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45 results on '"MOHR, CATHERINE A."'

3. Invasive fungal infections in patients with haematological malignancies at the University Hospital of Reunion Island (2018–2022): An observational study.

Author

Estagnasié, Camille, Mohr, Catherine, Kamus, Laure, Zunic, Patricia, Chirpaz, Emmanuel, Moiton, Marie-Pierre, and Lagrange-Xelot, Marie

Abstract

Invasive fungal infections are a serious complication for haematology patients. However, there is no study on this subject in Reunion Island. The aim of this study was to estimate the incidence of invasive fungal infections in patients with haematological malignancies at the University Hospital of Reunion Island. We conducted a descriptive and ambispective study. We included any patient with haematological malignancy presenting with a putative, possible, probable, or proven invasive fungal infection, defined as per the criteria of the European Organisation for Research and Treatment of Cancer/Mycoses Study Group 2019, from January 2018 to December 2022. Data were collected from medical records and identified by ICD-10 coding and laboratory data. Eighty-nine invasive fungal infections were diagnosed in 76 patients. The 5-year incidence rate of invasive fungal infections was 1.7 per 100 person-years (95% Confidence Interval (CI) 1.3–2). Invasive aspergillosis was the most common infection (35/89, 39%), followed by invasive candidiasis (33/89, 37%), mucormycosis (7/89, 8%), and pneumocystosis (7/89, 8%). Most infections occurred in patients with acute myeloid leukaemia (32/89, 36%) and lymphoma (26/89, 29%). Six-month mortality was higher for mucormycosis (71%) than for aspergillosis (34%) and invasive candidiasis (33%). The incidence and distribution of fungal infections in haematology patients were similar to European cohorts, albeit with more mucormycosis, less pneumocystis, and a high proportion of Candida parapsilosis in candidemia. [ABSTRACT FROM AUTHOR]

Published
2024
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7. Risk Factors for Steroid-Refractory Acute Graft-versus-Host Disease after Allogeneic Stem Cell Transplantation from Matched Related or Unrelated Donors

Author

Calmettes, Claire, Vigouroux, Stéphane, Labopin, Myriam, Tabrizi, Reza, Turlure, Pascal, Lafarge, Xavier, Marit, Gérald, Pigneux, Arnaud, Leguay, Thibaut, Bouabdallah, Krimo, Dilhuydy, Marie-Sarah, Duclos, Cédric, Mohr, Catherine, Lascaux, Axelle, Dumas, Pierre-Yves, Dimicoli-Salazar, Sophie, Saint-Lézer, Arnaud, and Milpied, Noël

Published
2015
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9. Network

Author

Mohr, Catherine Jane, Liverneaux, Philippe A., editor, Berner, Stacey H., editor, Bednar, Michael S., editor, Parekattil, Sijo J., editor, Mantovani Ruggiero, Gustavo, editor, and Selber, Jesse C., editor

Published
2013
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10. Comparison of Outcomes after Two Standards-of-Care Reduced-Intensity Conditioning Regimens and Two Different Graft Sources for Allogeneic Stem Cell Transplantation in Adults with Hematologic Diseases: A Single-Center Analysis

Author

Le Bourgeois, Amandine, Mohr, Catherine, Guillaume, Thierry, Delaunay, Jacques, Malard, Florent, Loirat, Marion, Peterlin, Pierre, Blin, Nicolas, Dubruille, Viviane, Mahe, Beatrice, Gastinne, Thomas, Le Gouill, Steven, Moreau, Philippe, Mohty, Mohamad, Planche, Lucie, Lode, Laurence, Bene, Marie-Christine, and Chevallier, Patrice

Published
2013
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17. Filtration Efficiency, Breathability, and Reusability of Improvised Materials for Face Masks

Author

Loibl, Rebecca, Gorrepati, Madhu, Mohr, Catherine, Manzo, Scott, Mehendale, Shilpa, Azizi, Arad, Khalaji, Iman, Bagheri, Morteza, and Schiffres, Scott

Subjects
engrXiv|Engineering|Biomedical Engineering and Bioengineering, engrXiv|Engineering, bepress|Engineering, bepress|Engineering|Mechanical Engineering, engrXiv|Engineering|Mechanical Engineering, technology, industry, and agriculture, bepress|Engineering|Biomedical Engineering and Bioengineering, bepress|Engineering|Materials Science and Engineering, engrXiv|Engineering|Materials Science and Engineering
Abstract

