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154 results on '"Mallant-Hent, Rosalie C."'

1. A Prediction Model for Successful Increase of Adalimumab Dose Intervals in Patients with Crohn’s Disease: Secondary Analysis of the Pragmatic Open-Label Randomised Controlled Non-inferiority LADI Trial

Author

van Linschoten, Reinier C. A., Jansen, Fenna M., Pauwels, Renske W. M., Smits, Lisa J. T., Atsma, Femke, Kievit, Wietske, de Jong, Dirk J., de Vries, Annemarie C., Boekema, Paul J., West, Rachel L., Bodelier, Alexander G. L., Gisbertz, Ingrid A. M., Wolfhagen, Frank H. J., Römkens, Tessa E. H., Lutgens, Maurice W. M. D., van Bodegraven, Adriaan A., Oldenburg, Bas, Pierik, Marieke J., Russel, Maurice G. V. M., de Boer, Nanne K., Mallant-Hent, Rosalie C., ter Borg, Pieter C. J., van der Meulen-de Jong, Andrea E., Jansen, Jeroen M., Jansen, Sita V., Tan, Adrianus C. I. T. L., van der Woude, C. Janneke, and Hoentjen, Frank

Published
2024
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2. Computer-aided diagnosis improves characterization of Barrett’s neoplasia by general endoscopists (with video)

Author

Alkhalaf, Alaa, Herrero, Lorenza Alvarez, Baldaque-Silva, Francisco, Barret, Maximilien, Bergman, Jacques J., Beyna, Torsten, Bisschops, Raf, Boers, Tim G., Curvers, Wouter, Deprez, Pierre H., Duits, Lucas C., Elbe, Peter, Esteban, Jose Miguel, Falk, Gary W., Fockens, Kiki N., Ginsberg, Gregory G., de Groof, Albert J., Haidry, Rehan, Houben, Martin H., Infantolino, Anthony, Iyer, Prasad G., Jong, Martijn, Jonge, Pieter-Jan de, Jukema, Jelmer B., Koch, Arjun, Komanduri, Srinadh, Konda, Vani, Kusters, Koen C., Leclerq, Philippe, Leggett, Cadman L., Lightdale, Charles J., Mallant-Hent, Rosalie C., Villarejo, Guiomar Moral, Fernández-Sordo, Jacobo Ortiz, Pech, Oliver, Penman, Ian, Pouw, Roos E., van der Putten, Joost A., Ragunath, Krish, Scholten, Pieter, Seewald, Stefan, Sethi, Amritha, Smith, Michael S., van der Sommen, Fons, Trindade, Arvind, Wani, Sachin, Waxman, Irving, Westerhof, Jessie, Weusten, Bas L., de With, Peter H., Wolfsen, Herbert C., Kusters, Carolus H.J., Jong, Martijn R., Boers, Tim, Weusten, Bas L.A.M., Houben, Martin H.M.G., Nagengast, Wouter B., Mallant-Hent, Rosalie, Silva, Francisco Baldaque, Ortiz Fernández-Sordo, Jacobo, Moral Villarejo, Guiomar, Montazeri, Nahid S.M., der Sommen, Fons van, and de Groof, A. Jeroen

Published
2024
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3. The use of a real-time computer-aided detection system for visible lesions in the Barrett’s esophagus during live endoscopic procedures: a pilot study (with video)

Author

Alkhalaf, Alaa, Herrero, Lorenza Alvarez, Baldaque-Silva, Francisco, Barret, Maximilien, Bergman, Jacques J., Beyna, Torsten, Boers, Tim G., Elbe, Peter, Fockens, Kiki N., de Groof, Albert J., Houben, Martin H., Jong, Martijn, Jukema, Jelmer B., Kusters, Koen C., Mallant-Hent, Rosalie C., Villarejo, Guiomar Moral, Nagengast, Wouter, Fernández-Sordo, Jacobo Ortiz, Pech, Oliver, Pouw, Roos E., van der Putten, Joost A., Ragunath, Krish, Scholten, Pieter, Seewald, Stefan, der Sommen, Fons van, Westerhof, Jessie, Weusten, Bas L., de With, Peter H., Jong, Martijn R., Boers, Tim, Kusters, Carolus H.J., Duits, Lucas C., van der Sommen, Fons, and de Groof, A. Jeroen

Published
2024
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4. A deep learning system for detection of early Barrett's neoplasia: a model development and validation study

Author

Alkhalaf, Alaa, Alvarez Herrero, Lorenza, Baldaque-Silva, Francisco, Barret, Maximilien, Bergman, Jacques J, Beyna, Torsten, Bisschops, Raf, Boers, Tim G, Curvers, Wouter, Deprez, Pierre H, Duits, Lucas C, Elbe, Peter, Esteban, Jose M, Falk, Gary W, Fockens, Kiki N, Ganguly, Eric, Ginsberg, Gregory G, de Groof, Albert J, Haidry, Rehan, Houben, Martin H, Infantolino, Anthony, Iyer, Prasad G, Jong, Martijn R, De Jonge, Pieter-Jan, Jukema, Jelmer B, Koch, Arjun K, Komanduri, Srinadh, Konda, Vani, Kusters, Carolus H J, Leclercq, Philippe, Leggett, Cadman L, Lemmers, Arnaud, Lightdale, Charles J, Mallant-Hent, Rosalie C, Moral Villarejo, Guiomar, Muthusamy, V Raman, Nagengast, Wouter, Ortiz Fernández-Sordo, Jacobo, Pech, Oliver, Penman, Ian, Pleskow, Douglas K, Pouw, Roos E, van der Putten, Joost A, Ragunath, Krish, Scholten, Pieter, Seewald, Stefan, Sethi, Amritha, Smith, Michael S, Van der Sommen, Fons, Trindade, Arvind, Wani, Sachin, Waxman, Irving, Westerhof, Jessie, Weusten, Bas L, de With, Peter H N, Wolfsen, Herbert C, Fockens, K N, Jong, M R, Jukema, J B, Boers, T G W, Kusters, C H J, van der Putten, J A, Pouw, R E, Duits, L C, Montazeri, N S M, van Munster, S N, Weusten, B L A M, Alvarez Herrero, L, Houben, M H M G, Nagengast, W B, Westerhof, J, Alkhalaf, A, Mallant-Hent, R C, Scholten, P, Ragunath, K, Seewald, S, Elbe, P, Baldaque-Silva, F, Barret, M, Ortiz Fernández-Sordo, J, Villarejo, G Moral, Pech, O, Beyna, T, van der Sommen, F, de With, P H, de Groof, A J, and Bergman, J J

