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8 results on '"MESH : Endemic Diseases"'

1. Acute lower respiratory infections on lung sequelae in Cambodia, a neglected disease in highly tuberculosis-endemic country

Author

Arnaud Tarantola, Patrich Lorn Try, Sophie Goyet, Sopheak Hem, Blandine Rammaert, Bertrand Guillard, Sokleaph Cheng, Charles Mayaud, Sirenda Vong, Laurence Borand, Sareth Rith, Philippe Buchy, Vantha Te, Institut Pasteur du Cambodge, Institut Pasteur du Cambodge-Réseau International des Instituts Pasteur ( RIIP ), Centre d'infectiologie Necker-Pasteur, Assistance publique - Hôpitaux de Paris (AP-HP)-CHU Necker - Enfants Malades [AP-HP], Donkeo Provincial Hospital, CHU Tenon [APHP], Rammaert B, Goyet S, Mayaud C, Buchy P, Borand L., Tarantola A, Hem S, Rith S, Cheng S, Te V, Try PL, Guillard B, Vong S, CHU Necker - Enfants Malades [AP-HP], Kampong Cham Provincial hospital, Kampong Cham Provincial hospital [Cambodia], Surveillance and Investigation of endemic situations in South-East Asia (SISEA) was funded by the French Agency for Development (Agence Française de Développement, AFD) and the US Department of Human and Health Services (US DHHS). Blandine Rammaert received a grant from the Fondation Pierre Ledoux Jeunesse Internationale and the Société de Pathologie Infectieuse de Langue Française., Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Réseau International des Instituts Pasteur (RIIP), CHU Tenon [AP-HP], and Sorbonne Université (SU)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)

Subjects
Male, MESH : Prospective Studies, MESH : Aged, Haemophilus influenzae, 0302 clinical medicine, [SDV.MHEP.MI]Life Sciences [q-bio]/Human health and pathology/Infectious diseases, Prospective Studies, MESH: Developing Countries, Respiratory Tract Infections, Aged, 80 and over, MESH: Middle Aged, MESH : Acute Disease, Neglected Diseases, MESH : Superinfection, MESH : Diagnosis, Differential, Countries, 3. Good health, Bronchiectasis, [ SDV.MHEP.MI ] Life Sciences [q-bio]/Human health and pathology/Infectious diseases, MESH: Young Adult, Acute Disease, MESH: Acute Disease, MESH : Hospitalization, MESH : Endemic Diseases, MESH : Community-Acquired Infections, Pulmonary and Respiratory Medicine, medicine.medical_specialty, Tuberculosis, MESH : Young Adult, [ SDV.MP.VIR ] Life Sciences [q-bio]/Microbiology and Parasitology/Virology, Article, 03 medical and health sciences, MESH: Anti-Bacterial Agents, MESH : Adolescent, Humans, MESH : Middle Aged, MESH : Developing Countries, Intensive care medicine, MESH : Aged, 80 and over, MESH: Age Distribution, Developing Countries, Tuberculosis, Pulmonary, Aged, MESH: Adolescent, MESH: Tuberculosis, Pulmonary, MESH: Humans, MESH : Cambodia, MESH : Humans, MESH: Adult, medicine.disease, 030228 respiratory system, Superinfection, Developing, Chest radiograph, MESH: Female, MESH : Tuberculosis, Pulmonary, Endemic Diseases, MESH : Age Distribution, MESH : Respiratory Tract Infections, MESH: Hospitalization, medicine.disease_cause, MESH: Aged, 80 and over, MESH : Female, 030212 general & internal medicine, Respiratory system, MESH : Anti-Bacterial Agents, MESH: Aged, medicine.diagnostic_test, Airway remodeling, MESH : Adult, Middle Aged, Anti-Bacterial Agents, Community-Acquired Infections, Hospitalization, medicine.anatomical_structure, MESH: Community-Acquired Infections, MESH: Endemic Diseases, Pseudomonas aeruginosa, Female, Abnormality, Cambodia, Adult, Adolescent, MESH : Male, Diagnosis, Differential, Young Adult, Age Distribution, MESH: Diagnosis, Differential, Internal medicine, Streptococcus pneumoniae, medicine, Lung, business.industry, MESH: Cambodia, MESH: Male, MESH: Prospective Studies, MESH: Superinfection, MESH: Respiratory Tract Infections, MESH: Neglected Diseases, business, MESH : Neglected Diseases
Abstract

International audience; BACKGROUND: Little is known about post-infectious pulmonary sequelae in countries like Cambodia where tuberculosis is hyper-endemic and childhood pulmonary infections are highly frequent. We describe the characteristics of hospitalized Cambodian patients presenting with community-acquired acute lower respiratory infections (ALRI) on post-infectious pulmonary sequelae (ALRIPS). METHODS: Between 2007 and 2010, inpatients ≥15 years with ALRI were prospectively recruited. Clinical, biological, radiological and microbiological data were collected. Chest radiographs were re-interpreted by experts to compare patients with ALRIPS, on previously healthy lungs (ALRIHL) and active pulmonary tuberculosis (TB). Patients without chest radiograph abnormality or with abnormality suggestive as other chronic respiratory diseases were excluded from this analysis. RESULTS: Among the 2351 inpatients with community-acquired ALRI, 1800 were eligible: 426 (18%) ALRIPS, 878 (37%) ALRIHL and 496 (21%) TB. ALRIPS patients had less frequent fever than other ALRI (p

