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3. Efficacy and safety of an early oral switch in low-risk Staphylococcus aureus bloodstream infection (SABATO): an international, open-label, parallel-group, randomised, controlled, non-inferiority trial

Author

Valiente, Adoración, de Cueto, Marina, Rodríguez, Ángel, Molina, José, Fischer, Julia, Paul, Gregor, Gallien, Sébastien, Fihman, Vincent, Lacasse, Marion, Coustillères, Francois, Becker, Christian, Fuchs, André, Morata, Laura, Weis, Sebastian, Ponscarme, Diane, Khatchatourian, Lydie, Rouveix, Elisabeth, Merrien, Dominique, Lecomte, Raphaël, Veenemans, Jacobien, Vilchez, Helem H., Kessel, Johanna, Bonten, Marc J.M., Rupp, Jan, Hocqueloux, Laurent, Lucht, Frederic, Stahl, Jean-Paul, Vlek, Anne, Prinz-Langenohl, Reinhild, Tolsma, Violaine, Kaasch, Achim J, López-Cortés, Luis Eduardo, Rodríguez-Baño, Jesús, Cisneros, José Miguel, Dolores Navarro, M, Fätkenheuer, Gerd, Jung, Norma, Rieg, Siegbert, Lepeule, Raphaël, Coutte, Laetitia, Bernard, Louis, Lemaignen, Adrien, Kösters, Katrin, MacKenzie, Colin R, Soriano, Alex, Hagel, Stefan, Fantin, Bruno, Lafaurie, Matthieu, Talarmin, Jean-Philippe, Dinh, Aurélien, Guimard, Thomas, Boutoille, David, Welte, Tobias, Reuter, Stefan, Kluytmans, Jan, Martin, Maria Luisa, Forestier, Emmanuel, Stocker, Hartmut, Vitrat, Virginie, Tattevin, Pierre, Rommerskirchen, Anna, Noret, Marion, Adams, Anne, Kern, Winfried V, Hellmich, Martin, and Seifert, Harald

Published
2024
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14. Dynamic Adhesive Behavior and Biofilm Formation of Staphylococcus aureus on Polylactic Acid Surfaces in Diabetic Environments.

Author

Fernández-Grajera, María, Pacha-Olivenza, Miguel A., Fernández-Calderón, María Coronada, González-Martín, María Luisa, and Gallardo-Moreno, Amparo M.

Subjects
POLYLACTIC acid, BIOABSORBABLE implants, BIOFILMS, KETONES, ARTIFICIAL implants, BACTERIAL adhesion
Abstract

Interest in biodegradable implants has focused attention on the resorbable polymer polylactic acid. However, the risk of these materials promoting infection, especially in patients with existing pathologies, needs to be monitored. The enrichment of a bacterial adhesion medium with compounds that are associated with human pathologies can help in understanding how these components affect the development of infectious processes. Specifically, this work evaluates the influence of glucose and ketone bodies (in a diabetic context) on the adhesion dynamics of S. aureus to the biomaterial polylactic acid, employing different approaches and discussing the results based on the physical properties of the bacterial surface and its metabolic activity. The combination of ketoacidosis and hyperglycemia (GK2) appears to be the worst scenario: this system promotes a state of continuous bacterial colonization over time, suppressing the stationary phase of adhesion and strengthening the attachment of bacteria to the surface. In addition, these supplements cause a significant increase in the metabolic activity of the bacteria. Compared to non-enriched media, biofilm formation doubles under ketoacidosis conditions, while in the planktonic state, it is glucose that triggers metabolic activity, which is practically suppressed when only ketone components are present. Both information must be complementary to understand what can happen in a real system, where planktonic bacteria are the ones that initially colonize a surface, and, subsequently, these attached bacteria end up forming a biofilm. This information highlights the need for good monitoring of diabetic patients, especially if they use an implanted device made of PLA. [ABSTRACT FROM AUTHOR]

Published
2024
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16. Sociodemographic, clinical, and immunological factors associated with SARS-CoV-2 diagnosis and severe COVID-19 outcomes in people living with HIV: a retrospective cohort study

