32 results on '"Maempel JF"'
Search Results
2. The speedboat vertebral fracture: a hazard of holiday watersports
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Maempel, JF, primary and Maempel, FZ, additional
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- 2018
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3. Surgery performed by supervised registrars does not adversely affect medium-term functional outcomes after total knee replacement
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Beattie, N, primary, Maempel, JF, additional, Roberts, S, additional, Waterson, HB, additional, Brown, G, additional, Brenkel, IJ, additional, and Walmsley, PJ, additional
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- 2018
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4. The speedboat vertebral fracture: a hazard of holiday watersports.
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Maempel, JF and Maempel, FZ
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- 2019
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5. Quantification of radiation exposure in the operating theatre during management of common fractures of the upper extremity in children
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Maempel, JF, primary, Stone, OD, additional, and Murray, AW, additional
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- 2016
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6. Enhanced recovery programmes can reduce length of stay after total knee replacement without sacrificing functional outcome at one year
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Maempel, JF, primary and Walmsley, PJ, additional
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- 2015
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7. Socioeconomic deprivation status predicts both the incidence and nature of Achilles tendon rupture.
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Maempel JF, Clement ND, Mackenzie SP, McCann C, and White TO
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- Adult, Humans, Male, Female, Middle Aged, Incidence, Prognosis, Socioeconomic Factors, Rupture epidemiology, Achilles Tendon injuries, Tendon Injuries epidemiology
- Abstract
Purpose: The aim of this study was to describe the epidemiology of Achilles tendon rupture (ATR) and its relationship with socioeconomic deprivation status (SEDS). The hypothesis was that ATR occurs more frequently in socioeconomically deprived patients. Secondary aims were to determine variations in circumstances of injury between more and less deprived patients., Methods: A 6-year retrospective review of consecutive patients presenting with ATR was undertaken. The health-board population was defined using governmental population data and SEDS was defined using the Scottish Index of Multiple Deprivation. The primary outcome was an epidemiological description and comparison of incidence in more and less deprived cohorts. Secondary outcomes included reporting of the relationship between SEDS and patient and injury characteristics with univariate and binary logistic regression analyses., Results: There were 783 patients (567 male; 216 female) with ATR. Mean incidence for adults (≥ 18 years) was 18.75/100,000 per year (range 16.56-23.57) and for all ages was 15.26/100,000 per year (range 13.51 to 19.07). Incidence in the least deprived population quintiles (4th and 5th quintiles; 18.07 per 100,000/year) was higher than that in the most deprived quintiles (1st and 2nd; 11.32/100,000 per year; OR 1.60, 95%CI 1.35-1.89; p < 0.001). When adjusting for confounding factors, least deprived patients were more likely to be > 50 years old (OR 1.97; 95%CI 1.24-3.12; p = 0.004), to sustain ATR playing sports (OR 1.72, 95%CI 1.11-2.67; p = 0.02) and in the spring (OR 1.65, 95%CI 1.01-2.70; p = 0.045) and to give a history of preceding tendinitis (OR 4.04, 95%CI 1.49-10.95; p = 0.006). They were less likely to sustain low-energy injuries (OR 0.44, 95%CI 0.23-0.87; p = 0.02) and to be obese (OR 0.25-0.41, 95%CI 0.07-0.90; p ≤ 0.03)., Conclusions: The incidence of ATR was higher in less socioeconomically deprived populations and the hypothesis was therefore rejected. Significant variations in patient and predisposing factors, mechanisms of injury and seasonality were demonstrated between most and least deprived groups, suggesting that circumstances and nature of ATR may vary with SEDS and these are not a homogenous group of injuries., Level of Evidence: Prognostic Study Level III., (© 2022. The Author(s) under exclusive licence to European Society of Sports Traumatology, Knee Surgery, Arthroscopy (ESSKA).)
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- 2023
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8. The epidemiology of Achilles tendon re-rupture and associated risk factors: male gender, younger age and traditional immobilising rehabilitation are risk factors.
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Maempel JF, White TO, Mackenzie SP, McCann C, and Clement ND
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- Adult, Case-Control Studies, Female, Humans, Male, Risk Factors, Rupture epidemiology, Rupture therapy, Achilles Tendon injuries, Achilles Tendon surgery, Ankle Injuries, Tendon Injuries epidemiology, Tendon Injuries rehabilitation, Tendon Injuries surgery
- Abstract
Purpose: The aim of this study was to describe the epidemiology of Achilles tendon re-rupture. Secondary aims were to identify factors predisposing to increased Achilles tendon re-rupture risk, at the time of primary Achilles tendon rupture., Methods: A retrospective review of all patients with primary Achilles tendon rupture and Achilles tendon re-rupture was undertaken. Two separate databases were compiled: the first included all Achilles tendon re-ruptures presenting during the study period and described epidemiology, mechanisms and nature of the re-rupture; the second was a case-control study analysing differences between patients with primary Achilles tendon rupture during the study period, who did, or did not, go on to develop re-rupture, with minimum review period of 1.5 years., Results: Seven hundred and eighty-three patients (567 males, 216 females) attended with primary Achilles tendon rupture and 48 patients (41 males, 7 females) with Achilles tendon re-rupture. Median time to re-rupture was 98.5 days (IQR 82-122.5), but 8/48 re-ruptures occurred late (range 3 to 50 years) after primary Achilles tendon rupture. Males were affected more commonly (OR = 7.40, 95% CI 0.91-60.15; p = 0.034). Mean Achilles tendon re-rupture incidence was 0.94/100,000/year for all ages and 1.16/100,000/year for adults (≥ 18 years). Age distribution was bimodal for both primary Achilles tendon rupture and re-rupture, peaking in the fifth decade, with secondary peaks in older age. Incidence of re-rupture was higher in less socioeconomically deprived sub-populations (OR = 2.01, 95%CI 1.01-3.97, p = 0.04). The majority of re-ruptures were low-energy injuries. Greater risk of re-rupture was noted for patients with primary rupture aged < 45 years [adjusted odds ratio (aOR) 1.96; p = 0.037] and those treated with traditional cast immobilisation (aOR 2.20; p = 0.050)., Conclusion: The epidemiology of Achilles tendon re-rupture is described and known trends (e.g. male predilection) are confirmed, while other novel findings are described, including incidence of a small but significant number of late re-ruptures, occurring years after the primary injury and an increased incidence of re-rupture in less socioeconomically deprived patients. Younger age and traditional immobilising cast treatment of primary Achilles tendon rupture were independently associated with Achilles tendon re-rupture., Level of Evidence: III., (© 2021. The Author(s) under exclusive licence to European Society of Sports Traumatology, Knee Surgery, Arthroscopy (ESSKA).)
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- 2022
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9. Do the outcomes of hip arthroscopy for femoroacetabular impingement change over time?
