Search

Your search keyword '"Marconi, Giovanni"' showing total 443 results
Start Over Author "Marconi, Giovanni"
443 results on '"Marconi, Giovanni"'

1. Venetoclax and hypomethylating agents in octogenarians and nonagenarians with acute myeloid leukemia

Author

Madarang, Ellen, Lykon, Jillian, Zhao, Wei, Sekeres, Mikkael A., Bradley, Terrence, Chandhok, Namrata S., Taylor, Justin, Venugopal, Sangeetha, Koru-Sengul, Tulay, Iyer, Sunil Girish, Gilbert, Jason S., Miller, Ryan M., Nanni, Jacopo, Zacheo, Irene, Mattei, Agnese, Al Ali, Najla, Kishtagari, Ashwin, Marconi, Giovanni, Sallman, David A., Pollyea, Daniel A., Savona, Michael R., Papayannidis, Cristina, Komrokji, Rami, and Watts, Justin

Published
2024
Full Text
View/download PDF

5. Author Correction: Genome-wide association study identifies susceptibility loci for acute myeloid leukemia

Author

Lin, Wei-Yu, Fordham, Sarah E., Hungate, Eric, Sunter, Nicola J., Elstob, Claire, Xu, Yaobo, Park, Catherine, Quante, Anne, Strauch, Konstantin, Gieger, Christian, Skol, Andrew, Rahman, Thahira, Sucheston-Campbell, Lara, Wang, Junke, Hahn, Theresa, Clay-Gilmour, Alyssa I., Jones, Gail L., Marr, Helen J., Jackson, Graham H., Menne, Tobias, Collin, Mathew, Ivey, Adam, Hills, Robert K., Burnett, Alan K., Russell, Nigel H., Fitzgibbon, Jude, Larson, Richard A., Le Beau, Michelle M., Stock, Wendy, Heidenreich, Olaf, Alharbi, Abrar, Allsup, David J., Houlston, Richard S., Norden, Jean, Dickinson, Anne M., Douglas, Elisabeth, Lendrem, Clare, Daly, Ann K., Palm, Louise, Piechocki, Kim, Jeffries, Sally, Bornhäuser, Martin, Röllig, Christoph, Altmann, Heidi, Ruhnke, Leo, Kunadt, Desiree, Wagenführ, Lisa, Cordell, Heather J., Darlay, Rebecca, Andersen, Mette K., Fontana, Maria C., Martinelli, Giovanni, Marconi, Giovanni, Sanz, Miguel A., Cervera, José, Gómez-Seguí, Inés, Cluzeau, Thomas, Moreilhon, Chimène, Raynaud, Sophie, Sill, Heinz, Voso, Maria Teresa, Lo-Coco, Francesco, Dombret, Hervé, Cheok, Meyling, Preudhomme, Claude, Gale, Rosemary E., Linch, David, Gaal-Wesinger, Julia, Masszi, Andras, Nowak, Daniel, Hofmann, Wolf-Karsten, Gilkes, Amanda, Porkka, Kimmo, Milosevic Feenstra, Jelena D., Kralovics, Robert, Grimwade, David, Meggendorfer, Manja, Haferlach, Torsten, Krizsán, Szilvia, Bödör, Csaba, Stölzel, Friedrich, Onel, Kenan, and Allan, James M.

Published
2022
Full Text
View/download PDF

6. INCB84344-201: Ponatinib and steroids in frontline therapy for unfit patients with Ph+ acute lymphoblastic leukemia

Author

Martinelli, Giovanni, Papayannidis, Cristina, Piciocchi, Alfonso, Robustelli, Valentina, Soverini, Simona, Terragna, Carolina, Marconi, Giovanni, Lemoli, Roberto M., Guolo, Fabio, Fornaro, Antonella, Lunghi, Monia, de Fabritiis, Paolo, Candoni, Anna, Selleri, Carmine, Simonetti, Federico, Bocchia, Monica, Vitale, Antonella, Frison, Luca, Tedeschi, Alessandra, Cuneo, Antonio, Bonifacio, Massimiliano, Martelli, Maria Paola, D'Ardia, Stefano, Trappolini, Silvia, Tosi, Patrizia, Galieni, Piero, Fabbiano, Francesco, Abbenante, Maria Chiara, Granier, Muriel, Zhu, Zhaoyin, Wang, Mingyue, Sartor, Chiara, Paolini, Stefania, Cavo, Michele, Foà, Robin, Fazi, Paola, Vignetti, Marco, and Baccarani, Michele

Published
2022
Full Text
View/download PDF

8. Novel insights and therapeutic approaches in secondary AML.

Author

Marconi, Giovanni, Rondoni, Michela, Zannetti, Beatrice Anna, Zacheo, Irene, Nappi, Davide, Mattei, Agnese, Rocchi, Serena, and Lanza, Francesco

Subjects
ACUTE myeloid leukemia, STEM cell transplantation, HEMATOLOGICAL oncology, THERAPEUTICS, VENETOCLAX
Abstract

Secondary acute myeloid leukemia (sAML) presents as a complex and multifaceted ensemble of disorders, positioning itself as both a challenge and an intriguing frontier within hematologic oncology. Its origins are diverse, stemming from antecedent hematologic conditions, germline predisposing mutations, or the sequelae of cytotoxic therapies, and its development is driven by intricate genetic and epigenetic modifications. This complexity necessitates a diverse array of therapeutic strategies, each meticulously tailored to address the distinctive challenges sAML introduces. Such strategies require a personalized approach, considering the variegated clinical backgrounds of patients and the inherent intricacies of the disease. Allogeneic stem cell transplantation stands as a cornerstone, offering the potential for curative outcomes. This is complemented by the emergence of innovative treatments such as CPX-351, venetoclax, and glasdegib, which have demonstrated promising results in enhancing prognosis. The evolving landscape of sAML treatment underscores the importance of continued research and innovation in the field, aiming not only to improve patient outcomes but also to deepen our understanding of the disease's biological underpinnings, thereby illuminating pathways toward more effective and individualized therapies. [ABSTRACT FROM AUTHOR]

Published
2024
Full Text
View/download PDF

9. Casa

Author

Ranuccio Bianchi Bandinelli, Giulio Farina, Plinio Marconi, Giovanni Patroni, Romeo Vuoli, Paola Zancani Montuoro and Ranuccio Bianchi Bandinelli, Giulio Farina, Plinio Marconi, Giovanni Patroni, Romeo Vuoli, Paola Zancani Montuoro

