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1. Successful implementation of a rater training program for medical students to evaluate simulated pediatric emergencies

Author

Mand, Nadine, Stibane, Tina, Sitter, Helmut, Maier, Rolf Felix, and Leonhardt, Andreas

Subjects
simulation, medical students, pediatric life support, Special aspects of education, LC8-6691, Medicine
Abstract

Introduction: Simulation-based training is increasingly used in pediatrics to teach technical skills, teamwork, and team communication, and to improve potential deficiencies in pediatric emergency care. Team performance must be observed, analyzed, and evaluated by trained raters. The structured training of medical students for the assessment of simulated pediatric emergencies has not yet been investigated. Methods: We developed a rater training program for medical students to assess guideline adherence, teamwork, and team communication in simulated pediatric emergencies. Interrater reliability was measured at each training stage using Kendall tau coefficients.Results: In 10 out of 15 pairs of raters interrater reliability was moderate to high (tau>0.4), whereas it was low in the remaining 5 pairs of raters.Discussion: The interrater reliability showed good agreement between medical students and expert raters at the end of the rater training program. Medical students can be successfully involved in the assessment of guideline adherence as well as teamwork and team communication in simulated pediatric emergencies.

Published
2023
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5. Management of Paediatric Cardiac Arrest due to Shockable Rhythm—A Simulation-Based Study at Children's Hospitals in a German Federal State.

Author

Mand, Nadine, Hoffmann, Marieke, Schwalb, Anja, Leonhardt, Andreas, Sassen, Martin, Stibane, Tina, Maier, Rolf Felix, and Donath, Carolin

Subjects
VENTRICULAR fibrillation treatment, NURSES, MEDICAL protocols, MEDICAL quality control, EDUCATIONAL outcomes, CHILDREN'S hospitals, DESCRIPTIVE statistics, RETROSPECTIVE studies, CHI-squared test, AMIODARONE, PEDIATRICS, SIMULATION methods in education, VENTRICULAR tachycardia, LIFE support systems in critical care, MEDICAL emergencies, RESEARCH, INTENSIVE care units, CARDIAC arrest, CARDIOPULMONARY resuscitation, PHYSICIANS, DATA analysis software, CONFIDENCE intervals, CHILDREN
Abstract

(1) Background: To improve the quality of emergency care for children, the Hessian Ministry for Social Affairs and Integration offered paediatric simulation-based training (SBT) for all children's hospitals in Hesse. We investigated the quality of paediatric life support (PLS) in simulated paediatric resuscitations before and after SBT. (2) Methods: In 2017, a standardised, high-fidelity, two-day in-house SBT was conducted in 11 children's hospitals. Before and after SBT, interprofessional teams participated in two study scenarios (PRE and POST) that followed the same clinical course of apnoea and cardiac arrest with a shockable rhythm. The quality of PLS was assessed using a performance evaluation checklist. (3) Results: 179 nurses and physicians participated, forming 47 PRE and 46 POST interprofessional teams. Ventilation was always initiated. Before SBT, chest compressions (CC) were initiated by 87%, and defibrillation by 60% of teams. After SBT, all teams initiated CC (p = 0.012), and 80% defibrillated the patient (p = 0.028). The time to initiate CC decreased significantly (PRE 123 ± 11 s, POST 76 ± 85 s, p = 0.030). (4) Conclusions: The quality of PLS in simulated paediatric cardiac arrests with shockable rhythm was poor in Hessian children's hospitals and improved significantly after SBT. To improve children's outcomes, SBT should be mandatory for paediatric staff and concentrate on the management of shockable rhythms. [ABSTRACT FROM AUTHOR]

Published
2024
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7. Breastfeeding Rates During the COVID-19 Pandemic in Germany: Data from the CRONOS Registry.

