Search

Your search keyword '"Mancardi, G"' showing total 852 results
Start Over Author "Mancardi, G"
852 results on '"Mancardi, G"'

4. Haematopoietic stem cell transplantation for severe autoimmune diseases in children : a review of current literature, registry activity and future directions on behalf of the autoimmune diseases and paediatric diseases working parties of the European Society for Blood and Marrow Transplantation

Author

Achini‐Gutzwiller, FR, Snowden, JA, Corbacioglu, S, Greco, R, Alexander, T, Snowden, J, Badoglio, M, Labopin, M, Abinun, M, Apte, S, Arnold, R, Domenech, A, Brierley, C, Burman, J, Castilla‐Llorente, C, Cooper, N, Daghia, G, Daikeler, T, del Papa, N, de Vries‐Bouwstra, J, Farge, D, Finke, J, Hagglund, H, Hawkey, C, Henes, J, Hiepe, F, Jessop, H, Kiely, D, Kazmi, M, Kirgizov, K, Kramer, E, Mancardi, G, Marjanovic, Z, Martin, R, Martin, T, Ma, D, Moore, J, Miller, P, Muraro, P, Oliveira, M, Polushin, A, Onida, F, Simoes, B, Puyade, M, Resnick, I, Ricart, E, Rovira, M, Saccardi, R, Saif, M, Sakellari, I, Sharrack, B, Snarski, E, Scherer, HU, Sossa, C, Withers, B, Wulffraat, N, Zaccara, E, Amrolia, P, Ansari, M, Balduzzi, A, Dalassier, A, Dalle, J, Diaz, CH, Feuchtinger, T, Locatelli, F, Lucchini, G, Galimard, J, Vincent, MG, Handgretinger, R, Kleinschmidt, K, Lawitschka, A, Martinez, AP, Peters, C, Rocha, V, Ruggeri, A, Sedlacek, P, Svec, P, Toporski, J, Yesilipek, A, Achini-Gutzwiller, F, Snowden, J, Corbacioglu, S, Greco, R, Alexander, T, Badoglio, M, Labopin, M, Abinun, M, Apte, S, Arnold, R, Domenech, A, Brierley, C, Burman, J, Castilla-Llorente, C, Cooper, N, Daghia, G, Daikeler, T, del Papa, N, de Vries-Bouwstra, J, Farge, D, Finke, J, Hagglund, H, Hawkey, C, Henes, J, Hiepe, F, Jessop, H, Kiely, D, Kazmi, M, Kirgizov, K, Kramer, E, Mancardi, G, Marjanovic, Z, Martin, R, Martin, T, Ma, D, Moore, J, Miller, P, Muraro, P, Oliveira, M, Polushin, A, Onida, F, Simoes, B, Puyade, M, Resnick, I, Ricart, E, Rovira, M, Saccardi, R, Saif, M, Sakellari, I, Sharrack, B, Snarski, E, Scherer, H, Sossa, C, Withers, B, Wulffraat, N, Zaccara, E, Amrolia, P, Ansari, M, Balduzzi, A, Dalassier, A, Dalle, J, Diaz, C, Feuchtinger, T, Locatelli, F, Lucchini, G, Galimard, J, Vincent, M, Handgretinger, R, Kleinschmidt, K, Lawitschka, A, Martinez, A, Peters, C, Rocha, V, Ruggeri, A, Sedlacek, P, Svec, P, Toporski, J, and Yesilipek, A

Subjects
autoimmune diseases, haematopoietic stem cell transplantation, paediatric, ddc:610, paediatric, surgical procedures, operative, Settore MED/38 - PEDIATRIA GENERALE E SPECIALISTICA, haematopoietic stem cell transplantation, 610 Medizin, autoimmune diseases, autoimmune disease, Hematology
Abstract

Although modern clinical management strategies have improved the outcome of paediatric patients with severe autoimmune and inflammatory diseases over recent decades, a proportion will experience ongoing or recurrent/relapsing disease activity despite multiple therapies often leading to irreversible organ damage, and compromised quality of life, growth/development and long-term survival. Autologous and allogeneic haematopoietic stem cell transplantation (HSCT) have been used successfully to induce disease control and often apparent cure of severe treatment-refractory autoimmune diseases (ADs) in children. However, transplant-related outcomes are disease-dependent and long-term outcome data are limited in respect to efficacy and safety. Moreover, balancing risks of HSCT against AD prognosis with continually evolving non-transplant options is challenging. This review appraises published literature on HSCT strategies and outcomes in individual paediatric ADs. We also provide a summary of the European Society for Blood and Marrow Transplantation (EBMT) Registry, where 343 HSCT procedures (176 autologous and 167 allogeneic) have been reported in 326 children (

Published
2022

7. Kinetics of Cr3+ to Cr4+ ion valence transformations and intra-lattice cation exchange of Cr4+ in Cr,Ca:YAG ceramics used as laser gain and passive Q-switching media.