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Robinson PG, Lu H, Williamson T, Maempel JF, Murray I, MacDonald DJ, Hamilton DF, and Gaston P
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- Arthroscopy, Follow-Up Studies, Hip Joint surgery, Humans, Reoperation, Treatment Outcome, Arthroplasty, Replacement, Hip, Femoracetabular Impingement diagnosis, Femoracetabular Impingement surgery
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Background: The purpose of this study was to search for changes in functional outcomes of patients undergoing hip arthroscopy for femoroacetabular impingement (FAI) between short and medium-term follow-up. Secondary aims included reporting rates of revision surgery and total hip arthroplasty (THA) at medium-term follow-up., Hypothesis: We hypothesised that patients' functional outcomes would improve between short and medium-term follow-up., Patients and Methods: Consecutive patients undergoing hip arthroscopy with a diagnosis of femoroacetabular impingement with labral tears between February 2013 and June 2015 were included. Twelve item international hip outcome tool (iHOT-12) and EuroQol 5D-5L (EQ-5D) scores were collected preoperatively, at short-term and medium-term follow-up. Short-term scores were recorded at a minimum of one year postoperatively and medium-term scores at a minimum of five years postoperatively. Survivorship was assessed with Kaplan-Meier analysis., Results: Short-term outcome data (at median follow-up 1.6 year, Interquartile range [IQR] 1-2.5) was available for 70 of 87 patients (80.5%) and medium-term outcome data (at median follow-up of 6.5 years, IQR 6-7.1) was available for 68 patients (78.2%). Median age at the time of surgery was 31 years (IQR 25-37). The median iHOT-12 scores at short and medium-term follow-up were 72 (IQR 48.75-91.25) and 85.8 (IQR 66.7-96.7) respectively (p<0.001). Medium-term survivorship was 91.2%. Survivorship following labral repair was 94.2%, and 81.3% following labral debridement (p=0.09)., Discussion: Patients undergoing hip arthroscopy for FAI reported continued improvement in iHOT-12 scores between short and medium-term follow-up. Medium-term survivorship following FAI surgery may be greater when the labrum is repaired, although comparisons are limited by their differing indications. Conversion to THA was low with just 4 patients (4.6%) undergoing or being listed for THA at final follow-up., Level of Evidence: IV, Case series., (Copyright © 2021 Elsevier Masson SAS. All rights reserved.)
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- 2022
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10. Pre- and intraoperative decision-making challenges in hip arthroscopy for femoroacetabular impingement.
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Martin H, Robinson PG, Maempel JF, Hamilton D, Gaston P, Safran MR, and Murray IR
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- Arthroscopy methods, Humans, Treatment Outcome, Femoracetabular Impingement surgery
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There has been a marked increase in the number of hip arthroscopies performed over the past 16 years, primarily in the management of femoroacetabular impingement (FAI). Insights into the pathoanatomy of FAI, and high-level evidence supporting the clinical effectiveness of arthroscopy in the management of FAI, have fuelled this trend. Arthroscopic management of labral tears with repair may have superior results compared with debridement, and there is now emerging evidence to support reconstructive options where repair is not possible. In situations where an interportal capsulotomy is performed to facilitate access, data now support closure of the capsule in selective cases where there is an increased risk of postoperative instability. Preoperative planning is an integral component of bony corrective surgery in FAI, and this has evolved to include computer-planned resection. However, the benefit of this remains controversial. Hip instability is now widely accepted, and diagnostic criteria and treatment are becoming increasingly refined. Instability can also be present with FAI or develop as a result of FAI treatment. In this annotation, we outline major current controversies relating to decision-making in hip arthroscopy for FAI. Cite this article: Bone Joint J 2022;104-B(5):532-540.
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- 2022
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11. Age, personal and family history are independently associated with venous thromboembolism following acute Achilles tendon rupture.
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Oliver WM, Mackenzie SA, Lenart L, McCann CJ, Mackenzie SP, Duckworth AD, Clement ND, White TO, and Maempel JF
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- Adult, Humans, Male, Middle Aged, Retrospective Studies, Risk Factors, Achilles Tendon surgery, Pulmonary Embolism, Tendon Injuries, Venous Thromboembolism epidemiology, Venous Thromboembolism etiology
- Abstract
Purpose: The primary aim was to determine independent patient, injury and management-related factors associated with symptomatic venous thromboembolism (VTE) following acute Achilles tendon rupture (ATR). The secondary aim was to suggest a clinical VTE risk assessment tool for patients with acute ATR., Methods: From 2010-2018, 984 consecutive adults (median age 47yrs, 73% [n = 714/984] male) sustaining an acute ATR were retrospectively identified. Ninety-five percent (n = 939/984) were managed non-operatively in a below-knee cast (52%, n = 507/984) or walking boot (44%, n = 432/984), with 5% (n = 45/984) undergoing primary operative repair (<6wks post-injury). VTE was diagnosed using local medical records and national imaging archives, reviewed at a mean 5yrs (range 1-10) post-injury. Multivariate logistic regression was performed to determine independent factors associated with VTE., Results: The incidence of VTE within 90 days of ATR was 3.6% (n = 35/984; deep vein thrombosis 2.1% [n = 21/984], pulmonary embolism 1.9% [n = 19/984]), and the median time to VTE was 24 days (interquartile range 15-44). Age ≥50yrs (adjusted OR [aOR] 2.3, p = 0.027), personal history of VTE/thrombophilia (aOR 6.1, p = 0.009) and family history of VTE (aOR 20.9, p<0.001) were independently associated with VTE following ATR. These non-modifiable risk factors were incorporated into a VTE risk assessment tool. Only 23% of patients developing VTE (n = 8/35) had a relevant personal or family history, but incorporating age ≥50yrs into the VTE risk assessment tool (alongside personal and family history) identified 69% of patients with VTE (n = 24/35). Non weight-bearing for ≥2wks after ATR was also independently associated with VTE (aOR 3.2, p = 0.026)., Conclusions: Age ≥50 years, personal history of VTE/thrombophilia and a positive family history were independently associated with VTE following ATR. Incorporating age into our suggested VTE risk assessment tool enhanced its sensitivity in identifying at-risk patients. Early weight-bearing in an appropriate orthosis may be beneficial to all patients in VTE risk reduction., Competing Interests: Declaration of Competing Interest None., (Copyright © 2021 Elsevier Ltd. All rights reserved.)
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- 2022
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12. Preoperative morbidity and joint awareness while awaiting hip arthroscopy for femoroacetabular impingement.
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Robinson PG, Williamson TR, Murray IR, Maempel JF, MacDonald DJ, Hamilton DF, and Gaston P
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Purpose: The Forgotten Joint Score (FJS-12) is a valid tool in the evaluation of patients undergoing hip arthroscopy, assessing the unique concept of joint awareness in the setting of a patient's hip pathology. The preoperative burden on patients' mental wellbeing of impaired joint function or symptoms is well established. The purpose of this study was to determine patients' awareness of their hip joint whilst awaiting hip arthroscopy for femoroacetabular impingement, to explore any association between joint awareness and mental health status, and to determine whether this relates to time spent waiting for arthroscopy preoperatively., Methods: A prospective database of patients undergoing hip arthroscopy between January 2018 and November 2020 was analysed. All patients with a diagnosis of femoroacetabular impingement (FAI) undergoing arthroscopic treatment were included. Questionnaires included the FJS-12, twelve item international hip outcome tool (iHOT-12), EuroQol 5D-5L (EQ-5D-5L) and the Tegner activity score. Pearson's correlation coefficient was used to assess relationships between continuous variables., Results: Preoperative functional outcomes were completed by 81 patients (97.5%) prior to undergoing hip arthroscopy. Median preoperative FJS-12 score was 16.67 (IQR 8.33 - 29.68). Forty-four patients reported any level of anxiety/depression preoperatively (54.3%). Preoperative FJS-12 showed a significant negative correlation with worsening mental health status (r = - 0.359, p < 0.001), and a significant positive correlation with EQ-5D-5L (r = 0.445, p < 0.001). The duration of symptoms or time on the waiting list did not correlate with increased joint awareness or worsened mental health., Conclusion: Joint awareness is high when awaiting hip arthroscopy for FAI. Increasing levels of joint awareness correlate with poorer mental health status and poorer quality of life measures, however these parameters do not seem to be associated with increased duration of symptoms prior to surgery or time on the waiting list for surgery., (© 2021. The Author(s).)
