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253 results on '"Madrid, Lola"'

1. Twice-Daily Dosing of Dolutegravir in Infants on Rifampicin Treatment: A Pharmacokinetic Substudy of the EMPIRICAL Trial.

Author

Jacobs, Tom, Mumbiro, Vivian, Cassia, Uneisse, Zimba, Kevin, Nalwanga, Damalie, Ballesteros, Alvaro, Domínguez-Rodríguez, Sara, Tagarro, Alfredo, Madrid, Lola, Mutata, Constantine, Chitsamatanga, Moses, Bwakura-Dangarembizi, Mutsa, Passanduca, Alfeu, Buck, W, Nduna, Bwendo, Chabala, Chishala, Najjingo, Elizabeth, Musiime, Victor, Moraleda, Cinta, Colbers, Angela, Mujuru, Hilda, Rojo, Pablo, and Burger, David

Subjects
HIV, dolutegravir, drug–drug interaction, infants, rifampicin, Female, Humans, Infant, Male, Heterocyclic Compounds, 3-Ring, HIV, HIV Infections, Oxazines, Piperazines, Pyridones, Rifampin
Abstract

BACKGROUND: We evaluated dolutegravir pharmacokinetics in infants with human immunodeficiency virus (HIV) receiving dolutegravir twice daily (BID) with rifampicin-based tuberculosis (TB) treatment compared with once daily (OD) without rifampicin. METHODS: Infants with HIV aged 1-12 months, weighing ≥3 kg, and receiving dolutegravir BID with rifampicin or OD without rifampicin were eligible. Six blood samples were taken over 12 (BID) or 24 hours (OD). Dolutegravir pharmacokinetic parameters, HIV viral load (VL) data, and adverse events (AEs) were reported. RESULTS: Twenty-seven of 30 enrolled infants had evaluable pharmacokinetic curves. The median (interquartile range) age was 7.1 months (6.1-9.9), weight was 6.3 kg (5.6-7.2), 21 (78%) received rifampicin, and 11 (41%) were female. Geometric mean ratios comparing dolutegravir BID with rifampicin versus OD without rifampicin were area under curve (AUC)0-24h 0.91 (95% confidence interval, .59-1.42), Ctrough 0.95 (0.57-1.59), Cmax 0.87 (0.57-1.33). One infant (5%) receiving rifampicin versus none without rifampicin had dolutegravir Ctrough

Published
2024

2. Child mortality in Eastern Ethiopia: acceptability of Postmortem minimally invasive tissue sampling in a predominantly muslim community

Author

Degefa, Ketema, Aliyi, Mohammad, Ackley, Caroline, Damise, Berhanu, Wakwaya, Getahun, Madrid, Lola, Assefa, Nega, Seale, Anna, Tadesse, Adugna, Sintayehu, Bizunesh, Zegeye, Yosef, Girma, Zerihun, Asfaw, Yenenesh Tilahun, Feyissa, Gurmu, Yigzaw, Hiwot, Taye, Eyoel, Asnake, Kidist, Tadesse, Simegn, Alemu, Addisu, Sarkodie-Mensah, Nana, Kone, Ahoua, Maixenchs, Maria, Blevins, John, and Breines, Markus

Published
2024
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3. Building bridges: enhancing cultural understanding and community engagement in the CHAMPS program—experience sought from Gobe Challa Village, Ethiopia

Author

Leulseged, Haleluya, Abdi, Faisel, Mohamed, Abdella, Wakoya, Getahun, Aliyi, Mohamed, Tesfaye, Adane, Yali, Segni, Mohamed, Khalifa, Mohamed, Akile, Yilma, Eden, Saboka, Mulualem, Bifle, Maji, Serkalem, Hussein, Obsitu, Aklilu, Freedom, Eshetu, Hawi, Tafa, Mestu, Ahmed, Obsa, Abdo, Mohamed, Madrid, Lola, and Assefa, Nega

Published
2024
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5. First-Line Antituberculosis Drug Concentrations in Infants With HIV and a History of Recent Admission With Severe Pneumonia.

Author

Chabala, Chishala, Jacobs, Tom, Moraleda, Cinta, Ndaferankhande, John, Mumbiro, Vivian, Passanduca, Alfeu, Namuziya, Natasha, Nalwanga, Damalie, Musiime, Victor, Ballesteros, Alvaro, Domínguez-Rodríguez, Sara, Chitsamatanga, Moses, Cassia, Uneisse, Nduna, Bwendo, Bramugy, Justina, Sacarlal, Jahit, Madrid, Lola, Nathoo, Kusum, Colbers, Angela, Burger, David, Mulenga, Veronica, Buck, William, Mujuru, Hilda, Te Brake, Lindsey, Rojo, Pablo, Tagarro, Alfredo, and Aarnoutse, Rob

Subjects
HIV, HRZE, Tuberculosis, infants, pharmacokinetics, Adult, Infant, Humans, Antitubercular Agents, HIV Infections, Pneumonia, Reference Values
Abstract

Optimal antituberculosis therapy is essential for favorable clinical outcomes. Peak plasma concentrations of first-line antituberculosis drugs in infants with living HIV receiving WHO-recommended dosing were low compared with reference values for adults, supporting studies on increased doses of first-line TB drugs in infants.

Published
2023

6. Brief Report: Suboptimal Lopinavir Exposure in Infants on Rifampicin Treatment Receiving Double-dosed or Semisuperboosted Lopinavir/Ritonavir: Time for a Change

Author

Jacobs, Tom G, Mumbiro, Vivian, Chitsamatanga, Moses, Namuziya, Natasha, Passanduca, Alfeu, Domínguez-Rodríguez, Sara, Tagarro, Alfredo, Nathoo, Kusum J, Nduna, Bwendo, Ballesteros, Alvaro, Madrid, Lola, Mujuru, Hilda A, Chabala, Chishala, Buck, W Chris, Rojo, Pablo, Burger, David M, Moraleda, Cinta, and Colbers, Angela

Subjects
Biomedical and Clinical Sciences, Clinical Sciences, Pediatric, HIV/AIDS, Infectious Diseases, Clinical Research, Clinical Trials and Supportive Activities, Pediatric AIDS, Evaluation of treatments and therapeutic interventions, 6.1 Pharmaceuticals, Infection, Good Health and Well Being, Male, Infant, Humans, Child, Female, Lopinavir, Ritonavir, Rifampin, HIV Infections, Anti-HIV Agents, HIV Protease Inhibitors, lopinavir, infants, rifampin, HIV, tuberculosis, drug-drug interaction, EMPIRICAL Clinical Trial Group, Public Health and Health Services, Virology, Clinical sciences, Epidemiology, Public health
Abstract

BackgroundAlthough super-boosted lopinavir/ritonavir (LPV/r; ratio 4:4 instead of 4:1) is recommended for infants living with HIV and receiving concomitant rifampicin, in clinical practice, many different LPV/r dosing strategies are applied due to poor availability of pediatric separate ritonavir formulations needed to superboost. We evaluated LPV pharmacokinetics in infants with HIV receiving LPV/r dosed according to local guidelines in various sub-Saharan African countries with or without rifampicin-based tuberculosis (TB) treatment.MethodsThis was a 2-arm pharmacokinetic substudy nested within the EMPIRICAL trial (#NCT03915366). Infants aged 1-12 months recruited into the main study were administered LPV/r according to local guidelines and drug availability either with or without rifampicin-based TB treatment; during rifampicin cotreatment, they received double-dosed (ratio 8:2) or semisuperboosted LPV/r (adding a ritonavir 100 mg crushed tablet to the evening LPV/r dose). Six blood samples were taken over 12 hours after intake of LPV/r.ResultsIn total, 14/16 included infants had evaluable pharmacokinetic curves; 9/14 had rifampicin cotreatment (5 received double-dosed and 4 semisuperboosted LPV/r). The median (IQR) age was 6.4 months (5.4-9.8), weight 6.0 kg (5.2-6.8), and 10/14 were male. Of those receiving rifampicin, 6/9 infants (67%) had LPV Ctrough

Published
2023

7. Etiologies and comorbidities of meningitis deaths in children under 5 years in high-mortality settings: Insights from the CHAMPS Network in the post-pneumococcal vaccine era

Author

Mahtab, Sana, Madewell, Zachary J., Baillie, Vicky, Dangor, Ziyaad, Lala, Sanjay G., Assefa, Nega, Berihun, Mulu, Madrid, Lola, Regassa, Lemma Demissie, Scott, J. Anthony G., Ameh, Soter, Bangura, Joseph S., Ita, Okokon, Kaluma, Erick, Ogbuanu, Ikechukwu Udo, Gaume, Brigitte, Kotloff, Karen L., Sow, Samba O., Tapia, Milagritos D., Ajanovic, Sara, Garrine, Marcelino, Mandomando, Inacio, Varo, Rosauro, Xerinda, Elisio G., Alam, Muntasir, El Arifeen, Shams, Gurley, Emily S., Hossain, Mohammad Zahid, Rahman, Afruna, Akelo, Victor, Igunza, Kitiezo Aggrey, Onyango, Clayton, Onyango, Dickens, Verani, Jennifer R., Mutevedzi, Portia, Whitney, Cynthia G., Blau, Dianna M., Madhi, Shabir A., and Bassat, Quique

Published
2024
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8. Post-mortem investigation of deaths due to pneumonia in children aged 1–59 months in sub-Saharan Africa and South Asia from 2016 to 2022: an observational study