Published
2013

2. Populations at risk for alveolar echinococcosis, France

Author

Piarroux, Martine, Piarroux, Renaud, Knapp, Jenny, Bardonnet, Karine, Dumortier, Jérôme, Watelet, Jérôme, Gerard, Alain, Beytout, Jean, Abergel, Armand, Bresson-Hadni, Solange, Gaudart, Jean, Surveillance Network, Francechino, Sciences Economiques et Sociales de la Santé & Traitement de l'Information Médicale (SESSTIM - U912 INSERM - Aix Marseille Univ - IRD), Institut de Recherche pour le Développement (IRD)-Aix Marseille Université (AMU)-Institut National de la Santé et de la Recherche Médicale (INSERM), Infections Parasitaires : Transmission, Physiopathologie et Thérapeutiques (IP-TPT), Institut de Recherche pour le Développement (IRD)-Aix Marseille Université (AMU)-Assistance Publique - Hôpitaux de Marseille (APHM)-Service de Santé des Armées, Laboratoire Chrono-environnement - CNRS - UBFC (UMR 6249) (LCE), Centre National de la Recherche Scientifique (CNRS)-Université de Franche-Comté (UFC), Université Bourgogne Franche-Comté [COMUE] (UBFC)-Université Bourgogne Franche-Comté [COMUE] (UBFC), Centre Hospitalier Régional Universitaire de Besançon (CHRU Besançon), service d'Hépato-gastro-entérologie, Hospices Civiles de Lyon-Hôpital Edouard Heriault, Service d'Hépato-gastro-entérologie [CHRU Nancy], Centre Hospitalier Régional Universitaire de Nancy (CHRU Nancy), Institut de Mécanique et d'Ingénierie de Bordeaux (I2M), Institut National de la Recherche Agronomique (INRA)-Université de Bordeaux (UB)-École Nationale Supérieure d'Arts et Métiers (ENSAM), Arts et Métiers Sciences et Technologies, HESAM Université (HESAM)-HESAM Université (HESAM)-Arts et Métiers Sciences et Technologies, HESAM Université (HESAM)-HESAM Université (HESAM)-Institut Polytechnique de Bordeaux-Centre National de la Recherche Scientifique (CNRS), Service des Maladies Infectieuses et Tropicales [CHU Clermont-Ferrand], CHU Gabriel Montpied [Clermont-Ferrand], CHU Clermont-Ferrand-CHU Clermont-Ferrand, Service d'hépatologie, CHU Etaing, Service de Santé des Armées-Assistance Publique - Hôpitaux de Marseille (APHM)-Aix Marseille Université (AMU)-Institut de Recherche pour le Développement (IRD), Laboratoire Chrono-environnement - UFC (UMR 6249) (LCE), Université Bourgogne Franche-Comté [COMUE] (UBFC)-Centre National de la Recherche Scientifique (CNRS)-Université de Franche-Comté (UFC), Hôpital Jean Minjoz, Centre Hospitalier Régional Universitaire [Besançon] (CHRU Besançon), Service des Maladies Infectieuses et Tropicales, Hôpital Gabriel Montpied, Clermont-Ferrand, France, Service des Maladies Infectieuses et Tropicales, Hopital Gabriel Montpied, Clermont-Ferrand, France, Laboratoire Chrono-environnement (UMR 6249) (LCE), HESAM Université - Communauté d'universités et d'établissements Hautes écoles Sorbonne Arts et métiers université (HESAM)-HESAM Université - Communauté d'universités et d'établissements Hautes écoles Sorbonne Arts et métiers université (HESAM)-Arts et Métiers Sciences et Technologies, HESAM Université - Communauté d'universités et d'établissements Hautes écoles Sorbonne Arts et métiers université (HESAM)-HESAM Université - Communauté d'universités et d'établissements Hautes écoles Sorbonne Arts et métiers université (HESAM)-Institut Polytechnique de Bordeaux-Centre National de la Recherche Scientifique (CNRS), Sciences Economiques et Sociales de la Santé & Traitement de l'Information Médicale ( SESSTIM ), Institut de Recherche pour le Développement ( IRD ) -Aix Marseille Université ( AMU ) -ORS PACA-Institut National de la Santé et de la Recherche Médicale ( INSERM ), Infections Parasitaires : Transmission, Physiopathologie et Thérapeutiques ( IP-TPT ), Institut de Recherche pour le Développement ( IRD ) -Aix Marseille Université ( AMU ) -Assistance Publique - Hôpitaux de Marseille ( APHM ) -Service de Santé des Armées-Université de Montpellier ( UM ), Laboratoire Chrono-environnement ( LCE ), Université Bourgogne Franche-Comté ( UBFC ) -Centre National de la Recherche Scientifique ( CNRS ) -Université de Franche-Comté ( UFC ), Centre Hospitalier Régional Universitaire [Besançon] ( CHRU Besançon ), Centre Hospitalier Régional Universitaire de Nancy ( CHRU Nancy ), Institut de Mécanique et d'Ingénierie de Bordeaux ( I2M ), Institut National de la Recherche Agronomique ( INRA ) -Université de Bordeaux ( UB ) -Institut Polytechnique de Bordeaux-Centre National de la Recherche Scientifique ( CNRS ), Institut de Recherche pour le Développement (IRD)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Aix Marseille Université (AMU), Sciences Economiques et Sociales de la Santé & Traitement de l'Information Médicale (SESSTIM), Aix Marseille Université (AMU) - ORS PACA - Institut National de la Santé et de la Recherche Médicale (INSERM), Laboratoire Chrono-environnement (LCE), Centre National de la Recherche Scientifique (CNRS) - Université de Franche-Comté (UFC), Hospices Civiles de Lyon - Hôpital Edouard Heriault, Service d'Hépatogastroentérologie, CHU de Nancy-Brabois, Université Sciences et Technologies - Bordeaux 1 - Arts et Métiers ParisTech - Institut Polytechnique de Bordeaux - Centre National de la Recherche Scientifique (CNRS), Service d'Hépato-Gastro-Entérologie, CHU de Clermont-Ferrand - Hôpital d'Estaing, and Aix Marseille Université (AMU)

