Search

Your search keyword '"Maeurer, Markus"' showing total 1,088 results
Start Over Author "Maeurer, Markus"
1,088 results on '"Maeurer, Markus"'

4. Prolonged SARS-CoV-2 RNA virus shedding and lymphopenia are hallmarks of COVID-19 in cancer patients with poor prognosis

Author

Goubet, Anne-Gaëlle, Dubuisson, Agathe, Geraud, Arthur, Danlos, François-Xavier, Terrisse, Safae, Silva, Carolina Alves Costa, Drubay, Damien, Touri, Lea, Picard, Marion, Mazzenga, Marine, Silvin, Aymeric, Dunsmore, Garett, Haddad, Yacine, Pizzato, Eugenie, Ly, Pierre, Flament, Caroline, Melenotte, Cléa, Solary, Eric, Fontenay, Michaela, Garcia, Gabriel, Balleyguier, Corinne, Lassau, Nathalie, Maeurer, Markus, Grajeda-Iglesias, Claudia, Nirmalathasan, Nitharsshini, Aprahamian, Fanny, Durand, Sylvère, Kepp, Oliver, Ferrere, Gladys, Thelemaque, Cassandra, Lahmar, Imran, Fahrner, Jean-Eudes, Meziani, Lydia, Ahmed-Belkacem, Abdelhakim, Saïdani, Nadia, La Scola, Bernard, Raoult, Didier, Gentile, Stéphanie, Cortaredona, Sébastien, Ippolito, Giuseppe, Lelouvier, Benjamin, Roulet, Alain, Andre, Fabrice, Barlesi, Fabrice, Soria, Jean-Charles, Pradon, Caroline, Gallois, Emmanuelle, Pommeret, Fanny, Colomba, Emeline, Ginhoux, Florent, Kazandjian, Suzanne, Elkrief, Arielle, Routy, Bertrand, Miyara, Makoto, Gorochov, Guy, Deutsch, Eric, Albiges, Laurence, Stoclin, Annabelle, Gachot, Bertrand, Florin, Anne, Merad, Mansouria, Scotte, Florian, Assaad, Souad, Kroemer, Guido, Blay, Jean-Yves, Marabelle, Aurélien, Griscelli, Frank, Zitvogel, Laurence, and Derosa, Lisa

Published
2021
Full Text
View/download PDF

10. “The Impact of Mycobacterium tuberculosis Immune Evasion on Protective Immunity: Implications for TB Vaccine Design” – Meeting report

Author

Boggiano, Cesar, Eichelberg, Katrin, Ramachandra, Lakshmi, Shea, Jaqueline, Ramakrishnan, Lalita, Behar, Samuel, Ernst, Joel D, Porcelli, Steven A, Maeurer, Markus, and Kornfeld, Hardy

Subjects
Medical Microbiology, Biomedical and Clinical Sciences, Immunology, Biodefense, Rare Diseases, Tuberculosis Vaccine, Orphan Drug, Immunization, Infectious Diseases, Prevention, Emerging Infectious Diseases, Tuberculosis, Biotechnology, Lung, HIV/AIDS, Vaccine Related, Aetiology, 2.2 Factors relating to the physical environment, Prevention of disease and conditions, and promotion of well-being, 3.4 Vaccines, Infection, Good Health and Well Being, Drug Discovery, Humans, Immune Evasion, Mycobacterium tuberculosis, Tuberculosis Vaccines, Vaccine, Immune evasion, Biological Sciences, Agricultural and Veterinary Sciences, Medical and Health Sciences, Virology, Biomedical and clinical sciences, Health sciences
Abstract

