99 results on '"Maglitto, F."'
Search Results
2. Management of Oroantral Communications using Platelet-Rich Fibrin: our experience
- Author
-
Dell'Aversana Orabona G., Maglitto F., Committeri U., Romano A., Sani L., Troise S., Arena A., Audino G., Norino G., Del Prete G. D., Navarro Cuellar C., Iaconetta G., Califano L., Dell'Aversana Orabona, G., Maglitto, F., Committeri, U., Romano, A., Sani, L., Troise, S., Arena, A., Audino, G., Norino, G., Del Prete, G. D., Navarro Cuellar, C., Iaconetta, G., and Califano, L.
- Subjects
Oral surgery ,Fistula ,Maxillofacial surgery ,Oroantral communication ,Platelet-Rich Fibrin (PRF) ,Sinus surgery - Abstract
Aims Oroantral communication (OAC) represents an opening between the maxillary sinus and the oral cavity most commonly caused by the extraction of maxillary posterior teeth (80%). The aim of the present study was to evaluate the efficacy and reliability of treating OACs using plasma-rich fibrin (PRF). Also, the most significant recent papers on the topic are briefly summarized in order to compare the surgical procedure and results Materials and methods A retrospective study was conducted in the Maxillofacial Surgery Unit of the Federico II University of Naples from April 2017 to December 2020. A total of 102 OAC patients with a lesion of a diameter of 5 mm or more were enrolled in the study and surgically treated, 63 patients were treated with PRF alone; 39 patients were treated with a buccal flap or buccal fat pad. Results Locoregional healing of the surgical area was observed between 3 and 4 weeks in all patients, no recurrences were recorded. At 6 months the mucous membrane of the maxillary sinus is completely regenerated and resumes normal mucociliary functions. Conclusion Surgical treatment of OAC with PRF is a less invasive surgical technique than using mucous flaps or buccal fat pad. PRF is an autologous material that contains growth factors and allows to preserve the height of the vestibular sulcus. The results of our study showed that PRF can be easily performed and guarantees excellent results in the treatment of OACs with a diameter equal to or greater than 5 mm with a low risk of complications.
- Published
- 2022
3. Electrochemotherapy as palliative treatment in patients with recurrent and/or metastatic head and neck tumours: features analysis for an early determination of the partial responsive patients
- Author
-
Maglitto, F., Salzano, G., Longo, F., DI BERNARDO, E., D’Alessio, V., Fusco, R., Aversa, C., Pavone, E., Pontone, M., Marciano, M. L., Togo, G., DE FAZIO, G. R., Ordano, D., Maglione, M. G., Vaira, L. A., Bergonzani, M., Salzano, F. A., Maiolino, P., Califano1, L., Ionna, F., and Perri, F.
- Subjects
Bleomycin ,Skin Neoplasms ,Treatment Outcome ,Head and Neck Neoplasms ,Electrochemotherapy ,Palliative Care ,Quality of Life ,Humans ,Pain - Abstract
The aim of this study was to identify features mainly involved in determining the partial response (PR) to the Electrochemotherapy (ECT) in patients with recurrent and/or metastatic head and neck (HN) tumor; the identified features were also used in a decision chart in order to provide the clinician with a support tool in deciding further therapies.131 patients (186 treatment sessions) with recurrent and/or metastatic HN neoplasm were subjected to ECT. Treatment response was evaluated based on Response Evaluation Criteria in Solid Tumors (RECIST) v. 1.1 two months after the ECT. The grade of bleeding and pain before, at the end and one week after ECT treatment were evaluated. Univariate and multivariate analysis were performed to identify features involved in determining the patient PR.In the context of the univariate analysis, tumor size significantly influenced the response to ECT, with higher PR rate of 58.3%: 28 among 48 patients with lesion size ≤ 3 centimeters (p-value0.001 at Chi-square test). Pain and bleeding pre-treatment were positively correlated to PR (p-value0.001 at Chi-square test). A difference in the current flowing in the tissue during treatment was also observed in partially responsive patients, where the median current value (6.6 A) was higher than that achieved in patients that did not show PR (3.3 A). In the context of the multivariate analysis, the best performances are achieved with the BART method (accuracy of 84%). The main clinical factors to predict the partial response, among investigated features, that have shown to be considered were the pain value felt before performing the treatment and the median current delivered during the ECT treatment. A decision-making support tool to predict the patient prognosis in terms of response rate could be represented by the decision tree obtained with CART algorithm, where a pain pre-treatment more than 5 and a median delivered current not less than 2.8 A led to the prediction a partial responsive patient with an accuracy of 75%.The study confirmed that ECT is an interesting antitumoral therapy in advanced chemo- and radio-refractory HN neoplasms, able to reduce frequent symptoms and to improve the quality of life. Pain pre-treatment and delivered current are the most important variables when predicting the partial response of patients.
- Published
- 2022
4. Six-month smell and taste recovery rates in coronavirus disease 2019 patients: A prospective psychophysical study
- Author
-
Petrocelli, M., Cutrupi, S., Salzano, G., Maglitto, F., Salzano, F. A., Lechien, J. R., Saussez, S., Boscolo-Rizzo, P., Riu, De, Vaira, G., and L. A.
- Subjects
COVID-19 ,Olfactor disorder ,Taste ,Smell ,Anosmia ,Ageusia ,Sars-Cov-2 ,Coronavirus - Published
- 2021
5. Six-month smell and taste recovery rates in coronavirus disease 2019 patients: a prospective psychophysical study
- Author
-
Petrocelli, M, primary, Cutrupi, S, additional, Salzano, G, additional, Maglitto, F, additional, Salzano, F A, additional, Lechien, J R, additional, Saussez, S, additional, Boscolo-Rizzo, P, additional, De Riu, G, additional, and Vaira, L A, additional
- Published
- 2021
- Full Text
- View/download PDF
6. The impact of COVID-19 pandemic on surgical residency programmes in Italy: a nationwide analysis on behalf of the Italian Polyspecialistic Young Surgeons Society (SPIGC)
- Author
-
Pertile, D., Gallo, G., Barra, F., Pasculli, A., Batistotti, P., Sparavigna, M., Vizzielli, G., Soriero, D., Graziano, G., Di Saverio, S., Meniconi, R. L., Guaitoli, E., Mazzarri, A., Aprile, A., Aprile, V., Botteri, E., Brascia, D., Cozza, V., Damarco, F., Di Marco, C., Gallazzi, M., Giovenzana, M., Giuffrida, M., Lanari, J., Lanza, G., Lo Surdo, P., Maglitto, F., Manitto, M., Minuzzo, A., Montelione, N., Palmieri, G., Pasqui, E., Perelli, F., Piovano, E., Portigliotti, L., Ribolla, M., Romano, A., Romboli, A., Sena, G., Settembrini, A., Sturiale, A., Velluti, F., 1, Davide Pertile, 2, Gaetano Gallo, 3, Fabio Barra, 4, Alessandro Pasculli, 1, Paola Batistotti, 1, Marco Sparavigna, 5, Giuseppe Vizzielli, 1, Domenico Soriero, 6, Giusi Graziano, 7, Salomone Di Saverio, 8, Roberto Luca Meniconi, 9, Eleonora Guaitoli, Mazzarri 10, Andrea, Working Group (Alessandra Aprile, Spigc, Aprile, Vittorio, Botteri, Emanuele, Brascia, Debora, Cozza, Valerio, Damarco, Francesco, Di Marco, Carlo, Gallazzi, Mariasole, Giovenzana, Marco, Giuffrida, Mario, Lanari, Jacopo, Lanza, Giovanni, Lo Surdo, Pasquale, Maglitto, Fabio, Manitto, Mattia, Minuzzo, Alessio, Montelione, Nunzio, Palmieri, Gerardo, Pasqui, Edoardo, Perelli, Federica, Piovano, Elisa, Portigliotti, Luca, Ribolla, Marta, Romano, Angela, Romboli, Andrea, Sena, Giuseppe, Settembrini, Alberto, Sturiale, Alessandro, and Velluti), Francesco
- Subjects
medicine.medical_specialty ,Coronavirus disease 2019 (COVID-19) ,Demographics ,Pneumonia, Viral ,Surgical activity ,Economic shortage ,Subgroup analysis ,030230 surgery ,Italian surgical residents ,Specialties, Surgical ,03 medical and health sciences ,0302 clinical medicine ,Clinical activity ,Medical ,Surgical ,Surveys and Questionnaires ,Pandemic ,medicine ,Humans ,Viral ,COVID-19 ,Research activity ,Survey ,Internship and Residency ,Italy ,Societies, Medical ,Coronavirus Infections ,Pandemics ,Training programme ,Government ,business.industry ,Pneumonia ,Surgery ,030220 oncology & carcinogenesis ,Family medicine ,Original Article ,business ,Societies ,Specialties ,Regional differences - Abstract
Introduction Recently, Italy has been heavily hit by COVID-19 pandemic and today it is still one of the most affected countries in the world. The subsequent necessary lockdown decreed by the Italian Government had an outstanding impact on the daily life of the entire population, including that of Italian surgical residents’ activity. Our survey aims to evaluate the impact of COVID-19 on the training programme of Italian surgical residents. Materials and methods We designed a 12-item-electronic anonymous questionnaire on SurveyMonkey© web application. The survey was composed of different sections concerning demographic characteristics and impacts of COVID-19 on the concrete participation in clinical, surgical and research activities. Future perspectives of responders after the pandemic were also investigated. Results Eighty hundred responses were collected, and 756 questionnaires were considered eligible to be included in the study analysis. Almost 35 and 27% of respondents experienced, respectively, complete interruption of surgical and clinical activities. A subgroup analysis, comparing the COVID-19 impact on clinical activities with demographics data, showed a statistically significant difference related to specialties (p = 0.0062) and Italian regions (p
- Published
- 2020
7. Infective complications after free flaps reconstruction in patients affected by head and neck cancer Our experience on 77 cases
- Author
-
Orabona, G. D. A., Corvino, R., Maglitto, F., Abbate, V., Paola Bonavolontà, Romano, A., Salzano, G., Califano, L., Orabona, Giovanni Dell'Aversana, Corvino, Raffaele, Maglitto, Fabio, Abbate, Vincenzo, Bonavolontà, Paola, Romano, Antonio, Salzano, Giovanni, and Califano, Luigi
- Subjects
Free flaps ,Infective complications ,Head and neck cancer - Abstract
The success rates of free flaps in patients undergoing head and neck cancer (HNC) surgery are very high (95%- 97%) but the development of a surgical site infection (SSI) can put flap viability at risk. The aim of our study is to identify the risk factors for SSI in patients undergo free flaps reconstruction after head and neck cancer removal.
- Published
- 2018
8. Castleman's disease mimicking a parotid gland tumor: report of a case and review of the literature
- Author
-
Iaconetta G, Friscia M, Dell'Aversana Orabona G, de Biasi S, Romano A, Piombino P, Graziano P, Abbate V, Giovanni Salzano, Maglitto F, Califano L, Iaconetta, G, Friscia, M, DELL'AVERSANA ORABONA, Giovanni, de Biasi, S, Romano, A, Piombino, P, Graziano, P, Abbate, Vincenzo, Salzano, G, Maglitto, F, Califano, Luigi, G., Iaconetta, M., Friscia, G., Dell’Aversana Orabona, S., de Biasi, A., Romano, Piombino, Pasquale, P., Graziano, V., Abbate, G., Salzano, F., Maglitto, and L., Califano
- Subjects
Adult ,Diagnosis, Differential ,Castleman’s disease, Angiofollicular hyperplasia, Benign giant lymphoma, Head and neck ,Treatment Outcome ,Predictive Value of Tests ,Biopsy ,Castleman Disease ,Humans ,Castleman's disease ,Female ,Tomography, X-Ray Computed ,Parotid Neoplasms - Abstract
Castleman's disease (giant lymph node hyperplasia, angiofollicular hyperplasia, lymphoid hamartoma, benign giant lymphoma), is a quite rare and complex disease of lymphoid tissue that causes progressive lymph node enlargement, typically presenting as a solitary mediastinal mass. It was first described by Castleman et al in 1956. The head and neck regions are the second, less common site for this lesion. The preoperative diagnosis is very often extremely difficult and the routine investigations are often inconclusive. A multicentric extension of this disease shows poorer prognosis compared to the unifocal Histologically, three types do exist: the hyaline-vascular type, the plasma cell type and the mixed type. The etiology and pathogenesis is still unclear. In the literature, to our knowledge, only 112 cases have been reported involving head and neck, and only 22, including our own, interesting the parotid gland. In this report we describe a rare singular of Castleman's disease presenting as a tumor of the inferior pole of the parotid gland extending in the submandibular region, in a 35-year-old woman. The patient undergone a surgical treatment and, therefore, the mass was successfully totally removed.
