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444 results on '"Maitre, Bernard"'

1. Anti–IL-4R versus anti–IL-5/5R after anti–IL-5/5R failure in asthma: An emulated target trial

Author

Devouassoux, G., Taillé, C., Chanez, P., Bonniaud, P., Bourdin, A., Saint Raymond, C., Maurer, C., Beurnier, A., Roux, P., Margelidon, V., Boudjemaa, A., Mangiapan, G., Freymond, N., Didi, T., Russier, M., Garcia, G., Meyer, E. Popin, Dupin, C., Fouquet, F., Jouveshomme, S., Gaspard, W., Dury, S., Maillard, S. Habib, Izadifar, A., Cuvillon, E., Deslée, G., Barnig, C., Perotin, J.M., Gamez, A.S., Oster, J.P., Khayat, N., Chenivesse, C., Li, X., Appere de Vecchi, C., Gicquello, A., Rami, H., Vignal, G., Just, N., Blanc, X., Leroyer, C., Wemeau, L., Achkar, A., Sattler, C., Catherinot, E., Guilleminault, L., Gaillot-Drevon, M., Rochefort-Morel, C., Couturaud, F., Martin, P., Chabrol, A., Pegliasco, H., Sése, L., Romanet, S., Caverstri, B., Tcherakian, C., Magnan, A., Ahmed, E., Allibe, F., Beltramo, G., Michaux, K., Paleiron, N., Martinez, S., Begne, C., Tummino, C., Givel, C., Mourin, G., Salvator, H., Volpato, M., Drucbert, M., Rossignoli, N., Keddache, S., Justet, A., Andrejak, C., Valcke, J., Perrin, J., Mercy, M., Jouvenot, M., Soumagne, T., Elharrar, X., Douvry, B., Godbert, B., Maitre, B., Goyard, C., Didier, A., Cadet, E., Chabot, F., Gonzalez, J., Mattei, L., Gouitaa, M., Chauveau, S., Raymond, S., Dirou, S., Fry, S., Briault, A., Moui, A., Paris, A., NoelSavina, E., Olivier, C., Caradec, E., Roche, N., Picart, G., Belmont, L., Portel, L., Serra, M. Rocca, Guibert, N., Jean, R., Hadjadj, S., Guillo, S., Gauquelin, L., Estellat, C., Prigent, A., Larrousse, M., Jaffuel, D., Bourayou, Karima, Klising, Eve, Yelles, Nessima, Pochon, Sarra, Gouider, Amal, Medina, Hadj Kaci, Yasmine, Sellali, Djouher, Dahmani, Ndao, Diakhou, Vacher, Yannick, Achkar, Antoine, Ahmed, Engi, Alain, Didier, Allibe, Flora, Andrejak, Claire, De Vecchi, Corinne Appere, Barnig, Cindy, Begne, Camille, Belmont, Laure, Beltramo, Guillaume, Blanc, Xavier, Briault, Amandine, Cadet, Emmanuelle, Caradec, Emmanuela, Catherinot, Émilie, Cavestri, Beatrice, Chabrol, Alexandre, Chanez, Pascal, Chauveau, Simon, Couturaud, Francis, Cuvillon, Édouard, Deslee, Gaëtan, Didi, Toufik, Dirou, Stéphanie, Douvry, benoît, Drucbert, Mélanie, Dupin, Clairelyne, Dury, Sandra, Elharrar, Xavier, Fouquet, Helen, Freymond, Nathalie, Fry, Stéphanie, Gaillot-Drevon, Maud, Gamez, Anne Sophie, Garcia, Gilles, Gaspard, Wanda, Gicquello, Alice, Givel, Claire, Godbert, benoit, Gonzalez, Jésus, Gouitaa, Marion, Goupil, François, Goyard, Céline, Guibert, Nicolas, Guilleminault, Laurent, Habib-Maillard, Stéphanie, Hadjadj, Samra, Izadifar, Armine, Jean, Romain, Jouvenot, marie, Jouveshomme, Stéphane, Just, Nicolas, Justet, Aurélien, Keddache, Sophia, Khayath, Naji, Lemaire, Bertrand, Leroyer, Christophe, Li, Xing, Magnan, Antoine, Maitre, Bernard, Mangiapan, Gilles, Margelidon, Victor, Martin, Pascale, Martinez, Stéphanie, Mattei, Laura, Maurer, Cyril, Mercy, Magalie, Michaux, Karine, Moui, Antoine, Mourin, Gisèle, Noel-Savina, Elisa, Olivier, Cécile, Oster, Jean-Philippe, Paleiron, Nicolas, Paris, Audrey, Pegliasco, Hervé, Perotin Collard, Jeanne-Marie, Perrin, Julie, Picart, Gaël, Pison, Christophe, Popin-Meyer, Élisabeth, Portel, Laurent, Rami, Hassina, Raymond, Stéphane, Serra, Mireille Rocca, Rochefort-Morel, Cécile, Romanet, Stéphanie, Rossignoli, Nadine, Roux, Pauline, Russier, Maud, Saint-Raymond, Christel, Salmeron, Sergio, Salvator, Helene, Sattler, Caroline, Sese, Lucile, Soumagne, Thibaud, Tcherakian, Colas, Tiotiu, Angélica, Tummino, Céline, Valcke-Brossollet, Judith, Vignal, Guillaume, Volpato, Mathilde, Wemeau, Lidwine, Valery, Solène, Simon-Tillaux, Noémie, Devouassoux, Gilles, Bonniaud, Philippe, Beurnier, Antoine, Boudjemaa, Amel, Chenivesse, Cécile, Bourdin, Arnaud, Gauquelin, Lisa, Guillo, Sylvie, Taillé, Camille, and Estellat, Candice

Published
2024
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2. SPLF/SMFU/SRLF/SFAR/SFCTCV Guidelines for the management of patients with primary spontaneous pneumothorax

Author

Jouneau, Stéphane, Ricard, Jean-Damien, Seguin-Givelet, Agathe, Bigé, Naïke, Contou, Damien, Desmettre, Thibaut, Hugenschmitt, Delphine, Kepka, Sabrina, Le Gloan, Karinne, Maitre, Bernard, Mangiapan, Gilles, Marchand-Adam, Sylvain, Mariolo, Alessio, Marx, Tania, Messika, Jonathan, Noël-Savina, Elise, Oberlin, Mathieu, Palmier, Ludovic, Perruez, Morgan, Pichereau, Claire, Roche, Nicolas, Garnier, Marc, and Martinez, Mikaël

