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Building renovation is a key initiative to promote energy efficiency, the integration of renewable energy sources (RESs), and a reduction in CO2 emissions. Supporting these goals, emerging research is dedicated to energy communities and positive energy districts. In this work, an urban neighborhood of six buildings in Trento (Italy) is considered. Firstly, the six buildings are modeled with the Urban Modeling Interface tool to evaluate the energy performances in 2024 and 2050, also accounting for the different climatic conditions for these two time periods. Energy demands for space heating, domestic hot water, space cooling, electricity, and transport are computed. Then, EnergyPLAN coupled with a multi-objective evolutionary algorithm is used to investigate 12 different energy decarbonization scenarios in 2024 and 2050 based on different boundaries for RESs, energy storage, hydrogen, energy system integration, and energy community incentives. Two conflicting objectives are considered: cost and CO2 emission reductions. The results show, on the one hand, the key role of sector coupling technologies such as heat pumps and electric vehicles in exploiting local renewables and, on the other hand, the higher costs in introducing both electricity storage to approach complete decarbonization and hydrogen as an alternative strategy in the electricity, thermal, and transport sectors. As an example of the quantitative valuable finding of this work, in scenario S1 "all sectors and EC incentive" for the year 2024, a large reduction of 55% of CO2 emissions with a modest increase of 11% of the total annual cost is identified along the Pareto front. [ABSTRACT FROM AUTHOR]

In the contemporary landscape, roughly one-fourth of worldwide carbon dioxide emissions stem from industrial energy usage. In the industrial sector, improving the efficient and flexible coupling among different energy demands (electricity, heating, and cooling) and exploiting the integration of Renewable Energy Sources (RESs) and waste heat can lead to a drastic reduction in CO2 emissions, which are also the goals of the EU founded Horizon Europe FLEXIndustries project. This study aims to establish a cost-optimized decarbonization strategy for an energy-intensive industry, focusing on an Italian pharmaceutical company. It delves into the exploration of potential pathways and diverse energy mix configurations. The approach undertaken involves coupling a customized energy system simulation framework, specifically designed for the industrial site, with a Multi-Objective Evolutionary Algorithm (MOEA). The study, conducted with a focus on the year 2024, involves a comparative analysis of three distinct scenarios. Within the intricate and challenging constraints of the industrial demo site, 13 technologies are investigated. The outcomes of each scenario reveal a set of Pareto optimal solutions, which are thoroughly analyzed to discern the evolution of the energy mix along the Pareto front. These results shed light on the compelling potential of hybrid solutions, showcasing the feasibility of achieving substantial decarbonization with only moderate increases in costs. The availability of land for RES technologies, along with the existence of a biomass supply chain in the region, emerge as pivotal determinants. [ABSTRACT FROM AUTHOR]

A case of disseminated histoplasmosis in a 56-year-old apparently healthy male without any history of travel to endemic zone is described. The patient presented with fever with cough, respiratory distress and disorientation. Physical findings include fever, shortness of breath, reduced level of consciousness and hypotension. Diagnosis was confirmed by presence of Histoplasma capsulatum in bone marrow aspirate. This report illustrates the importance of recognizing the possibility of histoplasmosis in Bangladesh where mimickers of histoplasmosis like pulmonary tuberculosis and visceral leishmaniasis are extremely common. [ABSTRACT FROM AUTHOR]

Oculomotor palsy is a recognized uncommon complication in herpes zoster ophthalmicus. A case of herpes zoster ophthalmicus with ophthalmoplegia is reported. A 15 year old boy presented with ptosis, chemosis, proptosis, ophthalmoplegia involving IVth and VIth cranial nerve following vesicular eruption on his right forehead. He was treated with oral acyclovir and oral steroids. He made a partial recovery with improvement of ptosis, proptosis but with residual VIth nerve palsy. [ABSTRACT FROM AUTHOR]

Tuberculosis involving the anorectal region is a rare extrapulmonary form of the disease. We report two cases of isolated rectal tuberculosis with different presentations. On both instances, diagnosis was confirmed by histological examination and treated with anti-tuberculous drugs with successful outcome. [ABSTRACT FROM AUTHOR]