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Erosive and oozing lesions of the nipple, especially when unilateral, should raise suspicion about malignant neoplasms. Herein we report a patient with typical clinical and histopathological features of erosive adenomatosis of the nipple (EAN). It is an uncommon, benign proliferative process of lactiferous ducts of the nipple. Clinically, EAN is characterized by erosion, serous discharge, edema, itching, and erythema of one of the nipples. Complete excision of the tumor yields excellent results. Although EAN is a rare disease, clinicians must be aware of this benign neoplasm in patients with erosive lesions of the nipple. The main concern is the need to rule out malignant proliferations in the differential diagnosis. Histology is the gold standard for diagnosis. The coexistence of nipple adenoma and breast cancer is well-reported in the literature. Thus, it is necessary to encourage patients with a history of EAN to maintain regular breast screening.

A 35-year-old man with Fitzpatrick skin type IV, born in Brazil, presented to the dermatology clinic with a growth on his left hip. The physical examination revealed a pedunculated erythematous–violaceous nodule with a hyperkeratotic surface. Histopathological examination confirmed a diagnosis of Kaposi sarcoma (KS), a low-grade angioproliferative tumor associated with human herpesvirus 8 (HHV-8). The patient was found to be HIV-positive and underwent treatment with highly active antiretroviral therapy (HAART), which resulted in a positive response and no disease relapse after one year. This case highlights the importance of recognizing the clinical and histological features of KS and the role of HHV-8 in its pathogenesis. [Extracted from the article]

This article discusses the case of a 44-year-old man who presented with recurrent crops of tender subcutaneous nodules. The patient had a history of fever, night sweats, weight loss, and other symptoms. After examination and testing, the diagnosis was determined to be erythema nodosum leprosum (ENL) complicating borderline lepromatous leprosy. The article provides information on leprosy, its classification, and the treatment options for ENL. The authors emphasize the importance of raising awareness about leprosy to avoid misdiagnosis and delayed treatment. [Extracted from the article]

An outbreak of monkeypox (MPX) has emerged across the globe.[[1]] In 2022, World Health Organization (WHO) reported more than 50,000 laboratory-confirmed cases until September.[1] Since early May 2022, many of these cases have been reported from countries without direct or immediate epidemiological links to West or Central Africa. A swab was performed at the base of the nipple lesion, which revealed the presence of MPX virus via real-time polymerase chain reaction (PCR). Human-to-human transmission of MPX can occur through large respiratory droplets, direct contact with the cutaneous or mucosal viral lesions/body fluids, and indirect contact with infected materials through clothing or infected linens.[[3], [5]] During the MPX outbreak of 2022, sexual activity was the most frequent transmission route, primarily among homosexual or bisexual men.[[5], [7]] Regarding the epidemiological history, the transmission route to the patient's partner remains to be elucidated. [Extracted from the article]

A 63-year-old woman presented at our emergency department with a disseminated dermatosis that developed after undergoing a cardiac catheterization procedure. Her past medical history included an end-stage renal disease undergoing hemodialysis. Clinical examination revealed erosions and hemorrhagic crusts located on her lips and along the arteriovenous fistula. Additionally, we observed five hyperpigmented macules on her left hand's dorsum and palm and multiple hypopigmented macules in the genital area. Upon medical record review, we discovered the occurrence of prior bullous eruptions following contrast administration. A fixed drug eruption (FDE) due to radiocontrast was diagnosed based on clinical history, clinical examination, eruption timeframe, and positive drug provocation test. Intravenous contrast media reactions can be immediate or delayed, with delayed hypersensitivity reactions (DHR) occurring one hour to seven days post-administration. DHRs often present as maculopapular rashes. FDEs are rare. Skin tests are used to identify culprit agents. Ideally, intradermal tests, with delayed readings, and patch tests are combined for optimal sensitivity. Despite lacking standardized protocols, premedication with corticosteroids may mitigate reaction severity., (© The Author(s) 2024. Published by Oxford University Press on behalf of British Association of Dermatologists. All rights reserved. For commercial re-use, please contact reprints@oup.com for reprints and translation rights for reprints. All other permissions can be obtained through our RightsLink service via the Permissions link on the article page on our site—for further information please contact journals.permissions@oup.com.)