44 results on '"Marcin, Lawrence"'
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2. Triazolopyridine ethers as potent, orally active mGlu2 positive allosteric modulators for treating schizophrenia
3. Chapter 3 Secretase Inhibitors and Modulators for the Treatment of Alzheimer's Disease
4. Asymmetric construction of a quaternary carbon center by tandem (4 + 2)/(3 + 2) cycloaddition of a nitroalkene. The total synthesis of (-)-mesembrine
5. Application of (R)-(-)-2,2-diphenylcyclopentanol as the chiral auxiliary
6. Asymmetric nitroalkene [4+2] cycloadditions: enantioselective synthesis of 3-substituted and 3,4-disubstituted pyrrolidines
7. Nitroalkene (4 + 2) cycloaddition as a general and stereoselective route to the synthesis of 3,3- and 3,4-disubstituted pyrrolidines
8. A general method for the preparation of 2,2-disubstituted 1-nitroalkenes
9. Identification and Preclinical Evaluation of the Bicyclic Pyrimidine γ-Secretase Modulator BMS-932481
10. BMS-986163, a Negative Allosteric Modulator of GluN2B with Potential Utility in Major Depressive Disorder
11. Preclinical Characterization of (R)-3-((3S,4S)-3-fluoro-4-(4-hydroxyphenyl)piperidin-1-yl)-1-(4-methylbenzyl)pyrrolidin-2-one (BMS-986169), a Novel, Intravenous, Glutamate N-Methyl-d-Aspartate 2B Receptor Negative Allosteric Modulator with Potential in Major Depressive Disorder
12. Discovery of S3-Truncated, C-6 Heteroaryl Substituted Aminothiazine β-Site APP Cleaving Enzyme-1 (BACE1) Inhibitors
13. Synthesis of β-disubstituted β-amino isoxazolyl ketones by addition of ketimines with isoxazolyl methyl ketone enolates
14. Synthesis and SAR of indole-and 7-azaindole-1,3-dicarboxamide hydroxyethylamine inhibitors of BACE-1
15. Discovery of S3-Truncated, C-6 Heteroaryl Substituted Aminothiazine β-Site APP Cleaving Enzyme-1 (BACE1) Inhibitors.
16. Synthesis and hSERT activity of homotryptamine analogs. Part 6: [3+2] dipolar cycloaddition of 3-vinylindoles
17. ChemInform Abstract: Synthesis of β-Disubstituted β-Amino Isoxazolyl Ketones by Addition of Ketimines with Isoxazolyl Methyl Ketone Enolates.
18. Identification and Preclinical Pharmacology of theγ-Secretase Modulator BMS-869780
19. Total synthesis of (-)(+)-batrachotoxinin A
20. ChemInform Abstract: Synthesis and hSERT Activity of Homotryptamine Analogues. Part 6. [3 + 2] Dipolar Cycloaddition of 3‐Vinylindoles.
21. ChemInform Abstract: A Useful Modification of the Garst-Spencer Furan Annulation: An Improved Synthesis of 3,4-Substituted Furans.
22. Discovery and Evaluation of BMS-708163, a Potent, Selective and Orally Bioavailable γ-Secretase Inhibitor
23. Conformationally restricted homotryptamines. Part 4: Heterocyclic and naphthyl analogs of a potent selective serotonin reuptake inhibitor
24. P-Glycoprotein Efflux and Other Factors Limit Brain Amyloid β Reduction by β-Site Amyloid Precursor Protein-Cleaving Enzyme 1 Inhibitors in Mice
25. trans-2,5-Dimethylpyrrolidine
26. Catalytic Asymmetric Diazoacetate Cyclopropanation of 1-Tosyl-3-vinylindoles. A Route to Conformationally Restricted Homotryptamines.
27. Conformationally Restricted Homotryptamines. 2. Indole Cyclopropylmethylamines as Selective Serotonin Reuptake Inhibitors
28. Microwave‐assisted synthesis and chiral HPLC separation of 18F‐labeled MaxiPost™. An agent for post‐stroke neuroprotection
29. (R)-(−)-2,2-Diphenylcyclopentanol
30. trans-2,5-Dimethylpyrrolidine
31. A useful modification of the Garst-Spencer furan annulation: An improved synthesis of 3,4-substituted furans
32. Total Synthesis of (±)-Batrachotoxinin A
33. Asymmetric Construction of a Quaternary Carbon Center by Tandem [4 + 2]/[3 + 2] Cycloaddition of a Nitroalkene. The Total Synthesis of (−)-Mesembrine
34. Nitroalkene Inter [4 + 2]/Intra [3 + 2] Tandem Cycloadditions. 7. Application of (R)-(-)-2,2-Diphenylcyclopentanol as the Chiral Auxiliary
35. Asymmetric Nitroalkene [4 + 2] Cycloadditions: Enantioselective Synthesis of 3-Substituted and 3,4-Disubstituted Pyrrolidines
36. Nitroalkene [4+2] cycloaddition as a general and stereoselective route to the synthesis of 3,3- and 3,4-disubstituted pyrrolidines
37. P-glycoprotein efflux and other factors limit brain amyloid beta reduction by beta-site amyloid precursor protein-cleaving enzyme 1 inhibitors in mice.
38. Microwave-assisted synthesis and chiral HPLC separation of <SUP>18</SUP>F-labeled MaxiPost<SC></SC>. An agent for post-stroke neuroprotection
39. Compounds For The Treatment Of Premature Ejaculation
40. ChemInform Abstract: A Useful Modification of the Garst-Spencer Furan Annulation: An Improved Synthesis of 3,4-Substituted Furans.
41. Mitsunobu reactions of n-alkyl and n-acyl sulfonamides-an efficient route to protected amines
42. Preclinical Characterization of ( R )-3-((3 S ,4 S )-3-fluoro-4-(4-hydroxyphenyl)piperidin-1-yl)-1-(4-methylbenzyl)pyrrolidin-2-one (BMS-986169), a Novel, Intravenous, Glutamate N -Methyl-d-Aspartate 2B Receptor Negative Allosteric Modulator with Potential in Major Depressive Disorder.
43. Identification and Preclinical Pharmacology of the γ-Secretase Modulator BMS-869780.
44. Catalytic asymmetric diazoacetate cyclopropanation of 1-tosyl-3-vinylindoles. A route to conformationally restricted homotryptamines.
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