Published
2023
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3. International survey among hepatologists and pulmonologists on the hepatic hydrothorax: plea for recommendations

Author

Cadranel, Jean-François David, Ollivier-Hourmand, Isabelle, Cadranel, Jacques, Thevenot, Thierry, Zougmore, Honoré, Nguyen-Khac, Eric, Bureau, Christophe, Allaire, Manon, Nousbaum, Jean-Baptiste, Loustaud-Ratti, Véronique, Causse, Xavier, Sogni, Philippe, Hanslik, Bertrand, Bourliere, Marc, Peron, Jean-Marie, Ganne-Carrie, Nathalie, Dao, Thong, Thabut, Dominique, Maitre, Bernard., Debzi, Nabil, Smadhi, Ryad, Sombie, Roger, Kpossou, Raimi, Nouel, Olivier, Bissonnette, Julien, Ruiz, Isaac, Medmoun, Mourad, Dastis, Sergio Negrin, Deltenre, Pierre, Artru, Florent, Raherison, Chantal, Elkrief, Laure, and Lemagoarou, Tristan

Published
2023
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4. SPLF/SMFU/SRLF/SFAR/SFCTCV Guidelines for the management of patients with primary spontaneous pneumothorax: Endorsed by the French Speaking Society of Respiratory Diseases (SPLF), the French Society of Emergency Medicine (SFMU), the French Intensive Care Society (SRLF), the French Society of Anesthesia & Intensive Care Medicine (SFAR) and the French Society of Thoracic and Cardiovascular Surgery (SFCTCV)

Author

Jouneau, Stéphane, Ricard, Jean-Damien, Seguin-Givelet, Agathe, Bigé, Naïke, Contou, Damien, Desmettre, Thibaut, Hugenschmitt, Delphine, Kepka, Sabrina, Gloan, Karinne Le, Maitre, Bernard, Mangiapan, Gilles, Marchand-Adam, Sylvain, Mariolo, Alessio, Marx, Tania, Messika, Jonathan, Noël-Savina, Elise, Oberlin, Mathieu, Palmier, Ludovic, Perruez, Morgan, Pichereau, Claire, Roche, Nicolas, Garnier, Marc, and Martinez, Mikaël

Published
2023
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7. Beyond lung cancer screening, an opportunity for early detection of chronic obstructive pulmonary disease and cardiovascular diseases.

Author

Gendarme, Sébastien, Maitre, Bernard, Hanash, Sam, Pairon, Jean-Claude, Canoui-Poitrine, Florence, and Chouaïd, Christos

Abstract

Background Lung cancer screening programs concern smokers at risk for cardiovascular diseases (CVDs) and chronic obstructive pulmonary disease (COPD). The LUMASCAN (LUng Cancer Screening, MArkers and low-dose computed tomography SCANner) study aimed to evaluate the acceptability and feasibility of screening for these 3 diseases in a community population with centralized organization and to determine low-dose computed tomography (CT) markers associated with each disease. Methods This cohort enrolled participants meeting National Comprehensive Cancer Network criteria (v1.2014) in an organized lung cancer–screening program including low-dose CT scans; spirometry; evaluations of coronary artery calcifications (CACs); and a smoking cessation plan at inclusion, 1, and 2 years; then telephone follow-up. Outcomes were the participation rate and the proportion of participants affected by lung cancer, obstructive lung disease, or CVD events. Logistic-regression models were used to identify radiological factors associated with each disease. Results Between 2016 and 2019, a total of 302 participants were enrolled: 61% men; median age 58.8 years; 77% active smoker; 11% diabetes; 38% hypertension; and 27% taking lipid-lowering agents. Inclusion, 1-year, and 2-year participation rates were 99%, 81%, 79%, respectively. After a median follow-up of 5.81 years, screenings detected 12 (4%) lung cancer, 9 of 12 via low-dose CT (78% localized) and 3 of 12 during follow-up (all stage IV), 83 (27%) unknown obstructive lung disease, and 131 (43.4%) moderate to severe CACs warranting a cardiology consultation. Preexisting COPD and moderate to severe CACs were associated with major CVD events with odds ratios of 1.98 (95% confident interval [CI] = 1.00 to 3.88) and 3.27 (95% CI = 1.72 to 6.43), respectively. Conclusion The LUMASCAN study demonstrated the feasibility of combined screening for lung cancer, COPD, and CVD in a community population. Its centralized organization enabled high participation and coordination of healthcare practitioners. [ABSTRACT FROM AUTHOR]

Published
2024
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8. Low income and outcome in idiopathic pulmonary fibrosis: An association to uncover

Author

Bouvry, Diane, Brillet, Pierre Yves, Camus, Philippe, Chabrol, Juliette, Cordier, Jean François, Cracco, Christophe, Delaval, Philippe, Didier, Morgane, Duchemann, Boris, Feuillet, Sevrine, Freynet, Olivia, Gagnadoux, Frédéric, Germaud, Patrick, Gindre, Louise, Guetta, André, Haussman, Patrick, Jouneau, Stephane, Kambouchner, Marianne, Khouatra, Chahera, Lacronique, Jacques, Molard, Anita, Picard, Clément, Planes, Carole, Rosental, Paul Andrés, Sanchez, Olivier, Similowski, Thomas, Thiberville, Luc, Uzuhnan, Yurdagül, Sesé, Lucile, Caliez, Julien, Annesi-Maesano, Isabella, Cottin, Vincent, Pesce, Giancarlo, Carton, Zohra, Israel-Biet, Dominique, Crestani, Bruno, Dudoret, Stéphanie Guillot, Cadranel, Jacques, Wallaert, Benoit, Tazi, Abdellatif, Maître, Bernard, Prévot, Grégoire, Marchand-Adam, Sylvain, Hirschi, Sandrine, Dury, Sandra, Giraud, Violaine, Gondouin, Anne, Bonniaud, Philippe, Traclet, Julie, Juvin, Karine, Borie, Raphael, Bernaudin, Jean François, Valeyre, Dominique, Cavalin, Catherine, and Nunes, Hilario

Published
2021
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9. Infertility and pregnancy outcomes among adults with primary ciliary dyskinesia.