Author

Adam, Yasmin, Agaya, Janet, Ahmed, A.S.M. Nawshad Uddin, Ahmed, Dilruba, Alemu, Addisu, Ali, Solomon, Ameh, Soter, Aol, George, Argeseanu, Solveig, Ariuman, Farida, Balogun, Oluseyi, Bari, Sanwarul, Basket, Margaret, Begum, Ferdousi, Bhandari, Manu, Blevins, John, Bunn, James, Bursuc, Courtney, Cain, Carrie Jo, Chawana, Richard, Chawla, Kiranpreet, Chukwuegbo, Cornell, Diarra, Kounandji, Diarra, Tiéman, Diaz, Maureen, Duduyemi, Babatunde, Fairchild, Karen D., Flora, Meerjady Sabrina, Fritz, Ashleigh, Garel, Mischka, Gaume, Brigitte, Gizaw, Mahlet Abayneh, Govender, Nelesh P., Greene, Carol L., Gure, Tadesse, Halu, Binyam, Hoque, Mahbubul, Hwinya, Cleopas, Ibrahim, Alexander M., Igunza, Kitiezo Aggrey, Islam, Ferdousi, Ita, Okokon, Jambai, Amara, Johnson, J. Kristie, Juma, Jane, Kaluma, Erick, Kamal, Mohammed, Kaykay, Osman, Kenneh, Sartie, Khagayi, Sammy, Koka, Rima, Kone, Diakaridia, Koplan, Jeffrey P., Kourouma, Nana, Kowuor, Dickens, LaHatte, Kristin, Lala, Sanjay G., Lee, Kyu Han, Liu, Lucy, Lombaard, Hennie, Maixenchs, Maria, Manhique, Zara, Mannah, Margaret, Martines, Roosecelis, Mash, Ronald, Mehta, Ashka, Menéndez, Clara, Misore, Thomas, Mocumbi, Sibone, Moseray, Andrew, Moses, Francis, Muga, Christopher, Munguambe, Khátia, Myburgh, Nellie, Nair, Shailesh, Ndagurwa, Pedzisai, Nhacolo, Ariel, Nhampossa, Tacilta, Nwajiobi, Princewill, Ochola, Christine, Oliech, Richard, Oluoch, Bernard, Onwuchekwa, Uma U., Onyango, Peter Nyamthimba, Orlien, Stian MS, Otieno, Peter, Oundo, Joseph, Owuor, Harun, Parveen, Shahana, Petersen, Karen, Pratt, Samuel, Rahman, Mahbubur, Rahman, Mohammad Mosiur, Rahman, Mustafizur, Raymer, Sarah, Ritter, Jana, Salzberg, Navit T., Samura, Solomon, Sannoh, Sulaiman, Sanogo, Doh, Seppeh, Martin, Sesay, Tom, Sesay, Joseph Kamanda, Shirin, Tahmina, Sissoko, Seydou, Smart, Francis, Sorour, Gillian, Squire, James, Swaray-Deen, Alim, Swart, Peter J., Tarawally, Fatmata Bintu, Tasnim, Saria, Temesgen, Fikremelekot, Tennant, Sharon M., Traore, Cheick Bougadari, Traore, Awa, Velaphi, Sithembiso, Vyas, Kurt, Wadhwa, Ashutosh, Wadula, Jeannette, Waller, Jessica, Wanga, Valentine, Warang, Shamta, Were, Joyce Akinyi, Wilson, Tais, Winchell, Jonas, Wise, Amy, Witherbee, Jakob, Yeshi, Melisachew Mulatu, Zaman, K., Mahtab, Sana, Blau, Dianna M, Madewell, Zachary J, Ogbuanu, Ikechukwu, Ojulong, Julius, Lako, Sandra, Legesse, Hailemariam, Bangura, Joseph S, Bassat, Quique, Mandomando, Inacio, Xerinda, Elisio, Fernandes, Fabiola, Varo, Rosauro, Sow, Samba O, Kotloff, Karen L, Tapia, Milagritos D, Keita, Adama Mamby, Sidibe, Diakaridia, Onyango, Dickens, Akelo, Victor, Gethi, Dickson, Verani, Jennifer R, Revathi, Gunturu, Scott, J Anthony G, Assefa, Nega, Madrid, Lola, Bizuayehu, Hiwot, Tirfe, Tseyon Tesfaye, El Arifeen, Shams, Gurley, Emily S, Islam, Kazi Munisul, Alam, Muntasir, Zahid Hossain, Mohammad, Dangor, Ziyaad, Baillie, Vicky L, Hale, Martin, Mutevedzi, Portia, Breiman, Robert F, Whitney, Cynthia G, and Madhi, Shabir A

Published
2024
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9. Burden of child mortality from malaria in high endemic areas: Results from the CHAMPS network using minimally invasive tissue sampling

Author

Ogbuanu, Ikechukwu U., Otieno, Kephas, Varo, Rosauro, Sow, Samba O., Ojulong, Julius, Duduyemi, Babatunde, Kowuor, Dickens, Cain, Carrie Jo, Rogena, Emily A., Onyango, Dickens, Akelo, Victor, Tippett Barr, Beth A., terKuile, Feiko, Kotloff, Karen L., Tapia, Milagritos D., Keita, Adama Mamby, Juma, Jane, Assefa, Nega, Assegid, Nardos, Acham, Yenework, Madrid, Lola, Scott, J. Anthony G., Arifeen, Shams El, Gurley, Emily S., Mahtab, Sana, Dangor, Ziyaad, Wadula, Jeannette, Dutoit, Jeanie, Madhi, Shabir A., Mandomando, Inácio, Torres-Fernandez, David, Kincardett, Milton, Mabunda, Rita, Mutevedzi, Portia, Madewell, Zachary J., Blau, Dianna M., Whitney, Cynthia G., Samuels, Aaron M., and Bassat, Quique

Published
2024
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10. Child deaths caused by Klebsiella pneumoniae in sub-Saharan Africa and south Asia: a secondary analysis of Child Health and Mortality Prevention Surveillance (CHAMPS) data

Author

Verani, Jennifer R, Blau, Dianna M, Gurley, Emily S, Akelo, Victor, Assefa, Nega, Baillie, Vicky, Bassat, Quique, Berhane, Mussie, Bunn, James, Cossa, Anelsio C A, El Arifeen, Shams, Gunturu, Revathi, Hale, Martin, Igunza, Aggrey, Keita, Adama M, Kenneh, Sartie, Kotloff, Karen L, Kowuor, Dickens, Mabunda, Rita, Madewell, Zachary J, Madhi, Shabir, Madrid, Lola, Mahtab, Sana, Miguel, Judice, Murila, Florence V, Ogbuanu, Ikechukwu U, Ojulong, Julius, Onyango, Dickens, Oundo, Joe O, Scott, J Anthony G, Sow, Samba, Tapia, Milagritos, Traore, Cheick B, Velaphi, Sithembiso, Whitney, Cynthia G, Mandomando, Inacio, and Breiman, Robert F

Published
2024
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11. Mortality associated with third-generation cephalosporin resistance in Enterobacterales bloodstream infections at eight sub-Saharan African hospitals (MBIRA): a prospective cohort study

Author

Aliye, Jabir, Assefa, Nega, Edessa, Dumessa, Oundo, Joseph, Berihun, Mulu, Dankwah, Thomas, Osei, Mary M, Fandoh, Maud, Gakpo, Margaret, Mulunda, Caroline, Mvera, Benedict, Chimenya, Mabvuto, Feasey, Nicholas, Mallewa, Jane, Abdulraheem, Khadija, Akujobi, Tobechi A, Okonkwo, Chinelo H, Britz, Luzell, Bulbula, André N H, Fataar, Aaqilah, Mmbaga, Blandina T, Ng'unda, Neema, Chirwa, Uchizi, Kakula, Nyambe, Mutemba, Charles, Nakazwe, Ruth, Aiken, Alexander M, Rehman, Andrea M, de Kraker, Marlieke E A, Madrid, Lola, Kebede, Meron, Labi, Appiah-Korang, Obeng-Nkrumah, Noah, Nyamwaya, Brian, Kagucia, Eunice, Cocker, Derek, Kawaza, Kondwani, Lester, Rebecca, Iregbu, Kenneth C, Medugu, Nubwa, Nwajiobi-Princewill, Philip I, Dramowski, Angela, Sonda, Tolbert, Hemed, Asia, Fwoloshi, Sombo, Ojok, David, Scott, J Anthony G, and Whitelaw, Andrew

Published
2023
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12. Provider adherence to clinical care recommendations for infants and children who died in seven low- and middle-income countries in the Child Health and Mortality Prevention Surveillance (CHAMPS) network

Author

Solomon, Fatima, Sorour, Gillian, Lombaard, Hennie, Wadula, Jeannette, Petersen, Karen, Hale, Martin, Govender, Nelesh P., Swart, Peter J., Lala, Sanjay G., Velaphi, Sithembiso, Chawana, Richard, Adam, Yasmin, Wise, Amy, Fritz, Ashleigh, Myburgh, Nellie, Ndagurwa, Pedzisai, Hwinya, Cleopas, Bari, Sanwarul, Parveen, Shahana, Kamal, Mohammed, Uddin Ahmed, A.S.M. Nawshad, Hoque, Mahbubul, Tasnim, Saria, Islam, Ferdousi, Ariuman, Farida, Rahman, Mohammad Mosiur, Begum, Ferdousi, Zaman, K., Rahman, Mustafizur, Ahmed, Dilruba, Flora, Meerjady Sabrina, Shirin, Tahmina, Rahman, Mahbubur, Oundo, Joseph, Ibrahim, Alexander M., Temesgen, Fikremelekot, Gure, Tadesse, Alemu, Addisu, Yeshi, Melisachew Mulatu, Gizaw, Mahlet Abayneh, Orlien, Stian, Ali, Solomon, Otieno, Peter, Onyango, Peter Nyamthimba, Agaya, Janet, Oliech, Richard, Were, Joyce Akinyi, Gethi, Dickson, Khagayi, Sammy, Aol, George, Misore, Thomas, Owuor, Harun, Mugah, Christopher, Oluoch, Bernard, Ochola, Christine, Tennant, Sharon M., Greene, Carol L., Mehta, Ashka, Johnson, J. Kristie, Gaume, Brigitte, Koka, Rima, Fairchild, Karen D., Kone, Diakaridia, Sanogo, Doh, Onwuchekwa, Uma U., Kourouma, Nana, Sissoko, Seydou, Traore, Cheick Bougadari, Juma, Jane, Diarra, Kounandji, Traore, Awa, Diarra, Tiéman, Chawla, Kiranpreet, Nhampossa, Tacilta, Manhique, Zara, Mocumbi, Sibone, Menéndez, Clara, Munguambe, Khátia, Nhacolo, Ariel, Maixenchs, Maria, Moseray, Andrew, Tarawally, Fatmata Bintu, Seppeh, Martin, Mash, Ronald, Ojulong, Julius, Duduyemi, Babatunde, Bunn, James, Swaray-Deen, Alim, Bangura, Joseph, Jambai, Amara, Mannah, Margaret, Ita, Okokon, Chukwuegbo, Cornell, Sannoh, Sulaiman, Nwajiobi, Princewill, Kowuor, Dickens, Kaluma, Erick, Balogun, Oluseyi, Samura, Solomon, Pratt, Samuel, Moses, Francis, Sesay, Tom, Squire, James, Sesay, Joseph Kamanda, Kaykay, Osman, Halu, Binyam, Legesse, Hailemariam, Smart, Francis, Kenneh, Sartie, Ameh, Soter, Ritter, Jana, Wilson, Tais, Winchell, Jonas, Witherbee, Jakob, Salzberg, Navit T., Koplan, Jeffrey P., Basket, Margaret, Wadhwa, Ashutosh, Lee, Kyu Han, Wanga, Valentine, Martines, Roosecelis, Warang, Shamta, Diaz, Maureen, Waller, Jessica, Nair, Shailesh, Liu, Lucy, Bursuc, Courtney, LaHatte, Kristin, Raymer, Sarah, Blevins, John, Argeseanu, Solveig, Vyas, Kurt, Bhandari, Manu, Rees, Chris A., Igunza, Kitiezo Aggrey, Madewell, Zachary J., Akelo, Victor, Onyango, Dickens, El Arifeen, Shams, Gurley, Emily S., Hossain, Mohammad Zahid, Rahman, Afruna, Alam, Muntasir, Scott, J. Anthony G., Assefa, Nega, Madrid, Lola, Belachew, Anteneh, Leulseged, Haleluya, Kotloff, Karen L., Sow, Samba O., Tapia, Milagritos D., Keita, Adama Mamby, Sidibe, Diakaridia, Sitoe, Antonio, Varo, Rosauro, Ajanovic, Sara, Bassat, Quique, Mandomando, Inácio, Tippett Barr, Beth A., Ogbuanu, Ikechukwu, Cain, Carrie Jo, Bassey, Ima-Abasi, Luke, Ronita, Gassama, Khadija, Madhi, Shabir, Dangor, Ziyaad, Mahtab, Sana, du Toit, Jeanie, Mutevedzi, Portia C., Blau, Dianna M., Breiman, Robert F., and Whitney, Cynthia G.