Subjects
Male, Rural Population, [MATH.MATH-PR] Mathematics [math]/Probability [math.PR], Veterinary medicine, communicable disease prevention and control, MESH : Retrospective Studies, MESH : Anthelmintics, Alveolar echinococcosis, 0302 clinical medicine, [STAT.AP] Statistics [stat]/Applications [stat.AP], MESH: Rural Population, [SDV.SPEE] Life Sciences [q-bio]/Public Health and Epidemiology, Medicine, MESH: Animals, [SDV.MHEP.ME] Life Sciences [q-bio]/Human health and pathology/Emerging diseases, Anthelmintics, 0303 health sciences, MESH: Middle Aged, MESH: Echinococcosis, Hepatic, 3. Good health, MESH: Anthelmintics, agricultural workers diseases, alveolar echinococcosis, MESH : Endemic Diseases, Microbiology (medical), MESH : Albendazole, medicine.medical_specialty, Echinococcus multilocularis. epidemiology, Echinococcus multilocularis, Albendazole, lcsh:Infectious and parasitic diseases, 03 medical and health sciences, [SDV.EE.SANT] Life Sciences [q-bio]/Ecology, environment/Health, Humans, MESH : Middle Aged, Risk factor, MESH : Mebendazole, Retrospective Studies, MESH : Foxes, MESH: Echinococcus multilocularis, MESH: Humans, 030306 microbiology, MESH : Humans, lcsh:R, MESH: Adult, MESH: Retrospective Studies, Odds ratio, zoonoses, Relative risk, [SDE.ES] Environmental Sciences/Environmental and Society, MESH: Female, Demography, MESH: Liver, Endemic Diseases, MESH: Registries, Foxes, lcsh:Medicine, MESH : Echinococcus multilocularis, Risk Factors, MESH: Risk Factors, Epidemiology, MESH : Socioeconomic Factors, MESH : Female, Registries, rural health, [MATH.MATH-ST] Mathematics [math]/Statistics [math.ST], [STAT.ME] Statistics [stat]/Methodology [stat.ME], biology, Rural health, MESH : Adult, Middle Aged, MESH : Risk Factors, Mebendazole, Infectious Diseases, Liver, MESH: Endemic Diseases, [SDV.MHEP.MI] Life Sciences [q-bio]/Human health and pathology/Infectious diseases, Female, epidemiology, France, [SDV.MP.PAR] Life Sciences [q-bio]/Microbiology and Parasitology/Parasitology, Adult, [ SDV.MP.PAR ] Life Sciences [q-bio]/Microbiology and Parasitology/Parasitology, Echinococcosis, Hepatic, MESH: Socioeconomic Factors, MESH : Male, 030231 tropical medicine, [MATH.MATH-DS] Mathematics [math]/Dynamical Systems [math.DS], parasites, MESH: Mebendazole, Echinococcosis, MESH: Albendazole, Animals, lcsh:RC109-216, [SDV.MP.PAR]Life Sciences [q-bio]/Microbiology and Parasitology/Parasitology, MESH : France, MESH: Foxes, business.industry, Research, MESH : Liver, Retrospective cohort study, biology.organism_classification, MESH: Male, MESH : Rural Population, MESH: France, Socioeconomic Factors, MESH : Animals, business, MESH : Echinococcosis, Hepatic, MESH : Registries
Abstract

International audience; During 1982-2007, alveolar echinococcosis (AE) was diagnosed in 407 patients in France, a country previously known to register half of all European patients. To better define high-risk groups in France, we conducted a national registry-based study to identify areas where persons were at risk and spatial clusters of cases. We interviewed 180 AE patients about their way of life and compared responses to those of 517 controls. We found that almost all AE patients lived in 22 départements in eastern and central France (relative risk 78.63, 95% CI 52.84-117.02). Classification and regression tree analysis showed that the main risk factor was living in AE-endemic areas. There, most at-risk populations lived in rural settings (odds ratio [OR] 66.67, 95% CI 6.21-464.51 for farmers and OR 6.98, 95% CI 2.88-18.25 for other persons) or gardened in nonrural settings (OR 4.30, 95% CI 1.82-10.91). These findings can help sensitization campaigns focus on specific groups.