Author

Longardt, Ann Carolin, Zöllkau, Janine, Mand, Nadine, Wowretzko, Feline, Büchel, Johanna, Andresen, Kristin, Hoyer, Bimba Franziska, Kraft, Katrina, Pecks, Ulrich, Abou-Dakn, Michael, Adler, Jutta, Anders, Sophie-Isabelle, Backes, Clara, Banz-Jansen, Constanze, Berghäuser, Martin, Bohlmann, Michael, Brüggmann, Dörthe, Buchfink, Bettina, Dammer, Ulf, and Delius, Maria

Published
2024
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10. SARS-CoV-2 in Pregnancy, Birth and Puerperium. Guideline of the DGGG and DGPM (S2k-Level, AWMF Registry Number 015/092, March 2022)

Author

Pecks, Ulrich, additional, Agel, Lena, additional, Doubek, Klaus J., additional, Hagenbeck, Carsten, additional, Jennewein, Lukas, additional, von Kaisenberg, Constantin, additional, Kranke, Peter, additional, Leitner, Sabine, additional, Mand, Nadine, additional, Rüdiger, Mario, additional, Zöllkau, Janine, additional, Mingers, Nina, additional, Sitter, Magdalena, additional, and Louwen, Frank, additional

Published
2023
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12. SARS-CoV-2 infection during pregnancy

Author

Pecks, Ulrich, primary, Mand, Nadine, additional, Kolben, Thomas, additional, Rüdiger, Mario, additional, Oppelt, Peter, additional, Zöllkau, Janine, additional, and Dempfle, Astrid, additional

Published
2022
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14. Pediatric ICU Admissions After Adolescent Suicide Attempts During the Pandemic

Author

Bruns, Nora, primary, Willemsen, Lea, additional, Stang, Andreas, additional, Kowall, Bernd, additional, Holtkamp, Katharina, additional, Kamp, Oliver, additional, Dudda, Marcel, additional, Hey, Florian, additional, Hoffmann, Florian, additional, Blankenburg, Judith, additional, Eifinger, Frank, additional, Fuchs, Hans, additional, Haase, Roland, additional, Baier, Jan, additional, Andrée, Clemens, additional, Heldmann, Michael, additional, Maldera, Vanessa, additional, Potratz, Jenny, additional, Kurz, Daniel, additional, Mand, Nadine, additional, Doerfel, Claus, additional, Rothoeft, Tobias, additional, Schultz, Michel, additional, Ohlert, Manuel, additional, Silkenbäumer, Katrin, additional, Boesing, Thomas, additional, Indraswari, Fithri, additional, Niemann, Frank, additional, Jahn, Peter, additional, Merker, Michael, additional, Braun, Nicole, additional, Nunez, Francisco Brevis, additional, Engler, Matthias, additional, Heimann, Konrad, additional, Brasche, Milian, additional, Wolf, Gerhard, additional, Freymann, Holger, additional, Dercks, Martin, additional, Hoppenz, Marc, additional, Felderhoff-Müser, Ursula, additional, and Dohna-Schwake, Christian, additional

Published
2022
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15. Impact of the First COVID Lockdown on Accident- and Injury-Related Pediatric Intensive Care Admissions in Germany-A Multicenter Study