Published
2023
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13. Causes of stillbirth and death among children younger than 5 years in eastern Hararghe, Ethiopia: a population-based post-mortem study

Author

Deresa, Merga, Mengesha, Gezahegn, Samuel, Tigistu, Taye, Eyoel, Aliyi, Mohammed, Feyissa, Gurmu, Tilahun, Yenenesh, Wakwaya, Getahun, Tadesse, Simegn, Asnake, Kidish, Ayalew, Mariamcher, Kidane, Azeb, Azore, Emmanuel, Berhanu, Mussie, Berihun, Mulu, Deresa, Mersan, Assegid, Nardos, Voller, Shirine, Mekonnen, Mahlet, Alemaheyu, Andualem, Sarkodie-Mensah, Nana, Morrison, Beth, Jibendi, Boniface, Worku, Asnake, Mirkuzie, Alemenesh, Getnet, Fentabil, Madrid, Lola, Alemu, Addisu, Seale, Anna C, Oundo, Joe, Tesfaye, Tseyon, Marami, Dadi, Yigzaw, Hiwot, Ibrahim, Alexander, Degefa, Ketema, Dufera, Tadesse, Teklemariam, Zelalem, Gure, Tadesse, Leulseged, Haleluya, Wittmann, Stefanie, Abayneh, Mahlet, Fentaw, Surafel, Temesgen, Fikremelekot, Yeshi, Melisachew M, Dubale, Mehret, Girma, Zerihun, Ackley, Caroline, Damisse, Berhanu, Breines, Markus, Orlien, Stian M S, Blau, Dianna M, Breiman, Robert F, Abate, Ebba, Dessie, Yadeta, Assefa, Nega, and Scott, J Anthony G

Published
2023
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14. Neural tube defects as a cause of death among stillbirths, infants, and children younger than 5 years in sub-Saharan Africa and southeast Asia: an analysis of the CHAMPS network

Author

Nawshad Uddin Ahmed, A.S.M., Hoque, Mahbubul, Kamal, Mohammed, Mosiur, Mohammad, Begum, Ferdousi, Tasnim, Saria, Flora, Meerjady Sabrina, Arjuman, Farida, Khan, Iqbal Ansary, Shirin, Tahmina, Rahman, Mahbubur, Bari, Sanwarul, Parveen, Shahana, Islam, Farzana, Hossain, Mohammad Zahid, Islam, Kazi Munisul, Ahmed, Mohammad Sabbir, Zaman, K, Rahman, Mustafizur, Ahmed, Dilruba, Chowdhury, Md Atique Iqbal, Alam, Muntasir, Lee, Kyu Han, Islam, Ferdousi, Oundo, Joseph O, Temesgen, Fikremelekot, Yeshi, Melisachew Mulatu, Ibrahim, Alexander M, Gure, Tadesse, Edris, Yunus, Alemu, Addisu, Marami, Dadi, Lemma, Ephrem, Mekonnen, Ayantu, Wale, Henok, Tesfaye, Tseyon, Leulseged, Haleluya, Dufera, Tadesse, Belachew, Anteneh, Getnet, Fentabil, Fentaw, Surafel, Acham, Yenework, Orlien, Stian MS, Abayneh Gizaw, Mahlet, Rogena, Emily, Murila, Florence, Revathi, Gunturu, Mitei, Paul K, Kuria, Magdalene, Verani, Jennifer R, Igunza, Aggrey, Nyamthimba, Peter, Oele, Elizabeth, Fairchild, Karen D, Greene, Carol L, Koka, Rima, Mehta, Ashka, Tennant, Sharon M, Johnson, J Kristie, Keita, Tatiana, Keita, Adama Mamby, Kourouma, Nana, Onwuchekwa, Uma U, Traore, Awa, Sanogo, Doh, Sidibe, Diakaridia, Sissoko, Seydou, Kone, Diakaridia, Kindcardett, Milton, Munguambe, Khátia, Nhacolo, Ariel, Nhampossa, Tacilta, Vitorino, Pio, Xerinda, Elisio, Bramugy, Justina, Monjane, Celso, Nhachungue, Sheila, Hurtado, Juan Carlos, Maixenchs, Maria, Menéndez, Clara, Ordi, Jaume, Rakislova, Natalia, Valente, Marta, Manhique, Zara, Chitungo, Dercio, Mocumbi, Sibone, Carrilho, Carla, Fernandes, Fabiola, Pass Philipsborn, Rebecca, Koplan, Jeffrey P, Garel, Mischka, Dewey, Betsy, Nair, Shailesh, Salzberg, Navit T, Liu, Lucy, Alkis-Ramirez, Rebecca, Ritter, Jana M, Zaki, Sherif R, Gary, Joy, Winchell, Jonas M, Witherbee, Jacob, Waller, Jessica L, Fayorsey, Ruby, Luke, Ronita, Bassey, Ima-Abasi, Kowuor, Dickens, Sesay, Foday, Kosia, Baindu, Pratt, Samuel, Cain, Carrie-Jo, Samura, Solomon, Solomon, Fatima, Fritz, Ashleigh, Dludlu, Noluthando, Ntuli, Constance, Chawana, Richard, Petersen, Karen, Lala, Sanjay G, Velaphi, Sithembiso, Wadula, Jeannette, Hale, Martin, Swart, Peter J, Lombaard, Hennie, Moosa, Rahima, Sorour, Gillian, Madrid, Lola, Vyas, Kartavya J, Kancherla, Vijaya, Suchdev, Parminder S, Bassat, Quique, Sow, Samba O, El Arifeen, Shams, Madhi, Shabir A, Onyango, Dickens, Ogbuanu, Ikechukwu, Scott, J Anthony G, Blau, Dianna, Mandomando, Inacio, Keita, Adama M, Gurley, Emily S, Mahtab, Sana, Akelo, Victor, Sannoh, Sulaiman, Tilahun, Yenenesh, Varo, Rosauro, Onwuchekwa, Uma, Rahman, Afruna, Adam, Yasmin, Omore, Richard, Lako, Sandra, Wise, Amy, Tippet-Barr, Beth A, Kaluma, Erick, Ajanovic, Sara, Kotloff, Karen L, Mutevedzi, Portia, Tapia, Milagritos D, Moses, Francis, Whitney, Cynthia G, and Assefa, Nega

Published
2023
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16. Building Bridges: Enhancing Cultural Understanding and Community Engagement in the CHAMPS Program – Experience sought from Gobe Challa Village, Ethiopia

Author

Leulseged, Haleluya, primary, Abdi, Faisel, additional, Mohamed, Abdella, additional, Wakoya, Getahun, additional, Aliyi, Mohamed, additional, Tesfaye, Adane, additional, Yali, Segni, additional, Mohamed, Khalifa, additional, Mohamed, Akile, additional, Yilma, Eden, additional, Saboka, Mulualem, additional, Bifle, Maji, additional, Workalemawu, Serkalem, additional, Hussein, Obsitu, additional, Aklilu, Freedom, additional, Eshetu, Hawi, additional, Tafa, Mestu, additional, Ahmed, Obsa, additional, Abdo, Mohamed, additional, Madrid, Lola, additional, and Assefa, Nega, additional

Published
2024
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17. Global burden of acute lower respiratory infection associated with human metapneumovirus in children under 5 years in 2018: a systematic review and modelling study

Author

Libster, Romina, Otieno, Grieven, Joundi, Imane, Broor, Shobha, Nicol, Mark, Amarchand, Ritvik, Shi, Ting, López-Labrador, F. Xavier, Baker, Julia M., Jamison, Alexandra, Choudekar, Avinash, Juvekar, Sanjay, Obermeier, Patrick, Schweiger, Brunhilde, Madrid, Lola, Thomas, Elizabeth, Lanaspa, Miguel, Nohynek, Hanna, Nokes, James, Werner, Marta, Danhg, Anh, Chadha, Mandeep, Puig-Barberà, Joan, Caballero, Mauricio T., Mathisen, Maria, Walaza, Sibongile, Hellferscee, Orienka, Laubscher, Matt, Higdon, Melissa M., Haddix, Meredith, Sawatwong, Pongpun, Baggett, Henry C., Seidenberg, Phil, Mwanayanda, Lawrence, Antonio, Martin, Ebruke, Bernard E., Adams, Tanja, Rahman, Mustafizur, Rahman, Mohammed Ziaur, Sow, Samboa O., Baillie, Vicky L., Workman, Lesley, Toizumi, Michiko, Tapia, Milagritos D., Nguyen, Thi hien anh, Morpeth, Susan, Wang, Xin, Li, You, Deloria-Knoll, Maria, Madhi, Shabir A, Cohen, Cheryl, Ali, Asad, Basnet, Sudha, Bassat, Quique, Brooks, W Abdullah, Chittaganpitch, Malinee, Echavarria, Marcela, Fasce, Rodrigo A, Goswami, Doli, Hirve, Siddhivinayak, Homaira, Nusrat, Howie, Stephen R C, Kotloff, Karen L, Khuri-Bulos, Najwa, Krishnan, Anand, Lucero, Marilla G, Lupisan, Socorro, Mira-Iglesias, Ainara, Moore, David P, Moraleda, Cinta, Nunes, Marta, Oshitani, Histoshi, Owor, Betty E, Polack, Fernando P, O'Brien, Katherine L, Rasmussen, Zeba A, Rath, Barbara A, Salimi, Vahid, Scott, J Anthony G, Simões, Eric A F, Strand, Tor A, Thea, Donald M, Treurnicht, Florette K, Vaccari, Linda C, Yoshida, Lay-Myint, Zar, Heather J, Campbell, Harry, and Nair, Harish

Published
2021
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18. Plasma MicroRNA Profiling of Plasmodium falciparum Biomass and Association with Severity of Malaria Disease

Author

Gupta, Himanshu, Rubio, Mercedes, Sitoe, Antonio, Varo, Rosauro, Cistero, Pau, Madrid, Lola, Cuamba, Inocencia, Jimenez, Alfons, Martianez-Vendrell, Xavier, Barrios, Diana, Pantano, Lorena, Brimacombe, Allison, Bustamante, Mariona, Bassa, Quique, and Mayor, Alfredo

Subjects
Gene expression -- Health aspects, Prognosis -- Genetic aspects, MicroRNA -- Health aspects, Malaria -- Genetic aspects -- Development and progression -- Care and treatment, Health
Abstract

Case-fatality rates for Plasmodium falciparum severe malaria (SM) remain unacceptably high in young children in Africa (1). Early detection and prompt treatment of SM are critical to improve the prognosis [...]