Published
2013

3. Detection of a high-endemic focus of Echinococcus multilocularis in red foxes in southern Denmark, January 2013

Author

M Staahl, Mariann Chriél, Mohammad Nafi Solaiman Al-Sabi, Jenny Knapp, Heidi L. Enemark, Laboratoire Chrono-environnement - CNRS - UBFC (UMR 6249) (LCE), Centre National de la Recherche Scientifique (CNRS)-Université de Franche-Comté (UFC), Université Bourgogne Franche-Comté [COMUE] (UBFC)-Université Bourgogne Franche-Comté [COMUE] (UBFC), Laboratoire Chrono-environnement ( LCE ), and Université Bourgogne Franche-Comté ( UBFC ) -Centre National de la Recherche Scientifique ( CNRS ) -Université de Franche-Comté ( UFC )

Subjects
Male, Veterinary medicine, Endemic Diseases, Epidemiology, Denmark, Foxes, MESH : Echinococcus multilocularis, MESH : Echinococcosis, MESH : Population Surveillance, MESH : Female, MESH: Animals, Intestinal Diseases, Parasitic, biology, MESH : Adult, Geography, Population Surveillance, MESH: Endemic Diseases, language, Female, MESH : Endemic Diseases, Adult, medicine.medical_specialty, MESH : Male, Echinococcus multilocularis, [ SDV.EE.SANT ] Life Sciences [q-bio]/Ecology, environment/Health, MESH: Population Surveillance, Danish, MESH: Echinococcosis, Echinococcosis, Virology, Environmental health, parasitic diseases, medicine, Animals, Humans, MESH : Foxes, MESH: Echinococcus multilocularis, [SDV.EE.SANT]Life Sciences [q-bio]/Ecology, environment/Health, MESH: Denmark, MESH: Foxes, MESH: Humans, MESH : Humans, Public Health, Environmental and Occupational Health, MESH: Adult, biology.organism_classification, language.human_language, MESH: Male, MESH: Intestinal Diseases, Parasitic, MESH : Denmark, MESH : Intestinal Diseases, Parasitic, MESH : Animals, MESH: Female
Abstract

International audience; The Danish surveillance programme for Echinococcus multilocularis was initiated in September 2011, and so far 679 wild carnivores have been examined. In April 2012, one infected fox was detected in Højer near the Danish-German border, and in January 2013 three additional foxes from the same area were found infected. Local prevalence in the area was 31% (four of 13 foxes) which is a new epidemiological situation calling for reevaluation of the national risk management.

Published
2012

4. [Alveolar echinococcosis: from an incurable rural disease to a controlled urban infection]

Author

Vuitton, Dominique Angèle, Bresson-Hadni, Solange, Giraudoux, Patrick, Bartholomot, Brigitte, Laplante, Jean-Jacques, Delabrousse, Eric, Blagosklonov, Oleg, Mantion, Georges, WHO Collaborating Center on Prevention and Treatment of Human Echinococcosis, Université de Franche-Comté ( UFC ), Carcinogénèse épithéliale : facteurs prédictifs et pronostiques - UFC ( CEF2P / CARCINO ), Centre Hospitalier Régional Universitaire [Besançon] ( CHRU Besançon ) -Université Bourgogne Franche-Comté ( UBFC ) -Université de Franche-Comté ( UFC ), Laboratoire Chrono-environnement ( LCE ), Université Bourgogne Franche-Comté ( UBFC ) -Université de Franche-Comté ( UFC ) -Centre National de la Recherche Scientifique ( CNRS ), WHO Collaborating Center on Prevention and Treatment of Human Echinococcosis, SERF Unit, Mutualité sociale agricole de Franche-Comté, Mutualité sociale agricole, Dept. of Nucl. Med., Jean Minjoz Univ. Hosp., Besancon, Centre Hospitalier Régional Universitaire [Besançon] ( CHRU Besançon ), Université de Franche-Comté (UFC), Université Bourgogne Franche-Comté [COMUE] (UBFC)-Université Bourgogne Franche-Comté [COMUE] (UBFC), Carcinogénèse épithéliale : facteurs prédictifs et pronostiques - UFC (EA 3181) (CEF2P / CARCINO), Centre Hospitalier Régional Universitaire de Besançon (CHRU Besançon)-Université de Franche-Comté (UFC), Laboratoire Chrono-environnement - CNRS - UBFC (UMR 6249) (LCE), Université Bourgogne Franche-Comté [COMUE] (UBFC)-Université Bourgogne Franche-Comté [COMUE] (UBFC)-Centre National de la Recherche Scientifique (CNRS), Service de Médecine nucléaire, biophysique, isotopes [CHRU Besançon], and Centre Hospitalier Régional Universitaire de Besançon (CHRU Besançon)

Subjects
MESH: Urban Health, Endemic Diseases, Aftercare, Rural Health, MESH : Echinococcus multilocularis, MESH : Early Diagnosis, MESH: Magnetic Resonance Imaging, MESH: Aftercare, MESH: Risk Factors, MESH: Early Diagnosis, Risk Factors, Zoonoses, MESH : Rural Health, MESH : Tomography, X-Ray Computed, Mass Screening, MESH: Animals, MESH: Anticestodal Agents, [SDV.MP.MYC]Life Sciences [q-bio]/Microbiology and Parasitology/Mycology, [ SDV.MP.MYC ] Life Sciences [q-bio]/Microbiology and Parasitology/Mycology, MESH: Echinococcosis, Hepatic, Magnetic Resonance Imaging, MESH : Risk Factors, MESH: Positron-Emission Tomography, MESH: China, Europe, MESH: Endemic Diseases, France, MESH: Tomography, X-Ray Computed, MESH: Zoonoses, MESH : Endemic Diseases, MESH : Albendazole, China, Echinococcosis, Hepatic, MESH : Europe, Albendazole, MESH : Zoonoses, MESH : Magnetic Resonance Imaging, MESH: Albendazole, Animals, Humans, MESH : China, MESH: Mass Screening, MESH : France, MESH: Echinococcus multilocularis, MESH : Mass Screening, MESH: Humans, MESH : Urban Health, MESH : Anticestodal Agents, MESH : Humans, Urban Health, Anticestodal Agents, MESH : Positron-Emission Tomography, MESH: Rural Health, MESH: France, Early Diagnosis, Positron-Emission Tomography, MESH : Aftercare, Echinococcus multilocularis, MESH: Europe, MESH : Animals, Tomography, X-Ray Computed, MESH : Echinococcosis, Hepatic
Abstract

