896 results on '"Martin, George M."'
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2. On Immortality: An Interim Solution
3. Accelerated epigenetic aging in Werner syndrome
4. SMAD4 mutations and cross-talk between TGF-β/IFNγ signaling accelerate rates of DNA damage and cellular senescence, resulting in a segmental progeroid syndrome—the Myhre syndrome
5. Cell-to-cell variation in gene expression and the aging process
6. Introduction
7. Dementias of the Alzheimer Type: Views Through the Lens of Evolutionary Biology Suggest Amyloid-Driven Brain Aging Is Balanced Against Host Defense
8. Intrinsic Biological Aging As Underlying Pathogenetic Mechanisms in Dementias of the Alzheimer’s Type
9. The Biological Basis of Aging
10. List of Contributors
11. Neurotrophic Factors [Activity-Dependent Neurotrophic Factor (ADNF) and Basic Fibroblast Growth Factor (bFGF)] Interrupt Excitotoxic Neurodegenerative Cascades Promoted by a PS1 Mutation
12. Genetics and the Pathobiology of Ageing
13. Positional Cloning of the Werner's Syndrome Gene
14. Healthy aging: The ultimate preventative medicine
15. Accelerated epigenetic aging and DNA methylation alterations in Berardinelli–Seip congenital lipodystrophy
16. Dysfunction of the MDM2/p53 axis is linked to premature aging
17. Norman S. Wolf, D.V.M., Ph.D., 1927–2017: experimental pathologist and geroscientist
18. Extension of Murine Life Span by Overexpression of Catalase Targeted to Mitochondria
19. ERCC4 variants identified in a cohort of patients with segmental progeroid syndromes
20. TNF‐α/IFN‐γ synergy amplifies senescence‐associated inflammation and SARS‐CoV‐2 receptor expression via hyper‐activated JAK/STAT1
21. Targeted long-read sequencing identifies missing pathogenic variants in unsolved Werner syndrome cases
22. Sa1595: AN EXPERT CONSENSUS TO STANDARDIZE DEFINITIONS AND MANAGEMENT FOR EXTRA-INTESTINAL MANIFESTATIONS IN INFLAMMATORY BOWEL DISEASE
23. High incidence of BSCL2 intragenic recombinational mutation in Peruvian type 2 Berardinelli–Seip syndrome
24. WRN Mutation Update: Mutation Spectrum, Patient Registries, and Translational Prospects
25. Views on the ethical struggle for universal, high quality, affordable health care and its relevance for gerontology
26. Preface
27. About the Editors
28. New Model of Health Promotion and Disease Prevention for the 21st Century
29. DNA methylation signatures in Blood DNA of Hutchinson–Gilford Progeria syndrome
30. Abiotrophic gene action in Homo sapiens: potential mechanisms and significance for the pathobiology of aging
31. REVIEW: Healthy aging: The ultimate preventative medicine
32. POLD1 Germline Mutations in Patients Initially Diagnosed with Werner Syndrome
33. Genetic Influences on Late-Life Diseases
34. Molecular Mimicry: Histone H3 and Mycobacterial Protein Epitopes
35. Mutator Phenotype of Werner Syndrome is Characterized by Extensive Deletions
36. Dominance of the Senescent Phenotype in Heterokaryons between Replicative and Post-Replicative Human Fibroblast-Like Cells
37. Mammalian Mutator Mutant with an Aphidicolin-Resistant DNA Polymerase α
38. Reinitiation of DNA Synthesis in Senescent Human Fibroblasts upon Fusion with Cells of Unlimited Growth Potential
39. Evidence for Clonal Attenuation of Growth Potential in HeLa Cells
40. Growth Inhibition and Morphologic Modulation of Human Fibroblastlike Cells by Erythromycin
41. Genetic Linkage Evidence for a Familial Alzheimer's Disease Locus on Chromosome 14
42. Absence of Linkage of Chromosome 21q21 Markers to Familial Alzheimer's Disease
43. Activity Assays of Nine Heterogeneous Promoters in Neural and Other Cultured Cells
44. WRN mutations in Werner syndrome patients: genomic rearrangements, unusual intronic mutations and ethnic-specific alterations
45. Atypical Aicardi-Goutieres syndrome: Is the WRN locus a modifier?
46. Rapamycin decreases DNA damage accumulation and enhances cell growth of WRN-deficient human fibroblasts
47. Reduction of age-associated pathology in old mice by overexpression of catalase in mitochondria
48. Localizations of endogenous APP/APP-Proteolytic products are consistent with microtubular transport
49. Epigenetic gambling & epigenetic drift as potential mechanisms underlying the quasi-stochastic distributions of late life neurodegenerative disorders
50. The Biological Basis of Aging
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