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A prospective study on 193 patients through 3 years from February 2020 till January 2023 patients complain of colorectal carcinoma in different locations. 43 patients (23%) had a history of open or laparoscopic cholecystectomy since a different time ranging from 9 to more than 30 years, who have no family history of colorectal cancer or inflammatory bowel diseases, adenomatous polyps, and no history of familial adenomatous polyposis, (predisposing factors of colorectal cancer). most common location of malignancy for those patients with a history of cholecystectomy in the RT side of the colon 21 patients (48.8%) and the least location in the ano-rectum region one patient (2.4%). The most common time that we diagnosed colorectal carcinoma after 21 to 25 years from the time of cholecystectomy which occurred in 18 patients (41.9%) and the least after 9 years only one patient (2.4). While the microscopic appearance of colorectal cancer in patients with a history of cholecystectomy is, adenocarcinoma occurs in 38 patients (88.4%) and squamous carcinoma occurs in 5 patients (11.6%). While the macroscopic appearance of colorectal cancer occurs most commonly in ulcerative types in 29 patients (67.5%) and least annular type 5 patients (11.6%) and the most common age occur between the age of 60 and 69 years in 24 patients (55.8%) and leas occur at the age of 40 to 49 years only 2 patients (4.6%), about the grading of the tumor moderate differentiated type, is the most common type in 67.5% Aim of the study to know the incidence of colorectal carcinoma after cholecystectomy, locations of tumors, and related time. [ABSTRACT FROM AUTHOR]