International audience; Human alveolar echinococcosis is a parasitic zoonosis with intermediate (rodents and small lagomorphs) and final (carnivores) hosts. The latter can transmit the parasite to humans, by their feces, which are contaminated by the oncospheres of Echinococcus multilocularis, the larvae of which develop in the liver like a slow cancer. Political, socioeconomic, and ecological factors can affect the intermediate and final hosts and thus influence the long-term emergence and stability of endemic areas. The past 20 years have been marked by: Epidemiologic changes: discovery of an endemic area in China, the largest in the world; extension of the European endemic range to the east and north; extension of the French endemic range to the west and south; and the settlement of contaminated foxes in urban centers, which will modify the populations at risk over time. Progress in diagnosis: initial use of liver ultrasound to screen for asymptomatic disease; value of magnetic resonance imaging to confirm diagnosis and assess extension of disease before beginning treatment; mastery of immunological and genetic diagnosis; and the introduction of positron emission tomography combined with computed tomography to assess the functional activity of the lesions and monitor treatment. Consensus has defined the main directions of a multidisciplinary treatment approach: radical liver resection when possible; avoidance of palliative surgical procedures; use of interventional radiology or endoscopy to treat biliary and vascular complications, whenever possible; consideration of liver transplantation only when all other treatment possibilities have been exhausted; and treatment of all patients, without exception, by albendazole for at least two years after radical surgery and long term (at least several years) in other cases. In France, survival and quality of life have improved very substantially, due to earlier diagnosis, clinical classification of cases, and rigorous follow-up as part of the FrancEchino network. Better understanding of the immunological and immunogenetic mechanisms that underlie the course of disease may open up the possibility of immunomodulation that could replace or round out the current treatments. These are far from satisfactory, in view of the constraints of prolonged, most often life-long treatment by benzimidazoles and their side effects.

Published
2010

5. A correlative study of ultrasound with serology in an area in China co-endemic for human alveolar and cystic echinococcosis

Author

Yang, Y. R., Craig, P. S., Ito, A., Vuitton, D. A., Giraudoux, P., Sun, T., Williams, G. M., Huang, Z., Li, Zhenyu, Wang, Y., Teng, J., Li, Y., Huang, L., Wen, H., Jones, M. K., Mcmanus, D. P., Ningxia Medical College, Biomedical Sciences Research Institute, University of Salford, Department of Parasitology, Asahikawa Medical College, WHO Collaborating Center on Prevention and Treatment of Human Echinococcosis, SERF Unit, Université de Franche-Comté ( UFC ), Carcinogénèse épithéliale : facteurs prédictifs et pronostiques - UFC ( CEF2P / CARCINO ), Centre Hospitalier Régional Universitaire [Besançon] ( CHRU Besançon ) -Université Bourgogne Franche-Comté ( UBFC ) -Université de Franche-Comté ( UFC ), Laboratoire Chrono-environnement ( LCE ), Université Bourgogne Franche-Comté ( UBFC ) -Université de Franche-Comté ( UFC ) -Centre National de la Recherche Scientifique ( CNRS ), Molecular Parasitology Unit, University of Queensland [Brisbane]-The Queensland Institute of Medical Research-Australian Centre for International and Tropical Health and Nutrition ( ACITH ), Université de Franche-Comté (UFC), Université Bourgogne Franche-Comté [COMUE] (UBFC)-Université Bourgogne Franche-Comté [COMUE] (UBFC), Carcinogénèse épithéliale : facteurs prédictifs et pronostiques - UFC (EA 3181) (CEF2P / CARCINO), Université Bourgogne Franche-Comté [COMUE] (UBFC)-Université Bourgogne Franche-Comté [COMUE] (UBFC)-Centre Hospitalier Régional Universitaire de Besançon (CHRU Besançon), Laboratoire Chrono-environnement - CNRS - UBFC (UMR 6249) (LCE), Centre National de la Recherche Scientifique (CNRS)-Université de Franche-Comté (UFC), and Queensland Institute of Medical Research-University of Queensland [Brisbane]-Australian Centre for International and Tropical Health and Nutrition (ACITH)

