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6. Streptococcal bacterial components in cancer therapy

Author

Marzhoseyni, Zeynab, Shojaie, Layla, Tabatabaei, Seyed Alireza, Movahedpour, Ahmad, Safari, Mahmood, Esmaeili, Davoud, Mahjoubin-Tehran, Maryam, Jalili, Amin, Morshedi, Korosh, Khan, Haroon, Okhravi, Ranaa, Hamblin, Michael R., and Mirzaei, Hamed

Published
2022
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9. Nanospheres for curcumin delivery as a precision nanomedicine in cancer therapy.

Author

Mahjoubin-Tehran, Maryam, Rezaei, Samaneh, Kesharwani, Prashant, and Sahebkar, Amirhossein

Subjects
*CURCUMIN, *NANOMEDICINE, *METHYL methacrylate, *CANCER treatment, *GLYCOLIC acid, *LACTIC acid
Abstract

AbstractCancer is ranked among the top causes of mortality throughout the world. Conventional therapies are associated with toxicity and undesirable side effects, rendering them unsuitable for prolonged use. Additionally, there is a high occurrence of resistance to anticancer drugs and recurrence in certain circumstances. Hence, it is essential to discover potent anticancer drugs that exhibit specificity and minimal unwanted effects. Curcumin, a polyphenol derivative, is present in the turmeric plant (Curcuma longa L.) and has chemopreventive, anticancer, radio-, and chemo-sensitizing activities. Curcumin exerts its anti-tumor effects on cancer cells by modulating the disrupted cell cycle through p53-dependent, p53-independent, and cyclin-dependent mechanisms. This review provides a summary of the formulations of curcumin based on nanospheres, since there is increasing interest in its medicinal usage for treating malignancies and tumors. Nanospheres are composed of a dense polymeric matrix, and have a size ranging from 10 to 200 nm. Lactic acid polymers, glycolic acid polymers, or mixtures of them, together with poly (methyl methacrylate), are primarily used as matrices in nanospheres. Nanospheres are suitable for local, oral, and systemic delivery due to their minuscule particle size. The majority of nanospheres are created using polymers that are both biocompatible and biodegradable. Previous investigations have shown that the use of a nanosphere delivery method can enhance tumor targeting, therapeutic efficacy, and biocompatibility of different anticancer agents. Moreover, these nanospheres can be easily taken up by mammalian cells. This review discusses the many curcumin nanosphere formulations used in cancer treatment. [ABSTRACT FROM AUTHOR]

Published
2024
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13. Cell death pathways and viruses: Role of microRNAs

Author

Sadri Nahand, Javid, Shojaie, Layla, Akhlagh, Seyed Amirreza, Ebrahimi, Mohammad Saeid, Mirzaei, Hamid Reza, Bannazadeh Baghi, Hossein, Mahjoubin-Tehran, Maryam, Rezaei, Nima, Hamblin, Michael R., Tajiknia, Vida, Rahimian, Neda, and Mirzaei, Hamed

Published
2021
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18. CXCL-10: a new candidate for melanoma therapy?

Author

Bagheri, Hossein, Pourhanifeh, Mohammad Hossein, Derakhshan, Maryam, Mahjoubin-Tehran, Maryam, Ghasemi, Faezeh, Mousavi, Shabnam, Rafiei, Rouhollah, Abbaszadeh-Goudarzi, Kazem, Mirzaei, Hamid Reza, and Mirzaei, Hamed

Published
2020
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24. Autophagy and gastrointestinal cancers: the behind the scenes role of long non-coding RNAs in initiation, progression, and treatment resistance

Author

Shafabakhsh, Rana, Arianfar, Farzaneh, Vosough, Massoud, Mirzaei, Hamid Reza, Mahjoubin-Tehran, Maryam, khanbabaei, Hashem, Kowsari, Hamed, Shojaie, Layla, Azar, Maryam Ebadi Fard, Hamblin, Michael R., and Mirzaei, Hamed

Abstract

Gastrointestinal (GI) cancers comprise a heterogeneous group of complex disorders that affect different organs, including esophagus, stomach, gallbladder, liver, biliary tract, pancreas, small intestine, colon, rectum, and anus. Recently, an explosion in nucleic acid-based technologies has led to the discovery of long non-coding RNAs (lncRNAs) that have been found to possess unique regulatory functions. This class of RNAs is >200 nucleotides in length, and is characterized by their lack of protein coding. LncRNAs exert regulatory effects in GI cancer development by affecting different functions such as the proliferation and metastasis of cancer cells, apoptosis, glycolysis and angiogenesis. Over the past few decades, considerable evidence has revealed the important role of autophagy in both GI cancer progression and suppression. In addition, recent studies have confirmed a significant correlation between lncRNAs and the regulation of autophagy. In this review, we summarize how lncRNAs play a behind the scenes role in the pathogenesis of GI cancers through regulation of autophagy.

