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C44H42N4O15P4Cd2Si, triclinic, P1̄ (no. 2), a = 13.4778(9) Å, b = 14.2036(9) Å, c = 15.2206(10) Å, α = 69.637(1)°, β = 72.355(1)°, γ = 64.861(1)°, V = 2431.1(3) Å3, Z = 2, Rgt(F) = 0.0428, wRref(F2) = 0.0987, T = 120(2) K.

C6H15NO5S, monoclinic, Cc (no. 9), a = 15.167(5) Å, b = 6.422(5) Å, c = 10.969(5) Å, β = 117.407(5)°, V = 948.5(9) Å3, Z = 4, Rgt(F) = 0.0278, wRref(F2) = 0.0755, T = 293(2) K.

The comparison of ibuprofen with acetaminophen for blood pressure (BP) in preeclampsia remains controversial. We conduct a systematic review and meta-analysis to compare the impact of ibuprofen versus acetaminophen on BP for preeclampsia. We search PubMed, Embase, Web of Science, EBSCO, and Cochrane Library databases through October 2019 for randomized controlled trials (RCTs) assessing the effect of ibuprofen versus acetaminophen on BP for preeclampsia. This meta-analysis is performed using the random-effect model. Four RCTs are included in the meta-analysis. Overall in preeclampsia patients, ibuprofen and acetaminophen show similar systolic BP (SBP) (standard mean difference [SMD] = 0.04; 95% CI = −0.26–0.34; p=.81), diastolic BP (DBP) (SMD = 0.15; 95% CI = −0.18–0.48; p = 0.38), mean BP (MAP) (SMD = 0.02; 95% CI = −0.29–0.33; p =.91), severe range BP (SMD = −0.10; 95% CI = −0.40–0.19; p =.50), severe hypertension (SMD = 1.18; 95% CI = 0.85–1.62; p =.32), and satisfaction level (SMD = 1.2; 95% CI = 0.95–1.53; p =.13). Ibuprofen and acetaminophen may have no significant influence on BP for preeclampsia. [ABSTRACT FROM AUTHOR]

BACKGROUND: Foxtail millet grain has higher folate content than other cereal crops. However, the folate metabolite content and the expression patterns of folate metabolite‐related genes are unknown. RESULTS: Liquid chromatography–mass spectrometry was used to investigate 12 folate metabolites in a foxtail millet panicle. The content of total folate and derivatives gradually decreased during panicle development. Polyglutamate 5‐formyl‐tetrahydrofolate was the major form. Twenty‐eight genes involved in the folate metabolic pathway were identified through bioinformatic analysis. These genes in Setaria italica, S. viridis and Zea mays showed genomic collinearity. Phylogenetic analysis revealed that the folate‐related genes were closely related among the C4 plants compared to C3 plants. The gene expressions were then studied at three panicle development stages. The gene expression patterns were classified into two groups, namely SiADCL1 and SiGGH as two key enzymes, which are responsible for folate synthesis and degradation; their expression levels were highest at the early panicle development stage, up to 179.11‐ and 163.88‐fold, respectively. Their expression levels had a similar downward trend during panicle development and were significantly positively correlated with the concentration of total folate and folate derivatives. However, SiSHMT3 expression levels were significantly negatively correlated with total folate concentration. CONCLUSION: Besides being the major determinants of folate and folate derivatives accumulation, SiADCL1 and SiGGH expression levels are key limiting factors in the foxtail millet panicle. Therefore, SiADCL1 and SiGGH expression levels can be targeted in genetic modification studies to improve folate content in foxtail millet seeds in the future. © 2021 Society of Chemical Industry [ABSTRACT FROM AUTHOR]