Subjects
Male, MESH: Pulmonary Alveoli, Endemic Diseases, MESH : Aged, MESH: Comorbidity, Comorbidity, MESH : Child, Preschool, MESH : Echinococcosis, MESH: Cross Reactions, MESH : Child, MESH: Child, MESH : Population Surveillance, MESH : Female, Child, MESH: Echinococcosis, Pulmonary, MESH : Immunoblotting, Ultrasonography, MESH: Aged, MESH: Middle Aged, MESH: Immunoblotting, MESH : Cross Reactions, MESH: Echinococcosis, Hepatic, MESH: Enzyme-Linked Immunosorbent Assay, [ SDV.SPEE ] Life Sciences [q-bio]/Santé publique et épidémiologie, Middle Aged, MESH : Adult, MESH : Enzyme-Linked Immunosorbent Assay, MESH: China, Child, Preschool, Population Surveillance, MESH: Endemic Diseases, MESH : Comorbidity, Female, MESH : Endemic Diseases, Adult, MESH : Echinococcosis, Pulmonary, China, Echinococcosis, Hepatic, Echinococcosis, Pulmonary, MESH : Male, Immunoblotting, Enzyme-Linked Immunosorbent Assay, Cross Reactions, MESH: Population Surveillance, MESH: Echinococcosis, Echinococcosis, Humans, MESH : China, MESH : Middle Aged, Aged, MESH: Humans, MESH: Child, Preschool, MESH : Humans, MESH: Adult, MESH: Male, Pulmonary Alveoli, [SDV.SPEE]Life Sciences [q-bio]/Santé publique et épidémiologie, MESH : Pulmonary Alveoli, MESH : Echinococcosis, Hepatic, MESH: Female
Abstract

International audience; We correlated ultrasound (US) imaging classifications for human alveolar echinococcosis (AE) and cystic echinococcosis (CE) with serology (ELISA and immunoblotting (IB) incorporating native and recombinant/purified echinococcal antigens) in community surveys (2001-2003) and follow-up (2002 and 2003) of US-confirmed cases in Ningxia, China. One hundred and seventy-one cases (96 with AE, 75 with CE) were identified; of these, US classification and serological data were obtained for 142 and 112 cases, respectively. Seropositive-rates increased in CE patients with highly viable unilocular cyst lesions (Types CL, CE 1 or CE 2) to degenerating primary lesions (CE 3), but then decreased in subjects with inactive (CE 4) or dead (CE 5) cysts. In contrast, there was a constant increase in seropositivity from the early (P1, P2) to the advanced stages (P3, P4) with AE cases. For US-confirmed cases, follow-up by US combined with serology is invaluable for studying the clinical progression of echinococcosis and for detecting recurrent cysts or reinfection post-treatment.

Published
2007

6. Unique family clustering of human echinococcosis cases in a chinese community

Author

Xiaohui Feng, Yu Rong Yang, Dominique A. Vuitton, Hao Wen, Philip S. Craig, Xongzhou Liu, Patrick Giraudoux, Tao Sun, Magda K. Ellis, Akira Ito, Donald P. McManus, Belchis Boufana, Yunhai Wang, Brigitte Bartholomot, Zhengzhi Li, Ningxia Medical College, WHO Collaborating Center on Prevention and Treatment of Human Echinococcosis, SERF Unit, Université de Franche-Comté (UFC), Carcinogénèse épithéliale : facteurs prédictifs et pronostiques - UFC (EA 3181) (CEF2P / CARCINO), Université Bourgogne Franche-Comté [COMUE] (UBFC)-Centre Hospitalier Régional Universitaire [Besançon] (CHRU Besançon)-Université de Franche-Comté (UFC), Laboratoire Chrono-environnement - UFC (UMR 6249) (LCE), Université Bourgogne Franche-Comté [COMUE] (UBFC)-Centre National de la Recherche Scientifique (CNRS)-Université de Franche-Comté (UFC), Biomedical Sciences Research Institute, University of Salford, College of Information and Electrical Engineering [Beijing] (CIEE), China Agricultural University (CAU), Xinjiang Medical University, Chinese Government, Department of Parasitology, Asahikawa Medical College, Molecular Parasitology Unit, Queensland Institute of Medical Research-University of Queensland [Brisbane]-Australian Centre for International and Tropical Health and Nutrition (ACITH), Université Bourgogne Franche-Comté [COMUE] (UBFC)-Université Bourgogne Franche-Comté [COMUE] (UBFC), Université Bourgogne Franche-Comté [COMUE] (UBFC)-Université Bourgogne Franche-Comté [COMUE] (UBFC)-Centre Hospitalier Régional Universitaire de Besançon (CHRU Besançon), Laboratoire Chrono-environnement - CNRS - UBFC (UMR 6249) (LCE), Centre National de la Recherche Scientifique (CNRS)-Université de Franche-Comté (UFC), Université de Franche-Comté ( UFC ), Carcinogénèse épithéliale : facteurs prédictifs et pronostiques - UFC ( CEF2P / CARCINO ), Centre Hospitalier Régional Universitaire [Besançon] ( CHRU Besançon ) -Université Bourgogne Franche-Comté ( UBFC ) -Université de Franche-Comté ( UFC ), Laboratoire Chrono-environnement ( LCE ), Université Bourgogne Franche-Comté ( UBFC ) -Centre National de la Recherche Scientifique ( CNRS ) -Université de Franche-Comté ( UFC ), College of Information and Electrical Engineering [Beijing] ( CIEE ), China Agricultural University ( CAU ), University of Queensland [Brisbane]-The Queensland Institute of Medical Research-Australian Centre for International and Tropical Health and Nutrition ( ACITH ), ProdInra, Migration, Ningxia Medical University, Queensland Institute of Medical Research, Université Bourgogne Franche-Comté [COMUE] (UBFC), Unité sous contrat biologie environnementale, and Institut National de la Recherche Agronomique (INRA)-Université de Franche-Comté (UFC)

