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Online health communications often provide biased interpretations of evidence and have unreliable links to the source research. We tested the feasibility of a tool for matching web pages to their source evidence. From 207,538 eligible vaccination-related PubMed articles, we evaluated several approaches using 3,573 unique links to web pages from Altmetric. We evaluated methods for ranking the source articles for vaccine-related research described on web pages, comparing simple baseline feature representation and dimensionality reduction approaches to those augmented with canonical correlation analysis (CCA). Performance measures included the median rank of the correct source article; the percentage of web pages for which the source article was correctly ranked first (recall@1); and the percentage ranked within the top 50 candidate articles (recall@50). While augmenting baseline methods using CCA generally improved results, no CCA-based approach outperformed a baseline method, which ranked the correct source article first for over one quarter of web pages and in the top 50 for more than half. Tools to help people identify evidence-based sources for the content they access on vaccination-related web pages are potentially feasible and may support the prevention of bias and misrepresentation of research in news and social media.

BackgroundTechnological interventions such as mobile apps, Web-based social networks, and wearable trackers have the potential to influence physical activity; yet, only a few studies have examined the efficacy of an intervention bundle combining these different technologies. ObjectiveThis study aimed to pilot test an intervention composed of a social networking mobile app, connected with a wearable tracker, and investigate its efficacy in improving physical activity, as well as explore participant engagement and the usability of the app. MethodsThis was a pre-post quasi-experimental study with 1 arm, where participants were subjected to the intervention for a 6-month period. The primary outcome measure was the difference in daily step count between baseline and 6 months. Secondary outcome measures included engagement with the intervention and system usability. Descriptive and inferential statistical tests were conducted; posthoc subgroup analyses were carried out for participants with different levels of steps at baseline, app usage, and social features usage. ResultsA total of 55 participants were enrolled in the study; the mean age was 23.6 years and 28 (51%) were female. There was a nonstatistically significant increase in the average daily step count between baseline and 6 months (mean change=14.5 steps/day, P=.98, 95% CI –1136.5 to 1107.5). Subgroup analysis comparing the higher and lower physical activity groups at baseline showed that the latter had a statistically significantly higher increase in their daily step count (group difference in mean change from baseline to 6 months=3025 steps per day, P=.008, 95% CI 837.9-5211.8). At 6 months, the retention rate was 82% (45/55); app usage decreased over time. The mean system usability score was 60.1 (SD 19.2). ConclusionsThis study showed the preliminary efficacy of a mobile social networking intervention, integrated with a wearable tracker to promote physical activity, particularly for less physically active subgroups of the population. Future research should explore how to address challenges faced by physically inactive people to provide tailored advices. In addition, users’ perspectives should be explored to shed light on factors that might influence their engagement with the intervention.

BackgroundGout is a form of chronic arthritis caused by elevated serum uric acid (SUA) and culminates in painful gout attacks. Although effective uric acid-lowering therapies exist, adherence is low. This is partly due to the lack of support for patients to self-manage their disease. Mobile health apps have been used in the self-management of chronic conditions. However, not all are developed with patients, limiting their effectiveness. ObjectiveThe objective of our study was to collect feedback from gout patients to design an effective gout self-management app. MethodsTwo descriptive qualitative studies were conducted. In Study 1, researchers developed a short educational video and written materials about gout management, designed to be embedded into an app; 6 interviews and 1 focus group were held with gout patients to gather feedback on these materials. Usability testing in Study 2 involved additional gout patients using a pilot version of Healthy.me Gout, a gout self-management app, for 2 weeks. Following the trial, patients participated in an interview about their experiences using the app. ResultsPatients viewed the gout educational material positively, appreciating the combined use of video, text, and images. Patients were receptive to using a mobile app to self-manage their gout. Feedback about Healthy.me Gout was generally positive with patients reporting that the tracking and diary features were most useful. Patients also provided suggestions for improving the app and educational materials. ConclusionsThese studies involved patients in the development of a gout self-management app. Patients provided insight to improve the app’s presentation and usability and general lessons on useful features for chronic disease apps. Gout patients enjoyed tracking their SUA concentrations and gout attack triggers. These capabilities can be translated into self-management apps for chronic diseases that require monitoring of pathological values, medication adherence, or symptoms. Future health app design should integrate patient input and be developed iteratively to address concerns identified by patients.