The goal of this study is to evaluate the filtration efficiency and breathability of improvised filtration and commonly available mask materials, as well as to assess their reusability. Materials readily available to the general public such as cotton, fragrance and additive-free dry baby cleaning wipes, and those abundantly available in the hospital setting, such as sterilization wraps, were chosen for testing, amongst others. In the COVID-important 2–5 micron particle range, two-layers of cotton provided filtration efficiency between 34%–66%. Amongst potential filter materials, 300-weight sterilization wraps provided approximately 80% filtration efficiency and are readily available in the healthcare setting. The addition of sterilization wrap to cotton fabrics brought the filtration efficiency to above that of the sterilization wrap (80%-90%) at the expense of added pressure drop. Four-layers of dry baby wipes performed very well with a filtration efficiency of 85% and a reasonable pressure drop (1/3 of procedure mask). Since the material is advertised as pure spunlace polypropylene and designed to contact the skin during cleaning, it would appear generally safe as a filter insert. Of improvised filters, polypropylene electrostatic HVAC filters performed the best with filtration efficiencies of >99%, but are not recommended due to the risk of confusion with glass-based HVAC filters and uncertainty regarding trace materials used in the filter. The filtration efficiency of two-layers of cotton fabrics with one-layer of sterilization wrap slightly improved over 10 laundry cycles, while the performance of other non-wovens, like dry baby wipes, degraded more rapidly and should be considered disposable. In summary, we found that two-layers of cotton fabric can provide a comfortable, breathable and reusable option. The addition of a sterilization wrap or four-layers of pure spunlace fragrance free dry baby wipes can significantly improve filtration and block expiratory aerosols at the expense of an added pressure drop.

Published
2020
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25. Clinical Spectrum, Long-Term Outcomes and Predictors of Relapse after Imatinib Discontinuation in FIP1L1-Pdgfra-Associated Chronic Eosinophilic Leukemia: Data from 150 Patients

Author

Rohmer, Julien, primary, Groh, Matthieu, primary, Trichereau, Julie, primary, Panel, Kewin, primary, Preudhomme, Claude, primary, Legrand, Fanny, primary, Ackermann, Felix, primary, Couteau-Chardon, Amélie, primary, Ebbo, Mikael, primary, Fain, Olivier, primary, Galicier, Lionel, primary, Hamidou, Mohamed, primary, Hunault, Mathilde, primary, Lengline, Etienne, primary, Mohr, Catherine, primary, Nicolini, Franck E, primary, Rey, Jerome, primary, Terriou, Louis, primary, Morati Hafsaoui, Chafika, primary, Tavitian, Suzanne, primary, Machelart, Irene, primary, Jondeau, Katayoun, primary, Arnulf, Bertrand, primary, Ianotto, Jean-Christophe, primary, Zini, Jean-Marc, primary, Dubruille, Viviane, primary, Huguet, Francoise, primary, Slama, Borhane, primary, Jardin, Fabrice, primary, Adiko, Didier, primary, Toussaint, Elise, primary, Guffroy, Aurelien, primary, Lhomme, Faustine, primary, Grardel, Nathalie, primary, Gesquieres, Cyrielle, primary, Lefèvre, Guillaume, primary, and Kahn, Jean Emmanuel, primary

Published
2019
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26. Histologic analysis has a prognostical value in colorectal biopsies assessed for suspicion of graft-versus-host disease

Author

Sauvestre, Fanny, primary, Belleannée, Geneviève, additional, Bréal, Claire, additional, Mohr, Catherine, additional, Fong, Harold IpKan, additional, Cossin, Sébastien, additional, Tabrizi, Reza, additional, Milpied, Noël, additional, Vigouroux, Stéphane, additional, Goussot, Jean-François, additional, and Marty, Marion, additional

Published
2017
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27. Fertility Considerations in Laparoscopic Treatment of Infiltrative Bowel Endometriosis

Author

Mohr, Catherine, Nezhat, Farr R., Nezhat, Ceana H., Seidman, Daniel S., and Nezhat, Camran R.

Subjects
Adult, Intestinal Diseases, Bowel endometriosis, Infertility, Scientific Papers, Endometriosis, Humans, Laparoscopy, Female, Middle Aged, Infertility, Female, Retrospective Studies
Abstract

Objective: The purpose of this study was to examine our experience with laparoscopic and laparoscopically assisted management of bowel endometriosis and to recommend treatment approaches, considering patient goals for both pain mitigation or fertility, or both. Methods: The medical records of 187 women treated laparoscopically for intestinal endometriosis were reviewed retrospectively for presenting symptoms, methods of surgical treatment, complications, and efficacy of treating pain and infertility. The extent of resection was determined by the severity of the endometriotic lesion, tempered by the patient's fertility goals. Results: The most common patient complaint preceding surgery was pelvic pain. In addition, 58 (31%) patients experienced impaired fertility. Of the patients available for long-term follow-up, 152 (85%) reported complete or significant long-term pain relief. Complete pain relief in the immediate postoperative period was significantly more likely with partial bowel resection compared with shaving only, 92% vs 80%, respectively, P