Published
2022

10. Integrated genomic-metabolic classification of acute myeloid leukemia defines a subgroup with NPM1 and cohesin/DNA damage mutations

Author

Simonetti, Giorgia, Mengucci, Carlo, Padella, Antonella, Fonzi, Eugenio, Picone, Gianfranco, Delpino, Claudio, Nanni, Jacopo, De Tommaso, Rossella, Franchini, Eugenia, Papayannidis, Cristina, Marconi, Giovanni, Pazzaglia, Martina, Perricone, Margherita, Scarpi, Emanuela, Fontana, Maria Chiara, Bruno, Samantha, Tebaldi, Michela, Ferrari, Anna, Bochicchio, Maria Teresa, Ghelli Luserna Di Rorà, Andrea, Ghetti, Martina, Napolitano, Roberta, Astolfi, Annalisa, Baldazzi, Carmen, Guadagnuolo, Viviana, Ottaviani, Emanuela, Iacobucci, Ilaria, Cavo, Michele, Castellani, Gastone, Haferlach, Torsten, Remondini, Daniel, Capozzi, Francesco, and Martinelli, Giovanni

Published
2021
Full Text
View/download PDF

11. Unlocking the potential of synthetic patients for accelerating clinical trials: Results of the first GIMEMA experience on acute myeloid leukemia patients

Author

Piciocchi, Alfonso, primary, Cipriani, Marta, additional, Messina, Monica, additional, Marconi, Giovanni, additional, Arena, Valentina, additional, Soddu, Stefano, additional, Crea, Enrico, additional, Feraco, Maria Valeria, additional, Ferrante, Marco, additional, La Sala, Edoardo, additional, Fazi, Paola, additional, Buccisano, Francesco, additional, Voso, Maria Teresa, additional, Martinelli, Giovanni, additional, Venditti, Adriano, additional, and Vignetti, Marco, additional

Published
2024
Full Text
View/download PDF

12. Safety profile and impact on survival of tyrosine kinase inhibitors versus conventional therapy in relapse or refractory FLT3 positive acute myeloid leukemia patients

Author

Marconi, Giovanni, De Polo, Stefano, Martinelli, Giovanni, Nanni, Jacopo, Bertamini, Luca, Talami, Annalisa, Olivi, Matteo, Ragaini, Simone, Abbenante, Maria Chiara, Sartor, Chiara, Ottaviani, Emanuela, Bochicchio, Maria Teresa, Parisi, Sarah, Fontana, Maria Chiara, Cristiano, Gianluca, Raffini, Maddalena, Baldazzi, Carmen, Testoni, Nicoletta, Bonifazi, Francesca, Paolini, Stefania, Curti, Antonio, Cavo, Michele, and Papayannidis, Cristina

Published
2021
Full Text
View/download PDF

13. Multiple Myeloma: The Role of Autologous Stem Cell Transplantation in the Era of Immunotherapy.

Author

Rocchi, Serena, Zannetti, Beatrice Anna, Marconi, Giovanni, and Lanza, Francesco

Subjects
STEM cell transplantation, MULTIPLE myeloma, BISPECIFIC antibodies, IMMUNOTHERAPY, CHIMERIC antigen receptors, MONOCLONAL antibodies, BRAIN death, T cells
Abstract

Upfront high-dose therapy with melphalan (HDM) followed by autologous stem cell transplantation (ASCT) has established itself as a core treatment for newly diagnosed multiple myeloma (NDMM) patients in the past 30 years. Induction therapy, HDM-ASCT, and subsequent consolidation and maintenance therapy comprise the current fundamental framework for MM treatment. The introduction of anti-CD38 monoclonal antibodies such as daratumumab and isatuximab has changed the treatment paradigm for transplant-eligible NDMM patients in that quadruplets have become the new standard induction therapy. The treatment landscape of MM is undergoing a transformative shift with the introduction of potent new immunotherapies, such as chimeric antigen receptor (CAR)-T cells and bispecific antibodies (BsAbs), which are currently used in the relapsed/refractory setting (RRMM) and are already being tested in the NDMM. This review will focus on the incorporation of immunotherapy in the treatment scenario of NDMM patients eligible for ASCT. [ABSTRACT FROM AUTHOR]

Published
2024
Full Text
View/download PDF

14. ETV6::ABL1-Positive Myeloid Neoplasm: A Case of a Durable Response to Imatinib Mesylate without Additional or Previous Treatment

Author

Bochicchio, Maria Teresa, primary, Marconi, Giovanni, additional, Baldazzi, Carmen, additional, Bandini, Lorenza, additional, Ruggieri, Francesca, additional, Lucchesi, Alessandro, additional, Agostinelli, Claudio, additional, Sabattini, Elena, additional, Orsatti, Agnese, additional, Ferrari, Anna, additional, Capirossi, Giorgia, additional, Servili, Chiara, additional, Ghelli Luserna di Rorà, Andrea, additional, Martinelli, Giovanni, additional, Simonetti, Giorgia, additional, and Rosti, Gianantonio, additional

Published
2023
Full Text
View/download PDF

15. Impact of inotuzumab ozogamicin on outcome in relapsed or refractory acute B-cell lymphoblastic leukemia patients prior to allogeneic hematopoietic stem cell transplantation and risk of sinusoidal obstruction syndrome/venous occlusive disease

Author

Kayser, Sabine, primary, Sartor, Chiara, additional, Giglio, Fabio, additional, Bruno, Alessandro, additional, Webster, Jonathan, additional, Chiusolo, Patrizia, additional, Saraceni, Francesco, additional, Guerzoni, Selene, additional, Pochintesta, Lara, additional, Borlenghi, Erika, additional, Marconi, Giovanni, additional, Zacheo, Irene, additional, Cerrano, Marco, additional, Salutari, Prassede, additional, Restuccia, Francesco, additional, Abbenante, Mariachiara, additional, Levis, Mark J., additional, Schlenk, Richard F., additional, and Papayannidis, Cristina, additional