Author

Bruns, Nora, Willemsen, Lea Y., Holtkamp, Katharina, Kamp, Oliver, Dudda, Marcel, Kowall, Bernd, Stang, Andreas, Hey, Florian, Blankenburg, Judith, Sabir, Hemmen, Eifinger, Frank, Fuchs, Hans, Haase, Roland, Andree, Clemens, Heldmann, Michael, Potratz, Jenny, Kurz, Daniel, Schumann, Anja, Mueller-Knapp, Merle, Mand, Nadine, Doerfel, Claus, Dahlem, Peter, Rothoeft, Tobias, Ohlert, Manuel, Silkenbaeumer, Katrin, Dohle, Frank, Indraswari, Fithri, Niemann, Frank, Jahn, Peter, Merker, Michael, Braun, Nicole, Nunez, Francisco Brevis, Engler, Matthias, Heimann, Konrad, Wolf, Gerhard K., Wulf, Dominik, Hankel, Saskia, Freymann, Holger, Allgaier, Nicolas, Knirsch, Felix, Dercks, Martin, Reinhard, Julia, Hoppenz, Marc, Felderhoff-Mueser, Ursula, Dohna-Schwake, Christian, Bruns, Nora, Willemsen, Lea Y., Holtkamp, Katharina, Kamp, Oliver, Dudda, Marcel, Kowall, Bernd, Stang, Andreas, Hey, Florian, Blankenburg, Judith, Sabir, Hemmen, Eifinger, Frank, Fuchs, Hans, Haase, Roland, Andree, Clemens, Heldmann, Michael, Potratz, Jenny, Kurz, Daniel, Schumann, Anja, Mueller-Knapp, Merle, Mand, Nadine, Doerfel, Claus, Dahlem, Peter, Rothoeft, Tobias, Ohlert, Manuel, Silkenbaeumer, Katrin, Dohle, Frank, Indraswari, Fithri, Niemann, Frank, Jahn, Peter, Merker, Michael, Braun, Nicole, Nunez, Francisco Brevis, Engler, Matthias, Heimann, Konrad, Wolf, Gerhard K., Wulf, Dominik, Hankel, Saskia, Freymann, Holger, Allgaier, Nicolas, Knirsch, Felix, Dercks, Martin, Reinhard, Julia, Hoppenz, Marc, Felderhoff-Mueser, Ursula, and Dohna-Schwake, Christian

Abstract

Children's and adolescents' lives drastically changed during COVID lockdowns worldwide. To compare accident- and injury-related admissions to pediatric intensive care units (PICU) during the first German COVID lockdown with previous years, we conducted a retrospective multicenter study among 37 PICUs (21.5% of German PICU capacities). A total of 1444 admissions after accidents or injuries during the first lockdown period and matched periods of 2017-2019 were reported and standardized morbidity ratios (SMR) were calculated. Total PICU admissions due to accidents/injuries declined from an average of 366 to 346 (SMR 0.95 (CI 0.85-1.05)). Admissions with trauma increased from 196 to 212 (1.07 (0.93-1.23). Traffic accidents and school/kindergarten accidents decreased (0.77 (0.57-1.02 and 0.26 (0.05-0.75)), whereas household and leisure accidents increased (1.33 (1.06-1.66) and 1.34 (1.06-1.67)). Less neurosurgeries and more visceral surgeries were performed (0.69 (0.38-1.16) and 2.09 (1.19-3.39)). Non-accidental non-suicidal injuries declined (0.73 (0.42-1.17)). Suicide attempts increased in adolescent boys (1.38 (0.51-3.02)), but decreased in adolescent girls (0.56 (0.32-0.79)). In summary, changed trauma mechanisms entailed different surgeries compared to previous years. We found no evidence for an increase in child abuse cases requiring intensive care. The increase in suicide attempts among boys demands investigation.

