1. Genomic insight into the amino acid relations of the pea aphid, Acyrthosiphon pisum, with its symbiotic bacterium Buchnera aphidicola
- Author
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Wilson, A. C. C., Ashton, P. D., Calevro, Federica, Charles, H., Colella, Stefano, Febvay, G., Jander, G., Kushlan, P. F., Macdonald, S. J., Schwartz, J. F., Thomas, G. H., Douglas, A. E., Department of Biology [Miami], University of Miami [Coral Gables], Department of Biology [York], University of York [York, UK], Biologie Fonctionnelle, Insectes et Interactions (BF2I), Institut National de la Recherche Agronomique (INRA)-Institut National des Sciences Appliquées de Lyon (INSA Lyon), Institut National des Sciences Appliquées (INSA)-Université de Lyon-Institut National des Sciences Appliquées (INSA)-Université de Lyon, An algorithmic view on genomes, cells, and environments (BAMBOO), Inria Grenoble - Rhône-Alpes, Institut National de Recherche en Informatique et en Automatique (Inria)-Institut National de Recherche en Informatique et en Automatique (Inria)-Laboratoire de Biométrie et Biologie Evolutive - UMR 5558 (LBBE), Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Institut National de Recherche en Informatique et en Automatique (Inria)-VetAgro Sup - Institut national d'enseignement supérieur et de recherche en alimentation, santé animale, sciences agronomiques et de l'environnement (VAS)-Centre National de la Recherche Scientifique (CNRS)-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-VetAgro Sup - Institut national d'enseignement supérieur et de recherche en alimentation, santé animale, sciences agronomiques et de l'environnement (VAS)-Centre National de la Recherche Scientifique (CNRS), Boyce Thompson Institute [Ithaca], Cornell University [New York], BBSRC, ANR BB/F005342/1, USDA 2005-35604-15446, University of Miami Start-up Funds, Sarkaria Institute for Insect Physiology and Toxicology, University of Miami Honors Summer Research Program, Biotechnology and Biological Sciences Research Council BB/F005342/1, Université de Lyon-Institut National des Sciences Appliquées (INSA)-Université de Lyon-Institut National des Sciences Appliquées (INSA), and Cornell University
- Subjects
MESH: Amino Acids ,MESH: Buchnera ,Genome, Insect ,ACYRTHOSIPHON PISUM ,MESH: Peas ,MESH: Genome, Bacterial ,Models, Biological ,GENOME ANNOTATION ,HEMIPTERA ,Bacterial Proteins ,Buchnera ,MESH: Transaminases ,MESH: Insect Proteins ,Animals ,MESH: Animals ,Amino Acids ,MESH: Bacterial Proteins ,Transaminases ,GENOME EVOLUTION ,MESH: Genetic Complementation Test ,MESH: Symbiosis ,MESH: Genome, Insect ,Genetic Complementation Test ,ESSENTIAL AMINO ACID ,SYMBIOSIS ,Peas ,MESH: Models, Biological ,food and beverages ,biochemical phenomena, metabolism, and nutrition ,BUCHNERA APHICOLA ,Aphids ,GENOMIC COMPLEMENTARITY ,Insect Proteins ,AMINO ACID METABOLISM ,MESH: Aphids ,Genome, Bacterial ,[SDV.EE.IEO]Life Sciences [q-bio]/Ecology, environment/Symbiosis - Abstract
International audience; The pea aphid genome includes 66 genes contributing to amino acid biosynthesis and 93 genes to amino acid degradation. In several respects, the pea aphid gene inventory complements that of its symbiotic bacterium, Buchnera aphidicola (Buchnera APS). Unlike other insects with completely sequenced genomes, the pea aphid lacks the capacity to synthesize arginine, which is produced by Buchnera APS. However, consistent with other insects, it has genes coding for individual reactions in essential amino acid biosynthesis, including threonine dehydratase and branched-chain amino acid aminotransferase, which are not coded in the Buchnera APS genome. Overall the genome data suggest that the biosynthesis of certain essential amino acids is shared between the pea aphid and Buchnera APS, providing the opportunity for precise aphid control over Buchnera metabolism.
- Published
- 2010
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