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Ramya Manoharan,1 Chythra Somanathan Nair,1 Nermin Eissa,2 Hao Cheng,3 Pengliang Ge,4 Maozhi Ren,3 Abdul Jaleel1 1Department of Integrative Agriculture, College of Agriculture and Veterinary Medicine, United Arab Emirates University, Al Ain, United Arab Emirates; 2Department of Biomedical Sciences, College of Health Sciences, Abu Dhabi University, Abu Dhabi, United Arab Emirates; 3Institute of Urban Agriculture, Chinese Academy of Agricultural Sciences, Chengdu National Agricultural Science and Technology Center, Chengdu, People’s Republic of China; 4College of Plant Science & Technology, Huazhong Agricultural University, Wuhan, People’s Republic of ChinaCorrespondence: Abdul Jaleel, Department of Integrative Agriculture, College of Agriculture and Veterinary Medicine, United Arab Emirates University, Al Ain, United Arab Emirates, Tel +9713-7134558, Email abdul.jaleel@uaeu.ac.aeAbstract: Cancer has emerged as a formidable global health challenge, with treatment methods like chemotherapy and radiation often exacerbating the situation due to their associated side effects. Opting for natural sources like plants as a safer and environmentally friendly alternative seems promising. Historically, plants have served as valuable sources for treating diverse health conditions, attributable to their rich composition of therapeutic phytochemicals. Within this array of phytochemicals, alkaloids, especially those found in the Solanaceae plant family, are notably prominent. Alkaloids from Solanaceae plant family called Solanum alkaloids demonstrate noteworthy anti-tumour characteristics and exert a potent inhibitory influence on cancer cell proliferation. They trigger programmed cell death in cancerous cells through various molecular pathways, whether administered alone or combined with other medications. Solanum alkaloids act upon cancer cells via multiple mechanisms, including apoptosis induction, suppression of cell growth and migration, as well as inhibition of angiogenesis. This review provides insights into the anti-cancer attributes of Solanum alkaloids found in various Solanum plant species, along with a brief overview of their other medicinal properties.Keywords: Solanum alkaloids, anticancer, apoptosis, molecular mechanism, structure function relationship, therapeutic values

Blockchain networks continue to gain attraction in cutting‐edge applications and mining within these networks has become increasingly popular. To get rewards, miners solve cryptographic puzzles and add new blocks to blockchain networks using the proof‐of‐work (PoW) consensus mechanism. Numerous miners opt to participate in mining pools due to the challenges of solo mining. However, selecting reputed miners for pool mining poses a significant challenge, given the decentralized nature of the blockchain system. This paper addresses this challenge by introducing a new ranking model that evaluates miners' performance and reputation through trust scores. It provides a method for optimizing pool mining performance by identifying highly reputed miners within mining pools, enhancing overall pool profitability. This endeavor necessitates the development of ranking algorithms tailored to the unique dynamics of mining pools. The research offers a meticulously designed ranking model that identifies reputed miners. We extensively evaluate the proposed model using the hyperledger blockchain framework, guaranteeing strong performance across vital metrics like block authorization time, Processing time, block creation time, validation time, and confirmation time. [ABSTRACT FROM AUTHOR]

Aim of the Study: To describe methods and outcomes of using the forehead flap for reconstruction in patients with diverse facial defects. Patients and Methods: A retrospective analysis was conducted on patients who underwent forehead flap surgery for facial defect reconstruction at our centre between January 2022 and December 2023. This comprised of 7 individuals with various aetiologies. Patient demographics, preoperative assessments, surgical details, postoperative complications, and long-term outcomes were studied. Results: Of the 7 patients included in the study, 4 had post traumatic defects, 3 had defects following surgical resection. Forehead flap had been used for reconstruction of scalp, eyelids, nose, palate, lips and floor of mouth. Surgical outcomes were mostly successful with good patient satisfaction, although some patients had peri-operative complications due to co-existing morbidities. Conclusion: Forehead flaps are versatile, effective, reliable with tolerable morbidity; and can hence be used for addressing a variety of craniofacial defects [ABSTRACT FROM AUTHOR]

This article, published in the Journal of Cardiovascular Disease Research, discusses a study on faciomaxillary injuries in females. The study aims to evaluate the incidence, etiology, fracture patterns, and management of these injuries. The results show that the most common cause of these injuries is road traffic accidents, followed by assault. Mandibular fractures were found to be the most common, and most fractures were managed operatively. The study highlights the importance of understanding the risk factors and implementing safety measures to prevent these injuries. [Extracted from the article]

In this study, the vibration analysis of fully and partially treated laminated composite Magnetorheological (MR) fluid sandwich plates has been investigated experimentally. The natural frequencies of fully and partially treated laminated composite MR fluid sandwich plates have been measured at various magnetic field intensities under two different boundary conditions. The variations of natural frequencies with applied magnetic field, boundary conditions and location of MR fluid pocket have been explored. Further, a comparison of natural frequencies of fully and partially treated MR fluid sandwich structure has been made at various magnetic field intensities.

