Search

Your search keyword '"Ma, Yu-Ru"' showing total 23 results
Start Over Author "Ma, Yu-Ru"
23 results on '"Ma, Yu-Ru"'

6. Role of dynamic contrast-enhanced MRI in predicting severe acute radiation-induced rectal injury in patients with rectal cancer

Author

Chen, Yan, primary, Ding, Li, additional, Zhang, Zhi-wen, additional, Wu, Xue-han, additional, Que, Yu-tao, additional, Ma, Yu-ru, additional, Liu, Yi-yan, additional, Wen, Zi-qiang, additional, Yang, Xin-yue, additional, Lu, Bao-lan, additional, Bao, Yong, additional, Niu, Shao-qing, additional, and Yu, Shen-ping, additional

Published
2023
Full Text
View/download PDF

7. Problems and Countermeasures on Ethics of Non-medical Indicated Oocyte Freezing

Author

Ma Yu-ru, Tang Li, and Wang Hua-wei

Subjects
Control and Optimization, Applied Mathematics, Mechanical Engineering, General Engineering, Biomedical Engineering, Biophysics, Aerospace Engineering, General Physics and Astronomy, Ocean Engineering, Statistical and Nonlinear Physics, General Medicine, Computer Science Applications, Computational Mathematics, Mathematics (miscellaneous), Control and Systems Engineering, Electrical and Electronic Engineering, General Economics, Econometrics and Finance, Analysis, Mathematical Physics, Social Sciences (miscellaneous)
Published
2023

10. Response Letter to the Editor from Zhang et al: “Genetic Study in a Large Cohort Supported Different Pathogenesis of Graves’ Disease and Hashimoto’s Hypothyroidism”

Author

Zhang, Qian-Yue, primary, Liu, Wei, additional, Li, Lu, additional, Du, Wen-Hua, additional, Zuo, Chun-Lin, additional, Ye, Xiao-Ping, additional, Zhou, Zheng, additional, Yuan, Fei-Fei, additional, Ma, Yu-Ru, additional, Sun, Feng, additional, Yu, Sha-Sha, additional, Xie, Hui-Jun, additional, Zhang, Chang-Run, additional, Ying, Ying-Xia, additional, Yuan, Guo-Yue, additional, Gao, Guan-Qi, additional, Liang, Jun, additional, Zhao, Shuang-Xia, additional, and Song, Huai-Dong, additional

Published
2020
Full Text
View/download PDF

12. Genetic Study in a Large Cohort Supported Different Pathogenesis of Graves’ Disease and Hashimoto’s Hypothyroidism

Author

Zhang, Qian-Yue, primary, Liu, Wei, additional, Li, Lu, additional, Du, Wen-Hua, additional, Zuo, Chun-Lin, additional, Ye, Xiao-Ping, additional, Zhou, Zheng, additional, Yuan, Fei-Fei, additional, Ma, Yu-Ru, additional, Sun, Feng, additional, Yu, Sha-Sha, additional, Xie, Hui-Jun, additional, Zhang, Chang-Run, additional, Ying, Ying-Xia, additional, Yuan, Guo-Yue, additional, Gao, Guan-Qi, additional, Liang, Jun, additional, Zhao, Shuang-Xia, additional, and Song, Huai-Dong, additional

Published
2020
Full Text
View/download PDF

13. Could cytokine release syndrome induce acute myelofibrosis in CD19 chimeric antigen receptor T cells therapy?

Author

Lai, Xun, primary, Sun, Yun Yan, additional, Chang, Lung Ji, additional, Ma, Yu Ru, additional, Gu, Xue Zhong, additional, Yao, Xiang Mei, additional, Nie, Bo, additional, Wen, Yan, additional, Zhang, Xue Mei, additional, Jiang, Ya Xian, additional, Yang, Hui, additional, Yu, Li Qun, additional, Fang, Ming Jing, additional, Wang, Ling, additional, and Yuan Bo, Xue, additional

