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2 results on '"Marco Pontes"'

1. Longer-term safety and efficacy of baricitinib for atopic dermatitis in pediatric patients 2 to

Author

Andreas Wollenberg, Masanori Ikeda, Chia-Yu Chu, Lawrence F. Eichenfield, Marieke M. B. Seyger, Apurva Prakash, Robinette Angle, Danting Zhu, Marco Pontes, and Amy S. Paller

Subjects
Atopic dermatitis, pediatric, baricitinib, Dermatology, RL1-803
Abstract

Background Baricitinib, an oral selective Janus kinase inhibitor, improved clinical signs and symptoms of moderate-to-severe atopic dermatitis (AD) at week 16 in the phase 3 pediatric study BREEZE-AD-PEDS.Objective To assess longer-term efficacy and safety of baricitinib in pediatric patients aged 2 to

Published
2024
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2. PHOTODYNAMIC THERAPY FOR BISPHOSPHONATE-RELATED OSTEONECROSIS IN PALATINE TORUS: A CASE REPORT

Author

Rosemiro De Menezes Maciel, Mônica Simões Israel, Marco Pontes, Giulianna Lima Pinheiro, Wagner Pinto Das Chagas, Nathália De Almeida Freire, and Maria Eliza Barbosa Ramos

Subjects
medicine.medical_specialty, medicine.diagnostic_test, business.industry, medicine.medical_treatment, Osteoporosis, Photodynamic therapy, Physical examination, Bisphosphonate, medicine.disease, Pathology and Forensic Medicine, Surgery, Metastasis, Lesion, medicine.anatomical_structure, medicine, Radiology, Nuclear Medicine and imaging, Dentistry (miscellaneous), Hard palate, Oral Surgery, medicine.symptom, Osteonecrosis of the jaw, business
Abstract

Bisphosphonates (BPs) are widely used as first-line therapy for osteoporosis or metastasis of malignant neoplasms to bone. However, one of the severe late complications of the long-time use of BPs is bisphosphonate-related osteonecrosis of the jaw (BRONJ). Osteonecrosis of the jaws can affect quality of life because of feeding limitations and intense pain. This case report demonstrates the use of photodynamic therapy (PDT) in a bisphosphonate-related lesion, in a 75-year-old female who used alendronate for 7 years. Clinical examination revealed a firm lesion with ulcerated center, about 3 cm, located in the hard palate. The diagnostic of BRONJ was clinically established and the decision was to initiate photodynamic therapy (PDT) mediated by methylene blue. Laser treatment was provided weekly for a total of 7 treatment sessions. Follow-up examination 3 months later showed no evidence of recurrence.

Published
2020
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