- Published
- 2014
9. Bilateral hypertrophy of masseteric and temporalis muscles, our fifteen patients and review of literature.
- Author
-
GRAZIANO, P., DELL'AVERSANA ORABONA, G., ASTARITA, F., PONZO, L. M., NUNZIATA, R., SALZANO, G., MAGLITTO, F., SOLARI, D., SANTELLA, A., CAPPABIANCA, M., IACONETTA, G., and CALIFANO, L.
- Abstract
OBJECTIVE: The association of bilateral hypertrophy of temporalis and masseteric muscles is a rare clinical entity. The origin of the condition is unclear, causing cosmetic problems, pain, and functional impairment. PATIENTS AND METHODS: In this paper we analyzed 15 patients treated at the Department of Maxillo-Facial Surgery of the University of Naples Federico II, from 2000 to 2013, for temporalis and/or masseteric muscle hypertrophy, and in particular, a rare case of a patient with a marked bilateral swelling of the temporalis and masseteric region, in conjunction with a review of the literature. RESULTS: Fourteen patients have not any kind of postoperatively problems. The last patient had been aware of the swelling for many years and complained of recurrent headaches. We adopted a new protocol fort these patients and the patient was very pleased with the treatment results, and reported a reduction in headaches and a continuation of his well-being, in addition to greater self-confidence. The last follow-up was performed three years after the first treatment, and the patient showed a complete resolution of his symptoms, and just a small increase of the swelling. CONCLUSIONS: The treatment of temporalis and masseteric hypertrophy with Botulin toxin could be an effective option compared to conservative treatment or surgical intervention although the review of the literature shows that this is only a temporary treatment. In fact, surgery still remains the best option. The treatment must be repeated every 4/6 months for 2-3 consecutive years before having stable benefits. To overcome this problem, an association with a bite treatment allowed us to achieve more lasting and more stable results over time without a recurrence of symptoms between the treatments. Furthermore, this association has enabled us to obtain a more rapid reduction of the hypertrophy. [ABSTRACT FROM AUTHOR]
- Published
- 2016
10. Castleman's disease mimicking a parotid gland tumor: report of a case and review of the literature.
- Author
-
IACONETTA, G., FRISCIA, M., DELL''AVERSANA ORABONA, G., DE BIASI, S., ROMANO, A., PIOMBINO, P., GRAZIANO, P., ABBATE, V., SALZANO, G., MAGLITTO, F., and CALIFANO, L.
- Abstract
Castleman's disease (giant lymph node hyperplasia, angiofollicular hyperplasia, lymphoid hamartoma, benign giant lymphoma), is a quite rare and complex disease of lymphoid tissue that causes progressive lymph node enlargement, typically presenting as a solitary mediastinal mass. It was first described by Castleman et al in 1956. The head and neck regions are the second, less common site for this lesion. The preoperative diagnosis is very often extremely difficult and the routine investigations are often inconclusive. A multicentric extension of this disease shows poorer prognosis compared to the unifocal Histologically, three types do exist: the hyaline-vascular type, the plasma cell type and the mixed type. The etiology and pathogenesis is still unclear. In the literature, to our knowledge, only 112 cases have been reported involving head and neck, and only 22, including our own, interesting the parotid gland. In this report we describe a rare singular of Castleman's disease presenting as a tumor of the inferior pole of the parotid gland extending in the submandibular region, in a 35-year-old woman. The patient undergone a surgical treatment and, therefore, the mass was successfully totally removed. [ABSTRACT FROM AUTHOR]
- Published
- 2014
11. Prevalence of olfactory dysfunction in D614G, alpha, delta and omicron waves: a psychophysical case-control study
- Author
-
L A, Vaira, J R, Lechien, G, Deiana, G, Salzano, F, Maglitto, P, Piombino, A, Mazzatenta, P, Boscolo-Rizzo, C, Hopkins, G, De Riu, Vaira, L A, Lechien, J R, Deiana, G, Salzano, G, Maglitto, F, Piombino, P, Mazzatenta, A, Boscolo-Rizzo, Paolo, Hopkins, C, and De Riu, G
- Subjects
Delta variant ,SARS-CoV-2 ,coronavirus ,COVID-19 ,Maxillofacial surgery ,olfactory function ,General Medicine ,Omicron variant ,D614G ,olfactory dysfunction ,coronaviru ,taste ,Otorhinolaryngology ,Alpha variant ,smell ,taste dysfunction ,anosmia ,ageusia ,variant of concern - Abstract
Background: The purpose of this study was to compare the prevalence of olfactory dysfunction (OD) at different stages of the COVID-19 pandemic by evaluating subjects diagnosed with SARS-CoV-2 infection during the Omicron wave with psychophysical tests and comparing the results with those obtained from patients infected during the D614G, Alpha and Delta waves and with those of a control group. Methodology: The study included adult patients diagnosed with SARS-CoV-2 infection. Depending on the time of diagnosis, the subjects were divided into four study groups: D614G; Alpha, Delta and Omicron variant groups. A group of uninfected individuals was used as control. All subjects underwent psychophysical evaluation of the olfactory function with the Connecticut Chemosensory Clinical Research Center olfactory test (D614G and Alpha groups) or the extended version of the Sniffin'Sticks test (Delta, Omicron and control groups). Results: 372 cases (134 D614G group, 118 Alpha group, 32 in Delta group and 88 Omicron group) were recruited and evaluated within 10 days of infection, alongside 80 controls. Patients self-reported olfactory loss in 72.4% of cases in the D614G group, in 75.4% of cases in the Alpha group, in 65.6% of cases in the Delta group and in 18.1% in the Omicron group. Psychophysical evaluation revealed a prevalence of OD: 80.6%, 83.0%, 65.6% and 36.3% in the D614G, Alpha, Delta and Omicron group respectively. The differences between the D614G, Alpha and Delta groups were not statistically significant. The Omicron group demonstrated a significantly lower prevalence of OD than the other variants but still significantly higher than the controls. Conclusions: During the Omicron wave OD was less prevalent than during the D614G, Alpha and Delta periods. One-third of patients have reduced olfactory function on psychophysical evaluation during the Omicron wave. Our results should be considered with caution as the VOC has not been determined with certainty.
- Published
- 2023
12. Three Different Types of Fat Grafting for Facial Systemic Sclerosis: A Case Series
- Author
-
Antonio Arena, Umberto Committeri, Fabio Maglitto, Giovanni Salzano, Giovanni Dell’Aversana Orabona, Luigi Angelo Vaira, Pasquale Piombino, Michela Apolito, Gianluca Renato De Fazio, Luigi Califano, Arena, A., Committeri, U., Maglitto, F., Salzano, G., Dell'Aversana Orabona, G., Vaira, L. A., Piombino, P., Apolito, M., De Fazio, G. R., and Califano, L.
- Subjects
systemic sclerosis ,General Medicine ,lipofilling ,maxillo-facial surgery ,fat graft ,orofacial SSc - Abstract
Systemic sclerosis (SSc) is a heterogeneous, chronic connective tissue disease, characterized by skin fibrosis as well as vascular and visceral lesions. It can involve the lungs, heart, kidneys, gastrointestinal tract, and bones. The orofacial manifestations of SSc can cause functional, aesthetic, and social distress, resulting in significant psychological implications for the patients. In recent decades, fat grafting improved the aesthetic outcomes in terms of volume deficiency, contour asymmetry, and skin elasticity of the face thanks to the regenerative action of the stem cells contained within it. We describe five cases of a patient with SSc treated with fat grafting used to correct volume loss and facial elasticity of the lips and perioral region on the middle and lower third of the face. All the patients received regular postoperative checks at weeks 1 and 2. A multiple choice questionnaire was administered to assess the degree of tolerability of the procedure. The reliability of the questionnaire was evaluated by calculating the Cronbach alpha using the MedCalc Statistical Software version 20.113. The aim of our study is to describe three different types of fat grafting used to correct volume loss and restore facial elasticity of the lips and perioral region on the middle and lower third of the face.
- Published
- 2022
- Full Text
- View/download PDF
13. Six-month smell and taste recovery rates in coronavirus disease 2019 patients: a prospective psychophysical study
- Author
-
G De Riu, Luigi Angelo Vaira, Jerome R. Lechien, Paolo Boscolo-Rizzo, S Cutrupi, Fabio Maglitto, Francesco Antonio Salzano, Giovanni Salzano, Sven Saussez, Marzia Petrocelli, Petrocelli, M, Cutrupi, S, Salzano, G, Maglitto, F, A Salzano, F, R Lechien, J, Saussez, S, Boscolo-Rizzo, P, De Riu, G, and A Vaira, L
- Subjects
Adult ,Male ,Olfactory system ,Pediatrics ,medicine.medical_specialty ,Taste ,Coronavirus disease 2019 (COVID-19) ,Anosmia ,medicine.disease_cause ,Olfaction Disorders ,Taste Disorders ,Olfaction Disorder ,Psychophysics ,medicine ,Humans ,Prospective Studies ,Prospective cohort study ,Coronavirus ,SARS-CoV-2 ,business.industry ,Incidence ,Incidence (epidemiology) ,Main Articles ,COVID-19 ,Recovery of Function ,General Medicine ,Middle Aged ,Ageusia ,Smell ,Italy ,Otorhinolaryngology ,Female ,medicine.symptom ,business ,Follow-Up Studies - Abstract
BackgroundThe long-term recovery rate for coronavirus disease 2019 related chemosensory disturbances has not yet been clarified.MethodsOlfactory and gustatory functions were assessed with psychophysical tests in patients in the first seven days from coronavirus disease 2019 onset and one, two, three and six months after the first evaluation.ResultsA total of 300 patients completed the study. The improvement in olfactory function was significant at the two-month follow up. At the end of the observation period, 27 per cent of the patients still experienced a persistent olfactory disturbance, including anosmia in 5 per cent of cases. As for taste, the improvement in the psychophysical scores was significant only between the baseline and the 30-day control. At the 6-month evaluation, 10 per cent of the patients presented with a persistent gustatory disturbance with an incidence of complete ageusia of 1 per cent.ConclusionSix months after the onset of coronavirus disease 2019, about 6 per cent of patients still had a severe persistent olfactory or gustatory disturbance.
- Published
- 2021
- Full Text
- View/download PDF
14. Special Issue 'New Frontiers in Facial Surgery'
- Author
-
Giovanni Dell’Aversana Orabona, Fabio Maglitto, Vincenzo Abbate, Antonio Romano, Paola Bonavolontà, Luigi Califano, Orabona, G. D., Maglitto, F., Abbate, V., Romano, A., Bonavolonta, P., and Califano, L.
- Subjects
General Medicine - Abstract
Facial surgery remains a challenge for surgeons in order to achieve the best results, both functionally and aesthetically [...]
