299 results on '"MacGregor, James T."'
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2. Folate Deficiency Causes Uracil Misincorporation into Human DNA and Chromosome Breakage: Implications for Cancer and Neuronal Damage
3. In vivo pig‐a and micronucleus study of the prototypical aneugen vinblastine sulfate
4. Toxicology and Genetic Toxicology in the New Era of 'Toxicogenomics': Impact of '-omics' Technologies
5. Strategies in case of positive in vivo results in genotoxicity testing
6. A review of mammalian in vivo genotoxicity of hexavalent chromium: implications for oral carcinogenicity risk assessment
7. Mouse Pig-a and Micronucleus Assays Respond to N-Ethyl-N-Nitrosourea, Benzo[a]Pyrene, and Ethyl Carbamate, but Not Pyrene or Methyl Carbamate
8. Comparison of male versus female responses in the Pig-a mutation assay
9. Rat Pig-a mutation assay responds to the genotoxic carcinogen ethyl carbamate but not the non-genotoxic carcinogen methyl carbamate
10. Human erythrocyte PIG-A assay: An easily monitored index of gene mutation requiring low volume blood samples
11. Cytogenetic Damage Induced by Folate Deficiency in Mice is Enhanced by Caffeine
12. Persistence of Cisplatin-Induced Mutagenicity in Hematopoietic Stem Cells: Implications for Secondary Cancer Risk Following Chemotherapy
13. Diethylnitrosamine genotoxicity evaluated in sprague dawley rats using Pig-a mutation and reticulocyte micronucleus assays
14. Pig-a gene mutation and micronucleated reticulocyte induction in rats exposed to tumorigenic doses of the leukemogenic agents chlorambucil, thiotepa, melphalan, and 1,3-propane sultone
15. Bruce Nathan Ames - Paradigm shifts inside the cancer research revolution
16. In vivo erythrocyte micronucleus assay : III. Validation and regulatory acceptance of automated scoring and the use of rat peripheral blood reticulocytes, with discussion of non-hematopoietic target cells and a single dose-level limit test
17. Flow cytometric analysis of Pig-a gene mutation and chromosomal damage induced by procarbazine hydrochloride in CD-1 mice
18. Building on the past, shaping the future: The environmental mutagenesis and genomics society
19. Efficient Monitoring of In Vivo Pig-a Gene Mutation and Chromosomal Damage: Summary of 7 Published Studies and Results From 11 New Reference Compounds
20. In Vivo Flow Cytometric Pig-a And Micronucleus Assays: Highly Sensitive Discrimination of the Carcinogen/Noncarcinogen Pair Benzo(a)Pyrene and Pyrene Using Acute and Repeated-Dose Designs
21. Interlaboratory Pig-a gene mutation assay trial: Studies of 1,3-propane sultone with immunomagnetic enrichment of mutant erythrocytes
22. International Pig-a gene mutation assay trial: Evaluation of transferability across 14 laboratories
23. Micronucleus assays in rodent tissues other than bone marrow
24. Flow cytometric scoring of micronucleated erythrocytes: an efficient platform for assessing in vivo cytogenetic damage
25. Reflections on the development of micronucleus assays
26. Assessment of systemic genetic damage in pediatric inflammatory bowel disease
27. Human bloodPIG‐Amutation and micronucleated reticulocyte flow cytometric assays: Method optimization and evaluation of intra‐ and inter‐subject variation
28. Integration of Mutation and Chromosomal Damage Endpoints into 28-Day Repeat Dose Toxicology Studies
29. Pig-a Mutation: Kinetics in Rat Erythrocytes Following Exposure to Five Prototypical Mutagens
30. Flow Cytometric Analysis of Micronuclei in Peripheral Blood Reticulocytes IV: An Index of Chromosomal Damage in the Rhesus Monkey (Macaca mulatta)
31. Flow Cytometric Analysis of Micronuclei in Peripheral Blood Reticulocytes III. An Efficient Method of Monitoring Chromosomal Damage in the Beagle Dog
32. Flow Cytometric Analysis of Micronuclei in Peripheral Blood Reticulocytes: I. Intra- and Interlaboratory Comparison with Microscopic Scoring
33. Flow Cytometric Analysis of Micronuclei in Peripheral Blood Reticulocytes: II. An Efficient Method of Monitoring Chromosomal Damage in the Rat
34. Biomarkers of Cancer Risk and Therapeutic Benefit: New Technologies, New Opportunities, and Some Challenges
35. The Future of Regulatory Toxicology: Impact of the Biotechnology Revolution
36. SNPs and Chips: Genomic Data in Safety Evaluation and Risk Assessment
37. In Vitro Human Tissue Models in Risk Assessment: Report of a Consensus-Building Workshop
38. 3Rs friendly study designs facilitate rat liver and blood micronucleus assays andPig‐agene mutation assessments: Proof‐of‐concept with 13 reference chemicals
39. Toxicology and genetic toxicology in the new era of “toxicogenomics”: impact of “-omics” technologies
40. Mutagen Formation in Wheat Gluten, Carbohydrates, and Amino Acid and Gluten Carbohydrate Blends
41. Human blood PIG‐A mutation and micronucleated reticulocyte flow cytometric assays: Method optimization and evaluation of intra‐ and inter‐subject variation.
42. Strategies and testing methods for identifying mutagenic risks
43. 3Rs friendly study designs facilitate rat liver and blood micronucleus assays and Pig‐a gene mutation assessments: Proof‐of‐concept with 13 reference chemicals.
44. Genetic and Carcinogenic Effects of Plant Flavonoids: An Overview
45. In vivo pig-a and micronucleus study of the prototypical aneugen vinblastine sulfate
46. Human Erythrocyte PIG-A Assay: An Easily Monitored Index of Gene Mutation Requiring Low Volume Blood Samples
47. <italic>In vivo pig‐a</italic> and micronucleus study of the prototypical aneugen vinblastine sulfate.
48. MousePig-aand micronucleus assays respond toN-ethyl-N-nitrosourea, benzo[a]pyrene, and ethyl carbamate, but not pyrene or methyl carbamate
49. IWGT report on quantitative approaches to genotoxicity risk assessment II. Use of point-of-departure (PoD) metrics in defining acceptable exposure limits and assessing human risk
50. IWGT report on quantitative approaches to genotoxicity risk assessment I. Methods and metrics for defining exposure–response relationships and points of departure (PoDs)
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