Published
2023
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5. Increased versus conventional adalimumab dose interval for patients with Crohn's disease in stable remission (LADI): a pragmatic, open-label, non-inferiority, randomised controlled trial

Author

van Noord, Desirée, Hoekstra, Jildou, Kamphuis, Johannes T., Gorter, Moniek H.P., van Esch, Aura A.J., van Linschoten, Reinier C A, Jansen, Fenna M, Pauwels, Renske W M, Smits, Lisa J T, Atsma, Femke, Kievit, Wietske, de Jong, Dirk J, de Vries, Annemarie C, Boekema, Paul J, West, Rachel L, Bodelier, Alexander G L, Gisbertz, Ingrid A M, Wolfhagen, Frank H J, Römkens, Tessa E H, Lutgens, Maurice W M D, van Bodegraven, Adriaan A, Oldenburg, Bas, Pierik, Marieke J, Russel, Maurice G V M, de Boer, Nanne K, Mallant-Hent, Rosalie C, ter Borg, Pieter C J, van der Meulen-de Jong, Andrea E, Jansen, Jeroen M, Jansen, Sita V, Tan, Adrianus C I T L, van der Woude, C Janneke, and Hoentjen, Frank

Published
2023
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7. COMPUTER-AIDED DIAGNOSIS IMPROVES CHARACTERIZATION OF BARRETT’S NEOPLASIA BY GENERAL ENDOSCOPISTS

Author

Jukema, Jelmer B., primary, Kusters, Carolus H.J., additional, Jong, Martijn R., additional, Fockens, Kiki N., additional, Boers, Tim, additional, van der Putten, Joost A., additional, Pouw, Roos E., additional, Duits, Lucas C., additional, Weusten, BasL.A.M., additional, Herrero, Lorenza. Alvarez, additional, Houben, Martin H.M.G., additional, Nagengast, Wouter B., additional, Westerhof, Jessie, additional, Alkhalaf, Alaa, additional, Mallant-Hent, Rosalie, additional, Scholten, Pieter, additional, Ragunath, Krish, additional, Seewald, Stefan, additional, Elbe, Peter, additional, Silva, Francisco Baldaque, additional, Barret, Maximilien, additional, Fernández-Sordo, Jacobo Ortiz, additional, Villarejo, Guiomar Moral, additional, Pech, Oliver, additional, Beyna, Torsten, additional, Montazeri, Nahid S.M., additional, van der Sommen, Fons, additional, de With, Peter H., additional, de Groof, A. Jeroen, additional, Bergman, Jacques J., additional, Herrero, Lorenza Alvarez, additional, Baldaque-Silva, Francisco, additional, Bisschops, Raf, additional, Boers, Tim G., additional, Curvers, Wouter, additional, Deprez, Pierre H., additional, Esteban, Jose Miguel, additional, Falk, Gary W., additional, Ginsberg, Gregory G., additional, de Groof, Albert J., additional, Haidry, Rehan, additional, Houben, Martin H., additional, Infantolino, Anthony, additional, Iyer, Prasad G., additional, Jong, Martijn, additional, Jonge, Pieter-Jan de, additional, Jukema, Jelmer B., additional, Koch, Arjun, additional, Komanduri, Srinadh, additional, Konda, Vani, additional, Kusters, Koen C., additional, Leclerq, Philippe, additional, Leggett, Cadman L., additional, Lightdale, Charles J., additional, Mallant-Hent, Rosalie C., additional, Muthusamy, V Raman, additional, Penman, Ian, additional, Sethi, Amritha, additional, Smith, Michael S., additional, Trindade, Arvind, additional, Wani, Sachin, additional, Waxman, Irving, additional, Weusten, Bas L., additional, and Wolfsen, Herbert C., additional

Published
2024
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8. A Prediction Model for Successful Increase of Adalimumab Dose Intervals in Patients with Crohn’s Disease:Secondary Analysis of the Pragmatic Open-Label Randomised Controlled Non-inferiority LADI Trial

Author

van Linschoten, Reinier C.A., Jansen, Fenna M., Pauwels, Renske W.M., Smits, Lisa J.T., Atsma, Femke, Kievit, Wietske, de Jong, Dirk J., de Vries, Annemarie C., Boekema, Paul J., West, Rachel L., Bodelier, Alexander G.L., Gisbertz, Ingrid A.M., Wolfhagen, Frank H.J., Römkens, Tessa E.H., Lutgens, Maurice W.M.D., van Bodegraven, Adriaan A., Oldenburg, Bas, Pierik, Marieke J., Russel, Maurice G.V.M., de Boer, Nanne K., Mallant-Hent, Rosalie C., ter Borg, Pieter C.J., van der Meulen-de Jong, Andrea E., Jansen, Jeroen M., Jansen, Sita V., Tan, Adrianus C.I.T.L., van der Woude, C. Janneke, Hoentjen, Frank, van Linschoten, Reinier C.A., Jansen, Fenna M., Pauwels, Renske W.M., Smits, Lisa J.T., Atsma, Femke, Kievit, Wietske, de Jong, Dirk J., de Vries, Annemarie C., Boekema, Paul J., West, Rachel L., Bodelier, Alexander G.L., Gisbertz, Ingrid A.M., Wolfhagen, Frank H.J., Römkens, Tessa E.H., Lutgens, Maurice W.M.D., van Bodegraven, Adriaan A., Oldenburg, Bas, Pierik, Marieke J., Russel, Maurice G.V.M., de Boer, Nanne K., Mallant-Hent, Rosalie C., ter Borg, Pieter C.J., van der Meulen-de Jong, Andrea E., Jansen, Jeroen M., Jansen, Sita V., Tan, Adrianus C.I.T.L., van der Woude, C. Janneke, and Hoentjen, Frank