Invasive neural implants allow for high-resolution bidirectional communication with the nervous tissue and have demonstrated the ability to record neural activity, stimulate neurons, and sense neurochemical species with high spatial selectivity and resolution. However, upon implantation, they are exposed to a foreign body response which can disrupt the seamless integration of the device with the native tissue and lead to deterioration in device functionality for chronic implantation. Modifying the device surface by incorporating bioactive coatings has been a promising approach to camouflage the device and improve integration while maintaining device performance. In this work, we explored the novel application of a chondroitin sulfate (CS) based hydrophilic coating, with anti-fouling and neurite-growth promoting properties for neural recording electrodes. CS-coated samples exhibited significantly reduced protein-fouling in vitro which was maintained for up to 4-weeks. Cell culture studies revealed a significant increase in neurite attachment and outgrowth and a significant decrease in microglia attachment and activation for the CS group as compared to the control. After 1-week of in vivo implantation in the mouse cortex, the coated probes demonstrated significantly lower biofouling as compared to uncoated controls. Like the in vitro results, increased neuronal population (neuronal nuclei and neurofilament) and decreased microglial activation were observed. To assess the coating's effect on the recording performance of silicon microelectrodes, we implanted coated and uncoated electrodes in the mouse striatum for 1 week and performed impedance and recording measurements. We observed significantly lower impedance in the coated group, likely due to the increased wettability of the coated surface. The peak-to-peak amplitude and the noise floor levels were both lower in the CS group compared to the controls, which led to a comparable signal-to-noise ratio between the two groups. The overall single unit yield (% channels recording a single unit) was 74% for the CS and 67% for the control group on day 1. Taken together, this study demonstrates the effectiveness of the polysaccharide-based coating in reducing biofouling and improving biocompatibility for neural electrode devices. [ABSTRACT FROM AUTHOR]

Study examined attitudes of adolescents toward aspects of marriage and family life. The majority expressed negative attitudes toward divorce and viewed marriage as a lifelong commitment. While about one third expressed positive attitudes toward premarital sex, a majority indicated they would engage or had engaged in sex. The adolescents demonstrated a growing acceptance of premarital counseling and psychoeducational interventions. (Contains 39 references.) (Author/ADT)

Societal trends indicate ambivalent attitudes about marriage, specifically a greater acceptance of divorce and nontraditional living arrangements. This paper examines adolescent attitudes toward marriage and their association with premarital sexual activity and cohabitation. Recommendations for helping adolescents understand the realities of marriage and family life are shared. (Author)

Abstract This article examines current societal trends in marriage and family life in the United States, as well as how these trends impact adolescent values and behaviors. The postponement of [...]

In the U.S., modifications in family structure and in attitudes concerning marriage and family life have been numerous. Areas such as sexual behavior and alternative living arrangements have become highly varied and nontraditional compared to past generations. This study examined the attitudes of adolescents toward aspects of marriage and family life. The majority of adolescents expressed negative attitudes toward divorce and viewed marriage as a lifelong commitment. While only about a third of the adolescents expressed positive attitudes toward premarital sex, a majority indicated they would engage in sexual intercourse before marriage, or already have. Interestingly, about half of the adolescents held positive attitudes toward cohabitation. Lastly, the adolescents demonstrated a growing acceptance of premarital counseling and psychoeducational interventions regarding marriage and family life., Nontraditional behaviors with respect to sex, family, and gender roles have become increasingly widespread and more socially accepted (Barber & Axinn, 1998; Lye & Waldron, 1997; Werner-Wilson, 1998; Wu & [...]

Paige D. Martin, Director of Special Education/School Psychologist, Rootstown School District, Rootstown, Ohio. Maggie Martin, Chief Administrative Officer, Northside Urban Pathways, Pittsburgh, Pennsylvania. Reprint requests to Don Martin, Department of Counseling, Youngstown State University, One University Plaza, Youngstown, Ohio 44555. Electronic mail may be sent to dmartin@cc.ysu.edu., ABSTRACT Societal trends indicate ambivalent attitudes about marriage. Specifically, there is greater acceptance of divorce and nontraditional living arrangements such as cohabitation, as well as acceptance and prevalence of premarital [...]

Presents information concerning stereotypical mannerisms and relationship development of legally blind and visually impaired children. Discusses counseling methods that are useful with this population. (MKA)