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16 results on '"Mangoni, Lorenza"'

4. Determinants of All-Cause Mortality in Different Age Groups in Patients With Severe Systolic Left Ventricular Dysfunction Receiving an Implantable Cardioverter Defibrillator (from the Italian ClinicalService Multicenter Observational Project)

Author

Fumagalli, Stefano, Gasparini, Maurizio, Landolina, Maurizio, Lunati, Maurizio, Boriani, Giuseppe, Proclemer, Alessandro, Santini, Massimo, Mangoni, Lorenza, Padeletti, Margherita, Marchionni, Niccolò, and Padeletti, Luigi

Published
2014
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5. Low-dose dobutamine test associated with interventricular dyssynchrony: A useful tool to identify cardiac resynchronization therapy responders: Data from the LOw dose DObutamine stress-echo test in Cardiac Resynchronization Therapy (LODO-CRT) phase 2 study

Author

Gasparini, Maurizio, Muto, Carmine, Iacopino, Saverio, Zanon, Francesco, Dicandia, Cosimo, Distefano, Giuseppe, Favale, Stefano, Peraldo Neja, Carlo, Bragato, Renato, Davinelli, Mario, Mangoni, Lorenza, and Denaro, Alessandra

Published
2012
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7. Ventricular rate monitoring as a tool to predict and prevent atrial fibrillation-related inappropriate shocks in heart failure patients treated with cardiac resynchronisation therapy defibrillators

Author

Ricci, Renato Pietro, Pignalberi, Carlo, Landolina, Maurizio, Santini, Massimo, Lunati, Maurizio, Boriani, Giuseppe, Proclemer, Alessandro, Facchin, Domenico, Catanzariti, Domenico, Morani, Giovanni, Gulizia, Michele, Mangoni, Lorenza, Grammatico, Andrea, and Gasparini, Maurizio

Published
2014
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8. Atrioventricular junction ablation in patients with atrial fibrillation treated with cardiac resynchronization therapy:Positive impact on ventricular arrhythmias, implantable cardioverter-defibrillator therapies and hospitalizations

Author

Gasparini, Maurizio, Kloppe, Axel, Lunati, Maurizio, Anselme, Frédéric, Landolina, Maurizio, Martinez-Ferrer, Jose Bautista, Proclemer, Alessandro, Morani, Giovanni, Biffi, Mauro, Ricci, Renato, Rordorf, Roberto, Mangoni, Lorenza, Manotta, Laura, Grammatico, Andrea, Leyva, Francisco, and Boriani, Giuseppe

Abstract

Aims: We sought to determine whether atrioventricular junction ablation (AVJA) in patients with cardiac resynchronization therapy (CRT) implantable cardioverter-defibrillator (ICD) and with permanent atrial fibrillation (AF) has a positive impact on ICD shocks and hospitalizations compared with rate-slowing drugs. Methods and results: This is a pooled analysis of data from 179 international centres participating in two randomized trials and one prospective observational research. The co-primary endpoints were all-cause ICD shocks and all-cause hospitalizations. Out of 3358 CRT-ICD patients (2720 male, 66.6years), 2694 (80%) were in sinus rhythm (SR) and 664 (20%) had permanent AF-262 (8%) treated with AVJA (AF+AVJA) and 402 (12%) treated with rate-slowing drugs (AF+Drugs). Median follow-up was 18months. The mean (95% confidence intervals) annual rate of all-cause ICD shocks per 100 patient years was 8.0 (5.3-11.9) in AF+AVJA, 43.6 (37.7-50.4) in AF+Drugs, and 34.4 (32.5-36.5) in SR patients, resulting in incidence rate ratio (IRR) reductions of 0.18 (0.10-0.32) for AF+AVJA vs. AF+Drugs (P

Published
2018

9. Atrioventricular junction ablation in patients with atrial fibrillation treated with cardiac resynchronization therapy: positive impact on ventricular arrhythmias, implantable cardioverter-defibrillator therapies and hospitalizations

Author

Gasparini, Maurizio, primary, Kloppe, Axel, additional, Lunati, Maurizio, additional, Anselme, Frédéric, additional, Landolina, Maurizio, additional, Martinez-Ferrer, Jose Bautista, additional, Proclemer, Alessandro, additional, Morani, Giovanni, additional, Biffi, Mauro, additional, Ricci, Renato, additional, Rordorf, Roberto, additional, Mangoni, Lorenza, additional, Manotta, Laura, additional, Grammatico, Andrea, additional, Leyva, Francisco, additional, and Boriani, Giuseppe, additional