Published
2020
Full Text
View/download PDF

14. Compelling Evidence Linking CD40 Gene With Graves' Disease in the Chinese Han Population.

Author

Jiang, He, Yuan, Fei-Fei, Wang, Hai-Ning, Liu, Wei, Ye, Xiao-Ping, Yang, Shao-Ying, Xie, Hui-Jun, Yu, Sha-Sha, Ma, Yu-Ru, Zhang, Le-Le, Zhao, Shuang-Xia, and Song, Huai-Dong

Subjects
LOCUS (Genetics), CHINESE people, GENOME-wide association studies, SINGLE nucleotide polymorphisms, GENE expression, THYROID diseases
Abstract

Mutations in CD40 have been widely reported to be risk factors for Graves' disease (GD). The gene, along with its cognate ligand CD40L, may regulate pro-inflammatory and immune responses. Rs1883832, located at the -1 position of the Kozak sequence, is the most well-studied single nucleotide polymorphism (SNP) of CD40 , and has been confirmed to predispose those with the alteration to GD, regardless of ethnicity. Our genome-wide association study (GWAS) indicated that several SNPs, including rs1883832 located within the vicinity of CD40 were associated with GD in the Han Chinese population. Aiming at identifying the most consequential SNP and its underlying pathogenic mechanism, we performed a two-stage refined study on 8,171 patients with GD and 7,906 controls, and found rs1883832 was the most significantly GD-associated SNP in the CD40 gene region (P Combined = 9.17×10-11, OR = 1.18). Through searching the cis-expression quantitative trait locus database and using quantitative RT-PCR, we further discovered that the rs1883832 genotype can influence CD40 gene transcription. Furthermore, we demonstrated that rs1883832 is a susceptibility locus for pTRAb+ GD patients. In conclusion, the current study provides robust evidence that rs1883832 can regulate CD40 gene expression and affect serum TRAb levels, which ultimately contributes to the development of GD. [ABSTRACT FROM AUTHOR]

Published
2021
Full Text
View/download PDF

15. A Weighted Genetic Risk Score Using Known Susceptibility Variants to Predict Graves Disease Risk

Author

Ma, Yu-Ru, primary, Zhao, Shuang-Xia, additional, Li, Lu, additional, Sun, Feng, additional, Ye, Xiao-Ping, additional, Yuan, Fei-Fei, additional, Jiang, Dan, additional, Zhou, Zheng, additional, Zhang, Qian-Yue, additional, Wan, Yue-Yue, additional, Zhang, Guang-Ya, additional, Wu, Jing, additional, Zhang, Rui-Jia, additional, Fang, Ya, additional, and Song, Huai-Dong, additional

Published
2019
Full Text
View/download PDF

16. Effects of nuclear factor κB expression on retinal neovascularization and apoptosis in a diabetic retinopathy rat model

Author

Jiang, Ning, Chen, Xiao-Long, Yang, Hong-Wei, and Ma, Yu-Ru

Subjects
retinal neovascularization, diabetic retinopathy, Basic Research, cell apoptosis, lcsh:Ophthalmology, lcsh:RE1-994, nuclear factor κB
Abstract

AIM:To investigate the expression and role of nuclear factor κB (NF-κB) in diabetic retinopathy (DR) and its relationship with neovascularization and retinal cell apoptosis.METHODS: A total of 80 male Wistar rats were randomly assigned to control (4, 8, 12 and 16wk, n=10 in each group) and diabetes mellitus (DM) groups (4, 8, 12 and 16wk, n=10 in each group). A diabetic rat model was established by intraperitoneal injection of streptozotocin (60 mg/kg). After 4, 8, 12 and 16wk, rats were sacrificed. Retinal layers and retinal neovascularization growth were stained with hematoxylin-eosin and examined under light microscopy. Cell apoptosis in the retina was detected by TdT-mediated dUTP nick end labeling, and NF-κB distribution and expression in the retina was determined using immunohistochemistry.RESULTS: DM model success rate up to 100%. Diabetes model at each time point after the experimental groupcompared with the control group, the blood glucose was significantly increased, decreased body weight, each time point showed significant differences compared with the control group (PCONCLUSION:With the prolonging of DM progression, the expression NF-κB increases. NF-κB may be related to retinal cell apoptosis and neovascularization.