Abstract

Background: In the pragmatic open-label randomised controlled non-inferiority LADI trial we showed that increasing adalimumab (ADA) dose intervals was non-inferior to conventional dosing for persistent flares in patients with Crohn’s disease (CD) in clinical and biochemical remission. Aims: To develop a prediction model to identify patients who can successfully increase their ADA dose interval based on secondary analysis of trial data. Methods: Patients in the intervention group of the LADI trial increased ADA intervals to 3 and then to 4 weeks. The dose interval increase was defined as successful when patients had no persistent flare (> 8 weeks), no intervention-related severe adverse events, no rescue medication use during the study, and were on an increased dose interval while in clinical and biochemical remission at week 48. Prediction models were based on logistic regression with relaxed LASSO. Models were internally validated using bootstrap optimism correction. Results: We included 109 patients, of which 60.6% successfully increased their dose interval. Patients that were active smokers (odds ratio [OR] 0.90), had previous CD-related intra-abdominal surgeries (OR 0.85), proximal small bowel disease (OR 0.92), an increased Harvey-Bradshaw Index (OR 0.99) or increased faecal calprotectin (OR 0.997) were less likely to successfully increase their dose interval. The model had fair discriminative ability (AUC = 0.63) and net benefit analysis showed that the model could be used to select patients who could increase their dose interval. Conclusion: The final prediction model seems promising to select patients who could successfully increase their ADA dose interval. The model should be validated externally before it may be applied in clinical practice. Clinical Trial Registration Number: ClinicalTrials.gov, number NCT03172377.

Published
2024

10. A deep learning system for detection of early Barrett's neoplasia: a model development and validation study

Author

Fockens, K N, primary, Jong, M R, additional, Jukema, J B, additional, Boers, T G W, additional, Kusters, C H J, additional, van der Putten, J A, additional, Pouw, R E, additional, Duits, L C, additional, Montazeri, N S M, additional, van Munster, S N, additional, Weusten, B L A M, additional, Alvarez Herrero, L, additional, Houben, M H M G, additional, Nagengast, W B, additional, Westerhof, J, additional, Alkhalaf, A, additional, Mallant-Hent, R C, additional, Scholten, P, additional, Ragunath, K, additional, Seewald, S, additional, Elbe, P, additional, Baldaque-Silva, F, additional, Barret, M, additional, Ortiz Fernández-Sordo, J, additional, Villarejo, G Moral, additional, Pech, O, additional, Beyna, T, additional, van der Sommen, F, additional, de With, P H, additional, de Groof, A J, additional, Bergman, J J, additional, Alkhalaf, Alaa, additional, Alvarez Herrero, Lorenza, additional, Baldaque-Silva, Francisco, additional, Barret, Maximilien, additional, Bergman, Jacques J, additional, Beyna, Torsten, additional, Bisschops, Raf, additional, Boers, Tim G, additional, Curvers, Wouter, additional, Deprez, Pierre H, additional, Duits, Lucas C, additional, Elbe, Peter, additional, Esteban, Jose M, additional, Falk, Gary W, additional, Fockens, Kiki N, additional, Ganguly, Eric, additional, Ginsberg, Gregory G, additional, de Groof, Albert J, additional, Haidry, Rehan, additional, Houben, Martin H, additional, Infantolino, Anthony, additional, Iyer, Prasad G, additional, Jong, Martijn R, additional, De Jonge, Pieter-Jan, additional, Jukema, Jelmer B, additional, Koch, Arjun K, additional, Komanduri, Srinadh, additional, Konda, Vani, additional, Kusters, Carolus H J, additional, Leclercq, Philippe, additional, Leggett, Cadman L, additional, Lemmers, Arnaud, additional, Lightdale, Charles J, additional, Mallant-Hent, Rosalie C, additional, Moral Villarejo, Guiomar, additional, Muthusamy, V Raman, additional, Nagengast, Wouter, additional, Ortiz Fernández-Sordo, Jacobo, additional, Pech, Oliver, additional, Penman, Ian, additional, Pleskow, Douglas K, additional, Pouw, Roos E, additional, van der Putten, Joost A, additional, Ragunath, Krish, additional, Scholten, Pieter, additional, Seewald, Stefan, additional, Sethi, Amritha, additional, Smith, Michael S, additional, Van der Sommen, Fons, additional, Trindade, Arvind, additional, Wani, Sachin, additional, Waxman, Irving, additional, Westerhof, Jessie, additional, Weusten, Bas L, additional, de With, Peter H N, additional, and Wolfsen, Herbert C, additional

Published
2023
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12. Cost-Effectiveness Analysis of Increased Adalimumab Dose Intervals in Crohn’s Disease Patients in Stable Remission: The Randomized Controlled LADI Trial

Author

Jansen, Fenna M, primary, van Linschoten, Reinier C A, additional, Kievit, Wietske, additional, Smits, Lisa J T, additional, Pauwels, Renske W M, additional, de Jong, Dirk J, additional, de Vries, Annemarie C, additional, Boekema, Paul J, additional, West, Rachel L, additional, Bodelier, Alexander G L, additional, Gisbertz, Ingrid A M, additional, Wolfhagen, Frank H J, additional, Römkens, Tessa E H, additional, Lutgens, Maurice W M D, additional, van Bodegraven, Adriaan A, additional, Oldenburg, Bas, additional, Pierik, Marieke J, additional, Russel, Maurice G V M, additional, de Boer, Nanne K, additional, Mallant-Hent, Rosalie C, additional, ter Borg, Pieter C J, additional, van der Meulen-de Jong, Andrea E, additional, Jansen, Jeroen M, additional, Jansen, Sita V, additional, Tan, Adrianus C I T L, additional, Hoentjen, Frank, additional, and van der Woude, C Janneke, additional

Published
2023
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13. Cost-Effectiveness Analysis of Increased Adalimumab Dose Intervals in Crohn's Disease Patients in Stable Remission:The Randomized Controlled LADI Trial