Author

Schreck, Leonie D, Pedersen, Eva S L, Dexter, Katie, Manion, Michele, Group, Living with PCD Study Advisory, Massin, Nathalie, Maitre, Bernard, Goutaki, Myrofora, and Kuehni, Claudia E

Subjects
REPRODUCTIVE technology, HIGH-risk pregnancy, CILIARY motility disorders, PREGNANCY outcomes, MALE infertility, ECTOPIC pregnancy
Abstract

STUDY QUESTION What is the prevalence of infertility and ectopic pregnancies among individuals with primary ciliary dyskinesia (PCD)? SUMMARY ANSWER We found that 39 of 50 men (78%) and 72 of 118 women (61%) with PCD were infertile and that women with PCD had an increased risk of ectopic pregnancies (7.6 per 100 pregnancies, 95% CI 4.7–12.2). WHAT IS KNOWN ALREADY PCD is a heterogeneous multiorgan disease caused by mutations in genes required for the function and structure of motile cilia. Previous studies identified a link between PCD and infertility, but original data on prevalence of infertility and risk of ectopic pregnancies, the use and efficacy of medically assisted reproduction (MAR), and the association of fertility with PCD genotype are extremely limited. STUDY DESIGN, SIZE, DURATION We performed a cross-sectional survey about fertility within the Living with PCD study (formerly COVID-PCD). Living with PCD is an international, online, participatory study that collects information directly from people with PCD. People with PCD of any age from anywhere in the world can participate in the study. At the time of the survey, 482 adults with PCD were registered within the Living with PCD study. PARTICIPANTS/MATERIALS, SETTING, METHODS We sent a questionnaire on fertility on 12 July 2022, to all participants older than 18 years enrolled in the Living with PCD study. Responses were collected until 8 March 2023. The fertility questionnaire covered topics related to pregnancy attempts, use of MAR, and pregnancy outcomes. Data were collected via the Research Electronic Data Capture (REDCap) platform. We defined infertility as failure to achieve a clinical pregnancy after 12 months or use of MAR for at least one pregnancy. MAIN RESULTS AND THE ROLE OF CHANCE In total, 265 of 482 adult participants (55%) completed the fertility questionnaire. Among 168 adults who had tried to conceive, 39 of 50 men (78%) and 72 of 118 women (61%) were infertile. Of the infertile men, 28 had tried MAR, and 17 of them (61%) fathered a child with the help of MAR. Among infertile women, 59 had used MAR, and 41 of them (69%) became pregnant with the help of MAR. In our population, women with PCD showed a relatively high risk of ectopic pregnancies: 1 in 10 women who became pregnant had at least one ectopic pregnancy and 7.6% of pregnancies were ectopic (95% CI 4.7–12.2). We evaluated the association between fertility and affected PCD genes in 46 individuals (11 men, 35 women) with available genetic and fertility information, and found differences between genotypes, e.g. all five women with a mutation in CCDC40 were infertile and all five with DNAH11 were fertile. LIMITATIONS, REASONS FOR CAUTION The study has limitations, including potential selection bias as people experiencing problems with fertility might be more likely to fill in the questionnaire, which may have influenced our prevalence estimates. We were unable to validate clinical data obtained from participant self-reports owing to the anonymous study design, which is likely to lead to recall bias. WIDER IMPLICATIONS OF THE FINDINGS The study underlines the need for addressing infertility in routine PCD care, with a focus on informing individuals with PCD about their increased risk. It emphasizes the utility and efficacy of MAR in PCD-related infertility. Additionally, women attempting conception should be made aware of the increased risk of ectopic pregnancies and seek systematic early consultation to confirm an intrauterine pregnancy. Fertility, efficacy of MAR, and risk for adverse pregnancy outcomes differ between people with PCD—depending on genotypes—and close monitoring and support might be needed from fertility specialists to increase chances of successful conception. STUDY FUNDING/COMPETING INTEREST(S) Our research was funded by the Swiss National Science Foundation, Switzerland (SNSF 320030B_192804), the Swiss Lung Association, Switzerland (2021-08_Pedersen), and we also received support from the PCD Foundation, USA; the Verein Kartagener Syndrom und Primäre Ciliäre Dyskinesie, Germany; the PCD Support UK, UK; and PCD Australia, Australia. M. Goutaki received funding from the Swiss National Science Foundation, Switzerland (PZ00P3_185923). B. Maitre participates in the RaDiCo-DCP funded by INSERM France. The study authors participate in the BEAT-PCD Clinical Research Collaboration supported by the European Respiratory Society. All authors declare no conflict of interest. TRIAL REGISTRATION NUMBER ClinicalTrials.gov ID NCT04602481. [ABSTRACT FROM AUTHOR]

Published
2024
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14. COPD after "Tabouna" Exposure: A Distinct Phenotype in Tunisian Women?

Author

Hamdi, Besma, Louhaichi, Sabrine, Jebali, Mohamed Aymen, Schlemmer, Frédéric, Maitre, Bernard, and Hamzaoui, Agnes

Subjects
CHRONIC obstructive pulmonary disease, SMOKING, TOBACCO smoke, RESPIRATORY insufficiency, OLDER patients
Abstract

Background: COPD due to exposure to combustible biomass is an increasingly recognized phenotype, particularly among women who use traditional ovens, known as 'Tabouna', for baking bread. This paper aims to investigate the clinical and functional characteristics of COPD in Tunisian female patients attributed to the use of 'Tabouna'. Methods: A retrospective single-center cohort study was conducted on patients recruited from the Department of Respiratory Disease at A. Mami Hospital, who were diagnosed with COPD between January 2014 and December 2022. The diagnosis of COPD adhered to the standards defined in GOLD 2022. Results: Out of the 95 women included in the study, 48 (50.5%) were exposed to tobacco smoke, while 47 (49.5%) were exposed to the 'Tabouna'. The median age was 70.4 ± 11.5 years, ranging from 40 to 95 years. Patients exposed to biomass were notably older, with a median age of 75.4 compared to 64.6 (p = 0.04). A significant association was observed between COPD and biomass smoke exposure, both in women residing in rural and urban areas (p = 0.006). The frequency of patients exposed to biomass with comorbidities was higher than in the group exposed to tobacco, but only hypertension showed statistically significant results (p = 0.01). Tobacco smoke induced more impairment in lung function than biomass in the group with FEV1 ≤ 30% (p = 0.04). Long-acting muscarinic antagonists were more commonly prescribed to smokers (p = 0.04). Serious complications such as chronic respiratory failure and intensive care admissions were similar in both groups (p = 0.8 and 0.4). Conclusions: COPD in women after exposure to the 'Tabouna' was observed in older patients and characterized by delayed diagnosis. Despite these clinical differences, poor COPD outcomes were similar in both groups. [ABSTRACT FROM AUTHOR]

Published
2023
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17. Prevalence and course of disease after lung resection in primary ciliary dyskinesia: a cohort & nested case-control study