Published
2022

16. Pediatric ICU Admissions After Adolescent Suicide Attempts During the Pandemic

Author

Bruns, Nora, Willemsen, Lea, Stang, Andreas, Kowall, Bernd, Holtkamp, Katharina, Kamp, Oliver, Dudda, Marcel, Hey, Florian, Hoffmann, Florian, Blankenburg, Judith, Eifinger, Frank, Fuchs, Hans, Haase, Roland, Baier, Jan, Andree, Clemens, Heldmann, Michael, Maldera, Vanessa, Potratz, Jenny, Kurz, Daniel, Mand, Nadine, Doerfel, Claus, Rothoeft, Tobias, Schultz, Michel, Ohlert, Manuel, Silkenbaeumer, Katrin, Boesing, Thomas, Indraswari, Fithri, Niemann, Frank, Jahn, Peter, Merker, Michael, Braun, Nicole, Nunez, Francisco Brevis, Engler, Matthias, Heimann, Konrad, Brasche, Milian, Wolf, Gerhard, Freymann, Holger, Dercks, Martin, Hoppenz, Marc, Felderhoff-Mueser, Ursula, Dohna-Schwake, Christian, Bruns, Nora, Willemsen, Lea, Stang, Andreas, Kowall, Bernd, Holtkamp, Katharina, Kamp, Oliver, Dudda, Marcel, Hey, Florian, Hoffmann, Florian, Blankenburg, Judith, Eifinger, Frank, Fuchs, Hans, Haase, Roland, Baier, Jan, Andree, Clemens, Heldmann, Michael, Maldera, Vanessa, Potratz, Jenny, Kurz, Daniel, Mand, Nadine, Doerfel, Claus, Rothoeft, Tobias, Schultz, Michel, Ohlert, Manuel, Silkenbaeumer, Katrin, Boesing, Thomas, Indraswari, Fithri, Niemann, Frank, Jahn, Peter, Merker, Michael, Braun, Nicole, Nunez, Francisco Brevis, Engler, Matthias, Heimann, Konrad, Brasche, Milian, Wolf, Gerhard, Freymann, Holger, Dercks, Martin, Hoppenz, Marc, Felderhoff-Mueser, Ursula, and Dohna-Schwake, Christian

Abstract

BACKGROUND AND OBJECTIVES: The worldwide severe acute respiratory syndrome coronavirus 2 pandemic challenges adolescents' mental health. In this study, we aim to compare the number of pediatric ICU (PICU) admissions after suicide attempts during the first German lockdown and one year later during a second, prolonged lockdown with prepandemic years. METHODS: A retrospective multicenter study was conducted among 27 German PICUs. Cases < 18 years admitted to the PICU because of accidents or injuries between March 16 and May 31 of 2017 to 2021 were identified based on International Classification of Diseases, 10th Revision codes (German modification) and patient data entered into a database. This study is a subset analysis on suicide attempts in adolescents aged 12 to 17.9 years. The Federal Statistics Office was queried for data on fatal suicides, which were available only for 2020 in adolescents aged 10 to 17.9 years. RESULTS: Total admissions and suicide attempts declined during the first lockdown in 2020 (standardized morbidity ratio 0.74 (95% confidence interval; 0.58-0.92) and 0.69 (0.43-1.04), respectively) and increased in 2021 (standardized morbidity ratio 2.14 [1.86-2.45] and 2.84 [2.29-3.49], respectively). Fatal suicide rates remained stable between 2017 to 2019 and 2020 (1.57 vs 1.48 per 100 000 adolescent years) with monthly numbers showing no clear trend during the course of 2020. CONCLUSIONS: This study shows a strong increase in serious suicide attempts among adolescents during the course of the pandemic in Germany. More research is needed to understand the relation between pandemic prevention measures and suicidal ideation to help implement mental health support for adolescents.

Published
2022

20. Antibody Response and Maternofetal Antibody Transfer in SARS-CoV-2-Positive Pregnant Women: A Multicenter Observational Study

Author

Enengl, Sabine, additional, Pecks, Ulrich, additional, Oppelt, Peter, additional, Stelzl, Patrick, additional, Trautner, Philip Sebastian, additional, Shebl, Omar, additional, Lamprecht, Bernd, additional, Longardt, Ann Carolin, additional, Eckmann-Scholz, Christel, additional, Keil, Corinna, additional, Mand, Nadine, additional, von Kaisenberg, Constantin Sylvius, additional, Jegen, Magdalena, additional, Doppler, Stefan, additional, and Lastinger, Julia, additional

Published
2022
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22. Impact of the First COVID Lockdown on Accident- and Injury-Related Pediatric Intensive Care Admissions in Germany—A Multicenter Study