Red emission is one of the three primary colors that are essential for the realization of full‐color displays and solid‐state lightings. A high solid‐state efficiency is a crucial factor for the applications in organic light‐emitting diodes (OLEDs). In this work, two new donor‐acceptor‐donor type phenanthro[9,10‐d]imidazole (PIM)‐based derivatives, (2Z,2′Z)‐2,2′‐(1,4‐phenylene)bis(3‐(4‐(1‐phenyl‐1H‐phenanthro[9,10‐d]imidazol‐2‐yl)phenyl)acrylonitrile) (PIDSB) and 2,3‐bis(4′‐(1‐phenyl‐1H‐phenanthro[9,10‐d]imidazol‐2‐yl)‐[1,1′‐biphenyl]‐4‐yl)fumaronitrile (PIDPh), are designed and synthesized. Both of them possess high thermal stabilities. PIDPh shows typical characteristics of aggregation‐induced emission enhancement, while PIDSB displays an aggregation‐caused quenching effect. They both exhibit significant red‐shifted emissions compared with PIM owing to intramolecular charge transfer. In the film state, the emission peaks of PIDSB and PIDPh are located at 538 nm and 605 nm with high photoluminescent quantum yields of 63.82 % and 41.26 %, respectively. The non‐doped OLED using PIDPh as the active layer shows the maximum external quantum efficiency of 2.06 % with a very low efficiency roll‐off, and exhibits the electroluminescent peak at 640 nm with a Commission Internationale de l′Éclairage coordinate of (0.617,0.396), meeting well the criteria of red OLEDs. OLED, OLED, OLED: AIEE‐active PIDPh exhibits a high photoluminescent quantum yield (PLQY) of 41.26 % and a significant red‐shifted emission compared with PIM owing to intramolecular charge transfer. A non‐doped OLED using PIDPh as the active layer shows an external quantum efficiency (EQE) of 2.06 % with a low efficiency roll‐off. The EL peak located at 640 nm with a CIE coordinate of (0.617, 0.396), meeting well the criteria of red OLEDs. [ABSTRACT FROM AUTHOR]

C44H42N4O15P4Cd2Si, triclinic, P1̄ (no. 2), a = 13.4778(9) Å, b = 14.2036(9) Å, c = 15.2206(10) Å, α = 69.637(1)°, β = 72.355(1)°, γ = 64.861(1)°, V = 2431.1(3) Å3, Z = 2, Rgt(F) = 0.0428, wRref(F2) = 0.0987, T = 120(2) K. [ABSTRACT FROM AUTHOR]

Background: Many studies have investigated the relationship between the interleukin-1β gene ( IL1B ) -511C/T polymorphism and the risk of Behçet's disease (BD); however, the conclusions remain controversial., Methods: In this study, we systemically retrieved relevant studies from the Chinese Biomedicine Database, China National Knowledge Infrastructure, Embase, Cochrane Library, and PubMed databases. We then calculated the odds ratios (ORs) and 95% confidence intervals (CIs) using the meta-package Stata version 12.0., Results: The IL1B -511C/T polymorphism was not related to BD susceptibility using any of the tested models (C vs T: OR = 1.20, 95% CI = 0.97-1.49; CC vs TT: OR = 1.27, 95% CI = 0.95-1.70; CT vs TT: OR = 1.03, 95% CI = 0.781.36; dominant model: OR = 1.12, 95% CI = 0.87-1.46; recessive model: OR = 1.27, 95% CI = 0.89-1.82). Similarly, subgroup analysis including studies consistent with the Hardy-Weinberg equilibrium revealed no association between the IL1B polymorphism and BD susceptibility., Conclusion: This meta-analysis indicates that the IL1B -511C/T polymorphism is unlikely to affect the risk of BD; however, further large-scale, carefully designed studies are needed to verify these results.

Red emission is one of the three primary colors that are essential for the realization of full-color displays and solid-state lightings. A high solid-state efficiency is a crucial factor for the applications in organic light-emitting diodes (OLEDs). In this work, two new donor-acceptor-donor type phenanthro[9,10-d]imidazole (PIM)-based derivatives, (2Z,2'Z)-2,2'-(1,4-phenylene)bis(3-(4-(1-phenyl-1H-phenanthro[9,10-d]imidazol-2-yl)phenyl)acrylonitrile) (PIDSB) and 2,3-bis(4'-(1-phenyl-1H-phenanthro[9,10-d]imidazol-2-yl)-[1,1'-biphenyl]-4-yl)fumaronitrile (PIDPh), are designed and synthesized. Both of them possess high thermal stabilities. PIDPh shows typical characteristics of aggregation-induced emission enhancement, while PIDSB displays an aggregation-caused quenching effect. They both exhibit significant red-shifted emissions compared with PIM owing to intramolecular charge transfer. In the film state, the emission peaks of PIDSB and PIDPh are located at 538 nm and 605 nm with high photoluminescent quantum yields of 63.82 % and 41.26 %, respectively. The non-doped OLED using PIDPh as the active layer shows the maximum external quantum efficiency of 2.06 % with a very low efficiency roll-off, and exhibits the electroluminescent peak at 640 nm with a Commission Internationale de l'Éclairage coordinate of (0.617,0.396), meeting well the criteria of red OLEDs., (© 2019 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.)