Published
2024
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30. Non-coding RNAs and glioblastoma: Insight into their roles in metastasis

Author

Mousavi, Seyed Mojtaba, primary, Derakhshan, Maryam, additional, Baharloii, Fatereh, additional, Dashti, Fatemeh, additional, Mirazimi, Seyed Mohammad Ali, additional, Mahjoubin-Tehran, Maryam, additional, Hosseindoost, Saereh, additional, Goleij, Pouya, additional, Rahimian, Neda, additional, Hamblin, Michael R., additional, and Mirzaei, Hamed, additional

Published
2022
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31. Platinum Nanoparticles in Biomedicine: Preparation, Anti-Cancer Activity, and Drug Delivery Vehicles

Author

Abed, Atena, primary, Derakhshan, Maryam, additional, Karimi, Merat, additional, Shirazinia, Matin, additional, Mahjoubin-Tehran, Maryam, additional, Homayonfal, Mina, additional, Hamblin, Michael R, additional, Mirzaei, Seyed Abbas, additional, Soleimanpour, Hamidreza, additional, Dehghani, Sadegh, additional, Dehkordi, Farnaz Farzaneh, additional, and Mirzaei, Hamed, additional

Published
2022
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32. Gynecologic Cancer, Cancer Stem Cells, and Possible Targeted Therapies

Author

Keyvani, Vahideh, primary, Riahi, Espanta, additional, Yousefi, Meysam, additional, Esmaeili, Seyed-Alireza, additional, Shafabakhsh, Rana, additional, Moradi Hasan-Abad, Amin, additional, Mahjoubin-Tehran, Maryam, additional, Hamblin, Michael R., additional, Mollazadeh, Samaneh, additional, and Mirzaei, Hamed, additional

Published
2022
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36. Antimetastatic Effects of Curcumin in Oral and Gastrointestinal Cancers

Author

Davoodvandi, Amirhossein, primary, Farshadi, Marjan, additional, Zare, Noushid, additional, Akhlagh, Seyed Amirreza, additional, Alipour Nosrani, Esmail, additional, Mahjoubin-Tehran, Maryam, additional, Kangari, Parisa, additional, Sharafi, Seyedeh Maryam, additional, Khan, Haroon, additional, Aschner, Michael, additional, Baniebrahimi, Ghazaleh, additional, and Mirzaei, Hamed, additional

Published
2021
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40. Streptococcal bacterial components in cancer therapy

Author

Marzhoseyni, Zeynab, primary, Shojaie, Layla, additional, Tabatabaei, Seyed Alireza, additional, Movahedpour, Ahmad, additional, Safari, Mahmood, additional, Esmaeili, Davoud, additional, Mahjoubin-Tehran, Maryam, additional, Jalili, Amin, additional, Morshedi, Korosh, additional, Khan, Haroon, additional, Okhravi, Ranaa, additional, Hamblin, Michael R., additional, and Mirzaei, Hamed, additional

Published
2021
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41. Use of Salmonella Bacteria in Cancer Therapy: Direct, Drug Delivery and Combination Approaches

Author

Badie, Fereshteh, primary, Ghandali, Maryam, additional, Tabatabaei, Seyed Alireza, additional, Safari, Mahmood, additional, Khorshidi, Ahmad, additional, Shayestehpour, Mohammad, additional, Mahjoubin-Tehran, Maryam, additional, Morshedi, Korosh, additional, Jalili, Amin, additional, Tajiknia, Vida, additional, Hamblin, Michael R., additional, and Mirzaei, Hamed, additional

Published
2021
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45. Effects of Therapeutic Probiotics on Modulation of microRNAs

Author

Davoodvandi, Amirhossein, primary, Marzban, Havva, additional, Goleij, Pouya, additional, Sahebkar, Amirhossein, additional, Morshedi, Korosh, additional, Rezaei, Samaneh, additional, mahjoubin-Tehran, maryam, additional, Tarrahimofrad, Hossein, additional, Hamblin, Michael R, additional, and Mirzaei, Hamed, additional

Published
2020
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47. Contributors

