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1,191 results on '"Magni G"'

1. A Benchmarking of QCD Evolution at Approximate $N^3LO$

Author

Cooper-Sarkar, A., Cridge, T., Giuli, F., Harland-Lang, L. A., Hekhorn, F., Huston, J., Magni, G., Moch, S., and Thorne, R. S.

Subjects
High Energy Physics - Phenomenology
Abstract

We present a detailed benchmarking of different treatments of the QCD evolution of unpolarized PDFs at approximate $N^3LO$ ($aN^3LO$) order in the QCD coupling. Namely, the implementations in the public $aN^3LO$ releases of the MSHT and NNPDF global PDF fitters, as well as that of the theoretical FHMRUVV collaboration are compared. This follows the same procedure as in previous benchmarking exercises at lower order, that is by considering the impact of this evolution on a set of simple toy PDFs.

Published
2024

2. Les Houches 2023: Physics at TeV Colliders: Standard Model Working Group Report

Author

Andersen, J., Assi, B., Asteriadis, K., Azzurri, P., Barone, G., Behring, A., Benecke, A., Bhattacharya, S., Bothmann, E., Caletti, S., Chen, X., Chiesa, M., Cooper-Sarkar, A., Cridge, T., Gomez, A. Cueto, Datta, S., Dhani, P. K., Donega, M., Engel, T., Ravasio, S. Ferrario, Forte, S., Francavilla, P., Garzelli, M. V., Ghira, A., Ghosh, A., Giuli, F., Gouskos, L., Gras, P., Gütschow, C., Haddad, Y., Harland-Lang, L., Hekhorn, F., Helenius, I., Hinzmann, A., Höche, S., Holguin, J., Huss, A., Huston, J., Ježo, T., Jones, S., Kiebacher, S., Knobbe, M., Kogler, R., Köneke, K., Kunz, L., LeBlanc, M., Loch, P., Centeno, G. Loeschcke, Löschner, M., Maas, A., Magni, G., Maier, A., Marcoli, M., Marzani, S., McFayden, J., Meinzinger, P., Mikuni, V., Moch, S., Nadolsky, P., Napoletano, D., Pellen, M., Plätzer, S., Poncelet, R., Preuss, C., Qu, H., Rabbertz, K., Reichelt, D., Rescia, A., Roloff, J., Röntsch, R., Cruz, S. Sanchez, Sarkar, T., Scyboz, L., Sforza, F., Siódmok, A., Stagnitto, G., Tarek, A., Thorne, R. S., Valassi, A., Whitehead, J., Winter, J., Delaunay, C., Herrmann, B., and Re, E.

Subjects
High Energy Physics - Phenomenology
Abstract

This report presents a short summary of the activities of the "Standard Model" working group for the "Physics at TeV Colliders" workshop (Les Houches, France, 12-30 June, 2023)., Comment: Proceedings of the Standard Model Working Group of the 2023 Les Houches Workshop, Physics at TeV Colliders, Les Houches 12-30 June 2023. 48 pages

Published
2024

3. LHC EFT WG Report: Experimental Measurements and Observables

Author

Castro, N., Cranmer, K., Gritsan, A. V., Howarth, J., Magni, G., Mimasu, K., Rojo, J., Roskes, J., Vryonidou, E., and You, T.

Subjects
High Energy Physics - Phenomenology, High Energy Physics - Experiment
Abstract

The LHC effective field theory working group gathers members of the LHC experiments and the theory community to provide a framework for the interpretation of LHC data in the context of EFT. In this note we discuss experimental observables and corresponding measurements in analysis of the Higgs, top, and electroweak data at the LHC. We review the relationship between operators and measurements relevant for the interpretation of experimental data in the context of a global SMEFT analysis. One of the goals of ongoing effort is bridging the gap between theory and experimental communities working on EFT, and in particular concerning optimised analyses. This note serves as a guide to experimental measurements and observables leading to EFT fits and establishes good practice, but does not present authoritative guidelines how those measurements should be performed., Comment: LHC EFT Working Group note, 55 pages, 17 figures

Published
2022

4. Snowmass 2021 whitepaper: Proton structure at the precision frontier

Author

Amoroso, S., Apyan, A., Armesto, N., Ball, R. D., Bertone, V., Bissolotti, C., Bluemlein, J., Boughezal, R., Bozzi, G., Britzger, D., Buckley, A., Candido, A., Carrazza, S., Celiberto, F. G., Cerci, S., Chachamis, G., Cooper-Sarkar, A. M., Courtoy, A., Cridge, T., Cruz-Martinez, J. M., Giuli, F., Guzzi, M., Gwenlan, C., Harland-Lang, L. A., Hekhorn, F., Hobbs, T. J., Hoeche, S., Huss, A., Huston, J., Jalilian-Marian, J., Klein, M., Krintiras, G. K., Loizides, C., Lin, H. -W., Magni, G., Malaescu, B., Mistlberger, B., Moch, S., Nadolsky, P. M., Nocera, E. R., Olness, F. I., Petriello, F., Pires, J., Rabbertz, K., Rojo, J., Schnell, G., Schwan, C., Siodmok, A., Soper, D. E., Sutton, M., Thorne, R. S., Ubiali, M., Vita, G., Weber, J. H., Xie, K., Yuan, C. -P., and Zhou, B.

Subjects
High Energy Physics - Phenomenology, High Energy Physics - Experiment
Abstract

An overwhelming number of theoretical predictions for hadron colliders require parton distribution functions (PDFs), which are an important ingredient of theory infrastructure for the next generation of high-energy experiments. This whitepaper summarizes the status and future prospects for determination of high-precision PDFs applicable in a wide range of energies and experiments, in particular in precision tests of the Standard Model and in new physics searches at the high-luminosity Large Hadron Collider and Electron-Ion Collider. We discuss the envisioned advancements in experimental measurements, QCD theory, global analysis methodology, and computing that are necessary to bring unpolarized PDFs in the nucleon to the N2LO and N3LO accuracy in the QCD coupling strength. Special attention is given to the new tasks that emerge in the era of the precision PDF analysis, such as those focusing on the robust control of systematic factors both in experimental measurements and theoretical computations. Various synergies between experimental and theoretical studies of the hadron structure are explored, including opportunities for studying PDFs for nuclear and meson targets, PDFs with electroweak contributions or dependence on the transverse momentum, for incisive comparisons between phenomenological models for the PDFs and computations on discrete lattice, and for cross-fertilization with machine learning/AI approaches. [Submitted to the US Community Study on the Future of Particle Physics (Snowmass 2021).], Comment: 83 pages, 27 figures, contribution to Snowmass 2021; v.3: journal version

Published
2022
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6. REGOMA-OSS: a large, Italian, multicenter, prospective, observational study evaluating the efficacy and safety of regorafenib in patients with recurrent glioblastoma

Author

Caccese, M., Desideri, I., Villani, V., Simonelli, M., Buglione, M., Chiesa, S., Franceschi, E., Gaviani, P., Stasi, I., Caserta, C., Brugnara, S., Lolli, I., Bennicelli, E., Bini, P., Cuccu, A.S., Scoccianti, S., Padovan, M., Gori, S., Bonetti, A., Giordano, P., Pellerino, A., Gregucci, F., Riva, N., Cinieri, S., Internò, V., Santoni, M., Pernice, G., Dealis, C., Stievano, L., Paiar, F., Magni, G., De Salvo, G.L., Zagonel, V., and Lombardi, G.

Published
2024
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7. Thermal convection in the crust of the dwarf planet (1) Ceres

Author

Formisano, M., Federico, C., Castillo-Rogez, J., De Sanctis, M. C., and Magni, G.

Subjects
Astrophysics - Earth and Planetary Astrophysics
Abstract

Ceres is the largest body in the Main Belt, and it is characterized by a large abundance of water ice in its interior. This feature is suggested by its relatively low bulk density (2162 kg m$^{-3}$), while its partial differentiation into a rocky core and icy crust is suggested by several geological and geochemical features: minerals and salts produced by aqueous alteration, icy patches on the surface, lobate morphology interpreted as surface flows. In this work we explore how the composition can influence the characteristics of thermal convection in the crust of Ceres. Our results suggest that the onset of thermal convection is difficult and when it occurs it is short lived and this could imply that Ceres preserved deep liquid until present, as recent suggested by the work of Castillo-Rogez et al.. Moreover, cryovolcanism could be driven by diapirism (chemical convection) rather than thermal convection.