Published
2021
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20. Global burden of respiratory infections associated with seasonal influenza in children under 5 years in 2018: a systematic review and modelling study

Author

Nair, Harish, Campbell, Harry, Wang, Xin, Li, You, Chung, Alexandria, Rahi, Manveer, Abbas, Qalab, Ali, Asad, Bhutta, Zulfiqar A, Saeed, Bushra, Soofi, Sajid B, Yousafzai, Mohammad Tahir, Zaidi, Anita K, Amu, Alberta, Awini, Elizabeth, Azziz-Baumgartner, Eduardo, Baggett, Henry C, Chaves, Sandra S, Shang, Nong, Schrag, Stephanie J, Widdowson, Marc-Alain, Tempia, Stefano, Bassat, Quique, Lanaspa, Miguel, Acácio, Sozinho, Brooks, W Abdullah, Driscoll, Amanda, Knoll, Maria Deloria, O'Brien, Katherine L, Prosperi, Christine, Baqui, Abdullah H, Mullany, Luke, Byass, Peter, Cohen, Cheryl, von Gottberg, Anne, Hellferscee, Orienka, Treurnicht, Florette K, Walaza, Sibongile, Goswami, Doli, Rahman, Mustafizur, Connor, Nicholas E, El Arifeen, Shams, Echavarria, Marcela, Marcone, Débora N, Reyes, Noelia, Gutierrez, Andrea, Rodriguez, Ivan, Lopez, Olga, Ortiz, David, Gonzalez, Nathaly, Gentile, Angela, del Valle Juarez, Maria, Gordon, Aubree, Cutland, Clare, Groome, Michelle, Madhi, Shabir A, Nunes, Marta C, Nzenze, Susan, Heikkinen, Terho, Hirve, Siddhivinayak, Juvekar, Sanjay, Halasa, Natasha, Jara, Jorge H, Bernart, Chris, Katz, Mark A, Gofer, Ilan, Avni, Yonat Shemer, Khuri-Bulos, Najwa, Faori, Samir, Shehabi, Asem, Krishnan, Anand, Kumar, Rakesh, Amarchand, Ritvik, Contreras, Carmen L, de Leon, Oscar, Lopez, Maria R, McCracken, John P, Maldonado, Herberth, Samayoa, Antonio P, Gomez, Ana B, Lucero, Marilla G, Nillos, Leilani T, Lupisan, Socorro P, Nohynek, Hanna, Mira-Iglesias, Ainara, Puig-Barberà, Joan, Díez-Domingo, Javier, Gessner, Bradford D, Njanpop-Lafourcade, Berthe-Marie, Moïsi, Jennifer C, Tall, Haoua, Munywoki, Patrick K, Ngama, Mwanjuma, Nokes, D James, Omer, Saad B, Clark, Dayna R, Ourohiré, Millogo, Ali, Sié, Pascal, Zabré, Cheik, Bagagnan H, Caballero, Mauricio T, Libster, Romina, Polack, Fernando P, Rasmussen, Zeba A, Thomas, Elizabeth D, Baker, Julia M, Rath, Barbara A, Obermeier, Patrick E, Hassanuzzaman, MD., Islam, Maksuda, Islam, Mohammad S, Saha, Samir K, Panigrahi, Pinaki, Bose, Anuradha, Isaac, Rita, Murdoch, David, Nanda, Pritish, Qazi, Shamim A, Hessong, Danielle, Simőes, Eric AF, Sotomayor, Viviana, Thamthitiwat, Somsak, Chittaganpitch, Malinee, Dawood, Halima, Kyobutungi, Catherine, Wamukoya, Marylene, Ziraba, Abdhalah K, Yoshida, Lay-Myint, Yoshihara, Keisuke, Dand, Duc-Anh, Le, Minh-Nhat, Nicol, Mark P, Zar, Heather J, Broor, Shobha, Chadha, Mandeep, Madrid, Lola, Gresh, Lionel, Balmaseda, Angel, Kuan, Guillermina, Wairagkar, Niteen, Tapia, Milagritos D, Knobler, Stacey L, Barahona, Alfredo, Ferguson, Ericka, Schweiger, Brunhilde, Abdullah Brooks, W, Fasce, Rodrigo A, and Simões, Eric AF

Published
2020
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21. Comparison of causes of stillbirth and child deaths as determined by verbal autopsy and minimally invasive tissue sampling

Author

Assefa, Nega, primary, Scott, Anthony, additional, Madrid, Lola, additional, Dheresa, Merga, additional, Mengesha, Gezahegn, additional, Mahdi, Shabir, additional, Mahtab, Sana, additional, Dangor, Ziyaad, additional, Myburgh, Nellie, additional, Mothibi, Lesego Kamogelo, additional, Sow, Samba O., additional, Kotloff, Karen L., additional, Tapia, Milagritos D., additional, Onwuchekwa, Uma U., additional, Djiteye, Mahamane, additional, Varo, Rosauro, additional, Mandomando, Inacio, additional, Nhacolo, Ariel, additional, Sacoor, Charfudin, additional, Xerinda, Elisio, additional, Ogbuanu, Ikechukwu, additional, Samura, Solomon, additional, Duduyemi, Babatunde, additional, Swaray-Deen, Alim, additional, Bah, Abdulai, additional, Arifeen, Shams El, additional, Gurley, Emily S, additional, Hossain, Mohammed Zahid, additional, Rahman, Afruna, additional, Chowdhury, Atique Iqbal, additional, Quique, Bassat, additional, Mutevedzi, Portia, additional, Solveig, Argeseanu, additional, Blau, Dianna, additional, and Whitney, Cyndy, additional

Published
2024
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22. Post-mortem investigation of deaths due to pneumonia in children aged 1–59 months in sub-Saharan Africa and South Asia from 2016 to 2022: an observational study

Author

Mahtab, Sana, primary, Blau, Dianna M, additional, Madewell, Zachary J, additional, Ogbuanu, Ikechukwu, additional, Ojulong, Julius, additional, Lako, Sandra, additional, Legesse, Hailemariam, additional, Bangura, Joseph S, additional, Bassat, Quique, additional, Mandomando, Inacio, additional, Xerinda, Elisio, additional, Fernandes, Fabiola, additional, Varo, Rosauro, additional, Sow, Samba O, additional, Kotloff, Karen L, additional, Tapia, Milagritos D, additional, Keita, Adama Mamby, additional, Sidibe, Diakaridia, additional, Onyango, Dickens, additional, Akelo, Victor, additional, Gethi, Dickson, additional, Verani, Jennifer R, additional, Revathi, Gunturu, additional, Scott, J Anthony G, additional, Assefa, Nega, additional, Madrid, Lola, additional, Bizuayehu, Hiwot, additional, Tirfe, Tseyon Tesfaye, additional, El Arifeen, Shams, additional, Gurley, Emily S, additional, Islam, Kazi Munisul, additional, Alam, Muntasir, additional, Zahid Hossain, Mohammad, additional, Dangor, Ziyaad, additional, Baillie, Vicky L, additional, Hale, Martin, additional, Mutevedzi, Portia, additional, Breiman, Robert F, additional, Whitney, Cynthia G, additional, Madhi, Shabir A, additional, Adam, Yasmin, additional, Agaya, Janet, additional, Ahmed, A.S.M. Nawshad Uddin, additional, Ahmed, Dilruba, additional, Alemu, Addisu, additional, Ali, Solomon, additional, Ameh, Soter, additional, Aol, George, additional, Argeseanu, Solveig, additional, Ariuman, Farida, additional, Balogun, Oluseyi, additional, Bari, Sanwarul, additional, Basket, Margaret, additional, Begum, Ferdousi, additional, Bhandari, Manu, additional, Blevins, John, additional, Bunn, James, additional, Bursuc, Courtney, additional, Cain, Carrie Jo, additional, Chawana, Richard, additional, Chawla, Kiranpreet, additional, Chukwuegbo, Cornell, additional, Diarra, Kounandji, additional, Diarra, Tiéman, additional, Diaz, Maureen, additional, Duduyemi, Babatunde, additional, Fairchild, Karen D., additional, Flora, Meerjady Sabrina, additional, Fritz, Ashleigh, additional, Garel, Mischka, additional, Gaume, Brigitte, additional, Gizaw, Mahlet Abayneh, additional, Govender, Nelesh P., additional, Greene, Carol L., additional, Gure, Tadesse, additional, Halu, Binyam, additional, Hoque, Mahbubul, additional, Hwinya, Cleopas, additional, Ibrahim, Alexander M., additional, Igunza, Kitiezo Aggrey, additional, Islam, Ferdousi, additional, Ita, Okokon, additional, Jambai, Amara, additional, Johnson, J. Kristie, additional, Juma, Jane, additional, Kaluma, Erick, additional, Kamal, Mohammed, additional, Kaykay, Osman, additional, Kenneh, Sartie, additional, Khagayi, Sammy, additional, Koka, Rima, additional, Kone, Diakaridia, additional, Koplan, Jeffrey P., additional, Kourouma, Nana, additional, Kowuor, Dickens, additional, LaHatte, Kristin, additional, Lala, Sanjay G., additional, Lee, Kyu Han, additional, Liu, Lucy, additional, Lombaard, Hennie, additional, Maixenchs, Maria, additional, Manhique, Zara, additional, Mannah, Margaret, additional, Martines, Roosecelis, additional, Mash, Ronald, additional, Mehta, Ashka, additional, Menéndez, Clara, additional, Misore, Thomas, additional, Mocumbi, Sibone, additional, Moseray, Andrew, additional, Moses, Francis, additional, Muga, Christopher, additional, Munguambe, Khátia, additional, Myburgh, Nellie, additional, Nair, Shailesh, additional, Ndagurwa, Pedzisai, additional, Nhacolo, Ariel, additional, Nhampossa, Tacilta, additional, Nwajiobi, Princewill, additional, Ochola, Christine, additional, Oliech, Richard, additional, Oluoch, Bernard, additional, Onwuchekwa, Uma U., additional, Onyango, Peter Nyamthimba, additional, Orlien, Stian MS, additional, Otieno, Peter, additional, Oundo, Joseph, additional, Owuor, Harun, additional, Parveen, Shahana, additional, Petersen, Karen, additional, Pratt, Samuel, additional, Rahman, Mahbubur, additional, Rahman, Mohammad Mosiur, additional, Rahman, Mustafizur, additional, Raymer, Sarah, additional, Ritter, Jana, additional, Salzberg, Navit T., additional, Samura, Solomon, additional, Sannoh, Sulaiman, additional, Sanogo, Doh, additional, Seppeh, Martin, additional, Sesay, Tom, additional, Sesay, Joseph Kamanda, additional, Shirin, Tahmina, additional, Sissoko, Seydou, additional, Smart, Francis, additional, Sorour, Gillian, additional, Squire, James, additional, Swaray-Deen, Alim, additional, Swart, Peter J., additional, Tarawally, Fatmata Bintu, additional, Tasnim, Saria, additional, Temesgen, Fikremelekot, additional, Tennant, Sharon M., additional, Traore, Cheick Bougadari, additional, Traore, Awa, additional, Velaphi, Sithembiso, additional, Vyas, Kurt, additional, Wadhwa, Ashutosh, additional, Wadula, Jeannette, additional, Waller, Jessica, additional, Wanga, Valentine, additional, Warang, Shamta, additional, Were, Joyce Akinyi, additional, Wilson, Tais, additional, Winchell, Jonas, additional, Wise, Amy, additional, Witherbee, Jakob, additional, Yeshi, Melisachew Mulatu, additional, and Zaman, K., additional

