity could, however, be threatened by climate warming. Dormant life‐history stages can therefore be important sources of diversity in changing environments, potentially underpinning already observed time‐lags in plant community responses to global change. However, as soil seed banks themselves appear, albeit less, vulnerable to the same changes, their potential to buffer change can only be temporary, and major community shifts may still be expected.
- Published
- 2020
32. Efficacy and Safety of Ixekizumab Through 5 Years in Moderate-to-Severe Psoriasis: Long-Term Results from the UNCOVER-1 and UNCOVER-2 Phase-3 Randomized Controlled Trials
- Author
-
David Shrom, Melinda Gooderham, Craig L. Leonardi, Himanshu Patel, Hideshi Torii, Chen-Yen Lin, Kim A. Papp, Russel Burge, Christopher E.M. Griffiths, Laura K. Ferris, Ann Leung, Lyn Guenther, Kristian Reich, Peter Foley, Gaia Gallo, Sascha Gerdes, H. Elmaraghy, and Heidi Crane
- Subjects
Quality of life ,medicine.medical_specialty ,Ixekizumab ,Dermatology ,law.invention ,030207 dermatology & venereal diseases ,03 medical and health sciences ,0302 clinical medicine ,Randomized controlled trial ,law ,Psoriasis Area and Severity Index ,Psoriasis ,Internal medicine ,lcsh:Dermatology ,medicine ,Dosing ,Long-term safety ,Adverse effect ,Long-term efficacy ,5 years ,Original Research ,business.industry ,Dermatology Life Quality Index ,lcsh:RL1-803 ,medicine.disease ,Maintain ,030220 oncology & carcinogenesis ,business - Abstract
Introduction Ixekizumab, a high-affinity monoclonal antibody that selectively targets interleukin-17A, is approved for treatment of moderate-to-severe plaque psoriasis. Our objective was to evaluate the long-term efficacy and safety of ixekizumab in moderate-to-severe plaque psoriasis through 5 years. Methods Data were integrated from the UNCOVER-1 and UNCOVER-2, randomized, double-blinded, phase-3 trials. Patients who continuously received the labeled ixekizumab dose, were static Physician’s Global Assessment (sPGA) (0,1) responders at Week 12 and completed 60 weeks of treatment could enter the long-term extension (LTE) period. Patients could escalate to every-2-week dosing per investigator opinion. Efficacy and health outcomes included proportion of patients achieving Psoriasis Area and Severity Index (PASI) 75/90/100, sPGA (0,1) and (0), absolute PASI ≤ 5/ ≤ 3/ ≤ 2/ ≤ 1 and Dermatology Life Quality Index (DLQI) (0,1). Results exclude patients who escalated to every-2-week dosing. A modified non-responder imputation method was used to account for missing data. Supplemental analyses include patients who escalated to every-2-week dosing and observed and multiple imputation results. Exposure-adjusted safety outcomes are also reported. Results Of 206 patients who entered the LTE periods, 172 completed treatment. At Week 60, PASI 75/90/100 responses were 94.7%, 85.0% and 62.1%, respectively, and at year 5 were 90.3%, 71.3% and 46.3%, respectively. Similarly, meaningful responses were achieved for the other efficacy and health measures. Among patients with PASI 100 through 5 years, 92% achieved DLQI (0,1), indicating no impact of skin disease on quality of life. During the LTE period, exposure-adjusted incidence rates were 31.4 per 100 patient-years for treatment-emergent adverse events and 6.8 per 100 patient-years for serious adverse events. No deaths were reported. No new or unexpected safety findings were noted. Conclusions The results demonstrate 80 mg ixekizumab maintains long-term efficacy and a safety profile consistent with previous data in patients with moderate-to-severe plaque psoriasis through 5 years of treatment. Trial Registration ClinicalTrials.gov identifier, UNCOVER-1: NCT01474512, UNCOVER-2: NCT01597245. Electronic Supplementary Material The online version of this article (10.1007/s13555-020-00367-x) contains supplementary material, which is available to authorized users.
