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2 results on '"Machlański T"'

1. [Antiviral effects of some biguanide derivatives].

Author

Denys A, Bialek J, and Machlański T

Subjects
Animals, Mice, Mice, Inbred BALB C, Antiviral Agents pharmacology, Biguanides pharmacology, Orthomyxoviridae drug effects, Parainfluenza Virus 1, Human drug effects
Published
1976

2. Relationships between chemical structure and antiviral activity of some biguanide derivatives.

Author

Denys A, Machlański T, Bialek J, and Mrozicki S

Subjects
Animals, Haplorhini, Hydrogen-Ion Concentration, Mice, Structure-Activity Relationship, Virus Cultivation, Biguanides pharmacology, Orthomyxoviridae drug effects, Parainfluenza Virus 1, Human drug effects
Abstract

The aim of this report was to indicate the correlation between chemical structure and antiviral activity of some biguanide derivatives obtained according to Monsanto Chemicals Ltd. Neth. Appl. 289. 283. The studies were carried out on the culture of monkey kidney cells infected with parainfluenza Sendai virus and on the mice infected with influenza virus. The increase of antiviral activities of N-Phenylbiguanide and N-p-Ethoxyphenylbiguanide was estimated.

Published
1977

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