Author

Bruns, Nora, primary, Willemsen, Lea Y., additional, Holtkamp, Katharina, additional, Kamp, Oliver, additional, Dudda, Marcel, additional, Kowall, Bernd, additional, Stang, Andreas, additional, Hey, Florian, additional, Blankenburg, Judith, additional, Sabir, Hemmen, additional, Eifinger, Frank, additional, Fuchs, Hans, additional, Haase, Roland, additional, Andrée, Clemens, additional, Heldmann, Michael, additional, Potratz, Jenny, additional, Kurz, Daniel, additional, Schumann, Anja, additional, Müller-Knapp, Merle, additional, Mand, Nadine, additional, Doerfel, Claus, additional, Dahlem, Peter, additional, Rothoeft, Tobias, additional, Ohlert, Manuel, additional, Silkenbäumer, Katrin, additional, Dohle, Frank, additional, Indraswari, Fithri, additional, Niemann, Frank, additional, Jahn, Peter, additional, Merker, Michael, additional, Braun, Nicole, additional, Brevis Nunez, Francisco Brevis, additional, Engler, Matthias, additional, Heimann, Konrad, additional, Wolf, Gerhard K., additional, Wulf, Dominik, additional, Hankel, Saskia, additional, Freymann, Holger, additional, Allgaier, Nicolas, additional, Knirsch, Felix, additional, Dercks, Martin, additional, Reinhard, Julia, additional, Hoppenz, Marc, additional, Felderhoff-Müser, Ursula, additional, and Dohna-Schwake, Christian, additional

Published
2022
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24. Trends in accident-related admissions to pediatric intensive care units during the first COVID-19 lockdown in Germany

Author

Bruns, Nora, primary, Willemsen, Lea, additional, Holtkamp, Katharina, additional, Kamp, Oliver, additional, Dudda, Marcel, additional, Kowall, Bernd, additional, Stang, Andreas, additional, Hey, Florian, additional, Blankenburg, Judith, additional, Hemmen, Sabir, additional, Eifinger, Frank, additional, Fuchs, Hans, additional, Haase, Roland, additional, Andrée, Clemens, additional, Heldmann, Michael, additional, Potratz, Jenny, additional, Kurz, Daniel, additional, Schumann, Anja, additional, Müller-Knapp, Merle, additional, Mand, Nadine, additional, Doerfel, Claus, additional, Dahlem, Peter, additional, Rothoeft, Tobias, additional, Ohlert, Manuel, additional, Silkenbäumer, Katrin, additional, Dohle, Frank, additional, Indraswari, Fithri, additional, Niemann, Frank, additional, Jahn, Peter, additional, Merker, Michael, additional, Braun, Nicole, additional, Nunez, Francisco Brevis, additional, Engler, Matthias, additional, Heimann, Konrad, additional, Wolf, Gerhard, additional, Wulf, Dominik, additional, Hollborn, Claudia, additional, Freymann, Holger, additional, Allgaier, Nicolas, additional, Knirsch, Felix, additional, Dercks, Martin, additional, Reinhard, Julia, additional, Hoppenz, Marc, additional, Felderhoff-Müser, Ursula, additional, and Dohna-Schwake, Christian, additional

Published
2021
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27. Teamarbeit in pädiatrischen Notfallsituationen

Author

Mand, Nadine, Schöttler, Michelle, Maier, Rolf F., Stibane, Tina, Sitter, Helmut, Grosch, Stephan, and Leonhardt, Andreas

Subjects
ddc: 610, 610 Medical sciences, Medicine
Abstract

Einleitung: Pädiatrische Notfälle sind seltene Ereignisse, für die im klinischen Alltag für die Mehrzahl des pflegerischen und ärztlichen Personals keine Routine erreicht werden kann. In Simulationstrainings können sie wiederholt trainiert werden. Neben der Verbesserung[zum vollständigen Text gelangen Sie über die oben angegebene URL], Gemeinsame Jahrestagung der Gesellschaft für Medizinische Ausbildung (GMA), des Arbeitskreises zur Weiterentwicklung der Lehre in der Zahnmedizin (AKWLZ) und der Chirurgischen Arbeitsgemeinschaft Lehre (CAL)