Author

Kouis, Panayiotis, Goutaki, Myrofora, Halbeisen, Florian S., Gioti, Ifigeneia, Middleton, Nicos, Amirav, Israel, on behalf of the Israeli PCD Consortium, Barbato, Angelo, on behalf of the Italian PCD Consortium, Behan, Laura, Boon, Mieke, Emiralioglu, Nagehan, Haarman, Eric G., Karadag, Bulent, Koerner-Rettberg, Cordula, Lazor, Romain, on behalf of the Swiss PCD Group, Loebinger, Michael R., Maitre, Bernard, on behalf of the French Reference Centre for Rare Lung Diseases, Mazurek, Henryk, Morgan, Lucy, Nielsen, Kim Gjerum, Omran, Heymut, Özçelik, Ugur, Price, Mareike, Pogorzelski, Andrzej, Snijders, Deborah, on behalf of the PCD Italian Consortium, Thouvenin, Guillaume, on behalf of the French Reference Centre for Rare Lung Diseases, Werner, Claudius, Zivkovic, Zorica, Kuehni, Claudia E., and Yiallouros, Panayiotis K.

Published
2019
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18. Respiratory recovery trajectories after severe-to-critical COVID-19: a 1-year prospective multicentre study

Author

Schlemmer, Frédéric, primary, Valentin, Simon, additional, Boyer, Laurent, additional, Guillaumot, Anne, additional, Chabot, François, additional, Dupin, Clairelyne, additional, Le Guen, Pierre, additional, Lorillon, Gwenael, additional, Bergeron, Anne, additional, Basille, Damien, additional, Delomez, Julia, additional, Andrejak, Claire, additional, Bonnefoy, Valentine, additional, Goussault, Hélène, additional, Assié, Jean-Baptiste, additional, Choinier, Pascaline, additional, Ruppert, Anne-Marie, additional, Cadranel, Jacques, additional, Mennitti, Maria Chiara, additional, Roumila, Mehdi, additional, Colin, Charlotte, additional, Günther, Sven, additional, Sanchez, Olivier, additional, Gille, Thomas, additional, Sésé, Lucile, additional, Uzunhan, Yurdagul, additional, Faure, Morgane, additional, Patout, Maxime, additional, Morelot-Panzini, Capucine, additional, Laveneziana, Pierantonio, additional, Zysman, Maeva, additional, Blanchard, Elodie, additional, Raherison-Semjen, Chantal, additional, Giraud, Violaine, additional, Giroux-Leprieur, Etienne, additional, Habib, Stéfanie, additional, Roche, Nicolas, additional, Dinh-Xuan, Anh Tuan, additional, Sifaoui, Islem, additional, Brillet, Pierre-Yves, additional, Jung, Camille, additional, Boutin, Emmanuelle, additional, Layese, Richard, additional, Canoui-Poitrine, Florence, additional, and Maitre, Bernard, additional

Published
2023
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22. Impact of the COVID-19 pandemic and associated lockdown measures on the management, health, and behavior of the cystic fibrosis population in France during 2020 (MUCONFIN)

Author

Oubaya, Nadia, primary, Pombet, Thibaud, additional, Delestrain, Celine, additional, Remus, Natascha, additional, Douvry, Benoit, additional, Grenet, Dominique, additional, Corvol, Harriet, additional, Thouvenin, Guillaume, additional, Prulière-Escabasse, Virginie, additional, Mounir, Hakima, additional, Argoud, Dominique, additional, Fretigne, Cédric, additional, Costes, Laurence, additional, Mackiewicz, Marie-Pierre, additional, Jung, Camille, additional, Ahamada, Laitissia, additional, Lanone, Sophie, additional, Maitre, Bernard, additional, Bégot, Anne-Cécile, additional, and Epaud, Ralph, additional

Published
2022
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25. Acute respiratory distress syndrome mimickers lacking common risk factors of the Berlin definition

Author

Gibelin, Aude, Parrot, Antoine, Maitre, Bernard, Brun-Buisson, Christian, Mekontso Dessap, Armand, Fartoukh, Muriel, and de Prost, Nicolas

Subjects
Medical research, Medicine, Experimental, Respiratory distress syndrome -- Risk factors, Mortality -- France -- United Kingdom -- Germany, Acute respiratory distress syndrome -- Risk factors, Health care industry
Abstract

Purpose Some patients presenting with acute respiratory failure and meeting the Berlin criteria for acute respiratory distress syndrome (ARDS) lack exposure to common risk factors (CRF). These so-called ARDS mimickers often lack histological diffuse alveolar damage. We aimed to describe such ARDS mimickers lacking CRF (ARDS.sub.CRF-) in comparison with others (ARDS.sub.CRF+). Methods Retrospective study including all patients receiving invasive mechanical ventilation for ARDS admitted to the intensive care units (ICUs) of two tertiary care centers from January 2003 to December 2012. Results The prevalence of ARDS.sub.CRF- was 7.5 % (95 % CI [5.5-9.5]; n = 50/665). On the basis of medical history, bronchoalveolar lavage fluid cytology, and chest CT scan patterns, four etiological categories were identified: immune (n = 18; 36 %), drug-induced (n = 13; 26 %), malignant (n = 7; 14 %), and idiopathic (n = 12; 24 %). Although the ARDS.sub.CRF- patients had a lower logistic organ dysfunction score (4 [3-8] vs. 10 [6-13]; p < 0.0001) and less often shock upon ICU admission (44 vs. 80 %; p < 0.0001) than their counterparts, their overall ICU mortality rate was very high (66 % [46-74]), and the absence of CRF remained associated with ICU mortality by multivariable logistic regression analysis (adjusted OR = 2.06; 95 % CI [1.02-4.18]; p = 0.044). Among ARDS.sub.CRF- patients, the presence of potentially reversible lung lesions with corticosteroids (aOR = 0.14; 95 % CI [0.03-0.62]) was associated with ICU survival. Conclusions The absence of CRF among patients with ARDS is common and associated with a higher risk of mortality. For such atypical ARDS, a complete diagnostic workup, including bronchoalveolar lavage fluid cytology and chest CT scan patterns, should be performed to identify those patients who might benefit from specific therapies, including corticosteroids., Author(s): Aude Gibelin [sup.1] [sup.2], Antoine Parrot [sup.1] [sup.2], Bernard Maitre [sup.3], Christian Brun-Buisson [sup.4] [sup.5], Armand Mekontso Dessap [sup.4] [sup.5], Muriel Fartoukh [sup.1] [sup.2] [sup.5], Nicolas de Prost [sup.4] [...]

