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5,121 results on '"MAP Kinase Kinase 4"'

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1. HIPK2-Mediated Transcriptional Control of NMDA Receptor Subunit Expression Regulates Neuronal Survival and Cell Death

2. CtBP impedes JNK- and Upd/STAT-driven cell fate misspecifications in regenerating Drosophila imaginal discs.

3. CtBP impedes JNK- and Upd/STAT-driven cell fate misspecifications in regenerating Drosophila imaginal discs

4. A sestrin-dependent Erk–Jnk–p38 MAPK activation complex inhibits immunity during aging

5. Conserved gatekeeper methionine regulates the binding and access of kinase inhibitors to ATP sites of MAP2K1, 4, and 7: Clues for developing selective inhibitors.

6. Serum Amyloid A Induces Inflammation, Proliferation and Cell Death in Activated Hepatic Stellate Cells.

7. The autoinhibited state of MKK4: Phosphorylation, putative dimerization and R134W mutant studied by molecular dynamics simulations

8. Two Hydrophobic Residues Can Determine the Specificity of Mitogen-activated Protein Kinase Docking Interactions*

9. Involvement of JNK and caspase activation in hoiamide A-induced neurotoxicity in neocortical neurons.

10. Mitochondrial MKP1 Is a Target for Therapy-Resistant HER2-Positive Breast Cancer Cells

11. The MEKK1 PHD ubiquitinates TAB1 to activate MAPKs in response to cytokines

12. ZPK/DLK and MKK4 Form the Critical Gateway to Axotomy-Induced Motoneuron Death in Neonates

13. Ethanol negatively regulates hepatic differentiation of hESC by inhibition of the MAPK/ERK signaling pathway in vitro.

14. Rapid degeneration of rod photoreceptors expressing self-association-deficient arrestin-1 mutant

15. Polyoxygenated cholesterol ester hydroperoxide activates TLR4 and SYK dependent signaling in macrophages.

16. Small-molecule inhibition of MAP2K4 is synergistic with RAS inhibitors in KRAS -mutant cancers.

17. Whole-genome analysis informs breast cancer response to aromatase inhibition

18. JNK pathway activation is controlled by Tao/TAOK3 to modulate ethanol sensitivity.

19. Insulin resistance in non-obese subjects is associated with activation of the JNK pathway and impaired insulin signaling in skeletal muscle.

20. Involvement of HSP90 in ischemic postconditioning-induced cardioprotection by inhibition of the complement system, JNK and inflammation

21. Regulation of the JNK pathway by TGF-beta activated kinase 1 in rheumatoid arthritis synoviocytes

22. CD40/TRAF1 decreases synovial cell apoptosis in patients with rheumatoid arthritis through JNK/NF-κB pathway

23. Raspberry and blackberry act in a synergistic manner to improve cardiac redox proteins and reduce NF-κB and SAPK/JNK in mice fed a high-fat, high-sucrose diet

24. Reviving human γδT cells from apoptosis induced by IL-12/18 via p-JNK inhibition

25. PCAT19 Regulates the Proliferation and Apoptosis of Lung Cancer Cells by Inhibiting miR-25-3p via Targeting the MAP2K4 Signal Axis

26. Heterogeneous expression of multiple putative patterning genes by single cells from the chick hindbrain.

27. ACT001 inhibits pituitary tumor growth by inducing autophagic cell death via MEK4/MAPK pathway

28. Bovine α-lactalbumin-derived peptides attenuate TNF-α-induced insulin resistance and inflammation in 3T3-L1 adipocytes through inhibiting JNK and NF-κB signaling

29. A small molecule targeting CHI3L1 inhibits lung metastasis by blocking IL‐13Rα2‐mediated JNK‐AP‐1 signals

30. MicroRNA‐210 repression facilitates advanced glycation end‐product (AGE)‐induced cardiac mitochondrial dysfunction and apoptosis via JNK activation

31. Advanced glycosylation end products inhibit the proliferation of bone-marrow stromal cells through activating MAPK pathway

32. Arrestin-3-Dependent Activation of c-Jun N-Terminal Kinases (JNKs).

33. Phosphorylation of RXRα mediates the effect of JNK to suppress hepatic FGF21 expression and promote metabolic syndrome

34. NT157 exerts antineoplastic activity by targeting JNK and AXL signaling in lung cancer cells

35. LncRNA HOTAIRM1 Involved in Nano NiO-Induced Pulmonary Fibrosis via Regulating PRKCB DNA Methylation-Mediated JNK/c-Jun Pathway

36. Apolipoprotein A-IV reduced metabolic inflammation in white adipose tissue by inhibiting IKK and JNK signaling in adipocytes

37. Study 6: Replication of Kan et al., 2010 (Nature)

38. Role of miR-27a in the regulation of cellular function via the inhibition of MAP2K4 in patients with asthma

39. Anti-inflammatory Effects of Empagliflozin and Gemigliptin on LPS-Stimulated Macrophage via the IKK/NF-κB, MKK7/JNK, and JAK2/STAT1 Signalling Pathways

40. Mobile element insertions and associated structural variants in longitudinal breast cancer samples

41. JNK/Elk1 signaling and PCNA protein expression in the brain of hibernating frog Pelophylax esculentus

42. Ghrelin attenuate cerebral microvascular leakage by regulating inflammation and apoptosis potentially via a p38 MAPK-JNK dependent pathway

43. TNFα enhances trovafloxacin-induced in vitro hepatotoxicity by inhibiting protective autophagy

45. Benzo[a]pyrene exposure promotes RIP1-mediated necroptotic death of osteocytes and the JNK/IL-18 pathway activation via generation of reactive oxygen species

46. EST12 regulates Myc expression and enhances anti-mycobacterial inflammatory response

47. miR-145-5p targets paxillin to attenuate angiotensin II-induced pathological cardiac hypertrophy via downregulation of Rac 1, pJNK, p-c-Jun, NFATc3, ANP and by Sirt-1 upregulation

48. DGG-100629 inhibits lung cancer growth by suppressing the NFATc1/DDIAS/STAT3 pathway

49. Phyllanthin inhibits MOLT‐4 leukemic cancer cell growth and induces apoptosis through the inhibition of AKT and JNK signaling pathway

50. A Dual Target-Directed Single Domain-Based Fusion Protein Against Interleukin-6 Receptor Decelerate Experimental Arthritis Progression Via Modulating JNK Expression

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