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1,636 results on '"MISHIMA, Michiaki"'

3. FLUCTUATIONS, NOISE AND SCALING IN THE CARDIO-PULMONARY SYSTEM

Author

SUKI, BÉLA, primary, ALENCAR, ADRIANO M., additional, FREY, URS, additional, IVANOV, PLAMEN CH., additional, BULDYREV, SERGEY V., additional, MAJUMDAR, ARNAB, additional, STANLEY, H. EUGENE, additional, DAWSON, CHRISTOPHER A., additional, KRENZ, GARY S., additional, and MISHIMA, MICHIAKI, additional

Published
2022
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4. Aquaporin-3 potentiates allergic airway inflammation in ovalbumin-induced murine asthma.

Author

Ikezoe, Kohei, Oga, Toru, Honda, Tetsuya, Hara-Chikuma, Mariko, Ma, Xiaojun, Tsuruyama, Tatsuaki, Uno, Kazuko, Fuchikami, Jun-Ichi, Tanizawa, Kiminobu, Handa, Tomohiro, Taguchi, Yoshio, Verkman, Alan S, Narumiya, Shuh, Mishima, Michiaki, and Chin, Kazuo

Subjects
Lymph Nodes, Spleen, CD4-Positive T-Lymphocytes, Macrophages, Alveolar, Bronchoalveolar Lavage Fluid, Animals, Mice, Inbred C57BL, Asthma, Pneumonia, Hypersensitivity, Hydrogen Peroxide, Ovalbumin, RNA, Messenger, Chemokines, Cell Count, Cell Membrane Permeability, Gene Expression Regulation, Aquaporin 3, Macrophages, Alveolar, Mice, Inbred C57BL, RNA, Messenger
Abstract

Oxidative stress plays a pivotal role in the pathogenesis of asthma. Aquaporin-3 (AQP3) is a small transmembrane water/glycerol channel that may facilitate the membrane uptake of hydrogen peroxide (H2O2). Here we report that AQP3 potentiates ovalbumin (OVA)-induced murine asthma by mediating both chemokine production from alveolar macrophages and T cell trafficking. AQP3 deficient (AQP3(-/-)) mice exhibited significantly reduced airway inflammation compared to wild-type mice. Adoptive transfer experiments showed reduced airway eosinophilic inflammation in mice receiving OVA-sensitized splenocytes from AQP3(-/-) mice compared with wild-type mice after OVA challenge, consistently with fewer CD4(+) T cells from AQP3(-/-) mice migrating to the lung than from wild-type mice. Additionally, in vivo and vitro experiments indicated that AQP3 induced the production of some chemokines such as CCL24 and CCL22 through regulating the amount of cellular H2O2 in M2 polarized alveolar macrophages. These results imply a critical role of AQP3 in asthma, and AQP3 may be a novel therapeutic target.

Published
2016

10. One-day systemic corticosteroid administration for asthma and future “short bursts” risk in real clinical practice

Author

Matsumoto, Takeshi, primary, Kaneko, Akiko, additional, Fujiki, Takahiro, additional, Kusakabe, Yusuke, additional, Nakayama, Emi, additional, Tanaka, Ayaka, additional, Yamamoto, Naoki, additional, Tashima, Mayuko, additional, Ito, Chikara, additional, Aihara, Kensaku, additional, Yamaoka, Shinpachi, additional, and Mishima, Michiaki, additional

Published
2023
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13. The long-term outcome of interstitial lung disease with anti-aminoacyl-tRNA synthetase antibodies

Author

Tanizawa, Kiminobu, Handa, Tomohiro, Nakashima, Ran, Kubo, Takeshi, Hosono, Yuji, Watanabe, Kizuku, Aihara, Kensaku, Ikezoe, Kohei, Sokai, Akihiko, Nakatsuka, Yoshinari, Taguchi, Yoshio, Hatta, Kazuhiro, Noma, Satoshi, Kobashi, Yoichiro, Yoshizawa, Akihiko, Oga, Toru, Hirai, Toyohiro, Chin, Kazuo, Nagai, Sonoko, Izumi, Takateru, Mimori, Tsuneyo, and Mishima, Michiaki