Author

Jansen, Fenna M., Van Linschoten, Reinier C.A., Kievit, Wietske, Smits, Lisa J.T., Pauwels, Renske W.M., De Jong, Dirk J., De Vries, Annemarie C., Boekema, Paul J., West, Rachel L., Bodelier, Alexander G.L., Gisbertz, Ingrid A.M., Wolfhagen, Frank H.J., Römkens, Tessa E.H., Lutgens, Maurice W.M.D., Van Bodegraven, Adriaan A., Oldenburg, Bas, Pierik, Marieke J., Russel, Maurice G.V.M., De Boer, Nanne K., Mallant-Hent, Rosalie C., Ter Borg, Pieter C.J., Van Der Meulen-De Jong, Andrea E., Jansen, Jeroen M., Jansen, Sita V., Tan, Adrianus C.I.T.L., Hoentjen, Frank, Van Der Woude, C. Janneke, Van Noord, Desirée, Hoekstra, Jildou, Kamphuis, Johannes T., Gorter, Moniek H.P., Van Esch, Aura A.J., Jansen, Fenna M., Van Linschoten, Reinier C.A., Kievit, Wietske, Smits, Lisa J.T., Pauwels, Renske W.M., De Jong, Dirk J., De Vries, Annemarie C., Boekema, Paul J., West, Rachel L., Bodelier, Alexander G.L., Gisbertz, Ingrid A.M., Wolfhagen, Frank H.J., Römkens, Tessa E.H., Lutgens, Maurice W.M.D., Van Bodegraven, Adriaan A., Oldenburg, Bas, Pierik, Marieke J., Russel, Maurice G.V.M., De Boer, Nanne K., Mallant-Hent, Rosalie C., Ter Borg, Pieter C.J., Van Der Meulen-De Jong, Andrea E., Jansen, Jeroen M., Jansen, Sita V., Tan, Adrianus C.I.T.L., Hoentjen, Frank, Van Der Woude, C. Janneke, Van Noord, Desirée, Hoekstra, Jildou, Kamphuis, Johannes T., Gorter, Moniek H.P., and Van Esch, Aura A.J.

Abstract

Background and Aims: We aimed to assess cost-effectiveness of increasing adalimumab dose intervals compared to the conventional dosing interval in patients with Crohn's disease [CD] in stable clinical and biochemical remission. Design: We conducted a pragmatic, open-label, randomized controlled non-inferiority trial, comparing increased adalimumab intervals with the 2-weekly interval in adult CD patients in clinical remission. Quality of life was measured with the EQ-5D-5L. Costs were measured from a societal perspective. Results are shown as differences and incremental net monetary benefit [iNMB] at relevant willingness to accept [WTA] levels. Results: We randomized 174 patients to the intervention [n=113] and control [n=61] groups. No difference was found in utility (difference: -0.017, 95% confidence interval [-0.044; 0.004]) and total costs (-€943, [-€2226; €1367]) over the 48-week study period between the two groups. Medication costs per patient were lower (-€2545, [-€2780; -€2192]) in the intervention group, but non-medication healthcare (+€474, [+€149; +€952]) and patient costs (+€365 [+€92; €1058]) were higher. Cost-utility analysis showed that the iNMB was €594 [-€2099; €2050], €69 [-€2908; €1965] and -€455 [-€4,096; €1984] at WTA levels of €20 000, €50 000 and €80 000, respectively. Increasing adalimumab dose intervals was more likely to be cost-effective at WTA levels below €53 960 per quality-adjusted life year. Above €53 960 continuing the conventional dose interval was more likely to be cost-effective. Conclusion: When the loss of a quality-adjusted life year is valued at less than €53 960, increasing the adalimumab dose interval is a cost-effective strategy in CD patients in stable clinical and biochemical remission. Clinical Trial Registration Number: ClinicalTrials.gov, number NCT03172377.

Published
2023

15. Endoscopic trimodal imaging versus standard video endoscopy for detection of early Barrett's neoplasia: a multicenter, randomized, crossover study in general practice

Author

Curvers, Wouter L., van Vilsteren, Frederike G., Baak, Lubertus C., Böhmer, Clarisse, Mallant-Hent, Rosalie C., Naber, Anton H., van Oijen, Arnout, Ponsioen, Cyriel Y., Scholten, Pieter, Schenk, Ed, Schoon, Erik, Seldenrijk, Cees A., Meijer, Gerrit A., Kate, Fiebo J.ten, and Bergman, Jacques J.

Published
2011
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17. Additional file 1 of Evaluation of a panel of tumor-specific differentially-methylated DNA regions in IRF4, IKZF1 and BCAT1 for blood-based detection of colorectal cancer

Author

Young, Graeme P., Symonds, Erin L., Nielsen, Hans Jørgen, Ferm, Linnea, Christensen, Ib J., Dekker, Evelien, Vlugt, Manon Van Der, Mallant-Hent, Rosalie C., Boulter, Nicky, Yu, Betty, Chan, Michelle, Tevz, Gregor, LaPointe, Lawrence C., and Pedersen, Susanne K.

Abstract

Additional file 1: Figure S1. The multi-panel real-time PCR asssay. Table S1. Positivity by progression of cellular atypia (dysplasia in adenomas) and degree of invasion (T stage in cancer) in cases without disseminated disease. Table S2. Test accuracy for detection of advanced adenomas and adenomas with high grade dysplasia based on all possible combinations of genes.

Published
2021
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18. Health outcomes of 1000 children born to mothers with inflammatory bowel disease in their first 5 years of life

Author

Kanis, Shannon Linda, primary, Modderman, Sanne, additional, Escher, Johanna C, additional, Erler, Nicole, additional, Beukers, Ruud, additional, de Boer, Nanne, additional, Bodelier, Alexander, additional, Depla, Annekatrien C T.M, additional, Dijkstra, Gerard, additional, van Dijk, Anne-Baue Ruth Margaretha, additional, Gilissen, Lennard, additional, Hoentjen, Frank, additional, Jansen, Jeroen M, additional, Kuyvenhoven, Johan, additional, Mahmmod, Nofel, additional, Mallant-Hent, Rosalie C, additional, van der Meulen-de Jong, Andrea E, additional, Noruzi, Anahita, additional, Oldenburg, Bas, additional, Oostenbrug, Liekele E, additional, Ter Borg, Pieter C.J., additional, Pierik, Marieke, additional, Romberg- Camps, Mariëlle, additional, Thijs, Willem, additional, West, Rachel, additional, de Lima, Alison, additional, and van der Woude, C Janneke, additional

Published
2020
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19. Implementation of population screening for colorectal cancer by repeated Fecal Immunochemical Test (FIT): third round

Author

Stegeman Inge, de Wijkerslooth Thomas R, Mallant-Hent Rosalie C, de Groot Karin, Stroobants An K, Fockens Paul, Mundt Marco, Bossuyt Patrick MM, and Dekker Evelien