- Published
- 2022
15. Radiomics Metrics Combined with Clinical Data in the Surgical Management of Early-Stage (cT1-T2 N0) Tongue Squamous Cell Carcinomas: A Preliminary Study
- Author
-
Umberto Committeri, Roberta Fusco, Elio Di Bernardo, Vincenzo Abbate, Giovanni Salzano, Fabio Maglitto, Giovanni Dell’Aversana Orabona, Pasquale Piombino, Paola Bonavolontà, Antonio Arena, Francesco Perri, Maria Grazia Maglione, Sergio Venanzio Setola, Vincenza Granata, Giorgio Iaconetta, Franco Ionna, Antonella Petrillo, Luigi Califano, Committeri, U., Fusco, R., Di Bernardo, E., Abbate, V., Salzano, G., Maglitto, F., Dell'Aversana Orabona, G., Piombino, P., Bonavolonta, P., Arena, A., Perri, F., Maglione, M. G., Setola, S. V., Granata, V., Iaconetta, G., Ionna, F., Petrillo, A., and Califano, L.
- Subjects
depth of invasion (DOI) ,oral tongue squamous cell carcinoma (OTSCC) ,machine learning ,General Immunology and Microbiology ,radiomics ,inflammatory index ,neck dissection ,General Agricultural and Biological Sciences ,General Biochemistry, Genetics and Molecular Biology - Abstract
Objective: To predict the risk of metastatic lymph nodes and the tumor grading related to oral tongue squamous cell carcinoma (OTSCC) through the combination of clinical data with radiomics metrics by computed tomography, and to develop a supportive approach in the management of the lymphatic cervical areas, with particular attention to the early stages (T1−T2). Between March 2016 and February 2020, patients with histologically confirmed OTSCC, treated by partial glossectomy and ipsilateral laterocervical lymphadenectomy and subjected to computed tomography (CT) before surgery, were identified by two centers: 81 patients (49 female and 32 male) with 58 years as the median age (range 19–86 years). Univariate analysis with non-parametric tests and multivariate analysis with machine learning approaches were used. Clinical, hematological parameters and radiological features extracted by CT were considered individually and in combination. All clinical parameters showed statistically significant differences (p < 0.05) for the Kruskal−Wallis test when discriminating both the tumor grading and the metastatic lymph nodes. DOI, PLR, SII, and SIRI showed an accuracy of 0.70 (ROC analysis) when identifying the tumor grading, while an accuracy ≥ 0.78 was shown by DOI, NLR, PLR, SII, and SIRI when discriminating metastatic lymph nodes. In the context of the analysis of radiomics metrics, the original_glszm_HighGrayLevelZoneEmphasis feature was selected for identifying the tumor grading (accuracy of 0.70), while the wavelet_HHH_glrlm_LowGrayLevelRunEmphasis predictor was selected for determining metastatic lymph nodes (accuracy of 0.96). Remarkable findings were also obtained when classifying patients with a machine learning approach. Radiomics features alone can predict tumor grading with an accuracy of 0.76 using a logistic regression model, while an accuracy of 0.82 can be obtained by running a CART algorithm through a combination of three clinical parameters (SIRI, DOI, and PLR) with a radiomics feature (wavelet_LLL_glszm_SizeZoneNonUniformityNormalized). In the context of predicting metastatic lymph nodes, an accuracy of 0.94 was obtained using 15 radiomics features in a logistic regression model, while both CART and CIDT achieved an asymptotic accuracy value of 1.00 using only one radiomics feature. Radiomics features and clinical parameters have an important role in identifying tumor grading and metastatic lymph nodes. Machine learning approaches can be used as an easy-to-use tool to stratify patients with early-stage OTSCC, based on the identification of metastatic and non-metastatic lymph nodes.
- Published
- 2022
16. Management of Orbital Floor Fractures: Our Experience in 10 Years
- Author
-
Pasquale Piombino, Stefania Troise, Fabio Maglitto, Simona Barone, Lorenzo Sani, Umberto Committeri, Giovanna Norino, Paola Bonavolontà, Giovanni Salzano, Luigi Angelo Vaira, Giacomo De Riu, Luigi Califano, Piombino, P., Troise, S., Maglitto, F., Barone, S., Sani, L., Committeri, U., Norino, G., Bonavolonta, P., Salzano, G., Vaira, L. A., De Riu, G., and Califano, L.
- Subjects
Otorhinolaryngology ,Surgery - Abstract
Orbital floor Fractures are the most common fractures involving the facial skeleton and usually occurs after traumatic events. The reconstruction of the orbital floor can be performed with different biocompatible materials. The aim of our retrospective study is to analyze the short- and long-term outcomes of surgically treated patients based on the material used to repair the orbital floor.We enrolled 146 patients hospitalized for orbital floor fractures in the Maxillofacial Surgery Unit of the Federico II University of Naples from 1 to 2010 to July 2020. All the fractured orbital floors were reconstructed with non-resorbable (Titanium Mesh, SynPor, SuPor and MedPor implants) or resorbable (collagen membrane, bovinum pericardium membrane, autologous bone graft) materials.We utilized non-resorbable materials in 56% (82 cases) and resorbable implants in 44% (64 cases). An improvement of the preoperative symptomatology and an aesthetical good outcome was achieved in most cases.Data obtained supports that both resorbable and non-resorbable materials for orbital floor reconstruction are a safe and effective alternatives and offer satisfactory results in functional and aesthetic evaluations.
- Published
- 2022
17. Virtual Surgical Planning and the 'In-House' Rapid Prototyping Technique in Maxillofacial Surgery: The Current Situation and Future Perspectives
- Author
-
Vincenzo Abbate, Pasquale Piombino, Luigi Califano, Giovanni Salzano, Luigi Angelo Vaira, Paola Bonavolontà, Fabio Maglitto, Gianluca Renato De Fazio, Giovanni Dell'Aversana Orabona, Umberto Committeri, Maglitto, F., Dell'Aversana Orabona, G., Committeri, U., Salzano, G., De Fazio, G. R., Vaira, L. A., Abbate, V., Bonavolonta, P., Piombino, P., and Califano, L.
- Subjects
Rapid prototyping ,medicine.medical_specialty ,Reconstructive surgery ,3D-printing ,Computer science ,Radiography ,Traumatology ,CAD ,virtual surgical planning ,maxillofacial surgery ,Surgical planning ,lcsh:Technology ,CAD/CAM ,lcsh:Chemistry ,03 medical and health sciences ,0302 clinical medicine ,Software ,medicine ,General Materials Science ,Instrumentation ,lcsh:QH301-705.5 ,Fluid Flow and Transfer Processes ,business.industry ,lcsh:T ,Process Chemistry and Technology ,General Engineering ,030206 dentistry ,lcsh:QC1-999 ,Computer Science Applications ,Surgery ,medicine.anatomical_structure ,lcsh:Biology (General) ,lcsh:QD1-999 ,lcsh:TA1-2040 ,030220 oncology & carcinogenesis ,Zygomatic arch ,business ,lcsh:Engineering (General). Civil engineering (General) ,lcsh:Physics - Abstract
Background: The first applications of computer-aided design/computer-aided manufacturing (CAD/CAM) in maxillofacial surgery date back to the 1980s. Since then, virtual surgical planning (VSP) has undergone significant development and is now routinely used in daily practice. Indeed, in an extraordinary period, such as that of the current COVID-19 pandemic, it offers a valuable tool in relation to the protection of healthcare workers. In this paper we provide a comprehensive summary of the clinical applications reported in the literature and review our experience using an in-house rapid prototyping technique in the field of maxillofacial surgery. methods: Our research was focused on reconstructive surgery, traumatology (especially in relation to orbital floor and zygomatic arch fractures), and COVID-19 masks. The first step was a radiographic study. Next, computed tomography (CT) scans were segmented in order to obtain a three-dimensional (3D) model. Finally, in the editing phase, through the use of specific software, a customized device for each patient was designed and printed. results: Four reconstructive procedures were performed with a perfect fitting of the surgical device produced by means of VSP. In nine orbital floor fracture cases a good overlapping of the mesh on the orbital floor was obtained. In sixteen zygomatic arch cases the post-operative CT scan showed an excellent fitting of the device and a correct fracture reduction. Regarding the COVID-19 period, six masks and shields produced proved to provide effective protection. conclusions: The timescale and costs required for the production of our &ldquo, home-made&rdquo, virtual design are low, which makes this method applicable to a large number of cases, for both ordinary and extraordinary activities.
- Published
- 2021
- Full Text
- View/download PDF
18. In Reference to Distinct Histopathology Characteristics in Empty Nose Syndrome
- Author
-
Luigi Angelo Vaira, Giacomo De Riu, Francesco Antonio Salzano, Fabio Maglitto, Massimo Mesolella, Salzano, F. A., Vaira, L. A., Maglitto, F., Mesolella, M., and De Riu, G.
- Subjects
medicine.medical_specialty ,business.industry ,empty nose syndrome ,Turbinates ,Anatomy ,Nose ,medicine.disease ,medicine.anatomical_structure ,Otorhinolaryngology ,medicine ,Empty nose syndrome ,Humans ,Histopathology ,business - Published
- 2021
- Full Text
- View/download PDF
19. Obstructive sleep apnoea/hypopnoea syndrome: relationship with obesity and management in obese patients
- Author
-
Francesco Antonio Salzano, Matteo Cavaliere, Massimo Mesolella, Fabio Maglitto, Arianna Di Stadio, Giacomo De Riu, Antonella Bisogno, Giovanni Salzano, Luigi Angelo Vaira, Luigi Califano, Gaetano Motta, Franco Ionna, Salzano, G., Maglitto, F., Bisogno, A., Vaira, L. A., De Riu, G., Cavaliere, M., Di Stadio, A., Mesolella, M., Motta, G., Ionna, F., Califano, L., and Salzano, F. A.
- Subjects
medicine.medical_specialty ,obesity ,chirurgia ortognatica ,Review ,orthognatic surgery ,03 medical and health sciences ,OSAHS ,0302 clinical medicine ,CPAP ,Medicine ,Humans ,030223 otorhinolaryngology ,Gynecology ,OSAHS, obesity, CPAP, pharyngoplasty, orthognatic surgery ,Sleep Apnea, Obstructive ,business.industry ,pharyngoplasty ,obesità ,respiratory tract diseases ,General Energy ,faringoplastica ,Otorhinolaryngology ,030220 oncology & carcinogenesis ,business ,Mandibular Advancement ,Human - Abstract
La sindrome da apnee notturne: correlazione con l’obesità e gestione del paziente obeso.La sindrome da apnee notturne è una malattia caratterizzata da ostruzione delle vie aeree superiori durante il sonno, abbastanza frequente nella popolazione generale, anche se sottovalutata. Russamenti, apnee notturne e ipersonnia diurna sono comuni in questi pazienti. L’obesità svolge un ruolo chiave: riduce le dimensioni e modifica la conformazione delle vie aeree superiori, oltre a prevenire l’espansione polmonare, con conseguente riduzione dei volumi polmonari. Le persone obese sono anche resistenti alla leptina, che stimola fisiologicamente la ventilazione; di conseguenza, questo provoca uno scarso risveglio durante l’apnea. La diagnosi si basa sulla combinazione di parametri clinici, come indice di apnea / ipopnea (AHI), anamnesi, valutazione clinica e Mallampati score. La prima indagine strumentale per identificare pazienti OSAHS è la polisonnografia seguita dalla sleep endoscopy. La terapia prevede in primo luogo la riduzione del peso corporeo, seguita dalla ventilazione a pressione positiva continua delle vie aeree (CPAP), che rimane ancora ad oggi il trattamento di scelta nella maggior parte dei pazienti, dispositivi di avanzamento mandibolare (MAD) e infine diversi approcci chirurgici. Tra le tecniche chirurgiche la faringoplastica (BRP), rappresenta la tecnica prescelta.Obstructive sleep apnoea/hypopnoea syndrome (OSAHS) is a disease characterised by upper airway obstruction during sleep, quite frequent in the general population, even if underestimated. Snoring, sleep apnoea and diurnal hypersomnia are common in these patients. Central obesity plays a key role: it reduces the size and changes the conformation of the upper airways, besides preventing lung expansion, with consequent reduction of lung volumes. Furthermore, obese people are also resistant to leptin, which physiologically stimulates ventilation; as a result, this causes scarce awakening during apnoea. OSAHS diagnosis is based on the combination of clinical parameters, such as apnoea/hypopnoea index (AHI), medical history, physical examination and Mallampati score. The first objective reference method to identify OSAHS is polysomnography followed by sleep endoscopy. Therapy provides in the first instance reduction of body weight, followed by continuous positive airway pressure (CPAP), which still remains the treatment of choice in most patients, mandibular advancement devices (MAD) and finally otolaryngology or maxillofacial surgery. Among surgical techniques, central is barbed reposition pharyngoplasty (BRP), used in the field of multilevel surgery.
