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3. Acaricidal activity of synthesized titanium dioxide nanoparticles using Calotropis gigantea against Rhipicephalus microplus and Haemaphysalis bispinosa

Author

Marimuthu, Sampath, Rahuman, Abdul Abdul, Jayaseelan, Chidambaram, Kirthi, Arivarasan Vishnu, Santhoshkumar, Thirunavukkarasu, Velayutham, Kanayairam, Bagavan, Asokan, Kamaraj, Chinnaperumal, Elango, Gandhi, Iyappan, Moorthy, Siva, Chinnadurai, Karthik, Loganathan, and Rao, Kokati Venkata Bhaskara

Published
2013
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5. Novel and simple approach using synthesized nickel nanoparticles to control blood-sucking parasites

Author

Rajakumar, Govindasamy, Rahuman, Abdul Abdul, Velayutham, Kanayairam, Ramyadevi, Jeyaraman, Jeyasubramanian, Kadarkaraithangam, Marikani, Arumugam, Elango, Gandhi, Kamaraj, Chinnaperumal, Santhoshkumar, Thirunavukkarasu, Marimuthu, Sampath, Zahir, Abdul Abduz, Bagavan, Asokan, Jayaseelan, Chidambaram, Kirthi, Arivarasan Vishnu, Iyappan, Moorthy, and Siva, Chinnadurai

Published
2013
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6. Evaluation of stem aqueous extract and synthesized silver nanoparticles using Cissus quadrangularis against Hippobosca maculata and Rhipicephalus (Boophilus) microplus

Author

Santhoshkumar, Thirunavukkarasu, Rahuman, Abdul Abdul, Bagavan, Asokan, Marimuthu, Sampath, Jayaseelan, Chidambaram, Kirthi, Arivarasan Vishnu, Kamaraj, Chinnaperumal, Rajakumar, Govindasamy, Zahir, Abdul Abduz, Elango, Gandhi, Velayutham, Kanayairam, Iyappan, Moorthy, Siva, Chinnadurai, Karthik, Loganathan, and Rao, Kokati Venkata Bhaskara

Published
2012
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10. Solanum trilobatum extract-mediated synthesis of titanium dioxide nanoparticles to control Pediculus humanus capitis, Hyalomma anatolicum anatolicum and Anopheles subpictus

Author

Rajakumar, Govindasamy, Rahuman, Abdul Abdul, Jayaseelan, Chidambaram, Santhoshkumar, Thirunavukkarasu, Marimuthu, Sampath, Kamaraj, Chinnaperumal, Bagavan, Asokan, Zahir, Abdul Abduz, Kirthi, Arivarasan Vishnu, Elango, Gandhi, Arora, Pooja, Karthikeyan, Rajan, Manikandan, Sivan, and Jose, Sujin

Published
2014
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30. Green synthesis of copper nanoparticles using Eclipta prostrata leaves extract and their antioxidant and cytotoxic activities.

Author

ILL-MIN CHUNG, RAHUMAN, ABDUL ABDUL, MARIMUTHU, SAMPATH, KIRTHI, ARIVARASAN VISHNU, ANBARASAN, KARUNANITHI, PADMINI, PARTHASARATHY, and RAJAKUMAR, GOVINDASAMY

Subjects
NANOPARTICLES, COPPER ions, FOURIER transform infrared spectroscopy, BIOMOLECULES, MOLECULAR biology
Abstract

The present study outlines the development of a method to synthesize copper nanoparticles (CuNPs) by mixing copper acetate solution with leaf extract of Eclipta prostrata without using any surfactant or external energy. E. prostrata leaf extract function as an excellent reducing agent of copper ions, and the biosynthesized CuNPs are safer for the environment. The powder X-ray diffraction (XRD) pattern provided evidence for the formation of face-centered cubic structure ranging from 23 to 57 nm, with an average size of 31±1.2 nm. Fourier transform infrared spectroscopy (FTIR) was used to identify the biomolecules and capping reagents in the E. prostrata leaf extract that may be responsible for the reduction of copper ions and the stability of the bioreduced nanoparticles. The biosynthesized CuNPs displayed considerable antioxidant capacity. Similarly, in vitro anticancer studies demonstrated the cytotoxicity value of synthesized CuNPs against tested HepG2 cells. The findings of the present study suggested that biosynthesized CuNPs that utilize extracts of E. prostrata may be used for therapeutic application, and thus are a promising nanomaterial. [ABSTRACT FROM AUTHOR]