Published
2023
Full Text
View/download PDF

16. Genome-wide association study identifies susceptibility loci for acute myeloid leukemia

Author

Lin, Wei-Yu, Fordham, Sarah E., Hungate, Eric, Sunter, Nicola J., Elstob, Claire, Xu, Yaobo, Park, Catherine, Quante, Anne, Strauch, Konstantin, Gieger, Christian, Skol, Andrew, Rahman, Thahira, Sucheston-Campbell, Lara, Wang, Junke, Hahn, Theresa, Clay-Gilmour, Alyssa I., Jones, Gail L., Marr, Helen J., Jackson, Graham H., Menne, Tobias, Collin, Mathew, Ivey, Adam, Hills, Robert K., Burnett, Alan K., Russell, Nigel H., Fitzgibbon, Jude, Larson, Richard A., Le Beau, Michelle M., Stock, Wendy, Heidenreich, Olaf, Alharbi, Abrar, Allsup, David J., Houlston, Richard S., Norden, Jean, Dickinson, Anne M., Douglas, Elisabeth, Lendrem, Clare, Daly, Ann K., Palm, Louise, Piechocki, Kim, Jeffries, Sally, Bornhäuser, Martin, Röllig, Christoph, Altmann, Heidi, Ruhnke, Leo, Kunadt, Desiree, Wagenführ, Lisa, Cordell, Heather J., Darlay, Rebecca, Andersen, Mette K., Fontana, Maria C., Martinelli, Giovanni, Marconi, Giovanni, Sanz, Miguel A., Cervera, José, Gómez-Seguí, Inés, Cluzeau, Thomas, Moreilhon, Chimène, Raynaud, Sophie, Sill, Heinz, Voso, Maria Teresa, Lo-Coco, Francesco, Dombret, Hervé, Cheok, Meyling, Preudhomme, Claude, Gale, Rosemary E., Linch, David, Gaal-Wesinger, Julia, Masszi, Andras, Nowak, Daniel, Hofmann, Wolf-Karsten, Gilkes, Amanda, Porkka, Kimmo, Milosevic Feenstra, Jelena D., Kralovics, Robert, Grimwade, David, Meggendorfer, Manja, Haferlach, Torsten, Krizsán, Szilvia, Bödör, Csaba, Stölzel, Friedrich, Onel, Kenan, and Allan, James M.

Published
2021
Full Text
View/download PDF

17. MDS-110 SELECT-MDS-1 Trial in Progress: A Phase 3 Randomized, Double-Blind, Placebo-Controlled Study of Tamibarotene/Azacitidine Versus Placebo/Azacitidine in Newly Diagnosed Adult Patients Selected for RARA-Positive Higher-Risk MDS

Author

DeZern, Amy, Fenaux, Pierre, Deeren, Dries, Campelo, Maria Diez, Lübbert, Michael, Krishnamurthy, Pramila, Nagy, Zsolt, Basak, Grzegorz, ová, Anna Jonáš, Geissler, Klaus, Ofran, Yishai, Volkert, Angela, Baker, Kristen, Chisholm, Jaime, Kang-Fortner, Qing, Roth, David A., Kelly, Michael, and Marconi, Giovanni

Published
2022
Full Text
View/download PDF

18. AML-389 Phase 1/2 Study of SEL24/MEN1703, a First-in-Class Dual PIM/FLT3 Kinase Inhibitor, in Patients With IDH1/2-Mutated Acute Myeloid Leukemia: The DIAMOND-01 Trial

Author

Martinelli, Giovanni, Santoro, Armando, Gambacorti-Passerini, Carlo, Polo, Susana Vives, Solomon, Scott R., Mukherjee, Sudipto, Lech-Maranda, Ewa, Levy, Moshe Yair, Wierzbowska, Agnieszka, Calbacho-Robles, María, Marconi, Giovanni, Giannini, Maria Benedetta, Cano, Isabel, Miñana, Laura Torres, Acuña-Cruz, Evelyn, Angelosanto, Noemi, Mughal, Tariq I., Galleu, Antonio, Blotta, Simona, Ravandi, Farhad, and Montesinos, Pau

Published
2022
Full Text
View/download PDF

19. AML-262 Pivekimab Sunirine (PVEK, IMGN632) Triplet With Azacitidine and Venetoclax Shows Broad Activity in Adverse Genetic Subsets of Relapsed/Refractory Acute Myeloid Leukemia and Reduced Infusion-Related Reactions

Author

Daver, Naval, Montesinos, Pau, Aribi, Ahmed, Martinelli, Giovanni, Altman, Jessica K., Wang, Eunice S., Roboz, Gail J., Burke, Patrick W., Gaidano, Gianluca, Walter, Roland B., Thomas, Xavier, Jeyakumar, Deepa, DeAngelo, Daniel J., Erba, Harry P., Todisco, Elisabetta, Begna, Kebede, Advani, Anjali, Gastaud, Lauris, de la Fuente, Adolfo, Curti, Antonio, Mendez, Lourdes M., Vyas, Paresh, Boissel, Nicolas, Vey, Norbert, Recher, Christian, Longval, Thomas, Platzbecker, Uwe, Kapp-Schwörer, Silke, Schliemann, Christoph, Konopleva, Marina, Torres, Laura, Sallman, David A., Marcucci, Guido, Marconi, Giovanni, Kantarjian, Hagop, Sloss, Callum M., Malcolm, Karen E., Zweidler-McKay, Patrick A., and Sweet, Kendra

Published
2022
Full Text
View/download PDF

20. ETV6::ABL1 -Positive Myeloid Neoplasm: A Case of a Durable Response to Imatinib Mesylate without Additional or Previous Treatment.

Author

Bochicchio, Maria Teresa, Marconi, Giovanni, Baldazzi, Carmen, Bandini, Lorenza, Ruggieri, Francesca, Lucchesi, Alessandro, Agostinelli, Claudio, Sabattini, Elena, Orsatti, Agnese, Ferrari, Anna, Capirossi, Giorgia, Servili, Chiara, Ghelli Luserna di Rorà, Andrea, Martinelli, Giovanni, Simonetti, Giorgia, and Rosti, Gianantonio

Subjects
*IMATINIB, *NUCLEOTIDE sequencing, *HYPEREOSINOPHILIC syndrome, *PROTEIN-tyrosine kinase inhibitors, *BLOOD diseases, *TUMORS
Abstract

ETV6::ABL1 rearranged neoplasms are rare hematological diseases. To date, about 80 cases have been reported, including myeloid and lymphoid leukemias. The ETV6 gene codes for an ETS family transcription factor and several fusion partners have been described. When translocated, ETV6 causes the constitutive activation of the partner genes. Here, we report the case of a 54-year-old woman with a cryptic insertion of the 3′ region of ABL1 in the ETV6 gene. The patient was first diagnosed with idiopathic hypereosinophilic syndrome, according to the clinical history, conventional cytogenetics, standard molecular analyses and pathologist description. Next generation sequencing of diagnosis samples unexpectedly detected both ETV6::ABL1 type A and B fusion transcripts, which were then confirmed by FISH. The diagnosis was Myeloid/Lymphoid neoplasm with ETV6::ABL1 fusion, and the patient received imatinib mesylate treatment. In a follow-up after more than one year, the patient still maintained the molecular and complete hematological responses. This case highlights the importance of timely and proper diagnostics and prompt tyrosine kinase inhibitor treatment. [ABSTRACT FROM AUTHOR]