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- 2021
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13. Defining the Patient Acceptable Symptom State Using the Forgotten Joint Score 12 After Hip Arthroscopy.
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Robinson PG, Gaston P, Williamson TR, Murray IR, Maempel JF, Rankin CS, MacDonald DJ, and Hamilton DF
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Purpose: To contextualize the Forgotten Joint Score (FJS-12) by identifying a patient acceptable symptomatic state (PASS) threshold for patients undergoing hip arthroscopy and to investigate factors which correlated with postoperative FJS-12 score., Methods: All patients who underwent hip arthroscopy for femoroacetabular impingement (FAI) under the care of a single surgeon between January 2018 and November 2019 were prospectively identified and included. Exclusion criteria were Tönnis classification grade 2 or greater. Data (including FJS-12, EuroQol-5 Dimension-5L [EQ-5D-5L], visual analog scale (VAS), and 12-item International Hip Outcome Tool (iHOT-12) scores) were available before surgery and at a minimum of 1 year after surgery. PASS was calculated using an anchor-based approach and receiver operator characteristic curve analysis. Pearson correlation analysis was used to correlate preoperative and postoperative factors with postoperative FJS-12 score., Results: Seventy-seven patients (54 female, 23 male; mean age 30.3 years [standard deviation {SD} 8.2]) were included. Linked longitudinal follow-up data were available for 65 patients (84%) at a mean of 23.8 months (SD 6.4). Six patients required reoperation. Mean postoperative FJS-12 score was 46.5 (SD 33.1) and mean change in score was 27.2 (SD 30.6, P < .001). The PASS threshold for the FJS-12 was 38.5 (sensitivity 80%, specificity 88%), and the area under the curve was 0.852 (95% confidence interval 0.752-0.951). Overall, 53.8% of patients achieved this score. Postoperative FJS-12 score has moderate correlations with preoperative EQ-5D-5L, iHOT-12, and FJS-12 scores, and strong correlations with EQ-5D-5L, iHOT-12 and VAS scores after surgery., Conclusions: We report a postoperative PASS threshold of 38.5 points for the FJS-12 after hip arthroscopy for FAI in a United Kingdom population. This value can act as a quantifiable target for clinicians using the FJS-12 to monitor patient outcomes in practice. FJS-12 has strong correlations with EQ-5D-5L, iHOT-12, and VAS at a minimum 12 months after surgery., Clinical Relevance: We have calculated the patient acceptable symptomatic state of the Forgotten Joint Score to be 38.5 points at short-term follow-up. This can assist clinicians in determining whether surgical interventions related to hip arthroscopy for FAI are meaningful to the patient., (© 2021 by the Arthroscopy Association of North America. Published by Elsevier Inc.)
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- 2021
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14. The forgotten joint score-12 is a valid and responsive outcome tool for measuring success following hip arthroscopy for femoroacetabular impingement syndrome.
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Robinson PG, Rankin CS, Murray IR, Maempel JF, Gaston P, and Hamilton DF
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- Adolescent, Adult, Cohort Studies, Female, Follow-Up Studies, Humans, Male, Middle Aged, Postoperative Period, Prospective Studies, Psychometrics, Range of Motion, Articular, Reproducibility of Results, Statistics, Nonparametric, Surveys and Questionnaires, Treatment Outcome, Young Adult, Arthroscopy methods, Femoracetabular Impingement surgery, Hip Joint surgery, Patient Reported Outcome Measures
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Purpose: The forgotten joint score-12 (FJS-12) is an outcome questionnaire designed to evaluate joint awareness. The responsiveness and validity of the English language version of the FJS-12 in patients undergoing hip arthroscopy for femoroacetabular impingement (FAI) is not known., Methods: Consecutive patients undergoing hip arthroscopy for a diagnosis of FAI were prospectively followed up over a 1 year period. Patients completed preoperative and postoperative FJS-12, EuroQol 5 Dimension (EQ-5D-5L), and the 12-item international hip outcome tool (iHOT-12). We evaluated construct validity with Spearman correlation coefficients for the FJS-12, and responsiveness by way of effect size and ceiling effects., Results: Forty-six patients underwent hip arthroscopy, of which 42 (91%) completed post-operative PROMs at 1 year follow-up. Construct validity was strong with the iHOT-12 (r = 0.87) and also the EQ-5D-5L (r = 0.83). The median postoperative FJS score was 50.2 (IQR 64). The mean change in score for the FJS-12 was 31 points (SD 31) (p < 0.001), with an effect size (Cohen's d) of 1.16. Preoperatively, three patients scored the lowest possible value resulting in a floor effect of 7.1%. Similarly, only three patients (7.1%) scored the best possible score post-operatively., Conclusion: This is the first evaluation of the joint awareness concept in the English language version of the FJS-12 following hip arthroscopy for FAI. The FJS-12 is a valid and responsive tool for the assessment of this cohort of patients., Level of Evidence: II.
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- 2021
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15. Systematic review of randomised controlled trials for interventions to treat injuries to the medial ligaments of the knee.
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Roberts SB, Brown OS, Beattie N, Brown GS, Maempel JF, and White T
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- Humans, Ligaments, Articular surgery, Patient Reported Outcome Measures, Randomized Controlled Trials as Topic, Knee Injuries therapy, Ligaments, Articular injuries
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Background: Optimal management of severe and complex injuries to the medial knee ligaments remains uncertain. This systematic review evaluates outcomes from randomised controlled trials investigating interventions for treating injuries of medial ligaments of the knee., Methods: Randomised controlled clinical trials evaluating interventions for treating injuries of the medial knee ligaments were identified through searching EMBASE, Medline, Cochrane, WHO, and clinicaltrials.org. Comparisons were made between different non-operative interventions, surgical versus non-operative interventions, different surgical interventions, and different postoperative interventions. Primary outcome measures included patient reported outcome measures (PROM) of knee function, pain, and treatment failure., Results: 412 trial records were identified; 259 were non-redundant and distinct studies, of which eight were included for analysis. No differences between operative and non-operative management strategies were found for either primary outcome: Lysholm and IKDC scores. Compared to non-operative interventions, operative interventions resulted in reduced quadriceps strength at eight weeks (mean difference (MD) 29 (% knee extension strength deficit compared with unaffected knee); 95%CI 3.89-54.11) and were associated with greater incidence of minor complications (relative risk (RR) 25; 95%CI: 1.51-421, and RR 25; 95%CI: 1.50-416.58, respectively). Quadriceps strength between 16 and 52 weeks was similar in non-operative and operative groups (MD 20; 95%CI -1.92-41.92). Functional rehabilitation was associated with reduced valgus laxity at six weeks compared to bracing ((MD) -1.40; 95%CI: -2.21-0.59)., Conclusions: Non-operative interventions provided similar functional results to operative interventions for grade I-III injuries of the medial collateral ligaments. Non-operative intervention was associated with improved quadriceps strength during rehabilitation, and fewer complications, compared to operative interventions., Competing Interests: Declaration of Competing Interest None., (Copyright © 2020 Royal College of Surgeons of Edinburgh (Scottish charity number SC005317) and Royal College of Surgeons in Ireland. Published by Elsevier Ltd. All rights reserved.)