Published
2016
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26. Otological Manifestations in Adults with Primary Ciliary Dyskinesia: A Controlled Radio-Clinical Study

Author

Alexandru, Mihaela, primary, de Boissieu, Paul, additional, Benoudiba, Farida, additional, Moustarhfir, Malik, additional, Kim, Sookyung, additional, Bequignon, Émilie, additional, Honoré, Isabelle, additional, Garcia, Gilles, additional, Mitri-Frangieh, Rana, additional, Legendre, Marie, additional, Crestani, Bruno, additional, Taillé, Camille, additional, Escudier, Estelle, additional, Maitre, Bernard, additional, Papon, Jean-François, additional, and Nevoux, Jérôme, additional

Published
2022
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28. The disease-specific clinical trial network for primary ciliary dyskinesia: PCD-CTN

Author

Raidt, Johanna, primary, Maitre, Bernard, additional, Pennekamp, Petra, additional, Altenburg, Josje, additional, Anagnostopoulou, Pinelopi, additional, Armengot, Miguel, additional, Bloemsma, Lizan D., additional, Boon, Mieke, additional, Borrelli, Melissa, additional, Brinkmann, Folke, additional, Carr, Siobhan B., additional, Carroll, Mary P., additional, Castillo-Corullón, Silvia, additional, Coste, André, additional, Cutrera, Renato, additional, Dehlink, Eleonora, additional, Destouches, Damien M.S., additional, Di Cicco, Maria E., additional, Dixon, Lucy, additional, Emiralioglu, Nagehan, additional, Erdem Eralp, Ela, additional, Haarman, Eric G., additional, Hogg, Claire, additional, Karadag, Bulent, additional, Kobbernagel, Helene E., additional, Lorent, Natalie, additional, Mall, Marcus A., additional, Marthin, June K., additional, Martinu, Vendula, additional, Narayanan, Manjith, additional, Ozcelik, Ugur, additional, Peckham, Daniel, additional, Pifferi, Massimo, additional, Pohunek, Petr, additional, Polverino, Eva, additional, Range, Simon, additional, Ringshausen, Felix C., additional, Robson, Evie, additional, Roehmel, Jobst, additional, Rovira-Amigo, Sandra, additional, Santamaria, Francesca, additional, Schlegtendal, Anne, additional, Szépfalusi, Zsolt, additional, Tempels, Petra, additional, Thouvenin, Guillaume, additional, Ullmann, Nicola, additional, Walker, Woolf T., additional, Wetzke, Martin, additional, Yiallouros, Panayiotis, additional, Omran, Heymut, additional, and Nielsen, Kim G., additional

Published
2022
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29. The disease-specific clinical trial network for primary ciliary dyskinesia:PCD-CTN

Author

Raidt, Johanna, Maitre, Bernard, Pennekamp, Petra, Altenburg, Josje, Anagnostopoulou, Pinelopi, Armengot, Miguel, Bloemsma, Lizan D., Boon, Mieke, Borrelli, Melissa, Brinkmann, Folke, Carr, Siobhan B., Carroll, Mary P., Castillo-Corullón, Silvia, Coste, André, Cutrera, Renato, Dehlink, Eleonora, Destouches, Damien M.S., Di Cicco, Maria E., Dixon, Lucy, Emiralioglu, Nagehan, Eralp, Ela Erdem, Haarman, Eric G., Hogg, Claire, Karadag, Bulent, Kobbernagel, Helene E., Lorent, Natalie, Mall, Marcus A., Marthin, June K., Martinu, Vendula, Narayanan, Manjith, Ozcelik, Ugur, Peckham, Daniel, Pifferi, Massimo, Pohunek, Petr, Polverino, Eva, Range, Simon, Ringshausen, Felix C., Robson, Evie, Roehmel, Jobst, Rovira-Amigo, Sandra, Santamaria, Francesca, Schlegtendal, Anne, Szépfalusi, Zsolt, Tempels, Petra, Thouvenin, Guillaume, Ullmann, Nicola, Walker, Woolf T., Wetzke, Martin, Yiallouros, Panayiotis, Omran, Heymut, Nielsen, Kim G., Raidt, Johanna, Maitre, Bernard, Pennekamp, Petra, Altenburg, Josje, Anagnostopoulou, Pinelopi, Armengot, Miguel, Bloemsma, Lizan D., Boon, Mieke, Borrelli, Melissa, Brinkmann, Folke, Carr, Siobhan B., Carroll, Mary P., Castillo-Corullón, Silvia, Coste, André, Cutrera, Renato, Dehlink, Eleonora, Destouches, Damien M.S., Di Cicco, Maria E., Dixon, Lucy, Emiralioglu, Nagehan, Eralp, Ela Erdem, Haarman, Eric G., Hogg, Claire, Karadag, Bulent, Kobbernagel, Helene E., Lorent, Natalie, Mall, Marcus A., Marthin, June K., Martinu, Vendula, Narayanan, Manjith, Ozcelik, Ugur, Peckham, Daniel, Pifferi, Massimo, Pohunek, Petr, Polverino, Eva, Range, Simon, Ringshausen, Felix C., Robson, Evie, Roehmel, Jobst, Rovira-Amigo, Sandra, Santamaria, Francesca, Schlegtendal, Anne, Szépfalusi, Zsolt, Tempels, Petra, Thouvenin, Guillaume, Ullmann, Nicola, Walker, Woolf T., Wetzke, Martin, Yiallouros, Panayiotis, Omran, Heymut, and Nielsen, Kim G.

Abstract

Primary ciliary dyskinesia (PCD) is a rare genetic disorder characterised by impaired mucociliary clearance leading to irreversible lung damage. In contrast to other rare lung diseases like cystic fibrosis (CF), there are only few clinical trials and limited evidence-based treatments. Management is mainly based on expert opinions and treatment is challenging due to a wide range of clinical manifestations and disease severity. To improve clinical and translational research and facilitate development of new treatments, the clinical trial network for PCD (PCD-CTN) was founded in 2020 under the framework of the European Reference Network (ERN)-LUNG PCD Core. Applications from European PCD sites interested in participating in the PCD-CTN were requested. Inclusion criteria consisted of patient numbers, membership of ERN-LUNG PCD Core, use of associated standards of care, experience in PCD and/or CF clinical research, resources to run clinical trials, good clinical practice (GCP) certifications and institutional support. So far, applications from 22 trial sites in 18 European countries have been approved, including >1400 adult and >1600 paediatric individuals with PCD. The PCD-CTN is headed by a coordinating centre and consists of a steering and executive committee, a data safety monitoring board and committees for protocol review, training and standardisation. A strong association with patient organisations and industrial companies are further cornerstones. All participating trial sites agreed on a code of conduct. As CTNs from other diseases have demonstrated successfully, this newly formed PCD-CTN operates to establish evidence-based treatments for this orphan disease and to bring new personalised treatment approaches to patients.