- Published
- 2020
33. EDUCAȚIA PRENATALĂ DIN PERSPECTIVA EDUCAȚIEI PERMANENTE.
- Author
-
PAPP, Eniko Gabriela, PESCARI, Tatiana-Ana, POPESCU, Teodora Liana, BAKO, Aliz Tunde, and SZASZ, Simona
- Abstract
Copyright of Studia Universitatis Vasile Goldis, Physical Education & Physical Therapy Series is the property of Vasile Goldis University Press and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
- Published
- 2016
34. Application of virtual reality to simulation in equipment maintenance.
- Author
-
Bin Shen, Tao Wang, Jihua Zhao, and Zhendong Tang
- Abstract
Along with science technical development, complications and technology content of machine equipments are more and higher and renew speed of it is more and more quickly, and this give a tremendous challenge to the training of maintain of machine equipments. It is have great significance to the maintaining of machine equipments guarantee by Appling the technique of virtual realistic at the machine equipments, developing the maintain training system in VR. It is personnel of important assurance to develop qualified maintain. It effectively solved problems about equipments of maintain and training whose structure complicated, price expensive and restrict training place and low efficiency. Therefore, this paper shows a certain machine equipments which is an object and designed to imitate to really maintain system. It provides an effective solution for the maintaining of machine equipments training. [ABSTRACT FROM PUBLISHER]
- Published
- 2012
- Full Text
- View/download PDF
35. How to maintain strong marital bond?
- Author
-
Tenginkai, Gouri Shankar, Chadha, N. K., and Sharma, Chavi Bhargava
- Subjects
- *
MARITAL relations , *SPOUSES' legal relationship , *MARITAL satisfaction , *MARRIED people , *MARITAL quality , *EMPATHY , *EMOTION regulation - Abstract
Bonding is most important to achieve marital success. Empathy plays a vital role in enhancing emotional closeness between the married partners. It's one of the most important form of human psychotherapy and has contributed in enhancing the growth in most forms of relationships. Communication is the key to happy marriage and the emotional layer of communication is most vital for married couples. Good emotional communication is the foundation that enhances problem-solving skills, resulting in strong marital bonding between the spouses. In the past, marital bond between the spouses were stronger, as marriage then was never a source of deriving happiness. In the recent times, the new modern era marriages are no more about strong marital bond, as they only strive for individual happiness, self goals and self centered desires and aspirations. Emotional equality between the married partners that include qualities like love, sympathy, loyalty and patience; are required to achieve lasting marital bond. Marriage is a bond between two equal partners, this understanding and mental maturity will not allow dominance of either partner and will strengthen the marital bond. As Mahatma Gandhi rightly said that marriage is a partnership and not a hierarchical arrangement. To achieve the status of marital bond being stronger than blood bond, the married couples must strive for an emotional bond between them. Your marriage is the most important relationship you will ever have, and marriage is an ultimate bond between two partners, and hence its very importance to keep up the promise of 'Till death do us apart' that the couples made while they got married, to achieve and win an everlasting strong marital bond. [ABSTRACT FROM AUTHOR]
- Published
- 2017
36. Polyploidy: A Biological Force From Cells to Ecosystems
- Author
-
Yves Van de Peer, Donald T. Fox, Douglas E. Soltis, Pamela S. Soltis, and Tia-Lynn Ashman
- Subjects
endoreplication ,Biodiversity ,Biology ,HEPATOCYTES ,Article ,MECHANISMS ,Polyploidy ,03 medical and health sciences ,0302 clinical medicine ,Polyploid ,Stress, Physiological ,REGENERATION ,Gene duplication ,Endoreduplication ,PLANTS ,cellular polyploidy ,Regeneration (ecology) ,ENDOCYCLES ,Ecosystem ,polyploidy ,Organism ,030304 developmental biology ,Grand Challenges ,0303 health sciences ,Genome ,ANEUPLOIDY ,Biology and Life Sciences ,Cell Biology ,BARRIER ,CANCER ,organismal polyploidy ,MAINTAIN ,Evolutionary biology ,whole-genome duplication ,Biocomplexity ,PATTERNS ,030217 neurology & neurosurgery - Abstract
Polyploidy, resulting from the duplication of an organism’s or a cell’s entire genome, greatly affects genes and genomes, cells and tissues, organisms and even entire ecosystems. Despite the wide-reaching importance of polyploidy, communication across disciplinary boundaries to identify common themes at different scales has been almost non-existent. However, a critical need remains to understand commonalities that derive from shared polyploid cellular processes across organismal diversity, levels of biological organization, and fields of inquiry – from biodiversity and biocomplexity to medicine and agriculture. Here, we review the current understanding of polyploidy at the organismal and sub-organismal levels, identify shared research themes and elements, and propose new directions to integrate research on polyploidy toward confronting interdisciplinary grand challenges of the 21(st) century.