Published
2020
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8. Mechanical Ventilator Milano (MVM): A Novel Mechanical Ventilator Designed for Mass Scale Production in Response to the COVID-19 Pandemic

Author

Galbiati, C., Abba, A., Agnes, P., Amaudruz, P., Arba, M., Ardellier-Desages, F., Badia, C., Batignani, G., Bellani, G., Bianchi, G., Bishop, D., Bocci, V., Bonivento, W., Bottino, B., Bouchard, M., Brice, S., Buccino, G., Bussino, S., Caminata, A., Capra, A., Caravati, M., Carlini, M., Carrozzi, L., Cela, J. M., Celano, B., Charette, C., Coelli, S., Constable, M., Cocco, V., Croci, G., Cudmore, S., Molin, A. Dal, D'Auria, S., D'Avenio, G., DeRuiter, J., De Cecco, S., De Lauretis, L., Del Tutto, M., Devoto, A., Dinon, T., Druszkiewicz, E., Fabbri, A., Ferroni, F., Fiorillo, G., Ford, R., Foti, G., Franco, D., Gabriele, F., Abia, P. Garcia, Giarratana, L. S., Givoletti, J., Givoletti, Mi., Gorini, G., Gramellini, E., Grosso, G., Guescini, F., Guetre, E., Hadden, T., Hall, J., Heavey, A., Hersak, G., Hessey, N., Ianni, An., Ienzi, C., Ippolito, V., Kendziora, C. L., King, M., Kittmer, A., Kochanek, I., Kruecken, R., La Commara, M., Leblond, G., Li, X., Lim, C., Lindner, T., Lombardi, T., Long, T., Lu, P., Lukhanin, G., Magni, G., Maharaj, R., Malosio, M., Mapelli, C., Maqueo, P., Margetak, P., Mari, S. M., Martin, L., Massacret, N., McDonald, A., Minuzzo, D., Mohayai, T. A., Tosatti, L. Molinari, Moretti, C., Muraro, A., Nati, F., Noble, A. J., Norrick, A., Olchanski, K., Palumbo, I., Paoletti, R., Paoli, N., Pearson, C., Pellegrino, C., Pesudo, V., Pocar, A., Pontesilli, M., Pordes, R., Pordes, S., Prini, A., Putignano, O., Raaf, J. L., Razeti, M., Razeto, A., Reed, D., Renshaw, A., Rescigno, M., Retiere, F., Rignanese, L. P., Rode, J., Romualdez, L. J., Santorelli, R., Sablone, D., Scapparone, E., Schaubel, T., Shaw, B., Slutsky, A. S., Smith, B., Smith, N. J. T., Spagnolo, P., Spinella, F., Stenzler, A., Steri, A., Stiaccini, L., Stoughton, C., Stringari, P., Tardocchi, M., Tartaglia, R., Testera, G., Tintori, C., Tonazzo, A., Tseng, J., Viscione, E., Vivaldi, F., Wada, M., Wang, H., Westerdale, S., Yue, S., and Zardoni, A.

Subjects
Physics - Medical Physics
Abstract

Presented here is the design of the Mechanical Ventilator Milano (MVM), a novel mechanical ventilator designed for rapid mass production in response to the COVID-19 pandemic to address the urgent shortage of intensive therapy ventilators in many countries, and the growing difficulty in procuring these devices through normal supply chains across borders. This ventilator is an electro-mechanical equivalent of the old and reliable Manley Ventilator, and is able to operate in both pressure-controlled and pressure-supported ventilation modes. MVM is optimized for the COVID-19 emergency, thanks to the collaboration with medical doctors in the front line. MVM is designed for large-scale production in a short amount of time and at a limited cost, as it relays on off-the-shelf components, readily available worldwide. Operation of the MVM requires only a source of compressed oxygen (or compressed medical air) and electrical power. Initial tests of a prototype device with a breathing simulator are also presented. Further tests and developments are underway. At this stage the MVM is not yet a certified medical device but certification is in progress.

Published
2020
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10. New orphan disease therapies from the proteome of industrial plasma processing waste- a treatment for aceruloplasminemia

Author

Zanardi, A, Nardini, I, Raia, S, Conti, A, Ferrini, B, D'Adamo, P, Gilberti, E, Depalma, G, Belloli, S, Monterisi, C, Coliva, A, Rainone, P, Moresco, R, Mori, F, Zurlo, G, Scali, C, Natali, L, Pancanti, A, Giovacchini, P, Magherini, G, Tovani, G, Salvini, L, Cicaloni, V, Tinti, C, Tinti, L, Lana, D, Magni, G, Giovannini, M, Gringeri, A, Caricasole, A, Alessio, M, Zanardi A., Nardini I., Raia S., Conti A., Ferrini B., D'Adamo P., Gilberti E., DePalma G., Belloli S., Monterisi C., Coliva A., Rainone P., Moresco R. M., Mori F., Zurlo G., Scali C., Natali L., Pancanti A., Giovacchini P., Magherini G., Tovani G., Salvini L., Cicaloni V., Tinti C., Tinti L., Lana D., Magni G., Giovannini M. G., Gringeri A., Caricasole A., Alessio M., Zanardi, A, Nardini, I, Raia, S, Conti, A, Ferrini, B, D'Adamo, P, Gilberti, E, Depalma, G, Belloli, S, Monterisi, C, Coliva, A, Rainone, P, Moresco, R, Mori, F, Zurlo, G, Scali, C, Natali, L, Pancanti, A, Giovacchini, P, Magherini, G, Tovani, G, Salvini, L, Cicaloni, V, Tinti, C, Tinti, L, Lana, D, Magni, G, Giovannini, M, Gringeri, A, Caricasole, A, Alessio, M, Zanardi A., Nardini I., Raia S., Conti A., Ferrini B., D'Adamo P., Gilberti E., DePalma G., Belloli S., Monterisi C., Coliva A., Rainone P., Moresco R. M., Mori F., Zurlo G., Scali C., Natali L., Pancanti A., Giovacchini P., Magherini G., Tovani G., Salvini L., Cicaloni V., Tinti C., Tinti L., Lana D., Magni G., Giovannini M. G., Gringeri A., Caricasole A., and Alessio M.

Abstract

Plasma-derived therapeutic proteins are produced through an industrial fractionation process where proteins are purified from individual intermediates, some of which remain unused and are discarded. Relatively few plasma-derived proteins are exploited clinically, with most of available plasma being directed towards the manufacture of immunoglobulin and albumin. Although the plasma proteome provides opportunities to develop novel protein replacement therapies, particularly for rare diseases, the high cost of plasma together with small patient populations impact negatively on the development of plasma-derived orphan drugs. Enabling therapeutics development from unused plasma fractionation intermediates would therefore constitute a substantial innovation. To this objective, we characterized the proteome of unused plasma fractionation intermediates and prioritized proteins for their potential as new candidate therapies for human disease. We selected ceruloplasmin, a plasma ferroxidase, as a potential therapy for aceruloplasminemia, an adult-onset ultra-rare neurological disease caused by iron accumulation as a result of ceruloplasmin mutations. Intraperitoneally administered ceruloplasmin, purified from an unused plasma fractionation intermediate, was able to prevent neurological, hepatic and hematological phenotypes in ceruloplasmin-deficient mice. These data demonstrate the feasibility of transforming industrial waste plasma fraction into a raw material for manufacturing of new candidate proteins for replacement therapies, optimizing plasma use and reducing waste generation.

Published
2024

11. Egocentric and Allocentric Spatial Memory for Body Parts: A Virtual Reality Study

Author

Serino, S, Di Lernia, D, Magni, G, Manenti, P, de Gaspari, S, Riva, G, Repetto, C, Serino S., Di Lernia D., Magni G., Manenti P., de Gaspari S., Riva G., Repetto C., Serino, S, Di Lernia, D, Magni, G, Manenti, P, de Gaspari, S, Riva, G, Repetto, C, Serino S., Di Lernia D., Magni G., Manenti P., de Gaspari S., Riva G., and Repetto C.

