Search

Your search keyword '"MICHALEWSKA Z"' showing total 122 results
Start Over Author "MICHALEWSKA Z"
122 results on '"MICHALEWSKA Z"'

3. Vision-Related Quality of Life in Patients with Diabetic Macular Edema Treated with Intravitreal Aflibercept: The AQUA Study

Author

Garweg, Jg, Stefanickova, J, Hoyng, C, Schmelter, T, Niesen, T, Sowade, O, Sivaprasad, S, Adan, A, Alexik, M, Ali, F, Amaro, M, Balciuniene, V, Bandello, Fm, Arias Barquet, L, Beck, A, Bell, K, Boscia, F, Bures, A, Carneiro, A, Chow, Dr, Cimbalas, A, Dahlke, C, Deepali, V, Dickinson, Jd, Dollin, M, Eandi, C, Emmerich, K, Feltgen, N, Pereira Figueira, J, Findl, O, Gajdosova, M, Gale, Rp, John Galic, I, Garweg, J, Gasser-Steiner, V, Giunta, M, Gonder, Jr, Grzybowski, A, Hamouz, J, Hattenbach, L, Holz, Fg, Jesia, H, Kaluzny, J, Kerenyi, A, Kertes, Pj, Koch, F, Kodjikan, L, Lederer, De, Liehneova, I, Lorenz, K, Lotery, Aj, Mckibbin, M, Menon, Gv, Michalewska, Z, Midena, E, Nicolo, M, Papp, A, Pavlovicova, G, Peiretti, E, Vaz-Pereira, S, Perri, P, Petropoulos, I, Queguiner, F, Raczynska, K, Sararols-Ramsay, L, Rekas, M, Ricci, F, Romanowska-Dixon, B, Sachs, Hg, Mohand-Said, S, Sandner, D, Schmidt-Erfurth, U, Sekundo, W, Seres, A, Souied, E, Castro de Sousa, J, Stankiewicz, A, Struharova, K, Studnicka, J, Cervera Taulet, E, Taylor, S, Teper, S, Vajas, A, Cava Valenciano, C, Varsanyi, B, Viola, F, Virgili, G, Wagenfeld, L, Walters, G, Wiedemann, P, Zarnowski, T, Garweg, J. G., Stefanickova, J., Hoyng, C., Schmelter, T., Niesen, T., Sowade, O., Sivaprasad, S., Adan, A., Alexik, M., Ali, F., Amaro, M., Balciuniene, V. -J., Bandello, F. M., Arias Barquet, L., Beck, A., Bell, K., Boscia, F., Bures, A., Carneiro, A., Chow, D. R., Cimbalas, A., Dahlke, C., Deepali, V., Dickinson, J. D., Dollin, M., Eandi, C., Emmerich, K. -H., Feltgen, N., Pereira Figueira, J., Findl, O., Gajdosova, M., Gale, R. P., John Galic, I., Garweg, J., Gasser-Steiner, V., Giunta, M., Gonder, J. R., Grzybowski, A., Hamouz, J., Hattenbach, L. -O., Holz, F. G., Jesia, H., Kaluzny, J., Kerenyi, A., Kertes, P. J., Koch, F., Kodjikan, L., Lederer, D. E., Liehneova, I., Lorenz, K., Lotery, A. J., Mckibbin, M., Menon, G. V., Michalewska, Z., Midena, E., Nicolo, M., Papp, A., Pavlovicova, G., Peiretti, E., Vaz-Pereira, S., Perri, P., Petropoulos, I., Queguiner, F., Raczynska, K., Sararols-Ramsay, L., Rekas, M., Ricci, F., Romanowska-Dixon, B., Sachs, H. G., Mohand-Said, S., Sandner, D., Schmidt-Erfurth, U., Sekundo, W., Seres, A., Souied, E., Castro de Sousa, J., Stankiewicz, A., Struharova, K., Studnicka, J., Cervera Taulet, E., Taylor, S., Teper, S., Vajas, A., Cava Valenciano, C., Varsanyi, B., Viola, F., Virgili, G., Wagenfeld, L., Walters, G., Wiedemann, P., and Zarnowski, T.

Subjects
Male, Vascular Endothelial Growth Factor A, Diabetic Retinopathy, Recombinant Fusion Proteins, Visual Acuity, Angiogenesis Inhibitors, Middle Aged, Macular Edema, Diabetes Mellitus, Type 1, Receptors, Vascular Endothelial Growth Factor, Diabetes Mellitus, Type 2, Settore MED/30, Sickness Impact Profile, Surveys and Questionnaires, Intravitreal Injections, Quality of Life, Humans, Female, Single-Blind Method, Tomography, Optical Coherence, Vision, Ocular, Aged
Abstract

Purpose: To examine vision-related quality of life in patients with diabetic macular edema (DME) treated with intravitreal aflibercept (EYLEA, Regeneron Pharmaceuticals, Inc, Tarrytown, NY). Design: AQUA was a multicenter, open-label, single-arm, phase 4 study. Participants: Adults 18 years of age or older with type 1 or 2 diabetes mellitus and DME. Methods: Patients received intravitreal aflibercept 2 mg every 8 weeks for 52 weeks, after 5 initial doses every 4 weeks. Main Outcome Measures: The primary outcome was the change in 25-item National Eye Institute Visual Function Questionnaire (NEI VFQ-25) total score from baseline to week 52. Secondary outcomes included the change in NEI VFQ-25 near and distant activities subscale scores, best-corrected visual acuity (BCVA; Early Treatment Diabetic Retinopathy Study [ETDRS] letters), and central retinal thickness (CRT) from baseline to week 52. Change in NEI VFQ-25 score at week 52 for better-seeing eyes (BSEs) and worse-seeing eyes (WSEs) also was evaluated. Results: A total of 553 patients comprised the full analysis set, and 560 patients comprised the safety analysis set. At baseline, the mean NEI VFQ-25 total score was 70.12, mean BCVA was 61.5 ETDRS letters, and mean CRT was 464.81 μm. A mean of 8.8 injections were administered over 52 weeks. At week 52, the mean improvement from baseline in the NEI VFQ-25 total score was +6.11 (standard deviation [SD], 11.46); the corresponding improvements in near and distant activities were +11.37 (SD, 18.01) and +7.33 (SD, 17.32), respectively. Similarly, improvements in patients whose BSE and WSE were treated were 7.74 (SD, 13.59) and 5.48 (SD, 9.70), respectively. At week 52, mean change in BCVA was +10.0 ETDRS letters (SD, 8.0 ETDRS letters), and mean change in CRT was –175.38 μm (SD, 132.62 μm). Overall, 53.6% of patients reported treatment-emergent adverse events (TEAEs), of whom 26.8% experienced an ocular TEAE in the study eye. The most common serious ocular TEAE was endophthalmitis (0.5% [n = 3]). Five deaths (0.9%) were reported, but were not considered treatment related. Conclusions: Intravitreal aflibercept was associated with clinically meaningful improvements in NEI VFQ-25 total score over 52 weeks in patients with DME; these were even more pronounced for near than for distant activities. Adverse events were consistent with the known safety profile of intravitreal aflibercept.

