Search

Your search keyword '"Malhotra, Indu"' showing total 180 results
Start Over Author "Malhotra, Indu"
180 results on '"Malhotra, Indu"'

1. Prevalence of and risk factors for microscopic and submicroscopic malaria infections in pregnancy: a systematic review and meta-analysis

Author

van Eijk, Anna Maria, Stepniewska, Kasia, Hill, Jenny, Taylor, Steve M., Rogerson, Stephen J., Cottrell, Gilles, Chico, R. Matthew, Gutman, Julie R., Tinto, Hallidou, Unger, Holger W., Yanow, Stephanie K., Accrombessi, Manfred, Adegnika, Ayola A., Ahmed, Rukhsana, Arango-Flórez, Eliana María, Arevalo-Herrera, Myriam, Arinaitwe, Emmanual, Arnaldo, Paulo, Ashorn, Per, Ashorn, Ulla, Bardaji, Azucena, Betuela, Inoni, Bharti, Praveen K., Bohissou, Francis, Bôtto-Menezes, Camila, Braun, Vera, Briand, Valerie, Briggs, Jessica, Castellanos, María Eugenia, Chandramohan, Daniel, Chaponda, Enesia Banda, Chitnis, Chetan, Cohee, Lauren M., Cot, Michel, d'Alessandro, Umberto, Denoeud-Ndam, Lise, Desai, Meghna, Dicko, Alassane, Ding, Xavier, Dorsey, Grant, Duffy, Patrick E., Elbadry, Maha A., Enosse, Sonia M., Fan, Yue, Fievet, Nadine, Fried, Michal, Genton, Blaise, Gonzalez, Raquel, Greenwood, Brian, Kalilani, Linda, Kattenberg, Johanna H., Kayentao, Kassoum, Khairallah, Carole, King, Christopher L., Kochar, Dhanpat Kumar, Kochar, Swati, Koukouikila-Koussounda, Felix, Landis, Sarah H., Laufer, Miriam K., Leke, Rose F., Macete, Eusebio, Maculuve, Sonia, Madanitsa, Mwayiwawo, Mahamar, Almahamoudou, Maleta, Ken, Malhotra, Indu, Zoleko Manego, Rella, Martinez-Espinosa, Flor Ernestina, Massougbodji, Achille, Mathanga, Don, Menegon, Michela, Menendez, Clara, Mens, Petra, Meremikwu, Martin, Mockenhaupt, Frank P., Mombo-Ngoma, Ghyslain, Mosha, Dominic, Mueller, Ivo, Nahum, Alain, Natureeba, Paul, Ndam, Nicaise, Ntoumi, Francine, Oduwole, Olabisi A., Okech, Bernard A., Ome-Kaius, Maria, Otieno, Kephas, Padilla, Norma, Ramharter, Michal, Rochford, Rosemary, Rosanas-Urgell, Anna, Ruperez, Maria, Sabourin, Katherine R., Sanz, Sergi, Schallig, Henk D., Scott, Susana, Sevene, Esperanca, Severini, Carlo, Tagbor, Harry, Taylor, Diane Wallace, Traore Coulibaly, Maminata, Vasquez, Ana, Walker-Abbey, Annie, Wylie, Blair J., Zannou, Djimon M., Meshnick, Stephen R., ter Kuile, Feiko O., Mayor, Alfredo, Taylor, Steve M, Rogerson, Stephen J, Chico, R Matthew, Gutman, Julie R, Tinto, Halidou, Unger, Holger W, Yanow, Stephanie K, Meshnick, Steven R, and ter Kuile, Feiko O

Published
2023
Full Text
View/download PDF

6. Acquired Clinical Immunity to Malaria in Nonhuman Primates Coinfected with Schistosoma and Plasmodium Parasites

Author

Nyakundi, Ruth K., primary, Hau, Jann, additional, Ogongo, Paul, additional, Nyamongo, Onkoba, additional, Jeneby, Maamum, additional, Akinyi, Mercy, additional, Mulei, Isaac, additional, Nyundo, Fred, additional, Farah, Idle, additional, Malhotra, Indu, additional, Ozwara, Hastings, additional, King, Christopher L., additional, and Kariuki, Thomas, additional