Tuberculosis (TB) is the major cause of death from infectious diseases around the world, particularly in HIV infected individuals. TB vaccine design and development have been focused on improving Bacille Calmette-Guérin (BCG) and evaluating recombinant and viral vector expressed Mycobacterium tuberculosis (Mtb) proteins, for boosting BCG-primed immunity, but these approaches have not yet yielded significant improvements over the modest effects of BCG in protecting against infection or disease. On March 7-8, 2016, the National Institute of Allergy and Infectious Diseases (NIAID) convened a workshop on "The Impact of Mtb Immune Evasion on Protective Immunity: Implications for TB Vaccine Design" with the goal of defining immune mechanisms that could be targeted through novel research approaches, to inform vaccine design and immune therapeutic interventions for prevention of TB. The workshop addressed early infection events, the impact of Mtb evolution on the development and maintenance of an adaptive immune response, and the factors that influence protection against and progression to active disease. Scientific gaps and areas of study to revitalize and accelerate TB vaccine design were discussed and prioritized. These included a comprehensive evaluation of innate and Mtb-specific adaptive immune responses in the lung at different stages of disease; determining the role of B cells and antibodies (Abs) during Mtb infection; development of better assays to measure Mtb burden following exposure, infection, during latency and after treatment, and approaches to improving current animal models to study Mtb immunogenicity, TB disease and transmission.

Published
2017

12. Expansion of myeloid-derived suppressor cells in patients with severe coronavirus disease (COVID-19)

Author

Agrati, Chiara, Sacchi, Alessandra, Bordoni, Veronica, Cimini, Eleonora, Notari, Stefania, Grassi, Germana, Casetti, Rita, Tartaglia, Eleonora, Lalle, Eleonora, D’Abramo, Alessandra, Castilletti, Concetta, Marchioni, Luisa, Shi, Yufang, Mariano, Andrea, Song, Jin-Wen, Zhang, Ji-Yuan, Wang, Fu-Sheng, Zhang, Chao, Fimia, Gian Maria, Capobianchi, Maria R., Piacentini, Mauro, Antinori, Andrea, Nicastri, Emanuele, Maeurer, Markus, Zumla, Alimuddin, and Ippolito, Giuseppe

Published
2020
Full Text
View/download PDF

13. Effect of human umbilical cord-derived mesenchymal stem cells on lung damage in severe COVID-19 patients: a randomized, double-blind, placebo-controlled phase 2 trial

Author

Shi, Lei, Huang, Hai, Lu, Xuechun, Yan, Xiaoyan, Jiang, Xiaojing, Xu, Ruonan, Wang, Siyu, Zhang, Chao, Yuan, Xin, Xu, Zhe, Huang, Lei, Fu, Jun-Liang, Li, Yuanyuan, Zhang, Yu, Yao, Wei-Qi, Liu, Tianyi, Song, Jinwen, Sun, Liangliang, Yang, Fan, Zhang, Xin, Zhang, Bo, Shi, Ming, Meng, Fanping, Song, Yanning, Yu, Yongpei, Wen, Jiqiu, Li, Qi, Mao, Qing, Maeurer, Markus, Zumla, Alimuddin, Yao, Chen, Xie, Wei-Fen, and Wang, Fu-Sheng

Published
2021
Full Text
View/download PDF

16. Mutant Epitopes in Cancer

Author

Rao, Martin, Zhenjiang, Liu, Meng, Qingda, Sinclair, Georges, Dodoo, Ernest, Maeurer, Markus, Zitvogel, Laurence, editor, and Kroemer, Guido, editor

Published
2018
Full Text
View/download PDF

24. Targeting innate immunity for tuberculosis vaccination

Author

Khader, Shabaana A., Divangahi, Maziar, Hanekom, Willem, Hill, Philip C., Maeurer, Markus, Makar, Karen W., Mayer-Barber, Katrin D., Mhlanga, Musa M., Nemes, Elisa, Schlesinger, Larry S., van Crevel, Reinout, Vankalayapati, Ramakrishna, Xavier, Ramnik J., Netea, Mihai G., and on behalf of the Bill and Melinda Gates Foundation Collaboration for TB Vaccine Discovery Innate Immunity Working Group