Abstract

Extensive literature elucidated the mechanisms underlying the ability to memorize the positions of objects in space. However, less is known about the impact that objects' features have on spatial memory. The present study aims to investigate differences in egocentric and allocentric object-location memory between hand stimuli depicted in a first-person perspective (1PP) or in a third-person one (3PP). Fifty-two adults encoded spatial positions within a virtual museum environment featuring four square buildings. Each of these buildings featured eight paintings positioned along the walls, with two pictures displayed on each of the four walls. Thirty-two stimuli were employed, which represented pictures of the right hand performing various types of gestures. Half of the stimuli depicted the hand in the 1PP, while the other half depicted the hand in the 3PP. Both free and guided explorations served as encoding conditions. Immediately after that, participants underwent a two-step object-location memory task. Participants were provided with a map of the museum and asked to identify the correct building where the image was located (allocentric memory). Then, they were presented with a schematic representation of the exhibition room divided into four sections and instructed to select the section where they thought the picture was located (egocentric memory). Our findings indicate a memory performance boost associated with egocentric recall, regardless of the perspective of the bodily stimuli. The results are discussed considering the emerging literature on the mnemonic properties of body-related stimuli for spatial memory.

Published
2024

12. A prospective randomized multicenter study on the impact of 18F-Choline PET/CT versus conventional imaging for staging intermediate - to high-risk prostate cancer

Author

Evangelista, L., primary, Zattoni, F., additional, Borsasti, E., additional, Trifro, G., additional, Farsad, M., additional, Trenti, E., additional, Chierichetti, F., additional, Bartolomei, M., additional, Cracco, E., additional, Bombardieri, E., additional, Dal Moro, F., additional, Del Bianco, P., additional, Magni, G., additional, De Salvo, G.L., additional, and Novara, G., additional

Published
2024
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13. A rise in NAD precursor nicotinamide mononucleotide (NMN) after injury promotes axon degeneration

Author

Di Stefano, M, Nascimento-Ferreira, I, Orsomando, G, Mori, V, Gilley, J, Brown, R, Janeckova, L, Vargas, ME, Worrell, LA, Loreto, A, Tickle, J, Patrick, J, Webster, JRM, Marangoni, M, Carpi, FM, Pucciarelli, S, Rossi, F, Meng, W, Sagasti, A, Ribchester, RR, Magni, G, Coleman, MP, and Conforti, L

Subjects
Genetics, Physical Injury - Accidents and Adverse Effects, Neurodegenerative, Neurological, Amidohydrolases, Animals, Axons, Bacterial Proteins, Mice, Nerve Degeneration, Nicotinamide Mononucleotide, Nicotinamide-Nucleotide Adenylyltransferase, Peripheral Nerve Injuries, Biological Sciences, Medical and Health Sciences, Biochemistry & Molecular Biology
Abstract

NAD metabolism regulates diverse biological processes, including ageing, circadian rhythm and axon survival. Axons depend on the activity of the central enzyme in NAD biosynthesis, nicotinamide mononucleotide adenylyltransferase 2 (NMNAT2), for their maintenance and degenerate rapidly when this activity is lost. However, whether axon survival is regulated by the supply of NAD or by another action of this enzyme remains unclear. Here we show that the nucleotide precursor of NAD, nicotinamide mononucleotide (NMN), accumulates after nerve injury and promotes axon degeneration. Inhibitors of NMN-synthesising enzyme NAMPT confer robust morphological and functional protection of injured axons and synapses despite lowering NAD. Exogenous NMN abolishes this protection, suggesting that NMN accumulation within axons after NMNAT2 degradation could promote degeneration. Ectopic expression of NMN deamidase, a bacterial NMN-scavenging enzyme, prolongs survival of injured axons, providing genetic evidence to support such a mechanism. NMN rises prior to degeneration and both the NAMPT inhibitor FK866 and the axon protective protein Wld(S) prevent this rise. These data indicate that the mechanism by which NMNAT and the related Wld(S) protein promote axon survival is by limiting NMN accumulation. They indicate a novel physiological function for NMN in mammals and reveal an unexpected link between new strategies for cancer chemotherapy and the treatment of axonopathies.

Published
2015

14. Saturn satellites as seen by Cassini Mission

Author

Coradini, A., Capaccioni, F., Cerroni, P., Filacchione, G., Magni, G., Orosei, R., Tosi, F., and Turrini, D.

Subjects
Astrophysics - Earth and Planetary Astrophysics
Abstract

In this paper we will summarize some of the most important results of the Cassini mission concerning the satellites of Saturn. Given the long duration of the mission, the complexity of the payload onboard the Cassini Orbiter and the amount of data gathered on the satellites of Saturn, it would be impossible to describe all the new discoveries made, therefore we will describe only some selected, paramount examples showing how Cassini's data confirmed and extended ground-based observations. In particular we will describe the achievements obtained for the satellites Phoebe, Enceladus and Titan. We will also put these examples in the perspective of the overall evolution of the system, stressing out why the selected satellites are representative of the overall evolution of the Saturn system., Comment: 34 pages, 10 figures, to appear on the special issue of Earth, Moon and Planets for the Elba workshop

Published
2009
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15. Probing the history of Solar System through the cratering records on Vesta and Ceres

Author

Turrini, D., Magni, G., and Coradini, A.

Subjects
Astrophysics - Earth and Planetary Astrophysics, Physics - Space Physics
Abstract

Through its connection with HED meteorites, Vesta is known as one of the first bodies to have accreted and differentiated in the Solar Nebula, predating the formation of Jupiter and surviving the violent evolution of the early Solar System. The formation time of Ceres instead is unknown, but it should not postdate that of Jupiter by far. In this work we modelled the collisional histories of Vesta and Ceres at the time of the formation of Jupiter, assumed to be the first giant planet to form. In this first investigation of the evolution of the early Solar System, we did not include the presence of planetary embryos in the disk of planetesimals but we concentrated on the role of the forming Jupiter and the effects of its possible inward migration due to disk-planet interactions. Our results clearly indicate that the formation of the giant planet caused an intense early bombardment in the orbital region of the Main Asteroid Belt. According to our results, Vesta and Ceres would not have survived the Jovian early bombardment if the disk was populated mainly by large planetesimals like those predicted to form in turbulent circumstellar disks. Disks dominated by small bodies, like those predicted to form in quiescent circumstellar disks, or with a varying fraction of the mass in the form of larger (D \geq 100 km) planetesimals represent more favourable environments for the survival of the two asteroids. In those scenarios where they survive, both asteroids had their surfaces saturated by craters as big as 150 km and a few as big as 200 - 300 km. In the case of Vesta, the Jovian early bombardment would have significantly eroded (locally or globally) the crust and possibly caused effusive phenomena similar to the lunar maria, whose crystallisation time would then be directly linked to the time of the formation of Jupiter., Comment: 34 pages, 26 figures and 6 tables, accepted for publication on the Monthly Notices of the Royal Astronomical Society (accepted 2011 January 10; received 2010 November 23; in original form 2010 August 6). Major revisions respect to previous version (extended set of initial conditions, extended analysis and discussion of the results and their implications)

Published
2009
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17. Localized aliphatic organic material on the surface of Ceres

Author

De Sanctis, M. C., Ammannito, E., McSween, H. Y., Raponi, A., Marchi, S., Capaccioni, F., Capria, M. T., Carrozzo, F. G., Ciarniello, M., Fonte, S., Formisano, M., Frigeri, A., Giardino, M., Longobardo, A., Magni, G., McFadden, L. A., Palomba, E., Pieters, C. M., Tosi, F., Zambon, F., Raymond, C. A., and Russell, C. T.

Published
2017

19. Seasonal exposure of carbon dioxide ice on the nucleus of comet 67P/Churyumov-Gerasimenko

Author

Filacchione, G., Raponi, A., Capaccioni, F., Ciarniello, M., Tosi, F., Capria, M. T., De Sanctis, M. C., Migliorini, A., Piccioni, G., Cerroni, P., Barucci, M. A., Fornasier, S., Schmitt, B., Quirico, E., Erard, S., Bockelee-Morvan, D., Leyrat, C., Arnold, G., Mennella, V., Ammannito, E., Bellucci, G., Benkhoff, J., Bibring, J. P., Blanco, A., Blecka, M. I., Carlson, R., Carsenty, U., Colangeli, L., Combes, M., Combi, M., Crovisier, J., Drossart, P., Encrenaz, T., Federico, C., Fink, U., Fonti, S., Fulchignoni, M., Ip, W.-H., Irwin, P., Jaumann, R., Kuehrt, E., Langevin, Y., Magni, G., McCord, T., Moroz, L., Mottola, S., Palomba, E., Schade, U., Stephan, K., Taylor, F., Tiphene, D., Tozzi, G. P., Beck, P., Biver, N., Bonal, L., Combe, J.-Ph., Despan, D., Flamini, E., Formisano, M., Frigeri, A., Grassi, D., Gudipati, M. S., Kappel, D., Longobardo, A., Mancarella, F., Markus, K., Merlin, F., Orosei, R., Rinaldi, G., Cartacci, M., Cicchetti, A., Hello, Y., Henry, F., Jacquinod, S., Reess, J. M., Noschese, R., Politi, R., and Peter, G.