Published
2019

4. An international collaborative evaluation of central serous chorioretinopathy: different therapeutic approaches and review of literature. The European Vitreoretinal Society central serous chorioretinopathy study

Author

Romano, M. R., Parolini, B., Allegrini, D., Mickalewska, Z., Adelman, R., Bonovas, S., Bopp, S., Citirik, M., Tekin, K., Fiser, I., Boon, C. J. F., Van, D., Donvito, G., Gungel, H., Ozdogan Erkul, S., Unsal, E., Osmanbasoglu, O., Dincer, N., Ercalik, N. Y., Yenerel, N. M., Amar, J. -P., Ennemoser, A., Besozzi, G., Sallam, A. A. B., Ellabban, A. A., Chang, W., Eandi, C. M., Demir, M., Lee, J., Pak, K., Arrevola, L., Sloka, A., Morawski, K., Kulig - Stochmal, A., Romanowska - Dixon, B., Striebe, N. -A., Feltgen, N., Hoerauf, H., Inan, U. U., Tanev, I., Dyrda, A., Schuler, A., Lucke, K., Brix, A., Pape, S., Kusserow-Napp, C., Loo, P. A., Kanra, A. Y., Ardagil Akcakaya, A., Ari Yaylali, S., Bae, S. H., Kim, H. K., Kim, S. J., Han, J. R., Nam, W. H., Odrobina, D., Lavaque, E., Bertelli, E., Coser, S., Ziemssen, F., Forlini, M., Benatti, C., Cavallini, G. M., Stefanickova, J., Berrod, J. -P., Saksonov, S., Lytvinchuk, L., Moussa, M., Stefaniotou, M., Christodoulou, E., Zayed, M. A., Oz, O., Tassinari, P., Koch, P., Declercq, C., Johnston, R., Rusnak, S., Penas, S., Ozdek, S., Ucgul, Y., Cisiecki, S., Dziegielewski, K., Klimczak, D., Michalewska, Z., Michalewski, J., Nawrocka, Z., Nawrocki, J., Ornafel, K., Pikulski, Z., Maciej, M., Acar, N., Elshafei, M. M., Hamon, F., Soyeur, R., Badat, I., Brousseau, B., Hermouet, E., Peiretti, E., Lee, J. -H., Ferreira, N., Yoon, H. -S., Alkhars, W. I., Dudani, A., Minu, R., Telang, O., Morepatil, V. G., Furtado, M. J., Y. -J., Jo, Piccolino, F. C., Finzi, A., Ophthalmology, and Amsterdam Neuroscience - Complex Trait Genetics

Subjects
Pars plana, medicine.medical_specialty, Visual acuity, medicine.medical_treatment, Vitrectomy, 03 medical and health sciences, 0302 clinical medicine, PDT, Ophthalmology, medicine, central serous chorioretinopathy, First episode, Aspirin, Univariate analysis, medicine.diagnostic_test, business.industry, General Medicine, Fluorescein angiography, eye diseases, laser, Serous fluid, medicine.anatomical_structure, 030221 ophthalmology & optometry, medicine.symptom, business, 030217 neurology & neurosurgery, medicine.drug
Abstract

Purpose: To study and compare the efficacy of different therapeutic options for the treatment of central serous chorioretinopathy (CSCR). Methods: This is a nonrandomized, international multicentre study on 1719 patients (1861 eyes) diagnosed with CSCR, from 63 centres (24 countries). Reported data included different methods of treatment and both results of diagnostic examinations [fluorescein angiography and/or optical coherent tomography (OCT)] and best-corrected visual acuity (BCVA) before and after therapy. The duration of observation had a mean of 11 months but was extended in a minority of cases up to 7 years. The aim of this study is to evaluate the efficacy of the different therapeutic options of CSCR in terms of both visual (BCVA) and anatomic (OCT) improvement. Results: One thousand seven hundred nineteen patients (1861 eyes) diagnosed with CSCR were included. Treatments performed were nonsteroidal anti-inflammatory eye drops, laser photocoagulation, micropulse diode laser photocoagulation, photodynamic therapy (PDT; Standard PDT, Reduced-dose PDT, Reduced-fluence PDT), intravitreal (IVT) antivascular endothelial growth factor injection (VEGF), observation and other treatments. The list of the OTHERS included both combinations of the main proposed treatments or a variety of other treatments such as eplerenone, spironolactone, acetazolamide, beta-blockers, anti-anxiety drugs, aspirin, folic acid, methotrexate, statins, vitis vinifera extract medication and pars plana vitrectomy. The majority of the patients were men with a prevalence of 77%. The odds ratio (OR) showed a partial or complete resolution of fluid on OCT with any treatment as compared with observation. In univariate analysis, the anatomical result (improvement in subretinal fluid using OCT at 1 month) was favoured by age 500 μm (p = 0.03). The OR for obtaining partial or complete resolution showed that anti-VEGF and eyedrops were not statistically significant; whereas PDT (8.5), thermal laser (11.3) and micropulse laser (8.9) lead to better anatomical results with less variability. In univariate analysis, the functional result at 1 month was favoured by first episode (p = 0.04), height of subretinal fluid >500 μm (p

Published
2019
Full Text
View/download PDF

5. International Practice Patterns for the Management of Acute Postsurgical and Postintravitreal Injection Endophthalmitis: European Vitreo-Retinal Society Endophthalmitis Study Report 1

Author

Soliman, M. K., Gini, G., Kuhn, F., Iros, M., Parolini, B., Ozdek, S., Michalewska, Z., Bopp, S., Adelman, R. A., Sallam, A. B., Kardaszewska, A., M'Bongo Zindamoyen, A. N., Banker, A., Serhiienko, A., Loo, A., Meireles, A., Aydin, B., Luebke, B., Ozmen, C., Odrobina, D., Bertelli, E., Unsal, E., Kenneth, F., Becquet, F., Hamon, F., Pellegrini, G., Tosi, G. M., Donvito, G., Khaqan, H., Badat, I., Fiser, I., Michalewski, J., Francois Le Rouic, J., Nawrocki, J., Zarallo-Gallardo, J., Lee, J. H., Boninska, K., Nowomiejska, K., Dziegielewski, K., Arrevola, L., Lytvynchuk, L., Elshafei, M., Pietras-Trzpiel, M., Detjen, M., Iglicki, M., Badino, M., Angelina, M., Gavura, M., Hasanreisoglu, M., Karadas, M., Atienza, N., Acar, N., Okonkwo, O., Miesbauer, P., Malgorzata, P. -T., Velez-Montoya, R., Robert, R., Frisina, R., Soyeur, R., Rejdak, R., Giannini, R., Mittal, S., Saidkasimova, S., Abdulsalam, S., Cisiecki, S., Rusnak, S., Teoh, S., Teixeira, S., Altan, T., Schrader, W., Kapran, Z., Aktas, Z., and Szijarto, Z.