Published
2024
Full Text
View/download PDF

21. P375: INOTUZUMB OZOGAMICIN PRIOR TO ALLOGENEIC HEMATOPOIETIC STEM CELL TRANSPLANTATION IN RELAPSED OR REFRACTORY ACUTE B-LYMPHOBLASTIC LEUKEMIA

Author

Kayser, Sabine, primary, Sartor, Chiara, additional, Giglio, Fabio, additional, Bruno, Alessandro, additional, Webster, Jonathan, additional, Chiusolo, Patrizia, additional, Saraceni, Francesco, additional, Guerzoni, Selene, additional, Pochintesta, Lara, additional, Borlenghi, Erika, additional, Marconi, Giovanni, additional, Zacheo, Irene, additional, Cerrano, Marco, additional, Salutari, Prassede, additional, Restuccia, Francesco, additional, Abbenante, Mariachiara, additional, J Levis, Mark, additional, Schlenk, Richard, additional, and Papayannidis, Cristina, additional

Published
2023
Full Text
View/download PDF

22. P495: UNLOCKING THE POTENTIAL OF SYNTHETIC PATIENTS FOR ACCELERATING CLINICAL TRIALS: RESULTS OF THE FIRST GIMEMA EXPERIENCE

Author

Piciocchi, Alfonso, primary, Cipriani, Marta, additional, Messina, Monica, additional, Marconi, Giovanni, additional, Arena, Valentina, additional, Soddu, Stefano, additional, Crea, Enrico, additional, Valeria Feraco, Maria, additional, Ferrante, Marco, additional, la Sala, Edoardo, additional, Fazi, Paola, additional, Buccisano, Francesco, additional, Martinelli, Giovanni, additional, Venditti, Adriano, additional, and Vignetti, Marco, additional

Published
2023
Full Text
View/download PDF

23. P523: THE COMPARISON OF VFLAI, FLAI AND 3 + 7 REGIMENS BY MULTILEVEL PROPENSITY SCORE WEIGHTING HIGHLIGHTS THE BENEFIT OF THE ADDITION OF VENETOCLAX IN NO LOW-RISK AML TREATED IN GIMEMA TRIALS AND REAL WORLD

Author

Piciocchi, Alfonso, primary, Marconi, Giovanni, additional, Cipriani, Marta, additional, Messina, Monica, additional, Guolo, Fabio, additional, Minetto, Paola, additional, Paoloni, Francesca, additional, Cotugno, Francesca, additional, DI Donato, Laura, additional, Simonetti, Giorgia, additional, Palmieri, Raffaele, additional, Buccisano, Francesco, additional, Fazi, Paola, additional, Vignetti, Marco, additional, M. Lemoni, Roberto, additional, Venditti, Adriano, additional, and Martinelli, Giovanni, additional

Published
2023
Full Text
View/download PDF

24. S139: INTERIM ANALYSIS OF A REGISTRATION ENABLING STUDY OF PIVEKIMAB SUNIRINE (PVEK, IMGN632) A CD123-TARGETING ANTIBODY-DRUG CONJUGATE, IN PATIENTS WITH BLASTIC PLASMACYTOID DENDRITIC CELL NEOPLASM (BPDCN)

Author

Pemmaraju, Naveen, primary, Martinelli, Giovanni, additional, Montesinos, Pau, additional, Mazzarella, Luca, additional, Deangelo, Daniel J., additional, Erba, Harry, additional, Sweet, Kendra, additional, Walter, Roland, additional, Deconinck, Eric, additional, Legrand, Ollivier, additional, Wang, Eunice, additional, Aribi, Ahmed, additional, Ulrickson, Matthew, additional, Marconi, Giovanni, additional, Lane, Andrew, additional, Kantarjian, Hagop, additional, Sloss, Callum, additional, Malcolm, Kara, additional, Zweidler-Mckay, Patrick, additional, and Daver, Naval, additional

Published
2023
Full Text
View/download PDF

25. P553: PRELIMINARY RESULTS OF MRD ANALYSIS OF AML1718, A PHASE 2 OPEN-LABEL STUDY OF VENETOCLAX, FLUDARABINE, IDARUBICIN AND CYTARABINE (V-FLAI) IN THE INDUCTION THERAPY OF NON LOW-RISK AML

Author

Minetto, Paola, primary, Guolo, Fabio, additional, Rosellini, Sara, additional, Piciocchi, Alfonso, additional, Marconi, Giovanni, additional, Audisio, Ernesta, additional, Priolo, Giorgio, additional, Papayannidis, Cristina, additional, Martelli, Maurizio, additional, Paoloni, Francesca, additional, Bocchia, Monica, additional, Lanza, Francesco, additional, Lico, Albana, additional, Ciceri, Fabio, additional, Giovanni Della Porta, Matteo, additional, Frigeni, Marco, additional, Giaccone, Luisa, additional, Beltrami, Germana, additional, Borlenghi, Erika, additional, Chiara DI Chio, Maria, additional, Selleri, Carmine, additional, Crea, Enrico, additional, Urbino, Irene, additional, Sartor, Chiara, additional, Minotti, Clara, additional, Arena, Valentina, additional, Nanni, Jacopo, additional, Simonetti, Giorgia, additional, Teresa Bochicchio, Maria, additional, Saglio, Giuseppe, additional, Venditti, Adrianno, additional, Vignetti, Marco, additional, Fazi, Paola, additional, Tedone, Elisabetta, additional, Martinelli, Giovanni, additional, and Massimo Lemoli, Roberto, additional

Published
2023
Full Text
View/download PDF

26. PB1792: REPURPOSING OF ANTIBIOTICS INHIBITING MITOCHONDRIAL TRANSLATION IN COMBINATION WITH VENETOCLAX IN ACUTE MYELOID LEUKEMIA: FROM PRECLINICAL MODELS TO CLINICAL PRACTICE

Author

Amato, Viviana, primary, Fusani, Stefania, additional, Papayannidis, Cristina, additional, Nanni, Jacopo, additional, Curti, Antonio, additional, Marchesi, Francesco, additional, Fanciulli, Maurizio, additional, Simonetti, Giorgia, additional, Musuraca, Gerardo, additional, Marconi, Giovanni, additional, Gottardi, Michele, additional, Sperotto, Alessandra, additional, Rossi, Alessandra, additional, Maraglino, Alessio Maria Edoardo, additional, Sammassimo, Simona, additional, Gigli, Federica, additional, Todisco, Elisabetta, additional, Tarella, Corrado, additional, Giglio, Fabio, additional, and Derenzini, Enrico, additional