Author

Chaika, M. A., Tomala, R., Strek, W., Hreniak, D., Dluzewski, P., Morawiec, K., Mateychenko, P. V., Fedorov, A. G., Doroshenko, A. G., Parkhomenko, S. V., Lesniewska-Matys, K., Podniesinski, D., Kozłowska, A., Mancardi, G., and Vovk, O. M.

Subjects
YTTRIUM aluminum garnet, HEAT of reaction, TRANSPARENT ceramics, CERAMICS, ACTIVATION energy, IONS
Abstract

This paper focuses on the kinetics of Cr4+ formation in Cr,Ca:YAG ceramics prepared by solid-state reaction sintering. The kinetics of Cr4+ formation was studied by annealing of Cr,Ca:YAG ceramics in ambient air under different temperatures at different times, resulting in the transformation of Cr3+ to Cr4+. The activation energy (Ea) of Cr3+ oxidation determined by the Jander model was 2.7 ± 0.2 eV, which is in good correlation with the activation energy of innergrain oxygen diffusion in the YAG lattice. It is concluded that Cr3+ to Cr4+ transformation in YAG ceramics is limited by oxygen diffusion through the grain body. It was established that in Cr,Ca:YAG ceramics, the intralattice cation exchange, in which the Cr4+ ions exchange positions with the Al3+ ions, switching from "A" to "D" sites, is faster than Cr3+ to Cr4+ oxidation. In the temperature range of 900–1300 °C, the reaction enthalpy of Al3+/Cr4+ ion exchange between octahedral "A" and tetrahedral "D" lattice sites is close to zero, and this exchange ratio is thermodynamically driven by entropy. [ABSTRACT FROM AUTHOR]

Published
2019
Full Text
View/download PDF

9. Genetics of Hereditary Neuropathies

Author

Mancardi, G. L., Comi, Giancarlo, editor, Meldolesi, Jacopo, editor, Ecari, Ugo, editor, Filippi, Massimo, editor, Martino, Gianvito, editor, and Adorini, Luciano, editor

Published
1999
Full Text
View/download PDF

16. Strategia, Principi attuativi ed Analisi dell’impatto socio-economico del Percorso Ictus in Italia

Author

Bellantone, R, Moriconi, S, Gensini, G, Mennini, F, Bramanti, P, Miragliotta, F, Ferrara, N, Segreto, G, Landolfi, R, Alagna, B, Cisari, C, Cotroneo, E, Fiore, P, Francesco, F, Gangemi, M, Gemignani, V, Mancardi, G, Letizia Mauro, G, Mercuro, G, Micieli, G, Pistarini, C, Provinciali, L, Reale, N, Romeo, F, Rossini, P, Santalucia, P, Tavarnelli, M, Toni, D, and Tuccillo, R

Subjects
Settore SECS-P/03
Published
2021

18. Natalizumab therapy of multiple sclerosis: recommendations of the Multiple Sclerosis Study Group—Italian Neurological Society

Author

Ghezzi, A., Grimaldi, L. M. E., Marrosu, M. G., Pozzilli, C., Comi, G., Bertolotto, A., Trojano, M., Gallo, P., Capra, R., Centonze, D., Millefiorini, E., Sotgiu, S., Brescia Morra, V., Amato, M. P., Lugaresi, A., Mancardi, G., Caputo, D., Montanari, E., Provinciali, L., Durelli, L., Bergamaschi, R., Bellantonio, P., Tola, M. R., Cottone, S., Savettieri, G., Tedeschi, G., and MS-SIN Study Group

Published
2011
Full Text
View/download PDF

20. Postpartum relapses increase the risk of disability progression in multiple sclerosis: the role of disease modifying drugs