Subjects
Male, Endophthalmitis, Incidence, Eye Infections, Bacterial, Disease Management, Angiogenesis Inhibitors, Cataract Extraction, Aged, Anti-Bacterial Agents, Antibiotic Prophylaxis, Europe, Eye Infections, Bacterial, Female, Follow-Up Studies, Humans, Intravitreal Injections, Middle Aged, Ophthalmology, Practice Guidelines as Topic, Retrospective Studies, Societies, Medical, Surgical Wound Infection, Vitrectomy, Medical, Societies
Published
2019

6. 'Same day' vitrectomy to treat endophthalmitis in the course of anti-VEGF treatment for AMD can save the eye and restore visual acuity

Author

Michalewska, Z, Boninska, K, and Nawrocki, J

Subjects
ddc: 610, genetic structures, sense organs, 610 Medical sciences, Medicine, eye diseases
Abstract

Goal: To present effects of long-term anti-VEGF (Vascular Endothelial Growth Factor) treatment in eyes after vitrectomy for endophthalmitis in neovascular age related macular degeneration. Methods: Core vitrectomy, with intravitreal vancomycin was performed. Spectral domain optical coherence tomography[for full text, please go to the a.m. URL], 31. Internationaler Kongress der Deutschen Ophthalmochirurgen

Published
2018
Full Text
View/download PDF

11. Strategy for the management of uncomplicated retinal detachments: the European vitreo-retinal society retinal detachment study report 1

Author

BENMERZOUGA N, METTI F, RAZZARI A, MIESBAUER P, SCHÖNHERR U, ZEYNALOVA Z, BASHIR SJ, JACOB J, KOCH P, LADHA R, SMETS E, STALMANS P, DARE A, DEVENYI R, LAM WC, SHAHEEDA M, POTAMITIS T, CHRISTENSEN SR, RAYES E, MORTADA H, SHOUMAN A, HOLM M, ALBINET P, AMAR JP, BECQUET F, BERROD JP, BOULZE M, BOSCHER C, COURJARET JC, DENION E, FOURMAUX, E, GUIGOU S, HAMON F, LAFONTAINE PO, LE ROUIC JF, LEYNAUD JL, NOCHEZ Y, PERONE JM, RYSANEK B, SOYEUR R, BOPP S, BRIX A, HÖHN F, KUSSEROW C, LUCKE K, MOHR A, SCHÜLER A, WEINBERGER A, GOTZARIDIS S, KARATZENIS D, STEFANIOTOU M, K. TSILIMBARIS MK, TSOURIS D, TSANG CW, GABOR R, SZIJARTO Z, BABU N, BANKER AS, BAPAYE M, KELKAR A, ENTEZARI, M, FATEH MOGHADAM HF, RAMEZANI A, SAFARPOUR LIMA B, OMER K, BOSCIA F, CHIARA FRENO M, CIAN R, DONVITO G, FACINO M, LESNONI G, LIUZZI, F, METE M, MININNI F, MOCHI B, PRIMAVERA V, PERTILE G, TURCO I, VASTARELLA P, FONG K, LEE M, VP LOO A, ARAGON HARRISON O, FLORES AGUILAR M, LOPEZ MONTERO LM, LOPEZCARASA HERNANDEZ G, VELASCO I, BOEYDEN V, BOSSCHA M, DE VRIES KNOPPERT W, LINDSTEDT, E. RENARDEL DE LAVALETTE VW, VAN DEN BIESEN PR, ALHASSAN M, BAERLAND TP, BOBER AM, FORSAA V, FOSSEN K, VARHAUG P, ATIENZA J.r. NF, CISIECKI S, FRYCZKOWSKI P, KOWAL LANGE A, MICHALEWSKA Z, MICHALEWSKI J, NAWROCKI J, NOWOSIELSKA A, ODROBINA D, PIETRAS TRZPIEL M, ZAKRZEWSKA A, MEIRELES A, TEIXEIRA S, ELSHAFEI M, DANIELESCU C, TALU S, ALTYNBAEV U, GORIN A, SEREJINE I, EL DEEB M, DAVIDOVIC S, IGNJATOVIC Z, STEFANICKOVA J, VENTER L, CHANG W, JO YL, KIM JY, LEE J, LIM ST, SAGONG M, ASCASO FJ, CASTRO J, CORDOVES L. DESCO ESTEBAN C, MORENO MANRESA J, VILAPLANA D, JANIEC S, TOMIC Z, BEN YAHIA S, ACAR N, GÜNGEL H, KAPRAN Z, OSMANBASOGLU O, OZDEK S, TOPBAS S, TOTAN Y, ÜNVER YB, CHICHUR D, DOBROVOLSKEY O, KOZLOVSKA I, LYTVYNCHUK L, PHYLYPCHUK O, POSTOLOVSKA A, SERGIIENKO A, SHEVCHYK V, WINDER S, CULOTTA J, KIM S, KING J, KURUP SK, LIN SJ, PACURARIU R, ROTH D, SINCLAIR S, WEBER P, DOAN H, TUNG T., ROMANO, MARIO, Benmerzouga, N, Metti, F, Razzari, A, Miesbauer, P, Schönherr, U, Zeynalova, Z, Bashir, Sj, Jacob, J, Koch, P, Ladha, R, Smets, E, Stalmans, P, Dare, A, Devenyi, R, Lam, Wc, Shaheeda, M, Potamitis, T, Christensen, Sr, Rayes, E, Mortada, H, Shouman, A, Holm, M, Albinet, P, Amar, Jp, Becquet, F, Berrod, Jp, Boulze, M, Boscher, C, Courjaret, Jc, Denion, E, Fourmaux, E, Guigou, S, Hamon, F, Lafontaine, Po, LE ROUIC, Jf, Leynaud, Jl, Nochez, Y, Perone, Jm, Rysanek, B, Soyeur, R, Bopp, S, Brix, A, Höhn, F, Kusserow, C, Lucke, K, Mohr, A, Schüler, A, Weinberger, A, Gotzaridis, S, Karatzenis, D, Stefaniotou, M, K., TSILIMBARIS MK, Tsouris, D, Tsang, Cw, Gabor, R, Szijarto, Z, Babu, N, Banker, A, Bapaye, M, Kelkar, A, Entezari, M, FATEH MOGHADAM, Hf, Ramezani, A, SAFARPOUR LIMA, B, Omer, K, Boscia, F, CHIARA FRENO, M, Cian, R, Donvito, G, Facino, M, Lesnoni, G, Liuzzi, F, Mete, M, Mininni, F, Mochi, B, Primavera, V, Romano, Mario, Pertile, G, Turco, I, Vastarella, P, Fong, K, Lee, M, VP LOO, A, ARAGON HARRISON, O, FLORES AGUILAR, M, LOPEZ MONTERO, Lm, LOPEZCARASA HERNANDEZ, G, Velasco, I, Boeyden, V, Bosscha, M, DE VRIES KNOPPERT, W, Lindstedt, E., RENARDEL DE LAVALETTE VW, VAN DEN BIESEN, Pr, Alhassan, M, Baerland, Tp, Bober, Am, Forsaa, V, Fossen, K, Varhaug, P, ATIENZA J. r., Nf, Cisiecki, S, Fryczkowski, P, KOWAL LANGE, A, Michalewska, Z, Michalewski, J, Nawrocki, J, Nowosielska, A, Odrobina, D, PIETRAS TRZPIEL, M, Zakrzewska, A, Meireles, A, Teixeira, S, Elshafei, M, Danielescu, C, Talu, S, Altynbaev, U, Gorin, A, Serejine, I, EL DEEB, M, Davidovic, S, Ignjatovic, Z, Stefanickova, J, Venter, L, Chang, W, Jo, Yl, Kim, Jy, Lee, J, Lim, St, Sagong, M, Ascaso, Fj, Castro, J, CORDOVES L., DESCO ESTEBAN C, MORENO MANRESA, J, Vilaplana, D, Janiec, S, Tomic, Z, BEN YAHIA, S, Acar, N, Güngel, H, Kapran, Z, Osmanbasoglu, O, Ozdek, S, Topbas, S, Totan, Y, Ünver, Yb, Chichur, D, Dobrovolskey, O, Kozlovska, I, Lytvynchuk, L, Phylypchuk, O, Postolovska, A, Sergiienko, A, Shevchyk, V, Winder, S, Culotta, J, Kim, S, King, J, Kurup, Sk, Lin, Sj, Pacurariu, R, Roth, D, Sinclair, S, Weber, P, Doan, H, and Tung, T.