Published
2005

29. Transient Grades 3 to 4 Acute Hepatitis Is a Common Complication of Rabbit Antithymocyte Globulin (Thymoglobulin) Administered before Allogeneic Stem Cell Transplantation

Author

Médiavilla, Clémence, Vigouroux, Stéphane, Tabrizi, Reza, Pigneux, Arnaud, Duclos, Cédric, Mohr, Catherine, Robles, Margot, and Milpied, Noël

Abstract

Because antithymocyte globulin (ATG) is increasingly used to prevent graft-versus-host disease (GVHD), we performed a retrospective study in adult patients transplanted at our center between January 2008 and December 2012 to explore incidence, characteristics, potential risk factors, and consequences of severe acute hepatotoxicity (SAH) of rabbit ATG (Thymoglobulin) defined as a grade 3 to 4 increase of transaminases. Two hundred twelve patients were included. SAH was diagnosed in 55 patients, representing an incidence of 26%. SAH occurred at a median time of 2 days (range, 1 to 3) after ATG administration, reaching maximum median levels of aspartate aminotransferase and alanine aminotransferase of 8.7 × upper limit of normal (ULN; range, 1.2 to 160) and 11.7 × ULN (range, 4-100), respectively. The International Normalized Ratio was beyond the normal range in 44% of patients. Transaminases decreased below 2 × ULN after a median time of 9 days. We do not report any deleterious impact of SAH on survival, nonrelapse mortality, relapse, or GVHD. Blood systolic pressure < 90 mm Hg during administration of ATG and 2 previous autologous SCT were identified as risk factors for SAH. We believe physicians should be aware of this common toxicity immediately after the administration of ATG to avoid any potential hepatotoxic drug before the resolution and to prevent any risk of hemorrhagic accident.

Published
2024
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30. Correlation Between Histological Analysis and Clinical Features of Patients with Suspected Lower Gastro-Intestinal (GI) Graft Versus Host Disease (GVHD): Results of a Single Center Retrospective Study

Author

Breal, Claire, primary, Mohr, Catherine, additional, Sauvestre, Fanny, additional, Marty, Marion, additional, Goussot, Jean-francois, additional, Belleannee, Genevieve, additional, Tabrizi, Reza, additional, Vigouroux, Stephane, additional, and Milpied, Noel, additional

Published
2015
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32. In Brief

Author

Ponnusamy, Karthikeyan, Mohr, Catherine, and Curet, Myriam J.

Published
2011
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34. Prognostic Impact of Hematopoietic Recovery After Fludarabine, IV Busulfan and Antithymocyte Globulins (FB2 regimen) Reduced-Intensity Conditioning Regimen (RIC) Allogeneic Stem Cell Transplantation (allo-SCT)

Author

Lebourgeois, Amandine, primary, Loirat, Marion, additional, Tessoulin, Benoit, additional, Lestang, Elsa, additional, Peterlin, Pierre, additional, Malard, Florent, additional, Mohr, Catherine, additional, Touzeau, Cyrille, additional, Blin, Nicolas, additional, Clavert, Aline, additional, Augeul-Meunier, Karine, additional, Guillaume, Thierry, additional, Delaunay, Jacques, additional, Ayari, Sameh, additional, Brissot, Eolia, additional, Dubruille, Viviane, additional, Mahe, Beatrice, additional, Roland, Virginie, additional, Gastinne, Thomas, additional, Le Gouill, Steven, additional, Moreau, Philippe, additional, Mohty, Mohamad, additional, Planche, Lucie, additional, and Chevallier, Patrice, additional

Published
2012
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35. Comparison of PBSC Vs Cord Blood (CB) As Stem Cells Source for Reduced-Intensity Conditioning Regimen (RIC) Allogeneic Stem Cell Transplantation (allo-SCT) in Adult Patients with Haematological Diseases: A Single Centre Analysis.

Author

Lebourgeois, Amandine, primary, Loirat, Marion, additional, Tessoulin, Benoit, additional, Lestang, Elsa, additional, Peterlin, Pierre, additional, Malard, Florent, additional, Mohr, Catherine, additional, Touzeau, Cyrille, additional, Blin, Nicolas, additional, Clavert, Aline, additional, Augeul-Meunier, Karine, additional, Guillaume, Thierry, additional, Delaunay, Jacques, additional, Ayari, Sameh, additional, Brissot, Eolia, additional, Dubruille, Viviane, additional, Mahe, Beatrice, additional, Roland, Virginie, additional, Gastinne, Thomas, additional, Le Gouill, Steven, additional, Moreau, Philippe, additional, Mohty, Mohamad, additional, Planche, Lucie, additional, and Chevallier, Patrice, additional

Published
2012
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40. LETTERS.