Blockchain technology is a revolution started as a new economy with an alternative currency namely Bitcoin. Besides the economical aspect, the technological capabilities of Blockchain such as distributed computing, record keeping, irrecoverability of transactions, reliability and etc., are harnessed by variety of real-world applications. Blockchain is a rising pool of records known as blocks linked using security procedure. It is typically managed by a group of nodes in a distributed network technology which integrates technologies such as distributed ledger, security and consensus algorithm to ensure reliability and immutability. In Blockchain, the access privileges are determined by a set of nodes called miners, which run the consensus algorithm to access and submit transactions in to the block after authentication. However, in the existing Blockchain, there is no mechanism to ensure the trust and robustness of the miners and eliminate the malicious miners which runs the consensus algorithm. Therefore, this paper proposes a trust model with an objective of eliminating untrusted nodes from the mining process to enhance the reliability and security of the Blockchain. Further, the proposed trust model is suitably analysed for transaction rate, efficiency and scalability with Hyper Ledger framework to ensure the robustness. [ABSTRACT FROM AUTHOR]

In this paper we discuss signed product cordial labeling in the context of arbitrary supersubdivision of some special graphs. We prove that the graph obtained by arbitrary supersubdivision of ([P.sub.n] x [P.sub.m]) [??] [P.sub.s] is signed product cordial. We also prove that the tadpole [T.sub.n,l] is signed product cordial except [m.sub.i] (1 [less than or equal to] i ≤ n) are odd, [m.sub.i] (n + 1 [less than or equal to] i ≤ n + l) are even and n is odd and [C.sub.n] [??] [P.sub.m] is signed product cordial except [m.sub.i] (1 [less than or equal to] i ≤ n) are odd, [m.sub.i] (n + 1 ≤ i ≤ nm) are even and n is odd. Keywords Signed product cordial labeling, signed product cordial graph, tadpole, arbitrary supersubdivision., §1. Introduction and preliminaries We begin with simple, finite, connected and undirected graph G = (V(G),E(G)) with p vertices and q edges. For all other terminology and notations we follow [...]

Problem statement: In order to bring speech into the mainstream of business process an efficient digital signal processor is necessary. The Fast Fourier Transform (FFT) and the butter fly structure symmetry will enable the harwaring easier. With the DSP and software proposed, togetherly established by means of a system, named here as 'Speech Abiding System (SAS)', a software agent, which involves the digital representation of speech signals and the use of digital processors to analyze, synthesize, or modify such signals. The proposed SAS addresses the issues in two parts. Part I: Capturing the Speaker and the Language independent error free Speech Content for speech applications processing and Part II: To accomplish the speech content as an input to the Speech User Applications/Interface (SUI). Approach: Discrete Fourier Transform (DFT) of the speech signal is the essential ingredient to evolve this SAS and Discrete-Time Fourier Transform (DTFT) links the discrete-time domain to the continuous-frequency domain. The direct computation of DFT is prohibitively expensive in terms of the required computer operations. Fortunately, a number of 'fast' transforms have been developed that are mathematically equivalent to the DFT, but which require significantly a fewer computer operations for their implementation. Results: From Part-I, the SAS able to capture an error free Speech content to facilitate the speech as a good input in the main stream of business processing. Part-II provides an environment to implement the speech user applications at a primitive level. Conclusion/Recommendations: The SAS agent along with the required hardware architecture, a Finite State Automata (FSA) machine can be created to develop global oriented domain specific speech user applications easily. It will have a major impact on interoperability and disintermediation in the Information Technology Cycle (ITC) for computer program generating. Key words: Speech abiding systems, speech science, speech technology, speech user interface, speech user applications, MS speech server, SALT, companding, INTRODUCTION Speech and natural language understanding are the key technologies that will have the most impact in the next 15 years. Enabling users to speak and listen to a computer [...]