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Your search keyword '"Marchì, Salvatore"' showing total 9 results
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9 results on '"Marchì, Salvatore"'

4. Cardiac Toxicity of 5-Fluorouracil Report of a Case of Spontaneous Angina

Author

Mancuso, Luigi, Bondì, Francesco, Marchì, Salvatore, Iacona, Maria Aurora, and Di Gregorio, Luigi

Abstract

We report a case of a patient with colon carcinoma and liver metastasis who presented chest pain after 5-fluorouracil (5-FU) administration. Clinical electrocardiographic evolution was similar to that observed in Prinzmetal's angina, and chest pain promptly resolved with nifedipine. These data suggest that coronary spasm may be the cause of cardiotoxicity due to 5-FU, and that calcium antagonists may probably be used in the prevention or treatment of 5-FU cardiotoxicity.

Published
1986
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9. [A strange case of acute respiratory failure: the platypnea-orthodeoxia syndrome].

Author

Pieri P, Vitale G, Pieri M, La Fata B, Buffa L, Pieri E, Marchì S, Pitrolo F, and Geraci G

Subjects
Acute Disease, Aged, Female, Foramen Ovale, Patent surgery, Humans, Patient Positioning, Respiratory Insufficiency surgery, Syndrome, Dyspnea etiology, Foramen Ovale, Patent complications, Hypoxia etiology, Respiratory Insufficiency etiology
Abstract

Platypnea-orthodeoxia syndrome is a rare disorder characterized by dyspnea and oxygen desaturation in upright position, with improvement of symptoms and blood oxygenation in supine position. Basically a right-to-left shunt (intracardiac or pulmonary) or a ventilation/perfusion mismatch are necessary to develop platypnea-orthodeoxia syndrome. Atrial septal defects, including patent foramen ovale (PFO), are known to be a frequent cause of platypnea-orthodeoxia syndrome. We describe herein the case of a 79-year-old woman with platypnea-orthodeoxia syndrome and PFO who developed a refractory worsening respiratory failure. Only the "rescue" emergency closure of PFO allowed the patient a clinical turning point with immediate and sustained respiratory improvement.

Published
2020
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