Published
2015

18. The genetic characteristics of congenital hypothyroidism in China by comprehensive screening of 21 candidate genes

Author

Sun, Feng, primary, Zhang, Jun-Xiu, additional, Yang, Chang-Yi, additional, Gao, Guan-Qi, additional, Zhu, Wen-Bin, additional, Han, Bing, additional, Zhang, Le-Le, additional, Wan, Yue-Yue, additional, Ye, Xiao-Ping, additional, Ma, Yu-Ru, additional, Zhang, Man-Man, additional, Yang, Liu, additional, Zhang, Qian-Yue, additional, Liu, Wei, additional, Guo, Cui-Cui, additional, Chen, Gang, additional, Zhao, Shuang-Xia, additional, Song, Ke-Yi, additional, and Song, Huai-Dong, additional

Published
2018
Full Text
View/download PDF

20. A dense mapping study of six European AITD susceptibility regions in a large Chinese Han Cohort of Graves' disease.

Author

Liu, Wei, Zhang, Qian‐Yue, Yuan, Fei‐Fei, Wang, Hai‐Ning, Zhang, Le‐Le, Ma, Yu‐Ru, Ye, Xiao‐Ping, Zhang, Man‐Man, Song, Zhi‐Yi, Li, Sheng‐Xian, Du, Wen‐Hua, Liang, Jun, Zhang, Xiao‐Mei, Gao, Guan‐Qi, Zhao, Shuang‐Xia, Chen, Feng‐ling, and Song, Huai‐Dong

Subjects
DISEASE susceptibility, GRAVES' disease, LOCUS (Genetics), CHINESE people, SINGLE nucleotide polymorphisms
Abstract

Summary: Objective: We aimed to investigate the six susceptibility loci of GD identified from European population in Chinese Han population and further to estimate the genetic heterogeneity of them in stratification of our GD patients. Design: Dense mapping studies based on GWAS. Patients: A total of 1536 GD patients and 1516 controls in GWAS stage and 1994 GD patients and 2085 controls and 5033 GD patients and 5389 controls in two replication stages. Measurements: Based on our previous GWAS data, independently GD‐associated SNPs in each region were identified by TagSNP analysis and logistic regression analysis. The association of these SNPs was investigated in 1994 GD patients and 2085 controls, and then, the significantly associated SNPs (P < 0.05) were further genotyped in a second cohort including 5033 GD patients and 5389 controls. Results: After the first replication stage, four SNPs from three regions with Pfirst < 0.05 were further selected and genotyped in another independent cohort. The association of two SNPs with GD was confirmed in combined Chinese cohorts: rs12575636 at 11q21 (Pcombined = 7.55 × 10−11, OR = 1.27) and rs1881145 in TRIB2 at 2p25.1 (Pcombined = 5.59 × 10−8, OR = 1.14). Further study disclosed no significant difference for these SNPs between GD subsets. However, eQTL data revealed that SESN3 could be a potential susceptibility gene of GD in 11q21 region. Conclusions: Out of the six susceptibility loci of GD identified from European population, two risk loci were confirmed in a large Chinese Han population. There is variability in GD genetic susceptibility in different ethnic groups. SESN3 is a potential susceptible gene of GD in 11q21. [ABSTRACT FROM AUTHOR]

Published
2018
Full Text
View/download PDF

23. Cover Image, Volume 89, Issue 6.

Author

Liu, Wei, Zhang, Qian‐Yue, Yuan, Fei‐Fei, Wang, Hai‐Ning, Zhang, Le‐Le, Ma, Yu‐Ru, Ye, Xiao‐Ping, Zhang, Man‐Man, Song, Zhi‐Yi, Li, Sheng‐Xian, Du, Wen‐Hua, Liang, Jun, Zhang, Xiao‐Mei, Gao, Guan‐Qi, Zhao, Shuang‐Xia, Chen, Feng‐ling, and Song, Huai‐Dong

Subjects
DISEASE susceptibility, CHINESE people, GRAVES' disease
Abstract

The cover image is based on the Original Article A dense mapping study of six European AITD susceptibility regions in a large Chinese Han Cohort of Graves' disease by Wei Liu et al., DOI: 10.1111/cen.13847. Design Credit: Qianyue Zhang. [ABSTRACT FROM AUTHOR]

Published
2018
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results