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- 2021
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16. A Randomized Controlled Trial Comparing Traditional Plaster Cast Rehabilitation With Functional Walking Boot Rehabilitation for Acute Achilles Tendon Ruptures.
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Maempel JF, Clement ND, Duckworth AD, Keenan OJF, White TO, and Biant LC
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- Adult, Humans, Middle Aged, Rupture, Treatment Outcome, Walking, Achilles Tendon injuries, Casts, Surgical, Tendon Injuries
- Abstract
Background: There has been a shift toward functional nonoperative rehabilitation in the treatment of Achilles tendon rupture (ATR) despite a shortage of studies directly comparing nonoperative functional rehabilitation with traditional nonoperative immobilization., Purpose: To compare patient-reported outcome measures and functional outcomes for nonoperatively treated ATR with traditional cast immobilization or functional rehabilitation in a walking boot., Study Design: Randomized controlled clinical trial; Level of evidence, 2., Methods: In a single-center nonblinded study, 140 patients were randomized to compare treatment for acute ATR in (1) an immobilizing cast in reducing degrees of equinus over a 10-week period with 8 weeks of nonweightbearing mobilization or (2) a walking boot for 8 weeks with reducing equinus and immediate full weightbearing. Exclusion criteria were delayed presentation >2 weeks after injury, tendon reruptures, and latex allergy. Analysis was undertaken on an intention-to-treat basis., Results: A total of 69 patients (median age, 41 years [interquartile range, 33-50.5 years]) were randomized to walking boot treatment and 71 patients (41 [32-49]) to cast treatment. At 6 months, patients treated in a walking boot reported better Short Musculoskeletal Function Assessment (SMFA) dysfunction index (6.62 [2.21-12.50] vs 10.66 [4.96-13.42]; P = .050), SMFA bother index (7.29 [2.08-14.58] vs 10.42 [5.73-19.27]; P = .04), Achilles Tendon Total Rupture Score (71.5 [53.50-84.25] vs 54.0 [37-76]; P = .01), and Foot and Ankle Questionnaire core score (91 [81.89-97.55] vs 85 [78.25-92.09]; P = .04). At 1 year, there was no difference in SMFA dysfunction index (2.21 [0.74-5.88] vs 2.94 [1.47-6.62]; P = .25), SMFA bother index (2.08 [0-9.38] vs 5.21 [0.52-11.98]; P = .25), Achilles Tendon Total Rupture Score (92 [72.50-96] vs 87.5 [66.0-94.75]; P = .21), or Foot and Ankle Questionnaire core score (97.75 [89.46-99.00] vs 95.50 [90.88-97.50]; P = .18). Rerupture occurred in 5 and 11 patients ( P = .075) and venous thromboembolism in 2 and 3 patients ( P = .67) in the boot and cast groups, respectively. Fifteen patients in the boot group but none in the cast group had skin problems ( P < .001). Patients treated in a boot returned to driving at a median 12 weeks (vs 13 weeks for cast; P = .045), but there was no difference in time to return to work ( P = .48)., Conclusion: Functional rehabilitation with early weightbearing is a safe alternative to traditional immobilizing treatment for ATR, giving better early functional outcomes, albeit with a higher incidence of transient minor skin complications., Registration: NCT02598843 (ClinicalTrials.gov identifier).
- Published
- 2020
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17. Responsiveness and ceiling effects of the English version of the 12-item International Hip Outcome Tool following hip arthroscopy at minimum one-year follow-up.
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Robinson PG, Maempel JF, Murray IR, Rankin CS, Hamilton DF, and Gaston P
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- Adult, Cohort Studies, Female, Femoracetabular Impingement surgery, Follow-Up Studies, Hip Joint surgery, Humans, Male, Middle Aged, Minimal Clinically Important Difference, Postoperative Care methods, Preoperative Care methods, Retrospective Studies, Severity of Illness Index, Time Factors, Treatment Outcome, Weights and Measures, Arthroscopy methods, Femoracetabular Impingement diagnosis, Pain Measurement, Patient Reported Outcome Measures, Range of Motion, Articular physiology
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Aims: Responsiveness and ceiling effects are key properties of an outcome score. No such data have been reported for the original English version of the International Hip Outcome Tool 12 (iHOT-12) at a follow-up of more than four months. The aim of this study was to identify the responsiveness and ceiling effects of the English version iHOT-12 in a series of patients undergoing hip arthroscopy for intra-articular hip pathology at a minimum of one year postoperatively., Methods: A total of 171 consecutive patients undergoing hip arthroscopy with a diagnosis of femoroacetabular impingement (FAI) under the care of a single surgeon between January 2013 and March 2017 were included. iHOT-12 and EuroQol 5D-5L (EQ-5D-5L) scores were available pre- and postoperatively. Effect size and ceiling effects for the iHOT-12 were calculated with subgroup analysis., Results: A total of 122 patients (71.3%) completed postoperative PROMs scores with median follow-up of 24.3 months (interquartile range (IQR) 17.2 to 33.5). The median total cohort iHOT-12 score improved significantly from 31.0 (IQR 20 to 58) preoperatively to 72.5 (IQR 47 to 90) postoperatively (p < 0.001). The effect size (Cohen's d) was 1.59. In all, 33 patients (27%) scored within ten points (10%) of the maximum score and 38 patients (31.1%) scored within the previously reported minimal clinically important difference (MCID) of the maximum score. Furthermore, nine (47%) male patients aged < 30 years scored within 10% of the maximum score and ten (53%) scored within the previously reported MCID of the maximum score., Conclusion: There is a previously unreported ceiling effect of the iHOT-12 at a minimum one-year follow-up which is particularly marked in young, male patients following hip arthroscopy for FAI. This tool may not have the maximum measurement required to capture the true outcome following this procedure. Cite this article: Bone Joint J 2020;102-B(8):1010-1015.
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- 2020
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18. Operative repair of acute Achilles tendon rupture does not give superior patient-reported outcomes to nonoperative management.