- Published
- 2020
- Full Text
- View/download PDF
37. Hizmet İşletmelerinde Performans Algısının Ölçümü: Kapadokya Bölgesi Örneği Measurement of Performance Signal in Service Operations: Cappadocia Region Example
- Author
-
Şükran Güngör Tanç, Ahmet Tanç, and Nurten Örgün
- Subjects
business.industry ,media_common.quotation_subject ,Performance ,Anova test ,Flexibility (personality) ,Context (language use) ,Yenilik ,lcsh:Business ,Maintain ,Perception of Performance ,Test (assessment) ,Performans Algısı ,Competition (economics) ,Esneklik ,Perception ,Süreklilik ,Business ,Marketing ,Flexibility ,Innovation ,lcsh:HF5001-6182 ,Accommodation ,Performans ,Tourism ,media_common - Abstract
Günümüzde yoğun rekabet şartlarında faaliyet gösteren işletmelerin performans analizi yapmaları büyük önem taşımaktadır. Performans analizleri genellikle periyodik dönemler halinde yapılmaktadır. Buna ek olarak bazı durumlarda performans algısında ki değişikliklerle performans analizi yapılabilmektedir. İşletmelerde ki performans analizinin amacı diğer tüm ticari işletmeler de olduğu gibi otel ve restoran işletmelerinin karlılık düzeyini yükseltmektir. Bu nedenle işletmeler için olağan ve olan dışı yapılan performans analizleri ve performans algısı büyük önem taşımaktadır. Bu çalışmada Türkiye'de turizm yoğun olarak bulunduğu Nevşehir ilinde faaliyet gösteren otel ve restoran işletmelerinde ki üst düzey çalışanlara anket uygulanmıştır. Katılımcılara, anket formunda performansı etkileyen yenilik, süreklilik ve esneklik ile ilgili sorular yöneltilmiştir. Cevapları analiz etmek için parametrik testlerden "t" testi ve ANOVA testi kullanılmıştır. Analiz sonuçlarına göre konaklama ve yiyecek-içecek işletmelerinde ki yöneticilerin demografik özelliklerine göre işletme performansı algılarında farklılık olduğu belirlenmiştir. Today, performance analysis of companies operating under intense competition conditions is very important. Performance analyzes are usually carried out periodically, and in some cases performance analysis can be performed depending on performance perception. The main purpose of working in this context is to measure performance perceptions of hotel and restaurant businesses. The study, which operates in Turkey's Cappadocia region as a busy tourist hotel which is built on and senior employees in the restaurant business. Participants were directed to expressing perceptions of innovation, continuity, and flexibility that affect performance. The "t" test and the ANOVA test were used to analyze the answers. According to the results of the analysis, it was determined that there is a difference in the perception of the management performance according to the demographic characteristics of the managers operating in the accommodation and catering businesses.
- Published
- 2018
38. Impact of the ALMS and MAINTAIN trials on the management of lupus nephritis.
- Author
-
Morris, Heather K., Canetta, Pietro A., and Appel, Gerald B.
- Subjects
- *
LUPUS nephritis , *DISEASE relapse , *CYCLOPHOSPHAMIDE , *ORAL medicine , *CLINICAL trials , *DRUG dosage , *THERAPEUTICS - Abstract
Current treatment of lupus nephritis consists of both induction and maintenance therapy, with the latter being designed to consolidate remissions and prevent relapses. Long-term maintenance treatment with intravenous cyclophosphamide was effective but associated with considerable toxicity. A small but well-designed controlled trial found that for post-induction maintenance therapy, both oral mycophenolate mofetil (MMF) and oral azathioprine were superior in efficacy and had reduced toxicity than a regimen of continued every third month intravenous cyclophosphamide. Although these oral agents were rapidly accepted and utilized as maintenance medications, their usage was based on scant evidence and there were no comparisons between the two. Recently, two relatively large, randomized, well-controlled, multicenter trials dealing with maintenance therapy for severe lupus nephritis have been completed. The Aspreva Lupus Management Study (ALMS) maintenance and MAINTAIN nephritis trials provide important information regarding the comparative efficacy and safety of MMF and azathioprine as maintenance therapies, as well as information on the effect of dosage and duration of treatment with these agents. [ABSTRACT FROM AUTHOR]