Published
2024
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23. Responses to Bacteria, Virus, and Malaria Distinguish the Etiology of Pediatric Clinical Pneumonia

Author

Valim, Clarissa, Ahmad, Rushdy, Lanaspa, Miguel, Tan, Yan, Acácio, Sozinho, Gillette, Michael A, Almendinger, Katherine D, Milner, Danny A, Madrid, Lola, Pellé, Karell, Harezlak, Jaroslaw, Silterra, Jacob, Alonso, Pedro L, Carr, Steven A, Mesirov, Jill P, Wirth, Dyann F, Wiegand, Roger C, and Bassat, Quique

Subjects
Pneumonia & Influenza, Vector-Borne Diseases, Pediatric, Lung, Clinical Research, Emerging Infectious Diseases, Rare Diseases, Pneumonia, Infectious Diseases, 4.1 Discovery and preclinical testing of markers and technologies, Detection, screening and diagnosis, 4.2 Evaluation of markers and technologies, Infection, Good Health and Well Being, Biomarkers, Child, Preschool, Diagnosis, Differential, Female, Haptoglobins, Humans, Immunoassay, Infant, Malaria, Male, Matrix Metalloproteinase 1, Pneumonia, Bacterial, Pneumonia, Viral, Receptors, Interleukin-10, Receptors, Tumor Necrosis Factor, Type II, Reproducibility of Results, Sensitivity and Specificity, biomarkers, pneumonia, immunoassay, bacteria, Medical and Health Sciences, Respiratory System
Abstract

RationalePlasma-detectable biomarkers that rapidly and accurately diagnose bacterial infections in children with suspected pneumonia could reduce the morbidity of respiratory disease and decrease the unnecessary use of antibiotic therapy.ObjectivesUsing 56 markers measured in a multiplexed immunoassay, we sought to identify proteins and protein combinations that could discriminate bacterial from viral or malarial diagnoses.MethodsWe selected 80 patients with clinically diagnosed pneumonia (as defined by the World Health Organization) who also met criteria for bacterial, viral, or malarial infection based on clinical, radiographic, and laboratory results. Ten healthy community control subjects were enrolled to assess marker reliability. Patients were subdivided into two sets: one for identifying potential markers and another for validating them.Measurements and main resultsThree proteins (haptoglobin, tumor necrosis factor receptor 2 or IL-10, and tissue inhibitor of metalloproteinases 1) were identified that, when combined through a classification tree signature, accurately classified patients into bacterial, malarial, and viral etiologies and misclassified only one patient with bacterial pneumonia from the validation set. The overall sensitivity and specificity of this signature for the bacterial diagnosis were 96 and 86%, respectively. Alternative combinations of markers with comparable accuracy were selected by support vector machine and regression models and included haptoglobin, IL-10, and creatine kinase-MB.ConclusionsCombinations of plasma proteins accurately identified children with a respiratory syndrome who were likely to have bacterial infections and who would benefit from antibiotic therapy. When used in conjunction with malaria diagnostic tests, they may improve diagnostic specificity and simplify treatment decisions for clinicians.

Published
2016

25. Causes of Stillbirth in Sub-Saharan Africa and South Asia: Findings from Child Health and Mortality Prevention Surveillance, 2016-2021

Author

Rahman, Afruna, primary, Lee, Kyu Han, additional, Arifeen, Shams, additional, Zahid hossain, Mohammad, additional, Chowdhury, Atique Iqbal, additional, Alam, Munatsir, additional, Afrin, Afsana, additional, Ogbuanu, Ikechukwu U., additional, Samura, Solomon, additional, Kaluma, Erick, additional, Ojulong, Julius, additional, Sow, Samba O., additional, Keita, Adama Mamby, additional, Tapia, Milagritos D., additional, Chawla, Kiranpreet Kaur, additional, Kotloff, Karen L., additional, Madhi, Shabir Ahmed, additional, Mahtab, Sana, additional, Adam, Yasmin, additional, Wise, Amy, additional, Dangor, Ziyaad, additional, Mugah, Christopher, additional, Oele, Elizabeth, additional, Omore, Richard, additional, Igunza, Kitiezo Aggrey, additional, Onyango, Dickens, additional, Mandomando, Inacio, additional, Bassat, Quique, additional, Ajanovic, Sara, additional, Varo, Rosauro, additional, Xerinda, Elisio, additional, Assefa, Nega, additional, Scott, J. Anthony G., additional, Madrid, Lola, additional, Yeshi, Melisachew M., additional, Temesgen, Fikremelekot, additional, Liu, Lucy, additional, Mutevedzi, Portia, additional, Blau, Dianna M., additional, Breiman, Robert, additional, Whitney, Cynthia G., additional, Gurley, Emily S., additional, and Consortium, CHAMPS, additional

Published
2024
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26. OA-429 High mortality in African infants living with HIV hospitalized with severe pneumonia

Author

Nduna, Bwendo, primary, Moraleda, Cinta, additional, Sacaral, Jahit, additional, Beinomugisha, Judith, additional, Zulu, Idah, additional, Chitamatanga, Moses, additional, Tam, Pui-Ying Iroh, additional, Chawinga, Chimwemwe, additional, Fernandez, Sheila, additional, Ballesteros, Álvaro, additional, Passanduca, Alfeu, additional, Tagoola, Abner, additional, Atibo, Raul, additional, Nansera, Denis, additional, Bwakura-Dangarembizi, Mutsa, additional, Gambi, Lughano, additional, Mvalo, Tisungane, additional, Madrid, Lola, additional, Macmillan, Belinda, additional, Musiime, Victor, additional, Moh, Raoul, additional, Buck, Chris W, additional, Chabala, Chishala, additional, Tagarro, Alfredo, additional, Rojo, Pablo, additional, and Empirical, Trial, additional

Published
2023
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27. OA-286 Plasma concentrations of first line antituberculosis drugs in infants with HIV and severe pneumonia: a pharmacokinetic sub-study of the empirical trial

Author

Chabala, Chishala, primary, Jacobs, Tom, additional, Moraleda, Cinta, additional, Mumbiro, Vivian, additional, Namuziya, Natasha, additional, Mutesi, Sophie, additional, Domínguez-Rodríguez, Sara, additional, Chitsamatanga, Moses, additional, Casia, Uneisse, additional, Nalwanga, Damalie, additional, Nduna, Bwendo, additional, Lajara, Nancy, additional, Ballesteros, Alvaro, additional, Madrid, Lola, additional, Nathoo, Kusum, additional, Mulenga, Veronica, additional, Buck, Chris, additional, Musiime, Victor, additional, Mujuru, Hilda, additional, Tagarro, Alfredo, additional, Brake, Lindsey te, additional, Aarnoutse, Rob, additional, Rojo, Pablo, additional, and Burger, David, additional

Published
2023
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28. Provider adherence to clinical care recommendations for infants and children who died in seven low- and middle-income countries in the Child Health and Mortality Prevention Surveillance (CHAMPS) network