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Maempel JF, Clement ND, Wickramasinghe NR, Duckworth AD, and Keating JF
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- Adult, Female, Humans, Male, Middle Aged, Recovery of Function, Rupture, Tendon Injuries surgery, Achilles Tendon injuries, Patient Reported Outcome Measures, Tendon Injuries therapy
- Abstract
Aims: The aim was to compare long-term patient-reported outcome measures (PROMs) after operative and nonoperative treatment of acute Achilles tendon rupture in the context of a randomized controlled trial., Methods: PROMs including the Short Musculoskeletal Function Assessment (SMFA), Achilles Tendon Total Rupture Score (ATRS), EuroQol five-dimension (EQ-5D), satisfaction, net promoter score and data regarding re-rupture, and venous thromboembolic rates were collected for patients randomized to receive either operative or nonoperative treatment for acute Achilles tendon rupture in a previous study. Of the 80 patients originally randomized, 64 (33 treated surgically, 31 nonoperatively) patients were followed up at a mean of 15.7 years (13.4 to 17.7)., Results: There was no statistically significant difference between operatively and nonoperatively treated patients, in SMFA Dysfunction Index (median 1.56 (interquartile range (IQR) 0 to 5.51) vs 1.47 (IQR 0 to 5.15); p = 0.289), SMFA Bother Index (2.08 (IQR 0 to 12.50) vs 0.00 (IQR 0 to 6.25); p = 0.074), ATRS (94 (IQR 86 to 100) vs 95 (IQR 81 to 100); p = 0.313), EQ-5D-5L (1 (IQR 0.75 to 1) vs 1 (IQR 0.84 to 1); p = 0.137) or EQ-5D health today visual analogue score (85 (IQR 72.5 to 95) vs 85 (IQR 8 to 95); p = 0.367). There was no statistically significant difference between operative and nonoperative groups in terms of satisfaction (84% vs 100%; p = 0.119) or willingness to recommend treatment to friends or family (79% vs 87%; p = 0.255). Four nonoperative patients and two in the operative group sustained a re-rupture (p = 0.306)., Conclusion: Both patient groups reported good results at long-term follow-up. The findings give no evidence of superior long-term patient reported outcomes (as measured by the SMFA) for surgical treatment over nonoperative treatment. There was no demonstrable difference in other patient reported outcome measures, satisfaction, or re-rupture rates at long-term follow-up. Cite this article: Bone Joint J 2020;102-B(7):933-940.
- Published
- 2020
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19. Correlations between radiological classification systems and confirmed cartilage loss in severe knee osteoarthritis.
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Keenan OJF, Holland G, Maempel JF, Keating JF, and Scott CEH
- Subjects
- Adult, Aged, Aged, 80 and over, Arthroplasty, Replacement, Knee, Female, Follow-Up Studies, Humans, Knee Joint surgery, Male, Middle Aged, Osteoarthritis, Knee diagnosis, Osteoarthritis, Knee surgery, Prospective Studies, ROC Curve, Reproducibility of Results, Severity of Illness Index, Cartilage, Articular diagnostic imaging, Knee Joint diagnostic imaging, Osteoarthritis, Knee classification, Radiography methods
- Abstract
Aims: Although knee osteoarthritis (OA) is diagnosed and monitored radiologically, actual full-thickness cartilage loss (FTCL) has rarely been correlated with radiological classification. This study aims to analyze which classification system correlates best with FTCL and to assess their reliability., Methods: A prospective study of 300 consecutive patients undergoing unilateral total knee arthroplasty (TKA) for OA (mean age 69 years (44 to 91; standard deviation (SD) 9.5), 178 (59%) female). Two blinded examiners independently graded preoperative radiographs using five common systems: Kellgren-Lawrence (KL); International Knee Documentation Committee (IKDC); Fairbank; Brandt; and Ahlbäck. Interobserver agreement was assessed using the intraclass correlation coefficient (ICC). Intraoperatively, anterior cruciate ligament (ACL) status and the presence of FTCL in 16 regions of interest were recorded. Radiological classification and FTCL were correlated using the Spearman correlation coefficient., Results: Knees had a mean of 6.8 regions of FTCL (SD 3.1), most common medially. The commonest patterns of FTCL were medial ± patellofemoral (143/300, 48%) and tricompartmental (89/300, 30%). ACL status was associated with pattern of FTCL (p = 0.023). All radiological classification systems demonstrated moderate ICC, but this was highest for the IKDC: whole knee 0.68 (95% confidence interval (CI) 0.60 to 0.74); medial compartment 0.84 (95% CI 0.80 to 0.87); and lateral compartment 0.79 (95% CI 0.73 to 0.83). Correlation with actual FTCL was strongest for Ahlbäck (Spearman rho 0.27 to 0.39) and KL (0.30 to 0.33) systems, although all systems demonstrated medium correlation. The Ahlbäck score was the most discriminating in severe knee OA. Osteophyte presence in the medial compartment had high positive predictive value (PPV) for FTCL, but not in the lateral compartment., Conclusion: The Ahlbäck and KL systems had the highest correlation with confirmed cartilage loss at TKA. However, the IKDC system displayed the best interobserver reliability, with favourable correlation with FTCL in medial and lateral compartments, although it was less discriminating in more severe disease. Cite this article: Bone Joint J 2020;102-B(3):301-309.
- Published
- 2020
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20. The relationship of mental health status to functional outcome and satisfaction after carpal tunnel release.
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Maempel JF, Jenkins PJ, and McEachan JE
- Subjects
- Disability Evaluation, Hand, Health Status, Humans, Patient Satisfaction, Surveys and Questionnaires, Treatment Outcome, Carpal Tunnel Syndrome surgery, Personal Satisfaction
- Abstract
We studied whether mental health status is significantly correlated to patient reported functional outcomes and satisfaction after carpal tunnel release. Over a 7-year period, 809 patients completed Short Form-12 (SF-12) questionnaires which allowed calculation of the SF-12 mental component summary 1 year postoperatively, 780 (96%) completed a satisfaction questionnaire and 777 (96%) completed a QuickDisabilities of the Arm, Shoulder, and Hand (DASH) questionnaire. Median QuickDASH score was 55 preoperatively (interquartile range [IQR] 28) and 14 postoperatively (IQR 32). A total of 674 patients were satisfied. Patients with mental disability had worse QuickDASH scores (median 34, IQR 41) and a higher incidence of dissatisfaction (52/245, 21%) than those without mental disability (n = 9, IQR 20, 10%, both p < 0.001). Regression analyses indicated scores in the SF-12 mental component summary were significantly related to postoperative QuickDASH score ( p < 0.001) and satisfaction ( p = 0.02). We concluded that patients with mental disability report poorer outcomes and lower satisfaction rates; however, the majority still exhibit significant improvements and are satisfied. Level of evidence: II.
- Published
- 2020
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21. Evaluation of the patient acceptable symptom state following hip arthroscopy using the 12 item international hip outcome tool.
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Robinson PG, Maempel JF, Rankin CS, Gaston P, and Hamilton DF
- Subjects
- Adolescent, Adult, Databases, Factual, Female, Femoracetabular Impingement diagnostic imaging, Femoracetabular Impingement physiopathology, Hip Joint diagnostic imaging, Hip Joint physiopathology, Humans, Male, Psychometrics, Quality of Life, Recovery of Function, Reproducibility of Results, Retrospective Studies, Time Factors, Treatment Outcome, United Kingdom, Young Adult, Arthroscopy adverse effects, Femoracetabular Impingement surgery, Hip Joint surgery, Patient Reported Outcome Measures, Patient Satisfaction
- Abstract
Background: The International Hip Outcome Tool 12 (iHOT-12) is a shorter version of the iHOT-33 which measures health related quality of life following treatment of hip disorders in young, active patients. The purpose of this study was identify a PASS threshold for a UK population undergoing hip arthroscopy for intra-articular hip pathology., Methods: Data was identified retrospectively from a prospective database of patients undergoing hip arthroscopy under the care of a single surgeon within the date range January 2013 to March 2017. All patients with a diagnosis of femoroacetabular impingment (FAI) undergoing arthroscopic treatment were included. iHOT-12, EuroQol 5D-5 L (EQ-5D-5 L) and a satisfaction questionnaire were available pre and post-operatively. PASS was calculated using an anchor-based approach and receiver operator characteristic (ROC) analysis., Results: 171 patients underwent hip arthroscopy in the study period. Linked longitudinal follow-up data was available for 122 patients (71.3%) at a median of 24.3 months (740 days, interquartile range 576-1047). The PASS threshold for the iHOT-12 was 59.5 (sensitivity 81.1%, specificity 83.9%; area under the curve (AUC) 0.92, 95% CI 0.87-0.97). 64% of patients achieved this score. The median postoperative iHOT-12 score was 72.5 (IQR 44) and the mean change in score was 35 (SD 25, p < 0.001). The EQ-5D Index improved by 0.18 (SD 0.25, p < 0.001) and there was a mean change of 7.67 (SD 24.82) on the EQ-5D VAS (p = 0.001)., Conclusions: We report a PASS threshold of the iHOT-12 following hip arthroscopy for FAI as a measurable benchmark for clinicians using this outcome measure.