Author

Portaccio, Emilio, Ghezzi, Angelo, Hakiki, Bahia, Sturchio, Andrea, Martinelli, Vittorio, Moiola, Lucia, Patti, Francesco, Mancardi, Gian Luigi, Solaro, Claudio, Tola, Maria Rosaria, Pozzilli, Carlo, De Giglio, Laura, Totaro, Rocco, Lugaresi, Alessandra, De Luca, Giovanna, Paolicelli, Damiano, Marrosu, Maria Giovanna, Comi, Giancarlo, Trojano, Maria, Amato, Maria Pia, Amato, MP, Portaccio, E, Hakiki, B, Sturchio, A, Pastò, L, Giannini, M, Razzolini, L, Piscolla, E, Siracusa, G, Ghezzi, A, Rizzo, A, Zaffaroni, M, Martinelli, V, Radaelli, M, Moiola, L, Comi, G, Protti, A, Spreafico, C, Marazzi, R, Cavalla, P, Masera, S, Bergamaschi, R, Mancardi, G, Capello, E, Solaro, C, Tola, MR, Caniatti, L, Granella, F, Immovilli, P, Annunziata, P, De Santi, L, Plewnia, K, Guidi, L, Bartolozzi, ML, Mazzoni, M., Pozzilli, C, De Giglio, L, Totaro, R, Carolei, A, Rossi, M, Lugaresi, A, De Luca, G., Di Tommaso, V, Trojano, M, Paolicelli, D, Carrozzo, A, DʼOnghia, M, Marrosu, MG, Musu, L, Patti, F, Carmela, L, and Lo Fermo, S

Published
2014
Full Text
View/download PDF

21. AUTOLOGOUS HEMATOPOIETIC STEM CELL TRANSPLANTATION IN NEUROMYELITIS OPTICA: A RETROSPECTIVE STUDY OF THE EBMT AUTOIMMUNE DISEASES WORKING PARTY IN COLLABORATION WITH THE UNIVERSITY OF SAO PAOLO RIBEIRÃO PRETO BRAZIL: PH-P308

Author

Greco, R., Bondanza, A., Oliveira, M. C., Badoglio, M., Burman, J., Piehl, F., Hagglund, H., Krasulova, E., Simoes, Pinto B., Carlson, K., Pohlreich, D., Labopin, M., Saccardi, R., Comi, G., Mancardi, G. L., Bacigalupo, A., Ciceri, F., and Farge, D.

Published
2014

24. Autologous haematopoietic stem cell transplantation and other cellular therapy in multiple sclerosis and immune-mediated neurological diseases : updated guidelines and recommendations from the EBMT autoimmune diseases working party (ADWP) and the joint accreditation committee of EBMT and ISCT (JACIE)

Author

Sharrack, B., Saccardi, R., Alexander, T., Badoglio, M., Burman, J., Farge, D., Greco, R., Jessop, H., Kazmi, M., Kirgizov, K., Labopin, M., Mancardi, G., Martin, R., Moore, J., Muraro, P.A., Rovira, M., Sormani, M.P., and Snowden, J.A.

Subjects
surgical procedures, operative
Abstract

These updated EBMT guidelines review the clinical evidence, registry activity and mechanisms of action of haematopoietic stem cell transplantation (HSCT) in multiple sclerosis (MS) and other immune-mediated neurological diseases and provide recommendations for patient selection, transplant technique, follow-up and future development. The major focus is on autologous HSCT (aHSCT), used in MS for over two decades and currently the fastest growing indication for this treatment in Europe, with increasing evidence to support its use in highly active relapsing remitting MS failing to respond to disease modifying therapies. aHSCT may have a potential role in the treatment of the progressive forms of MS with a significant inflammatory component and other immune-mediated neurological diseases, including chronic inflammatory demyelinating polyneuropathy, neuromyelitis optica, myasthenia gravis and stiff person syndrome. Allogeneic HSCT should only be considered where potential risks are justified. Compared with other immunomodulatory treatments, HSCT is associated with greater short-term risks and requires close interspeciality collaboration between transplant physicians and neurologists with a special interest in these neurological conditions before, during and after treatment in accredited HSCT centres. Other experimental cell therapies are developmental for these diseases and patients should only be treated on clinical trials.