Abstract

OBJECTIVE: To study success and failure in the treatment of uncomplicated rhegmatogenous retinal detachments (RRDs). DESIGN: Nonrandomized, multicenter retrospective study. PARTICIPANTS: One hundred seventy-six surgeons from 48 countries spanning 5 continents provided information on the primary procedures for 7678 cases of RRDs including 4179 patients with uncomplicated RRDs. METHODS: Reported data included specific clinical findings, the method of repair, and the outcome after intervention. MAIN OUTCOME MEASURES: Final failure of retinal detachment repair (level 1 failure rate), remaining silicone oil at the study's conclusion (level 2 failure rate), and need for additional procedures to repair the detachment (level 3 failure rate). RESULTS: Four thousand one hundred seventy-nine uncomplicated cases of RRD were included. Combining phakic, pseudophakic, and aphakic groups, those treated with scleral buckle alone (n = 1341) had a significantly lower final failure rate than those treated with vitrectomy, with or without a supplemental buckle (n = 2723; P = 0.04). In phakic patients, final failure rate was lower in the scleral buckle group compared with those who had vitrectomy, with or without a supplemental buckle (P = 0.028). In pseudophakic patients, the failure rate of the initial procedure was lower in the vitrectomy group compared with the scleral buckle group (P = 3×10(-8)). There was no statistically significant difference in failure rate between segmental (n = 721) and encircling (n = 351) buckles (P = 0.5). Those who underwent vitrectomy with a supplemental scleral buckle (n = 488) had an increased failure rate compared with those who underwent vitrectomy alone (n = 2235; P = 0.048). Pneumatic retinopexy was found to be comparable with scleral buckle when a retinal hole was present (P = 0.65), but not in cases with a flap tear (P = 0.034). CONCLUSIONS: In the treatment of uncomplicated phakic retinal detachments, repair using scleral buckle may be a good option. There was no significant difference between segmental versus 360-degree buckle. For pseudophakic uncomplicated retinal detachments, the surgeon should balance the risks and benefits of vitrectomy versus scleral buckle and keep in mind that the single-surgery reattachment rate may be higher with vitrectomy. However, if a vitrectomy is to be performed, these data suggest that a supplemental buckle is not helpful.

Published
2013

12. Strategy for the management of complex retinal detachments: the European vitreo-retinal society retinal detachment study report 2