Author

Muntada, Esteve, Esteve, Anna, Riera, Melchor, Navarro, Gemma, Knobel, Hernando, Mallolas, Josep, Podzamczer, Daniel, Curran, Adrià, Burgos, Joaquín, Mateo, Maria Gracia, Gutierrez, Maria del Mar, Murillas, Javier, Homar, Francisco, Fernández-Montero, Jose Vicente, González, Eva, Peraire, Joaquim, Vidal, Francesc, Leon, Elena, Masabeu, Àngels, Orti, Amat-Joaquim, Dalmau, David, Jaen, Àngels, Deig, Elisabet, De Lazzari, Elisa, Berrocal, Leire, Fernandez, Guillem, Rodríguez, Lucía, Gargoulas, Freya, Vanrell, Toni, Rubia, Jose Carlos, Vilà, Josep, Martínez, Marina, Morell, Bibiana, Tamayo, Maribel, Palacio, Jorge, Ambrosioni, Juan, Laguno, Montse, Martínez-Rebollar, María, Blanco, José Luis, Garcia, Felipe, Martínez, Esteban, Torres, Berta, de la Mora, Lorena, Inciarte, Alexy, Ugarte, Ainoa, Chivite, Iván, González-Cordon, Ana, Leal, Lorna, Jou, Antoni, Saumoy, Maria, Silva, Ana, Scévola, Sofia, Navarro, Jordi, Suanzes, Paula, Mur, Isabel, Ribas, Maria Àngels, Campins, Antoni A, Fanjul, Francisco, Leyes, María, Peñaranda, María, Martin, María Luisa, Vilchez, Helem Haydee, Calzado, Sònia, Cervantes, Manel, Amengual, M. José, Navarro, Marta, Payeras, Antoni, Cifuentes, Carmen, Villoslada, Aroa, Sorní, Patrícia, Molero, Marta, Abdulghani, Nadia, Comella, Thaïs, Sola, Rocio, Vargas, Montserrat, Viladés, Consuleo, Martí, Anna, Barrufet, Pilar, Arbones, Laia, Chamarro, Elena, Cairó, Mireia, Martinez-Lacas, Xavier, Font, Roser, Macorigh, Lizza, Nomah, Daniel K, Reyes-Urueña, Juliana, Díaz, Yesika, Moreno, Sergio, Aceiton, Jordi, Bruguera, Andreu, Vivanco-Hidalgo, Rosa M, Llibre, Josep M, Domingo, Pere, Falcó, Vicenç, Imaz, Arkaitz, Cortés, Cristina, Force, Lluís, Letang, Emili, Vilaró, Ingrid, Casabona, Jordi, and Miro, Jose M

Published
2021
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19. Magnetic Nanoparticles as MRI Contrast Agents

Author

Avasthi, Ashish, Caro, Carlos, Pozo‑Torres, Esther, Leal, Manuel Pernia, García‑Martín, María Luisa, Olivucci, Massimo, Editor-in-Chief, Wong, Wai-Yeung, Editor-in-Chief, Bayley, Hagan, Series Editor, Hughes, Greg, Series Editor, Hunter, Christopher A., Series Editor, Hwang, Seong-Ju, Series Editor, Ishihara, Kazuaki, Series Editor, Kirchner, Barbara, Series Editor, Krische, Michael J., Series Editor, Larsen, Delmar, Series Editor, Lehn, Jean-Marie, Series Editor, Luque, Rafael, Series Editor, Siegel, Jay S., Series Editor, Thiem, Joachim, Series Editor, Venturi, Margherita, Series Editor, Wong, Chi-Huey, Series Editor, Wong, Henry N.C., Series Editor, Yam, Vivian Wing-Wah, Series Editor, Yan, Chunhua, Series Editor, You, Shu-Li, Series Editor, Puente-Santiago, Alain R., editor, and Rodríguez-Padrón, Daily, editor

Published
2020
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20. Use and Safety of Remdesivir in Kidney Transplant Recipients With COVID-19