Published
2023
Full Text
View/download PDF

27. PB1840: OUTCOME OF ADULT ACUTE MYELOID LEUKEMIA PATIENTS WITH EXTRAMEDULLARY DISEASE AFTER TREATMENT WITH VENETOCLAX/HYPOMETHYLATING AGENTS

Author

Kayser, Sabine, primary, Sanber, Khaled, additional, Marconi, Giovanni, additional, Mattei, Agnese, additional, Luskin, Marlise, additional, Kelkar, Amar, additional, Cerrano, Marco, additional, Sartor, Chiara, additional, Giglio, Fabio, additional, Riva, Marta, additional, Rizzo, Lorenzo, additional, Saraceni, Francesco, additional, Guerzoni, Selene, additional, Lessi, Federica, additional, Borlenghi, Erika, additional, Perl, Alexander, additional, Levis, Mark J, additional, Papayannidis, Cristina, additional, Jain, Tania, additional, and Schlenk, Richard, additional

Published
2023
Full Text
View/download PDF

28. P537: SAFETY AND TOLERABILITY OF AZD0466 AS MONOTHERAPY FOR PATIENTS WITH ADVANCED HEMATOLOGICAL MALIGNANCIES - PRELIMINARY RESULTS FROM AN ONGOING PHASE I/II TRIAL

Author

Marconi, Giovanni, primary, Arslan, Shukaib, additional, Fleming, Shaun, additional, Curti, Antonio, additional, S Blachly, James, additional, Martinelli, Giovanni, additional, Giovanni Della Porta, Matteo, additional, Bajel, Ashish, additional, Sauer, Tim, additional, Crysandt, Martina, additional, Pigneux, Arnaud, additional, Konopleva, Marina, additional, Marmor, Yotvat, additional, Sharma, Shringi, additional, Elgeioushi, Nairouz, additional, Rowe, Emily, additional, Cheung, Patricia, additional, Jahn, Ekaterina, additional, Saeh, Jamal, additional, Tibes, Raoul, additional, Zumla Cader, Fathima, additional, and Jain, Nitin, additional

Published
2023
Full Text
View/download PDF

29. P547: UPFRONT INTENSIVE TREATMENT ANALYSIS OF THE ITALIAN COHORT STUDY ON FLT3-MUTATED AML PATIENTS (FLAM): THE IMPACT OF A FLT3 INHIBITOR ADDITION TO STANDARD CHEMOTHERAPY IN THE REAL-LIFE SETTING

Author

Nanni, Jacopo, primary, Mulè, Antonino, additional, Audisio, Ernesta, additional, Paola Martelli, Maria, additional, Scappini, Barbara, additional, Petracci, Elisabetta, additional, Valli, Irene, additional, Azzali, Irene, additional, Zingaretti, Chiara, additional, Benedetta Giannini, Maria, additional, Sica, Simona, additional, Cambò, Benedetta, additional, Candoni, Anna, additional, Lunghi, Monia, additional, Albano, Francesco, additional, Olivieri, Attilio, additional, Fracchiolla, Nicola, additional, Matteo Rigolin, Gian, additional, Bernardi, Massimo, additional, Romani, Claudio, additional, Todisco, Elisabetta, additional, Gigli, Federica, additional, Bocchia, Monica, additional, Cilloni, Daniela, additional, DI Renzo, Nicola, additional, Vallisa, Daniele, additional, Maria Mianulli, Anna, additional, Cignetti, Alessandro, additional, Lanza, Francesco, additional, Robustelli, Valentina, additional, Simonetti, Giorgia, additional, Teresa Bochicchio, Maria, additional, Marconi, Giovanni, additional, Flam Collaborative Group, The, additional, Papayannidis, Cristina, additional, and Martinelli, Giovanni, additional

Published
2023
Full Text
View/download PDF

30. P451: GENE FUSIONS AND OTHER GENOMIC EVENTS UNDERLIE VENETOCLAX AND HYPOMETHYLATING AGENT RESISTANCE AND PROVIDE NEW TARGETS IN ACUTE MYELOID LEUKEMIA.

Author

Ferrari, Anna, primary, Zacheo, Irene, additional, Fonzi, Eugenio, additional, Teresa Bochicchio, Maria, additional, Capirossi, Giorgia, additional, Nanni, Jacopo, additional, Paganelli, Matteo, additional, Servilli, Chiara, additional, Ledda, Lorenzo, additional, Ghetti, Martina, additional, Jandoubi, Mouna, additional, Marchesini, Matteo, additional, Mattei, Agnese, additional, Martinelli, Giovanni, additional, Simonetti, Giorgia, additional, and Marconi, Giovanni, additional

Published
2023
Full Text
View/download PDF

32. AVALON: The Italian cohort study on real-life efficacy of hypomethylating agents plus venetoclax in newly diagnosed or relapsed/refractory patients with acute myeloid leukemia