Subjects
Antigens -- Health aspects, Tuberculosis vaccines -- Health aspects, Epigenetic inheritance -- Health aspects, Lymphocytes -- Health aspects, BCG -- Health aspects, Antitubercular agents -- Health aspects, Medical research -- Health aspects, Vaccination -- Health aspects, Epidemiology -- Health aspects, Immune response -- Health aspects, Tuberculosis -- Development and progression -- Health aspects, Killer cells, T cells, B cells, Future predictions, Health care industry
Abstract

Vaccine development against tuberculosis (TB) is based on the induction of adaptive immune responses endowed with long-term memory against mycobacterial antigens. Memory B and T cells initiate a rapid and robust immune response upon encounter with Mycobacterium tuberculosis, thus achieving long-lasting protection against infection. Recent studies have shown, however, that innate immune cell populations such as myeloid cells and NK cells also undergo functional adaptation after infection or vaccination, a de facto innate immune memory that is also termed trained immunity. Experimental and epidemiological data have shown that induction of trained immunity contributes to the beneficial heterologous effects of vaccines such as bacille Calmette-Guerin (BCG), the licensed TB vaccine. Moreover, increasing evidence argues that trained immunity also contributes to the anti-TB effects of BCG vaccination. An interaction among immunological signals, metabolic rewiring, and epigenetic reprogramming underlies the molecular mechanisms mediating trained immunity in myeloid cells and their bone marrow progenitors. Future studies are warranted to explore the untapped potential of trained immunity to develop a future generation of TB vaccines that would combine innate and adaptive immune memory induction., Introduction Vaccination has made an enormous contribution to improving human and animal health over the last two centuries (1-6). Despite progress in developing vaccines against a large number of infections, [...]

Published
2019
Full Text
View/download PDF

27. Safety and immunogenicity of the novel H4:IC31 tuberculosis vaccine candidate in BCG-vaccinated adults: Two phase I dose escalation trials

Author

Norrby, Maria, Vesikari, Timo, Lindqvist, Lars, Maeurer, Markus, Ahmed, Raija, Mahdavifar, Shahnaz, Bennett, Sean, McClain, J. Bruce, Shepherd, Barbara M., Li, Daner, Hokey, David A., Kromann, Ingrid, Hoff, Søren T., Andersen, Peter, de Visser, Adriëtte W., Joosten, Simone A., Ottenhoff, Tom H.M., Andersson, Jan, and Brighenti, Susanna

Published
2017
Full Text
View/download PDF

36. Learning from epidemiological, clinical, and immunological studies on Mycobacterium africanum for improving current understanding of host–pathogen interactions, and for the development and evaluation of diagnostics, host-directed therapies, and vaccines for tuberculosis

Author

Zumla, Alimuddin, Otchere, Isaac Darko, Mensah, Gloria Ivy, Asante-Poku, Adwoa, Gehre, Florian, Maeurer, Markus, Bates, Matthew, Mwaba, Peter, Ntoumi, Francine, and Yeboah-Manu, Dorothy

Published
2017
Full Text
View/download PDF

37. Early expansion of myeloid-derived suppressor cells inhibits SARS-CoV-2 specific T-cell response and may predict fatal COVID-19 outcome

Author

Sacchi, Alessandra, Grassi, Germana, Bordoni, Veronica, Lorenzini, Patrizia, Cimini, Eleonora, Casetti, Rita, Tartaglia, Eleonora, Marchioni, Luisa, Petrosillo, Nicola, Palmieri, Fabrizio, D’Offizi, Gianpiero, Notari, Stefania, Tempestilli, Massimo, Capobianchi, Maria Rosaria, Nicastri, Emanuele, Maeurer, Markus, Zumla, Alimuddin, Locatelli, Franco, Antinori, Andrea, Ippolito, Giuseppe, and Agrati, Chiara

Published
2020
Full Text
View/download PDF

41. Data from The Polarity and Specificity of Antiviral T Lymphocyte Responses Determine Susceptibility to SARS-CoV-2 Infection in Patients with Cancer and Healthy Individuals