Published
2022

33. TTC12 loss-of-function mutations cause primary ciliary dyskinesia and unveil distinct dynein assemblymechanisms in motile cilia versus flagella

Author

THOMAS, Lucie, Bouhouche, Khaled, Whitfield, Marjorie, Thouvenin, Guillaume, Coste, André, Louis, Bruno, Szymanski, Claire, Bequignon, Emilie, Papon, Jean-François, Castelli, Manon, Lemullois, Michel, Dhalluin, Xavier, Drouin-Garraud, Valérie, Montantin, Guy, Tissier, Sylvie, Duquesnoy, Philippe, Copin, Bruno, Dastot - Le Moal, Florence, Couvet, Sandrine, Barbotin, Anne Laure, Faucon, Catherine, Honoré, Isabelle, Maitre, Bernard, Beydon, Nicole, Tamalet, Aline, Rives, Nathalie, Koll, France, Escudier, Estelle, Tassin, Anne-Marie, Touré, Aminata, Mitchell, Valerie, Amselem, Serge, Legendre, Marie, Couvet, Sandrine, Maladies génétiques d'expression pédiatrique (U933), Institut National de la Santé et de la Recherche Médicale (INSERM)-CHU Trousseau [APHP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU), Gif-sur-Yvette, Institute for Advanced Biosciences / Institut pour l'Avancée des Biosciences (Grenoble) (IAB), Centre Hospitalier Universitaire [Grenoble] (CHU)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Etablissement français du sang - Auvergne-Rhône-Alpes (EFS)-Centre National de la Recherche Scientifique (CNRS)-Université Grenoble Alpes (UGA), Hôpital Trousseau, Centre Hospitalier Régional Universitaire de Tours (CHRU Tours), Hôpital Henri Mondor, Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Hôpital Henri Mondor-Université Paris-Est Créteil Val-de-Marne - Paris 12 (UPEC UP12), Centre Hospitalier Intercommunal de Créteil (CHIC), IMRB - 'Biomechanics and Respiratory Apparatus' [Créteil] (U955 Inserm - UPEC), Institut Mondor de Recherche Biomédicale (IMRB), Institut National de la Santé et de la Recherche Médicale (INSERM)-IFR10-Université Paris-Est Créteil Val-de-Marne - Paris 12 (UPEC UP12)-Institut National de la Santé et de la Recherche Médicale (INSERM)-IFR10-Université Paris-Est Créteil Val-de-Marne - Paris 12 (UPEC UP12), Service d'ORL et de Chirurgie Cervico-Faciale (LILLE - ORL et CCF), Centre Hospitalier Régional Universitaire [Lille] (CHRU Lille), Service d’ORL et de chirurgie cervico-faciale [CHU Le Kremlin-Bicêtre], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-AP-HP Hôpital Bicêtre (Le Kremlin-Bicêtre), Clinique de pneumologie [CHRU Lille], Service de génétique [Rouen], CHU Rouen, Normandie Université (NU)-Normandie Université (NU)-Université de Rouen Normandie (UNIROUEN), Normandie Université (NU), CHU Trousseau [APHP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU), Department of Reproductive Biology and Spermiology-CECOS Lille, University Medical Center, Lille, 59037, France., Université de Lille-Centre Hospitalier Régional Universitaire [Lille] (CHRU Lille), Service de pneumologie [CHU Cochin], Hôpital Cochin [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Maladies génétiques d'expression pédiatrique [CHU Trousseau] (Inserm U933), and UF de Génétique moléculaire [CHU Trousseau]

Subjects
dynein arm assembly, [SDV] Life Sciences [q-bio], [SDV.GEN.GH]Life Sciences [q-bio]/Genetics/Human genetics, [SDV]Life Sciences [q-bio], cilia, primary ciliary dyskinesia, CRISPR-Cas9, [SDV.GEN.GH] Life Sciences [q-bio]/Genetics/Human genetics, TTC12, sperm flagella
Abstract

International audience; Cilia and flagella are evolutionarily conserved organelles whose motility relies on the outer and inner dynein arm complexes (ODAs/IDAs). Defects in ODAs/IDAs result in primary ciliary dyskinesia (PCD), a disease characterized by recurrent airway infections and male infertility. To date PCD mutations in assembly factors cause a combined ODA/IDA defect, affecting both cilia and flagella. We identified four loss-of-function mutations in TTC12, which encodes a cytoplasmic protein, in four independent families in which affected individuals displayed a peculiar PCD phenotype characterized by the absence of ODAs and IDAs in sperm flagella, contrasting with the sole absence of IDAs in respiratory cilia. We analysed both primary cells from individuals carrying TTC12 mutations and human differentiated airway cells invalidated for TTC12 by a CRISPR-Cas9 approach, as well as TTC12 depletion in the ciliated model, Paramecium tetraureli. Our results revealed an IDA defect restricted to a subset of single-headed IDAs different in flagella and cilia, while TTC12 depletion in Paramecium tetraurelia recapitulated the sperm phenotype. Overall, our study, which identifies TTC12 as a new gene involved in PCD, unveils distinct dynein assembly mechanisms in human motile cilia versus flagella.

Published
2022

35. Functional Ex Vivo Testing of Alveolar Monocytes in Patients with Pneumonia-Related ARDS

Author

Bendib, Inès, primary, Beldi-Ferchiou, Asma, additional, Schlemmer, Frédéric, additional, Maitre, Bernard, additional, Surenaud, Mathieu, additional, Hüe, Sophie, additional, Carteaux, Guillaume, additional, Razazi, Keyvan, additional, Lelièvre, Jean-Daniel, additional, Lévy, Yves, additional, Mekontso Dessap, Armand, additional, Godot, Véronique, additional, and de Prost, Nicolas, additional

Published
2021
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40. Impact of a rare respiratory diseases reference centre set-up on primary ciliary dyskinesia care pathway

Author

Epaud, Salome, primary, Epaud, Ralph, additional, Salaün-Penquer, Noemie, additional, Belozertseva, Ekatarina, additional, Remus, Natascha, additional, Douvry, Benoit, additional, Bequignon, Emilie, additional, Coste, Andre, additional, Prulière-Escabasse, Virginie, additional, Schlemmer, Frédéric, additional, Jung, Camille, additional, Ortala, Matthieu, additional, Maitre, Bernard, additional, and Delestrain, Céline, additional