Published
2017
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10. Different impact of long-detection interval and anti-tachycardia pacing in reducing unnecessary shocks: data from the ADVANCE III trial

Author

Arenal, Angel, primary, Proclemer, Alessandro, additional, Kloppe, Axel, additional, Lunati, Maurizio, additional, Martìnez Ferrer, José Bautista, additional, Hersi, Ahmad, additional, Gulaj, Marcin, additional, Wijffels, Maurits C.E.F., additional, Santi, Elisabetta, additional, Manotta, Laura, additional, Mangoni, Lorenza, additional, and Gasparini, Maurizio, additional

Published
2016
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11. Atrioventricular junction ablation in patients with atrial fibrillation treated with cardiac resynchronization therapy: positive impact on ventricular arrhythmias, implantable cardioverter-defibrillator therapies and hospitalizations.

Author

Gasparini, Maurizio, Kloppe, Axel, Lunati, Maurizio, Anselme, Frédéric, Landolina, Maurizio, Martinez‐Ferrer, Jose Bautista, Proclemer, Alessandro, Morani, Giovanni, Biffi, Mauro, Ricci, Renato, Rordorf, Roberto, Mangoni, Lorenza, Manotta, Laura, Grammatico, Andrea, Leyva, Francisco, Boriani, Giuseppe, and Martinez-Ferrer, Jose Bautista

Subjects
ABLATION techniques, CARDIAC pacing, HEART failure, ATRIAL fibrillation, MYOCARDIAL infarction, ATRIAL fibrillation treatment, VENTRICULAR tachycardia, ATRIOVENTRICULAR node, CATHETER ablation, HEART beat, HOSPITAL care, IMPLANTABLE cardioverter-defibrillators, SECONDARY analysis, TREATMENT effectiveness, SURGERY, THERAPEUTICS
Abstract

Aims: We sought to determine whether atrioventricular junction ablation (AVJA) in patients with cardiac resynchronization therapy (CRT) implantable cardioverter-defibrillator (ICD) and with permanent atrial fibrillation (AF) has a positive impact on ICD shocks and hospitalizations compared with rate-slowing drugs.Methods and Results: This is a pooled analysis of data from 179 international centres participating in two randomized trials and one prospective observational research. The co-primary endpoints were all-cause ICD shocks and all-cause hospitalizations. Out of 3358 CRT-ICD patients (2720 male, 66.6 years), 2694 (80%) were in sinus rhythm (SR) and 664 (20%) had permanent AF-262 (8%) treated with AVJA (AF + AVJA) and 402 (12%) treated with rate-slowing drugs (AF + Drugs). Median follow-up was 18 months. The mean (95% confidence intervals) annual rate of all-cause ICD shocks per 100 patient years was 8.0 (5.3-11.9) in AF + AVJA, 43.6 (37.7-50.4) in AF + Drugs, and 34.4 (32.5-36.5) in SR patients, resulting in incidence rate ratio (IRR) reductions of 0.18 (0.10-0.32) for AF + AVJA vs. AF + Drugs (P < 0.001) and 0.48 (0.35-0.66) for AF + AVJA vs. SR (P < 0.001). These reductions were driven by significant reductions in both appropriate ICD shocks [IRR 0.23 (0.13-0.40), P < 0.001, vs. AF + Drugs] and inappropriate ICD shocks [IRR 0.09 (0.04-0.21), P < 0.001, vs. AF + Drugs]. Annual rate of all-cause hospitalizations was significantly lower in AF + AVJA vs. AF + Drugs [IRR 0.57 (0.41-0.79), P < 0.001] and SR [IRR 0.85 (073-0.98), P = 0.027].Conclusion: In AF patients treated with CRT, AVJA results in a lower incidence and burden of all-cause, appropriate and inappropriate ICD shocks, as well as to fewer all-cause and heart failure hospitalizations.Clinical Trial Registration: NCT00147290, NCT00617175, NCT01007474. [ABSTRACT FROM AUTHOR]

Published
2018
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12. Association between ventricular pacing and persistent atrial fibrillation in patients indicated to elective pacemaker replacement: Results of the Prefer for Elective Replacement MVP (PreFER MVP) randomized study