Author

Fahrner, Jean-Eudes, primary, Lahmar, Imran, primary, Goubet, Anne-Gaëlle, primary, Haddad, Yacine, primary, Carrier, Agathe, primary, Mazzenga, Marine, primary, Drubay, Damien, primary, Alves Costa Silva, Carolina, primary, de Sousa, Eric, primary, Thelemaque, Cassandra, primary, Melenotte, Cléa, primary, Dubuisson, Agathe, primary, Geraud, Arthur, primary, Ferrere, Gladys, primary, Birebent, Roxanne, primary, Bigenwald, Camille, primary, Picard, Marion, primary, Cerbone, Luigi, primary, Lérias, Joana R., primary, Laparra, Ariane, primary, Bernard-Tessier, Alice, primary, Kloeckner, Benoît, primary, Gazzano, Marianne, primary, Danlos, François-Xavier, primary, Terrisse, Safae, primary, Pizzato, Eugenie, primary, Flament, Caroline, primary, Ly, Pierre, primary, Tartour, Eric, primary, Benhamouda, Nadine, primary, Meziani, Lydia, primary, Ahmed-Belkacem, Abdelhakim, primary, Miyara, Makoto, primary, Gorochov, Guy, primary, Barlesi, Fabrice, primary, Trubert, Alexandre, primary, Ungar, Benjamin, primary, Estrada, Yeriel, primary, Pradon, Caroline, primary, Gallois, Emmanuelle, primary, Pommeret, Fanny, primary, Colomba, Emeline, primary, Lavaud, Pernelle, primary, Deloger, Marc, primary, Droin, Nathalie, primary, Deutsch, Eric, primary, Gachot, Bertrand, primary, Spano, Jean-Philippe, primary, Merad, Mansouria, primary, Scotté, Florian, primary, Marabelle, Aurélien, primary, Griscelli, Frank, primary, Blay, Jean-Yves, primary, Soria, Jean-Charles, primary, Merad, Miriam, primary, André, Fabrice, primary, Villemonteix, Juliette, primary, Chevalier, Mathieu F., primary, Caillat-Zucman, Sophie, primary, Fenollar, Florence, primary, Guttman-Yassky, Emma, primary, Launay, Odile, primary, Kroemer, Guido, primary, La Scola, Bernard, primary, Maeurer, Markus, primary, Derosa, Lisa, primary, and Zitvogel, Laurence, primary

Published
2023
Full Text
View/download PDF

42. Supplementary Data from The Polarity and Specificity of Antiviral T Lymphocyte Responses Determine Susceptibility to SARS-CoV-2 Infection in Patients with Cancer and Healthy Individuals