- Published
- 2020
20. A Comparative Study of Different Administrations of Nebulized Hyaluronic Acid After Endoscopic Endonasal Surgery for Chronic Rhinosinusitis
- Author
-
Giovanni Improta, Vincenzo Abbate, Paola Bonavolontà, Giorgio Iaconetta, Giovanni Dell'Aversana Orabona, Francesco Seidita, Antonio Romano, Luigi Califano, Fabio Maglitto, Abbate, V., Iaconetta, G., Maglitto, F., Improta, G., Romano, A., Bonavolontà, P., Seidita, F, Califano, L., and Dell’Aversana Orabona, G.
- Subjects
medicine.medical_specialty ,Endoscopic endonasal surgery ,business.industry ,Chronic rhinosinusitis ,medicine.medical_treatment ,Surgery ,Clinical trial ,03 medical and health sciences ,chemistry.chemical_compound ,0302 clinical medicine ,Otorhinolaryngology ,Nasal spray ,chemistry ,030220 oncology & carcinogenesis ,Hyaluronic acid ,Medicine ,Nasal administration ,Hyaluronic acid Nasal douche FESS ESS SNOT-22 Nasal spray ,030223 otorhinolaryngology ,business ,Patient compliance - Abstract
Hyaluronic Acid (HA) plays many roles in wound healing in general, through different mechanisms. Several authors reported the effectiveness of hyaluronic acid in promoting mucosal healing and reducing discomfort for patients after endoscopic sinus surgery (ESS). Different methods for HA nasal administration have been reported. The aim of our study has been to evaluate the efficacy of the administration of nebulized HA through a nasal douche compared with its administration through a nasal spray with patients undergoing ESS for chronic rhinosinusitis. From January 2013 to January 2019 a prospective clinical trial was carried out in our hospital with 163 patients who had undergone ESS for chronic rhinosinusitis. The sample was divided into three groups according to the method of administration of HA. Our study confirm the efficacy of the administration of nebulized HA through nasal douche in post-operative care (6.5% vs 4.5%). The most relevant data regards the nasal dryness sign: the data revealed an unexpected percentage of worsening of that sign at time T3 (p = 0.049) particularly evident in the patients treated with HA through nasal douche compared to whom the nasal spray device was prescribed (4% vs 1%). Further studies are needed to identify the best means of administration of HA, which would satisfy the requirements for efficacy in terms of the results and, at the same time, patient compliance.
- Published
- 2020
21. Syngnathia: A rare case of maxillo-mandibular fusion in an adult patient
- Author
-
Paola Bonavolontà, Giovanni Salzano, Fabio Maglitto, Giorgio Iaconetta, Luigi Califano, Marco Friscia, Umberto Committeri, Antonio Arena, Friscia, M., Bonavolonta, P., Arena, A., Committeri, U., Maglitto, F., Salzano, G., Iaconetta, G., and Califano, L.
- Subjects
Orthodontics ,business.industry ,Temporal bone ,Mandible ,Syngnathia ,Temporomandibular ankylosis ,Cleft palate ,Maxilla ,Rare case ,Medicine ,Surgery ,business - Abstract
Syngnathia is a congenital bony fusion of the mandible to maxilla involving the pediatric age. it is a rare condition that may comprise soft tissue or hard tissues. according to the literature, to our knowledge, 29 cases have been reported during childhood. This clinical condition is usually discovered immediately after birth, since the child is not able to open the mouth, and is unable to feed himself adequately. generally the surgical treatment consists of multiple procedures to release bony fusion, or debride adhesions during the first few days of life. When the lock involves only the soft tissue, the treatment consists in removal the mucosal synechia, by performing an intraoral approach. To our knowledge, herein we describe the first case of unilateral syngnathia in adulthood. A 27-year-old African male was referred to our Department of Maxillo-Facial Surgery of the Federico ii university of Naples in January 2008. The patient reported to have been victim of a direct trauma to the face as a result of an assault when he was child, during the second civil war in Sudan. he was hit with a blunt instrument on the right maxillo-zygomatic region. in conclusion, as far as we know, this is the older patient affected by syngnathia with a suspicion of traumatic etiology, and none of the patients reported in the literature had a traumatic etiology.
- Published
- 2020
22. Adenoid cystic carcinoma of accessory parotid gland: A case report and review of the literature
- Author
-
Umberto Committeri, Carmelo Lo Faro, Fabio Maglitto, Antonio Romano, Giovanni Audino, Giovanni Dell'Aversana Orabona, Giorgio Iaconetta, Giovanni Salzano, Luigi Califano, Romano, A., Lo Faro, C., Iaconetta, G., Committeri, U., Audino, G., Salzano, G., Maglitto, F., Califano, L., and Dell'aversana Orabona, G.
- Subjects
medicine.medical_specialty ,Adenoid cystic carcinoma ,Accessory parotid gland ,lcsh:Surgery ,Postoperative recovery ,03 medical and health sciences ,0302 clinical medicine ,Salivary Gland Tissue ,stomatognathic system ,Mid-cheek mass ,Malignancies ,Salivary glands tumors ,Surgical treatment ,Medicine ,business.industry ,030206 dentistry ,lcsh:RD1-811 ,medicine.disease ,Parotid gland ,stomatognathic diseases ,medicine.anatomical_structure ,Otorhinolaryngology ,030220 oncology & carcinogenesis ,Surgery ,Surgical excision ,Radiology ,Oral Surgery ,business - Abstract
Accessory parotid gland (APG) is a small salivary gland tissue ranging from 0.5 to 1 cm diameter in size, located almost 7 mm anterior to the main parotid gland. APG is a common anatomical variant, but accessory parotid gland tumors are very rare, accounting for only 1%–7.7% of all parotid gland tumors. We present a case of adenoid cystic carcinoma involving accessory parotid gland, a very rare condition with only, to the best of our knowledge, other 7 cases described in literature. Surgical excision was performed and eventful postoperative recovery, without severe surgical complications and no signs of recurrence at 12 months of follow-up was obtained, with a good cosmetic result. An extensive review of the literature has been performed and the results are presented in order to establish a correct diagnostic-therapeutic protocol for these oncologic patients.
- Published
- 2020
23. Postoperative Management of Zygomatic Arch Fractures: In-House Rapid Prototyping System for the Manufacture of Protective Facial Shields
- Author
-
Fabio Maglitto, Giovanni Improta, Vincenzo Abbate, Luigi Califano, Paola Bonavolontà, Giovanni Dell'Aversana Orabona, Alfonso Reccia, Giorgio Iaconetta, Teresa Somma, Umberto Committeri, DELL'AVERSANA ORABONA, Giovanni, Abbate, V., Maglitto, F., Committeri, U., Improta, G., Bonavolonta, P., Reccia, A., Somma, T., Iaconetta, G., and Califano, L.
- Subjects
Facial trauma ,Rapid prototyping ,Adult ,Male ,Arch fracture ,Time Factors ,CAD-CAM ,in house ,rapid prototyping ,zygoma fracture ,Face ,Humans ,Middle Aged ,Young Adult ,Zygoma ,Zygomatic Fractures ,Postoperative Care ,Protective Devices ,Bone healing ,Facial Bones ,Postoperative management ,03 medical and health sciences ,Fixation (surgical) ,0302 clinical medicine ,Medicine ,030223 otorhinolaryngology ,Orthodontics ,Skull Fractures ,business.industry ,Zygoma fracture ,030206 dentistry ,General Medicine ,medicine.disease ,medicine.anatomical_structure ,Otorhinolaryngology ,Surgery ,Zygomatic arch ,business - Abstract
Zygomatic fractures account for 10% to 15% of all facial fractures. The surgical management of isolated zygomatic arch fractures usually requires open reduction treatment without fixation through an intraoral access. Therefore, the main problem in the non-fixed treatment of zygomatic arch fractures is related to the difficulty in obtaining a stable reduction for a period long enough to guarantee the physiological bone healing process. We propose an innovative "in-house" rapid prototyping (RP) protocol for the 3D-zygoma mask manufacture of a patient-specific protective device to apply after zygomatic arch fracture reduction. Our study includes 16 consecutive patients who underwent surgical open reduction for an isolated zygoma fracture without fixation between January 2017 and February 2018. The patients received regular postoperative checks at weeks 1 and 2. Before the device was removed, a multiple choice questionnaire was administered to measure the degree of wearability of the mask. The estimated cost of the production is around &OV0556;5 per case and the construction time is around 90 minutes. Based on the encouraging results, obtained in our experience, we hope that other studies can be conducted to confirm our procedure and improve its functionality in the field of facial trauma.
- Published
- 2019
24. Postoperative complications after removal of pleomorphic adenoma from the parotid gland: A long-term follow up of 297 patients from 2002 to 2016 and a review of publications
- Author
-
Vincenzo Abbate, Luigi Califano, Umberto Committeri, Giorgio Iaconetta, Giovanni Dell'Aversana Orabona, Fabio Maglitto, Giovanni Improta, Giovanni Salzano, Paola Bonavolontà, Bonavolonta, P., Dell'Aversana Orabona, G., Maglitto, F., Abbate, V., Committeri, U., Salzano, G., Improta, G., Iaconetta, G., and Califano, L.