Subjects
Male, Rural Population, Veterinary medicine, Endemic Diseases, [SDV]Life Sciences [q-bio], MESH : Aged, Alveolar echinococcosis, MESH: Logistic Models, MESH : Echinococcus multilocularis, MESH: Echinococcus granulosus, 0302 clinical medicine, MESH : Child, MESH: Rural Population, Seroepidemiologic Studies, MESH: Child, Chinese community, MESH : Seroepidemiologic Studies, MESH : Female, MESH: Animals, Child, Ultrasonography, MESH: Aged, 0303 health sciences, MESH: Middle Aged, biology, MESH: Echinococcosis, Hepatic, Extended family, MESH: Enzyme-Linked Immunosorbent Assay, [ SDV.SPEE ] Life Sciences [q-bio]/Santé publique et épidémiologie, MESH : Adult, Middle Aged, Echinococcosis, MESH : Enzyme-Linked Immunosorbent Assay, MESH: China, 3. Good health, [SDV] Life Sciences [q-bio], Infectious Diseases, MESH: Endemic Diseases, Female, MESH : Endemic Diseases, Adult, medicine.medical_specialty, China, Echinococcosis, Hepatic, Adolescent, MESH : Male, 030231 tropical medicine, Helminthiasis, Antibodies, Helminth, Enzyme-Linked Immunosorbent Assay, Echinococcus multilocularis, 03 medical and health sciences, MESH: Antibodies, Helminth, Virology, MESH : Adolescent, medicine, MESH : China, Animals, Humans, MESH : Middle Aged, Family, MESH: Family, 030304 developmental biology, MESH : Antibodies, Helminth, Aged, MESH: Adolescent, MESH: Echinococcus multilocularis, MESH: Humans, MESH: Seroepidemiologic Studies, Echinococcus granulosus, Cystic echinococcosis, business.industry, MESH : Echinococcus granulosus, MESH : Humans, MESH: Adult, biology.organism_classification, medicine.disease, MESH: Male, MESH : Rural Population, Logistic Models, Tropical medicine, Parasitology, MESH : Family, [SDV.SPEE]Life Sciences [q-bio]/Santé publique et épidémiologie, MESH : Animals, business, MESH : Echinococcosis, Hepatic, MESH: Female, RESISTANCE, Demography, MESH : Logistic Models
Abstract

International audience; We have identified a significant focus and unusual clustering of human cases of cystic echinococcosis (CE) and alveolar echinococcosis (AE) in the village of Nanwan, Xiji County, Ningxia Hui Autonomous Region, in one of the most highly endemic areas for both diseases in China. The village, a Chinese Hui Islamic community, is composed of 167 members of four extended families. A total of 28 people died (12 of echinococcosis) since the village was first settled in the 1950s. Despite similar life patterns, the number of AE and CE cases occurring in each family was different. Overall, the prevalences of AE and CE were 9% (20 cases) and 5.9% (13 cases), with a combined prevalence of 14.9%. In contrast to CE, a comparison of the prevalence of AE indicated significant differences between the four family clusters. Although suggestive that host genotype might play a role in susceptibility to AE, this hypothesis requires further investigation.

Published
2006

7. [Relapse of Plasmodium malariae malaria 20 years after living in an endemic area]

Author

Siala, Emna, Khalfaoui, Moncef, Bouratbine, Aida, Hamdi, Samira, Hili, Kamel, Aoun, Karim, Laboratoire de Parasitologie Médicale, Biotechnologies et Biomolécules (LR11IPT06), Institut Pasteur de Tunis, Réseau International des Instituts Pasteur (RIIP)-Réseau International des Instituts Pasteur (RIIP), Infectious Diseases Department, Menzel Bourguiba Regional Hospital, Laboratoire de parasitologie-mycologie, parasitoses médicales, biotechnologie et biomolécules, Laboratoire de Parasitologie Médicale, Biotechnologies et Biomolécules ( LR11IPT06 ), Institut Pasteur de Tunis-Réseau International des Instituts Pasteur ( RIIP ), Institut des Maladies Métaboliques et Cardiovasculaires ( I2MC ), and Université Paul Sabatier - Toulouse 3 ( UPS ) -Hôpital de Rangueil-Institut National de la Santé et de la Recherche Médicale ( INSERM )

Subjects
Male, Tunisia, Endemic Diseases, MESH : Recurrence, MESH : Male, [SDV]Life Sciences [q-bio], MESH: Malaria, MESH : Malaria, Antimalarials, Plasmodium malariae, Recurrence, Residence Characteristics, MESH : Tunisia, parasitic diseases, MESH : Plasmodium malariae, Animals, Humans, MESH : Middle Aged, MESH: Animals, MESH: Residence Characteristics, MESH: Plasmodium malariae, MESH : Mefloquine, [SDV.MHEP.ME]Life Sciences [q-bio]/Human health and pathology/Emerging diseases, MESH: Humans, MESH: Middle Aged, [ SDV ] Life Sciences [q-bio], [ SDV.MHEP.ME ] Life Sciences [q-bio]/Human health and pathology/Emerging diseases, MESH : Humans, [ SDV.SPEE ] Life Sciences [q-bio]/Santé publique et épidémiologie, Middle Aged, MESH: Antimalarials, MESH: Male, MESH: Recurrence, Malaria, Mefloquine, MESH : Residence Characteristics, MESH: Endemic Diseases, MESH : Antimalarials, [SDV.SPEE]Life Sciences [q-bio]/Santé publique et épidémiologie, MESH : Animals, MESH: Tunisia, MESH : Endemic Diseases, MESH: Mefloquine
Abstract