Author

STREIT, CLARENCE K., HALE, R. E., MASSENGALE, ELIZABETH S., FLEISCHER, NAT, MOHR, CATHERINE A., BURNS, D., PEOPLES, JOHN D., BALLIN, LEONE C., CANER JR., GEORGE C., PIER, C. H., ABRAMS, HANNAH W., VESSELS, JACK, and MORSE, MARSTON

Subjects
ABUSE of military personnel
Published
1943

41. V1055: Robotic Nerve-Sparing Radical Prostatectomy using Potassium-Titanyl-Phosphate (KTP) Laser: Initial Experience in the Canine Model

Author

Gianduzzo, Troy R., primary, Colombo, Jose R., additional, Haber, Georges-Pascal, additional, Nahen, Kester, additional, Mohr, Catherine, additional, Magi-Galluzzi, Cristina, additional, Aron, Monish, additional, Hafron, Jason M., additional, Lin, Yi-Chia, additional, Santos, Bruno, additional, Gill, Inderbir S., additional, and Kaouk, Jihad H., additional

Published
2007
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43. Hypereosinophilia and Hypereosinophilic Syndromes: First Findings From a Nationwide Multicenter Cohort.

Author

Lefèvre, Guillaume, Bleuse, Séverine, Puyade, Mathieu, Moulis, Guillaume, Néel, Antoine, Abisror, Noémie, Baudet, Antoine, Bonnotte, Bernard, Dion, Jérémie, Dossier, Antoine, Grall, Maximilien, Lifermann, François, Limal, Nicolas, Lioger, Bertrand, Machelart, Irène, Mohr, Catherine, Outh, Roderau, Queyrel‐Moranne, Viviane, Slama, Borhane, and Tréfond, Ludovic

Subjects
*CHURG-Strauss syndrome, *HYPEREOSINOPHILIC syndrome, *IDIOPATHIC diseases, *WOMEN patients, *EOSINOPHILS
Abstract

ABSTRACT Background Methods Results Conclusions Trial Registration Hypereosinophilic syndromes (HES) are a heterogenous group of eosinophilic disorders. To date, only retrospective studies of limited sample‐size and/or follow‐up duration are available.The COHESion study is a national prospective multicenter multidisciplinary cohort recruiting both adults or children with the spectrum of eosinophilic disorders (including reactive HE/HES [HE/HES‐R], idiopathic HES [HES‐I], lymphocytic HES [HES‐L], neoplastic HE/HES [HE/HES‐N], HE of unknown significance [HE‐US], as well as IgG4‐related disease [IgG4RD] or ANCA‐negative eosinophilic granulomatosis with polyangiitis [EGPA] overlaps). Patients are followed‐up yearly. All data about final diagnosis, organ involvement assessments, and outcome profiles in HES‐I were captured and analyzed centrally by HES expert centers.From May 2019 to November 2023, 779 patients were included. For this preliminary analysis, 550 cases were available for centralized review (mean ± SD age: 56 ± 18 years, 42% of female patients). The final diagnoses were HES‐I (47%), HE/HES‐R (16%), HE‐US (15%), HE/HES‐N (7%), HE/HES‐L (6%), IgG4RD (2%), and ANCA‐negative EGPA (7%). In the 258 HES‐I patients, outcome profiles were classified as follows: 16.3% had a “single‐flare” without further relapse, 28.3% had a “relapsing–remitting” disease when there was at least a 6‐month period free of symptoms between two flares, 46.1% had a “persistent disease” requiring continuous treatment to avoid relapses (9.3% remained unclassified because of insufficient follow‐up).The COHESion cohort is the first nationwide prospective multicenter study collecting data on the full spectrum of HE/HES disorders. This preliminary analysis confirms that idiopathic HES patients have various outcome profiles, suggesting different underlying pathophysiological mechanisms and the need of patient‐specific management.ClinicalTrials.gov identifier: NCT 04018118 [ABSTRACT FROM AUTHOR]

Published
2025
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45. THE FUTURE OF THE FUTURE: FIVE BIG THINKERS PUZZLE OVER HOW GALLOPING ADVANCES IN GENE EDITING, A.I. AND MORE MIGHT (AND MIGHT NOT) TRANSFORM HUMANITY.

Author

BARZILAY, REGINA, CHURCH, GEORGE, EGAN, JENNIFER, MOHR, CATHERINE, and MUKHERJEE, SIDDHARTHA

Subjects
*GENOME editing, *GENE therapy, *ARTIFICIAL intelligence in medicine, *GENOMICS, *MEDICAL genomics
Abstract

The article presents a conversation of the advancement in gene editing and its impact on humans. Topics include the application of gene therapy in editing stem and sperm cells, the addition of missing genes in some gene therapies, the applications of artificial intelligence in medicine and the factors that will drive future advances of genomics.

Published
2018

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