Author

Rees, Chris A., primary, Igunza, Kitiezo Aggrey, additional, Madewell, Zachary J., additional, Akelo, Victor, additional, Onyango, Dickens, additional, El Arifeen, Shams, additional, Gurley, Emily S., additional, Hossain, Mohammad Zahid, additional, Rahman, Afruna, additional, Alam, Muntasir, additional, Scott, J. Anthony G., additional, Assefa, Nega, additional, Madrid, Lola, additional, Belachew, Anteneh, additional, Leulseged, Haleluya, additional, Kotloff, Karen L., additional, Sow, Samba O., additional, Tapia, Milagritos D., additional, Keita, Adama Mamby, additional, Sidibe, Diakaridia, additional, Sitoe, Antonio, additional, Varo, Rosauro, additional, Ajanovic, Sara, additional, Bassat, Quique, additional, Mandomando, Inácio, additional, Tippett Barr, Beth A., additional, Ogbuanu, Ikechukwu, additional, Cain, Carrie Jo, additional, Bassey, Ima-Abasi, additional, Luke, Ronita, additional, Gassama, Khadija, additional, Madhi, Shabir, additional, Dangor, Ziyaad, additional, Mahtab, Sana, additional, Velaphi, Sithembiso, additional, du Toit, Jeanie, additional, Mutevedzi, Portia C., additional, Blau, Dianna M., additional, Breiman, Robert F., additional, Whitney, Cynthia G., additional, Solomon, Fatima, additional, Sorour, Gillian, additional, Lombaard, Hennie, additional, Wadula, Jeannette, additional, Petersen, Karen, additional, Hale, Martin, additional, Govender, Nelesh P., additional, Swart, Peter J., additional, Lala, Sanjay G., additional, Chawana, Richard, additional, Adam, Yasmin, additional, Wise, Amy, additional, Fritz, Ashleigh, additional, Myburgh, Nellie, additional, Ndagurwa, Pedzisai, additional, Hwinya, Cleopas, additional, Bari, Sanwarul, additional, Parveen, Shahana, additional, Kamal, Mohammed, additional, Uddin Ahmed, A.S.M. Nawshad, additional, Hoque, Mahbubul, additional, Tasnim, Saria, additional, Islam, Ferdousi, additional, Ariuman, Farida, additional, Rahman, Mohammad Mosiur, additional, Begum, Ferdousi, additional, Zaman, K., additional, Rahman, Mustafizur, additional, Ahmed, Dilruba, additional, Flora, Meerjady Sabrina, additional, Shirin, Tahmina, additional, Rahman, Mahbubur, additional, Oundo, Joseph, additional, Ibrahim, Alexander M., additional, Temesgen, Fikremelekot, additional, Gure, Tadesse, additional, Alemu, Addisu, additional, Yeshi, Melisachew Mulatu, additional, Gizaw, Mahlet Abayneh, additional, Orlien, Stian, additional, Ali, Solomon, additional, Otieno, Peter, additional, Onyango, Peter Nyamthimba, additional, Agaya, Janet, additional, Oliech, Richard, additional, Were, Joyce Akinyi, additional, Gethi, Dickson, additional, Khagayi, Sammy, additional, Aol, George, additional, Misore, Thomas, additional, Owuor, Harun, additional, Mugah, Christopher, additional, Oluoch, Bernard, additional, Ochola, Christine, additional, Tennant, Sharon M., additional, Greene, Carol L., additional, Mehta, Ashka, additional, Johnson, J. Kristie, additional, Gaume, Brigitte, additional, Koka, Rima, additional, Fairchild, Karen D., additional, Kone, Diakaridia, additional, Sanogo, Doh, additional, Onwuchekwa, Uma U., additional, Kourouma, Nana, additional, Sissoko, Seydou, additional, Traore, Cheick Bougadari, additional, Juma, Jane, additional, Diarra, Kounandji, additional, Traore, Awa, additional, Diarra, Tiéman, additional, Chawla, Kiranpreet, additional, Nhampossa, Tacilta, additional, Manhique, Zara, additional, Mocumbi, Sibone, additional, Menéndez, Clara, additional, Munguambe, Khátia, additional, Nhacolo, Ariel, additional, Maixenchs, Maria, additional, Moseray, Andrew, additional, Tarawally, Fatmata Bintu, additional, Seppeh, Martin, additional, Mash, Ronald, additional, Ojulong, Julius, additional, Duduyemi, Babatunde, additional, Bunn, James, additional, Swaray-Deen, Alim, additional, Bangura, Joseph, additional, Jambai, Amara, additional, Mannah, Margaret, additional, Ita, Okokon, additional, Chukwuegbo, Cornell, additional, Sannoh, Sulaiman, additional, Nwajiobi, Princewill, additional, Kowuor, Dickens, additional, Kaluma, Erick, additional, Balogun, Oluseyi, additional, Samura, Solomon, additional, Pratt, Samuel, additional, Moses, Francis, additional, Sesay, Tom, additional, Squire, James, additional, Sesay, Joseph Kamanda, additional, Kaykay, Osman, additional, Halu, Binyam, additional, Legesse, Hailemariam, additional, Smart, Francis, additional, Kenneh, Sartie, additional, Ameh, Soter, additional, Ritter, Jana, additional, Wilson, Tais, additional, Winchell, Jonas, additional, Witherbee, Jakob, additional, Salzberg, Navit T., additional, Koplan, Jeffrey P., additional, Basket, Margaret, additional, Wadhwa, Ashutosh, additional, Lee, Kyu Han, additional, Wanga, Valentine, additional, Martines, Roosecelis, additional, Warang, Shamta, additional, Diaz, Maureen, additional, Waller, Jessica, additional, Nair, Shailesh, additional, Liu, Lucy, additional, Bursuc, Courtney, additional, LaHatte, Kristin, additional, Raymer, Sarah, additional, Blevins, John, additional, Argeseanu, Solveig, additional, Vyas, Kurt, additional, and Bhandari, Manu, additional

Published
2023
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29. Postmortem investigations and identification of multiple causes of child deaths: An analysis of findings from the Child Health and Mortality Prevention Surveillance (CHAMPS) network

Author

Breiman, Robert F., Blau, Dianna M., Mutevedzi, Portia, Akelo, Victor, Mandomando, Inacio, Ogbuanu, Ikechukwu U., Sow, Samba O., Madrid, Lola, El Arifeen, Shams, Garel, Mischka, Thwala, Nana Bukiwe, Onyango, Dickens, Sitoe, Antonio, Bassey, Ima-Abasi, Keita, Adama Mamby, Alemu, Addisu, Alam, Muntasir, Mahtab, Sana, Gethi, Dickson, Varo, Rosauro, Ojulong, Julius, Samura, Solomon, Mehta, Ashka, Ibrahim, Alexander M., Rahman, Afruna, Vitorino, Pio, Baillie, Vicky L., Agaya, Janet, Tapia, Milagritos D., Assefa, Nega, Chowdhury, Atique Iqbal, Scott, J. Anthony G., Gurley, Emily S., Kotloff, Karen L., Jambai, Amara, Bassat, Quique, Tippett-Barr, Beth A., Madhi, Shabir A., and Whitney, Cynthia G.

Subjects
Pediatric research, Children -- Death, Company legal issue, Biological sciences
Abstract

Background The current burden of >5 million deaths yearly is the focus of the Sustainable Development Goal (SDG) to end preventable deaths of newborns and children under 5 years old by 2030. To accelerate progression toward this goal, data are needed that accurately quantify the leading causes of death, so that interventions can target the common causes. By adding postmortem pathology and microbiology studies to other available data, the Child Health and Mortality Prevention Surveillance (CHAMPS) network provides comprehensive evaluations of conditions leading to death, in contrast to standard methods that rely on data from medical records and verbal autopsy and report only a single underlying condition. We analyzed CHAMPS data to characterize the value of considering multiple causes of death. Methods and findings We examined deaths identified from December 2016 through November 2020 from 7 CHAMPS sites (in Bangladesh, Ethiopia, Kenya, Mali, Mozambique, Sierra Leone, and South Africa), including 741 neonatal, 278 infant, and 241 child Conclusions Including conditions that appear anywhere in the causal chain, rather than considering underlying condition alone, markedly changed the proportion of deaths attributed to various diagnoses, especially LRI, sepsis, and meningitis. While CHAMPS methods cannot determine when 2 conditions cause death independently or may be synergistic, our findings suggest that considering the chain of events leading to death can better guide research and prevention priorities aimed at reducing child deaths., Author(s): Robert F. Breiman 1,2,*, Dianna M. Blau 3, Portia Mutevedzi 4,5, Victor Akelo 6, Inacio Mandomando 7,8, Ikechukwu U. Ogbuanu 9, Samba O. Sow 10,11, Lola Madrid 12,13, Shams [...]

Published
2021
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30. Mortality associated with third-generation cephalosporin resistance in Enterobacterales bloodstream infections at eight sub-Saharan African hospitals (MBIRA): a prospective cohort study

Author

Aiken, Alexander M, primary, Rehman, Andrea M, additional, de Kraker, Marlieke E A, additional, Madrid, Lola, additional, Kebede, Meron, additional, Labi, Appiah-Korang, additional, Obeng-Nkrumah, Noah, additional, Nyamwaya, Brian, additional, Kagucia, Eunice, additional, Cocker, Derek, additional, Kawaza, Kondwani, additional, Lester, Rebecca, additional, Iregbu, Kenneth C, additional, Medugu, Nubwa, additional, Nwajiobi-Princewill, Philip I, additional, Dramowski, Angela, additional, Sonda, Tolbert, additional, Hemed, Asia, additional, Fwoloshi, Sombo, additional, Ojok, David, additional, Scott, J Anthony G, additional, Whitelaw, Andrew, additional, Aliye, Jabir, additional, Assefa, Nega, additional, Edessa, Dumessa, additional, Oundo, Joseph, additional, Berihun, Mulu, additional, Dankwah, Thomas, additional, Osei, Mary M, additional, Fandoh, Maud, additional, Gakpo, Margaret, additional, Mulunda, Caroline, additional, Mvera, Benedict, additional, Chimenya, Mabvuto, additional, Feasey, Nicholas, additional, Mallewa, Jane, additional, Abdulraheem, Khadija, additional, Akujobi, Tobechi A, additional, Okonkwo, Chinelo H, additional, Britz, Luzell, additional, Bulbula, André N H, additional, Fataar, Aaqilah, additional, Mmbaga, Blandina T, additional, Ng'unda, Neema, additional, Chirwa, Uchizi, additional, Kakula, Nyambe, additional, Mutemba, Charles, additional, and Nakazwe, Ruth, additional

Published
2023
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31. Neural tube defects as a cause of death among stillbirths, infants, and children younger than 5 years in sub-Saharan Africa and southeast Asia: an analysis of the CHAMPS network