Author

BENMERZOUGA N, METTI F, RAZZARI A, MIESBAUER P, SCHÖNHERR U, ZEYNALOVA Z, BASHIR SJ, JACOB J, KOCH P, LADHA R, SMETS E, STALMANS P, DARE A, DEVENYI R, LAM WC, SHAHEEDA M, POTAMITIS T, CHRISTENSEN SR, RAYES E, MORTADA H, SHOUMAN A, HOLM M, ALBINET P, AMAR JP, BECQUET F, BERROD JP, BOULZE M, BOSCHER C, COURJARET JC, DENION E, FOURMAUX, E, GUIGOU S, HAMON F, LAFONTAINE PO, LE ROUIC JF, LEYNAUD JL, NOCHEZ Y, PERONE JM, RYSANEK B, SOYEUR R, BOPP S, BRIX A, HÖHN F, KUSSEROW C, LUCKE K, MOHR A, SCHÜLER A, WEINBERGER A, GOTZARIDIS S, KARATZENIS D, STEFANIOTOU M, K. TSILIMBARIS MK, TSOURIS D, TSANG CW, GABOR R, SZIJARTO Z, BABU N, BANKER AS, BAPAYE M, KELKAR A, ENTEZARI, M, FATEH MOGHADAM HF, RAMEZANI A, SAFARPOUR LIMA B, OMER K, BOSCIA F, CHIARA FRENO M, CIAN R, DONVITO G, FACINO M, LESNONI G, LIUZZI, F, METE M, MININNI F, MOCHI B, PRIMAVERA V, PERTILE G, TURCO I, VASTARELLA P, FONG K, LEE M, VP LOO A, ARAGON HARRISON O, FLORES AGUILAR M, LOPEZ MONTERO LM, LOPEZCARASA HERNANDEZ G, VELASCO I, BOEYDEN V, BOSSCHA M, DE VRIES KNOPPERT W, LINDSTEDT, E. RENARDEL DE LAVALETTE VW, VAN DEN BIESEN PR, ALHASSAN M, BAERLAND TP, BOBER AM, FORSAA V, FOSSEN K, VARHAUG P, ATIENZA J.r. NF, CISIECKI S, FRYCZKOWSKI P, KOWAL LANGE A, MICHALEWSKA Z, MICHALEWSKI J, NAWROCKI J, NOWOSIELSKA A, ODROBINA D, PIETRAS TRZPIEL M, ZAKRZEWSKA A, MEIRELES A, TEIXEIRA S, ELSHAFEI M, DANIELESCU C, TALU S, ALTYNBAEV U, GORIN A, SEREJINE I, EL DEEB M, DAVIDOVIC S, IGNJATOVIC Z, STEFANICKOVA J, VENTER L, CHANG W, JO YL, KIM JY, LEE J, LIM ST, SAGONG M, ASCASO FJ, CASTRO J, CORDOVES L. DESCO ESTEBAN C, MORENO MANRESA J, VILAPLANA D, JANIEC S, TOMIC Z, BEN YAHIA S, ACAR N, GÜNGEL H, KAPRAN Z, OSMANBASOGLU O, OZDEK S, TOPBAS S, TOTAN Y, ÜNVER YB, CHICHUR D, DOBROVOLSKEY O, KOZLOVSKA I, LYTVYNCHUK L, PHYLYPCHUK O, POSTOLOVSKA A, SERGIIENKO A, SHEVCHYK V, WINDER S, CULOTTA J, KIM S, KING J, KURUP SK, LIN SJ, PACURARIU R, ROTH D, SINCLAIR S, WEBER P, DOAN H, TUNG T., ROMANO, MARIO, Benmerzouga, N, Metti, F, Razzari, A, Miesbauer, P, Schönherr, U, Zeynalova, Z, Bashir, Sj, Jacob, J, Koch, P, Ladha, R, Smets, E, Stalmans, P, Dare, A, Devenyi, R, Lam, Wc, Shaheeda, M, Potamitis, T, Christensen, Sr, Rayes, E, Mortada, H, Shouman, A, Holm, M, Albinet, P, Amar, Jp, Becquet, F, Berrod, Jp, Boulze, M, Boscher, C, Courjaret, Jc, Denion, E, Fourmaux, E, Guigou, S, Hamon, F, Lafontaine, Po, LE ROUIC, Jf, Leynaud, Jl, Nochez, Y, Perone, Jm, Rysanek, B, Soyeur, R, Bopp, S, Brix, A, Höhn, F, Kusserow, C, Lucke, K, Mohr, A, Schüler, A, Weinberger, A, Gotzaridis, S, Karatzenis, D, Stefaniotou, M, K., TSILIMBARIS MK, Tsouris, D, Tsang, Cw, Gabor, R, Szijarto, Z, Babu, N, Banker, A, Bapaye, M, Kelkar, A, Entezari, M, FATEH MOGHADAM, Hf, Ramezani, A, SAFARPOUR LIMA, B, Omer, K, Boscia, F, CHIARA FRENO, M, Cian, R, Donvito, G, Facino, M, Lesnoni, G, Liuzzi, F, Mete, M, Mininni, F, Mochi, B, Primavera, V, Romano, Mario, Pertile, G, Turco, I, Vastarella, P, Fong, K, Lee, M, VP LOO, A, ARAGON HARRISON, O, FLORES AGUILAR, M, LOPEZ MONTERO, Lm, LOPEZCARASA HERNANDEZ, G, Velasco, I, Boeyden, V, Bosscha, M, DE VRIES KNOPPERT, W, Lindstedt, E., RENARDEL DE LAVALETTE VW, VAN DEN BIESEN, Pr, Alhassan, M, Baerland, Tp, Bober, Am, Forsaa, V, Fossen, K, Varhaug, P, ATIENZA J. r., Nf, Cisiecki, S, Fryczkowski, P, KOWAL LANGE, A, Michalewska, Z, Michalewski, J, Nawrocki, J, Nowosielska, A, Odrobina, D, PIETRAS TRZPIEL, M, Zakrzewska, A, Meireles, A, Teixeira, S, Elshafei, M, Danielescu, C, Talu, S, Altynbaev, U, Gorin, A, Serejine, I, EL DEEB, M, Davidovic, S, Ignjatovic, Z, Stefanickova, J, Venter, L, Chang, W, Jo, Yl, Kim, Jy, Lee, J, Lim, St, Sagong, M, Ascaso, Fj, Castro, J, CORDOVES L., DESCO ESTEBAN C, MORENO MANRESA, J, Vilaplana, D, Janiec, S, Tomic, Z, BEN YAHIA, S, Acar, N, Güngel, H, Kapran, Z, Osmanbasoglu, O, Ozdek, S, Topbas, S, Totan, Y, Ünver, Yb, Chichur, D, Dobrovolskey, O, Kozlovska, I, Lytvynchuk, L, Phylypchuk, O, Postolovska, A, Sergiienko, A, Shevchyk, V, Winder, S, Culotta, J, Kim, S, King, J, Kurup, Sk, Lin, Sj, Pacurariu, R, Roth, D, Sinclair, S, Weber, P, Doan, H, and Tung, T.

Abstract

OBJECTIVE: To study the outcome of the treatment of complex rhegmatogenous retinal detachments (RRDs). DESIGN: Nonrandomized, multicenter, retrospective study. PARTICIPANTS: One hundred seventy-six surgeons from 48 countries spanning 5 continents reported primary procedures for 7678 RRDs. METHODS: Reported data included clinical manifestations, the method of repair, and the outcome. MAIN OUTCOME MEASURES: Failure of retinal detachment repair (level 1 failure rate), remaining silicone oil at the study's conclusion (level 2 failure rate), and need for additional procedures to repair the detachments (level 3 failure rate). RESULTS: The main categories of complex retinal detachments evaluated in this investigation were: (1) grade B proliferative vitreoretinopathy (PVR; n = 917), (2) grade C-1 PVR (n = 637), (3) choroidal detachment or significant hypotony (n = 578), (4) large or giant retinal tears (n = 1167), and (5) macular holes (n = 153). In grade B PVR, the level 1 failure rate was higher when treated with a scleral buckle alone versus vitrectomy (P = 0.0017). In grade C-1 PVR, there was no statistically significant difference in the level 1 failure rate between those treated with vitrectomy, with or without scleral buckle, and those treated with scleral buckle alone (P = 0.7). Vitrectomy with a supplemental buckle had an increased failure rate compared with those who did not receive a buckle (P = 0.007). There was no statistically significant difference in level 1 failure rate between tamponade with gas versus silicone oil in patients with grade B or C-1 PVR. Cases with choroidal detachment or hypotony treated with vitrectomy had a significantly lower failure rate versus treatment with scleral buckle alone (P = 0.0015). Large or giant retinal tears treated with vitrectomy also had a significantly lower failure rate versus treatment with scleral buckle (P = 7×10(-8)). CONCLUSIONS: In patients with retinal detachment, when choroidal detachment, hypotony, a large tear, or a giant tear is present, vitrectomy is the procedure of choice. In retinal detachments with PVR, tamponade with either gas or silicone oil can be considered. If a vitrectomy is to be performed, these data suggest that a supplemental buckle may not be helpful. FINANCIAL DISCLOSURE(S): The author(s) have no proprietary or commercial interest in any materials discussed in this article.