Published
2016

20. How to avoid rapid carbon dioxide changes at the start of veno-venous extracorporeal membrane oxygenation: Role of end-tidal CO2 monitoring

Author

Giani, M, Lucchini, A, Magni, G, Villa, S, Rona, R, Fumagalli, R, Foti, G, Giani, Marco, Lucchini, Alberto, Magni, Gloria, Villa, Silvia, Rona, Roberto, Fumagalli, Roberto, Foti, Giuseppe, Giani, M, Lucchini, A, Magni, G, Villa, S, Rona, R, Fumagalli, R, Foti, G, Giani, Marco, Lucchini, Alberto, Magni, Gloria, Villa, Silvia, Rona, Roberto, Fumagalli, Roberto, and Foti, Giuseppe

Abstract

Background: Venovenous ECMO is a lifesaving technique for patients with severe respiratory failure. Management of carbon dioxide (CO2) levels at ECMO start is crucial, as recent studies found an association between rapid CO2 shifts and increased incidence of neurological complications. Purpose: To describe the role of end tidal CO2 (etCO2) monitoring at the ECMO start to minimize carbon dioxide shifts. Research design: Retrospective cohort study. Methods: We performed a retrospective analysis of patients who started venovenous ECMO support at our institution between 2011 and 2021. We analysed the minute-by-minute variations of etCO2, ventilatory parameters and arterial blood gas before and after the ECMO start. Results: 36 patients with a complete dataset of parameters were included. After the ECMO start, minute ventilation was progressively reduced from 10.8±;3.3 to 2.9±1.2 L/min (p<0.001). etCO2 did not vary significantly (baseline 37±10 vs 35±9 mmHg 20 minutes after ECMO start, p = 0.36). Despite a stable etCO2 level, a mild drop of arterial CO2 tension (9.5 mmHg, corresponding to a 18% change) was recorded at the first ABG sampled after the ECMO start. No patient developed neurological complications after the ECMO commencement. Conclusion: etCO2 monitoring during ECMO start is feasible and allows to adjust gas flow and ventilator settings to limit changes in arterial CO2 levels.

Published
2023

21. Distribution of phyllosilicates on the surface of Ceres

Author

Ammannito, E., DeSanctis, M. C., Ciarniello, M., Frigeri, A., Carrozzo, F. G., Combe, J.-Ph., Ehlmann, B. L., Marchi, S., McSween, H. Y., Raponi, A., Toplis, M. J., Tosi, F., Castillo-Rogez, J. C., Capoccioni, F., Capria, M. T., Fonte, S., Giardino, M., Jaumann, R., Longobardo, A., Joy, S. P., Magni, G., McCord, T. B., McFadden, L. A., Palomba, E., Pieters, C. M., Polanskey, C. A., Rayman, M. D., Raymond, C. A., Schenk, P. M., Zambon, F., and Russell, C. T.

Published
2016

25. The organic-rich surface of comet 67P/Churyumov-Gerasimenko as seen by VIRTIS/Rosetta

Author

Capaccioni, F., Coradini, A., Filacchione, G., Erard, S., Arnold, G., Drossart, P., De Sanctis, M. C., Bockelee-Morvan, D., Capria, M. T., Tosi, F., Leyrat, C., Schmitt, B., Quirico, E., Cerroni, P., Mennella, V., Raponi, A., Ciarniello, M., MeCord, T., Moroz, L., Palomba, E., Ammannito, E., Barucci, M. A., Bellucci, G., Benkhoff, J., Bibring, J. P., Blanco, A., Blecka, M., Carlson, R., Carsenty, U., Colangeli, L., Combes, M., Combi, M., Crovisier, J., Encrenaz, T., Federico, C., Fink, U., Fonti, S., Ip, W. H., Irwin, P., Jaumann, R., Kuehrt, E., Langevin, Y., Magni, G., Mottola, S., Orofino, V., Palumbo, P., Piccioni, G., Schade, U., Taylor, F., Tiphene, D., Tozzi, G. P., Beck, P., Biver, N., Bonal, L., Combe, J.-Ph., Despan, D., Flamini, E., Fornasier, S., Frigeri, A., Grassi, D., Gudipati, M., Longobardo, A., Markus, K., Merlin, F., Orosei, R., Rinaldi, G., Stephan, K., Cartacci, M., Cicchetti, A., Giuppi, S., Hello, Y., Henry, F., Jacquinod, S., Noschese, R., Peter, G., Politi, R., Reess, J. M., and Semery, A.

Published
2015

27. The VIR Spectrometer

Author

VIR Team, De Sanctis, M. C., Coradini, A., Ammannito, E., Filacchione, G., Capria, M. T., Fonte, S., Magni, G., Barbis, A., Bini, A., Dami, M., Ficai-Veltroni, I., Preti, G., Russell, Christopher, editor, and Raymond, Carol, editor