Author

Madrid, Lola, primary, Vyas, Kartavya J, additional, Kancherla, Vijaya, additional, Leulseged, Haleluya, additional, Suchdev, Parminder S, additional, Bassat, Quique, additional, Sow, Samba O, additional, El Arifeen, Shams, additional, Madhi, Shabir A, additional, Onyango, Dickens, additional, Ogbuanu, Ikechukwu, additional, Scott, J Anthony G, additional, Blau, Dianna, additional, Mandomando, Inacio, additional, Keita, Adama M, additional, Gurley, Emily S, additional, Mahtab, Sana, additional, Akelo, Victor, additional, Sannoh, Sulaiman, additional, Tilahun, Yenenesh, additional, Varo, Rosauro, additional, Onwuchekwa, Uma, additional, Rahman, Afruna, additional, Adam, Yasmin, additional, Omore, Richard, additional, Lako, Sandra, additional, Xerinda, Elisio, additional, Islam, Kazi Munisul, additional, Wise, Amy, additional, Tippet-Barr, Beth A, additional, Kaluma, Erick, additional, Ajanovic, Sara, additional, Kotloff, Karen L, additional, Hossain, Mohammad Zahid, additional, Mutevedzi, Portia, additional, Tapia, Milagritos D, additional, Rogena, Emily, additional, Moses, Francis, additional, Whitney, Cynthia G, additional, Assefa, Nega, additional, Nawshad Uddin Ahmed, A.S.M., additional, Hoque, Mahbubul, additional, Kamal, Mohammed, additional, Mosiur, Mohammad, additional, Begum, Ferdousi, additional, Tasnim, Saria, additional, Flora, Meerjady Sabrina, additional, Arjuman, Farida, additional, Khan, Iqbal Ansary, additional, Shirin, Tahmina, additional, Rahman, Mahbubur, additional, Bari, Sanwarul, additional, Parveen, Shahana, additional, Islam, Farzana, additional, Ahmed, Mohammad Sabbir, additional, Zaman, K, additional, Rahman, Mustafizur, additional, Ahmed, Dilruba, additional, Chowdhury, Md Atique Iqbal, additional, Alam, Muntasir, additional, Lee, Kyu Han, additional, Islam, Ferdousi, additional, Oundo, Joseph O, additional, Temesgen, Fikremelekot, additional, Yeshi, Melisachew Mulatu, additional, Ibrahim, Alexander M, additional, Gure, Tadesse, additional, Edris, Yunus, additional, Alemu, Addisu, additional, Marami, Dadi, additional, Lemma, Ephrem, additional, Mekonnen, Ayantu, additional, Wale, Henok, additional, Tesfaye, Tseyon, additional, Dufera, Tadesse, additional, Belachew, Anteneh, additional, Getnet, Fentabil, additional, Fentaw, Surafel, additional, Acham, Yenework, additional, Orlien, Stian MS, additional, Abayneh Gizaw, Mahlet, additional, Murila, Florence, additional, Revathi, Gunturu, additional, Mitei, Paul K, additional, Kuria, Magdalene, additional, Verani, Jennifer R, additional, Igunza, Aggrey, additional, Nyamthimba, Peter, additional, Oele, Elizabeth, additional, Fairchild, Karen D, additional, Greene, Carol L, additional, Koka, Rima, additional, Mehta, Ashka, additional, Tennant, Sharon M, additional, Johnson, J Kristie, additional, Keita, Tatiana, additional, Keita, Adama Mamby, additional, Kourouma, Nana, additional, Onwuchekwa, Uma U, additional, Traore, Awa, additional, Sanogo, Doh, additional, Sidibe, Diakaridia, additional, Sissoko, Seydou, additional, Kone, Diakaridia, additional, Kindcardett, Milton, additional, Munguambe, Khátia, additional, Nhacolo, Ariel, additional, Nhampossa, Tacilta, additional, Vitorino, Pio, additional, Bramugy, Justina, additional, Monjane, Celso, additional, Nhachungue, Sheila, additional, Hurtado, Juan Carlos, additional, Maixenchs, Maria, additional, Menéndez, Clara, additional, Ordi, Jaume, additional, Rakislova, Natalia, additional, Valente, Marta, additional, Manhique, Zara, additional, Chitungo, Dercio, additional, Mocumbi, Sibone, additional, Carrilho, Carla, additional, Fernandes, Fabiola, additional, Pass Philipsborn, Rebecca, additional, Koplan, Jeffrey P, additional, Garel, Mischka, additional, Dewey, Betsy, additional, Nair, Shailesh, additional, Salzberg, Navit T, additional, Liu, Lucy, additional, Alkis-Ramirez, Rebecca, additional, Ritter, Jana M, additional, Zaki, Sherif R, additional, Gary, Joy, additional, Winchell, Jonas M, additional, Witherbee, Jacob, additional, Waller, Jessica L, additional, Fayorsey, Ruby, additional, Luke, Ronita, additional, Bassey, Ima-Abasi, additional, Kowuor, Dickens, additional, Sesay, Foday, additional, Kosia, Baindu, additional, Pratt, Samuel, additional, Cain, Carrie-Jo, additional, Samura, Solomon, additional, Solomon, Fatima, additional, Fritz, Ashleigh, additional, Dludlu, Noluthando, additional, Ntuli, Constance, additional, Chawana, Richard, additional, Petersen, Karen, additional, Lala, Sanjay G, additional, Velaphi, Sithembiso, additional, Wadula, Jeannette, additional, Hale, Martin, additional, Swart, Peter J, additional, Lombaard, Hennie, additional, Moosa, Rahima, additional, and Sorour, Gillian, additional

Published
2023
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32. Causes of stillbirth and death among children younger than 5 years in eastern Hararghe, Ethiopia: a population-based post-mortem study

Author

Madrid, Lola, primary, Alemu, Addisu, additional, Seale, Anna C, additional, Oundo, Joe, additional, Tesfaye, Tseyon, additional, Marami, Dadi, additional, Yigzaw, Hiwot, additional, Ibrahim, Alexander, additional, Degefa, Ketema, additional, Dufera, Tadesse, additional, Teklemariam, Zelalem, additional, Gure, Tadesse, additional, Leulseged, Haleluya, additional, Wittmann, Stefanie, additional, Abayneh, Mahlet, additional, Fentaw, Surafel, additional, Temesgen, Fikremelekot, additional, Yeshi, Melisachew M, additional, Dubale, Mehret, additional, Girma, Zerihun, additional, Ackley, Caroline, additional, Damisse, Berhanu, additional, Breines, Markus, additional, Orlien, Stian M S, additional, Blau, Dianna M, additional, Breiman, Robert F, additional, Abate, Ebba, additional, Dessie, Yadeta, additional, Assefa, Nega, additional, Scott, J Anthony G, additional, Deresa, Merga, additional, Mengesha, Gezahegn, additional, Samuel, Tigistu, additional, Taye, Eyoel, additional, Aliyi, Mohammed, additional, Feyissa, Gurmu, additional, Tilahun, Yenenesh, additional, Wakwaya, Getahun, additional, Tadesse, Simegn, additional, Asnake, Kidish, additional, Ayalew, Mariamcher, additional, Kidane, Azeb, additional, Azore, Emmanuel, additional, Berhanu, Mussie, additional, Berihun, Mulu, additional, Deresa, Mersan, additional, Assegid, Nardos, additional, Voller, Shirine, additional, Mekonnen, Mahlet, additional, Alemaheyu, Andualem, additional, Sarkodie-Mensah, Nana, additional, Morrison, Beth, additional, Jibendi, Boniface, additional, Worku, Asnake, additional, Mirkuzie, Alemenesh, additional, and Getnet, Fentabil, additional

Published
2023
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34. Prognostic accuracy of biomarkers of immune and endothelial activation in Mozambican children hospitalized with pneumonia

Author

Balanza, Núria, primary, Erice, Clara, additional, Ngai, Michelle, additional, McDonald, Chloe R., additional, Weckman, Andrea M., additional, Wright, Julie, additional, Richard-Greenblatt, Melissa, additional, Varo, Rosauro, additional, López-Varela, Elisa, additional, Sitoe, Antonio, additional, Vitorino, Pio, additional, Bramugy, Justina, additional, Lanaspa, Miguel, additional, Acácio, Sozinho, additional, Madrid, Lola, additional, Baro, Bàrbara, additional, Kain, Kevin C., additional, and Bassat, Quique, additional

Published
2023
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35. Mortality Associated with 3 rd Generation Cephalosporin Resistance in Enterobacterales Bloodstream Infections at Eight Sub-Saharan African Hospitals, a Prospective Cohort Study (MBIRA)

Author

Aiken, Alexander Michael, primary, Rehman, Andrea M., additional, de Kraker, Marlieke E. A., additional, Madrid, Lola, additional, Kebede, Meron, additional, Labi, Appiah-Korang, additional, Obeng-Nkrumah, Noah, additional, Nyamwaya, Brian, additional, Kagucia, Wangeci, additional, Cocker, Derek, additional, Kawaza, Kondwani, additional, Lester, Rebecca, additional, Iregbu, Kenneth C., additional, Medugu, Nubwa, additional, Nwajiobi-Princewill, Philip I., additional, Dramowski, Angela, additional, Sonda, Tolbert B., additional, Hemed, Asia, additional, Fwoloshi, Sombo, additional, Ojok, David, additional, Scott, J. Anthony G., additional, Whitelaw, Andrew, additional, Aliye, Jabir, additional, Assefa, Nega, additional, Edessa, Dumessa, additional, Oundo, Joe, additional, Berihun, Mulu, additional, Dankwah, Thomas, additional, Osei, Mary M., additional, Fandoh, Maud, additional, Mulunda, Caroline, additional, Mvera, Benedict, additional, Chimenya, Mabvuto, additional, Feasey, Nicholas A., additional, Mallewa, Jane, additional, Akujobi, Tobechi A., additional, Okonkwo, Chinelo H., additional, Britz, Luzell, additional, Bulabula, Andre, additional, Fataar, Aaqilah, additional, Mmbaga, Blandina T., additional, Ng'unda, Neema, additional, Chirwa, Uchizi, additional, Kakula, Nyambe, additional, Mutemba, Charles, additional, and Nakazwe, Ruth, additional

Published
2023
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37. Stillbirths and Neonatal Deaths Caused by Group B Streptococcus in Africa and South Asia Identified Through Child Health and Mortality Prevention Surveillance (CHAMPS).

Author

Mahtab, Sana, Madewell, Zachary J, Madhi, Shabir A, Wise, Amy, Swart, Peter J, Velaphi, Sithembiso, Mandomando, Inacio, Bramugy, Justina, Mabunda, Rita, Xerinda, Elisio, Scott, Anthony G, Assefa, Nega, Madrid, Lola, Bweihun, Mulu, Temesgen, Fikremelekot, Onyango, Dickens, Akelo, Victor, Oliech, Richard, Otieno, Peter, and Verani, Jennifer R

Subjects
STREPTOCOCCUS agalactiae, CHILD mortality, NEONATAL death, NEONATAL sepsis, STILLBIRTH, CAUSES of death
Abstract