- Published
- 2020
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22. Non-invasive massive growing prostheses reduce infection in paediatric cancer patients.
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Coathup MJ, Ahmad S, Maempel JF, Briggs TW, Aston WJ, Skinner JA, and Blunn GW
- Subjects
- Adolescent, Child, Child, Preschool, Female, Humans, Infant, Male, Prosthesis Implantation adverse effects, Prosthesis-Related Infections epidemiology, Plastic Surgery Procedures adverse effects, Survival Analysis, Treatment Outcome, Bone Neoplasms surgery, Prostheses and Implants adverse effects, Prosthesis Implantation instrumentation, Prosthesis-Related Infections prevention & control, Plastic Surgery Procedures instrumentation, Sarcoma surgery
- Abstract
Purpose: In this study, we asked the question of whether non-invasive (NI) extendible bone tumour implants are as reliable and reduce infection when compared with patients who received a minimally invasive (MI) extendible implant., Methods: Forty-two NI extendible bone tumour implants were investigated at a mean follow-up of 22 months (range, 1-87 months) and 63 MI implants at a mean follow-up of 49 months (range, 1-156 months)., Results: Kaplan-Meier analysis showed that the probability of MI implant survival was 58.8% compared with 78.6% in NI patients. No significant difference between these two patient groups was found. Infection was the main reason for failure in the MI implant group where nine (35%) implants were revised. However, only one (11%) NI implant was revised for infection ( p = 0.042). None of the NI implants failed due to aseptic loosening; however, six (23%) MI implants were revised for aseptic loosening of the intramedullary stem. Four (15%) of the failed MI implants were revised due to full extension and five (56%) of failed NI implants were replaced as the implant had been fully extended where the patient still required growth., Conclusion: Where possible, an NI massive prosthesis should be used in this patient group. Our results suggest that MI prostheses should be infrequently used due to the high incidence of infection. Lengthening of NI prostheses is painless, can be carried out in the clinic and is more cost-effective. However, further work is required to increase the amount of growth potential available in these implants.
- Published
- 2019
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23. Assessing the Outcome of Hip Arthroscopy for Labral Tears in Femoroacetabular Impingement Using the Minimum Dataset of the British Non-arthroplasty Hip Register: A Single-Surgeon Experience.
- Author
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Maempel JF, Ting JZ, and Gaston P
- Subjects
- Adolescent, Adult, Arthroscopy, Female, Humans, Interviews as Topic, Male, Middle Aged, Postoperative Period, Registries, State Medicine, Surveys and Questionnaires, United Kingdom, Visual Analog Scale, Young Adult, Femoracetabular Impingement surgery, Patient Reported Outcome Measures, Patient Satisfaction, Quality of Life
- Abstract
Purpose: The aim of this study was to assess changes in British Non-arthroplasty Hip Register (NAHR) minimum dataset (MDS) patient-reported outcome measures (PROMs) after hip arthroscopy for femoroacetabular impingement (FAI) and define the relation between these and patient satisfaction. Secondary aims included exploring the impact of patient characteristics (age, sex, and social deprivation status) on MDS PROMs and satisfaction and determining the Net Promoter Score for hip arthroscopy for FAI., Methods: Preoperative data were collected from the NAHR, and postoperative data were collected through the NAHR, by mail, and by telephone survey. Correlations between satisfaction, International Hip Outcome Tool 12 (iHOT-12), and EQ-5D scores were explored., Results: A consecutive series of 89 primary hip arthroscopy procedures for FAI in 88 patients is reported. Patients reported improvements in the iHOT-12 score (mean, 34.08; 95% confidence interval [CI], 27.88 to 40.28; P < .001), EQ-5D index score (+0.124; 95% CI, 0.063 to 0.185; P < .001), and EQ-5D visual analog scale (VAS) (+4.49; 95% CI, -1.56 to 10.54; P = .061) after hip arthroscopy for FAI. Satisfaction was predicted by both change in iHOT-12 score (Spearman r [r
s ] = 0.54, P < .001) and absolute postoperative iHOT-12 score (rs = 0.78, P < .001), change in EQ-5D index score (rs = 0.42, P < .001) and absolute postoperative EQ-5D index score (rs = 0.70, P < .001), and change in EQ-5D VAS score (rs = 0.30, P = .012) and absolute postoperative EQ-5D VAS score (rs = 0.59, P < .001); and the strength of correlation was greater with the absolute postoperative score than with the change in score for all 3. Sex, age, and social deprivation status did not predict postoperative PROMs (P ≥ .15) or satisfaction (P ≥ .32). The postoperative iHOT-12 score correlated strongly with EQ-5D index (rs = 0.90, P < .001) and EQ-5D VAS (rs = 0.81, P < .001) scores. The Net Promoter Score for hip arthroscopy for FAI was 70.31., Conclusions: This study showed significant improvements in hip-specific function (iHOT-12) and health-related quality of life (EQ-5D), as measured by the NAHR MDS, in patients undergoing hip arthroscopy for FAI. Satisfaction rates were high (75.7%) and correlated strongly with hip-specific and general health PROMs. Satisfied patients were more likely to be willing to undergo similar surgery in the future. Self-reported postoperative hip function correlated very strongly with general health-related quality of life., Level of Evidence: Level IV, case series., (Copyright © 2018 Arthroscopy Association of North America. Published by Elsevier Inc. All rights reserved.)- Published
- 2018
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24. Correction to: Tram system related cycling injuries.
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Maempel JF, Mackenzie SP, Stirling PHC, McCann C, Oliver CW, and White TO
- Abstract
The author would like to correct the errors in the publication of the original article. The corrected details are given below for your reading.
- Published
- 2018
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25. Tram system related cycling injuries.