Published
2012
Full Text
View/download PDF

29. The novel Mechanical Ventilator Milano for the COVID-19 pandemic

Author

Abba, A, Accorsi, C, Agnes, P, Alessi, E, Amaudruz, P, Annovi, A, Desages, F, Back, S, Badia, C, Bagger, J, Basile, V, Batignani, G, Bayo, A, Bell, B, Beschi, M, Biagini, D, Bianchi, G, Bicelli, S, Bishop, D, Boccali, T, Bombarda, A, Bonfanti, S, Bonivento, W, Bouchard, M, Breviario, M, Brice, S, Brown, R, Calvo-Mozota, J, Camozzi, L, Camozzi, M, Capra, A, Caravati, M, Carlini, M, Ceccanti, A, Celano, B, Cela Ruiz, J, Charette, C, Cogliati, G, Constable, M, Crippa, C, Croci, G, Cudmore, S, Dahl, C, Dal Molin, A, Daley, M, Di Guardo, C, D'Avenio, G, Davignon, O, Del Tutto, M, De Ruiter, J, Devoto, A, Diaz Gomez Maqueo, P, Di Francesco, F, Dossi, M, Druszkiewicz, E, Duma, C, Elliott, E, Farina, D, Fernandes, C, Ferroni, F, Finocchiaro, G, Fiorillo, G, Ford, R, Foti, G, Fournier, R, Franco, D, Fricbergs, C, Gabriele, F, Galbiati, C, Garcia Abia, P, Gargantini, A, Giacomelli, L, Giacomini, F, Giarratana, L, Gillespie, S, Giorgi, D, Girma, T, Gobui, R, Goeldi, D, Golf, F, Gorel, P, Gorini, G, Gramellini, E, Grosso, G, Guescini, F, Guetre, E, Hackman, G, Hadden, T, Hawkins, W, Hayashi, K, Heavey, A, Hersak, G, Hessey, N, Hockin, G, Hudson, K, Ianni, A, Ienzi, C, Ippolito, V, James, C, Jillings, C, Kendziora, C, Khan, S, Kim, E, King, M, King, S, Kittmer, A, Kochanek, I, Kowalkowski, J, Krucken, R, Kushoro, M, Kuula, S, Laclaustra, M, Leblond, G, Lee, L, Lennarz, A, Leyton, M, Li, X, Liimatainen, P, Lim, C, Lindner, T, Lomonaco, T, Lu, P, Lubna, R, Lukhanin, G, Luzon, G, Macdonald, M, Magni, G, Maharaj, R, Manni, S, Mapelli, C, Margetak, P, Martin, L, Martin, S, Martinez, M, Massacret, N, Mcclurg, P, Mcdonald, A, Meazzi, E, Migalla, R, Mohayai, T, Tosatti, L, Monzani, G, Moretti, C, Morrison, B, Mountaniol, M, Muraro, A, Napoli, P, Nati, F, Natzke, C, Noble, A, Norrick, A, Olchanski, K, Ortiz De Solorzano, A, Padula, F, Pallavicini, M, Palumbo, I, Panontin, E, Papini, N, Parmeggiano, L, Parmeggiano, S, Patel, K, Patel, A, Paterno, M, Pellegrino, C, Pelliccione, P, Pesudo, V, Pocar, A, Pope, A, Pordes, S, Prelz, F, Putignano, O, Raaf, J, Ratti, C, Razeti, M, Razeto, A, Reed, D, Refsgaard, J, Reilly, T, Renshaw, A, Retriere, F, Riccobene, E, Rigamonti, D, Rizzi, A, Rode, J, Romualdez, J, Russel, L, Sablone, D, Sala, S, Salomoni, D, Salvo, P, Sandoval, A, Sansoucy, E, Santorelli, R, Savarese, C, Scapparone, E, Schaubel, T, Scorza, S, Settimo, M, Shaw, B, Shawyer, S, Sher, A, Shi, A, Skensved, P, Slutsky, A, Smith, B, Smith, N, Stenzler, A, Straubel, C, Stringari, P, Suchenek, M, Sur, B, Tacchino, S, Takeuchi, L, Tardocchi, M, Tartaglia, R, Thomas, E, Trask, D, Tseng, J, Tseng, L, Vanpagee, L, Vedia, V, Velghe, B, Viel, S, Visioli, A, Viviani, L, Vonica, D, Wada, M, Walter, D, Wang, H, Wang, M, Westerdale, S, Wood, D, Yates, D, Yue, S, Zambrano, V, Abba A., Accorsi C., Agnes P., Alessi E., Amaudruz P., Annovi A., Desages F. A., Back S., Badia C., Bagger J., Basile V., Batignani G., Bayo A., Bell B., Beschi M., Biagini D., Bianchi G., Bicelli S., Bishop D., Boccali T., Bombarda A., Bonfanti S., Bonivento W. M., Bouchard M., Breviario M., Brice S., Brown R., Calvo-Mozota J. M., Camozzi L., Camozzi M., Capra A., Caravati M., Carlini M., Ceccanti A., Celano B., Cela Ruiz J. M., Charette C., Cogliati G., Constable M., Crippa C., Croci G., Cudmore S., Dahl C. E., Dal Molin A., Daley M., Di Guardo C., D'Avenio G., Davignon O., Del Tutto M., De Ruiter J., Devoto A., Diaz Gomez Maqueo P., Di Francesco F., Dossi M., Druszkiewicz E., Duma C., Elliott E., Farina D., Fernandes C., Ferroni F., Finocchiaro G., Fiorillo G., Ford R., Foti G., Fournier R. D., Franco D., Fricbergs C., Gabriele F., Galbiati C., Garcia Abia P., Gargantini A., Giacomelli L., Giacomini F., Giarratana L. S., Gillespie S., Giorgi D., Girma T., Gobui R., Goeldi D., Golf F., Gorel P., Gorini G., Gramellini E., Grosso G., Guescini F., Guetre E., Hackman G., Hadden T., Hawkins W., Hayashi K., Heavey A., Hersak G., Hessey N., Hockin G., Hudson K., Ianni A., Ienzi C., Ippolito V., James C. C., Jillings C., Kendziora C., Khan S., Kim E., King M., King S., Kittmer A., Kochanek I., Kowalkowski J., Krucken R., Kushoro M., Kuula S., Laclaustra M., Leblond G., Lee L., Lennarz A., Leyton M., Li X., Liimatainen P., Lim C., Lindner T., Lomonaco T., Lu P., Lubna R., Lukhanin G. A., Luzon G., Macdonald M., Magni G., Maharaj R., Manni S., Mapelli C., Margetak P., Martin L., Martin S., Martinez M., Massacret N., McClurg P., McDonald A. B., Meazzi E., Migalla R., Mohayai T., Tosatti L. M., Monzani G., Moretti C., Morrison B., Mountaniol M., Muraro A., Napoli P., Nati F., Natzke C. R., Noble A. J., Norrick A., Olchanski K., Ortiz De Solorzano A., Padula F., Pallavicini M., Palumbo I., Panontin E., Papini N., Parmeggiano L., Parmeggiano S., Patel K., Patel A., Paterno M., Pellegrino C., Pelliccione P., Pesudo V., Pocar A., Pope A., Pordes S., Prelz F., Putignano O., Raaf J. L., Ratti C., Razeti M., Razeto A., Reed D., Refsgaard J., Reilly T., Renshaw A., Retriere F., Riccobene E., Rigamonti D., Rizzi A., Rode J., Romualdez J., Russel L., Sablone D., Sala S., Salomoni D., Salvo P., Sandoval A., Sansoucy E., Santorelli R., Savarese C., Scapparone E., Schaubel T., Scorza S., Settimo M., Shaw B., Shawyer S., Sher A., Shi A., Skensved P., Slutsky A., Smith B., Smith N. J. T., Stenzler A., Straubel C., Stringari P., Suchenek M., Sur B., Tacchino S., Takeuchi L., Tardocchi M., Tartaglia R., Thomas E., Trask D., Tseng J., Tseng L., Vanpagee L., Vedia V., Velghe B., Viel S., Visioli A., Viviani L., Vonica D., Wada M., Walter D., Wang H., Wang M. H. L. S., Westerdale S., Wood D., Yates D., Yue S., Zambrano V., Abba, A, Accorsi, C, Agnes, P, Alessi, E, Amaudruz, P, Annovi, A, Desages, F, Back, S, Badia, C, Bagger, J, Basile, V, Batignani, G, Bayo, A, Bell, B, Beschi, M, Biagini, D, Bianchi, G, Bicelli, S, Bishop, D, Boccali, T, Bombarda, A, Bonfanti, S, Bonivento, W, Bouchard, M, Breviario, M, Brice, S, Brown, R, Calvo-Mozota, J, Camozzi, L, Camozzi, M, Capra, A, Caravati, M, Carlini, M, Ceccanti, A, Celano, B, Cela Ruiz, J, Charette, C, Cogliati, G, Constable, M, Crippa, C, Croci, G, Cudmore, S, Dahl, C, Dal Molin, A, Daley, M, Di Guardo, C, D'Avenio, G, Davignon, O, Del Tutto, M, De Ruiter, J, Devoto, A, Diaz Gomez Maqueo, P, Di Francesco, F, Dossi, M, Druszkiewicz, E, Duma, C, Elliott, E, Farina, D, Fernandes, C, Ferroni, F, Finocchiaro, G, Fiorillo, G, Ford, R, Foti, G, Fournier, R, Franco, D, Fricbergs, C, Gabriele, F, Galbiati, C, Garcia Abia, P, Gargantini, A, Giacomelli, L, Giacomini, F, Giarratana, L, Gillespie, S, Giorgi, D, Girma, T, Gobui, R, Goeldi, D, Golf, F, Gorel, P, Gorini, G, Gramellini, E, Grosso, G, Guescini, F, Guetre, E, Hackman, G, Hadden, T, Hawkins, W, Hayashi, K, Heavey, A, Hersak, G, Hessey, N, Hockin, G, Hudson, K, Ianni, A, Ienzi, C, Ippolito, V, James, C, Jillings, C, Kendziora, C, Khan, S, Kim, E, King, M, King, S, Kittmer, A, Kochanek, I, Kowalkowski, J, Krucken, R, Kushoro, M, Kuula, S, Laclaustra, M, Leblond, G, Lee, L, Lennarz, A, Leyton, M, Li, X, Liimatainen, P, Lim, C, Lindner, T, Lomonaco, T, Lu, P, Lubna, R, Lukhanin, G, Luzon, G, Macdonald, M, Magni, G, Maharaj, R, Manni, S, Mapelli, C, Margetak, P, Martin, L, Martin, S, Martinez, M, Massacret, N, Mcclurg, P, Mcdonald, A, Meazzi, E, Migalla, R, Mohayai, T, Tosatti, L, Monzani, G, Moretti, C, Morrison, B, Mountaniol, M, Muraro, A, Napoli, P, Nati, F, Natzke, C, Noble, A, Norrick, A, Olchanski, K, Ortiz De Solorzano, A, Padula, F, Pallavicini, M, Palumbo, I, Panontin, E, Papini, N, Parmeggiano, L, Parmeggiano, S, Patel, K, Patel, A, Paterno, M, Pellegrino, C, Pelliccione, P, Pesudo, V, Pocar, A, Pope, A, Pordes, S, Prelz, F, Putignano, O, Raaf, J, Ratti, C, Razeti, M, Razeto, A, Reed, D, Refsgaard, J, Reilly, T, Renshaw, A, Retriere, F, Riccobene, E, Rigamonti, D, Rizzi, A, Rode, J, Romualdez, J, Russel, L, Sablone, D, Sala, S, Salomoni, D, Salvo, P, Sandoval, A, Sansoucy, E, Santorelli, R, Savarese, C, Scapparone, E, Schaubel, T, Scorza, S, Settimo, M, Shaw, B, Shawyer, S, Sher, A, Shi, A, Skensved, P, Slutsky, A, Smith, B, Smith, N, Stenzler, A, Straubel, C, Stringari, P, Suchenek, M, Sur, B, Tacchino, S, Takeuchi, L, Tardocchi, M, Tartaglia, R, Thomas, E, Trask, D, Tseng, J, Tseng, L, Vanpagee, L, Vedia, V, Velghe, B, Viel, S, Visioli, A, Viviani, L, Vonica, D, Wada, M, Walter, D, Wang, H, Wang, M, Westerdale, S, Wood, D, Yates, D, Yue, S, Zambrano, V, Abba A., Accorsi C., Agnes P., Alessi E., Amaudruz P., Annovi A., Desages F. A., Back S., Badia C., Bagger J., Basile V., Batignani G., Bayo A., Bell B., Beschi M., Biagini D., Bianchi G., Bicelli S., Bishop D., Boccali T., Bombarda A., Bonfanti S., Bonivento W. M., Bouchard M., Breviario M., Brice S., Brown R., Calvo-Mozota J. M., Camozzi L., Camozzi M., Capra A., Caravati M., Carlini M., Ceccanti A., Celano B., Cela Ruiz J. M., Charette C., Cogliati G., Constable M., Crippa C., Croci G., Cudmore S., Dahl C. E., Dal Molin A., Daley M., Di Guardo C., D'Avenio G., Davignon O., Del Tutto M., De Ruiter J., Devoto A., Diaz Gomez Maqueo P., Di Francesco F., Dossi M., Druszkiewicz E., Duma C., Elliott E., Farina D., Fernandes C., Ferroni F., Finocchiaro G., Fiorillo G., Ford R., Foti G., Fournier R. D., Franco D., Fricbergs C., Gabriele F., Galbiati C., Garcia Abia P., Gargantini A., Giacomelli L., Giacomini F., Giarratana L. S., Gillespie S., Giorgi D., Girma T., Gobui R., Goeldi D., Golf F., Gorel P., Gorini G., Gramellini E., Grosso G., Guescini F., Guetre E., Hackman G., Hadden T., Hawkins W., Hayashi K., Heavey A., Hersak G., Hessey N., Hockin G., Hudson K., Ianni A., Ienzi C., Ippolito V., James C. C., Jillings C., Kendziora C., Khan S., Kim E., King M., King S., Kittmer A., Kochanek I., Kowalkowski J., Krucken R., Kushoro M., Kuula S., Laclaustra M., Leblond G., Lee L., Lennarz A., Leyton M., Li X., Liimatainen P., Lim C., Lindner T., Lomonaco T., Lu P., Lubna R., Lukhanin G. A., Luzon G., Macdonald M., Magni G., Maharaj R., Manni S., Mapelli C., Margetak P., Martin L., Martin S., Martinez M., Massacret N., McClurg P., McDonald A. B., Meazzi E., Migalla R., Mohayai T., Tosatti L. M., Monzani G., Moretti C., Morrison B., Mountaniol M., Muraro A., Napoli P., Nati F., Natzke C. R., Noble A. J., Norrick A., Olchanski K., Ortiz De Solorzano A., Padula F., Pallavicini M., Palumbo I., Panontin E., Papini N., Parmeggiano L., Parmeggiano S., Patel K., Patel A., Paterno M., Pellegrino C., Pelliccione P., Pesudo V., Pocar A., Pope A., Pordes S., Prelz F., Putignano O., Raaf J. L., Ratti C., Razeti M., Razeto A., Reed D., Refsgaard J., Reilly T., Renshaw A., Retriere F., Riccobene E., Rigamonti D., Rizzi A., Rode J., Romualdez J., Russel L., Sablone D., Sala S., Salomoni D., Salvo P., Sandoval A., Sansoucy E., Santorelli R., Savarese C., Scapparone E., Schaubel T., Scorza S., Settimo M., Shaw B., Shawyer S., Sher A., Shi A., Skensved P., Slutsky A., Smith B., Smith N. J. T., Stenzler A., Straubel C., Stringari P., Suchenek M., Sur B., Tacchino S., Takeuchi L., Tardocchi M., Tartaglia R., Thomas E., Trask D., Tseng J., Tseng L., Vanpagee L., Vedia V., Velghe B., Viel S., Visioli A., Viviani L., Vonica D., Wada M., Walter D., Wang H., Wang M. H. L. S., Westerdale S., Wood D., Yates D., Yue S., and Zambrano V.