Published
2017
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31. Evaluation of antiplasmodial activity of medicinal plants from North Indian Buchpora and South Indian Eastern Ghats

Author

Kaushik, Naveen K, primary, Bagavan, Asokan, additional, Rahuman, Abdul A, additional, Zahir, Abdul A, additional, Kamaraj, Chinnaperumal, additional, Elango, Gandhi, additional, Jayaseelan, Chidambaram, additional, Kirthi, Arivarasan V, additional, Santhoshkumar, Thirunavukkarasu, additional, Marimuthu, Sampath, additional, Rajakumar, Govindasamy, additional, Tiwari, Santosh K, additional, and Sahal, Dinkar, additional

Published
2015
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32. Solanum trilobatum extract-mediated synthesis of titanium dioxide nanoparticles to control Pediculus humanus capitis, Hyalomma anatolicum anatolicum and Anopheles subpictus

Author

Rajakumar, Govindasamy, primary, Rahuman, Abdul Abdul, additional, Jayaseelan, Chidambaram, additional, Santhoshkumar, Thirunavukkarasu, additional, Marimuthu, Sampath, additional, Kamaraj, Chinnaperumal, additional, Bagavan, Asokan, additional, Zahir, Abdul Abduz, additional, Kirthi, Arivarasan Vishnu, additional, Elango, Gandhi, additional, Arora, Pooja, additional, Karthikeyan, Rajan, additional, Manikandan, Sivan, additional, and Jose, Sujin, additional

Published
2013
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33. Antimalarial activities of medicinal plants traditionally used in the villages of Dharmapuri regions of South India

Author

Kamaraj, Chinnaperumal, primary, Kaushik, Naveen Kumar, additional, Rahuman, Abdul Abdul, additional, Mohanakrishnan, Dinesh, additional, Bagavan, Asokan, additional, Elango, Gandhi, additional, Zahir, Abdul Abduz, additional, Santhoshkumar, Thirunavukkarasu, additional, Marimuthu, Sampath, additional, Jayaseelan, Chidambaram, additional, Kirthi, Arivarasan Vishnu, additional, Rajakumar, Govindasamy, additional, Velayutham, Kanayairam, additional, and Sahal, Dinkar, additional

Published
2012
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34. Lousicidal activity of synthesized silver nanoparticles using Lawsonia inermis leaf aqueous extract against Pediculus humanus capitis and Bovicola ovis

Author

Marimuthu, Sampath, primary, Rahuman, Abdul Abdul, additional, Santhoshkumar, Thirunavukkarasu, additional, Jayaseelan, Chidambaram, additional, Kirthi, Arivarasan Vishnu, additional, Bagavan, Asokan, additional, Kamaraj, Chinnaperumal, additional, Elango, Gandhi, additional, Zahir, Abdul Abduz, additional, Rajakumar, Govindasamy, additional, and Velayutham, Kanayairam, additional

Published
2011
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35. Evaluation of Catharanthus roseus leaf extract-mediated biosynthesis of titanium dioxide nanoparticles against Hippobosca maculata and Bovicola ovis

Author

Velayutham, Kanayairam, primary, Rahuman, Abdul Abdul, additional, Rajakumar, Govindasamy, additional, Santhoshkumar, Thirunavukkarasu, additional, Marimuthu, Sampath, additional, Jayaseelan, Chidambaram, additional, Bagavan, Asokan, additional, Kirthi, Arivarasan Vishnu, additional, Kamaraj, Chinnaperumal, additional, Zahir, Abdul Abduz, additional, and Elango, Gandhi, additional

Published
2011
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36. Efficacy of adulticidal and larvicidal properties of botanical extracts against Haemaphysalis bispinosa, Hippobosca maculata, and Anopheles subpictus

