Author: "Martin, Joel" - Searchworks@Jio Institute Digital Library Search Results

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1. Identifying ILI Cases from Chief Complaints: Comparing the Accuracy of Keyword and Support Vector Machine Methods

Author: Ferguson, Darrell, Vinson, Norman G., Morin, Jason, Martin, Joel, McClinton, Susan, and Davies, Richard
Subjects: Computer Science: Artificial Intelligence, Computer Science: Machine Learning, Artificial Intelligence, Machine Learning
Abstract: We compared the accuracy of two methods of identifying ILI cases from chief complaints. We found that a support vector machine method was more accurate than a keyword method.
Published: 2009

2. XA21-mediated resistance to Xanthomonas oryzae pv. oryzae is dose dependent

Author: Zhang, Nan, Dong, Xiaoou, Jain, Rashmi, Ruan, Deling, de Araujo, Artur Teixeira, Li, Yan, Lipzen, Anna, Martin, Joel, Barry, Kerrie, and Ronald, Pamela C
Subjects: Microbiology, Agricultural, Veterinary and Food Sciences, Biological Sciences, Agricultural Biotechnology, Genetics, Human Genome, Biotechnology, Biodefense, Infectious Diseases, Emerging Infectious Diseases, Xanthomonas, Oryza, Plant Diseases, Disease Resistance, Plants, Genetically Modified, Plant Proteins, Protein Serine-Threonine Kinases, Rice, Plant defense, XA21, Receptor-like kinase, Genetic engineering, Xanthomonas oryzae pv. oryzae, Medical and Health Sciences
Abstract: The rice receptor kinase XA21 confers broad-spectrum resistance to Xanthomonas oryzae pv. oryzae (Xoo), the causal agent of rice bacterial blight disease. To investigate the relationship between the expression level of XA21 and resulting resistance, we generated independent HA-XA21 transgenic rice lines accumulating the XA21 immune receptor fused with an HA epitope tag. Whole-genome sequence analysis identified the T-DNA insertion sites in sixteen independent T0 events. Through quantification of the HA-XA21 protein and assessment of the resistance to Xoo strain PXO99 in six independent transgenic lines, we observed that XA21-mediated resistance is dose dependent. In contrast, based on the four agronomic traits quantified in these experiments, yield is unlikely to be affected by the expression level of HA-XA21. These findings extend our knowledge of XA21-mediated defense and contribute to the growing number of well-defined genomic landing pads in the rice genome that can be targeted for gene insertion without compromising yield.
Published: 2024

3. Flexible, scalable, high channel count stereo-electrode for recording in the human brain

Author: Lee, Keundong, Paulk, Angelique C, Ro, Yun Goo, Cleary, Daniel R, Tonsfeldt, Karen J, Kfir, Yoav, Pezaris, John S, Tchoe, Youngbin, Lee, Jihwan, Bourhis, Andrew M, Vatsyayan, Ritwik, Martin, Joel R, Russman, Samantha M, Yang, Jimmy C, Baohan, Amy, Richardson, R Mark, Williams, Ziv M, Fried, Shelley I, Hoi Sang, U, Raslan, Ahmed M, Ben-Haim, Sharona, Halgren, Eric, Cash, Sydney S, and Dayeh, Shadi A
Subjects: Engineering, Biomedical Engineering, Brain Disorders, Neurosciences, Bioengineering, Mental health, Neurological, Humans, Brain, Electrodes, Action Potentials, Neurons, Electrodes, Implanted
Abstract: Over the past decade, stereotactically placed electrodes have become the gold standard for deep brain recording and stimulation for a wide variety of neurological and psychiatric diseases. Current electrodes, however, are limited in their spatial resolution and ability to record from small populations of neurons, let alone individual neurons. Here, we report on an innovative, customizable, monolithically integrated human-grade flexible depth electrode capable of recording from up to 128 channels and able to record at a depth of 10 cm in brain tissue. This thin, stylet-guided depth electrode is capable of recording local field potentials and single unit neuronal activity (action potentials), validated across species. This device represents an advance in manufacturing and design approaches which extends the capabilities of a mainstay technology in clinical neurology.
Published: 2024