Author

Todisco, Elisabetta, Papayannidis, Cristina, Fracchiolla, Nicola, Petracci, Elisabetta, Zingaretti, Chiara, Vetro, Calogero, Martelli, Maria Paola, Zappasodi, Patrizia, Di Renzo, Nicola, Gallo, Susanna, Audisio, Ernesta, Griguolo, Davide, Cerchione, Claudio, Selleri, Carmine, Mattei, Daniele, Bernardi, Massimo, Fumagalli, Monica, Rizzuto, Giuliana, Facchini, Luca, Basilico, Claudia Maria, Manfra, Ilenia, Borlenghi, Erika, Cairoli, Roberto, Salutari, Prassede, Gottardi, Michele, Molteni, Alfredo, Martini, Vincenza, Lunghi, Monia, Fianchi, Luana, Cilloni, Daniela, Lanza, Francesco, Abruzzese, Elisabetta, Cascavilla, Nicola, Rivellini, Flavia, Ferrara, Felicetto, Maurillo, Luca, Nanni, Jacopo, Romano, Alessandra, Cardinali, Valeria, Gigli, Federica, Roncoroni, Elisa, Federico, Vincenzo, Marconi, Giovanni, Volpi, Roberta, Sciumè, Mariarita, Tarella, Corrado, Rossi, Giuseppe, Martinelli, Giovanni, Todisco, Elisabetta, Papayannidis, Cristina, Fracchiolla, Nicola, Petracci, Elisabetta, Zingaretti, Chiara, Vetro, Calogero, Martelli, Maria Paola, Zappasodi, Patrizia, Di Renzo, Nicola, Gallo, Susanna, Audisio, Ernesta, Griguolo, Davide, Cerchione, Claudio, Selleri, Carmine, Mattei, Daniele, Bernardi, Massimo, Fumagalli, Monica, Rizzuto, Giuliana, Facchini, Luca, Basilico, Claudia Maria, Manfra, Ilenia, Borlenghi, Erika, Cairoli, Roberto, Salutari, Prassede, Gottardi, Michele, Molteni, Alfredo, Martini, Vincenza, Lunghi, Monia, Fianchi, Luana, Cilloni, Daniela, Lanza, Francesco, Abruzzese, Elisabetta, Cascavilla, Nicola, Rivellini, Flavia, Ferrara, Felicetto, Maurillo, Luca, Nanni, Jacopo, Romano, Alessandra, Cardinali, Valeria, Gigli, Federica, Roncoroni, Elisa, Federico, Vincenzo, Marconi, Giovanni, Volpi, Roberta, Sciumè, Mariarita, Tarella, Corrado, Rossi, Giuseppe, Martinelli, Giovanni, Todisco, E, Papayannidis, C, Fracchiolla, N, Petracci, E, Zingaretti, C, Vetro, C, Martelli, M, Zappasodi, P, Di Renzo, N, Gallo, S, Audisio, E, Griguolo, D, Cerchione, C, Selleri, C, Mattei, D, Bernardi, M, Fumagalli, M, Rizzuto, G, Facchini, L, Basilico, C, Manfra, I, Borlenghi, E, Cairoli, R, Salutari, P, Gottardi, M, Molteni, A, Martini, V, Lunghi, M, Fianchi, L, Cilloni, D, Lanza, F, Abruzzese, E, Cascavilla, N, Rivellini, F, Ferrara, F, Maurillo, L, Nanni, J, Romano, A, Cardinali, V, Gigli, F, Roncoroni, E, Federico, V, Marconi, G, Volpi, R, Sciumè, M, Tarella, C, Rossi, G, and Martinelli, G

Subjects
Cancer Research, hypomethylating agents, Oncology, hypomethylating agent, relapsed and refractory AML, venetoclax, real-life data, acute myeloid leukemia
Abstract

Background: Venetoclax in combination with hypomethylating agents (HMA) is revolutionizing the therapy of acute myeloid leukemia (AML). However, evidence on large sets of patients is lacking, especially in relapsed or refractory leukemia. Methods: AVALON is a multicentric cohort study that was conducted in Italy on patients with AML who received venetoclax-based therapies from 2015 to 2020. The study was approved by the ethics committee of the participating institution and was conducted in accordance with the Declaration of Helsinki. The effectiveness and toxicity of venetoclax+HMA in 190 (43 newly diagnosed, 68 refractory, and 79 relapsed) patients with AML are reported here. Results: In the newly diagnosed AML, the overall response rate and survival confirmed the brilliant results demonstrated in VIALE-A. In the relapsed or refractory AML, the combination demonstrated a surprisingly complete remission rate (44.1% in refractory and 39.7% in relapsed evaluable patients) and conferred to treated patients a good expectation of survival. Toxicities were overall manageable, and most incidents occurred in the first 60days of therapy. Infections were confirmed as the most common nonhematologic adverse event. Conclusions: Real-life data show that the combination of venetoclax and HMA offers an expectation of remission and long-term survival to elderly, newly diagnosed patients, and to relapsed or chemoresistant AML, increasing the chance of cure through a different mechanism of action. The venetoclax+HMA combination is expected to constitute the base for triplet combinations and integration of target therapies. Our data contribute to ameliorate the understanding of venetoclax+HMA effectiveness and toxicities in real life.

Published
2023

33. Abstract 6163: Fusion landscape in acute leukemias: A submerged world of not routinely characterized transcripts

Author

Ferrari, Anna, primary, Vitali, Silvia, additional, Fonzi, Eugenio, additional, Di Rora, Andrea Ghelli Luserna, additional, Domizio, Chiara, additional, Papayannidis, Cristina, additional, Bochicchio, Maria Teresa, additional, Marconi, Giovanni, additional, Dall'Olio, Daniele, additional, Tebaldi, Michela, additional, Rondoni, Michela, additional, Giannini, Barbara, additional, Giglio, Fabio, additional, Pasciolla, Crescenza, additional, Fumagalli, Monica, additional, Galimberti, Sara, additional, Castellani, Gastone, additional, Remondini, Daniel, additional, Simonetti, Giorgia, additional, and Martinelli, Giovanni, additional

Published
2023
Full Text
View/download PDF

34. Chromothripsis in acute myeloid leukemia: biological features and impact on survival

Author

Fontana, Maria Chiara, Marconi, Giovanni, Feenstra, Jelena D. Milosevic, Fonzi, Eugenio, Papayannidis, Cristina, Ghelli Luserna di Rorá, Andrea, Padella, Antonella, Solli, Vincenza, Franchini, Eugenia, Ottaviani, Emanuela, Ferrari, Anna, Baldazzi, Carmen, Testoni, Nicoletta, Iacobucci, Ilaria, Soverini, Simona, Haferlach, Torsten, Guadagnuolo, Viviana, Semerad, Lukas, Doubek, Michael, Steurer, Michael, Racil, Zdenek, Paolini, Stefania, Manfrini, Marco, Cavo, Michele, Simonetti, Giorgia, Kralovics, Robert, and Martinelli, Giovanni

Published
2018
Full Text
View/download PDF

35. The baseline comorbidity burden affects survival in elderly patients with acute myeloid leukemia receiving hypomethylating agents: Results from a multicentric clinical study

Author

Marconi, Giovanni, primary, Candoni, Anna, additional, Di Nicola, Roberta, additional, Sartor, Chiara, additional, Parisi, Sarah, additional, Abbenante, Mariachiara, additional, Nanni, Jacopo, additional, Cristiano, Gianluca, additional, Zannoni, Letizia, additional, Lazzarotto, Davide, additional, Giannini, Benedetta, additional, Baldazzi, Carmen, additional, Bandini, Lorenza, additional, Ottaviani, Emanuela, additional, Testoni, Nicoletta, additional, Bezzi, Chiara Di Giovanni, additional, Abd‐alatif, Rania, additional, Ciotti, Giulia, additional, Fanin, Renato, additional, Martinelli, Giovanni, additional, Paolini, Stefania, additional, Ricci, Paolo, additional, Cavo, Michele, additional, Papayannidis, Cristina, additional, and Curti, Antonio, additional