Abstract

This paper presents the Mechanical Ventilator Milano (MVM), a novel intensive therapy mechanical ventilator designed for rapid, large-scale, low-cost production for the COVID-19 pandemic. Free of moving mechanical parts and requiring only a source of compressed oxygen and medical air to operate, the MVM is designed to support the long-term invasive ventilation often required for COVID-19 patients and operates in pressure-regulated ventilation modes, which minimize the risk of furthering lung trauma. The MVM was extensively tested against ISO standards in the laboratory using a breathing simulator, with good agreement between input and measured breathing parameters and performing correctly in response to fault conditions and stability tests. The MVM has obtained Emergency Use Authorization by U.S. Food and Drug Administration (FDA) for use in healthcare settings during the COVID-19 pandemic and Health Canada Medical Device Authorization for Importation or Sale, under Interim Order for Use in Relation to COVID-19. Following these certifications, mass production is ongoing and distribution is under way in several countries. The MVM was designed, tested, prepared for certification, and mass produced in the space of a few months by a unique collaboration of respiratory healthcare professionals and experimental physicists, working with industrial partners, and is an excellent ventilator candidate for this pandemic anywhere in the world.

Published
2021

30. Bright carbonate deposits as evidence of aqueous alteration on (1) Ceres

Author

De Sanctis, M.C., Raponi, A., Ammannito, E., Ciarniello, M., Toplis, M.J., McSween, H.Y., Castillo-Rogez, J.C., Ehlmann, B.L., Carrozzo, F.G., Marchi, S., Tosi, F., Zambon, F., Capaccioni, F., Capria, M.T., Fonte, S., Formisano, M., Frigeri, A., Giardino, M., Longobardo, A., Magni, G., Palomba, E., McFadden, L.A., Pieters, C.M., Jaumann, R., Schenk, P., Mugnuolo, R., Raymond, C.A., and Russell, C.T.

Subjects
Carbonates -- Properties -- Analysis, Ceres (Asteroid) -- Observations -- Research -- Analysis, Environmental issues, Science and technology, Zoology and wildlife conservation
Abstract

The typically dark surface of the dwarf planet Ceres is punctuated by areas of much higher albedo, most prominently in the Occator crater (1). These small bright areas have been tentatively interpreted as containing a large amount of hydrated magnesium sulfate (1), in contrast to the average surface, which is a mixture of low-albedo materials and magnesium phyllosilicates, ammoniated phyllosilicates and carbonates (2-4). Here we report high spatial and spectral resolution near-infrared observations of the bright areas in the Occator crater on Ceres. Spectra of these bright areas are consistent with a large amount of sodium carbonate, constituting the most concentrated known extraterrestrial occurrence of carbonate on kilometre-wide scales in the Solar System. The carbonates are mixed with a dark component and small amounts of phyllosilicates, as well as ammonium carbonate or ammonium chloride. Some of these compounds have also been detected in the plume of Saturn's sixth-largest moon Enceladus (5). The compounds are endogenous and we propose that they are the solid residue of crystallization of brines and entrained altered solids that reached the surface from below. The heat source may have been transient (triggered by impact heating). Alternatively, internal temperatures may be above the eutectic temperature of subsurface brines, in which case fluids may exist at depth on Ceres today., Occator is a prominent, geologically young crater (1,6) (diameter ~90 km, 19.4° N, 239.0° E), and its brightest region (Fig. 1) is at the centre of the crater, close to [...]