Author

Abbasi-Kolli, Mohammad, Abdullah, Ahmad, Saeed, Ahmed, Imad, Akhtar, Muhammad Furqan, Al-Ghamdi, Mariam S., Al-Harrasi, Ahmed, Alam, Waqas, Ali, Arif, Ali, Gowhar, Ali, Mubarika, Alothaim, Abdul Aziz S., Althobaiti, Nora A., Aly, Shaza H., Aman, Waqar, Asif, Muhammad, Azhdari, Sara, Bayat, Mobina, Blundell, Renald, Chauhdary, Zunera, Ebrahimi, Mohammad Saeid, Eldahshan, Omayma A., Fayed, Marwa A.A., Hosseini, Zohreh, Hussain, Yaseen, Islam, Waseem ul, Kabir, Md. Tanvir, Khan, Faizullah, Khan, Fazlullah, Khan, Haroon, Khatami, Alireza, Khayami, Reza, Kouchaki, Ebrahim, Mahjoubin-Tehran, Maryam, Malik, Abd, Martins, Alice Maria Costa, Mirzaei, Hamed, Modiri, Navid, Moghoofei, Mohsen, Morshedi, Korosh, Mostafa, Nada M., Naveed, Aamir, Qasim, Muhammad, Rahman, Md. Habibur, Rahman, Shaikh Mizanoor, Rashad, Muhammad, Rasul, Azhar, Refaey, Mohamed S., Rezaei, Samaneh, Saadullah, Malik, Sadri Nahand, Javid, Saleem, Ammara, Saleem, Mohammad, Saleem, Uzma, Salmaninejad, Arash, Samadi-khouzani, Abbas, Shafabakhsh, Rana, Shah, Muhammad Ajmal, Siddique, Rida, Siddiqui, Muhammad Faisal, Taghizadieh, Mohammad, Taheri, Forough, ur Rehman, Maqsood, and Waqas, Muhammad

Published
2023
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48. comprehensive review of online resources for microRNA–diseases associations: the state of the art.

Author

Mahjoubin-Tehran, Maryam, Rezaei, Samaneh, Jalili, Amin, Sahebkar, Amirhossein, and Aghaee-Bakhtiari, Seyed Hamid

Subjects
*NON-coding RNA, *ART associations, *CONSUMERS' reviews, *ARTS associations, *MICRORNA
Abstract

MicroRNAs (miRNAs) as small 19- to 24-nucleotide noncoding RNAs regulate several mRNA targets and signaling pathways. Therefore, miRNAs are considered key regulators in cellular pathways as well as various pathologies. There is substantial interest in the relationship between disease and miRNAs, which made that one of the important research topics. Interestingly, miRNAs emerged as an attractive approach for clinical application, not only as biomarkers for diagnosis and prognosis or in the prediction of therapy response but also as therapeutic tools. For these purposes, the identification of crucial miRNAs in disease is very important. Databases provided valuable experimental and computational miRNAs–disease information in an accessible and comprehensive manner, such as miRNA target genes, miRNA related in signaling pathways and miRNA involvement in various diseases. In this review, we summarized miRNAs–disease databases in two main categories based on the general or specific diseases. In these databases, researchers could search diseases to identify critical miRNAs and developed that for clinical applications. In another way, by searching particular miRNAs, they could recognize in which disease these miRNAs would be dysregulated. Despite the significant development that has been done in these databases, there are still some limitations, such as not being updated and not providing uniform and detailed information that should be resolved in future databases. This survey can be helpful as a comprehensive reference for choosing a suitable database by researchers and as a guideline for comparing the features and limitations of the database by developer or designer. Short abstract We summarized miRNAs–disease databases that researchers could search disease to identify critical miRNAs and developed that for clinical applications. This survey can help choose a suitable database for researchers. [ABSTRACT FROM AUTHOR]

Published
2022
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49. Circular RNAs: New Epigenetic Signatures in Viral Infections

Author

Nahand, Javid Sadri, primary, Jamshidi, Sogol, additional, Hamblin, Michael R., additional, Mahjoubin-Tehran, Maryam, additional, Vosough, Massoud, additional, Jamali, Marzieh, additional, Khatami, Alireza, additional, Moghoofei, Mohsen, additional, Baghi, Hossein Bannazadeh, additional, and Mirzaei, Hamed, additional

Published
2020
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50. Exosomal miRNAs: novel players in viral infection

Author

Nahand, Javid Sadri, primary, Mahjoubin-Tehran, Maryam, additional, Moghoofei, Mohsen, additional, Pourhanifeh, Mohammad Hossein, additional, Mirzaei, Hamid Reza, additional, Asemi, Zatollah, additional, Khatami, Alireza, additional, Bokharaei-Salim, Farah, additional, Mirzaei, Hamed, additional, and Hamblin, Michael R, additional

Published
2020
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