Published
2013

13. Suprachoroidal space in Swept-Source OCT (K)

Author

Michalewska, Z, Michalewski, J, Dulczewska- Cichecka, K, and Nawrocki, J

Subjects
ddc: 610, genetic structures, sense organs, 610 Medical sciences, Medicine, eye diseases
Abstract

Purpose: To define the morphology of outer choroidal margins in swept source optical coherence tomography (SS-OCT). Methods: Prospective observational study of 180 eyes: 20 eyes of healthy volunteers, 20 eyes of myopic patients and 20 eyes from each of the following groups: macular hole (before and[for full text, please go to the a.m. URL], 28. Internationaler Kongress der Deutschen Ophthalmochirurgen

Published
2015
Full Text
View/download PDF

16. How do vitrectomy parameters influence the results of rhegmatogenous retinal detachments repair? EVRS RD Study No. 3

Author

Michalewska Z, Ducournau D, Adelman RA, the EVRS RD Study Group, ROMANO, MARIO, Michalewska, Z, Ducournau, D, Adelman, Ra, the EVRS RD Study, Group, and Romano, Mario

Subjects
Microsurgery, medicine.medical_specialty, business.industry, medicine.medical_treatment, Retinal Detachment, Retinal, Vitrectomy, General Medicine, Prognosis, Ophthalmology, chemistry.chemical_compound, chemistry, Humans, Medicine, business
Published
2013
Full Text
View/download PDF

17. Spectral Optical Coherence Tomography of surgically closed macular holes

Author

Michalewska, Z, Michalewski, J, and Nawrocki, J

Subjects
ddc: 610, genetic structures, sense organs, 610 Medical sciences, Medicine, eye diseases
Abstract

Purpose: To evaluate macular hole morphology after successful vitrectomy. Methods: 68 eyes of 60 patients with a macular hole diagnosed with Spectral OCT underwent pars plana vitrectomy with ILM peeling and air injection. Postoperatively Spectral OCT examinations were performed 1 week, 1 month and[for full text, please go to the a.m. URL], 22. Internationaler Kongress der Deutschen Ophthalmochirurgen

Published
2009
Full Text
View/download PDF

37. Vitrectomy with the inverted internal limiting membrane flap technique in eyes with full-thickness macular hole and dry age-related macular degeneration.

Author

Michalewska Z and Nawrocki J

Subjects
Aged, Basement Membrane surgery, Humans, Retina, Retrospective Studies, Tomography, Optical Coherence, Vitrectomy, Geographic Atrophy, Retinal Perforations surgery
Abstract

Purpose: To present effects of the inverted internal limiting membrane flap technique in full-thickness macular holes coexisting with dry age-related macular degeneration., Methods: Our database was retrospectively reviewed in order to spot patients with the simultaneous diagnosis of dry age-related macular degeneration and full-thickness macular hole. Vitrectomy with the inverted internal limiting membrane flap technique was performed. Inclusion criteria were full-thickness macular hole, drusen, vitrectomy performed, and spectral domain optical coherence tomography (Copernicus HR, Optopol, Poland) or swept source optical coherence tomography (Triton, Topcon, Japan) before surgery, then 1 week (±3 days), 1 month (±1 week), 3 months (±1 month), 6 months (±1 month), 12 months (±2 months), and 18 months to 12 years after surgery., Main Outcome Measures: Closure of macular hole and visual acuity at the final control., Results: A total of 18 eyes of 12 patients (mean age: 68 years) were included. Mean minimum macular hole diameter was 493 μm. Mean maximum macular hole diameter was 1072 μm. Macular hole was closed in 16 eyes after first surgery and in all eyes after second surgery. Improvement of visual acuity was statistically significant ( P  = 0.05), but there was no statistical significant correlation observed between initial macular hole diameters and final visual acuity ( P  > 0.1)., Conclusion: The inverted internal limiting membrane flap technique improves anatomical and functional results in eyes with coexisting dry age-related macular degeneration and full-thickness macular holes. Final development of choroidal neovascularization or geographic atrophy is possible in rare cases.

Published
2021
Full Text
View/download PDF

39. Fovea Morphology After Vitrectomy in Eyes With Full-Thickness Macular Hole Coexisting With Diabetic Retinopathy.

Author

Michalewska Z and Nawrocki J

Abstract

Purpose: This work presents the effects of vitrectomy with an inverted internal limiting membrane flap in full-thickness macular holes (FTMHs) in eyes with diabetic retinopathy (DR)., Methods: Vitrectomy with the inverted and temporal inverted internal limiting membrane flap technique was performed in all cases. Inclusion criteria were FTMH, diabetes treated with oral drugs or with insulin for at least 5 years, spectral-domain or swept-source optical coherence tomography performed before surgery then 1 week, 1, 3, 6, 12, and 18 to 36 months after surgery., Results: FTMH with nonproliferative DR (NPDR) was noted in 20 eyes and with proliferative DR (PDR) in 5 eyes. In PDR the margins of the macular holes (MHs) were always detached, and the MHs tended to be larger than in NPDR. The minimum diameter-to-base diameter ratio was 1:2 in NPDR and 1:10 in PDR. Postoperatively central retinal thickness and visual acuity (VA) were significantly lower for PDR. Twenty-one of 25 FTMHs were closed after the first surgery, and all were closed after the second surgery. VA improved, final results did not depend on FTMH diameter. Photoreceptor defects decreased in size but were present in all cases 12 months after surgery., Conclusions: Morphology of MHs in NPDR and PDR was varied. FTMH in NPDR resembled idiopathic cases; morphology of FTMH with PDR was different. In PDR, FTMHs were larger and the fovea was usually detached; retina thinning was also observed. Final VA depended on initial VA and the severity of the disease (NPDR vs PDR)., Competing Interests: The author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article., (© The Author(s) 2020.)

Published
2020
Full Text
View/download PDF

40. [Untitled]

Author

Michalewska Z, Nawrocka Z, and Nawrocki J

Subjects
Humans, Tomography, Optical Coherence, Eye Abnormalities, Vitrectomy
Published
2020
Full Text
View/download PDF

41. Swept-Source OCT and Swept-Source OCT Angiography before and after Vitrectomy with Stuffing of the Optic Pit.

Author

Michalewska Z, Nawrocka Z, and Nawrocki J

Subjects
Adolescent, Adult, Female, Follow-Up Studies, Fundus Oculi, Humans, Macular Degeneration surgery, Male, Middle Aged, Optic Disk diagnostic imaging, Prospective Studies, Young Adult, Fluorescein Angiography methods, Macular Degeneration diagnosis, Optic Disk abnormalities, Tomography, Optical Coherence methods, Vitrectomy methods
Abstract