- Subjects
Male ,Adenoma ,pleomorphic adenoma ,medicine.medical_specialty ,Adenoma, Pleomorphic ,Pleomorphic ,Malignancy ,superficial parotidectomy ,Pleomorphic adenoma ,03 medical and health sciences ,Postoperative Complications ,0302 clinical medicine ,extracapsular dissection ,Statistical significance ,medicine ,Humans ,Parotid Gland ,030223 otorhinolaryngology ,Retrospective Studies ,business.industry ,Retrospective cohort study ,030206 dentistry ,medicine.disease ,Female ,Follow-Up Studies ,Neoplasm Recurrence, Local ,Parotid Neoplasms ,Facial paralysis ,Surgery ,Parotid gland ,stomatognathic diseases ,Neoplasm Recurrence ,medicine.anatomical_structure ,Carcinoma ex pleomorphic adenoma ,Local ,Otorhinolaryngology ,Superficial Parotidectomy ,Oral Surgery ,business - Abstract
Pleomorphic adenomas are rounded, lumpy, capsulated lesions that are more common in women. They are typically benign, but can be associated with malignancy in a minority of cases (such as carcinoma ex pleomorphic adenoma), between 3% - 12% of the time, according to available data. The purpose of our study was to evaluate clinical outcomes in patients with benign parotid gland tumours after extracapsular dissection (ECD) or superficial parotidectomy (SP). We made a retrospective study of 297 patients who had had benign tumours of the parotid gland, and had been referred to our department from 2002 - 2016 to have either procedure. We measured the statistical differences between the two techniques (evaluated recurrence rate and complications) with the chi squared test. The chosen level of statistical significance was p
- Published
- 2019
25. Quantitative assessment of dimensional evolution of solitary osteoma of the mandible through 14 years of radiographic follow-up analysis: A unique case report
- Author
-
Giovanni Salzano, Francesco Perri, Umberto Committeri, Agostino Guida, Marco Annunziata, M.G. Maglione, Fabio Maglitto, Franco Ionna, Costantino Maietta, Maglitto, F., Committeri, U., Salzano, G., Maietta, C., Annunziata, M., Maglione, M. G., Perri, F., Ionna, F., Guida, A., Maglitto, Fabio, Committeri, Umberto, Salzano, Giovanni, Maietta, Costantino, Annunziata, Marco, Grazia Maglione, Maria, Perri, Francesco, Ionna, Franco, and Guida, Agostino
- Subjects
medicine.medical_specialty ,RD1-811 ,Radiographic imaging ,Radiography ,Computed tomography ,Mandible ,03 medical and health sciences ,0302 clinical medicine ,Quantitative assessment ,medicine ,Osteoma ,medicine.diagnostic_test ,business.industry ,030206 dentistry ,medicine.disease ,Otorhinolaryngology ,030220 oncology & carcinogenesis ,Solitary ,Surgery ,Radiology ,Oral Surgery ,business ,Sigmoid notch ,Mandibular ramus - Abstract
Head & Neck Osteomas are extremely rare osteogenic benign tumors, with unclear pathogenesis and heterogeneous clinical behavior. There are no studies in literature showing the characteristics of dimensional growth of such lesions. We report a case of a peripheral solitary osteoma of the sigmoid notch of the mandibular ramus, describing its radiographic growth in fourteen years. Measurements from OPTs (2003–6x7mm, 2008–8x12mm, 2014–17 × 24mm, 2016–19 × 25mm and 2017–21 × 28mm) and 3d cone-beam computed tomography scan (2016–19 × 15 × 21mm, 2017–21,4 × 19,2 × 22,7) were obtained. The growth of the lesion measured on OPTs was in mean 1.1 × 1.5 mm per year. This is the first case report in literature quantitatively assessing the growth of a solitary osteoma of the mandible through radiographic imaging, which seems to be more than 1 mm per dimension per year.
- Published
- 2021
- Full Text
- View/download PDF
26. Odontogenic lesion mimicking squamous cell carcinoma: A new histological entity?
- Author
-
Mariarosaria Cervasio, Giorgio Iaconetta, Ludovica Marcella Ponzo, Luigi Califano, Antonio Pansini, Fabio Maglitto, Giovanni Salzano, Giovanni Dell'Aversana Orabona, Dell'Aversana Orabona, G, Salzano, G, Ponzo L., M, Maglitto, F, Pansini, A, Cervasio, M, Iaconetta, G, and Califano, L.
- Subjects
Pathology ,medicine.medical_specialty ,business.industry ,Otorhinolaryngology2734 Pathology and Forensic Medicine ,Surgery ,Oral Surgery ,Odontogenic ,Lesion ,Otorhinolaryngology ,medicine ,Basal cell ,medicine.symptom ,business - Published
- 2018
27. Erratum to: Surgical evolution in the treatment of mandibular condyle fractures
- Author
-
Pasquale Piombino, Giacomo De Riu, Giovanni Dell'Aversana Orabona, E. Mici, Fabio Maglitto, Evaristo Belli, Luciano Catalfamo, Gianmauro Liberatore, Belli, E., Liberatore, G., Mici, E., Orabona, G. D., Piombino, P., Maglitto, F., Catalfamo, L., and De Riu, G.
- Subjects
Adult ,Male ,medicine.medical_specialty ,Adolescent ,External Fixators ,Condyle ,Young Adult ,Fracture Fixation ,Mandibular Fractures ,Medicine ,Humans ,Maxillofacial surgery department ,Child ,business.industry ,General surgery ,Mandibular Condyle ,Endoscopy ,General Medicine ,Middle Aged ,University hospital ,Surgery ,Treatment Outcome ,Female ,Erratum ,business - Abstract
In Literature fractures of the mandible that involve the condyle ranges from 20% to 35% and various possible surgical options are described according to the varying pathological situations. Up to the present, numerous techniques have been used for the surgical treatment of condylar fractures. In this article we are proposing the combination of two surgical techniques as therapy for extra-capsular condylar fractures with dislocation.From June 2003 to July 2007 30 patients were treated for condylar fractures with the application of a Rigid External Fixator under endoscopic assistance. This method includes a surgical reduction of the fracture with the aid of an endoscope, performing a transcutaneous insertion of a Rigid External Fixator to stabilize the fracture.Out of the total number of patients, 28 reached an optimal result without the need for temporary immobilization of the temporal mandibular joint and pre-auricular cutaneous access, thanks to the decisive aid of the video-endoscope.The endoscope allows perfect control over both the positioning of the external fixator and the surgical reduction, restoring the normal movement of the mandible with a return to full anatomical functioning of the temporo-mandibular joint. This approach avoids possible damages to the facial nerve branches. The rigid external fixation system is better than an internal one, because it is less restrictive in precise anatomical reduction, since with an REF the condylar fragment is kept in the correct anatomical position but is not obliged to maintain that exact position, and therefore it is possible to carry out all the repair mechanisms listed above. Endoscopic assistance allows a good positioning control of the REF although the endoscopy permits an optimal control of the condylemeniscal complex mobility after REF application.
- Published
- 2015
28. A rare isolated unilateral myositis ossificans traumatica of the lateral pterygoid muscle: a case report
- Author
-
Fabio Maglitto, Guido Moscato, Emanuele Broccardo, Pasquale Piombino, Alessia Spinzia, Giovanni Dell'Aversana Orabona, Lara Castelletti, Spinzia, Alessia, Moscato, Guido, Broccardo, Emanuele, Castelletti, Lara, Maglitto, Fabio, Orabona, Giovanni Dell'Aversana, Piombino, Pasquale, Spinzia, A, Moscato, G, Broccardo, E, Castelletti, L, Maglitto, F, DELL'AVERSANA ORABONA, Giovanni, and Piombino, P.
- Subjects
Adult ,Male ,Myositis Ossifican ,Myositis ossificans traumatica ,medicine.medical_specialty ,Lateral pterygoid muscle ,Physiotherapy treatment ,Case Report ,Trismus ,Temporo mandibular joint disorders ,Pterygoid Muscle ,stomatognathic system ,Temporo mandibular joint disorder ,Physical Therapy Modalitie ,medicine ,Humans ,Pathological ,Physical Therapy Modalities ,Trismu ,Medicine(all) ,Skull Fractures ,business.industry ,Medicine (all) ,Pterygoid Muscles ,General Medicine ,Myositis ossificans ,medicine.disease ,Surgery ,Skull Fracture ,Myositis Ossificans ,medicine.symptom ,Complication ,business ,Tomography, X-Ray Computed ,Calcification ,Human - Abstract
Introduction. Myositis ossificans traumatica is a pathological condition characterized by the extraskeletal formation of bony tissue, induced by violent or repeated trauma. Case presentation. A 30-year-old Italian man, after surgical treatment for multiple facial fractures, presented with a progressive limitation of mouth opening. A computed tomography scan showed a significant calcification of the fibers of the left lateral pterygoid muscle. The working diagnosis was myositis ossificans traumatica of the left lateral pterygoid muscle. Surgical excision was suggested but not performed. Our patient underwent physiotherapy treatment resulting not in a complete restoration of mandibular movements but in an acceptable recovery of mouth opening. Conclusions: Myositis ossificans is a rare complication that can be caused by muscle trauma. Therefore, special attention should be paid to surgical trauma. In the present case, surgical excision was considered, in accordance with the literature, and suggested to our patient, but he declined due to the absence of any pain or any significant limitation to his daily life activities. He therefore underwent physiotherapy treatment, in line with our unit's guidelines, resulting not in a complete restoration of mandibular movements but in an acceptable recovery of mouth opening. © 2014 Spinzia et al.; licensee BioMed Central Ltd.
- Full Text
- View/download PDF
29. Nodal assessment and extranodal extension in head and neck squamous cell cancer: insights from computed tomography and magnetic resonance imaging.
- Author
-
Maggialetti N, Villanova I, Greco S, Sardaro A, Lagrasta MT, Dipalma C, Maglitto F, Bicci E, Lucarelli NM, Copelli C, and Ianora AAS
- Abstract
Purpose: The aim of the study was to evaluate the concordance between computed tomography (CT)/magnetic resonance imaging (MRI) and histological examination in the evaluation of lymph nodal involvement (N+) and extranodal extension (ENE+) in patients with squamous cell cancer of the head-neck district (HNSCC). The second end point was to evaluate which of the imaging features was more sensitive and specific in establishing N+ and ENE+, and comparing the diagnostic accuracy between CT and MRI., Material and Methods: 58 patients with HNSCC undergoing surgical treatment with lymph node dissection at the Policlinico of Bari were enrolled in this retrospective study. The criteria used for identifying radiological N+ (rN+) included six characteristics; the presence of any two or more criteria out of these six was considered rN+. For each rN+, the radiological extranodal extension (rENE+) was evaluated analyzing three characteristics; rENE was considered positive if any one criterion was present., Results: Of 167 lymph nodes, 45/167 (27%) had rN+, out of which 20/45 (44%) were rENE+. On pathological examination, 38/45 (84%) nodes were N+ and 11/20 (55%) were ENE+. The agreement between imaging and histology in the evaluation of N was (149/167) 89% with a good concordance (k = 0.7). The agreement between imaging and histology in the evaluation of ENE was (35/45) 78% with a moderate concordance (k = 0.5). Loss of fatty hilum was found to be the most sensitive (84%) imaging finding in N+ evaluation. Capsular irregularity with fat stranding had the highest sensitivity (82%) for the determination of ENE+. Comparing CT and MRI imaging in the evaluation of N+ and ENE+, we found no statistically significant differences (p-value of 0.3 for N+ and p-value of 0.3 for ENE +)., Conclusions: Imaging has good confidence in detecting rN+ but modest in assessing rENE+. Further research could improve the imaging specificity for the determination of rENE., Competing Interests: Declarations. Conflict of interest: The authors have no relevant financial or non-financial interests to disclose. Ethics approval: The present retrospective clinical study was conducted at the University of Bari (Italy), in full accordance with ethical principles, including the World Medical Association Declaration of Helsinki and the additional requirements of Italian law. Furthermore, the University of Bari, Italy, classified the study as being exempt from ethical review as it carries only negligible risk and involves the use of existing data that contain only non-identifiable information about human beings. The patients signed a written informed consent form. Consent to participate: The patients signed a written informed consent form., (© 2024. Italian Society of Medical Radiology.)
- Published
- 2024
- Full Text
- View/download PDF
30. Validation of the Quality Analysis of Medical Artificial Intelligence (QAMAI) tool: a new tool to assess the quality of health information provided by AI platforms.
