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23 results on '"Mahindroo, Jaspreet"'

14. Spontaneous Emergence of Azithromycin Resistance in Independent Lineages of Salmonella Typhi in Northern India

Author

Carey, Megan E, primary, Jain, Ruby, additional, Yousuf, Mohammad, additional, Maes, Mailis, additional, Dyson, Zoe A, additional, Thu, Trang Nguyen Hoang, additional, Nguyen Thi Nguyen, To, additional, Ho Ngoc Dan, Thanh, additional, Nhu Pham Nguyen, Quynh, additional, Mahindroo, Jaspreet, additional, Thanh Pham, Duy, additional, Sandha, Kawaljeet Singh, additional, Baker, Stephen, additional, and Taneja, Neelam, additional

Published
2021
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15. Comparative analysis of virulence determinants, phylogroups, and antibiotic susceptibility patterns of typical versus atypical Enteroaggregative E. coli in India

Author

Modgil, Vinay, primary, Mahindroo, Jaspreet, additional, Narayan, Chandradeo, additional, Kalia, Manmohit, additional, Yousuf, Md, additional, Shahi, Varun, additional, Koundal, Meenakshi, additional, Chaudhary, Pankaj, additional, Jain, Ruby, additional, Sandha, Kawaljeet Singh, additional, Tanwar, Seema, additional, Gupta, Pratima, additional, Thakur, Kamlesh, additional, Singh, Digvijay, additional, Gautam, Neha, additional, Kakkar, Manish, additional, Bharti, Bhavneet, additional, Mohan, Balvinder, additional, and Taneja, Neelam, additional

Published
2020
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16. Spontaneous emergence of azithromycin resistance in independent lineages of Salmonella Typhi in Northern India

Author

Carey, Megan E., primary, Jain, Ruby, additional, Yousuf, Mohammad, additional, Maes, Mailis, additional, Dyson, Zoe A., additional, Thu, Trang Nguyen Hoang, additional, Nguyen, To Nguyen Thi, additional, Dan, Thanh Ho Ngoc, additional, Nguyen, Quynh Nhu Pham, additional, Mahindroo, Jaspreet, additional, Pham, Duy Thanh, additional, Sandha, Kawaljeet Singh, additional, Baker, Stephen, additional, and Taneja, Neelam, additional

Published
2020
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21. Phenotypic and genotypic characterization of antimicrobial resistance in clinical isolates of Vibrio choleraeover a decade (2002-2016)

Author

Gupta, Parakriti, Modgil, Vinay, Kant, Vishal, Kaur, Harpreet, Narayan, Chandradeo, Mahindroo, Jaspreet, Verma, Ritu, Mohan, Balvinder, and Taneja, Neelam

Abstract

Emergence and spread of resistance among Vibrio choleraehave become a global public health problem. In India, no consolidated data is available on antimicrobial susceptibility patterns and antibiotic resistance genes.

Published
2021
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22. Extensively Drug-Resistant Klebsiella pneumoniae Associated with Complicated Urinary Tract Infection in Northern India.

Author

Kaza P, Xavier BB, Mahindroo J, Singh N, Baker S, Nguyen TNT, Mavuduru RS, Mohan B, and Taneja N

Subjects
Humans, Colistin pharmacology, Klebsiella pneumoniae, Anti-Bacterial Agents pharmacology, beta-Lactamases genetics, beta-Lactamases pharmacology, Microbial Sensitivity Tests, Bacterial Proteins genetics, Bacterial Proteins pharmacology, Klebsiella Infections epidemiology, Urinary Tract Infections epidemiology
Abstract

Klebsiella pneumoniae (Kp), which is associated with hospital-acquired infections, is extensively drug-resistant (XDR), making treatment difficult. Understanding the genetic epidemiology of XDR-Kp can help determine its potential to be hypervirulent (hv) through the presence of siderophores. We characterized the genomes of 18 colistin-resistant XDR-Kp isolated from 14 patients with complicated tract infection at an Indian healthcare facility. The 18 organisms comprised the following sequence types (STs): ST14 (n = 9), ST147 (n = 5), ST231 (n = 2), ST2096 (n = 1), and ST25 (n = 1). Many patients in each ward were infected with the same ST, suggesting a common source of infection. Some patients had recurrent infections with multiple STs circulating in the ward, providing evidence of hospital transmission. β-lactamase genes (bla CTX-M-1 , bla SHV , and bla ampH ) were present in all isolates. bla NDM-1 was present in 15 isolates, bla OXA-1 in 16 isolates, bla TEM-1D in 13 isolates, and bla OXA-48 in 3 isolates. Disruption of mgrB by various insertion sequences was responsible for colistin resistance in 6 isolates. The most common K-type among isolates was K2 (n = 10). One XDR convergent hvKp ST2096 mutation (iuc+ybt+bla OXA-1 +bla OXA-48 ) was associated with prolonged hospitalization. Convergent XDR-hvKp has outbreak potential, warranting effective antimicrobial stewardship and infection control.

Published
2024
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23. Endemic fluoroquinolone-resistant Salmonellaenterica serovar Kentucky ST198 in northern India.

Author

Mahindroo J, Thanh DP, Nguyen TNT, Mohan B, Thakur S, Baker S, and Taneja N

Subjects
Animals, Anti-Bacterial Agents therapeutic use, Ciprofloxacin therapeutic use, DNA, Bacterial genetics, Humans, India epidemiology, Phylogeny, Salmonella Infections, Animal drug therapy, Salmonella enterica classification, Salmonella enterica genetics, Serogroup, Whole Genome Sequencing, Anti-Bacterial Agents pharmacology, Ciprofloxacin pharmacology, Drug Resistance, Bacterial, Salmonella Infections, Animal epidemiology, Salmonella Infections, Animal microbiology, Salmonella enterica drug effects, Salmonella enterica isolation & purification
Abstract

Salmonellaenterica serovar Kentucky is an emergent human pathogen. Human infection with ciprofloxacin-resistant S. enterica Kentucky ST198 has been reported in Europe and North America as a consequence of travel to Asia/the Middle East. This is, to the best of our knowledge, the first study reporting the identification of this epidemic clone in India and South Asia.

Published
2019
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