Author

Buxeda, Anna, Arias-Cabrales, Carlos, Pérez-Sáez, María José, Cacho, Judit, Cabello Pelegrin, Sheila, Melilli, Edoardo, Aladrén, María José, Galeano, Cristina, Lorenzo, Inmaculada, Mazuecos, Auxiliadora, Saura, Isabel María, Franco, Antonio, Ruiz-Fuentes, María del Carmen, Sánchez-Cámara, Luis Alberto, Siverio, Orlando, Martin, María Luisa, González-García, Elena, López, Verónica, Martin-Moreno, Paloma Leticia, Moina, Iñigo, Moral Berrio, Esperanza, Moreso, Francesc, Portolés, José María, Santana-Estupiñán, Raquel, Zárraga, Sofía, Canal, Cristina, Sánchez-Álvarez, Emilio, Pascual, Julio, and Crespo, Marta

Published
2021
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23. Nurses’ perceptions and demands regarding COVID-19 care delivery in critical care units and hospital emergency services

Author

González-Gil, María Teresa, González-Blázquez, Cristina, Parro-Moreno, Ana Isabel, Pedraz-Marcos, Azucena, Palmar-Santos, Ana, Otero-García, Laura, Navarta-Sánchez, María Victoria, Alcolea-Cosín, María Teresa, Argüello-López, María Teresa, Canalejas-Pérez, Coro, Carrillo-Camacho, María Elena, Casillas-Santana, María Lourdes, Díaz-Martínez, María Luisa, García-González, Asunción, García-Perea, Eva, Martínez-Marcos, Mercedes, Martínez-Martín, María Luisa, Palazuelos-Puerta, María del Pilar, Sellán-Soto, Carmen, and Oter-Quintana, Cristina

Published
2021
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25. Effects of first-line antiretroviral therapy on the CD4/CD8 ratio and CD8 cell counts in CoRIS: a prospective multicentre cohort study