Published
2022
Full Text
View/download PDF

12. Early Childhood Anemia in a Birth Cohort in Coastal Kenya: Links to Infection and Nutrition

Author

Kao, Julia, Mutuku, Francis, Martin, Shanique, Lee, Justin, Mwandi, Jackson, Mukoko, Dunstan, Malhotra, Indu, King, Charles H., and LaBeaud, Angelle Desiree

Subjects
Male, Helminthiasis, Infant, Nutritional Status, Anemia, Articles, Child Nutrition Disorders, Kenya, Malaria, Cohort Studies, Cross-Sectional Studies, Socioeconomic Factors, Child, Preschool, Prevalence, Humans, Female
Abstract

Anemia is known to impact a child’s growth and development, but not all anemias are caused by iron deficiency, and the CDC and WHO have emphasized investigating other contributors to anemia. This cross-sectional sub-study of a 2012–2016 maternal-child cohort in coastal Kenya evaluated 244 children and found 185 (76%) to have been anemic on at least one time point since birth. At the time of assessment in 2016, evaluation included a complete blood count, nutritional assessment, and testing for parasitic infections, focusing on the primary outcome of anemia, defined as hemoglobin (Hb) < 11 g/dL. The average age at assessment was 20.5 ± 7 months. Ninety-five percent had a lifetime average Hb in the anemic range. Adjusting for age and gender, prior or current malaria infection (prior: Hb β = −0.99, 95% CI: −1.49 to −0.49, P = 0.01), or having any current infection with hookworm, Trichuris, Strongyloides, Ascaris, and/or malaria (β = −0.84, 95% CI: −1.36 to −0.33, P = 0.01) was associated with decreased current Hb. Nutritional evaluation revealed that children with a declining Hb ate fewer vitamin-A–rich vegetables per week (P = 0.01) or eggs (P = 0.01), drank more milk (P = 0.07), and ate more bread (P = 0.01), and were more likely to live in a household that experienced food shortage (P = 0.05). The high prevalence of anemia, polyparasitism, and dietary insufficiency among children in rural coastal Kenya suggests that remedial interventions will need to address both diet and parasitic infections to effectively combat this significant health threat.

Published
2019

13. Additional file 2 of Factors associated with early childhood stunted growth in a 2012–2015 birth cohort monitored in the rural Msambweni area of coastal Kenya: a cross-sectional study

Author

Martin, Shanique, Mutuku, Francis, Sessions, Julia, Lee, Justin, Dunstan Mukoko, Malhotra, Indu, King, Charles H., and A. Desiree LaBeaud

Abstract

Additional File 2. Standardized mean difference of HAZ at 6-month intervals, by stunting status, for all study participants and for the subset of 77 study participants with complete anthropometric data from 6 to 24 months of age.

Published
2020
Full Text
View/download PDF

14. Additional file 1 of Factors associated with early childhood stunted growth in a 2012–2015 birth cohort monitored in the rural Msambweni area of coastal Kenya: a cross-sectional study

Author

Martin, Shanique, Mutuku, Francis, Sessions, Julia, Lee, Justin, Dunstan Mukoko, Malhotra, Indu, King, Charles H., and A. Desiree LaBeaud

Abstract

Additional File 1. Socioeconomic Status Survey. The 84-question socioeconomic status and family planning survey used to determine SES using WAMI index and PCA asset score. Adapted from Psaki et al.

Published
2020
Full Text
View/download PDF

15. Iron Deficiency Anemia at Time of Vaccination Predicts Decreased Vaccine Response and Iron Supplementation at Time of Vaccination Increases Humoral Vaccine Response: A Birth Cohort Study and a Randomized Trial Follow-Up Study in Kenyan Infants

Author

Stoffel, Nicole U., primary, Uyoga, Mary A., additional, Mutuku, Francis M., additional, Frost, Joe N., additional, Mwasi, Edith, additional, Paganini, Daniela, additional, van der Klis, Fiona R. M., additional, Malhotra, Indu J., additional, LaBeaud, A. Desiráe, additional, Ricci, Cristian, additional, Karanja, Simon, additional, Drakesmith, Hal, additional, King, Charles H., additional, and Zimmermann, Michael B., additional

Published
2020
Full Text
View/download PDF

16. Prevalence of PfDHFR and PfDHPS Mutations Associated with Drug Resistance Among Pregnant Women Receiving IPTp-SP at Msambweni County Referral Hospital, Kwale County, Kenya