Author

Santhoshkumar, Thirunavukkarasu, primary, Rahuman, Abdul Abdul, additional, Bagavan, Asokan, additional, Kirthi, Arivarasan Vishnu, additional, Marimuthu, Sampath, additional, Jayaseelan, Chidambaram, additional, Kamaraj, Chinnaperumal, additional, Zahir, Abdul Abduz, additional, Elango, Gandhi, additional, Rajakumar, Govindasamy, additional, and Velayutham, Kanayairam, additional

Published
2011
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37. Efficacy of plant-mediated synthesized silver nanoparticles against hematophagous parasites

Author

Jayaseelan, Chidambaram, primary, Rahuman, Abdul Abdul, additional, Rajakumar, Govindasamy, additional, Santhoshkumar, Thirunavukkarasu, additional, Kirthi, Arivarasan Vishnu, additional, Marimuthu, Sampath, additional, Bagavan, Asokan, additional, Kamaraj, Chinnaperumal, additional, Zahir, Abdul Abduz, additional, Elango, Gandhi, additional, Velayutham, Kanayairam, additional, Rao, Kokati Venkata Bhaskara, additional, Karthik, Loganathan, additional, and Raveendran, Sankariah, additional

Published
2011
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38. Evaluation of green synthesized silver nanoparticles against parasites

Author

Marimuthu, Sampath, primary, Rahuman, Abdul Abdul, additional, Rajakumar, Govindasamy, additional, Santhoshkumar, Thirunavukkarasu, additional, Kirthi, Arivarasan Vishnu, additional, Jayaseelan, Chidambaram, additional, Bagavan, Asokan, additional, Zahir, Abdul Abduz, additional, Elango, Gandhi, additional, and Kamaraj, Chinnaperumal, additional

Published
2010
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39. Synthesis of silver nanoparticles using Nelumbo nucifera leaf extract and its larvicidal activity against malaria and filariasis vectors

Author

Santhoshkumar, Thirunavukkarasu, primary, Rahuman, Abdul Abdul, additional, Rajakumar, Govindasamy, additional, Marimuthu, Sampath, additional, Bagavan, Asokan, additional, Jayaseelan, Chidambaram, additional, Zahir, Abdul Abduz, additional, Elango, Gandhi, additional, and Kamaraj, Chinnaperumal, additional

Published
2010
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41. An Investigation of the Cytotoxicity and Caspase-Mediated Apoptotic Effect of Green Synthesized Zinc Oxide Nanoparticle Using Eclipta prostrata on Human Liver Carcinoma Cells.

Author

Ill-Min Chung, Rahuman, Abdul Abdul, Marimuthu, Sampath, Kirthi, Arivarasan Vishnu, Anbarasan, Karunanithi, and Rajakumar, Govindasamy

Subjects
ZINC oxide synthesis, ANTINEOPLASTIC agents, APOPTOSIS
Abstract

Cancer is a leading cause of death worldwide and sustained focus is on the discovery and development of newer and better tolerated anticancer drugs, especially from plants. In the present study, a simple, eco-friendly, and inexpensive approach was followed for the synthesis of zinc oxide nanoparticles (ZnO NPs) using the aqueous leaf extract of Eclipta prostrata. The synthesized ZnO NPs were characterized by UV-visible absorption spectroscopy, X-ray diffraction (XRD), Fourier transform infrared spectroscopy (FTIR), Scanning electron microscopy with energy dispersive X-ray spectroscopy (SEM-EDX), High-resolution transmission electron microscopy (HRTEM), and Selected area (electron) diffraction (SAED). The HRTEM images confirmed the presence of triangle, radial, hexagonal, rod, and rectangle, shaped with an average size of 29 ± 1.3 nm. The functional groups for synthesized ZnO NPs were 3852 cm-1 for H-H weak peak, 3138 cm-1 for aromatic C-H extend, and 1648 cm-1 for Aromatic ring stretch. The 3-(4,5-Dimethylthiazol-2-yl)-2,5-Diphenyltetrazolium Bromide (MTT), caspase and DNA fragmentation assays were carried out using various concentrations of ZnO NPs ranging from 1 to 100 mg/mL. The synthesized ZnO NPs showed dose dependent cytopathic effects in the Hep-G2 cell line. At 100 mg/mL concentration, the synthesized ZnO NPs exhibited significant cytotoxic effects and the apoptotic features were confirmed through caspase-3 activation and DNA fragmentation assays. [ABSTRACT FROM AUTHOR]

Published
2015
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42. Eco-friendly microbial route to synthesize cobalt nanoparticles using Bacillus thuringiensis against malaria and dengue vectors.