Author

Jarrin, Inmaculada, Moreno, Santiago, Alejos, Belén, Muñoz-Fernández, MÁngeles, Consuegra, Irene, Merino, Esperanza, García, Gema, Lirola, Ana López, García, Dácil, Asensi, Víctor, Valle, Eulalia, Rubio, Rafael, Pulido, Federico, Iribarren, José Antonio, Arrizabalaga, Julio, Gutiérrez, Félix, Masiá, Mar, Muga, Roberto, Sanvisens, Arantza, Berenguer, Juan, Vidal, Francesc, Montero, Marta, Blanco, José Ramón, López Bernarlo de Quirós, Juan Carlos, González-Garcia, Juan, Peraire, Joaquín, Arazo, Piedad, López-Aldeguer, José, Dalmau, David, Arnalich, Francisco, Rivero, Maria, Oteo, José Antonio, Sampériz, Gloria, Amengual, María José, Jaén, Angels, de los Santos, Ignacio, Repáraz, Jesús, Navarro, Gemma, Bernal, Enrique, Sanz, Jesús, Viciana, Pompeyo, García, Federico, Casado, José Luis, Del Romero, Jorge, Cano, Alfredo, Antela, Antonio, Quero, José Hernández, Riera, Melchor, Raposo, Montserrat, Santos, Jesús, Losada, Elena, Daniel, Podzamczer, Peñaranda, María, Ayerbe, Cristina Gómez, Espinosa, Nuria, Olalla, Julián, Imaz, Arkaitz, Martínez, Onofre, Curran, Adrian, Castro, Ángeles, Pérez Stachowski, Javier, Muñoz, Josefa, Vera, Francisco Jesús, Galera, Carlos, Pernas, Berta, Amador, Concha, Zuriñe, Miren, Albendin, Helena, Suárez-García, Inés, Pasquau, Francisco, Omar, Mohamed, Malmierca, Eduardo, de Zarraga, Miguel Alberto, Gómez Vidal, María Amparo, Estrada, Vicente, Górgolas, Miguel, Sanz, José, Téllez, María Jesús, Galindo, María José, Cabello, Alfonso, Rivero, Antonio, Arranz, Alberto, Cervero, Miguel, Vilalta, Ramón, Pineda, Juan A, Rivero-Juárez, Antonio, Torres, Rafael, Poveda, Eva, Rincón, Pilar, Pérez, Alexandre, Moreno, Cristina, Portilla, Irene, Díaz-Flores, Felicitas, Rivas, María E, Bisbal, Otilia, Aramburu, María J, Padilla, Sergio, Fuster, Daniel, Gutiérrez, Isabel, Viladés, Consuelo, Blanes, Marino, Arribas, José Ramón, Ibarra, Valvanera, Sanmartí, Montse, de Alda, María Ruiz, Cervantes, Manel, Salas, Ana, Dronda, Fernando, Alcaraz, Antonia, Muñoz, Leopoldo, Rodríguez, Carmen, Ribas, María Angels, Viciana, Isabel, López-Cortés, Luis, Tiraboschi, Juan, del Arco, Alfonso, Martínez, Lorena, Mena, Álvaro, Mirena, Josu, Pérez, Aurora, Ena, Javier, González-Ruano, Patricia, Vergas, Jorge, Álvarez, Beatriz, Hernández, Cristina, Ferrer, Ana, López, Pedro, Macías, Juan, Crespo, Manuel, Navarro, Maria Luisa, Iniesta, Carlos, Agea, Iván, Gómez, Juan Luis, Suárez-Zarracina, Tomás, Hernando, Asunción, Camino, Xabier, Robledano, Catalina, Ramírez, Margarita, Veloso, Sergio, Tasias, María, Bernardino, Jose Ignacio, Metola, Luis, Cairó, Mireia, de León Cano, María Teresa, Calzado, Sonia, Sarria, Cristina, Moreno, Ana, Bravo, Joaquín, Alvarez, Marta, Puerta, Teresa, Campins, Antoni A, Palacios, Rosario, Silva, Ana, de la Torre, Javier, García, Josefina, Ibarra, Sofía, Iborra, Asunción, Benito, Concha, Martín, Dolores, Pérez-Somarriba, Juncal, Prieto, Laura, Novella, María, Machuca, Isabel, Merchante, Nicolás, Morano, Luis, González, Maria Isabel, García, Luis NM, Portilla, Joaquín, Alonso, María del Mar, Pérez, Laura, Domínguez, Lourdes, Rodríguez-Arrondo, Francisco, Colomé, Joan Gregori, Padilla, Belén, Vargas, Montserrat, Castro, Iván, Castro, Juan Miguel, Sanz, Mercedes, Martinez-Lacasa, Javier, Pierola, Beatriz, Navarro, Marta, Garcia-Fraile, Lucio, Pérez-Elias, Maria Jesús, Muñoz, Ángeles, Chueca, Natalia, Carrió, Juan Carlos, Vidal, Carmen, Pérez, Carmen, Saumoy, María, Prada, José Luis, Alcaraz, Begoña, Ferrero, Oscar, Moreno, Antonio, Fenoll, Vicenta, Ruiz, Mª Pilar, Frias, Mario, Real, Luis Miguel, Miralles, Celia, Garcia, Federico, Sanz, Nieves, Sánchez-Payá, José, Pelazas, Ricardo, Rial, David, von Wichman, Miguel Ángel, Adsuar, Araceli, Gijón, Paloma, Olona, Montserrat, Calabuig, Eva, Delgado, Ana, Pérez-Martínez, Laura, Velli, Pablo, Martín-Gayo, Enrique, Gutiérrez, Carolina, Alcaraz, Maria José, Vinuesa, David, Vera, Mar, Fanjul, Francisco, Gonzalez-Domenec, Carmen, Prieto, Paula, de las Lomas, José N García, Jimeno, Amaya, López, Josefina, Merlos, Maria, Gil, Concepción, Camacho, Angela, Corma, Anais, Ocampo, Antonio, Rava, Marta, Rodríguez, Juan Carlos, Hernández, Jehovana, Bermejo, Laura, Pascual, Lidia, Pascual, Rafael, Aldamiz-Echevarría, Teresa, Rull, Anna, Cuéllar, Sandra, Escosa, Luis, Font, Roser, Madrid, Nadia, del Carmen Villalba, Maria, Martinez-Montes, Clara, Ballesteros, Juan, Murillas, Javier, Cámara, María Mar, Vidal, Asunción, Algado, José Tomas, Fernández, Marta, Pousada, Guillermo, Iribarren, Jose Antonio, Gimeno, Lina, Alemán, María Remedios, Santacreu, Mireia, Goenaga, Miguel Ángel, Tejerina, Francisco, Rodríguez-Gallego, Esther, Salavert, Miguel, Herranz, Pedro, Martinez, Marina, del Campo, Santos, Guerrero, Carlos, Ayerdi, Oskar, Homar, Francisco, de la Peña, Mireia, Meca, Marisa, Díez, Marcos, Azkune, Harkaitz, Barber, Xavier, Balsalobre, Pascual, Castellanos, Alfonso Javier, García-Bujalance, Silvia, Vivancos, Maria Jesús, Fuentes, Ana, Martin, Maria Luisa, Lopez, Iñigo, Vilchez, Helem, Lopez, Miriam, Carreres, Melissa, Ibarguren, Maialen, Agullo, Vanessa, Diez, Cristina, López-Dupla, Miguel, García, Milagros, Umerez, Maitane, Martínez-Sanz, Javier, Payeras, Antoni, Reus, Sergio, Lizardi, Aitziber, Garcia, Javier, Pérez, Leire, González-Baeza, Alicia, Anxa, Usua, González, Juan, Boix, Vicente, Kortajarena, Xabier, Pascual, Reyes, Fanciulli, Chiara, Martín-Carbonero, Maria Luz, Mellado, Maria José, Micán, Rafael, Montejano, Rocio, Montes, María Luisa, Moreno, Victoria, Pérez-Valero, Ignacio, Rúa, Guadalupe, Rodés, Berta, Sainz, Talia, Sendagorta, Elena, Stella, Natalia, Valencia, Eulalia, Velasco, Tamara, Muñoz-Fernández, María Ángeles, Torrús, Diego, Carmona, María Pilar, Roca, María, Mayoral, Mario, Vallejo, Alejandro, Serrano-Villar, Sergio, Ron, Raquel, Talavera-Rodríguez, Alba, Fernández-Felix, Borja M, Herrera, Sabina, Muriel, Alfonso, de Zárraga, Miguel Alberto, and Vivancos, María J