Author

Gikunju, Stella Wanjiku, primary, Agola, Eric L., additional, Ondondo, Raphael Omusebe, additional, Kinyua, Johnson Kangethe, additional, Kimani, Francis, additional, LaBeaud, Angelle Desiree, additional, Malhotra, Indu, additional, King, Charles H., additional, Thiong’o, Kelvin, additional, and Mutuku, Francis, additional

Published
2019
Full Text
View/download PDF

20. Parasitic infections during pregnancy need not affect infant antibody responses to early vaccination against Streptococcus pneumoniae, diphtheria, or Haemophilus influenzae type B

Author

McKittrick, Noah D., primary, Malhotra, Indu J., additional, Vu, David M., additional, Boothroyd, Derek B., additional, Lee, Justin, additional, Krystosik, Amy R., additional, Mutuku, Francis M., additional, King, Charles H., additional, and LaBeaud, A. Desirée, additional

Published
2019
Full Text
View/download PDF

23. Identification of highly-protective combinations of Plasmodium vivax recombinant proteins for vaccine development

Author

França, Camila Tenorio, primary, White, Michael T, additional, He, Wen-Qiang, additional, Hostetler, Jessica B, additional, Brewster, Jessica, additional, Frato, Gabriel, additional, Malhotra, Indu, additional, Gruszczyk, Jakub, additional, Huon, Christele, additional, Lin, Enmoore, additional, Kiniboro, Benson, additional, Yadava, Anjali, additional, Siba, Peter, additional, Galinski, Mary R, additional, Healer, Julie, additional, Chitnis, Chetan, additional, Cowman, Alan F, additional, Takashima, Eizo, additional, Tsuboi, Takafumi, additional, Tham, Wai-Hong, additional, Fairhurst, Rick M, additional, Rayner, Julian C, additional, King, Christopher L, additional, and Mueller, Ivo, additional

Published
2017
Full Text
View/download PDF

24. Author response: Identification of highly-protective combinations of Plasmodium vivax recombinant proteins for vaccine development

Author

França, Camila Tenorio, primary, White, Michael T, additional, He, Wen-Qiang, additional, Hostetler, Jessica B, additional, Brewster, Jessica, additional, Frato, Gabriel, additional, Malhotra, Indu, additional, Gruszczyk, Jakub, additional, Huon, Christele, additional, Lin, Enmoore, additional, Kiniboro, Benson, additional, Yadava, Anjali, additional, Siba, Peter, additional, Galinski, Mary R, additional, Healer, Julie, additional, Chitnis, Chetan, additional, Cowman, Alan F, additional, Takashima, Eizo, additional, Tsuboi, Takafumi, additional, Tham, Wai-Hong, additional, Fairhurst, Rick M, additional, Rayner, Julian C, additional, King, Christopher L, additional, and Mueller, Ivo, additional

Published
2017
Full Text
View/download PDF

28. Age-Stratified Profiles of Serum IL-6, IL-10, and TNF-alpha Cytokines among Kenyan Children with Schistosoma haematobium, Plasmodium falciparum, and Other Chronic Parasitic Co-infections

Author

Bustinduy, Amaya L, Sutherland, Laura J, Chang-Cojulun, Alicia, Malhotra, Indu, DuVall, Adam S, Fairley, Jessica K, Mungai, Peter L, Muchiri, Eric M, Mutuku, Francis M, Kitron, Uriel, and King, Charles H