Published
2017
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15. Staphylococcus aureus enterotoxin sensitization involvement and its association with the CysLTR1 variant in different asthma phenotypes

Author

Matsumoto, Hisako, Kanemitsu, Yoshihiro, Nagasaki, Tadao, Tohda, Yuji, Horiguchi, Takahiko, Kita, Hideo, Kuwabara, Kazunobu, Tomii, Keisuke, Otsuka, Kojiro, Fujimura, Masaki, Ohkura, Noriyuki, Tomita, Katsuyuki, Yokoyama, Akihito, Ohnishi, Hiroshi, Nakano, Yasutaka, Oguma, Tetsuya, Hozawa, Soichiro, Izuhara, Yumi, Ito, Isao, Oguma, Tsuyoshi, Inoue, Hideki, Tajiri, Tomoko, Iwata, Toshiyuki, Ono, Junya, Ohta, Shoichiro, Hirota, Tomomitsu, Kawaguchi, Takahisa, Tamari, Mayumi, Yokoyama, Tetsuji, Tabara, Yasuharu, Matsuda, Fumihiko, Izuhara, Kenji, Niimi, Akio, and Mishima, Michiaki

Published
2017
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20. Supplementary Figures 1 - 5 from Druggable Oncogene Fusions in Invasive Mucinous Lung Adenocarcinoma

Author

Nakaoku, Takashi, primary, Tsuta, Koji, primary, Ichikawa, Hitoshi, primary, Shiraishi, Kouya, primary, Sakamoto, Hiromi, primary, Enari, Masato, primary, Furuta, Koh, primary, Shimada, Yoko, primary, Ogiwara, Hideaki, primary, Watanabe, Shun-ichi, primary, Nokihara, Hiroshi, primary, Yasuda, Kazuki, primary, Hiramoto, Masaki, primary, Nammo, Takao, primary, Ishigame, Teruhide, primary, Schetter, Aaron J., primary, Okayama, Hirokazu, primary, Harris, Curtis C., primary, Kim, Young Hak, primary, Mishima, Michiaki, primary, Yokota, Jun, primary, Yoshida, Teruhiko, primary, and Kohno, Takashi, primary

Published
2023
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21. Supplementary Materials and Methods from Druggable Oncogene Fusions in Invasive Mucinous Lung Adenocarcinoma

Author

Nakaoku, Takashi, primary, Tsuta, Koji, primary, Ichikawa, Hitoshi, primary, Shiraishi, Kouya, primary, Sakamoto, Hiromi, primary, Enari, Masato, primary, Furuta, Koh, primary, Shimada, Yoko, primary, Ogiwara, Hideaki, primary, Watanabe, Shun-ichi, primary, Nokihara, Hiroshi, primary, Yasuda, Kazuki, primary, Hiramoto, Masaki, primary, Nammo, Takao, primary, Ishigame, Teruhide, primary, Schetter, Aaron J., primary, Okayama, Hirokazu, primary, Harris, Curtis C., primary, Kim, Young Hak, primary, Mishima, Michiaki, primary, Yokota, Jun, primary, Yoshida, Teruhiko, primary, and Kohno, Takashi, primary

Published
2023
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22. Supplementary Figure Legends from Druggable Oncogene Fusions in Invasive Mucinous Lung Adenocarcinoma

Author

Nakaoku, Takashi, primary, Tsuta, Koji, primary, Ichikawa, Hitoshi, primary, Shiraishi, Kouya, primary, Sakamoto, Hiromi, primary, Enari, Masato, primary, Furuta, Koh, primary, Shimada, Yoko, primary, Ogiwara, Hideaki, primary, Watanabe, Shun-ichi, primary, Nokihara, Hiroshi, primary, Yasuda, Kazuki, primary, Hiramoto, Masaki, primary, Nammo, Takao, primary, Ishigame, Teruhide, primary, Schetter, Aaron J., primary, Okayama, Hirokazu, primary, Harris, Curtis C., primary, Kim, Young Hak, primary, Mishima, Michiaki, primary, Yokota, Jun, primary, Yoshida, Teruhiko, primary, and Kohno, Takashi, primary

Published
2023
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23. Supplementary Tables 1 - 2 from Druggable Oncogene Fusions in Invasive Mucinous Lung Adenocarcinoma