Published
2023
Full Text
View/download PDF

37. Regions of homozygosity confer a worse prognostic impact in myelodysplastic syndrome with normal karyotype

Author

Mallo, Mar, primary, Tuechler, Heinz, additional, Arenillas, Leonor, additional, Raynaud, Sophie, additional, Cluzeau, Thomas, additional, Shih, Lee‐Yung, additional, Tung‐Liang, Chiang, additional, Ganster, Christina, additional, Shirneshan, Katayoon, additional, Haase, Detlef, additional, Mascaró, Martí, additional, Palomo, Laura, additional, Cervera, José, additional, Such, Esperanza, additional, Trim, Nicola, additional, Jeffries, Sally, additional, Ridgway, Emma, additional, Marconi, Giovanni, additional, Martinelli, Giovanni, additional, and Solé, Francesc, additional

Published
2023
Full Text
View/download PDF

41. Broad Activity for the Pivekimab Sunirine (PVEK, IMGN632), Azacitidine, and Venetoclax Triplet in High-Risk Patients with Relapsed/Refractory Acute Myeloid Leukemia (AML)

Author

Daver, Naval, primary, Montesinos, Pau, additional, Aribi, Ahmed, additional, Marconi, Giovanni, additional, Altman, Jessica K., additional, Wang, Eunice S., additional, Roboz, Gail J., additional, Burke, Patrick W., additional, Gaidano, Gianluca, additional, Walter, Roland B., additional, Thomas, Xavier, additional, Jeyakumar, Deepa, additional, DeAngelo, Daniel J., additional, Erba, Harry P., additional, Todisco, Elisabetta, additional, Begna, Kebede H., additional, Advani, Anjali, additional, Gastaud, Lauris, additional, De La Fuente, Adolfo, additional, Curti, Antonio, additional, Mendez, Lourdes M., additional, Vyas, Paresh, additional, Boissel, Nicolas, additional, Vey, Norbert, additional, Recher, Christian, additional, Longval, Thomas, additional, Platzbecker, Uwe, additional, Kapp-Schwoerer, Silke, additional, Schliemann, Christoph, additional, Konopleva, Marina, additional, Torres, Laura, additional, Sallman, David A., additional, Marcucci, Guido, additional, Pemmaraju, Naveen, additional, Martinelli, Giovanni, additional, Kantarjian, Hagop, additional, Sloss, Callum M, additional, Malcolm, Kara E, additional, Zweidler-McKay, Patrick A, additional, and Sweet, Kendra, additional

Published
2022
Full Text
View/download PDF

42. The Addition of Venetoclax to Induction Chemotherapy in No Low-Risk AML Patients: A Propensity Score-Matched Analysis of the Gimema AML1718 and AML1310 Trials

Author

Piciocchi, Alfonso, primary, Messina, Monica, additional, Cipriani, Marta, additional, Paoloni, Francesca, additional, Simonetti, Giorgia, additional, Palmieri, Raffaele, additional, Marconi, Giovanni, additional, Buccisano, Francesco, additional, Fazi, Paola, additional, Vignetti, Marco, additional, Martinelli, Giovanni, additional, and Venditti, Adriano, additional

Published
2022
Full Text
View/download PDF

43. Gimema ALL2418: Interim Analysis of a Phase Iia Study of Feasibility and Effectiveness of Inotuzumab Ozogamicin in Adult Patients with B-Cell Acute Lymphoblastic Leukemia with Positive Minimal Residual Disease before Any Hematopoietic Stem Cell Transplantation

Author

Marconi, Giovanni, primary, Piciocchi, Alfonso, additional, Chiaretti, Sabina, additional, Papayannidis, Cristina, additional, Lunghi, Monia, additional, Salutari, Prassede, additional, Zappasodi, Patrizia, additional, Rambaldi, Alessandro, additional, Olivieri, Attilio, additional, Cavallari, Maurizio, additional, Soddu, Stefano, additional, Fracchiolla, Nicola S, additional, Gigli, Federica, additional, Cattaneo, Chiara, additional, Mattei, Daniele Giovanni, additional, Candoni, Anna, additional, Grillo, Giovanni, additional, Abbenante, Maria Chiara, additional, Audisio, Ernesta, additional, Bonifacio, Massimiliano, additional, Lico, Albana, additional, Lemoli, Roberto Massimo, additional, De Fabritiis, Paolo, additional, Ferrara, Felicetto, additional, Marino, Martina Rachele, additional, Messina, Monica, additional, Ferrari, Anna, additional, Robustelli, Valentina, additional, Nanni, Jacopo, additional, Della Starza, Irene, additional, Simonetti, Giorgia, additional, De Propris, Maria Stefania, additional, Bochicchio, Maria Teresa, additional, Vignetti, Marco, additional, Fazi, Paola, additional, and Martinelli, Giovanni, additional

Published
2022
Full Text
View/download PDF

44. Gimema AML1718 Part 1: Planned Interim Analysis of a Safety Run-in and Phase 2 Open-Label Study of Venetoclax, Fludarabine, Idarubicin and Cytarabine (V-FLAI) in the Induction Therapy of Non Low-Risk Acute Myeloid Leukemia

Author

Marconi, Giovanni, primary, Piciocchi, Alfonso, additional, Audisio, Ernesta, additional, Priolo, Giorgio, additional, Papayannidis, Cristina, additional, Martelli, Maurizio, additional, Paoloni, Francesca, additional, Lemoli, Roberto Massimo, additional, Bocchia, Monica, additional, Lanza, Francesco, additional, Lico, Albana, additional, Ciceri, Fabio, additional, Della Porta, Matteo G., additional, Frigeni, Marco, additional, Giaccone, Luisa, additional, Beltrami, Germana, additional, Borlenghi, Erika, additional, Di Chio, Maria Chiara, additional, Selleri, Carmine, additional, Crea, Enrico, additional, Urbino, Irene, additional, Sartor, Chiara, additional, Minotti, Clara, additional, Guolo, Fabio, additional, La Sala, Edoardo, additional, Nanni, Jacopo, additional, Simonetti, Giorgia, additional, Bochicchio, Maria Teresa, additional, Saglio, Giuseppe, additional, Venditti, Adriano, additional, Vignetti, Marco, additional, Fazi, Paola, additional, and Martinelli, Giovanni, additional

Published
2022
Full Text
View/download PDF

45. Safety and Tolerability of AZD0466 As Monotherapy for Patients with Advanced Hematological Malignancies. Preliminary Results from an Ongoing Phase I/II Trial