Published
2020
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26. Light-to-Heat Conversion of Optically Trapped Hot Brownian Particles

Author

Ortiz-Rivero, Elisa, primary, Orozco-Barrera, Sergio, additional, Chatterjee, Hirak, additional, González-Gómez, Carlos D., additional, Caro, Carlos, additional, García-Martín, María-Luisa, additional, González, Patricia Haro, additional, Rica, Raúl A., additional, and Gámez, Francisco, additional

Published
2023
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27. ¿Conocemos nuestras carencias? Analicemos el PIB

Author

Rodríguez-Vera, María-Isabel, Palop-Valverde, María, Valencia-Romero, Consuelo, and Alonso-Martín, María-Luisa

Subjects
DI. Science libraries., DK. Health libraries, Medical libraries., F. Management., J. Technical services in libraries, archives, museum., JK. Interlibrary loans.
Abstract

OBJECTIVE: To identify the scientific journals asked by users, not available in Spanish libraries. MATERIAL AND METHODS: We analyzed article applications processed during the years 2012 and 2013 (a period of important budget cuts in many libraries) by the interlending services of four hospitals of the Spanish region Castilla-La Mancha, two of them university hospitals. We identified those article that could not be served through national interlibrary loan, excluding from the sample those that were not served for the following reasons: Erroneous citation or not enough data, user cancellations because of cost or journal being binded at the time of request. RESULTS: Out of a total of 19.159 requests received from our users, we identified 1.033 requests that could not be served, corresponding to 665 journal titles. Problems encountered include: • Old references not covered by current collections • References in rare languages ​​(Chinese, Japanese ...), Only a small core of journals had a certain demand level (there were only 2 with with more that 10 requests). Among them, some titles have been identified that have been rejected by some library and obtained otherwise, usually using the lists of searches. CONCLUSIONS • We believe that the method could be extended to other libraries and would serve to identify certain gaps in our collections that could be solved cooperatively. • Given the dispersion of the titles requested, it could be more advantageous to purchase articles on demand than to subscribe to journals, but we do not have administrative mechanisms that assure us a speedy purchase. • Further updating of collective catalogs is required. • We detected some degree of "variation in practice" that influences the results. • Some requests indicated that users need some training.