Purpose: To identify swept-source (SS) OCT and SS OCT angiography (OCTA) patterns predicting outcome in patients with optic disc pit-associated maculopathy and to present the results of a novel surgical technique, stuffing of the optic disc pit., Design: Prospective, interventional study., Participants: Fifteen eyes., Methods: Swept-source OCT before surgery and then 1 week and 1, 3, and 6 months after surgery, then up to 4 years later. Swept-source OCTA was performed from 2015 (9 patients). After core vitrectomy, internal limiting membrane (ILM) was peeled between the optic nerve and fovea and stuffed into the optic disc pit. Laser photocoagulation was performed at the temporal side of the optic disc pit. Fluid-air exchange followed. The following data were noted: visual acuity, central retinal thickness, distribution of fluid on SS OCT, and diameters and circuit of the foveal avascular zone on OCTA., Main Outcome Measures: Normalization of the fovea contour and visual acuity., Results: We subdivided patients into 2 groups. On SS OCT, we observed subretinal fluid with elevation of the fovea (group 1) in 8 eyes. Group 2 comprised 7 eyes without subretinal fluid, but with intraretinal fluid. Five of these eyes additionally showed an outer lamellar macular hole. Anatomic success was achieved in all eyes. The decrease of central retinal thickness 1 week after surgery was more marked in group 1 (P = 0.002). The area of the foveal avascular zone in the superficial retinal vessel layer increased significantly after surgery for group 2 (P = 0.04), but not for group 1 (P = 0.4). Visual acuity improved without statistically significant differences between groups., Conclusions: Stuffing of the optic disc pit with the ILM results in improvement of anatomic and functional results. Prognosis depends on initial morphologic features. Central retinal thickness normalizes faster after surgery in eyes with subretinal fluid when compared with eyes with intraretinal fluid. Faster anatomic improvement does not correlate with improvement of vision. Postoperative increase in the size of the foveal avascular zone in the superficial retinal vessel layer, more pronounced in group 2, may be associated with the prolonged postoperative anatomic recovery in those eyes., (Copyright © 2020 American Academy of Ophthalmology. Published by Elsevier Inc. All rights reserved.)

Published
2020
Full Text
View/download PDF

42. UNDERDIAGNOSED OPTIC DISK PIT MACULOPATHY: Spectral Domain Optical Coherence Tomography Features For Accurate Diagnosis.

Author

Iglicki M, Busch C, Loewenstein A, Fung AT, Invernizzi A, Mariussi M, Arias R, Gabrielle PH, Cebeci Z, Okada M, Nawrocki J, Michalewska Z, Goldstein M, Barak A, and Zur D

Subjects
Adolescent, Adult, Aged, Aged, 80 and over, Eye Abnormalities complications, Female, Humans, Macular Degeneration etiology, Male, Middle Aged, Optic Disk pathology, Reproducibility of Results, Retrospective Studies, Young Adult, Eye Abnormalities pathology, Macula Lutea pathology, Macular Degeneration diagnosis, Optic Disk abnormalities, Tomography, Optical Coherence methods
Abstract

Purpose: To report a cohort with optic disk pit maculopathy (ODPM) presenting with neurosensory macular detachment that were initially misdiagnosed and mistreated; and to describe structural features on spectral domain optical coherence tomography in misdiagnosed and all other consecutive cases of ODPM., Methods: Multicenter international retrospective cohort study., Participants: 59 eyes from 59 patients with ODPM., Main Outcome Measures: 1) Proportion of patients with ODPM initially misdiagnosed, inaccurate diagnosis and treatment. 2) Morphologic features on spectral domain optical coherence tomography: other causes of subretinal and/or intraretinal fluid, inner/outer retinoschisis, communication with optic disk pit, and retinal pigment epithelium alterations. 3) Visual and anatomical outcomes 6 months after proper treatment., Results: Fifteen patients (25.4%) with ODPM were correctly diagnosed initially and those were significantly younger than misdiagnosed cases (age 33.8 ± 15.2 vs. 58.7 ± 15.8 years, P < 0.0001). Forty of forty-four misdiagnosed eyes (90.9%) were treated for their presumed diagnosis before referral. Eyes with initial misdiagnosis had significantly more outer retinoschisis at baseline (88.4 vs. 40.0%, P = 0.0002) and more retinal pigment epithelium alterations (90.0 vs. 27.3%, P < 0.0001) 6 months after proper treatment., Conclusion: Optic disk pit maculopathy is an underdiagnosed entity and can mimic other causes for subretinal fluid. Awareness and identification of pertinent spectral domain optical coherence tomography features can help avoid inappropriate and delayed treatment.

Published
2019
Full Text
View/download PDF

43. Antivascular Endothelial Growth Factor Treatment Might Be Continued Even After Vitrectomy for Endophthalmitis in Neovascular Age-Related Macular Degeneration.

Author

Michalewska Z and Nawrocki J

Abstract

Purpose: This article studies visual outcome and frequency of antivascular endothelial growth factor (anti-VEGF) injections continued in patients with neovascular age-related macular degeneration (AMD) who had an earlier vitrectomy for postinjection endophthalmitis., Methods: A retrospective interventional study was conducted reviewing our database for patients with a diagnosis of endophthalmitis in the course of anti-VEGF injections. Endophthalmitis diagnosis was made on clinical examination of pain, rapid decrease in visual acuity (VA), conjunctival hyperemia, hypopyon, and vitritis. In all eyes, core vitrectomy with intravitreal antibiotics was performed. Spectral-domain optical coherence tomography was performed monthly before and after surgery during follow-up. Anti-VEGF injections were continued after surgery in all cases., Results: Eight eyes with postinjection endophthalmitis were included. Mean VA immediately before endophthalmitis was 20/50 Snellen with a mean of 19 intravitreal anti-VEGF injections ( P = .45). At time of endophthalmitis diagnosis, mean VA was 20/1000 (range, 20/2000-20/200). Mean time from injection to when the patient noted first symptoms was 4.3 days (range, 1-8 days). Mean time from first symptoms to surgery was 12 hours (range, 2.5-26 hours). Final mean VA at the end of follow-up (range, 12-84 months) did not statistically differ from VA at the visit immediately before endophthalmitis diagnosis ( P = .69). Mean frequency of injections after vitrectomy did not significantly differ from the presurgical course of treatment ( P =.97)., Conclusions: Anti-VEGF treatment might be continued after vitrectomy for endophthalmitis and results in satisfactory anatomical and visual outcome. Surgery did not influence the frequency of anti-VEGF injections for neovascular AMD., Competing Interests: The author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article., (© The Author(s) 2019.)

Published
2019
Full Text
View/download PDF

44. Letter to the editor relating to Lytvynchuk LM, Falkner-Radler CI, Krepler K, Glittenberg CG, Ahmed D et al.: "Dynamic intraoperative optical coherence tomography for inverted internal limiting membrane flap technique in large macular hole surgery" Graefes Arch Clin Exp Ophthalmol 2019 May 29; https://doi.org/10.1007/s00417-019-04364-5 [Epub ahead of print].

Author

Michalewska Z and Nawrocki J

Subjects
Humans, Retina, Tomography, Optical Coherence, Vitrectomy, Retinal Detachment surgery, Retinal Perforations surgery
Published
2019
Full Text
View/download PDF

46. International Practice Patterns for the Management of Acute Postsurgical and Postintravitreal Injection Endophthalmitis: European Vitreo-Retinal Society Endophthalmitis Study Report 1.

