Search

In this paper, we employ the techniques in [C. Cavaterra, S. Dipierro, Z. Gao and E. Valdinoci, Global gradient estimates for a general type of nonlinear parabolic equations, J. Geom. Anal. 32 2022, 2, Paper No. 65] and the approach in [H. T. Dung and N. T. Dung, Sharp gradient estimates for a heat equation in Riemannian manifolds, Proc. Amer. Math. Soc. 147 2019, 12, 5329–5338] to derive sharp gradient estimates for a positive solution to the heat equation u t = Δ ⁢ u + a ⁢ u ⁢ log ⁡ u in a complete noncompact Riemannian manifold (where a is a real constant). This is an extension of the gradient estimates of Dung and Dung. [ABSTRACT FROM AUTHOR]

Purpose: The purpose of this study was to evaluate the safety and efficacy of mechanical thrombectomy with a direct aspiration first-pass technique (ADAPT) using large-bore catheters in patients with acute ischemic stroke due to large vessel occlusion (LVO) in a hospital in Vietnam., Methods: This was a retrospective review of patients with acute ischemic stroke due to LVO who were diagnosed and underwent mechanical thrombectomy using ADAPT with large-bore catheters at Bach Mai Hospital from January 2017 to June 2018., Results: Seventy-three patients (47.9% female; age: 61.29 ± 14.49 years) met study criteria. The average procedure duration was 45.09 ± 38.26 min. Successful recanalization post-ADAPT (thrombolysis in cerebral infarction 2b-3) was achieved in 72.6% (53/73) of patients. Good functional outcome (Modified Rankin Scale 0-2) at 3 months was achieved in 50.7% (37/73), with poor functional outcome in 24.7% (18/73). The 90-day mortality rate was 24.7% (18/73). The hemorrhagic transformation rate was 31.6%, in which 19.2% were symptomatic. Vessel perforation occurred in 5.5% (4/73) of patients but in all cases was associated with the guidewire and not the reperfusion catheter. Vessel dissection occurred in 1.4% (1/73) and vasospasm in 5.5% (4/73) of patients., Conclusion: Mechanical thrombectomy using ADAPT with large-bore catheters for acute ischemic stroke due to LVO is a method that yielded good results in recanalization and clinical recovery in a Vietnamese patient population., Competing Interests: There are no conflicts of interest., (Copyright: © 2020 Asian Journal of Neurosurgery.)