Author

Nakaoku, Takashi, primary, Tsuta, Koji, primary, Ichikawa, Hitoshi, primary, Shiraishi, Kouya, primary, Sakamoto, Hiromi, primary, Enari, Masato, primary, Furuta, Koh, primary, Shimada, Yoko, primary, Ogiwara, Hideaki, primary, Watanabe, Shun-ichi, primary, Nokihara, Hiroshi, primary, Yasuda, Kazuki, primary, Hiramoto, Masaki, primary, Nammo, Takao, primary, Ishigame, Teruhide, primary, Schetter, Aaron J., primary, Okayama, Hirokazu, primary, Harris, Curtis C., primary, Kim, Young Hak, primary, Mishima, Michiaki, primary, Yokota, Jun, primary, Yoshida, Teruhiko, primary, and Kohno, Takashi, primary

Published
2023
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24. Supplementary Table Legends from Druggable Oncogene Fusions in Invasive Mucinous Lung Adenocarcinoma

Author

Nakaoku, Takashi, primary, Tsuta, Koji, primary, Ichikawa, Hitoshi, primary, Shiraishi, Kouya, primary, Sakamoto, Hiromi, primary, Enari, Masato, primary, Furuta, Koh, primary, Shimada, Yoko, primary, Ogiwara, Hideaki, primary, Watanabe, Shun-ichi, primary, Nokihara, Hiroshi, primary, Yasuda, Kazuki, primary, Hiramoto, Masaki, primary, Nammo, Takao, primary, Ishigame, Teruhide, primary, Schetter, Aaron J., primary, Okayama, Hirokazu, primary, Harris, Curtis C., primary, Kim, Young Hak, primary, Mishima, Michiaki, primary, Yokota, Jun, primary, Yoshida, Teruhiko, primary, and Kohno, Takashi, primary

Published
2023
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38. Age-Related Changes in the Trachea in Healthy Adults

Author

Sakai, Hiroaki, Nakano, Yasutaka, Muro, Shigeo, Hirai, Toyohiro, Takubo, Yasutaka, Oku, Yoshitaka, Hamakawa, Hiroshi, Takahashi, Ayuko, Sato, Toshihiko, Chen, Fengshi, Sahara, Hisashi, Fujinaga, Takuji, Sato, Kiyoshi, Sonobe, Makoto, Shoji, Tsuyoshi, Miyahara, Ryo, Okubo, Kenichi, Bando, Toru, Hirata, Toshiki, Date, Hiroshi, Mishima, Michiaki, Takahashi, Eiji, editor, and Bruley, Duane F., editor

Published
2010
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44. Risk factors for stomatitis in patients with lymphangioleiomyomatosis during treatment with sirolimus: A multicenter investigator‐initiated prospective study

Author

Kitamura, Nobutaka, Seyama, Kuniaki, Inoue, Yoshikazu, Nagai, Katsura, Suzuki, Masaru, Moriyama, Hiroshi, Takada, Toshinori, Tazawa, Ryushi, Hirai, Toyohiro, Mishima, Michiaki, Hayashida, Mie, Hirose, Masaki, Arai, Toru, Sugimoto, Chikatoshi, Hattori, Noboru, Watanabe, Kentaro, Tamada, Tsutomu, Akazawa, Kohei, Tanaka, Takahiro, and Nakata, Koh

Published
2017
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47. A nationwide epidemiological survey of chronic hypersensitivity pneumonitis in Japan

Author

Okamoto, Tsukasa, Miyazaki, Yasunari, Ogura, Takashi, Chida, Kingo, Kohno, Nobuoki, Kohno, Shigeru, Taniguchi, Hiroyuki, Akagawa, Shinobu, Mochizuki, Yoshiro, Yamauchi, Kohei, Takahashi, Hiroki, Johkoh, Takeshi, Homma, Sakae, Kishi, Kazuma, Ikushima, Soichiro, Konno, Satoshi, Mishima, Michiaki, Ohta, Ken, Nishioka, Yasuhiko, Yoshimura, Nobuyuki, Munakata, Mitsuru, Watanabe, Kentaro, Miyashita, Yoshihiro, and Inase, Naohiko

Published
2013
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