Published
2021
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41. International French-speaking multicentre practice survey on hepatic hydrothorax (HH) : Results of the "Hep Hep" study among 529 hepatogastroenterologist (HG) or pneumologist (PN) respondents

Author

Cadranel, Jean-François, primary, Jacques, Cadranel, additional, Ollivier, Isabelle, additional, Thevenot, Thierry, additional, Nguyen-Khac, Eric, additional, Bureau, Christophe, additional, Allaire, Manon, additional, Nousbaum, Jean-Baptiste, additional, Loustaud-Ratti, Véronique, additional, Causse, Xavier, additional, Sogni, Philippe, additional, Hanslik, Bertrand, additional, Bourlière, Marc, additional, Péron, Jean-Marie, additional, Ganne-Carrié, Nathalie, additional, Dao, Thong, additional, Maitre, Bernard, additional, Elkrief, Laure, additional, Raherison, Chantal, additional, and Le Magoarou, Tristan, additional

Published
2021
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42. International BEAT-PCD Consensus Statement for infection prevention and control in Primary Ciliary Dyskinesia in collaboration with ERN-LUNG PCD Core Network and patient representatives

Author

Marthin, June Kehlet, primary, Lucas, Jane, additional, Boon, Mieke, additional, Crowley, Suzanne, additional, Casualta, Carmen, additional, Destouches, Damien Ms, additional, Eber, Ernst, additional, Escribano, Amparo, additional, Haarman, Eric, additional, Hogg, Claire, additional, Maitre, Bernard, additional, Marsh, Gemma, additional, Martinu, Vendula, additional, Moreno-Galdó, Antonio, additional, Mussaffi, Huda, additional, Omran, Heymut, additional, Pohunek, Petr, additional, Rindlisbacher, Bernhard, additional, Robinson, Phil, additional, Snijders, Deborah, additional, Yiallouros, Panayiotis, additional, Walker, Wolf, additional, Johansen, Helle Krogh, additional, and Nielsen, Kim G, additional

Published
2021
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43. Development and first results of the BEAT-PCD international Primary Ciliary Dyskinesia gene variant database: CiliaVar

Author

Mani, Rahma, primary, Gomes, Mafalda, additional, González, Adrián Rodríguez, additional, Hogg, Claire, additional, Morris-Rosendahl, Deborah, additional, Maitre, Bernard, additional, Fassad, Mahmoud R, additional, Goutaki, Myrofora, additional, Lucas, Jane S, additional, Shoemark, Amelia, additional, Mitchison, Hannah M, additional, Legendre, Marie, additional, and Crowley, Suzanne, additional

Published
2021
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46. Air pollution as an early determinant of COPD.

Author

Zhuyi Lu, Coll, Patrice, Maitre, Bernard, Epaud, Ralph, and Lanone, Sophie

Subjects
AIR pollution, OBSTRUCTIVE lung diseases, RESPIRATORY diseases, AIR pollutants, BRONCHITIS
Abstract

COPD is a progressive and debilitating disease often diagnosed after 50 years of age, but more recent evidence suggests that its onset could originate very early on in life. In this context, exposure to air pollution appears to be a potential contributor. Although the potential role of air pollution as an early determinant of COPD is emerging, knowledge gaps still remain, including an accurate qualification of air pollutants (number of pollutants quantified and exact composition) or the "one exposure-one disease" concept, which might limit the current understanding. To fill these gaps, improvements in the field are needed, such as the use of atmosphere simulation chambers able to realistically reproduce the complexity of air pollution, consideration of the exposome, as well as improving exchanges between paediatricians and adult lung specialists to take advantage of reciprocal expertise. This review should lead to a better understanding of the current knowledge on air pollution as an early determinant of COPD, as well as identify the existing knowledge gaps and opportunities to fill them. Hopefully, this will lead to better prevention strategies to scale down the development of COPD in future generations. [ABSTRACT FROM AUTHOR]

Published
2022
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48. Etiological Work-Up for Adults with Bronchiectasis: A Predictive Diagnostic Score for Primary Ciliary Dyskinesia and Cystic Fibrosis

Author

Schlemmer, Frederic, primary, Hamzaoui, Agnes, additional, Zebachi, Sonia, additional, Le Thuaut, Aurelie, additional, Mangiapan, Gilles, additional, Monnet, Isabelle, additional, Boudjema, Amel, additional, Jabot, Laurence, additional, Housset, Bruno, additional, Bastuji-Garin, Sylvie, additional, Bassinet, Laurence, additional, and Maitre, Bernard, additional

Published
2021
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49. Cardiovascular phenotypes predict clinical outcomes in sickle cell disease: An echocardiography‐based cluster analysis

Author

d'Humières, Thomas, primary, Savale, Laurent, additional, Inamo, Jocelyn, additional, Deux, Jean‐François, additional, Deswarte, Simon, additional, Lionnet, Francois, additional, Loko, Gylna, additional, Chantalat, Christelle, additional, Damy, Thibaud, additional, Guillet, Henri, additional, Pham Hung d'Alexandry d'Orengiani, Anne Laure, additional, Galactéros, Frédéric, additional, Audureau, Etienne, additional, Maitre, Bernard, additional, Humbert, Marc, additional, Derumeaux, Geneviève, additional, and Bartolucci, Pablo, additional

Published
2021
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50. Rapid Improvement after Starting Elexacaftor–Tezacaftor–Ivacaftor in Patients with Cystic Fibrosis and Advanced Pulmonary Disease