Subjects
Diseases of the digestive system. Gastroenterology, RC799-869
Abstract

Abstract Background Colorectal cancer (CRC) is the most common cancer in Europe with a mortality rate of almost 50%. The prognosis of patients is largely determined by the clinical and pathological stage at the time of diagnosis. Population screening has been shown to reduce CRC-related mortality rate. Most screening programs worldwide rely on fecal immunochemical testing (FIT). The effectiveness of a FIT screening program is not only influenced by initial participation rate, but also by program adherence during consecutive screening rounds. We aim to evaluate the participation rate in and yield of a third CRC screening round using FIT. Methods and design Four years after the first screening round and two years after the second round, a total number of approximately 11,000 average risk individuals (50 to 75 years of age) will be invited to participate in a third round of FIT-based CRC screening. We will select individuals in the same target area as in the previous screening rounds, using the electronic database of the regional municipal administration registrations. We will invite all FIT-negatives and all non-participants in previous screening rounds, as well as eligible first time invitees who have moved into the area or have become 50 years of age. FITs will be analyzed in the special technique laboratory of the Academic Medical Center of the University of Amsterdam. All FIT-positives will be invited for a consultation at the outpatient clinic. In the absence of contra-indications, a colonoscopy will follow at the Academic Medical Center or at the Flevohospital. The primary outcome measures are the participation rate, defined as the proportion of invitees that return a FIT in this third round of FIT-screening, and the diagnostic yield of the program. Implications This study will provide precise data on the participation in later FIT screening rounds. This enables to estimate the effectiveness of CRC screening programs that rely on repeated FIT- screening, such as the one that will be implemented in the Netherlands in 2013.

Published
2012
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20. Health outcomes of 1000 children born to mothers with inflammatory bowel disease in their first 5 years of life.

Author

Kanis, Shannon Linda, Modderman, Sanne, Escher, Johanna C., Erler, Nicole, Beukers, Ruud, de Boer, Nanne, Bodelier, Alexander, Depla, Annekatrien C. T. M., Dijkstra, Gerard, van Dijk, Anne-Baue Ruth Margaretha, Gilissen, Lennard, Hoentjen, Frank, Jansen, Jeroen M., Kuyvenhoven, Johan, Mahmmod, Nofel, Mallant-Hent, Rosalie C., van der Meulen-de, Andrea E., Noruzi, Anahita, Oldenburg, Bas, and Oostenbrug, Liekele E.

Subjects
INFLAMMATORY bowel diseases, MOTHER-child relationship, IMMUNIZATION of children, TYPE 1 diabetes, SMALL for gestational age, LOW birth weight, PEDIATRIC gastroenterology
Published
2021
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21. The Amsterdam ReBus progressor cohort : Identification of 165 Barrett's surveillance patients who progressed to early neoplasia and 723 nonprogressor patients

Author

Duits, L. C., Klaver, E., Bureo Gonzalez, A., Boerwinkel, D. F., Ten Kate, F. J.W., Offerhaus, G. J.A., Meijer, S. L., Visser, M., Seldenrijk, C. A., Krishnadath, K. K., Schoon, E. J., Weusten, Bas L.A.M., Mallant-Hent, Rosalie C., Pouw, Roos E., Bergman, Jacques J.G.H.M., Duits, L. C., Klaver, E., Bureo Gonzalez, A., Boerwinkel, D. F., Ten Kate, F. J.W., Offerhaus, G. J.A., Meijer, S. L., Visser, M., Seldenrijk, C. A., Krishnadath, K. K., Schoon, E. J., Weusten, Bas L.A.M., Mallant-Hent, Rosalie C., Pouw, Roos E., and Bergman, Jacques J.G.H.M.

Published
2019

22. The Amsterdam ReBus progressor cohort: Identification of 165 Barrett's surveillance patients who progressed to early neoplasia and 723 nonprogressor patients

Author

Pathologie Histochemie en Em, Pathologie Pathologen staf, Cancer, Duits, L. C., Klaver, E., Bureo Gonzalez, A., Boerwinkel, D. F., Ten Kate, F. J.W., Offerhaus, G. J.A., Meijer, S. L., Visser, M., Seldenrijk, C. A., Krishnadath, K. K., Schoon, E. J., Weusten, Bas L.A.M., Mallant-Hent, Rosalie C., Pouw, Roos E., Bergman, Jacques J.G.H.M., Pathologie Histochemie en Em, Pathologie Pathologen staf, Cancer, Duits, L. C., Klaver, E., Bureo Gonzalez, A., Boerwinkel, D. F., Ten Kate, F. J.W., Offerhaus, G. J.A., Meijer, S. L., Visser, M., Seldenrijk, C. A., Krishnadath, K. K., Schoon, E. J., Weusten, Bas L.A.M., Mallant-Hent, Rosalie C., Pouw, Roos E., and Bergman, Jacques J.G.H.M.

Published
2019

23. The Amsterdam ReBus progressor cohort: identification of 165 Barrett's surveillance patients who progressed to early neoplasia and 723 nonprogressor patients

Author

Duits, L C, primary, Klaver, E, additional, Bureo Gonzalez, A, additional, Boerwinkel, D F, additional, ten Kate, F J W, additional, Offerhaus, G J A, additional, Meijer, S L, additional, Visser, M, additional, Seldenrijk, C A, additional, Krishnadath, K K, additional, Schoon, E J, additional, Weusten, Bas L A M, additional, Mallant-Hent, Rosalie C, additional, Pouw, Roos E, additional, and Bergman, Jacques J G H M, additional

Published
2018
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24. The ACCURE-trial: the effect of appendectomy on the clinical course of ulcerative colitis, a randomised international multicenter trial (NTR2883) and the ACCURE-UK trial: a randomised external pilot trial (ISRCTN56523019)

Author

Gardenbroek, Tjibbe J., Pinkney, Thomas D., Sahami, Saloomeh, Morton, Dion G., Buskens, Christianne J., Ponsioen, Cyriel Y., Tanis, Pieter J., Löwenberg, Mark, van den Brink, Gijs R., Broeders, Ivo A. M. J., Pullens, Hendrikus J. M., Pullens, Paul H. J. M., Seerden, Tom, Boom, Maarten J., Mallant-Hent, Rosalie C., Pierik, Robert E. G. J. M., Vecht, Juda, Sosef, Meindert N., van Nunen, Annick B., van Wagensveld, Bart A., Stokkers, Pieter C. F., Gerhards, Michael F., Jansen, Jeroen M., Acherman, Yair, Depla, Annekatrien C. T. M., Mannaerts, Guido H. H., West, Rachel, Iqbal, Tariq, Pathmakanthan, Shrikanth, Howard, Rebecca, Magill, Laura, Singh, Baljit, Oo, Ye H., Htun Oo, Ye, Negpodiev, Dmitri, Dijkgraaf, Marcel G. W., D'Haens, Geert R. A. M., Bemelman, Willem A., Other departments, Graduate School, AGEM - Amsterdam Gastroenterology Endocrinology Metabolism, Surgery, Gastroenterology and Hepatology, AII - Amsterdam institute for Infection and Immunity, and Clinical Research Unit