Published
2019
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28. Pädiatrisches Notfallmanagement an hessischen Kinderkliniken

Author

Hoffmann, Marieke, Mand, Nadine, and Stibane, Tina

Subjects
ddc: 610, 610 Medical sciences, Medicine
Abstract

Hintergrund: Pädiatrische Notfälle und insbesondere Reanimationen sind äußerst selten, weshalb die Mehrzahl der Pfleger und Ärzte keine Routine erreichen können. Durch Simulationstrainings kann eben diese durch wiederholte Übungen in geschütztem Umfeld trainiert[zum vollständigen Text gelangen Sie über die oben angegebene URL], 14. Internationales SkillsLab Symposium 2019

Published
2019

32. Influence of SARS-CoV-2 variants of concern and maternal vaccination status on neonatal outcome.

Author

Mand N, Pecks U, Hutten M, Maier RF, and Rüdiger M

Subjects
Adult, Female, Humans, Infant, Newborn, Pregnancy, Premature Birth epidemiology, Registries, SARS-CoV-2 genetics, COVID-19 prevention & control, COVID-19 immunology, COVID-19 epidemiology, COVID-19 Vaccines administration & dosage, COVID-19 Vaccines adverse effects, Pregnancy Complications, Infectious prevention & control, Pregnancy Complications, Infectious virology, Pregnancy Outcome epidemiology, Vaccination
Abstract

SARS-CoV-2 infection during pregnancy can adversely affect maternal and neonatal health, although risks vary depending on the variant of concern (VOC). Omicron, although highly infectious, causes fewer maternal and neonatal complications than earlier VOC, so vaccination may be considered unnecessary in planned pregnancy. Using data from the CRONOS registry, we compared pregnancy outcomes according to VOC and vaccination status. We found that vaccination during pregnancy reduced preterm birth rates compared with unvaccinated or vaccinated women with Omicron infection, without increasing severe neonatal outcomes. Given the risks associated with preterm birth, the study consistently supports vaccination recommendations for women planning pregnancy., Competing Interests: Competing interests: None declared., (© Author(s) (or their employer(s)) 2025. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ Group.)

Published
2025
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33. [The Complexity of SARS-CoV-2 Infection in the Clinical Setting of Obstetrics - Discussion Based on a Case Study].

Author

Möginger M, Mand N, Schoner K, Seipelt M, Schulze M, Köhler S, Axt-Fliedner R, and Keil CN

Subjects
Humans, SARS-CoV-2, COVID-19 diagnosis, COVID-19 therapy, Posterior Leukoencephalopathy Syndrome
Abstract

Since the beginning of the pandemic, SARS-CoV-2 infection has dominated clinical practice. In the treatment of high-risk populations, there has long been uncertainty about the extent and consequences of infection. This high-risk population includes pregnant patients. The establishment of clinical registry studies was able to contribute an assessment of the pandemic situation for this collective within a very short time and with enormous effort. Based on a clinical case, the following report describes the association between SARS-CoV-2 infection of a pregnant patient with clinical signs of preeclampsia to the development of posterior reversible encephalopathy syndrome (PRES). Based on the case, the differential diagnostic workup between fulminant course of infection and preeclampsia is presented. The article presents the current data on the occurrence of PRES in pregnancy in the context of SARS-CoV-2 infection and addresses possible differential diagnoses. Interdisciplinary care of the patient allows an overview of aspects of each specialty to be presented., Competing Interests: Die Autorinnen/Autoren geben an, dass kein Interessenkonflikt besteht., (Thieme. All rights reserved.)

Published
2022
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