Author

Burgel, Pierre-Régis, primary, Durieu, Isabelle, additional, Chiron, Raphaël, additional, Ramel, Sophie, additional, Danner-Boucher, Isabelle, additional, Prevotat, Anne, additional, Grenet, Dominique, additional, Marguet, Christophe, additional, Reynaud-Gaubert, Martine, additional, Macey, Julie, additional, Mely, Laurent, additional, Fanton, Annlyse, additional, Quetant, Sébastien, additional, Lemonnier, Lydie, additional, Paillasseur, Jean-Louis, additional, Da Silva, Jennifer, additional, Martin, Clémence, additional, Andrejak, Claire, additional, Becourt, Arnaud, additional, Mounard, Julie, additional, Poulet, Claire, additional, Rames, Cinthia, additional, Talleux, Marie, additional, Chevalier, Marie-Chantal, additional, Darviot, Estelle, additional, Jouvenot, Marie, additional, Marien, Caroline, additional, Paris, Audrey, additional, Pelatan, Cécile, additional, Person, Christine, additional, Priou, Pascaline, additional, Troussier, Françoise, additional, Urban, Thierry, additional, Dalphin, Marie-Laure, additional, Dalphin, Jean-Charles, additional, Ladaurade, Alice, additional, Pernet, Didier, additional, Richaud-Thiriez, Bénédicte, additional, Roux-Claude, Pauline, additional, Blanc, Nathalia, additional, Boisserie-Lacroix, Vincent, additional, Bui, Stephanie, additional, Collet, Cyrielle, additional, Debelleix, Stéphane, additional, Bergot, Emmanuel, additional, Brouard, Jacques, additional, Campbell, Karine, additional, Laurans, Muriel, additional, Ribault, Virginie, additional, Borderon, Corinne, additional, Heraud, Marie-Christine, additional, Labbe, Guillaume, additional, Montcouquiol, Sylvie, additional, Petit, Isabelle, additional, Ruivard, Marc, additional, Delestrain, Céline, additional, Douvry, Benoit, additional, Epaud, Ralph, additional, Maitre, Bernard, additional, Remus, Natascha, additional, Beltramo, Guillaume, additional, Houzel, Anne, additional, Huet, Frédéric, additional, Perez, Stéphanie, additional, Boldron-Ghaddar, Amale, additional, Scalbert, Manuela, additional, Bouzioukh, Rabah, additional, Simon, Charles, additional, Camara, Boubou, additional, Hamidfar, Rébecca, additional, Llerena, Catherine, additional, Pin, Isabelle, additional, Deschildre, Antoine, additional, Gicquello, Alice, additional, Le Rouzic, Olivier, additional, Leroy, Clara, additional, Paris, Nicolas, additional, Perez, Thierry, additional, Thumerelle, Caroline, additional, Turck, Dominique, additional, Wizla, Nathalie, additional, Dupuy-Grasset, Magali, additional, Languepin, Jane, additional, Masson-Rouchaud, Alexandra, additional, Menetrey, Céline, additional, Durupt, Stéphane, additional, L’Excellent, Sophie, additional, Nove-Josserand, Raphaele, additional, Ohlmann, Camille, additional, Reix, Phillipe, additional, Reynaud, Quitterie, additional, Werck-Gallois, Marie-Christine, additional, Baravalle, Mélissandre, additional, Coltey, Bérangère, additional, Desmazes-Dufeu, Nadine, additional, Dubus, Jean-Christophe, additional, Gautier, Clarisse, additional, Rey, Jean-Baptiste, additional, Stremler, Nathalie, additional, Caimmi, Davide, additional, Devrait, Margot, additional, Moreau, Johan, additional, Billon, Yves, additional, Blondé, Aurore, additional, Guillaumot, Anne, additional, Kiefer, Sébastien, additional, Peretti, Laura, additional, Tatopoulos, Aurélie, additional, Tiotiu, Angélica, additional, Benhamida, Myriam, additional, Bihouee, Tiphaine, additional, Eschapasse, Emmanuel, additional, Tissot, Adrien, additional, Giannantonio, Marie, additional, Leroy, Sylvie, additional, Piccini-Bailly, Carole, additional, Pradelli, Johana, additional, Messika, Jonathan, additional, Boussaud, Véronique, additional, Burgel, Pierre-Régis, additional, Carlier, Nicolas, additional, Honoré, Isabelle, additional, Hubert, Dominique, additional, Kanaan, Reem, additional, Bailly-Botuha, Céline, additional, Chedevergne, Frédérique, additional, De Blic, Jacques, additional, Delacourt, Christophe, additional, Drummond, David, additional, Fauroux, Brigitte, additional, Karila, Chantal, additional, Le Bourgeois, Muriel, additional, Sermet, Isabelle, additional, Delaisi, Bertrand, additional, Gerardin, Michèle, additional, Houdouin, Veronique, additional, Leclainche, Laurence, additional, Aubertin, Guillaume, additional, Berdah, Laura, additional, Clement, Annick, additional, Corvol, Harriet, additional, Nathan, Nadia, additional, Prevost, Blandine, additional, Richard, Nicolas, additional, Tamalet, Aline, additional, Taytard, Jessica, additional, Thouvenin, Guillaume, additional, Tourniaire, Barbara, additional, Abely, Michel, additional, Bessaci-Kabouya, Katia, additional, Dury, Sandra, additional, Ravoninjatovo, Bruno, additional, Dabadie, Alain, additional, Dagorne, Michel, additional, Deneuville, Eric, additional, Jamin, Marie, additional, Ribault, Mélanie, additional, Vigier, Clémentine, additional, Belleguic, Chantal, additional, Brinchault, Graziella, additional, Desrues, Benoit, additional, Barzic, Audrey, additional, Dirou-Prigent, Anne, additional, Le Bihan, Jean, additional, Revert, Krista, additional, Ropars, Thomas, additional, Couderc, Laure, additional, Dominique, Stéphane, additional, Morisse-Pradier, Hélène, additional, Pramil, Stéphanie, additional, Thiberville, Luc, additional, Allou, Nathalie, additional, Enaud, Laurent, additional, Gachelin, Elsa, additional, Huchot, Eric, additional, Payet, Annabelle, additional, Perisson, Caroline, additional, Piyaraly, Saguiraly, additional, Valois, Sophie, additional, Herzog, Audrey, additional, Kessler, Romain, additional, Porzio, Michele, additional, Weiss, Laurence, additional, Beaumont, Laurence, additional, Brugiere, Olivier, additional, Colin, Sylvie, additional, Verdiere, de, additional, Cuquemelle, Elise, additional, De Miranda, Sandra, additional, Monem Hamid, Adbdul, additional, Parquin, François, additional, Picard, Clément, additional, Roux, Antoine, additional, Roy, Charlotte, additional, Bremont, François, additional, Didier, Alain, additional, Dupuis, Marion, additional, Faviez, Guillaume, additional, Labouret, Géraldine, additional, Mittaine, Marie, additional, Murris-Espin, Marlène, additional, Roditis, Léa, additional, Cosson, Laure, additional, Diot, Patrice, additional, Flament, Thomas, additional, Giraut, Charlotte, additional, Mankikian, Julie, additional, Arnouat, Baptiste, additional, Mousset, Gaétane, additional, Storni, Véronique, additional, Vigneron, Philippe, additional, Coirier-Duet, Emmanuelle, additional, and Gabsi, Asma, additional

Published
2021
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