Author

Soliman MK, Gini G, Kuhn F, Iros M, Parolini B, Ozdek S, Michalewska Z, Bopp S, Adelman RA, and Sallam AB

Subjects
Aged, Angiogenesis Inhibitors administration & dosage, Anti-Bacterial Agents administration & dosage, Disease Management, Endophthalmitis epidemiology, Endophthalmitis etiology, Europe epidemiology, Eye Infections, Bacterial epidemiology, Eye Infections, Bacterial etiology, Female, Follow-Up Studies, Humans, Incidence, Intravitreal Injections adverse effects, Male, Middle Aged, Ophthalmology, Practice Guidelines as Topic, Retrospective Studies, Societies, Medical, Surgical Wound Infection epidemiology, Surgical Wound Infection etiology, Angiogenesis Inhibitors adverse effects, Antibiotic Prophylaxis standards, Cataract Extraction adverse effects, Endophthalmitis therapy, Eye Infections, Bacterial therapy, Surgical Wound Infection therapy, Vitrectomy standards
Abstract

Purpose: To study the practice patterns for the management of acute postoperative and postinjection endophthalmitis., Design: Retrospective, interventional, nonrandomized, multicenter study., Participants: Data on 237 eyes diagnosed with acute endophthalmitis occurring after intraocular surgery or procedures provided by 57 retina specialists from 28 countries., Main Outcome Measures: Rates of pars plana vitrectomy (PPV), repeat intravitreal injection, and adjunctive therapeutic regimens (local and systemic antibiotics and steroids)., Results: Of 237 analyzed eyes, acute endophthalmitis secondary to cataract surgery or secondary lens implantation represented 64.6% of cases (153 eyes), whereas the remaining were secondary to intravitreal injections (35 eyes [14.8%]), PPV (29 eyes [12.2%]), and other intraocular surgeries (20 eyes [8.4%]). All eyes received intravitreal antibiotics on the same day of diagnosis. Overall, early PPV was used within the first week of presentation in 176 eyes (74.3%). There was no statistical difference in the proportion of eyes requiring a second intravitreal injection of antibiotics whether the eye was managed primarily with intravitreal antibiotics alone versus early PPV plus intravitreal antibiotics (29.5% [18 eyes] vs. 25.0% [44 eyes], respectively). Adjunctive therapies in the form of intravitreal steroids, systemic steroids, and systemic antibiotics were used in 25.3%, 21.9%, and 66.6% of eyes, respectively. The absence of disc or macular view and absence of endophthalmitis after cataract surgery were associated with an increased likelihood for early PPV (odds ratios 4.1 and 5.1, respectively)., Conclusions: Pars plana vitrectomy was frequently performed regardless of the presenting vision in eyes with endophthalmitis after cataract surgery and intravitreal injections. Increased vitreous opacification was associated with a higher probability for performing PPV., (Copyright © 2019 American Academy of Ophthalmology. Published by Elsevier Inc. All rights reserved.)

Published
2019
Full Text
View/download PDF

47. Correspondence.

Author

Nawrocki J, Michalewska Z, and Adelman RA

Subjects
Humans, Retina, Surgical Flaps, Retinal Perforations
Published
2018
Full Text
View/download PDF

48. MECHANISM OF "FLAP CLOSURE" AFTER THE INVERTED INTERNAL LIMITING MEMBRANE FLAP TECHNIQUE.

Author

Bonińska K, Nawrocki J, and Michalewska Z

Subjects
Adolescent, Adult, Aged, Aged, 80 and over, Child, Female, Follow-Up Studies, Humans, Male, Middle Aged, Retinal Perforations diagnosis, Retrospective Studies, Tomography, Optical Coherence, Young Adult, Basement Membrane transplantation, Fovea Centralis pathology, Retinal Perforations surgery, Surgical Flaps, Visual Acuity, Vitrectomy methods
Abstract

Purpose: Recent studies described that in approximately 14% to 16% of cases of macular holes treated with the inverted internal limiting membrane flap technique, the hole was closed only by a thin layer of inverted internal limiting membrane-"flap closure." The aim of this article was to describe the functional and anatomical results in flap closure macular holes and also the mechanism of flap closure., Methods: A retrospective observational study of 149 eyes of 139 patients treated with vitrectomy using the inverted internal limiting membrane flap technique was reviewed to aggregate eyes with flap closure. Complete ophthalmic examination was performed preoperatively and at 7 days, 1, 3, 6, and 12 months after surgery., Results: Flap closure (Group 1) was noted in 24 eyes and other closure types in 125 eyes (Group 2). The mean minimal and base diameters of the macular holes in the flap closure group were greater than those in Group 2 (P < 0.001). The mean postoperative best-corrected visual acuity in the flap closure group (20/100) was lower than that in Group 2 (20/50) (P < 0.001)., Conclusion: Flap closure probably enables closure of large macular holes with a higher probability of remaining open without the use of the inverted internal limiting membrane flap technique. Foveal architecture continuously improved.

Published
2018
Full Text
View/download PDF

50. SWEPT-SOURCE OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY REVEALS INTERNAL LIMITING MEMBRANE PEELING ALTERS DEEP RETINAL VASCULATURE.

Author

Michalewska Z and Nawrocki J

Subjects
Aged, Choroid blood supply, Female, Follow-Up Studies, Fovea Centralis blood supply, Fundus Oculi, Humans, Male, Prospective Studies, Retinal Perforations diagnosis, Time Factors, Basement Membrane surgery, Fluorescein Angiography methods, Retinal Perforations surgery, Retinal Vessels diagnostic imaging, Tomography, Optical Coherence methods, Visual Acuity, Vitrectomy methods
Abstract

Purpose: To describe morphology of retinal and choroidal vessels in swept-source optical coherence tomography angiography before and after vitrectomy with the temporal inverted internal limiting membrane (ILM) flap technique for full-thickness macular holes., Methods: Prospective, observational study of 36 eyes of 33 patients with full-thickness macular holes swept-source optical coherence tomography angiography was performed in patients before and 1 month after vitrectomy. Vitrectomy with the temporal inverted ILM flap technique was performed. In this method, ILM is peeled only at one side of the fovea. An ILM flap is created to cover the macular hole. Comparison of retina vasculature in the areas of ILM peeling vs. no ILM peeling at 1 and 3 months after successful vitrectomy was performed., Results: The study demonstrated lower density of vessels in the deep retinal plexus in the area where ILM was peeled as compared to the rest of the fovea. Visual acuity and central retinal thickness 1 month after surgery correlates with fovea avascular zone diameter in deep retinal layers at the same time point (P = 0.001)., Conclusion: This study confirmed that ILM peeling might alter blood flow in deep retinal vessels below the peeling area in the early postoperative period. The area of the fovea avascular zone corresponds to functional results at the same time point.

Published
2018
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results