Author

Fahrner, Jean-Eudes, primary, Lahmar, Imran, primary, Goubet, Anne-Gaëlle, primary, Haddad, Yacine, primary, Carrier, Agathe, primary, Mazzenga, Marine, primary, Drubay, Damien, primary, Alves Costa Silva, Carolina, primary, de Sousa, Eric, primary, Thelemaque, Cassandra, primary, Melenotte, Cléa, primary, Dubuisson, Agathe, primary, Geraud, Arthur, primary, Ferrere, Gladys, primary, Birebent, Roxanne, primary, Bigenwald, Camille, primary, Picard, Marion, primary, Cerbone, Luigi, primary, Lérias, Joana R., primary, Laparra, Ariane, primary, Bernard-Tessier, Alice, primary, Kloeckner, Benoît, primary, Gazzano, Marianne, primary, Danlos, François-Xavier, primary, Terrisse, Safae, primary, Pizzato, Eugenie, primary, Flament, Caroline, primary, Ly, Pierre, primary, Tartour, Eric, primary, Benhamouda, Nadine, primary, Meziani, Lydia, primary, Ahmed-Belkacem, Abdelhakim, primary, Miyara, Makoto, primary, Gorochov, Guy, primary, Barlesi, Fabrice, primary, Trubert, Alexandre, primary, Ungar, Benjamin, primary, Estrada, Yeriel, primary, Pradon, Caroline, primary, Gallois, Emmanuelle, primary, Pommeret, Fanny, primary, Colomba, Emeline, primary, Lavaud, Pernelle, primary, Deloger, Marc, primary, Droin, Nathalie, primary, Deutsch, Eric, primary, Gachot, Bertrand, primary, Spano, Jean-Philippe, primary, Merad, Mansouria, primary, Scotté, Florian, primary, Marabelle, Aurélien, primary, Griscelli, Frank, primary, Blay, Jean-Yves, primary, Soria, Jean-Charles, primary, Merad, Miriam, primary, André, Fabrice, primary, Villemonteix, Juliette, primary, Chevalier, Mathieu F., primary, Caillat-Zucman, Sophie, primary, Fenollar, Florence, primary, Guttman-Yassky, Emma, primary, Launay, Odile, primary, Kroemer, Guido, primary, La Scola, Bernard, primary, Maeurer, Markus, primary, Derosa, Lisa, primary, and Zitvogel, Laurence, primary

Published
2023
Full Text
View/download PDF

43. Supplementary Figure from The Polarity and Specificity of Antiviral T Lymphocyte Responses Determine Susceptibility to SARS-CoV-2 Infection in Patients with Cancer and Healthy Individuals

Author

Fahrner, Jean-Eudes, primary, Lahmar, Imran, primary, Goubet, Anne-Gaëlle, primary, Haddad, Yacine, primary, Carrier, Agathe, primary, Mazzenga, Marine, primary, Drubay, Damien, primary, Alves Costa Silva, Carolina, primary, de Sousa, Eric, primary, Thelemaque, Cassandra, primary, Melenotte, Cléa, primary, Dubuisson, Agathe, primary, Geraud, Arthur, primary, Ferrere, Gladys, primary, Birebent, Roxanne, primary, Bigenwald, Camille, primary, Picard, Marion, primary, Cerbone, Luigi, primary, Lérias, Joana R., primary, Laparra, Ariane, primary, Bernard-Tessier, Alice, primary, Kloeckner, Benoît, primary, Gazzano, Marianne, primary, Danlos, François-Xavier, primary, Terrisse, Safae, primary, Pizzato, Eugenie, primary, Flament, Caroline, primary, Ly, Pierre, primary, Tartour, Eric, primary, Benhamouda, Nadine, primary, Meziani, Lydia, primary, Ahmed-Belkacem, Abdelhakim, primary, Miyara, Makoto, primary, Gorochov, Guy, primary, Barlesi, Fabrice, primary, Trubert, Alexandre, primary, Ungar, Benjamin, primary, Estrada, Yeriel, primary, Pradon, Caroline, primary, Gallois, Emmanuelle, primary, Pommeret, Fanny, primary, Colomba, Emeline, primary, Lavaud, Pernelle, primary, Deloger, Marc, primary, Droin, Nathalie, primary, Deutsch, Eric, primary, Gachot, Bertrand, primary, Spano, Jean-Philippe, primary, Merad, Mansouria, primary, Scotté, Florian, primary, Marabelle, Aurélien, primary, Griscelli, Frank, primary, Blay, Jean-Yves, primary, Soria, Jean-Charles, primary, Merad, Miriam, primary, André, Fabrice, primary, Villemonteix, Juliette, primary, Chevalier, Mathieu F., primary, Caillat-Zucman, Sophie, primary, Fenollar, Florence, primary, Guttman-Yassky, Emma, primary, Launay, Odile, primary, Kroemer, Guido, primary, La Scola, Bernard, primary, Maeurer, Markus, primary, Derosa, Lisa, primary, and Zitvogel, Laurence, primary