Background Invasive Group B Streptococcus (GBS) is a common cause of early-onset neonatal sepsis and is also associated with stillbirth. This study aimed to determine the proportion of stillborn infants and infants who died between 0 and 90 days attributable to GBS using postmortem minimally invasive tissue sampling (MITS) in 7 low- and middle-income countries (LMICs) participating in Child Health and Mortality Prevention Surveillance (CHAMPS). Methods Deaths that occurred between December 2016 and December 2021 were investigated with MITS, including culture for bacteria of blood and cerebrospinal fluid (CSF), multipathogen polymerase chain reaction on blood, CSF, and lung tissue and histopathology of lung, liver, and brain. Data collection included clinical record review and verbal autopsy. Expert panels reviewed all information and assigned causes of death. Results We evaluated 2966 deaths, including stillborn infants (n = 1322), infants who died during first day of life (0 to <24 hours, n = 597), early neonatal deaths (END) (1 day to <7 days; END; n = 593), and deaths from 7 to 90 days (n = 454). Group B Streptococcus was determined to be in the causal pathway of death for 2.7% of infants (79 of 2, 966; range, 0.3% in Sierra Leone to 7.2% in South Africa), including 2.3% (31 of 1322) of stillbirths, 4.7% (28 of 597) 0 to <24 hours, 1.9% (11 of 593) END, and 2.0% (9 of 454) of deaths from 7 to 90 days of age. Among deaths attributed to GBS with birth weight data available, 61.9% (39 of 63) of decedents weighed <2500 grams at birth. Group B Streptococcus sepsis was the postmortem diagnosis for 100% (31 of 31) of stillbirths. For deaths <90 days, postmortem diagnoses included GBS sepsis (83.3%, 40 of 48), GBS meningitis (4.2%, 2 of 48), and GBS pneumonia (2.1%, 1 of 48). Conclusions Our study reveals significant heterogeneity in the contribution of invasive GBS disease to infant mortality across different countries, emphasizing the need for tailored prevention strategies. Moreover, our findings highlight the substantial impact of GBS on stillbirths, shedding light on a previously underestimated aspect in LMICs. [ABSTRACT FROM AUTHOR]

Published
2023
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38. Treatment and control of invasive Gram-negative bacterial infection in eight hospitals across sub-Saharan Africa: a cross-sectional study

Author

Aiken, Alexander M., primary, Nyamwaya, Brian, additional, Madrid, Lola, additional, Edessa, Dumessa, additional, Labi, Appiah-Korang, additional, Obeng-Nkrumah, Noah, additional, Mwabaya, William, additional, Chimenya, Mabvuto, additional, Cocker, Derek, additional, Iregbu, Kenneth C., additional, Nwajiobi-Princewill, Philip I.P., additional, Dramowski, Angela, additional, Sonda, Tolbert, additional, Mmbaga, Blandina Theophil, additional, Ojok, David, additional, Fwoloshi, Sombo, additional, Scott, J. Anthony G., additional, Whitelaw, Andrew, additional, and collaborators, MBIRA study, additional

Published
2022
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39. Insights on the differentiation of stillbirths and early neonatal deaths: A study from the Child Health and Mortality Prevention Surveillance (CHAMPS) network

Author

Quincer, Elizabeth, primary, Philipsborn, Rebecca, additional, Morof, Diane, additional, Salzberg, Navit T., additional, Vitorino, Pio, additional, Ajanovic, Sara, additional, Onyango, Dickens, additional, Ogbuanu, Ikechukwu, additional, Assefa, Nega, additional, Sow, Samba O., additional, Mutevedzi, Portia, additional, El Arifeen, Shams, additional, Tippet Barr, Beth A., additional, Scott, J. Anthony G., additional, Mandomando, Inacio, additional, Kotloff, Karen L., additional, Jambai, Amara, additional, Akelo, Victor, additional, Cain, Carrie Jo, additional, Chowdhury, Atique Iqbal, additional, Gure, Tadesse, additional, Igunza, Kitiezo Aggrey, additional, Islam, Farzana, additional, Keita, Adama Mamby, additional, Madrid, Lola, additional, Mahtab, Sana, additional, Mehta, Ashka, additional, Mitei, Paul K., additional, Ntuli, Constance, additional, Ojulong, Julius, additional, Rahman, Afruna, additional, Samura, Solomon, additional, Sidibe, Diakaridia, additional, Thwala, Bukiwe Nana, additional, Varo, Rosauro, additional, Madhi, Shabir A., additional, Bassat, Quique, additional, Gurley, Emily S., additional, Blau, Dianna M., additional, and Whitney, Cynthia G., additional

Published
2022
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40. Setting up child health and mortality prevention surveillance in Ethiopia

Author

Seale, Anna C., primary, Assefa, Nega, additional, Madrid, Lola, additional, Wittmann, Stefanie, additional, Abdurahman, Hanan, additional, Teferi, Nardos, additional, Gedefa, Letta, additional, Mohamed, Alexander, additional, Debela, Natnael, additional, Tesfaye, Tseyon, additional, Samuel, Tigistu, additional, Dubale, Mehret, additional, Yigzaw, Hiwot, additional, Taye, Eyoel, additional, Bekele, Workalemahu, additional, Ackley, Caroline, additional, Keno, Gutema Imana, additional, Zegeye, Yosef, additional, Girma, Zerihun, additional, Degefa, Ketema, additional, Damisse, Berhanu, additional, Tadesse, Adugna, additional, Aliyi, Mohammed, additional, Feyissa, Gurmu, additional, Tilahun, Yenenesh, additional, Wakwaya, Getahun, additional, Sintayehu, Bizunesh, additional, Abayneh, Getamesay, additional, Alemu, Addisu, additional, Azore, Emmanuel, additional, Oundo, Joe, additional, Mariam, Zelalem T, additional, Marami, Dadi, additional, Berihun, Mulu, additional, Berhanu, Mussie, additional, Mekonnen, Mahlet, additional, Alemayehu, Andualem, additional, Sarkodie-Mensah, Nana, additional, Voller, Shirine, additional, Jibendi, Boniface, additional, Aseffa, Abraham, additional, Balcha, Taye, additional, F. Breiman, Robert, additional, Dowell, Scott F, additional, Worku, Asnake, additional, Kifle, Tsigereda, additional, Abate, Ebba, additional, Dessie, Yadeta, additional, and Scott, J. Anthony G., additional

Published
2022
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41. Causes of Stillbirth and Death Among Young Children in Eastern Hararghe, Ethiopia

Author

Madrid, Lola, primary, Alemu, Addisu, additional, Seale, Anna C., additional, Oundo, Joe, additional, Tesfaye, Tseyon, additional, Marami, Dadi, additional, Yigzaw, Hiwot, additional, Ibrahim, Alexander, additional, Degefa, Ketema, additional, Dufera, Tadesse, additional, Teklemariam, Zelalem, additional, Gure, Tadesse, additional, Leulseged, Haleluya, additional, Wittmann, Stefanie, additional, Abayneh, Mahlet, additional, Fentaw, Surafel, additional, Temesgen, Fikremelekot, additional, Yeshi, Melisachew M., additional, Dubale, Mehret, additional, Girma, Zerihun, additional, Ackley, Caroline, additional, Damisse, Berhanu, additional, Breines, Markus, additional, Orlien, Stian MS, additional, Blau, Dianna M., additional, Breiman, Robert, additional, Abate, Ebba, additional, Dessie, Yadeta, additional, Assefa, Nega, additional, and Scott, Anthony, additional

Published
2022
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42. Empirical Treatment Against Cytomegalovirus and Tuberculosis in HIV-Infected Infants with Severe Pneumonia: Study Protocol for a Multicenter, an Open-Label Randomized Controlled Clinical Trial

Author

Tagarro, Alfredo, primary, Moraleda, Cinta, additional, Dominguez, Sara, additional, Tam, Pui-Ying Iroh, additional, Buck, Christopher William, additional, Mujuru, Hilda Angela, additional, Musiime, Victor, additional, Sacarlal, Jahit, additional, Chabala, Chishala, additional, Leroy, Valerianne, additional, Bassat, Quique, additional, Marcy, Olivier, additional, Bates, Matthew, additional, Magallhaes, Justina, additional, Burger, David, additional, Nardone, Alessandra, additional, Moh, Raoul, additional, Mvalo, Tisungane, additional, Madrid, Lola, additional, Manukyan, Lilit, additional, Sancho, Aranzazu, additional, Prieto, Luis Manuel, additional, and Rojo, Pablo, additional

Published
2021
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43. Setting up child health and mortality prevention surveillance in Ethiopia

Author

Seale, Anna C., primary, Assefa, Nega, additional, Madrid, Lola, additional, Wittmann, Stefanie, additional, Abdurahman, Hanan, additional, Teferi, Nardos, additional, Gedefa, Letta, additional, Mohamed, Alexander, additional, Debela, Natnael, additional, Tesfaye, Tseyon, additional, Samuel, Tigistu, additional, Dubale, Mehret, additional, Yigzaw, Hiwot, additional, Taye, Eyoel, additional, Bekele, Workalemahu, additional, Ackley, Caroline, additional, Keno, Gutema Imana, additional, Zegeye, Yosef, additional, Girma, Zerihun, additional, Degefa, Ketema, additional, Damisse, Berhanu, additional, Tadesse, Adugna, additional, Aliyi, Mohammed, additional, Feyissa, Gurmu, additional, Tilahun, Yenenesh, additional, Wakwaya, Getahun, additional, Sintayehu, Bizunesh, additional, Abayneh, Getamesay, additional, Alemu, Addisu, additional, Azore, Emmanuel, additional, Oundo, Joe, additional, Mariam, Zelalem T, additional, Marami, Dadi, additional, Berihun, Mulu, additional, Berhanu, Mussie, additional, Mekonnen, Mahlet, additional, Alemayehu, Andualem, additional, Sarkodie-Mensah, Nana, additional, Voller, Shirine, additional, Jibendi, Boniface, additional, Aseffa, Abraham, additional, Balcha, Taye, additional, F. Breiman, Robert, additional, Dowell, Scott F, additional, Worku, Asnake, additional, Kifle, Tsigereda, additional, Abate, Ebba, additional, Dessie, Yadeta, additional, and Scott, J. Anthony G., additional

Published
2021
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49. Biomarkers to Distinguish Bacterial From Viral Pediatric Clinical Pneumonia in a Malaria-Endemic Setting

Author

Gillette, Michael A, primary, Mani, D R, additional, Uschnig, Christopher, additional, Pellé, Karell G, additional, Madrid, Lola, additional, Acácio, Sozinho, additional, Lanaspa, Miguel, additional, Alonso, Pedro, additional, Valim, Clarissa, additional, Carr, Steven A, additional, Schaffner, Stephen F, additional, MacInnis, Bronwyn, additional, Milner, Danny A, additional, Bassat, Quique, additional, and Wirth, Dyann F, additional

Published
2021
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50. Neurological Symptoms and Cause of Death Among Young Children in Low- and Middle-Income Countries.

Author

Ajanovic, Sara, Madewell, Zachary J., El Arifeen, Shams, Gurley, Emily S., Hossain, Mohammad Zahid, Islam, Kazi Munisul, Rahman, Afruna, Assefa, Nega, Madrid, Lola, Abdulahi, Mohammednur, Igunza, Kitiezo Aggrey, Murila, Florence, Revathi, Gunturu, Christopher, Mugah, Sow, Samba O., Kotloff, Karen L., Tapia, Milagritos D., Traor, Cheik Bougadari, Mandomando, Inacio, and Xerinda, Elisio

Published
2024
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