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Ocular surface inflammation due to allergy and blepharitis can lead to corneal complications and visual impairment. The aim of this study is to evaluate the efficacy of a cyclosporin 0.1% topical treatment achieving steroid-sparing. Eighty pediatric patients with moderate and severe vernal and blepharitis-related keratoconjunctivitis were included. Symptoms (photosensitivity, itching, discharge, tearing), signs (corneal fluorescein staining, papillary hypertrophy) and patients' subjective assessment were evaluated during a 6-month follow-up. At the follow-up, all patients treated with topical cyclosporin showed a significant improvement in all subjective symptoms and objective signs (p < 0.001). The total number of courses of rescue steroids courses decreased from 3.71 ± 1.72 to 0.25 ± 0.49 at month 3 and to 0.13 ± 0.38 dropping bottle at month 6 (p < 0.001 at both time points). The 96.1% of the allergic cohort and 96.4% of the blepharitis cohort experienced a satisfactory good or rapid and good effect during the 6-month follow-up. The probability of needing rescue corticosteroids increased with an odds ratio of 1.98, (95% CI: 1.19–3.28, p = 0.008) for each unit increase in Oxford score when analysing the whole cohort. Topical cyclosporin seems to be very effective reducing the number of recurrences of corneal involvement and the need for steroid treatment. [ABSTRACT FROM AUTHOR]

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Összefoglaló. Bevezetés: Csecsemőkorban a könnyezés gyakori oka a könnycsatorna veleszületett elzáródása, mely az esetek nagy részében 1 éves korra spontán oldódik. Célkitűzés: Retrospektív tanulmányunk célja a monocanalicularis szilikonsztent (Masterka®) implantációjával kapcsolatos eredményeink bemutatása. Módszer: 2015. január 1. és 2020. január 30. között monocanalicularis szilikonsztent implantációján átesett gyermekek adatait dolgoztuk fel. Bevonási kritériumként szerepelt a legalább 6 hónapja fennálló, konzervatív kezelésre nem szűnő könnyezés és emiatt előzetesen elvégzett szondázás, mely után a panaszok kiújultak. Kizárási kritérium volt a csontosan elzárt ductus nasolacrimalis és a hibás szemhéjállás. A műtét hatékonyságát a szilikonsztent eltávolítását követő legalább 2 hónap panaszmentességgel definiáltuk. Eredmények: 25 gyermek (10 lány [40%] és 15 fiú [60%]) összesen 30 szemén végeztünk szilikonsztent-beültetést. Az átlagéletkor 4,92 ± 3,03 év (1,5-12 év, n = 25) volt. Minden páciens a születése óta könnyezett. A műtét előtt váladékképződést 20 (66,67%, n = 30), krónikus szemhéj- és kötőhártya-gyulladást 10 (33,33%, n = 30) esetben észleltünk. Tompalátást, jelentős astigmiát nem találtunk. A sztentet átlagosan 3,5 ± 1,0 (n = 30) hónap után távolítottuk el. A műtétet követően 1 héttel 24 (80%, n = 30), 3 hónappal 28 (93,33%, n = 30) és 6 hónappal 24 (88,89%, n = 27) szem volt tünetmentes. Következtetés: A Masterka® implantációja egyszerűen kivitelezhető, kifejezetten hatékony módszer lehet az 1 évnél idősebb gyermekek veleszületett könnycsatorna-szűkületének megoldására, különösen olyan esetekben, amikor a korábbi szondázás nem vezetett eredményre, valamint hosszabb szakaszon észlelünk szűkületet. Ez utóbbi esetekben megfontolandó lenne a primer szilikonsztent-implantáció is. Orv Hetil. 2020; 161(48): 2037-2042., Introduction: Congenital nasolacrimal duct obstruction is a common cause of epiphora in infants. In most cases, spontaneous resolution occurs by 1 year of age., Objective: Retrospective evaluation of clinical outcomes of monocanalicular lacrimal duct stent implantation (Masterka®)., Method: Data of patients undergoing monocanalicular silicone stent implantation between 1st January 2015 and 30th January 2020 were evaluated. Inclusion criteria were resistant tearing to conservative therapy which had been persisting at least for 6 months, and previous probing did not resolve the symptoms. Exclusion criteria were associated bony obstruction or eyelid malposition. Treatment success was defined as complete resolution of epiphora at least two months after the procedure., Results: Implantation was performed on 30 eyes of 25 children (10 females [40%] and 15 males [60%]). The mean age was 4.92 ± 3.03 years (1.5-12 years, n = 25). Epiphora was a persistent symptom in every patient since birth. Preoperatively, discharge was observed in 20 (66.6%, n = 30) patients, while chronic blepharitis and conjunctivitis occurred in 10 (33.33%, n = 30) children. Amblyopia or significant astigmatism was not observed in any case. Stent was removed after 3.5 ± 1.0 (n = 30) months. At one week postoperatively 24 (80%, n = 30), at 3 months 28 (93.33%, n = 30) and at 6 months 24 (88.89%, n = 27) eyes were asymptomatic., Conclusion: Implantation of monocanalicular silicone stent is effective and easy-to-perform. It can resolve congenital tear duct stenosis, especially where previous probing was not successful and where stenosis is longer or occurs in several localizations. In the latter cases, primary stent implantation should be considered. Orv Hetil. 2020; 161(48): 2037-2042.

Introduction: Idiopathic strabismus sursoadductorius is characterized by an overaction of the inferior oblique (IO) muscle, with elevation of the eye in adduction. This can result in chronic headache, eye pain, diplopia and abnormal head posture. Aim: Presentation of clinical results after graded recession of inferior oblique overaction (IOOA) in strabismus sursoadductorius. Method: During a period of 6 years (2012-2017) we performed a dosed transposition of IO muscle in 53 patients in the Department of Ophthalmology of the Semmelweis University and analyzed the clinical results retrospectively. The mean age was 12.8, min-max: 2-51 years. The transposition of the muscle (8 mm, 10 mm or maximal) was performed because of IOOA and was planned depending on the vertical deviation (VD) in maximal adduction. In case of maximal transposition, the insertion of IO was placed under the lateral part of the lower rectus muscle. We evaluated the squint angle in five positions of gaze preoperatively and postoperative 1 week, 1 month and 3-6 months. We examined best corrected visual acuity, binocular vision and complications after surgery. Results: Postoperatively 25 patients had acceptable stereopsis (Titmus 5). Visual acuity remained stable after surgery in all cases. The VD measured in maximal adduction changed with a decrease of 7.5° when 8 mm transposition was performed, and changed with a decrease to 12°, when maximal recession was performed. The mean reduction of VD was 17.8 prism dioptres (PD) after 1 week (p<0.01), 20.5 PD after 1 month and remained stable during a follow-up of 3-6 months. Conclusion: Graded recession of inferior oblique muscle is a suitable proposed procedure in patients with marked strabismus sursoadductorius. The rates of functional under- or overcorrection or other complications are low. Orv Hetil. 2019; 160(27): 1064-1069.