Author

Arslan, Shukaib, primary, Fleming, Shaun, additional, Jain, Nitin, additional, Martinelli, Giovanni, additional, Stein, Anthony S., additional, Blachly, James S., additional, Bajel, Ashish, additional, Curti, Antonio, additional, Marconi, Giovanni, additional, Fabbri, Giulia, additional, Marmor, Yotvat, additional, Sharma, Shringi, additional, Elgeioushi, Nairouz, additional, Couto-Francisco, Natalia, additional, Saeh, Jamal, additional, Tibes, Raoul, additional, Cader, Fathima Zumla, additional, and Konopleva, Marina, additional

Published
2022
Full Text
View/download PDF

46. Poster: AML-389 Phase 1/2 Study of SEL24/MEN1703, a First-in-Class Dual PIM/FLT3 Kinase Inhibitor, in Patients With IDH1/2-Mutated Acute Myeloid Leukemia: The DIAMOND-01 Trial

Author

Martinelli, Giovanni, primary, Santoro, Armando, additional, Gambacorti-Passerini, Carlo, additional, Polo, Susana Vives, additional, Solomon, Scott R., additional, Mukherjee, Sudipto, additional, Lech-Maranda, Ewa, additional, Levy, Moshe Yair, additional, Wierzbowska, Agnieszka, additional, Calbacho-Robles, María, additional, Marconi, Giovanni, additional, Giannini, Maria Benedetta, additional, Cano, Isabel, additional, Miñana, Laura Torres, additional, Acuña-Cruz, Evelyn, additional, Angelosanto, Noemi, additional, Mughal, Tariq I., additional, Galleu, Antonio, additional, Blotta, Simona, additional, Ravandi, Farhad, additional, and Montesinos, Pau, additional

Published
2022
Full Text
View/download PDF

47. Poster: AML-262 Pivekimab Sunirine (PVEK, IMGN632) Triplet With Azacitidine and Venetoclax Shows Broad Activity in Adverse Genetic Subsets of Relapsed/Refractory Acute Myeloid Leukemia and Reduced Infusion-Related Reactions

Author

Daver, Naval, primary, Montesinos, Pau, additional, Aribi, Ahmed, additional, Martinelli, Giovanni, additional, Altman, Jessica K., additional, Wang, Eunice S., additional, Roboz, Gail J., additional, Burke, Patrick W., additional, Gaidano, Gianluca, additional, Walter, Roland B., additional, Thomas, Xavier, additional, Jeyakumar, Deepa, additional, DeAngelo, Daniel J., additional, Erba, Harry P., additional, Todisco, Elisabetta, additional, Begna, Kebede, additional, Advani, Anjali, additional, Gastaud, Lauris, additional, de la Fuente, Adolfo, additional, Curti, Antonio, additional, Mendez, Lourdes M., additional, Vyas, Paresh, additional, Boissel, Nicolas, additional, Vey, Norbert, additional, Recher, Christian, additional, Longval, Thomas, additional, Platzbecker, Uwe, additional, Kapp-Schwörer, Silke, additional, Schliemann, Christoph, additional, Konopleva, Marina, additional, Torres, Laura, additional, Sallman, David A., additional, Marcucci, Guido, additional, Marconi, Giovanni, additional, Kantarjian, Hagop, additional, Sloss, Callum M., additional, Malcolm, Karen E., additional, Zweidler-McKay, Patrick A., additional, and Sweet, Kendra, additional

Published
2022
Full Text
View/download PDF

48. Targeting WEE1 to enhance conventional therapies for acute lymphoblastic leukemia

Author

Ghelli Luserna Di Rorà, Andrea, Beeharry, Neil, Imbrogno, Enrica, Ferrari, Anna, Robustelli, Valentina, Righi, Simona, Sabattini, Elena, Verga Falzacappa, Maria Vittoria, Ronchini, Chiara, Testoni, Nicoletta, Baldazzi, Carmen, Papayannidis, Cristina, Abbenante, Maria Chiara, Marconi, Giovanni, Paolini, Stefania, Parisi, Sarah, Sartor, Chiara, Fontana, Maria Chiara, De Matteis, Serena, Iacobucci, Ilaria, Pelicci, Pier Giuseppe, Cavo, Michele, Yen, Timothy J., and Martinelli, Giovanni

Published
2018
Full Text
View/download PDF

49. Prevalence and Prognostic Role of IDH Mutations in Acute Myeloid Leukemia: Results of the GIMEMA AML1516 Protocol

Author

Messina, Monica, primary, Piciocchi, Alfonso, additional, Ottone, Tiziana, additional, Paolini, Stefania, additional, Papayannidis, Cristina, additional, Lessi, Federica, additional, Fracchiolla, Nicola Stefano, additional, Forghieri, Fabio, additional, Candoni, Anna, additional, Mengarelli, Andrea, additional, Martelli, Maria Paola, additional, Venditti, Adriano, additional, Carella, Angelo Michele, additional, Albano, Francesco, additional, Mancini, Valentina, additional, Massimo, Bernardi, additional, Arena, Valentina, additional, Sargentini, Valeria, additional, Sciumè, Mariarita, additional, Pastore, Domenico, additional, Todisco, Elisabetta, additional, Roti, Giovanni, additional, Siragusa, Sergio, additional, Ladetto, Marco, additional, Pravato, Stefano, additional, De Bellis, Eleonora, additional, Simonetti, Giorgia, additional, Marconi, Giovanni, additional, Cerchione, Claudio, additional, Fazi, Paola, additional, Vignetti, Marco, additional, Amadori, Sergio, additional, Martinelli, Giovanni, additional, and Voso, Maria Teresa, additional

Published
2022
Full Text
View/download PDF

50. Abstract 3001: Targeting autophagy in acute lymphoblastic leukemia: Synergism between ponatinib, hydroxychloroquine and rapamycin

Author

Rora, Andrea Ghelli Luserna Di, primary, Fonzi, Eugenio, additional, Ledda, Lorenzo, additional, Napolitano, Roberta, additional, Ferrari, Anna, additional, Padella, Antonella, additional, Ghetti, Martina, additional, Bochicchio, Maria Teresa, additional, Jandoubi, Mouna, additional, Mazzotti, Cristina, additional, Paganelli, Matteo, additional, Cerchione, Claudio, additional, Marconi, Giovanni, additional, Musuraca, Gerardo, additional, Martinelli, Giovanni, additional, and Simonetti, Giorgia, additional

Published
2022
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results