Subjects
medicine.medical_specialty, Colectomies, business.industry, Standard treatment, General Medicine, medicine.disease, Ulcerative colitis, Inflammatory bowel disease, Surgery, law.invention, Clinical trial, Study Protocol, Randomized controlled trial, law, Multicenter trial, Medicine, Appendectomy, Disease course, business, Prospective cohort study
Abstract

Background: Over the past 20 years evidence has accumulated confirming the immunomodulatory role of the appendix in ulcerative colitis (UC). This led to the idea that appendectomy might alter the clinical course of established UC. The objective of this body of research is to evaluate the short-term and medium-term efficacy of appendectomy to maintain remission in patients with UC, and to establish the acceptability and cost-effectiveness of the intervention compared to standard treatment. Methods/Design: These paired phase III multicenter prospective randomised studies will include patients over 18 years of age with an established diagnosis of ulcerative colitis and a disease relapse within 12 months prior to randomisation. Patients need to have been medically treated until complete clinical (Mayo score

Published
2015

25. Patients With Barrett's Esophagus and Confirmed Persistent Low-Grade Dysplasia Are at Increased Risk for Progression to Neoplasia

Author

Pathologie patiënten zorg, Cancer, Duits, Lucas C., van der Wel, Myrtle J., Cotton, Cary C., Phoa, K. Nadine, ten Kate, Fiebo J W, Seldenrijk, Cees A., Offerhaus, G. Johan A, Visser, Mike, Meijer, Sybren L., Mallant-Hent, Rosalie C., Krishnadath, Kausilia K., Pouw, Roos E., Tijssen, Jan G P, Shaheen, Nicholas J., Bergman, Jacques J G H M, Pathologie patiënten zorg, Cancer, Duits, Lucas C., van der Wel, Myrtle J., Cotton, Cary C., Phoa, K. Nadine, ten Kate, Fiebo J W, Seldenrijk, Cees A., Offerhaus, G. Johan A, Visser, Mike, Meijer, Sybren L., Mallant-Hent, Rosalie C., Krishnadath, Kausilia K., Pouw, Roos E., Tijssen, Jan G P, Shaheen, Nicholas J., and Bergman, Jacques J G H M

Published
2017

26. Burden of disease and increasing prevalence of inflammatory bowel disease in a population-based cohort in the Netherlands

Author

de Groof, E. Joline, primary, Rossen, Noortje G.M., additional, van Rhijn, Bram D., additional, Karregat, Evert P.M., additional, Boonstra, Kirsten, additional, Hageman, Ishtu, additional, Bennebroek Evertsz, Floor, additional, Kingma, Paul J., additional, Naber, Anton H.J., additional, van den Brande, Jan H.M., additional, Mallant-Hent, Rosalie C., additional, Mundt, Marco W., additional, D’Haens, Geert R.A.M., additional, and Ponsioen, Cyriel Y., additional

Published
2016
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27. Dynamic clonal equilibrium and predetermined cancer risk in Barrett’s oesophagus

Author

Martinez, Pierre, primary, Timmer, Margriet R., additional, Lau, Chiu T., additional, Calpe, Silvia, additional, Sancho-Serra, Maria del Carmen, additional, Straub, Danielle, additional, Baker, Ann-Marie, additional, Meijer, Sybren L., additional, Kate, Fiebo J. W. ten, additional, Mallant-Hent, Rosalie C., additional, Naber, Anton H. J., additional, van Oijen, Arnoud H. A. M., additional, Baak, Lubbertus C., additional, Scholten, Pieter, additional, Böhmer, Clarisse J. M., additional, Fockens, Paul, additional, Bergman, Jacques J. G. H. M., additional, Maley, Carlo C., additional, Graham, Trevor A., additional, and Krishnadath, Kausilia K, additional

Published
2016
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28. Erratum to: The ACCURE-trial: the effect of appendectomy on the clinical course of ulcerative colitis, a randomised international multicenter trial (NTR2883) and the ACCURE-UK trial: a randomised external pilot trial (ISRCTN56523019)

Author

Gardenbroek, Tjibbe J., primary, Pinkney, Thomas D., additional, Sahami, Saloomeh, additional, Morton, Dion G., additional, Buskens, Christianne J., additional, Ponsioen, Cyriel Y., additional, Tanis, Pieter J., additional, Löwenberg, Mark, additional, van den Brink, Gijs R., additional, Broeders, Ivo A. M. J., additional, Pullens, Hendrikus J. M., additional, Seerden, Tom, additional, Boom, Maarten J., additional, Mallant-Hent, Rosalie C., additional, Pierik, Robert E. G. J. M., additional, Vecht, Juda, additional, Sosef, Meindert N., additional, van Nunen, Annick B., additional, van Wagensveld, Bart A., additional, Stokkers, Pieter C. F., additional, Gerhards, Michael F., additional, Jansen, Jeroen M., additional, Acherman, Yair, additional, Depla, Annekatrien C. T. M., additional, Mannaerts, Guido H. H., additional, West, Rachel, additional, Iqbal, Tariq, additional, Pathmakanthan, Shrikanth, additional, Howard, Rebecca, additional, Magill, Laura, additional, Singh, Baljit, additional, Oo, Ye H., additional, Negpodiev, Dmitri, additional, Dijkgraaf, Marcel G. W., additional, D’Haens, Geert R. A. M., additional, and Bemelman, Willem A., additional

Published
2016
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29. Barrett's oesophagus patients with low-grade dysplasia can be accurately risk-stratified after histological review by an expert pathology panel