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Maempel JF, Mackenzie SP, Stirling PHC, McCann C, Oliver CW, and White TO
- Subjects
- Adult, Female, Fractures, Bone epidemiology, Humans, Male, Middle Aged, Retrospective Studies, Scotland, Transportation, Young Adult, Accidents, Traffic statistics & numerical data, Bicycling
- Abstract
Introduction: Understanding of tram-system related cycling injuries (TSRCI) is poor. The aim of this study was to report the spectrum of injuries, demographics and social deprivation status of patients. Secondary aims included assessment of accident circumstances, effects of TSRCI on patients' confidence cycling, together with time off work and cycling., Methods: A retrospective review of patients presenting to emergency services across all hospitals in Edinburgh and West Lothian with tram related injuries between May 2009 and April 2016 was undertaken. Medical records and imagining were analysed and patients were contacted by telephone., Results: 191 cyclists (119 males, 72 females) were identified. 63 patients sustained one or more fractures or dislocations. Upper limb fractures/dislocations occurred in 55, lower limb fractures in 8 and facial fractures in 2. Most patients demonstrated low levels of socioeconomic deprivation. In 142 cases, the wheel was caught in tram-tracks, while in 32 it slid on tracks. The latter occurred more commonly in wet conditions (p = 0.028). 151 patients answered detailed questionnaires. Ninety-eight were commuting. 112 patients intended to cross tramlines and 65 accidents occurred at a junction. Eighty patients reported traffic pressures contributed to their accident. 120 stated that their confidence was affected and 24 did not resume cycling. Female gender (p < 0.001) and presence of a fracture/dislocation (p = 0.012) were independent predictors of negative effects on confidence. Patients sustaining a fracture/dislocation spent more time off work (median 5 days vs 1, p < 0.001) and cycling (median 57 days vs 21, p < 0.001)., Conclusions: TSRCI occur predominantly in young to middle-aged adults with low levels of socioeconomic deprivation, most commonly when bicycle wheels get caught in tram-tracks. They result in various injuries, frequently affecting the upper limb. Traffic pressures are commonly implicated. Most patients report negative effects on confidence and a sizeable minority do not resume cycling. TSRCI can result in significant loss of working and cycling days.
- Published
- 2018
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26. Range of movement correlates with the Oxford knee score after total knee replacement: A prediction model and validation.
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Maempel JF, Clement ND, Brenkel IJ, and Walmsley PJ
- Subjects
- Humans, Models, Theoretical, Prognosis, Range of Motion, Articular, Reproducibility of Results, Treatment Outcome, Arthroplasty, Replacement, Knee, Health Status Indicators, Osteoarthritis, Knee surgery, Patient Reported Outcome Measures
- Abstract
Background: Patient reported outcome measures are widely used in the evaluation of outcomes after Total Knee Replacement (TKR) in joint registries and large studies. The aim of this study was to assess the relationship between the Oxford knee score (OKS) and range of motion (ROM) after TKR, and to construct and validate prediction models of ROM from the measured OKS., Methods: Eight hundred sixty patients reviewed five years postoperatively and 273 patients reviewed nine to 10 years postoperatively completed an OKS. Of these, 808 (94%) and 226 (83%) patients, respectively, had a complete dataset (knee extension and ROM) and formed the study cohort., Results: Regression analysis demonstrated a significant correlation between the OKS and ROM (r=0.38, p<0.001) after adjusting for other confounding variables (age, sex, body mass index, and knee extension). A prediction model was constructed and validated using a second cohort of 226 patients at nine to 10 years after their TKR. Intraclass correlation demonstrated good reliability (r=0.60, 95% CI 0.47 to 0.69) between predicted and actual measured ROM for this group. However, when the OKS is used in isolation the reliability of the predicted ROM is diminished (intraclass correlation r=0.41, 95% CI 0.24 to 0.55)., Conclusions: The OKS is an independent predictor of ROM after TKR. It is also possible to predict ROM from the OKS, but the reliability of this is improved when other independent predictors such as age, gender, body mass index (BMI) and degree of knee extension are also acknowledged., (Copyright © 2016 Elsevier B.V. All rights reserved.)
- Published
- 2016
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27. Enhanced recovery programmes after total hip arthroplasty can result in reduced length of hospital stay without compromising functional outcome.
- Author
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Maempel JF, Clement ND, Ballantyne JA, and Dunstan E
- Subjects
- Aged, Female, Follow-Up Studies, Hip Joint surgery, Humans, Male, Middle Aged, Retrospective Studies, Treatment Outcome, Arthroplasty, Replacement, Hip rehabilitation, Hip Joint physiopathology, Length of Stay trends, Postoperative Care methods, Range of Motion, Articular physiology, Recovery of Function
- Abstract
Aims: The primary aim of this study was to investigate the effect of an enhanced recovery program (ERP) on the short-term functional outcome after total hip arthroplasty (THA). Secondary outcomes included its effect on rates of dislocation and mortality., Patients and Methods: Data were gathered on 1161 patients undergoing primary THA which included 611 patients treated with traditional rehabilitation and 550 treated with an ERP., Results: The ERP was shown to be a significant independent factor which shortened length of stay (LOS) by a mean of 1.5 days (95% confidence interval (CI) 1.3 to 1.8, p < 0.001) after adjusting for confounding variables. The rates of dislocation (traditional 1.03% vs ERP 0.91%, p = 0.84) and mortality (1.5% vs 0.6%, p = 0.14) one year post-operatively were not significantly different. Both groups showed significant improvement in Harris Hip Score (42.8 vs 41.5) at 12 to 18 months post-operatively and there was no significant difference in the magnitude of improvement on univariate (p = 0.09) and multivariate analysis (p = 0.35). There was no significant difference in any of the eight domain scores of the Short-Form - 36 general health surveys post-operatively (p > 0.38)., Conclusion: We conclude that an ERP after THA shortens LOS by a mean of 1.5 days and does not increase the rate of complications post-operatively. It gives equivalent functional outcomes to a traditional rehabilitation pathway., Take Home Message: ERP reduces LOS after THA in comparison to traditional rehabilitation, without adversely affecting functional outcomes, dislocation rates or mortality., (©2016 The British Editorial Society of Bone & Joint Surgery.)
- Published
- 2016
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28. The pre-operative levels of haemoglobin in the blood can be used to predict the risk of allogenic blood transfusion after total knee arthroplasty.
- Author
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Maempel JF, Wickramasinghe NR, Clement ND, Brenkel IJ, and Walmsley PJ
- Subjects
- Aged, Female, Humans, Incidence, Male, Middle Aged, Odds Ratio, Postoperative Complications blood, Postoperative Period, Predictive Value of Tests, Preoperative Period, ROC Curve, Retrospective Studies, United Kingdom epidemiology, Arthroplasty, Replacement, Knee, Blood Transfusion, Autologous statistics & numerical data, Hemoglobins metabolism, Postoperative Complications epidemiology
- Abstract
Aims: The pre-operative level of haemoglobin is the strongest predictor of the peri-operative requirement for blood transfusion after total knee arthroplasty (TKA). There are, however, no studies reporting a value that could be considered to be appropriate pre-operatively. This study aimed to identify threshold pre-operative levels of haemoglobin that would predict the requirement for blood transfusion in patients who undergo TKA., Patients and Methods: Analysis of receiver operator characteristic (ROC) curves of 2284 consecutive patients undergoing unilateral TKA was used to determine gender specific thresholds predicting peri-operative transfusion with the highest combined sensitivity and specificity (area under ROC curve 0.79 for males; 0.78 for females)., Results: Threshold levels of 13.75 g/dl for males and 12.75 g/dl for females were identified. The rates of transfusion in males and females, respectively above these levels were 3.37% and 7.11%, while below these levels, they were 16.13% and 28.17%. Pre-operative anaemia increased the rate of transfusion by 6.38 times in males and 6.27 times in females. Blood transfusion was associated with an increased incidence of early post-operative confusion (odds ratio (OR) = 3.44), cardiac arrhythmia (OR = 5.90), urinary catheterisation (OR = 1.60), the incidence of deep infection (OR = 4.03) and mortality (OR = 2.35) one year post-operatively, and increased length of stay (eight days vs six days, p < 0.001)., Conclusion: Uncorrected low pre-operative levels of haemoglobin put patients at potentially modifiable risk and attempts should be made to correct this before TKA. Target thresholds for the levels of haemoglobin pre-operatively in males and females are proposed., Take Home Message: Low pre-operative haemoglobin levels put patients at unnecessary risk and should be corrected prior to surgery., (©2016 The British Editorial Society of Bone & Joint Surgery.)