- Author
-
Vaira LA, Lechien JR, Abbate V, Allevi F, Audino G, Beltramini GA, Bergonzani M, Boscolo-Rizzo P, Califano G, Cammaroto G, Chiesa-Estomba CM, Committeri U, Crimi S, Curran NR, di Bello F, di Stadio A, Frosolini A, Gabriele G, Gengler IM, Lonardi F, Maglitto F, Mayo-Yáñez M, Petrocelli M, Pucci R, Saibene AM, Saponaro G, Tel A, Trabalzini F, Trecca EMC, Vellone V, Salzano G, and De Riu G
- Subjects
- Humans, Reproducibility of Results, Surveys and Questionnaires, Artificial Intelligence
- Abstract
Background: The widespread diffusion of Artificial Intelligence (AI) platforms is revolutionizing how health-related information is disseminated, thereby highlighting the need for tools to evaluate the quality of such information. This study aimed to propose and validate the Quality Assessment of Medical Artificial Intelligence (QAMAI), a tool specifically designed to assess the quality of health information provided by AI platforms., Methods: The QAMAI tool has been developed by a panel of experts following guidelines for the development of new questionnaires. A total of 30 responses from ChatGPT4, addressing patient queries, theoretical questions, and clinical head and neck surgery scenarios were assessed by 27 reviewers from 25 academic centers worldwide. Construct validity, internal consistency, inter-rater and test-retest reliability were assessed to validate the tool., Results: The validation was conducted on the basis of 792 assessments for the 30 responses given by ChatGPT4. The results of the exploratory factor analysis revealed a unidimensional structure of the QAMAI with a single factor comprising all the items that explained 51.1% of the variance with factor loadings ranging from 0.449 to 0.856. Overall internal consistency was high (Cronbach's alpha = 0.837). The Interclass Correlation Coefficient was 0.983 (95% CI 0.973-0.991; F (29,542) = 68.3; p < 0.001), indicating excellent reliability. Test-retest reliability analysis revealed a moderate-to-strong correlation with a Pearson's coefficient of 0.876 (95% CI 0.859-0.891; p < 0.001)., Conclusions: The QAMAI tool demonstrated significant reliability and validity in assessing the quality of health information provided by AI platforms. Such a tool might become particularly important/useful for physicians as patients increasingly seek medical information on AI platforms., (© 2024. The Author(s).)
- Published
- 2024
- Full Text
- View/download PDF
31. Evaluating AI-Generated informed consent documents in oral surgery: A comparative study of ChatGPT-4, Bard gemini advanced, and human-written consents.
- Author
-
Vaira LA, Lechien JR, Maniaci A, Tanda G, Abbate V, Allevi F, Arena A, Beltramini GA, Bergonzani M, Bolzoni AR, Crimi S, Frosolini A, Gabriele G, Maglitto F, Mayo-Yáñez M, Orrù L, Petrocelli M, Pucci R, Saibene AM, Troise S, Tel A, Vellone V, Chiesa-Estomba CM, Boscolo-Rizzo P, Salzano G, and De Riu G
- Abstract
This study evaluates the quality and readability of informed consent documents generated by AI platforms ChatGPT-4 and Bard Gemini Advanced compared to those written by a first-year oral surgery resident for common oral surgery procedures. The evaluation, conducted by 18 experienced oral and maxillofacial surgeons, assessed consents for accuracy, completeness, readability, and overall quality. ChatGPT-4 consistently outperformed both Bard and human-written consents. ChatGPT-4 consents had a median accuracy score of 4 [IQR 4-4], compared to Bard's 3 [IQR 3-4] and human's 4 [IQR 3-4]. Completeness scores were higher for ChatGPT-4 (4 [IQR 4-5]) than Bard (3 [IQR 3-4]) and human (4 [IQR 3-4]). Readability was also superior for ChatGPT-4, with a median score of 4 [IQR 4-5] compared to Bard and human consents, both at 4 [IQR 4-4] and 4 [IQR 3-4], respectively. The Gunning Fog Index for ChatGPT-4 was 17.2 [IQR 16.5-18.2], better than Bard's 23.1 [IQR 20.5-24.7] and the human consents' 20 [IQR 19.2-20.9]. Overall, ChatGPT-4's consents received the highest quality ratings, underscoring AI's potential in enhancing patient communication and the informed consent process. The study suggests AI can reduce misinformation risks and improve patient understanding, but continuous evaluation, oversight, and patient feedback integration are crucial to ensure the effectiveness and appropriateness of AI-generated content in clinical practice., Competing Interests: Declaration of competing interest All authors report no conflict of interest., (Copyright © 2024 The Authors. Published by Elsevier Ltd.. All rights reserved.)
- Published
- 2024
- Full Text
- View/download PDF
32. The Impact of Standing Electric Scooters on Maxillofacial Fractures: An Italian Multi-Centric Epidemiological Study.
- Author
-
Salzano G, Maffia F, Vaira LA, Fusco R, Albanese M, Crimi S, Cucurullo M, Maglitto F, Maugeri C, Petrocelli M, Pitino F, Priore P, Roccia F, Tel A, Baietti AM, Bianchi A, Biglioli F, Copelli C, De Riu G, Nocini PF, Ramieri G, Robiony M, Valentini V, and Califano L
- Abstract
Objectives : This study aimed to determine the impact of standing electric scooters on maxillofacial on the Italian territory. Methods : The authors analyzed the epidemiology of the injuries to define electric mobility's impact on maxillofacial surgery practice. For this retrospective cohort study, data were collected by unifying the standing e-scooter-related fractures database from 10 Italian maxillofacial surgery departments. The reference period considered was from January 2020 to December 2023. The main data considered included age, gender, type of access, time slot of admission, type of admission, alcohol level, helmet use, dynamics of the accident, and area of the fracture. Results : A total of 79 patients were enrolled. The average age of the participants was approximately 31 years. The blood alcohol level was found to be above the Italian norm in 15 cases (19%). Only one patient wore a helmet. The most affected facial third was the middle one with 36 cases (45.5%), followed by the lower one (31, 39.3%). The most recurrent patterns were fractures of the orbito-malar-zygomatic complex (15, 19%), followed by multifocal (bifocal, trifocal) fractures of the mandible (14, 17.5%). Conclusions : This study demonstrated how maxillofacial fractures related to the use of electric scooters are associated with complex patterns, associated with a high rate of post-surgical aftermaths.
- Published
- 2024
- Full Text
- View/download PDF
33. Correction: Ionna et al. Sentinel Lymph Node Biopsy (SLNB) for Early-Stage Head and Neck Squamous-Cell Carcinoma of the Tongue: Twenty Years of Experience at I.N.T. "G.Pascale". Cancers 2024, 16 , 1153.
- Author
-
Ionna F, Pavone E, Aversa C, Maffia F, Spinelli R, Carraturo E, Salzano G, Maglitto F, Sarcinella M, Fusco R, Granata V, Lastoria S, Prato FD, and Maglione MG
- Abstract
In the published publication [...].
- Published
- 2024
- Full Text
- View/download PDF
34. Special Issue "New Updates in Oral and Maxillofacial Surgery".
- Author
-
Maglitto F, Copelli C, Manfuso A, Cocis S, and Salzano G
- Abstract
In the ever-evolving landscape of medical science, few fields have witnessed as profound a transformation as oral and maxillofacial surgery [...].
- Published
- 2024
- Full Text
- View/download PDF
35. Changes in hospital admissions for facial fractures during and after COVID 19 pandemic: national multicentric epidemiological analysis on 2938 patients.
- Author
-
Petrocelli M, Ruggiero F, Allegri D, Cutrupi S, Baietti AM, Salzano G, Maglitto F, Manfuso A, Copelli C, Barca I, Cristofaro MG, Galvano F, Loche VP, Gemini P, Tewfik K, Burlini D, Bernardi M, Bianchi FA, Catanzaro S, Ascani G, Consorti G, Balercia P, Braconi A, Scozzaro C, Catalfamo L, De Rinaldis D, De Ponte FS, Tarabbia F, Biglioli F, Giovacchini F, Tullio A, Cama A, Di Emidio P, Ferrari S, Perlangeli G, Rossi MB, Biglio A, De Riu G, Califano L, and Vaira LA
- Subjects
- Humans, Italy epidemiology, Male, Female, Retrospective Studies, Middle Aged, Adult, Aged, Adolescent, Young Adult, Facial Bones injuries, Aged, 80 and over, Child, SARS-CoV-2, COVID-19 epidemiology, Skull Fractures epidemiology, Skull Fractures surgery, Pandemics, Hospitalization statistics & numerical data
- Abstract
Purpose: The objective of this multicenter study was to examine the differences in maxillo-facial fractures epidemiology across the various phases of the SARS-CoV-2 pandemic., Methods: This is a retrospective study on patients who underwent surgery for facial bone fractures in 18 maxillo-facial surgery departments in Italy, spanning from June 23, 2019, to February 23, 2022. Based on the admission date, the data were classified into four chronological periods reflecting distinct periods of restrictions in Italy: pre-pandemic, first wave, partial restrictions, and post-pandemic. Epidemiological differences across the groups were analysed., Results: The study included 2938 patients. A statistically significant difference in hospitalization causes was detected between the pre-pandemic and first wave groups (p = 0.005) and between the pre-pandemic and partial restriction groups (p = 0.002). The differences between the pre- and post-pandemic groups were instead not significant (p = 0.106). Compared to the pre-pandemic period, the number of patients of African origin was significantly higher during the first wave and the post-pandemic period. No statistically significant differences were found across the periods concerning gender, age, fracture type, treatment approach, and hospital stay duration CONCLUSIONS: The COVID-19 pandemic brought about significant changes in fracture epidemiology, influenced by the restrictive measures enforced by the government in Italy. Upon the pandemic's conclusion, the fracture epidemiology returned to the patterns observed in the pre-pandemic period., (© 2023. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.)
- Published
- 2024
- Full Text
- View/download PDF
36. Accuracy of ChatGPT-Generated Information on Head and Neck and Oromaxillofacial Surgery: A Multicenter Collaborative Analysis.
- Author
-
Vaira LA, Lechien JR, Abbate V, Allevi F, Audino G, Beltramini GA, Bergonzani M, Bolzoni A, Committeri U, Crimi S, Gabriele G, Lonardi F, Maglitto F, Petrocelli M, Pucci R, Saponaro G, Tel A, Vellone V, Chiesa-Estomba CM, Boscolo-Rizzo P, Salzano G, and De Riu G
- Subjects
- Humans, Italy, Surveys and Questionnaires, Otorhinolaryngologic Surgical Procedures, Artificial Intelligence
- Abstract
Objective: To investigate the accuracy of Chat-Based Generative Pre-trained Transformer (ChatGPT) in answering questions and solving clinical scenarios of head and neck surgery., Study Design: Observational and valuative study., Setting: Eighteen surgeons from 14 Italian head and neck surgery units., Methods: A total of 144 clinical questions encompassing different subspecialities of head and neck surgery and 15 comprehensive clinical scenarios were developed. Questions and scenarios were inputted into ChatGPT4, and the resulting answers were evaluated by the researchers using accuracy (range 1-6), completeness (range 1-3), and references' quality Likert scales., Results: The overall median score of open-ended questions was 6 (interquartile range[IQR]: 5-6) for accuracy and 3 (IQR: 2-3) for completeness. Overall, the reviewers rated the answer as entirely or nearly entirely correct in 87.2% of cases and as comprehensive and covering all aspects of the question in 73% of cases. The artificial intelligence (AI) model achieved a correct response in 84.7% of the closed-ended questions (11 wrong answers). As for the clinical scenarios, ChatGPT provided a fully or nearly fully correct diagnosis in 81.7% of cases. The proposed diagnostic or therapeutic procedure was judged to be complete in 56.7% of cases. The overall quality of the bibliographic references was poor, and sources were nonexistent in 46.4% of the cases., Conclusion: The results generally demonstrate a good level of accuracy in the AI's answers. The AI's ability to resolve complex clinical scenarios is promising, but it still falls short of being considered a reliable support for the decision-making process of specialists in head-neck surgery., (© 2023 The Authors. Otolaryngology–Head and Neck Surgery published by Wiley Periodicals LLC on behalf of American Academy of Otolaryngology–Head and Neck Surgery Foundation.)