International audience; INTRODUCTION:Malaria has been eradicated in Tunisia since 1979. Although it continues to be evoked in the case of fever after travel to an endemic zone, its diagnosis is however difficult during relapses, notably when they are delayed.OBSERVATION:A 50 year-old man having lived in Mauritania from 1978 to 1982 was hospitalized for interstitial pneumopathy and urarthritis. In spite of treatment with broad spectrum antibiotics, the fever accompanied by abundant sweating persisted. A thick blood drop and blood smear was requested and led to the diagnosis of Plasmodium malariae malaria.DISCUSSION:This observation recalls the possibility of parasitic upsurge of some plasmodial species. It should prompt physicians to be careful and evoke malaria in the case of fever in subjects having stayed, even several years before, in an endemic zone. This would permit early diagnosis and treatment.

Published
2005

8. Echinococcus multilocularis: secondary poisoning of fox population during a vole outbreak reduces environmental contamination in a high endemicity area

Author

Peter Deplazes, Pierre Delattre, Francis Raoul, Y Décoté, M Ordinaire, Dominique Michelat, Patrick Giraudoux, M Aubert, Laboratoire Chrono-environnement - UFC (UMR 6249) (LCE), Université Bourgogne Franche-Comté [COMUE] (UBFC)-Centre National de la Recherche Scientifique (CNRS)-Université de Franche-Comté (UFC), Laboratoire d'études et de recherches sur la rage et la pathologie des animaux sauvages, AFSSA, Centre de Biologie pour la Gestion des Populations (UMR CBGP), Centre de Coopération Internationale en Recherche Agronomique pour le Développement (Cirad)-Institut National de la Recherche Agronomique (INRA)-Centre international d'études supérieures en sciences agronomiques (Montpellier SupAgro)-Université de Montpellier (UM)-Institut de Recherche pour le Développement (IRD [France-Sud])-Institut national d’études supérieures agronomiques de Montpellier (Montpellier SupAgro), Institute of Parasitology, Laboratoire Chrono-environnement - CNRS - UBFC (UMR 6249) (LCE), Centre National de la Recherche Scientifique (CNRS)-Université de Franche-Comté (UFC), Université Bourgogne Franche-Comté [COMUE] (UBFC)-Université Bourgogne Franche-Comté [COMUE] (UBFC), Agence Française de Sécurité Sanitaire des Aliments (AFSSA), Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro)-Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro), Laboratoire Chrono-environnement ( LCE ), Université Bourgogne Franche-Comté ( UBFC ) -Centre National de la Recherche Scientifique ( CNRS ) -Université de Franche-Comté ( UFC ), Centre de Biologie pour la Gestion des Populations ( CBGP ), and Centre de Coopération Internationale en Recherche Agronomique pour le Développement ( CIRAD ) -Centre international d'études supérieures en sciences agronomiques ( Montpellier SupAgro ) -Institut national de la recherche agronomique [Montpellier] ( INRA Montpellier ) -Université de Montpellier ( UM ) -Institut de Recherche pour le Développement ( IRD [France-Sud] ) -Institut national d’études supérieures agronomiques de Montpellier ( Montpellier SupAgro )

Subjects
Veterinary medicine, Endemic Diseases, Bromadiolone, Foxes, MESH: Echinococcus, MESH: 4-Hydroxycoumarins, MESH : Echinococcosis, Population density, MESH : Pest Control, 030308 mycology & parasitology, chemistry.chemical_compound, 0302 clinical medicine, MESH : Echinococcus, MESH: Animals, [SDV.EE]Life Sciences [q-bio]/Ecology, environment, 0303 health sciences, education.field_of_study, biology, Ecology, Arvicolinae, Environmental exposure, MESH : 4-Hydroxycoumarins, Population decline, Infectious Diseases, MESH: Endemic Diseases, MESH: Pest Control, France, MESH : Endemic Diseases, MESH: Population Density, 030231 tropical medicine, Population, MESH: Environmental Exposure, MESH: Rodenticides, Echinococcus multilocularis, [ SDV.EE ] Life Sciences [q-bio]/Ecology, environment, 03 medical and health sciences, MESH: Echinococcosis, Echinococcosis, parasitic diseases, Animals, MESH : Population Density, MESH : France, Microtus, education, MESH : Foxes, Population Density, MESH: Foxes, Outbreak, Rodenticides, MESH : Rodenticides, 4-Hydroxycoumarins, Environmental Exposure, MESH: Arvicolinae, biology.organism_classification, Echinococcus, MESH : Arvicolinae, MESH: France, chemistry, Parasitology, MESH : Animals, Pest Control, MESH : Environmental Exposure
Abstract

International audience; This paper describes the role of fox population level on Echinococcus multilocularis infection in foxes in a highly endemic area in eastern France. Fox population level was monitored by spotlight survey at Le Souillot from 1989 to 2000, and from 1992 to 2000 at Chemin, a control site located in a low endemic area. The infection level of the fox population was estimated at Le Souillot from winter 1995 to winter 1999 using a coproantigen ELISA performed on faeces collected in the field. Population biomass of intermediate hosts (Microtus arvalis and Arvicola terrestris) was monitored using index methods from 1995 to 1999. At Le Souillot, a significant decline in the fox population level was recorded after spring 1997 (P

Published
2003

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