1. Frequency of five cardiovascular/hemostatic entities as primary manifestations of SARS-CoV-2 infection: Results of the UMC-19-S2
- Author
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Òscar Miró, Pere Llorens, Sònia Jiménez, Pascual Piñera, Guillermo Burillo-Putze, Alfonso Martín, Francisco Javier Martín-Sánchez, Juan González del Castillo, Pascual Piñera Salmerón, Fahd Beddar Chaib, Enrique del Hoyo Peláez, Belén Rodríguez Miranda, Alejandra Sánchez Arias, Noemí Ruiz de Lobera, Marta Iglesias Vela, Laura Hernando López, Carmen del Arco Galán, Guillermo Fernández Jiménez, E. Jorge García Lamberechts, Marcos Fragiel, María Jesús Domínguez, María Eugenia Barrero Ramos, José María Ferreras Amez, Belén Arribas Entrala, Ángel García García, Marta Fuentes de Frutos, Ricardo Calvo López, Javier Jacob-Rodríguez, Ferrán Llopis-Roca, María Carmen Ponce, Napoleón Meléndez, María José Fortuny Bayarri, Francisco José Salvador Suárez, María Luisa López Grima, Mª. Ángeles Juan Gómez, Javier Millán, José A. Sánchez Nicolás, Paula Lázaro Aragües, Francisco Javier Lucas-Imbernón, Francisco Javier Lucas-Galán, Blas Jiménez, Rigoberto del Río, Lluís LLauger García, Begoña Espinosa, Ana Belén Payá, Juan Miguel Porrino, María Rosales Maestre, María José Cano Cano, Rosa Sorando Serra, Carlos Cardozo, Juan José López Díaz, Martín Ruiz Grinspan, Cristóbal M. Rodríguez Leal, Sara Gayoso Martín, Silvia Ortiz Zamorano, María Pilar López Díaz, Carmen Agüera Urbano, Elisa Delgado Padial, Ana Peiró Gómez, Elena Gonzalo Bellver, Laura Ejarque Martínez, Maribel Marzo Lambíes, José Noceda, José Vicente Brasó Aznar, José Luis Ruiz López, Alfons Aguirre Tejedo, Isabel Cirera Lorenzo, Alejandro Martín Quirós, Elena Muñoz del Val, Enrique Martín Mojarro, Brigitte Silvana Alarcón Jiménez, Virginia Carbajosa, Susana Sánchez Ramón, Matilde González Tejera, Pablo Herrero Puente, Desire María Velarde Herrera, Francisco Javier Teigell Muñoz, Juan Carlos Repáraz González, Félix González Martínez, Diana Moya Olmeda, Anna Palau, Patricia Eiroa Hernández, Marcos Expósito Rodríguez, Nieves López Laguna, María García-Uría, Josep Guardiola, Polo Higa Sansome, María José Marchena González, EissaJaloud Saavedra, María Adroher, Ester Soy Ferrer, Arturo Huertas, Raquel Torres Gárate, Beatriz Valle Borrego, Josep María MòdolDeltell, Samuel Olmos Soto, Elena Díaz Fernández, José Pavón Monzo, Nayra Cabrera González, Ricardo Juárez, Jorge Pedraza García, Manuel Salido, Miguel Moreno Fernández, Carles Pérez, María Teresa Maza Vera, Raquel Rodríguez Calveiro, Josep Tost, Antonio Barceló, Rosario Carrió, and Eva Quero Moto
- Subjects
Male ,medicine.medical_specialty ,Acute coronary syndrome ,Population ,030204 cardiovascular system & hematology ,Malalties vasculars ,Hemostàtics ,Hemostatics ,03 medical and health sciences ,0302 clinical medicine ,Internal medicine ,medicine ,Humans ,030212 general & internal medicine ,Acute Coronary Syndrome ,education ,Vascular diseases ,Stroke ,Aged ,Retrospective Studies ,Aged, 80 and over ,Venous Thrombosis ,Hemostasis ,education.field_of_study ,Malalties cardiovasculars ,SARS-CoV-2 ,business.industry ,Case-control study ,COVID-19 ,Retrospective cohort study ,Middle Aged ,medicine.disease ,Pulmonary embolism ,Venous thrombosis ,Cardiovascular Diseases ,Case-Control Studies ,Female ,Upper gastrointestinal bleeding ,Gastrointestinal Hemorrhage ,Pulmonary Embolism ,Cardiology and Cardiovascular Medicine ,business - Abstract
• Several cardiovascular/hemostatic disturbances haves been reported in patients with COVID-19, but the real frequency and their potential association with the pathogenic mechanisms of SARS-CoV-19 still remain to be defined. • We investigated the relative frequency of acute coronary syndrome, deep venous thrombosis, pulmonary embolism, stroke and upper gastrointestinal bleeding in COVID patents attending emergency departments (EDs), before hospitalization and compared them with frequencies in the general ED population attending 50 Spanish EDs. • We found that the risk of pulmonary embolism is clearly increased in COVID patients, with an OR of 4.53 with respect to non-COVID patients (95% confidence interval 4.03- 5.10). Additionally, the diagnosis of pulmonary embolism was 2 fold more frequent among ED comers in 2020 compared to 2019, suggesting a SARS-CoV-2 role in such increment of cases.. The remaining entities studied were not found to be unequivocally increased in the present study and need further investigation.
- Published
- 2021
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