Published
2014

30. APRENDIZAJE ACTIVO

Author

Montero, Juana Farfán, primary, Prieto, Pablo R., additional, and Martín, María Luisa Walliser, additional

Published
2021
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32. Sostenibilidad y Patrimonio: Aportaciones desde el Diseño.

Author

Walliser Martín, María Luisa

Subjects
CLIMATE change, COVID-19 pandemic, POLITICAL stability, ENERGY shortages, CULTURAL property
Abstract

Copyright of Cuadernos del Centro de Estudios de Diseño y Comunicación is the property of Cuadernos del Centro de Estudios de Diseno y Comunicacion and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Published
2024

36. Foto de familia. Un estudio descriptivo de los recursos de información científica en las bibliotecas virtuales del sistema sanitario público español

Author

Grupo, G17+1, Primo-Peña, Elena, Juan-Quilis, Verónica, Salas-Valero, Montserrat, Corrales, Mercedes, Lavandera-Fernández, Raquel, Páez, Virgili, Duque, Beatriz, Ribes-Cot, María-Francisca, Alonso-Martín, María-Luisa, Díaz-Ruiz, Pilar, Moreno-Romero, Francisco-Javier, Roqué, Pilar, Mejuto-Martí, Teresa, Estrada-Lorenzo, José-Manuel, García-Berges, Mayra, Sánchez-Sánchez, Juan-Antonio, Aguinaga, Enrique, Aróstegui, Ricardo, Gaminde, Idoia, and García-Martín, María-Asunción

Subjects
HN. e-journals., HP. e-resources., DK. Health libraries, Medical libraries.
Abstract

Objective: To identify and quantify scientific information resources, and to describe the present situation of libraries in the Spanish public health system. Methods and Materials: A survey sent to the heads of the health science libraries in the public health system and the virtual libraries in each Health Council. Variables: number of centres, number of users and their distribution by type, number of libraries and their staff, and shared scientific information resources. Results: 14 of the 17 Autonomous Communities have responded. All except Canarias, La Rioja and Comunidad Valenciana. In 14 communities are 201 specialized libraries, with 295 librarians, that serve more than 130.000 professionals in the public health system. The Health Councils have started the development of virtual libraries, which are in different development phases. On 2006 the libraries have subscribed, via shared access through virtual libraries, more than 17 000 journals in electronic format and 36 bibliographic databases. The presence of bibliographic management programs, meta-search engines and linksolvers is still low. Conclusions: The libraries in the public health system are subscribed to a significant volume of scientific information resources, based on the number of centers and users they give service to. A first approximation reveals that most resources overlap between the different communities. A more detailed study could corroborate those results and suggest cooperation systems between communities. The recent development of virtual libraries in the counties is promoting the access for all the health professionals to electronic resources, but would be necessary to evaluate the use of those resources. In spite of these advances, there is still reluctance to subscribe to "next generation" resources, such as meta-search engines or linksolvers.

Published
2007

41. Chitosan patterning on titanium implants

Author

Gilabert-Chirivella, Eduardo, Pérez-Feito, Ricardo, Ribeiro, Clarisse, Ribeiro, Sylvie, Correia, Daniela M., González-Martín, Maria Luisa, Manero, José María, Lanceros-Méndez, Senentxu, Ferrer, Gloria Gallego, and Gómez-Ribelles, José Luis

Published
2017
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42. Optimization of iron oxide nanoparticles for MRI-guided magnetic hyperthermia tumor therapy: reassessing the role of shape in their magnetocaloric effect.