Published
2016

31. Ammoniated phyllosilicates with a likely outer Solar System origin on (1) Ceres

Author

De Sanctis, M.C., Ammannito, E., Raponi, A., Marchi, S., Mccord, T.B., McSween, H.Y., Capaccioni, F., Capria, M.T., Carrozzo, F.G., Ciarniello, M., Longobardo, A., Tosi, F., Fonte, S., Formisano, M., Frigeri, A., Giardino, M., Magni, G., Palomba, E., Turrini, D., Zambon, F., Combe, J.-P., Feldman, W., Jaumann, R., McFadden, L.A., Pieters, C.M., Prettyman, T., Toplis, M., Raymond, C.A., and Russell, C.T.

Subjects
Phyllosilicates -- Observations, Ceres (Asteroid) -- Observations, Environmental issues, Science and technology, Zoology and wildlife conservation, Observations
Abstract

Studies of the dwarf planet (1) Ceres using ground-based and orbiting telescopes have concluded that its closest meteoritic analogues are the volatile-rich CI and CM carbonaceous chondrites (1, 2). Water in clay minerals (3), ammoniated phyllosilicates (4), or a mixture of Mg[(OH).sub.2] (brucite), [Mg.sub.2]C[O.sub.3] and iron-rich serpentine (5, 6) have all been proposed to exist on the surface. In particular, brucite has been suggested from analysis of the mid-infrared spectrum of Ceres (6). But the lack of spectral data across telluric absorption bands in the wavelength region 2.5 to 2.9 micrometres--where the OH stretching vibration and the [H.sub.2]O bending overtone are found--has precluded definitive identifications. In addition, water vapour around Ceres has recently been reported (7), possibly originating from localized sources. Here we report spectra of Ceres from 0.4 to 5 micrometres acquired at distances from ~82,000 to 4,300 kilometres from the surface. Our measurements indicate widespread ammoniated phyllosilicates across the surface, but no detectable water ice. Ammonia, accreted either as organic matter or as ice, may have reacted with phyllosilicates on Ceres during differentiation. This suggests that material from the outer Solar System was incorporated into Ceres, either during its formation at great heliocentric distance or by incorporation of material transported into the main asteroid belt., The Visible-Infrared Mapping Spectrometer VIR (8) on the Dawn spacecraft (9) obtained multi-spectral images of Ceres' surface in the spectral range 0.4-5 µm with an instantaneous field of view of [...]

Published
2015

33. SMEFT analysis of the electroweak sector: challenges beyond dimension 6

Author

Magni, G, Gomez-Ambrosio, R, Magni, Giacomo, Gomez-Ambrosio, Raquel, Magni, G, Gomez-Ambrosio, R, Magni, Giacomo, and Gomez-Ambrosio, Raquel

Abstract

In these proceedings we present the latest developments in our effort to include vector boson scattering (VBS) measurements into global SMEFT fits of LHC data. We present some updates to our initial study of arXiv:2101.03180 as well as comment on a possible road map for the inclusion of higher orders beyond dimension 6 in the SMEFT and on the interpretation of VBS data in other EFT frameworks.

Published
2022

34. A Regime switching Student-t copula model for the analysis of cryptocurrencies data

Author

Marco Corazza, Cira Perna, Claudio Pizzi, Marilena Sibillo, Magni, G, Bimonte, G, Naimoli, A, Cortese, F, Bartolucci, F, Pennoni, F, Cortese, F., Bartolucci, F., Pennoni, F., Marco Corazza, Cira Perna, Claudio Pizzi, Marilena Sibillo, Magni, G, Bimonte, G, Naimoli, A, Cortese, F, Bartolucci, F, Pennoni, F, Cortese, F., Bartolucci, F., and Pennoni, F.

Abstract

Flexible statistical models have an important role in explaining the joint distribution of financial returns. In these analyses, it is necessary to consider abrupt switches in the market conditions, especially if the focus is on cryptoassets, the market of which is characterized by high instabilities. Regime switching (RS) copula models represent a powerful tool to formulate the joint distribution of time-series accurately: they are based on a copula distribution with parameters governed by a hidden Markov process of first-order so as to account for the correlation patterns between series. The hidden states represent different market regimes, each described by a state-specific vector of copula parameters. We propose RS copula models as a valuable instrument for describing the joint behavior of log- returns. We choose a Student-t copula function to consider extreme dependent values appropriately as they are often observed in financial returns. We split the modeling process into two steps: the first one consists in fitting the marginal distribution of each univariate time-series, while the second one deals with the estimation of the joint distribution of the log-returns described by a RS copula model. Maximum likelihood estimation of the model parameters is carried out by the expectation-maximization (EM) algorithm, which alternates two steps until convergence: at the E-step, we compute the expectation of the log-likelihood evaluated using the current values for the parameters and, at the M-step, parameters estimates are updated by maximizing the expected complete-data log-likelihood computed at the previous step. The main computational burdens deal with estimating the correlation matrix (R) and the number of degrees of freedom (v) of the Student t-copula. At this aim, we propose performing the M-step by computing R given v using a closed form solution obtained from a constrained optimization of the log-likelihood using Lagrange multipliers. Then, we numerically maxim

Published
2022

36. The diurnal cycle of water ice on comet 67P/Churyumov-Gerasimenko

Author

De Sanctis, M. C., Capaccioni, F., Ciarniello, M., Filacchione, G., Formisano, M., Mottola, S., Raponi, A., Tosi, F., Bockelée-Morvan, D., Erard, S., Leyrat, C., Schmitt, B., Ammannito, E., Arnold, G., Barucci, M. A., Combi, M., Capria, M. T., Cerroni, P., Ip, W.-H., Kuehrt, E., McCord, T. B., Palomba, E., Beck, P., Quirico, E., Piccioni, G., Bellucci, G., Fulchignoni, M., Jaumann, R., Stephan, K., Longobardo, A., Mennella, V., Migliorini, A., Benkhoff, J., Bibring, J. P., Blanco, A., Blecka, M., Carlson, R., Carsenty, U., Colangeli, L., Combes, M., Crovisier, J., Drossart, P., Encrenaz, T., Federico, C., Fink, U., Fonti, S., Irwin, P., Langevin, Y., Magni, G., Moroz, L., Orofino, V., Schade, U., Taylor, F., Tiphene, D., Tozzi, G. P., Biver, N., Bonal, L., Combe, J.-Ph., Despan, D., Flamini, E., Fornasier, S., Frigeri, A., Grassi, D., Gudipati, M. S., Mancarella, F., Markus, K., Merlin, F., Orosei, R., Rinaldi, G., Cartacci, M., Cicchetti, A., Giuppi, S., Hello, Y., Henry, F., Jacquinod, S., Reess, J. M., Noschese, R., Politi, R., and Peter, G.

Subjects
Water cycle -- Natural history -- Observations, Comets -- Natural history -- Observations, Environmental issues, Science and technology, Zoology and wildlife conservation
Abstract

Author(s): M. C. De Sanctis (corresponding author) [1]; F. Capaccioni [1]; M. Ciarniello [1]; G. Filacchione [1]; M. Formisano [1]; S. Mottola [2]; A. Raponi [1]; F. Tosi [1]; D. [...]

Published
2015
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37. Spectroscopic Characterization of Mineralogy and Its Diversity Across Vesta

Author

De Sanctis, M. C., Ammannito, E., Capria, M. T., Tosi, F., Capaccioni, F., Zambon, F., Carraro, F., Fonte, S., Frigeri, A., Jaumann, R., Magni, G., Marchi, S., McCord, T. B., McFadden, L. A., McSween, H. Y., Mittlefehldt, D. W., Nathues, A., Palomba, E., Pieters, C. M., Raymond, C. A., Russell, C. T., Toplis, M. J., and Turrini, D.