Subjects
parasitic diseases
Abstract

In a study of children having polyparasitic infections in a Schistosoma haematobium-endemic area, we examined the hypothesis that S. haematobium-positive children, compared with S. haematobium-negative children (anti-soluble worm antigen preparation [SWAP] negative and egg negative) have increased systemic production of pro-inflammatory cytokines (interleukin [IL]-6, tumor necrosis factor [TNF]-a) and decreased down-regulatory IL-10. A total of 804 children, 2-19 years of age, were surveyed between July and December 2009 and tested for S. haematobium, Plasmodium falciparum, filariasis, and soil-transmitted helminth infections. Plasma levels of IL-6, TNF-a, and IL-10 were compared for S. haematobium-positive and S. haematobium-negative children, adjusting for malaria, filaria, and hookworm co-infections, and for nutritional status, age group, sex, and geographic location. IL-10 was significantly elevated among children infected with S. haematobium, showing bimodal peaks in 7-8 and 13-14 years age groups. IL-10 was also higher among children who were acutely malnourished, whereas IL-10 levels were lower in the presence of S. haematobium-filaria co-infection. After adjustment for co-factors, IL-6 was significantly elevated among children of 5-6 years and among those with P. falciparum infection. Lower levels of IL-6 were found in malaria-hookworm co-infection. High levels of TNF-α were found in children aged 11-12 years regardless of infection status. In addition, village of residence was a strong predictor of IL-6 and IL-10 plasma levels. In adolescent children infected with S. haematobium, there is an associated elevation in circulating IL-10 that may reduce the risk of later morbidity. Although we did not find a direct link between S. haematobium infection and circulating pro-inflammatory IL-6 and TNF-α levels, future T-cell stimulation studies may provide more conclusive linkages between infection and cytokine responses in settings that are endemic for multiple parasites and multiple co-infections.

Published
2015

29. Protective Effect of Chronic Schistosomiasis in Baboons Coinfected with Schistosoma mansoni and Plasmodium knowlesi

Author

Nyakundi, Ruth K., primary, Nyamongo, Onkoba, additional, Maamun, Jeneby, additional, Akinyi, Mercy, additional, Mulei, Isaac, additional, Farah, Idle O., additional, Blankenship, D'Arbra, additional, Grimberg, Brian, additional, Hau, Jann, additional, Malhotra, Indu, additional, Ozwara, Hastings, additional, King, Christopher L., additional, and Kariuki, Thomas M., additional

Published
2016
Full Text
View/download PDF

30. Contrasting Patterns of Serologic and Functional Antibody Dynamics to Plasmodium falciparum Antigens in a Kenyan Birth Cohort

Author

Dent, Arlene E., primary, Malhotra, Indu, additional, Wang, Xuelie, additional, Babineau, Denise, additional, Yeo, Kee Thai, additional, Anderson, Timothy, additional, Kimmel, Rhonda J., additional, Angov, Evelina, additional, Lanar, David E., additional, Narum, David, additional, Dutta, Sheetij, additional, Richards, Jack, additional, Beeson, James G., additional, Crabb, Brendan S., additional, Cowman, Alan F., additional, Horii, Toshihiro, additional, Muchiri, Eric, additional, Mungai, Peter L., additional, King, Christopher L., additional, and Kazura, James W., additional

Published
2016
Full Text
View/download PDF

33. Parasitism in Children Aged Three Years and Under: Relationship between Infection and Growth in Rural Coastal Kenya

Author

LaBeaud, A. Desiree, primary, Nayakwadi Singer, Monica, additional, McKibben, Maxim, additional, Mungai, Peter, additional, Muchiri, Eric M., additional, McKibben, Elisabeth, additional, Gildengorin, Ginny, additional, Sutherland, Laura J., additional, King, Charles H., additional, King, Christopher L., additional, and Malhotra, Indu, additional

Published
2015
Full Text
View/download PDF

34. Age-Stratified Profiles of Serum IL-6, IL-10, and TNF-α Cytokines Among Kenyan Children with Schistosoma haematobium, Plasmodium falciparum, and Other Chronic Parasitic Co-Infections

Author

Bustinduy, Amaya L., primary, Muchiri, Eric M., additional, Chang-Cojulun, Alicia, additional, Mutuku, Francis M., additional, Sutherland, Laura J., additional, Kitron, Uriel, additional, DuVall, Adam S., additional, Malhotra, Indu, additional, Mungai, Peter L., additional, King, Charles H., additional, and Fairley, Jessica K., additional

Published
2015
Full Text
View/download PDF

44. Serologic Evidence of Arboviral Infections among Humans in Kenya

Author

Sutherland, Laura J., primary, Sang, Rosemary C., additional, King, Charles H., additional, LaBeaud, A. Desiree, additional, Cash, Ayla A., additional, King, Christopher L., additional, Weaver, Scott C., additional, Malhotra, Indu, additional, Huang, Yan-Jang Scott, additional, and Moormann, Ann M., additional

Published
2011
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results