Author

Duits, Lucas C., Phoa, K. Nadine, Curvers, Wouter L., Ten Kate, Fiebo J W, Meijer, Gerrit A., Seldenrijk, Cees A., Offerhaus, G. Johan, Visser, Mike, Meijer, Sybren L., Krishnadath, Kausilia K., Tijssen, Jan G P, Mallant-Hent, Rosalie C., Bergman, Jacques J G H M, Duits, Lucas C., Phoa, K. Nadine, Curvers, Wouter L., Ten Kate, Fiebo J W, Meijer, Gerrit A., Seldenrijk, Cees A., Offerhaus, G. Johan, Visser, Mike, Meijer, Sybren L., Krishnadath, Kausilia K., Tijssen, Jan G P, Mallant-Hent, Rosalie C., and Bergman, Jacques J G H M

Published
2015

30. Barrett's oesophagus patients with low-grade dysplasia can be accurately risk-stratified after histological review by an expert pathology panel

Author

Pathologie Pathologen staf, Cancer, Duits, Lucas C., Phoa, K. Nadine, Curvers, Wouter L., Ten Kate, Fiebo J W, Meijer, Gerrit A., Seldenrijk, Cees A., Offerhaus, G. Johan, Visser, Mike, Meijer, Sybren L., Krishnadath, Kausilia K., Tijssen, Jan G P, Mallant-Hent, Rosalie C., Bergman, Jacques J G H M, Pathologie Pathologen staf, Cancer, Duits, Lucas C., Phoa, K. Nadine, Curvers, Wouter L., Ten Kate, Fiebo J W, Meijer, Gerrit A., Seldenrijk, Cees A., Offerhaus, G. Johan, Visser, Mike, Meijer, Sybren L., Krishnadath, Kausilia K., Tijssen, Jan G P, Mallant-Hent, Rosalie C., and Bergman, Jacques J G H M

Published
2015

31. Derivation of genetic biomarkers for cancer risk stratification in Barrett’s oesophagus: a prospective cohort study

Author

Timmer, Margriet R, primary, Martinez, Pierre, additional, Lau, Chiu T, additional, Westra, Wytske M, additional, Calpe, Silvia, additional, Rygiel, Agnieszka M, additional, Rosmolen, Wilda D, additional, Meijer, Sybren L, additional, ten Kate, Fiebo J W, additional, Dijkgraaf, Marcel G W, additional, Mallant-Hent, Rosalie C, additional, Naber, Anton H J, additional, van Oijen, Arnoud H A M, additional, Baak, Lubbertus C, additional, Scholten, Pieter, additional, Böhmer, Clarisse J M, additional, Fockens, Paul, additional, Maley, Carlo C, additional, Graham, Trevor A, additional, Bergman, Jacques J G H M, additional, and Krishnadath, Kausilia K, additional

Published
2015
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32. 434 Adenoma Detection With Endocuff Colonoscopy vs Conventional Colonoscopy: a Multicenter Randomised Controlled Trial

Author

Van Doorn, Sascha C., primary, Van Der Vlugt, Manon, additional, Depla, Annekatrien C., additional, Wientjes, Caroline A., additional, Mundt, Marco W., additional, Siersema, Peter D., additional, Tytgat, Kristien M., additional, Tuynman, Henriëtte, additional, Kuiken, Sjoerd D., additional, Mallant-Hent, Rosalie C., additional, Stokkers, Pieter, additional, Moons, Leon M., additional, Fockens, Paul, additional, Houben, Peter, additional, and Dekker, Evelien, additional

Published
2015
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33. Su1923 The Amsterdam ReBus Progressor Cohort: Identification of 153 Barrett's Surveillance Patients Who Progressed to Early Neoplasia and 1,098 Non-Progressor Patients

Author

Duits, Lucas C., primary, Gonzalez, Angela Bureo, additional, Boerwinkel, David F., additional, Ten Kate, Fiebo T., additional, Offerhaus, Johan, additional, Meijer, Sybren L., additional, Visser, Mike, additional, Seldenrijk, Cees A., additional, Krishnadath, Kausilia K., additional, Schoon, Erik J., additional, Weusten, Bas L., additional, Mallant-Hent, Rosalie C., additional, Pouw, Roos E., additional, and Bergman, Jacques J., additional

Published
2015
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34. Su1313 Epidemiology and Characteristics of Inflammatory Bowel Disease in a Large Population-Based Cohort in the Netherlands

Author

de Groof, Elisabeth J., primary, Rossen, Noortje, additional, van Rhijn, Bram D., additional, Karregat, Evert, additional, Boonstra, Kirsten, additional, Hageman, Ishtu, additional, Kingma, Paul, additional, Naber, Anton H., additional, Brande, Jan V., additional, Mallant-Hent, Rosalie C., additional, Mundt, Marco W., additional, D'Haens, Geert R., additional, and Ponsioen, Cyriel, additional

Published
2015
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35. 817 The SURF-Trial Pre-Assessment Cohort: A Multivariable Model Accurately Predicts Neoplastic Progression in Barrett's Esophagus Patients With Low-Grade Dysplasia

Author

Duits, Lucas C., primary, Cotton, Cary C., additional, Phoa, Kai Yi N., additional, Ten Kate, Fiebo T., additional, Seldenrijk, Cees A., additional, Offerhaus, Johan, additional, Visser, Mike, additional, Meijer, Sybren L., additional, Mallant-Hent, Rosalie C., additional, Krishnadath, Kausilia K., additional, Pouw, Roos E., additional, Tijssen, Jan, additional, Shaheen, Nicholas J., additional, and Bergman, Jacques J., additional

Published
2015
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36. Barrett's oesophagus patients with low-grade dysplasia can be accurately risk-stratified after histological review by an expert pathology panel

Author

Duits, Lucas C, primary, Phoa, K Nadine, additional, Curvers, Wouter L, additional, ten Kate, Fiebo J W, additional, Meijer, Gerrit A, additional, Seldenrijk, Cees A, additional, Offerhaus, G Johan, additional, Visser, Mike, additional, Meijer, Sybren L, additional, Krishnadath, Kausilia K, additional, Tijssen, Jan G P, additional, Mallant-Hent, Rosalie C, additional, and Bergman, Jacques J G H M, additional

Published
2014
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37. Tu1311 A FISH Biomarker Panel for Distinguishing Different Stages of Dysplasia in Barrett's Esophagus