Published
2023
Full Text
View/download PDF

44. Supplementary Figure 1 from Phase I Clinical Trial of Mixed Bacterial Vaccine (Coley's Toxins) in Patients with NY-ESO-1 Expressing Cancers: Immunological Effects and Clinical Activity

Author

Karbach, Julia, primary, Neumann, Antje, primary, Brand, Kathrin, primary, Wahle, Claudia, primary, Siegel, Ekkehard, primary, Maeurer, Markus, primary, Ritter, Erika, primary, Tsuji, Takamasa, primary, Gnjatic, Sacha, primary, Old, Lloyd J., primary, Ritter, Gerd, primary, and Jäger, Elke, primary

Published
2023
Full Text
View/download PDF

45. Supplementary Figure 4 from Phase I Clinical Trial of Mixed Bacterial Vaccine (Coley's Toxins) in Patients with NY-ESO-1 Expressing Cancers: Immunological Effects and Clinical Activity

Author

Karbach, Julia, primary, Neumann, Antje, primary, Brand, Kathrin, primary, Wahle, Claudia, primary, Siegel, Ekkehard, primary, Maeurer, Markus, primary, Ritter, Erika, primary, Tsuji, Takamasa, primary, Gnjatic, Sacha, primary, Old, Lloyd J., primary, Ritter, Gerd, primary, and Jäger, Elke, primary

Published
2023
Full Text
View/download PDF

46. Supplementary Methods and Figure Legend from Phase I Clinical Trial of Mixed Bacterial Vaccine (Coley's Toxins) in Patients with NY-ESO-1 Expressing Cancers: Immunological Effects and Clinical Activity

Author

Karbach, Julia, primary, Neumann, Antje, primary, Brand, Kathrin, primary, Wahle, Claudia, primary, Siegel, Ekkehard, primary, Maeurer, Markus, primary, Ritter, Erika, primary, Tsuji, Takamasa, primary, Gnjatic, Sacha, primary, Old, Lloyd J., primary, Ritter, Gerd, primary, and Jäger, Elke, primary

Published
2023
Full Text
View/download PDF

47. Supplementary Figure 3 from Phase I Clinical Trial of Mixed Bacterial Vaccine (Coley's Toxins) in Patients with NY-ESO-1 Expressing Cancers: Immunological Effects and Clinical Activity

Author

Karbach, Julia, primary, Neumann, Antje, primary, Brand, Kathrin, primary, Wahle, Claudia, primary, Siegel, Ekkehard, primary, Maeurer, Markus, primary, Ritter, Erika, primary, Tsuji, Takamasa, primary, Gnjatic, Sacha, primary, Old, Lloyd J., primary, Ritter, Gerd, primary, and Jäger, Elke, primary

Published
2023
Full Text
View/download PDF

48. Supplementary Figure 2 from Phase I Clinical Trial of Mixed Bacterial Vaccine (Coley's Toxins) in Patients with NY-ESO-1 Expressing Cancers: Immunological Effects and Clinical Activity

Author

Karbach, Julia, primary, Neumann, Antje, primary, Brand, Kathrin, primary, Wahle, Claudia, primary, Siegel, Ekkehard, primary, Maeurer, Markus, primary, Ritter, Erika, primary, Tsuji, Takamasa, primary, Gnjatic, Sacha, primary, Old, Lloyd J., primary, Ritter, Gerd, primary, and Jäger, Elke, primary

Published
2023
Full Text
View/download PDF

49. World tuberculosis day 2023 – Reflections on the spread of drug-resistant tuberculosis by travellers and reducing risk in forcibly displaced populations

Author

Rodriguez-Morales, Alfonso J., primary, Abbara, Aula, additional, Ntoumi, Francine, additional, Kapata, Nathan, additional, Mwaba, Peter, additional, Yeboah-Manu, Dorothy, additional, Maeurer, Markus, additional, Dar, Osman, additional, Abubakar, Ibrahim, additional, and Zumla, Alimuddin, additional

Published
2023
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results