Author

Paez-Muñoz, José María, Gámez, Francisco, Fernández-Afonso, Yilian, Gallardo, Roberto, Pernia Leal, Manuel, Gutiérrez, Lucía, de la Fuente, Jesús M., Caro, Carlos, and García-Martín, María Luisa

Abstract

Superparamagnetic iron oxide nanoparticles have hogged the limelight in different fields of nanotechnology. Surprisingly, notwithstanding the prominent role played as agents in magnetic hyperthermia treatments, the effects of nanoparticle size and shape on the magnetic hyperthermia performance have not been entirely elucidated yet. Here, spherical or cubical magnetic nanoparticles synthesized by a thermal decomposition method with the same magnetic and hyperthermia properties are evaluated. Interestingly, spherical nanoparticles displayed significantly higher magnetic relaxivity than cubic nanoparticles; however, comparable differences were not observed in specific absorption rate (SAR), pointing out the need for additional research to better understand the connection between these two parameters. Additionally, the as-synthetized spherical nanoparticles showed negligible cytotoxicity and, therefore, were tested in vivo in tumor-bearing mice. Following intratumoral administration of these spherical nanoparticles and a single exposure to alternating magnetic fields (AMF) closely mimicking clinical conditions, a significant delay in tumor growth was observed. Although further in vivo experiments are warranted to optimize the magnetic hyperthermia conditions, our findings support the great potential of these nanoparticles as magnetic hyperthermia mediators for tumor therapy. [ABSTRACT FROM AUTHOR]

Published
2023
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43. Horizontal kinetic energy analysis of tropical transition simulations with the WRF and HARMONIE‐AROME models.

Author

Calvo‐Sancho, Carlos, Bolgiani, Pedro, Subias, Álvaro, Sastre, Mariano, González‐Alemán, Juan Jesús, and Martín, María Luisa

Subjects
ENERGY budget (Geophysics), DIGITAL filters (Mathematics), METEOROLOGICAL research, WEATHER forecasting, LATENT heat, CONVECTION (Meteorology), TROPOSPHERE, KINETIC energy
Abstract

Four tropical transition (TT) events in the North Atlantic basin are simulated with the Weather Research and Forecasting (WRF) and the HARMONIE‐AROME (HAR) models to study the main features of the horizontal kinetic energy (HKE) spectra of these kinds of high‐energetic atmospheric system. Though most of the times similar results are obtained with both models, HAR shows a more intense filtering and numerical dissipation, whereas WRF tends to represent overenergized spectra in the synoptic scale and especially at smaller wavelengths. Predictability is dissimilar for the four TTs studied due to the different spectral curve slope obtained for each case, ranging from unlimited to very poor predictability at synoptic scale. Additionally, an increased HKE is presented in the middle–upper troposphere spectra. A deep analysis of the different terms involved in the equation of the spectral energy budget is presented through a detailed study of one of these TTs. The role of all of them is studied, connecting the energy spectra and the meteorological processes involved. The energy budget terms related to the nonlinear spectral transfer, the three‐dimensional divergence, and diabatic process tendencies are identified as the key ones, whereas the potential and kinetic conversion terms and the vertical flux HKE and pressure divergence terms play a secondary role on modulating the spectrum behaviour. The major energetic contributions are found at the synoptic scale, but results show that a two‐dimensional energy cascade does not fully capture the whole spectrum of a TT. The role of convection, latent heat release, and moist convection outbursts is sketched and a link within different vertical levels is found. Results show that a high‐energetic system, such as a TT, can effectively alter the atmospheric energy behaviour. [ABSTRACT FROM AUTHOR]

Published
2023
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45. Rare Recombinant GI.5[P4] Norovirus That Caused a Large Foodborne Outbreak of Gastroenteritis in a Hotel in Spain in 2021

Author

Alarcón-Linares, María Ester, primary, Moreno-Docón, Antonio, additional, Pérez-Serna, Lorena, additional, Camacho, Juan, additional, Rodriguez, Diego Sánchez, additional, Gutiérrez-Martín, María Luisa, additional, Broncano-Lavado, Antonio, additional, Echevarria, Juan-Emilio, additional, Cabrerizo, María, additional, and Fernández-García, María D., additional

Published
2023
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