Published
2012
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38. The Surface Composition and Temperature of Asteroid 21 Lutetia As Observed by Rosetta/VIRTIS

Author

Coradini, A., Capaccioni, F., Erard, S., Arnold, G., De Sanctis, M. C., Filacchione, G., Tosi, F., Barucci, M. A., Capria, M. T., Ammannito, E., Grassi, D., Piccioni, G., Giuppi, S., Bellucci, G., Benkhoff, J., Bibring, J. P., Blanco, A., Blecka, M., Bockelee-Morvan, D., Carraro, F., Carlson, R., Carsenty, U., Cerroni, P., Colangeli, L., Combes, M., Combi, M., Crovisier, J., Drossart, P., Encrenaz, E. T., Federico, C., Fink, U., Fonti, S., Giacomini, L., Ip, W. H., Jaumann, R., Kuehrt, E., Langevin, Y., Magni, G., McCord, T., Mennella, V., Mottola, S., Neukum, G., Orofino, V., Palumbo, P., Schade, U., Schmitt, B., Taylor, F., Tiphene, D., and Tozzi, G.

Published
2011

39. LHC EFT WG Report: Experimental Measurements and Observables

Author

Nuno Castro, Cranmer, K., Gritsan, A. V., Howarth, J., Magni, G., Mimasu, K., Rojo, J., Roskes, J., Vryonidou, E., and You, T.

Subjects
High Energy Physics - Experiment (hep-ex), High Energy Physics - Phenomenology, High Energy Physics - Phenomenology (hep-ph), FOS: Physical sciences, High Energy Physics - Experiment, Particle Physics - Phenomenology
Abstract

The LHC effective field theory working group gathers members of the LHC experiments and the theory community to provide a framework for the interpretation of LHC data in the context of EFT. In this note we discuss experimental observables and corresponding measurements in analysis of the Higgs, top, and electroweak data at the LHC. We review the relationship between operators and measurements relevant for the interpretation of experimental data in the context of a global SMEFT analysis. One of the goals of ongoing effort is bridging the gap between theory and experimental communities working on EFT, and in particular concerning optimised analyses. This note serves as a guide to experimental measurements and observables leading to EFT fits and establishes good practice, but does not present authoritative guidelines how those measurements should be performed., LHC EFT Working Group note, 55 pages, 17 figures

Published
2022

40. Exploring the Martian Subsurface with Ma_MISS EXOMARS 2022

Author

De Sanctis, C.M., Altieri, F., Ammanito, Eleonora, De Angelis, Simone, Ehlmann, B, Ferrari, M., Frigeri, A., Fonte, S., Formisano, M., Apuzzo, A., Brossier, Jérémy F., Costa, N., Rossi, L., Vizzini, G., Giardino, M., Mugnuolo, R., Pirrotta, Simone, Bibring, J-.P., Di Iorio, T., Cappacioni, F., Capria, M. T., Ciarletti, V., Cousins, Claire R, Ercoli Finzi, Amalia, Federico, C., Magni, G., Korablev, O., Lavagna, Michèle, Mantsevich, S., Piccioni, G., Stephan, Katrin, and Westall, F.

Subjects
Mars, Ma_MISS, Exomars
Published
2022

43. Snowmass 2021 Whitepaper: Proton Structure at the Precision Frontier

Author

Amoroso, S., primary, Apyan, A., additional, Armesto, N., additional, Ball, R.D., additional, Bertone, V., additional, Bissolotti, C., additional, Blümlein, J., additional, Boughezal, R., additional, Bozzi, G., additional, Britzger, D., additional, Buckley, A., additional, Candido, A., additional, Carrazza, S., additional, Celiberto, F.G., additional, Cerci, S., additional, Chachamis, G., additional, Cooper-Sarkar, A.M., additional, Courtoy, A., additional, Cridge, T., additional, Cruz-Martinez, J.M., additional, Giuli, F., additional, Guzzi, M.G., additional, Gwenlan, C., additional, Harland-Lang, L.A., additional, Hekhorn, F., additional, Hentschinski, M., additional, Hobbs, T.J., additional, Hoeche, S., additional, Huss, A., additional, Huston, J., additional, Jadach, S., additional, Jalilian-Marian, J., additional, Klein, M., additional, Krintiras, G.K., additional, Lin, H.-W., additional, Loizides, C., additional, Magni, G., additional, Malaescu, B., additional, Mistlberger, B., additional, Moch, S., additional, Nadolsky, P.M., additional, Nocera, E.R., additional, Olness, F.I., additional, Petriello, F., additional, Pires, J., additional, Rabbertz, K., additional, Rojo, J., additional, Royon, C., additional, Schnell, G., additional, Schwan, C., additional, Siódmok, A., additional, Soper, D.E., additional, Sutton, M., additional, Thorne, R.S., additional, Ubiali, M., additional, Vita, G., additional, Weber, J.H., additional, Whitehead, J., additional, Xie, K., additional, Yuan, C.-P., additional, and Zhou, B., additional

Published
2022
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44. Exposed water ice on the nucleus of comet 67P/Churyumov–Gerasimenko

Author

Filacchione, G., De Sanctis, M. C., Capaccioni, F., Raponi, A., Tosi, F., Ciarniello, M., Cerroni, P., Piccioni, G., Capria, M. T., Palomba, E., Bellucci, G., Erard, S., Bockelee-Morvan, D., Leyrat, C., Arnold, G., Barucci, M. A., Fulchignoni, M., Schmitt, B., Quirico, E., Jaumann, R., Stephan, K., Longobardo, A., Mennella, V., Migliorini, A., Ammannito, E., Benkhoff, J., Bibring, J. P., Blanco, A., Blecka, M. I., Carlson, R., Carsenty, U., Colangeli, L., Combes, M., Combi, M., Crovisier, J., Drossart, P., Encrenaz, T., Federico, C., Fink, U., Fonti, S., Ip, W. H., Irwin, P., Kuehrt, E., Langevin, Y., Magni, G., McCord, T., Moroz, L., Mottola, S., Orofino, V., Schade, U., Taylor, F., Tiphene, D., Tozzi, G. P., Beck, P., Biver, N., Bonal, L., Combe, J-Ph., Despan, D., Flamini, E., Formisano, M., Fornasier, S., Frigeri, A., Grassi, D., Gudipati, M. S., Kappel, D., Mancarella, F., Markus, K., Merlin, F., Orosei, R., Rinaldi, G., Cartacci, M., Cicchetti, A., Giuppi, S., Hello, Y., Henry, F., Jacquinod, S., Reess, J. M., Noschese, R., Politi, R., and Peter, G.

Published
2016
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45. Olivine in an unexpected location on Vesta's surface

Author

Ammannito, E., De Sanctis, M.C., Palomba, E., Longobardo, A., Mittlefehldt, D.W., McSween, H.Y., Marchi, S., Capria, M.T., Capaccioni, F., Frigeri, A., Pieters, C.M., Ruesch, O., Tosi, F., Zambon, F., Fonte, S., Hiesinger, H., Magni, G., McFadden, L.A., Raymond, C.A., Russell, C.T., and Sunshine, J.M.

Subjects
Olivine -- Properties, Vesta (Asteroid) -- Natural history, Astrogeology -- Research, Earth -- Mantle, Environmental issues, Science and technology, Zoology and wildlife conservation
Abstract

Olivine is a major component of the mantle of differentiated bodies, including Earth. Howardite, eucrite and diogenite (HED) meteorites represent regolith, basaltic-crust, lower-crust and possibly ultramafic-mantle samples of asteroid Vesta, which is the lone surviving, large, differentiated, basaltic rocky protoplanet in the Solar System (1). Only a few of these meteorites, the orthopyroxene-rich diogenites, contain olivine, typically with a concentration of less than 25 per cent by volume (2). Olivine was tentatively identified on Vesta (3,4), on the basis of spectral and colour data, but other observations did not confirm its presence (5). Here we report that olivine is indeed present locally on Vesta's surface but that, unexpectedly, it has not been found within the deep, south-pole basins, which are thought to be excavated mantle rocks (6-8). Instead, it occurs as near-surface materials in the northern hemisphere. Unlike the meteorites, the olivine-rich (more than 50 per cent by volume) material is not associated with diogenite but seems to be mixed with howardite, the most common (7,9) surface material. Olivine is exposed in crater walls and in ejecta scattered diffusely over a broad area. The size of the olivine exposures and the absence of associated diogenite favour a mantle source, but the exposures are located far from the deep impact basins. The amount and distribution of observed olivine-rich material suggest a complex evolutionary history for Vesta., The Visible and Infrared Mapping Spectrometer (VIR) on board NASA's Dawn spacecraft (10) has been used in a global search for olivine on the Vestan surface (Supplementary Information). VIR revealed [...]

Published
2013

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