1. Increased oxygen extraction and mitochondrial protein expression after small muscle mass endurance training
- Author
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Jose A. L. Calbet, Carlo Capelli, Jostein Hallén, Øyvind Skattebo, Marius Auensen, and Bjarne Rud
- Subjects
Arteriovenous oxygen difference ,Blood flow ,Endurance training ,Fick method ,Limitations ,Maximal oxygen uptake ,Muscle oxygen diffusion ,Peripheral adaptations ,Adult ,medicine.medical_specialty ,Physical Therapy, Sports Therapy and Rehabilitation ,Citrate (si)-Synthase ,030204 cardiovascular system & hematology ,Muscle mass ,Quadriceps Muscle ,Mitochondrial Proteins ,Young Adult ,03 medical and health sciences ,Oxygen Consumption ,0302 clinical medicine ,Internal medicine ,medicine ,Humans ,Citrate synthase ,Orthopedics and Sports Medicine ,biology ,Chemistry ,Extraction (chemistry) ,VO2 max ,030229 sport sciences ,Mitochondria, Muscle ,Endurance Training ,Endocrinology ,Regional Blood Flow ,biology.protein - Abstract
When exercising with a small muscle mass, the mass-specific O2 delivery exceeds the muscle oxidative capacity resulting in a lower O2 extraction compared with whole-body exercise. We elevated the muscle oxidative capacity and tested its impact on O2 extraction during small muscle mass exercise. Nine individuals conducted six weeks of one-legged knee extension (1L-KE) endurance training. After training, the trained leg (TL) displayed 45% higher citrate synthase and COX-IV protein content in vastus lateralis and 15%-22% higher pulmonary oxygen uptake ( V˙O2peak ) and peak power output ( W˙peak ) during 1L-KE than the control leg (CON; all P
- Published
- 2020
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