Published
2020

29. Consensus statement concerning cardiotoxicity occurring during haematopoietic stem cell transplantation in the treatment of autoimmune diseases, with special reference to systemic sclerosis and multiple sclerosis

Author

Saccardi, R, Tyndall, A, Coghlan, G, Denton, C, Edan, G, Emdin, M, Farge, D, Fassas, A, Finke, J, Furst, D, Lassus, M, Mancardi, G, Miniati, I, Mini, E, Pagliai, F, Passweg, J, Pignone, A, van Laar, J M, Bocelli-Tyndall, C, and Matucci-Cerinic, M

Published
2004
Full Text
View/download PDF

33. Hematopoietic stem cell transplantation for multiple sclerosis: A retrospective multicenter study

Author

Fassas, A.S., Passweg, J. R., Anagnostopoulos, A., Kazis, A., Kozak, T., Havrdova, E., Carreras, E., Graus, F., Kashyap, A., Openshaw, H., Schipperus, M., Deconinck, E., Mancardi, G., Marmont, A., Hansz, J., Rabusin, M., Zuazu Nagore, F. J., Besalduch, J., Dentamaro, T., Fouillard, L., Hertenstein, B., La Nasa, G., Musso, M., Papineschi, F., Rowe, J. M., Saccardi, R., Steck, A., Kappos, L., Gratwohl, A., Tyndall, A., and for the Autoimmune Disease Working Party of the EBMT (European Group for Blood and Marrow Transplantation)

Published
2002
Full Text
View/download PDF

35. Three years of experience: the Italian registry and safety data update

Author

Mancardi, G. L., Tedeschi, G., Amato, M. P., D’Alessandro, R., Drago, F., Milanese, C., Popoli, P., Rossi, P., Savettieri, G., Tola, M. R., Comi, G., Pozzilli, C., Bertolotto, A., Marrosu, M. G., Grimaldi, L. M. E., Laroni, A., Vanacore, N., Covezzoli, A., De Rosa, M., Piccinni, C., Montanaro, N., Periotto, L., Iommelli, R., Tomino, C., and Provinciali, L.

Published
2011
Full Text
View/download PDF

38. Leber's hereditary optic neuropathy (LHON/11778) with myoclonus: report of two cases. (Short Report)

Author

Carelli, V., Valentino, M. L., Liguori, R., Meletti, S., Vetrugno, R., Provini, F., Mancardi, G. L., Bandini, F., Baruzzi, A., and Montagna, P.

Subjects
Eye diseases -- Genetic aspects -- Complications and side effects, Optic nerve -- Diseases -- Genetic aspects, Peripheral nerve diseases -- Complications and side effects -- Genetic aspects, Health, Psychology and mental health, Diseases, Complications and side effects, Genetic aspects
Abstract

Abstract The previously unrecognised association of myoclonus in two patients with LHON with the 11778/ND4 pathogenic mutation is described. EEG failed to disclose epileptic figures, and a back averaging study [...]

Published
2001

43. Aggressive multiple sclerosis: a single‐centre, real‐world treatment experience with autologous haematopoietic stem cell transplantation and alemtuzumab

Author

Boffa, G., primary, Lapucci, C., additional, Sbragia, E., additional, Varaldo, R., additional, Raiola, A. M., additional, Currò, D., additional, Roccatagliata, L., additional, Capello, E., additional, Laroni, A., additional, Mikulska, M., additional, Gualandi, F., additional, Uccelli, A., additional, Angelucci, E., additional, Mancardi, G. L., additional, and Inglese, M., additional

Published
2020
Full Text
View/download PDF

44. The pharmacovigilance program on natalizumab in Italy: 2 years of experience

Author

Tedeschi, G., Amato, M. P., D’Alessandro, R., Drago, F., Milanese, C., Popoli, P., Rossi, P., Savettieri, G., Tola, M. R., Vanacore, N., Covezzoli, A., De Rosa, M., Comi, G., Pozzilli, Carlo, Bertolotto, Antonio, Marrosu, Maria Giovanna, Grimaldi, Luigi M. E., Piccinni, C., Montanaro, N., Periotto, Laura, Iommelli, Rosamaria, Addis, Antonio, Martini, Nello, Provinciali, L., and Mancardi, G. L.

Published
2009
Full Text
View/download PDF

46. Kinetics of Cr3+ to Cr4+ ion valence transformations and intra-lattice cation exchange of Cr4+ in Cr,Ca:YAG ceramics used as laser gain and passive Q-switching media

Author

Chaika, M. A., primary, Tomala, R., additional, Strek, W., additional, Hreniak, D., additional, Dluzewski, P., additional, Morawiec, K., additional, Mateychenko, P. V., additional, Fedorov, A. G., additional, Doroshenko, A. G., additional, Parkhomenko, S. V., additional, Lesniewska-Matys, K., additional, Podniesinski, D., additional, Kozłowska, A., additional, Mancardi, G., additional, and Vovk, O. M., additional

Published
2019
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results