- Published
- 2024
- Full Text
- View/download PDF
37. Bone reconstruction using CAD/CAM technology in head and neck surgical oncology. A narrative review of state of the art and aesthetic-functional outcomes.
- Author
-
Copelli C, Cacciatore F, Cocis S, Maglitto F, Barbara F, Iocca O, and Manfuso A
- Subjects
- Humans, Esthetics, Treatment Outcome, Plastic Surgery Procedures methods, Head and Neck Neoplasms surgery, Computer-Aided Design
- Published
- 2024
- Full Text
- View/download PDF
38. Sentinel Lymph Node Biopsy (SLNB) for Early-Stage Head and Neck Squamous-Cell Carcinoma of the Tongue: Twenty Years of Experience at I.N.T. "G.Pascale".
- Author
-
Ionna F, Pavone E, Aversa C, Maffia F, Spinelli R, Carraturo E, Salzano G, Maglitto F, Sarcinella M, Fusco R, Granata V, Lastoria S, Del Prato F, and Maglione MG
- Abstract
Oral tongue squamous-cell carcinoma (OTSCC) is the most prevalent malignancy in the head and neck region. Lymphatic spread, particularly to cervical lymph nodes, significantly impacts 5-year survival rates, emphasizing the criticality of precise staging. Metastatic cervical lymph nodes can decrease survival rates by 50%. Yet, elective neck dissection (END) in T1-2 cN0 patients proves to be an overtreatment in around 80% of cases. To address this, sentinel lymph node biopsy (SLNB) was introduced, aiming to minimize postoperative morbidity. This study, conducted at the ENT and Maxillofacial Surgery department of the Istituto Nazionale Tumori in Naples, explores SLNB's efficacy in early-stage oral tongue squamous-cell carcinoma (OTSCC). From January 2020 to January 2022, 122 T1/T2 cN0 HNSCC patients were enrolled. Radioactive tracers and lymphoscintigraphy identified sentinel lymph nodes, aided by a gamma probe during surgery. Results revealed 24.6% SLN biopsy positivity, with 169 SLNs resected and a 21.9% positivity ratio. The study suggests SLNB's reliability for T1-2 cN0 OTSCC patient staging and early micrometastasis detection.
- Published
- 2024
- Full Text
- View/download PDF
39. Surgical management of Warthin tumor: long-term follow-up of 224 patients from 2002 to 2018.
- Author
-
Bonavolontà P, Germano C, Committeri U, Orabona GD, Piombino P, Abbate V, Maglitto F, Iaconetta G, and Califano L
- Subjects
- Humans, Retrospective Studies, Follow-Up Studies, Postoperative Complications etiology, Postoperative Complications pathology, Paralysis complications, Paralysis pathology, Parotid Gland pathology, Adenolymphoma surgery, Adenolymphoma complications, Adenolymphoma pathology, Sweating, Gustatory etiology, Sweating, Gustatory pathology, Parotid Neoplasms surgery, Parotid Neoplasms pathology
- Abstract
Purpose: Warthin tumors (WT) are the second most common benign parotid gland neoplasms. They can occur as synchronous or metachronous lesions in 6-10% of cases. This study aims to compare the complication rate in 224 patients who underwent extracapsular dissection (ECD) or superficial parotidectomy (SP) for the treatment of a WT., Methods: This retrospective study was conducted at the Department of Maxillo-Facial Surgery at the University of Naples "Federico II" from February 2002 to December 2018 on a group of patients who underwent surgical treatment for WT. The type of surgical technique was chosen based on Quer's classification. The complications evaluated were facial nerve palsy, hematoma, Frey's syndrome, and bleeding., Results: A total of 224 patients treated from 2002 to 2018 for Warthin tumor were included in the study. Two hundred elven had solitary tumors (94.1%) and 13 had multicentric lesions (5.8%), of which 9 cases presented synchronous lesions and 4 cases presented metachronous lesions. Extracapsular dissection (ECD) was performed in 130 patients (58.3% of cases) and superficial parotidectomy (SP) in the other 94 (41.7% of cases)., Conclusions: We consider both surgical techniques as valid. In our opinion, it is essential to study each case based on Quer's Classification to obtain the best surgical outcome. Based on a lower observed rate of complications such as facial nerve palsy, Frey's syndrome, and bleeding, ECD seems to be the best option for the surgical treatment of Quer Class I lesions., (© 2023. The Author(s).)
- Published
- 2024
- Full Text
- View/download PDF
40. Efficacy of auriculotherapy in the control of pain, edema, and trismus following surgical extraction of the lower third molars: a split-mouth, randomized, placebo-controlled, and triple-blind study.
- Author
-
Vaira LA, Massaiu A, Massaiu G, Salzano G, Maglitto F, Lechien JR, Biglio A, Visaloco G, Piombino P, Biglioli F, and De Riu G
- Subjects
- Humans, Molar, Third surgery, Trismus etiology, Trismus prevention & control, Pain, Postoperative etiology, Pain, Postoperative prevention & control, Tooth Extraction adverse effects, Mouth, Edema etiology, Edema prevention & control, Tooth, Impacted surgery, Auriculotherapy
- Abstract
Background: The aim of this split-mouth, randomized, placebo-controlled, and triple-blind study was to evaluate whether auriculotherapy had any effect on the post-operative course after the extraction of third molars in terms of the control of pain, edema, and trismus., Materials and Methods: The study included 42 patients (84 teeth) who had undergone a surgical extraction of the lower third molars. In each patient, the two extractions were randomly assigned to two study groups. In the therapy group, the patients underwent auriculotherapy with vaccaria seeds applied with patches in 6 ear points. In the control group, the patches were applied, without seeds, to the same ear points. After the extraction, the patients were asked to stimulate the ear points three times a day and whenever they felt pain. The patients were asked to keep a diary in which they assessed their pain by means of the Visual Analog Scale (VAS) for 8 days. Edema and trismus were assessed 1, 2, 3, and 8 days after surgery., Results: The differences between the two groups were statistically significant at the 12-h control (auriculotherapy group (AG) VAS 5.5 [IQR 4.25-6.75], placebo group (PG) VAS 6 [IQR 5-8], p = 0.040), after 24 h (AG VAS 5 [IQR 4-6], PG VAS 6 [IQR 4.25-7], p = 0.024), after 2 days (AG VAS 4 [IQR 3-5], PG VAS 4.5 [IQR 4-6], p = 0.044), and after 3 days (AG VAS 3 [IQR 0-5], PG VAS 4 [IQR 3-5], p = 0.024). Throughout the observation period, the AG took a significantly lower number of painkillers than the PG (AG 6 [IQR 4.25-7]; PG 8 [IQR 8-9], p < 0.001). There were no significant differences in the levels of edema and trismus between the two groups throughout the observation period., Conclusions: On the basis of the results of the present study, auriculotherapy can be considered as a cost-effective adjuvant pain reliever treatment in patients undergoing an extraction of the lower third molars., (© 2023. The Author(s).)
- Published
- 2024
- Full Text
- View/download PDF
41. Nebulized hyaluronic acid improves nasal symptoms after orthognathic surgery: a randomized clinical trial.
- Author
-
Bergonzani M, Anghinoni ML, Pedrazzi G, Maglitto F, Varazzani A, Sesenna E, and Ferri A
- Subjects
- Humans, Hyaluronic Acid therapeutic use, Prospective Studies, Quality of Life, Osteotomy, Le Fort, Orthognathic Surgery, Nasal Obstruction drug therapy, Nasal Obstruction surgery
- Abstract
Purpose: After maxillary osteotomy in orthognathic surgery, patients report nasal breathing discomfort in early postoperative period. Topical hyaluronic acid (HA) has been proven to have beneficial effects on the upper airway tract mucosa. This prospective randomized controlled study was designed to analyze the effect on nasal obstruction of nebulized HA during the recovery process after maxillary osteotomy., Methods: Patients were randomized to control and treatment groups. The postoperative treatment differed only for additional nebulized HA provided to the treatment group. The level of nasal obstruction, and its impact on quality of life, was assessed every 3 days for the first 15 days postoperatively using a questionnaire. Demographic and other variables (maxillary osteotomy type and surgical movements) were analyzed. Differences in quantitative data were tested using Student's t-test, the Mann-Whitney U test, and mixed repeated measures ANOVA., Results: Twenty-four subjects were included in each group; differences in age, sex, type of maxillary osteotomy, and movements were non-statistically significative. At the beginning of treatment (T0), the two groups had comparable questionnaire scores regarding nasal breathing discomfort (p >0.05), whereas statistically significant differences were found at days 3, 6, 9, and 12 (p <0.05). A significant decrease in nasal breathing discomfort over time was observed in both groups, with trends that differed between the two, indicating faster improvement in the treatment group., Conclusion: Nebulized HA can be a useful additional treatment in early postoperative period after orthognathic surgery. Patients reported more rapid improvement of nasal respiratory symptoms, indicating a potential role for HA in reducing recovery time and patient discomfort after maxillary surgery., (© 2022. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.)
- Published
- 2023
- Full Text
- View/download PDF
42. Olfactory recovery following omicron variant infection: a psychophysical prospective case-control study with six-month follow up.
- Author
-
Vaira LA, Boscolo-Rizzo P, Lechien JR, Mayo-Yáñez M, Petrocelli M, Pistidda L, Salzano G, Maglitto F, Hopkins C, and De Riu G
- Subjects
- Humans, Case-Control Studies, Follow-Up Studies, Smell, Anosmia etiology, Olfaction Disorders epidemiology, Olfaction Disorders etiology
- Abstract
Objective: This study aimed to evaluate the recovery of olfactory function at six months in individuals infected with the coronavirus disease 2019 omicron variant, using psychophysical tests., Methods: A prospective case-control study that included severe acute respiratory syndrome coronavirus-2 patients infected in February and March 2022 was conducted. Patients underwent the Sniffin' Sticks test within 10 days of infection and again after at least 6 months. The olfactory scores were compared with those of a control group., Results: In all, 102 patients and 120 controls were enrolled in the study. At baseline, 26 patients (25.5 per cent) self-reported smell loss. The median threshold, discrimination and identification score was 33.6 (interquartile range, 12.5) for the cases and 36.5 (interquartile range, 4.38) for the controls ( p < 0.001). Based on the threshold, discrimination and identification scores, 12 controls and 34 patients reported olfactory dysfunction ( p < 0.001). Eighty cases underwent re-evaluation at six months; the median threshold, discrimination and identification score was 37.1 (interquartile range, 4.75) with no significant differences compared with the controls., Conclusion: Six months after infection, the prevalence of olfactory dysfunction in patients did not differ significantly from the control population.
- Published
- 2023
- Full Text
- View/download PDF
43. Pharyngocutaneous Fistula in Salvage Laryngectomy: Use of the Stapler Versus Manual Suturing Technique.
- Author
-
Salzano G, Maglitto F, Calvanese C, Apolito M, Buono S, Franco P, Perri F, Vaira LA, De Luca R, Salzano FA, Califano L, and Ionna F
- Abstract
A pharyngocutaneous fistula (PCF) is the most common complication after salvage total laryngectomy (STL) with an incidence ranging from 5 to 73%, causing an increase in morbidity and delaying the patient's recovery. A surgical technique to prevent PCF formation is the use of the stapler to suture the pharyngeal mucosa. We have reviewed the medical files of 91 patients who had undergone STL, dividing the patients into two groups (manual suture vs. stapler), based on the type of pharyngeal suture performed during the STL. We found 12/49 (24.5%) cases of a PCF in group A (manual) and 5/42 (11.9%) cases of a PCF in group B (stapler). There is a statistically significant difference between the two groups with the patients in group B presenting better results in terms of the reduction of the surgical time, the length of the hospital stay and also in the restarting of oral feeding. The advantages of mechanical suturing with the stapler are reduced surgical times, a lower PCF formation rate, which involves an early removal of the nasogastric tube, and reduced hospitalization times. Further studies with a larger case series will be necessary to confirm the results obtained and to standardize the surgical technique., Competing Interests: Conflict of interestThe authors declare no conflict of interest, (© Association of Otolaryngologists of India 2023. Springer Nature or its licensor (e.g. a society or other partner) holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law.)