Author

Marimuthu, Sampath, Rahuman, Abdul Abdul, Kirthi, Arivarasan Vishnu, Santhoshkumar, Thirunavukkarasu, Jayaseelan, Chidambaram, and Rajakumar, Govindasamy

Subjects
BACILLUS thuringiensis, NANOPARTICLES, DISEASE vectors, CHEMICAL synthesis, SCANNING electron microscopy, FOURIER transform infrared spectroscopy
Abstract

The developments of resistance and persistence to chemical insecticides and concerns about the non-target effects have prompted the development of eco-friendly mosquito control agents. The aim of this study was to investigate the larvicidal activities of synthesized cobalt nanoparticles (Co NPs) using bio control agent, Bacillus thuringiensis against malaria vector, Anopheles subpictus and dengue vector, Aedes aegypti (Diptera: Culicidae). The synthesized Co NPs were characterized by X-ray diffraction (XRD), Fourier transform infrared (FTIR), Field-emission scanning electron microscopy (FESEM) with energy dispersive X-ray spectroscopy, and Transmission electron microscopy (TEM). XRD analysis showed three distinct diffraction peaks at 27.03°, 31.00°, and 45.58° indexed to the planes 102, 122, and 024, respectively on the face-centered cubic cobalt acetate with an average size of 85.3 nm. FTIR spectra implicated role of the peak at 3,436 cm −1 for O–H hydroxyl group, 2924 cm −1 for methylene C–H stretch in the formation of Co NPs. FESEM analysis showed the topological and morphological appearance of NPs which were found to be spherical and oval in shape. TEM analysis showed polydispersed and clustered NPs with an average size of 84.81 nm. The maximum larvicidal mortality was observed in the cobalt acetate solution, B. thuringiensis formulation, and synthesized Co NPs against fourth instar larvae of A. subpictus and A. aegypti with LC 50 values of 29.16, 8.12, 3.59 mg/L; 34.61, 6.94, and 2.87 mg/L; r2 values of 0.986, 0.933, 0.942; 0.962, 0.957, and 0.922, respectively. [ABSTRACT FROM AUTHOR]

Published
2013
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43. Green synthesis of copper nanoparticles using Eclipta prostrata leaves extract and their antioxidant and cytotoxic activities.

Author

Chung IM, Abdul Rahuman A, Marimuthu S, Kirthi AV, Anbarasan K, Padmini P, and Rajakumar G

Abstract

The present study outlines the development of a method to synthesize copper nanoparticles (CuNPs) by mixing copper acetate solution with leaf extract of Eclipta prostrata without using any surfactant or external energy. E. prostrata leaf extract function as an excellent reducing agent of copper ions, and the biosynthesized CuNPs are safer for the environment. The powder X-ray diffraction (XRD) pattern provided evidence for the formation of face-centered cubic structure ranging from 23 to 57 nm, with an average size of 31±1.2 nm. Fourier transform infrared spectroscopy (FTIR) was used to identify the biomolecules and capping reagents in the E. prostrata leaf extract that may be responsible for the reduction of copper ions and the stability of the bioreduced nanoparticles. The biosynthesized CuNPs displayed considerable antioxidant capacity. Similarly, in vitro anticancer studies demonstrated the cytotoxicity value of synthesized CuNPs against tested HepG2 cells. The findings of the present study suggested that biosynthesized CuNPs that utilize extracts of E. prostrata may be used for therapeutic application, and thus are a promising nanomaterial.

Published
2017
Full Text
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