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Zusammenfassung Der Beitrag stellt den digitalen Lesesaal (DLS) der Staatsarchive Basel-Stadt und St.Gallen vor. Ziele, Vorarbeiten und agile Umsetzung sowie Architektur, Design und Funktionen werden auf dem aktuellen Stand präsentiert. Abschließend wird das Vorgehen zur Einführung skizziert. Der DLS ist die zentrale Schnittstelle zum Archivgut. Er schafft direkten Zugang zu digitalem Archivgut und bildet den gesamten Benutzungsprozess des Archivs ab. Der DLS bietet Werkzeuge für Vermittlung von Archivgut und ermöglicht mit Tools für User Generated Content auch Partizipation von Benutzenden.

Climate change is causing major shifts in the dynamics of the cryosphere, leading to sea-level rise, glacier break-off events, flooding, and landslides. Geological, thermodynamic and hydraulic processes at the base of an ice mass play a central role in ice flow dynamics, and understanding these is imperative for predicting ice body behavior in a changing climate. To this end, sustained ambient vibrations in glaciated environments can be used to monitor subglacial conditions over significant spatial extent with relatively low-cost acquisition.In earthquake seismology, a well-established methodology to investigate subsurface properties is the horizontal-to-vertical spectral ratio (H/V) of ambient seismic ground unrest. In cryoseismology, the H/V approach is already used to invert for velocity profiles of ice or firn, to obtain bedrock topography and to identify the presence of basal sediments. To date, only a few hours of seismic vibration records are typically used. Yet in such short time records, biases may arise because of the dynamic character of the glacier. Seismic resonances within the soft ice layer and resulting H/V ratios are expected to vary with changes in subglacial hydraulic conditions.We propose to leverage temporal variations in H/V spectra to investigate subglacial processes. As a case study, we first focus on the Glacier de la Plaine Morte (Switzerland), where a seismic array was deployed for four months in summer of 2016. During this time, an ice-marginal lake formed and suddenly drained through and under the glacier, making this seismic record ideal for our purposes. This drainage event is well recorded and strongly influences the H/V in terms of amplitude and resonance frequency. We next present ambient H/V measurements of the Sermeq Kujalleq in Kangia (also known as Jakobshavn Isbræ), one of Greenland’s largest outlet glaciers. Here, the H/V spectra show multiple resonances over time, whose origin we discuss in more detail. For both our study cases, separating variations in source and medium properties is pivotal. Tackling this challenge provides glaciologists with a valuable tool to investigate the poorly accessible subglacial environment, which holds the key to our understanding of ice flow and eustatic sea level rise.

Motor learning is a multi-stage process, in which the involvement of different brain regions is related to the specific stage. We aimed at characterising short timescale changes of brain activity induced by motor sequence learning. Twenty healthy volunteers performed a serial reaction time task during an MRI session in a 3 T scanner. The task consisted of two conditions: repeated and random, that were compared over the whole fMRI run, as well as within sections, to investigate brain activity modulating related to the learning stage. The whole fMRI run analysis showed a stronger response for the repeated condition in fronto-parietal regions, cerebellum and thalamus. The analysis on sections showed initially increased right cerebellar activity. In the subsequent phase, bilateral cerebellar activity was observed, while no increased activity was seen in the last phase, when the learning was established. At the neocortical level, the repeated condition showed stronger activity at first in fronto-parietal regions bilaterally, then lateralized to the right hemisphere in the last learning phase. This study showed short time scale brain activity modulation in cortical and cerebellar regions with involvement of different brain regions over the learning process not restricted to the motor circuit.

Summary Objectives/Hypothesis Medialization thyroplasty (MT) has become a prominent method for treating glottal insufficiency. This study aimed to visualize the biomechanical influence of a medialization implant on arytenoid cartilage, particularly on the length and level of paralyzation in the vocal fold, in patients with unilateral vocal fold paralysis. Study Design Prospective study. Methods We recruited 15 patients (10 men, 5 women) with unilateral vocal fold paralysis that underwent MT with a Montgomery® thyroplasty implant. We performed high-resolution computed tomography of the arytenoid cartilage before and after MT and analyzed the three-dimensional images. To visualize the movement of the arytenoid and to measure the lengthening of the vocal fold, we superimposed pre- and postoperative 3D images with MIMICS software. Results On the affected side, the implant pushed the arytenoid backwards. In addition, the vocal process of the arytenoid was inwardly rotated. These movements resulted in an elongated, augmented vocal fold on the affected side. Conclusion MT led to an elongated, medialized vocal fold on the treated side. After the intervention, the vocal folds on both sides were the same length in the phonatory position.