- Published
- 2023
- Full Text
- View/download PDF
44. Locoregional Flaps for the Reconstruction of Midface Skin Defects: A Collection of Key Surgical Techniques.
- Author
-
Salzano G, Maffìa F, Vaira LA, Committeri U, Copelli C, Maglitto F, Manfuso A, Abbate V, Bonavolontà P, Scarpa A, Califano L, and Dell'Aversana Orabona G
- Abstract
Background: The reconstruction of midface skin defects represents a challenge for the head and neck surgeon due to the midface's significant role in defining important facial traits. Due to the high complexity of the midface region, there is no possibility to use one definitive flap for all purposes. For moderate defects, the most common reconstructive techniques are represented by regional flaps. These flaps can be defined as donor tissue with a pedunculated axial blood supply not necessarily adjacent to the defect. The aim of this study is to highlight the more common surgical techniques adopted for midface reconstruction, providing a focus on each technique with its description and indications., Methods: A literature review was conducted using PubMed, an international database. The target of the research was to collect at least 10 different surgical techniques., Results: Twelve different techniques were selected and cataloged. The flaps included were the bilobed flap, rhomboid flap, facial-artery-based flaps (nasolabial flap, island composite nasal flap, retroangular flap), cervicofacial flap, paramedian forehead flap, frontal hairline island flap, keystone flap, Karapandzic flap, Abbè flap, and Mustardè flap., Conclusions: The study of the facial subunits, the location and size of the defect, the choice of the appropriate flap, and respect for the vascular pedicles are the key elements for optimal outcomes.
- Published
- 2023
- Full Text
- View/download PDF
45. SARS-CoV-2 Effects on Psychophysical Olfactory Scores: Prospective Study With Evaluation Before and 60-Days After Infection.
- Author
-
Vaira LA, Lechien JR, Salzano G, Maglitto F, Boscolo-Rizzo P, Hopkins C, and De Riu G
- Subjects
- Humans, Smell, SARS-CoV-2, Prospective Studies, Olfaction Disorders diagnosis, Olfaction Disorders etiology, COVID-19 complications
- Abstract
The aim of this study was to prospectively evaluate the olfactory function in a series of individuals infected with SARS-CoV-2 and who had undergone psychophysical olfactory assessment prior to infection. Individuals unexposed to SARS-CoV-2 infection underwent a psychophysical evaluation of smell with the Sniffin' Sticks test. The subjects were followed prospectively and included in the study if they developed SARS-CoV-2 infection with a second test 60 days after recovery. At the 60-day follow-up of the 41 included subjects, 2 (4.9%) self-reported persistent olfactory dysfunction (OD). The differences between TDI scores before and after infection were statistically significant (37 [interquartile range (IQR), 34.25-39.25] vs 34.75 [IQR, 32.25-38]; p = .021). Analyzing the individual olfactory domains, the differences were significant for threshold (T) (9.75 [IQR, 9-11.25] vs 8.25 [IQR, 7.25-10.25]; p = .009) but not for odor discrimination (D) (p = .443) and identification (I) (p = .159). SARS-CoV-2 causes a significant reduction in the olfactory function, in particular affecting the olfactory threshold, even in subjects who do not self-report an OD., (© 2023 American Academy of Otolaryngology--Head and Neck Surgery Foundation.)
- Published
- 2023
- Full Text
- View/download PDF
46. Prevalence of olfactory dysfunction in D614G, alpha, delta and omicron waves: a psychophysical case-control study.
- Author
-
Vaira LA, Lechien JR, Deiana G, Salzano G, Maglitto F, Piombino P, Mazzatenta A, Boscolo-Rizzo P, Hopkins C, and De Riu G
- Subjects
- Adult, Humans, Case-Control Studies, Pandemics, Prevalence, COVID-19 epidemiology, COVID-19 physiopathology, COVID-19 virology, Olfaction Disorders diagnosis, Olfaction Disorders epidemiology, Olfaction Disorders virology, SARS-CoV-2
- Abstract
Background: The purpose of this study was to compare the prevalence of olfactory dysfunction (OD) at different stages of the COVID-19 pandemic by evaluating subjects diagnosed with SARS-CoV-2 infection during the Omicron wave with psychophysical tests and comparing the results with those obtained from patients infected during the D614G, Alpha and Delta waves and with those of a control group., Methodology: The study included adult patients diagnosed with SARS-CoV-2 infection. Depending on the time of diagnosis, the subjects were divided into four study groups: D614G; Alpha, Delta and Omicron variant groups. A group of uninfected individuals was used as control. All subjects underwent psychophysical evaluation of the olfactory function with the Connecticut Chemosensory Clinical Research Center olfactory test (D614G and Alpha groups) or the extended version of the Sniffin'Sticks test (Delta, Omicron and control groups)., Results: 372 cases (134 D614G group, 118 Alpha group, 32 in Delta group and 88 Omicron group) were recruited and evaluated within 10 days of infection, alongside 80 controls. Patients self-reported olfactory loss in 72.4% of cases in the D614G group, in 75.4% of cases in the Alpha group, in 65.6% of cases in the Delta group and in 18.1% in the Omicron group. Psychophysical evaluation revealed a prevalence of OD: 80.6%, 83.0%, 65.6% and 36.3% in the D614G, Alpha, Delta and Omicron group respectively. The differences between the D614G, Alpha and Delta groups were not statistically significant. The Omicron group demonstrated a significantly lower prevalence of OD than the other variants but still significantly higher than the controls., Conclusions: During the Omicron wave OD was less prevalent than during the D614G, Alpha and Delta periods. One-third of patients have reduced olfactory function on psychophysical evaluation during the Omicron wave. Our results should be considered with caution as the VOC has not been determined with certainty.
- Published
- 2023
- Full Text
- View/download PDF
47. Incidence of Orbital Side Effects in Zygomaticomaxillary Complex and Isolated Orbital Walls Fractures: A Retrospective Study in South Italy and a Brief Review of the Literature.
- Author
-
Committeri U, Arena A, Carraturo E, Austoni M, Germano C, Salzano G, De Riu G, Giovacchini F, Maglitto F, Abbate V, Bonavolontà P, Califano L, and Piombino P
- Abstract
Zygomaticomaxillary complex and isolated orbital walls fractures are one of the most common fractures of the midface, often presenting orbital symptoms and complications. Our study was born with the aim of understanding the trend in the incidence of orbital presurgical symptoms, specifically diplopia, enophthalmos and exophthalmos, in the Campania Region in southern Italy. We conducted a retrospective, monocentric observational study at the Maxillofacial Surgery Unit of the Federico II University Hospital of Naples, enrolling 402 patients who reported a fracture of the zygomaticomaxillary complex and orbital floor region from 15 June 2021 to 15 June 2022. Patients were evaluated by age, gender, etiology, type of fracture, preoperative orbital side effects and symptoms. Pre-surgical side effects were studied, and 16% of patients ( n = 66) developed diplopia. Diplopia was most common in patients previously operated on for orbital wall fractures (100%), and least common in patients who reported trauma after interpersonal violence (15%) and road traffic accidents (11%). Exophthalmos appeared only in 1% (six cases); whereas it did not appear in 99% (396 cases). Enophthalmos was present in 4% (sixteen cases), most commonly in interpersonal violence cases (two cases). The frequency of orbital complications in patients with zygomaticomaxillary complex and isolated orbital walls fractures suggests how diplopia remains the most common pre-surgical orbital side effect.
- Published
- 2023
- Full Text
- View/download PDF
48. Are YouTube Videos a Useful and Reliable Source of Information for Patients with Temporomandibular Joint Disorders?
- Author
-
Vaira LA, Sergnese S, Salzano G, Maglitto F, Arena A, Carraturo E, Abbate V, Committeri U, Vellone V, Biglio A, Lechien JR, and De Riu G
- Abstract
Counseling is considered a first-line conservative therapy with respect to temporomandibular joint disorders (TMJD). Nowadays, 50 to 80% of patients acquire health information from the internet before turning to professionals. The purpose of this study has been to investigate the quality of information about TMJD that patients can obtain from YouTube. A YouTube.com search was conducted using the terms "temporomandibular joint disorder"; "limited movement of the mandible"; and "mandibular joint pain". The videos identified were assessed independently by two panels of three professional and lay reviewers with HONcode, modified DISCERN (MD) and the global quality scale (GQS). A total of 106 videos were included. The professional reviewers reported a mean HONcode score of 4.148 ± 1.314 and a mean MD score of 2.519 ± 1.267, testifying to a modest general quality of the videos. The mean GQS score was 2.987 ± 1.012 for the professional and 3.469 ± 0.891 for the lay reviewers ( p < 0.001). The correlations between the ratings were significant between the reviewers within the same group but not between the two groups. The presence of animations significantly influenced the GQS score expressed by the lay reviewers ( p = 0.011) but not that of the professionals ( p = 0.640). The quality of the information on TMJD on YouTube is generally of poor quality. Healthcare systems and professionals should be prepared to correct misinformation and build trusting relationships with patients which are based on quality counseling. Similarly, academic institutions should produce quality content that leads patients with TMJD toward a correct diagnostic-therapeutic process.
- Published
- 2023
- Full Text
- View/download PDF
49. COVID-19 related persistent olfactory disorders represent an unprecedented challenge.
- Author
-
Vaira LA, De Riu G, Salzano G, Maglitto F, Boscolo-Rizzo P, and Lechien JR
- Subjects
- Humans, Smell, Taste Disorders, COVID-19, Olfaction Disorders etiology
- Abstract
Competing Interests: Declaration of competing interest The authors declare that they have no conflict of interests.
- Published
- 2023
- Full Text
- View/download PDF
50. Titanium Internal Fixator Removal in Maxillofacial Surgery: Is It Necessary? A Systematic Review and Meta-Analysis.
- Author
-
Piombino P, Sani L, Sandu G, Carraturo E, De Riu G, Vaira LA, Maglitto F, and Califano L
- Subjects
- Humans, Retrospective Studies, Bone Plates, Mandible surgery, Device Removal, Fracture Fixation, Internal methods, Titanium, Surgery, Oral
- Abstract
Titanium plates and screws are essential devices in maxillofacial surgery since late 1980s, but despite their wide use there is no consensus in titanium internal fixators removal after bone healing. A systematic literature review and meta-analysis were conducted on seventeen retrospective studies. Effect size and 95% confidence intervals were calculated for plate removal (per plate and per patient) and for removal causes (infection, pain, screws complications, exposition, palpability). Odds ratio, 95% confidence intervals, and χ 2 test were measured for sex, smoking, and implant site. Heterogeneity was evaluated with Cochran and Inconstancy test. Obtained data were used to design Forest and Funnel plots. The aim of the study is to identify and clarify reasons and risk factors for plates and screws removal. Infection is the most frequent reason; the habit of tobacco usage and implant site (mandibula) are the main risk factors. The administration of antibiotic prophylaxis is essential, and patients must quit smoking before and after surgery. In conclusion there is no scientific evidence supporting the removal of internal devices as mandatory step of the postoperative procedure., Competing Interests: The authors report no conflicts of interest., (Copyright © 2022 by Mutaz B. Habal, MD.)
- Published
- 2023
- Full Text
- View/download PDF
Catalog
Discovery Service for Jio Institute Digital Library
For full access to our library's resources, please sign in.