- Published
- 2013
- Full Text
- View/download PDF
39. Spårdjup i asfaltsbeläggningar
- Author
-
Svensk, Emil and Svensk, Emil
- Abstract
I Sverige idag finns ett statligt vägnät som finansieras och underhålls av de Svenska myndigheterna genom Trafikverket. På Trafikverkets avdelning för underhåll planeras och genomförs underhållsåtgärder för att vägarnas standard ska uppfylla de beslutande kraven som finns. En av de dimensionerande faktorerna vid underhåll av asfaltsvägar är spårdjup, spårdjupen får inte överstiga den specifika underhållsstandarden som finns eftersom om det sker ökar olycksrisken och en försämrad framkomlighet kan uppstå. Ett av syftena med detta examensarbete är att undersöka om det går att förutse var och varför asfaltsbeläggningar inte uppfyller underhållsstandarden som finns. Metoden som används grundar sig i en analys av mätdata som inhämtats genom laserskanning av vägytan med hjälp av en mätbil. Datan presenteras i form av grafer och figurer i Trafikverkets öppna webbportal PMSV3, graferna och figurerna har analyserats för att sedan utgöra resultatet och slutsatserna i arbetet. Resultatet som framgick stämmer som helhet överens med grundinställningen innan arbetet påbörjades, att det går att se en indikation efter några år vart beläggningen kommer att överstiga maximalt spårdjup enligt underhållsstandarden. Men att förutse om och var beläggningen kommer försämras först och mest är svårare i ett tidigt skede. Arbetets slutsatser har bidragit till att flera förslag på fortsatta arbeten har föreslagits, vilket får arbetet att anses lyckat., In Sweden today, there is a state road network that is financed and maintained by the Swedish authorities through the Swedish Transport Administration. At the Swedish Transport Administration maintenance department, maintenance measures are planned and implemented to ensure that the standards of the roads meet the decision requirements that exist. One of the dimension factors for maintenance of asphalt roads is rut depth, the groove depth must not exceed the specific maintenance standard that exists because, if this happens, the accident risk increases One of the purposes of this thesis is to investigate whether it is possible to predict where and why asphalt pavements do not meet the maintenance standard that exists. The result which appeared to be in agreement with the basic attitude before the work was started, that it is possible to see an indication after a few years where the occupancy will exceed the maintenance standard But to predict if and where the asphalt coating will deteriorate first and most is more difficult at an early stage The work's conclusions have contributed to several ideas for further work being proposed, which makes the work to be considered successful
- Published
- 2019
40. MAINTENANCE COMMITMENTS FOR MONOPOLIZED GOODS.
- Author
-
Pu-yan Nie
- Subjects
MONOPOLIES ,MAINTENANCE costs ,CORPORATE profits ,WARRANTY ,ELEVATORS ,COMPUTERS - Abstract
The article persents a study that investigated the monopoly firms' guarantee for items that require high maintenance cost which include elevators, computers and televisions and its relation to the firm's profit. The study discovered no correlation between the guarantee pattern on the monopoly firm's profit as long as all both consumers and monopolists are well-informed. It furthers states the exaggeration of the firm of the product's quality without meeting the warranty promised.
- Published
- 2012
- Full Text
- View/download PDF
41. Ability to Control Persistent Asthma in Obese Versus Non-Obese Children Enrolled in an Asthma-Specific Disease Management Program (Breathmobile).
- Author
-
Kwong, K. Y., Rhandhawa, I., Saxena, J., Morphew, T., and Jones, C. A.