- Published
- 2016
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29. Validation of a prediction model that allows direct comparison of the Oxford Knee Score and American Knee Society clinical rating system.
- Author
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Maempel JF, Clement ND, Brenkel IJ, and Walmsley PJ
- Subjects
- Aged, Aged, 80 and over, Female, Follow-Up Studies, Health Status Indicators, Humans, Male, Models, Theoretical, Prospective Studies, Reproducibility of Results, Treatment Outcome, Arthroplasty, Replacement, Knee, Knee surgery, Knee Joint surgery, Osteoarthritis, Knee surgery
- Abstract
This study demonstrates a significant correlation between the American Knee Society (AKS) Clinical Rating System and the Oxford Knee Score (OKS) and provides a validated prediction tool to estimate score conversion. A total of 1022 patients were prospectively clinically assessed five years after TKR and completed AKS assessments and an OKS questionnaire. Multivariate regression analysis demonstrated significant correlations between OKS and the AKS knee and function scores but a stronger correlation (r = 0.68, p < 0.001) when using the sum of the AKS knee and function scores. Addition of body mass index and age (other statistically significant predictors of OKS) to the algorithm did not significantly increase the predictive value. The simple regression model was used to predict the OKS in a group of 236 patients who were clinically assessed nine to ten years after TKR using the AKS system. The predicted OKS was compared with actual OKS in the second group. Intra-class correlation demonstrated excellent reliability (r = 0.81, 95% confidence intervals 0.75 to 0.85) for the combined knee and function score when used to predict OKS. Our findings will facilitate comparison of outcome data from studies and registries using either the OKS or the AKS scores and may also be of value for those undertaking meta-analyses and systematic reviews., (©2015 The British Editorial Society of Bone & Joint Surgery.)
- Published
- 2015
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30. Longer hospital stay, more complications, and increased mortality but substantially improved function after knee replacement in older patients.
- Author
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Maempel JF, Riddoch F, Calleja N, and Brenkel IJ
- Subjects
- Adult, Age Factors, Aged, Aged, 80 and over, Female, Humans, Incidence, Male, Middle Aged, Prospective Studies, Prosthesis-Related Infections epidemiology, Prosthesis-Related Infections mortality, Reoperation statistics & numerical data, Retrospective Studies, Survival Rate, Treatment Outcome, Venous Thromboembolism epidemiology, Venous Thromboembolism mortality, Arthroplasty, Replacement, Knee, Knee Joint physiology, Knee Prosthesis microbiology, Length of Stay statistics & numerical data, Postoperative Complications epidemiology, Postoperative Complications mortality, Range of Motion, Articular physiology
- Abstract
Background and Purpose: Total knee replacement (TKR) is being increasingly performed in elderly patients, yet there is little information on specific requirements and complication rates encountered by this group. We assessed whether elderly patients undergoing TKR had different length of stay, requirements, complication rates, and functional outcomes compared to younger counterparts., Patients and Methods: We analyzed prospectively gathered data on 3,144 consecutive primary TKRs (in 2,092 patients aged less than 75 years, 694 patients aged between 75 and 80 years, and 358 patients aged over 80 years at the time of surgery)., Results: Incidence of blood transfusion, urinary catheterization, postoperative confusion, cardiac arrhythmia, and 1-year mortality increased with age, even after adjusting for confounding factors, whereas the incidences of chest infection and mortality at 1 month were highest in those aged 75-80. Rates of thromboembolism, prosthetic infection, and revision were similar in the 3 age groups. All groups showed similar substantial improvements in American Knee Society (AKS) knee scores, which were maintained at 5 years. Older patients had smaller improvements in AKS function score, which deteriorated between 3 and 5 years postoperatively, in contrast to the younger group., Interpretation: Elderly people stand to gain considerably from TKR, particularly in terms of pain relief, and they should not be denied surgery based solely on age. However, they should be warned that they can expect a longer length of stay, a higher requirement for blood transfusion and/or urinary catheterization, and more medical complications postoperatively. Mortality was also higher in the older age groups. The risks have been quantified to assist in perioperative counselling, informed consent, and healthcare planning.
- Published
- 2015
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31. A foreign body masquerading as a tumour.
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Maempel JF, Nicol G, Clement RG, and Porter D
- Subjects
- Adult, Diagnosis, Differential, Foreign Bodies surgery, Humans, Magnetic Resonance Imaging, Male, Tomography, X-Ray Computed, Foreign Bodies diagnosis, Muscle Neoplasms diagnosis, Thigh
- Abstract
A 29-year-old man presented to his local orthopaedic service with a mass in the medial aspect of his left thigh, present for 1 year. It had not changed in size, although he complained of increasing tightness in the region. He denied any systemic symptoms or history of local trauma. Extensive imaging performed at his local hospital was thought suggestive of a musculoskeletal tumour. The patient was referred to our tertiary centre musculoskeletal tumour clinic. Review of external imaging and further investigations revealed a fluid-filled intramuscular mass containing an echogenic focus consistent with foreign body. Ultrasound-guided aspiration yielded fluid which grew Staphylococcus aureus. Only when presented with this information did the patient vaguely recall sitting on a wooden kebab stick 30 months previously. At surgery, a thick-walled abscess with a central foreign body was identified and drained. At follow-up 1 month later, he was well with no recurrent problems.
- Published
- 2013
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32. Olanzapine and pulmonary embolism, a rare association: a case report.
- Author
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Maempel JF, Darmanin G, Naeem K, and Patel M
- Abstract
Venous thromboembolism is a very common pathological process for which there are many well known (and less well-known) predisposing factors. Likewise, olanzapine is a commonly used anti-psychotic medication.We present the case of a young Somali gentleman who developed venous thromboembolic disease after an overdose of olanzapine. The diagnosis was only made 48 hours after admission, due to the non-specific presentation of the pulmonary embolus and the fact that the link between olanzapine and pulmonary embolus was not previously widely described and therefore it did not immediately figure in the differential diagnosis. The patient made a full recovery.There is an increasing body of circumstantial evidence linking olanzapine to pulmonary embolus. Clinicians should bear this possible association in mind when prescribing the drug and when faced with clinical situations where venous thromboembolism (VTE) is a possible diagnosis. VTE has occasionally been described in therapeutic dose olanzapine therapy, but never in the context of an acute overdose. Khat, a recreational drug, has been linked to arterial, but not venous thrombosis.It is hoped that this case report will further encourage research into these associations, which remain to be proven and quantified.In the context of changing population demographics and increasing global migration, a greater awareness of the potential effects of endemic practices and their potential consequences is essential to the modern-day doctor working in a multi-cultural society.
- Published
- 2010
- Full Text
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