Author

UCL - (MGD) Service de cardiologie, UCL - SSS/IREC/CARD - Pôle de recherche cardiovasculaire, Ricci, Renato P, Botto, Giovanni Luca, Bénézet, Juan M, Nielsen, Jens Cosedis, De Roy , Luc, Piot, Olivier, Quesada, Aurelio, Quaglione, Raffaele, Vaccari, Diego, Mangoni, Lorenza, Grammatico, Andrea, Kozák, Milan, PreFER MVP Investigators, UCL - (MGD) Service de cardiologie, UCL - SSS/IREC/CARD - Pôle de recherche cardiovasculaire, Ricci, Renato P, Botto, Giovanni Luca, Bénézet, Juan M, Nielsen, Jens Cosedis, De Roy , Luc, Piot, Olivier, Quesada, Aurelio, Quaglione, Raffaele, Vaccari, Diego, Mangoni, Lorenza, Grammatico, Andrea, Kozák, Milan, and PreFER MVP Investigators

Abstract

Background Pacing in the right ventricle can cause a variety of detrimental effects, including atrial tachyarrhythmias (atrial tachycardia [AT]/atrial fibrillation [AF]). Objective The purpose of this study was to evaluate the incidence and predictors of persistent AT/AF in patients with long-term exposure to ventricular pacing. Methods In a multicenter international trial, 605 patients (age 75 ± 11 years, 240 women) referred for replacement of an implanted pacemaker or implantable cardioverter-defibrillator (ICD), with a history of high-percentage (>40%) ventricular pacing, were randomly allocated to standard dual-chamber pacing or managed ventricular pacing (MVP), a pacing modality that minimizes ventricular pacing. The main end-point of this secondary analysis of the PreFER MVP randomized study was persistent AT/AF, defined as ≥7 consecutive days with AT/AF or AT/AF interrupted by atrial cardioversion or AT/AF present during 2 consecutive follow-up visits. Results Persistent AT/AF was observed in 71 patients (11.7%) after 2 years of follow-up. At multivariable Cox regression analysis, prior AT/AF (hazard ratio [HR] 2.85, 95% confidence interval [CI] 1.20-6.22, P =.017) and ventricular pacing percentage, estimated in the first 3 months, ≥10% (HR 3.24, 95% 95% CI 1.13-9.31, P =.029) were independent predictors for persistent AT/AF. MVP was associated with persistent AT/AF risk (HR 3.41, 95% 95% CI 1.10-10.6, P =.024) in the subgroup of patients with baseline long PR interval (PR >230 ms) but not in the whole population. Conclusion In pacemaker and ICD replacement patients, a high percentage of ventricular pacing is associated with higher risk of persistent AT/AF. Use of algorithms that minimize right ventricular pacing may benefit patients with normal spontaneous AV conduction but should be evaluated with caution in patients with long PR interval

Published
2015

14. Efficacy of Long Detection Interval Implantable Cardioverter-Defibrillator Settings in Secondary Prevention Population

Author

Kloppe, Axel, primary, Proclemer, Alessandro, additional, Arenal, Angel, additional, Lunati, Maurizio, additional, Martìnez Ferrer, José Bautista, additional, Hersi, Ahmad, additional, Gulaj, Marcin, additional, Wijffels, Maurits C.E.F., additional, Santi, Elisabetta, additional, Manotta, Laura, additional, Mangoni, Lorenza, additional, and Gasparini, Maurizio, additional

Published
2014
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15. Acute kidney injury after transcatheter aortic valve implantation with self-expanding CoreValve prosthesis: results from a large multicentre Italian research project

Author

Barbanti, Marco, primary, Latib, Azeem, additional, Sgroi, Carmelo, additional, Fiorina, Claudia, additional, De Carlo, Marco, additional, Bedogni, Francesco, additional, De Marco, Federico, additional, Ettori, Federica, additional, Petronio, Anna Sonia, additional, Colombo, Antonio, additional, Testa, Luca, additional, Klugmann, Silvio, additional, Poli, Arnaldo, additional, Maffeo, Diego, additional, Maisano, Francesco, additional, Aruta, Patrizia, additional, Gulino, Simona, additional, Giarratana, Alessandra, additional, Patanè, Martina, additional, Cannata, Stefano, additional, Immè, Sebastiano, additional, Mangoni, Lorenza, additional, Rossi, Agnese, additional, and Tamburino, Corrado, additional

Published
2014
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16. Comparison Between Sensor-Augmented Insulin Therapy with Continuous Subcutaneous Insulin Infusion or Multiple Daily Injections in Everyday Life: 3-Day Analysis of Glucose Patterns and Sensor Accuracy in Children

Author

Zucchini, Stefano, primary, Scipione, Mirella, additional, Balsamo, Claudia, additional, Maltoni, Giulio, additional, Rollo, Alessandra, additional, Molinari, Emanuela, additional, Mangoni, Lorenza, additional, and Cicognani, Alessandro, additional

Published
2011
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