- Subjects
- *
ASTHMA in children , *JUVENILE diseases , *DISEASE management , *CHILDHOOD obesity - Abstract
To determine if asthma control was more difficult to achieve in obese versus non-obese asthmatic children, retrospective analysis was performed on obese and non-obese Los Angeles inner-city children (2 to 18 years of age) with persistent asthma. No difference in time required to achieve control of asthma, ability to maintain control of asthma, baseline pulmonary functions, and number of controllers prescribed was found between the two groups. We conclude that in a Los Angeles inner-city pediatric population, obesity is not a factor in the ability to control asthma. [ABSTRACT FROM AUTHOR]
- Published
- 2006
- Full Text
- View/download PDF
42. The Tradition of Ye Gyan Zin in Myanmar
- Author
-
Mon Mon Aung
- Subjects
Ye Gyan Zin ,case study method ,Social Science ,maintain ,the tradition - Abstract
Water is essential for all life. A Myanmar saying goes that humans can 'live seven days without rice, and one morning without water'. We continuously need water in our surrounding to support our lives. This is why Myanmar people take care to place many waterpots of cool drinking water ye gyan zin for the public. When ancient travellers in Myanmar went to one village or another, they were often thirsty and tired. So villagers would place water pots under the tree or in the public rest house along the route. The research questions this paper addresses are 1 when did Ye Gyan Zin use in Myanmar And 2 what is the impact of water on Myanmar culture This problem will be solved by case study method. This paper will be focus how the water pot traditions are maintained in Myanmar. Mon Mon Aung "The Tradition of Ye Gyan Zin in Myanmar" Published in International Journal of Trend in Scientific Research and Development (ijtsrd), ISSN: 2456-6470, Volume-3 | Issue-4 , June 2019, URL: https://www.ijtsrd.com/papers/ijtsrd21449.pdf Paper URL: https://www.ijtsrd.com/humanities-and-the-arts/social-science/21449/the-tradition-of-ye-gyanzin-E1%80%9B%E1%80%B1%E1%80%81%E1%80%BB%E1%80%99%E1%80%BA%E1%80%B8%E1%80%85%E1%80%84%E1%80%BA-in-myanmar/mon-mon-aung
- Published
- 2019
43. Rut depth in asphalt surface
- Author
-
Svensk, Emil
- Subjects
asfaltsbeläggning ,underhåll ,Spårdjup ,Byggproduktion ,maintain ,asphalt surface ,rut depth ,Construction Management - Abstract
I Sverige idag finns ett statligt vägnät som finansieras och underhålls av de Svenska myndigheterna genom Trafikverket. På Trafikverkets avdelning för underhåll planeras och genomförs underhållsåtgärder för att vägarnas standard ska uppfylla de beslutande kraven som finns. En av de dimensionerande faktorerna vid underhåll av asfaltsvägar är spårdjup, spårdjupen får inte överstiga den specifika underhållsstandarden som finns eftersom om det sker ökar olycksrisken och en försämrad framkomlighet kan uppstå. Ett av syftena med detta examensarbete är att undersöka om det går att förutse var och varför asfaltsbeläggningar inte uppfyller underhållsstandarden som finns. Metoden som används grundar sig i en analys av mätdata som inhämtats genom laserskanning av vägytan med hjälp av en mätbil. Datan presenteras i form av grafer och figurer i Trafikverkets öppna webbportal PMSV3, graferna och figurerna har analyserats för att sedan utgöra resultatet och slutsatserna i arbetet. Resultatet som framgick stämmer som helhet överens med grundinställningen innan arbetet påbörjades, att det går att se en indikation efter några år vart beläggningen kommer att överstiga maximalt spårdjup enligt underhållsstandarden. Men att förutse om och var beläggningen kommer försämras först och mest är svårare i ett tidigt skede. Arbetets slutsatser har bidragit till att flera förslag på fortsatta arbeten har föreslagits, vilket får arbetet att anses lyckat. In Sweden today, there is a state road network that is financed and maintained by the Swedish authorities through the Swedish Transport Administration. At the Swedish Transport Administration maintenance department, maintenance measures are planned and implemented to ensure that the standards of the roads meet the decision requirements that exist. One of the dimension factors for maintenance of asphalt roads is rut depth, the groove depth must not exceed the specific maintenance standard that exists because, if this happens, the accident risk increases One of the purposes of this thesis is to investigate whether it is possible to predict where and why asphalt pavements do not meet the maintenance standard that exists. The result which appeared to be in agreement with the basic attitude before the work was started, that it is possible to see an indication after a few years where the occupancy will exceed the maintenance standard But to predict if and where the asphalt coating will deteriorate first and most is more difficult at an early stage The work's conclusions have contributed to several ideas for further work being proposed, which makes the work to be considered successful
- Published
- 2019
44. Oxygen ion conducting materials
- Author
-
Carter, J [Bolingbrook, IL]
- Published
- 2003
45. Sensing mode atomic force microscope
- Author
-
Wang, Chengpu [Upton, NY]
- Published
- 2003
46. Liga developer apparatus system
- Author
-
Christenson, Todd [Albuquerque, NM]
- Published
- 2003
47. Calibration of fluorescence resonance energy transfer in microscopy
- Author
-
Yang, Mary [San Jose, CA]
- Published
- 2002
48. Thermoelectric materials: ternary penta telluride and selenide compounds
- Author
-
Sharp, Jeffrey [Richardson, TX]
- Published
- 2002
49. Carbon nanotubes on a substrate
- Author
-
Liu, Jun [West Richland, WA]
- Published
- 2002
50. Exhaust gas purification system for lean burn engine
- Author
-
Haines, Leland [Northville, MI]
- Published
- 2002
Catalog
Discovery Service for Jio Institute Digital Library
For full access to our library's resources, please sign in.