Author

Timmer, Margriet R., primary, Lau, Chiu Ting, additional, Rosmolen, Wilda, additional, Meijer, Sybren L., additional, Dijkgraaf, Marcel G., additional, Mallant-Hent, Rosalie C., additional, Naber, Anton H., additional, Van Oijen, Arnoud H., additional, Baak, Lubbertus C., additional, Scholten, Pieter, additional, BöHmer, Clarisse, additional, Fockens, Paul, additional, Bergman, Jacques J., additional, and Krishnadath, Kausilia K., additional

Published
2014
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38. 228 Evaluation of a 2-Gene (IKZF1 and BCAT1) DNA Blood Test for Detection of Colorectal Cancer

Author

Young, Graeme P., primary, Pedersen, Susanne K., additional, Dekker, Evelien, additional, Cole, Stephen R., additional, Osborne, Joanne M., additional, Symonds, Erin L., additional, Mallant-Hent, Rosalie C., additional, McEvoy, Aidan, additional, Baker, Rohan, additional, Gaur, Snigdha, additional, Murray, David H., additional, and LaPointe, Lawrence C., additional

Published
2014
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39. 164 A FISH Biomarker Panel for the Prediction of High-grade Dysplasia and Adenocarcinoma in Non-Dysplastic Barrett's Esophagus; Results From a Long-Term Prospective Cohort Study

Author

Timmer, Margriet R., primary, Lau, Chiu Ting, additional, Rosmolen, Wilda, additional, Meijer, Sybren L., additional, Dijkgraaf, Marcel G., additional, Mallant-Hent, Rosalie C., additional, Naber, Anton H., additional, Van Oijen, Arnoud H., additional, Baak, Lubbertus C., additional, Scholten, Pieter, additional, BöHmer, Clarisse, additional, Fockens, Paul, additional, Bergman, Jacques J., additional, and Krishnadath, Kausilia K., additional

Published
2014
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40. Patients’ perception of colonoscopy

Author

Denters, Maaike J., primary, Schreuder, Marthe, additional, Depla, Annekatrien C.T.M., additional, Mallant-Hent, Rosalie C., additional, van Kouwen, Mariette C.A., additional, Deutekom, Marije, additional, Bossuyt, Patrick M., additional, Fockens, Paul, additional, and Dekker, Evelien, additional

Published
2013
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44. 384 Low-Grade Dysplasia in Barrett's Esophagus Has a High Risk of Progression When Confirmed by a Panel of Expert Pathologists

Author

Duits, Lucas C., primary, Phoa, Kai Yi N., additional, Curvers, Wouter L., additional, ten Kate, Fiebo J., additional, Meijer, Gerrit A., additional, Seldenrijk, Cees A., additional, Offerhaus, Johan, additional, Visser, Mike, additional, Meijer, Sybren L., additional, Krishnadath, Kausilia K., additional, Mallant-Hent, Rosalie C., additional, and Bergman, Jacques J., additional

Published
2013
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45. Derivation of genetic biomarkers for cancer risk stratification in Barrett's oesophagus: a prospective cohort study.

Author

Timmer, Margriet R., Martinez, Pierre, Lau, Chiu T., Westra, Wytske M., Calpe, Silvia, Rygiel, Agnieszka M., Rosmolen, Wilda D., Meijer, Sybren L., ten Kate, Fiebo J. W., Dijkgraaf, Marcel G. W., Mallant-Hent, Rosalie C., Naber, Anton H. J., van Oijen, Arnoud H. A. M., Baak, Lubbertus C., Scholten, Pieter, Böhmer, Clarisse J. M., Fockens, Paul, Maley, Carlo C., Graham, Trevor A., and Bergman, Jacques J. G. H. M.

Subjects
BARRETT'S esophagus, GENETIC markers, CANCER risk factors, DISEASE progression, ENDOSCOPY, DIAGNOSIS, THERAPEUTICS
Published
2016
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46. Su1181 A Diagnostic DNA FISH Biomarker Assay Identifies HGD or EAC in Barrett Esophagus

Author

Pacha, Alifiya, primary, Rygiel, Agnieszka M., additional, Westra, Wytske, additional, Dijkgraaf, Marcel G., additional, Rosmolen, Wilda, additional, Visser, Mike, additional, ten Kate, Fiebo J., additional, Bohmer, Clarisse, additional, Naber, Anton H., additional, van Oijen, Arnoud H., additional, Baak, Bert C., additional, Scholten, Pieter, additional, Mallant-Hent, Rosalie C., additional, Bergman, Jacques J., additional, and Krishnadath, Kausilia K., additional

Published
2012
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47. Tu1098 Validation of a Novel Prognostic DNA FISH Biomarker Assay in a Random Barrett Esophagus Cohort: Preliminary Results From a Phase IV Long Term Prospective Follow up Study

Author

Pacha, Alifiya, primary, Visser, Mike, additional, ten Kate, Fiebo J., additional, Dijkgraaf, Marcel G., additional, Mallant-Hent, Rosalie C., additional, Naber, Anton H., additional, van Oijen, Arnoud H., additional, Baak, Bert C., additional, Scholten, Pieter, additional, Bohmer, Clarisse, additional, Bergman, Jacques J., additional, and Krishnadath, Kausilia K., additional

Published
2012
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48. Tu1567 Prospective Long-Term Follow-Up After Radiofrequency Ablation for Barrett's Esophagus With High-Grade Dysplasia and/or Early Cancer

Author

Phoa, Kai Yi N., primary, Pouw, Roos E., additional, Van Vilsteren, Frederike G., additional, Sondermeijer, Carine, additional, Ten Kate, Fiebo J., additional, Visser, Mike, additional, Meijer, Sybren L., additional, Van Berge Henegouwen, Mark I., additional, Weusten, Bas L., additional, Mallant-Hent, Rosalie C., additional, Schoon, Erik J., additional, and Bergman, Jacques J., additional

Published
2012
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50. Sa1529 Radiofrequency Ablation +/- Endoscopic Resection for Barrett's Esophagus With High-Grade Dysplasia and/or Early Cancer: Durability of the Post-Treatment Neosquamous Epithelium At 5-Year Follow-Up

Author

Phoa, Kai Yi N., primary, Pouw, Roos E., additional, Van Vilsteren, Frederike G., additional, Sondermeijer, Carine, additional, Herrero, Lorenza Alvarez, additional, Ten Kate, Fiebo J., additional, Visser, Mike, additional, Van Berge Henegouwen, Mark I., additional, Weusten, Bas L., additional, Mallant-Hent, Rosalie C., additional, and Bergman, Jacques J., additional

Published
2011
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