174 results on '"Manser, Edward"'
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2. Insights into the evolution of regulated actin dynamics via characterization of primitive gelsolin/cofilin proteins from Asgard archaea
3. Proximity proteomics identifies PAK4 as a component of Afadin–Nectin junctions
4. Data from PRL-3 Down-regulates PTEN Expression and Signals through PI3K to Promote Epithelial-Mesenchymal Transition
5. Supplementary Figure 1 from PRL-3 Down-regulates PTEN Expression and Signals through PI3K to Promote Epithelial-Mesenchymal Transition
6. Faculty Opinions recommendation of MICAL1 activation by PAK1 mediates actin filament disassembly.
7. Faculty Opinions recommendation of Engineered kinases as a tool for phosphorylation of selected targets in vivo.
8. Tensin3 interaction with talin drives the formation of fibronectin-associated fibrillar adhesions
9. Roles of PAK Family Kinases
10. Regulation of phosphorylation pathways by p21 GTPases : The p21 Ras-related Rho subfamily and its role in phosphorylation signalling pathways
11. Structural and biochemical evidence for the emergence of a calcium-regulated actin cytoskeleton prior to eukaryogenesis
12. The Drosophila homologue of Arf-GAP GIT1, dGIT, is required for proper muscle morphogenesis and guidance during embryogenesis
13. Bcl-xL and UVRAG Cause a Monomer-Dimer Switch in Beclin1
14. PAK Is Regulated by PI3K, PIX, CDC42, and PP2Cα and Mediates Focal Adhesion Turnover in the Hyperosmotic Stress-induced p38 Pathway
15. Tensin3 interaction with talin drives formation of fibronectin-associated fibrillar adhesions
16. Protein kinases required for segregation of vimentin filaments in mitotic process
17. A PAK1–PIX–PKL complex is activated by the T‐cell receptor independent of Nck, Slp‐76 and LAT
18. The structure of the actin filament uncapping complex mediated by twinfilin
19. Structure of the small G protein Cdc42 bound to the GTPase-binding domain of ACK
20. PAK promotes morphological changes by acting upstream of Rac
21. PDZK1: I. A major scaffolder in brush borders of proximal tubular cells
22. A brain serine/threonine protein kinase activated by Cdc42 and Rac1
23. Phosphorylation and reorganization of vimentin by p21-activated kinase (PAK)
24. A non-receptor tyrosine kinase that inhibits the GTPase activity of p21 (supercdc42)
25. Regulation of phosphorylation pathways by p21 GTPases
26. [24] Purification and assay of kinases that interact with Rac/Cdc42
27. [16] Identification of GTPase-activating proteins by nitrocellulose overlay assay
28. Complex eukaryotic-like actin regulation systems from Asgard archaea
29. Cdc42 antagonizes inductive action of cAMP on cell shape, via effects of the myotonic dystrophy kinase-related Cdc42-binding kinase (MRCK) on myosin light chain phosphorylation
30. Blot Overlays with 32P-Labeled Fusion Proteins
31. The Tyrosine Kinase ACK1 Associates with Clathrin-coated Vesicles through a Binding Motif Shared by Arrestin and Other Adaptors
32. The Mechanism of PAK Activation: AUTOPHOSPHORYLATION EVENTS IN BOTH REGULATORY AND KINASE DOMAINS CONTROL ACTIVITY
33. p21-Activated Kinase PAK Phosphorylates Desmin at Sites Different from Those for Rho-Associated Kinase
34. Group-I PAKs-mediated phosphorylation of HACE1 at serine 385 regulates its oligomerization state and Rac1 ubiquitination
35. The GTPase Cycle: How Dominant Inhibitory Mutants Block the Biological Functions of Small GTPases
36. Identification and Characterization of Small GTPase-Associated Kinases
37. Rho GTPases and Regulation of Cell Migration and Polarization in Human Corneal Epithelial Cells
38. PTB Domain-Directed Substrate Targeting in a Tyrosine Kinase from the Unicellular Choanoflagellate Monosiga brevicollis
39. The leading edge during dorsal closure as a model for epithelial plasticity: Pak is required for recruitment of the Scribble complex and septate junction formation
40. Faculty Opinions recommendation of Endogenous RhoG is dispensable for integrin-mediated cell spreading but contributes to Rac-independent migration.
41. Functional interactions between phosphatase POPX2 and mDia modulate RhoA pathways
42. Autophosphorylation-dependent degradation of Pak1, triggered by the Rho-family GTPase, Chp
43. PRL-3 Down-regulates PTEN Expression and Signals through PI3K to Promote Epithelial-Mesenchymal Transition
44. Chapter 37 - Blot Overlays with 32P-Labeled GST-Ras Fusion Proteins: Application to Mapping Protein-Protein Interaction Sites
45. The p21-Activated Kinase PAK Is Negatively Regulated by POPX1 and POPX2, a Pair of Serine/Threonine Phosphatases of the PP2C Family
46. The GTPase Cycle How Dominant Inhibitory Mutants Block the Biological Functions of Small GTPases.
47. Coupling of PAK-Interacting Exchange Factor PIX to GIT1 Promotes Focal Complex Disassembly
48. Interaction between PAK and Nck: a Template for Nck Targets and Role of PAK Autophosphorylation
49. cAMP-induced Morphological Changes Are Counteracted by the Activated RhoA Small GTPase and the Rho Kinase ROKα
50. A Conserved Negative Regulatory Region in αPAK: Inhibition of PAK Kinases Reveals Their Morphological Roles Downstream of Cdc42 and Rac1
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